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https://www.readbyqxmd.com/read/28727659/patient-release-criteria-following-radioactive-iodine-131-treatment-in-the-light-of-international-practice-where-does-south-africa-fit-in
#1
Modisenyane S Mongane, William I D Rae
The release from hospital of patients treated with radioactive iodine-131 (I) remains a controversial issue as a result of the range of guidelines implemented by national regulatory bodies responsible for radiation protection in various countries worldwide. The aim of this study was to review and analyse the literature on patient release criteria (PRC) applied internationally in an attempt to achieve a justifiable approach to setting equivalent criteria in South Africa. In 2016, the South African Department of Health, Directorate: Radiation Control added conditions (numbers 50 and 90), to licences to use radioactive nuclides...
July 19, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28727483/pharmacological-treatment-of-tardive-dyskinesia-recent-developments
#2
Stanley N Caroff, E Cabrina Campbell, Benjamin Carroll
Tardive dyskinesia (TD) occurs in patients receiving antipsychotic treatment with dopamine receptor antagonists. Despite the prevalence of TD and its negative impact on patients' lives, there has been a lack of approved treatments and limited evidence from controlled trials of pharmacological treatment. Areas covered: PubMed was searched for English-language papers published during 2007-2016 using terms "tardive dyskinesia" or "drug-induced movement disorder", and "treatment". Studies evaluating pharmacological agents for the treatment of TD were selected...
July 20, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28726141/transoral-robotic-thyroidectomy-lessons-learned-from-an-initial-consecutive-series-of-24-patients
#3
Hoon Yub Kim, Young Jun Chai, Gianlorenzo Dionigi, Angkoon Anuwong, Jeremy D Richmon
BACKGROUND: Transoral thyroid surgery is an ideal method for minimally invasive thyroidectomy, as there is less flap dissection during the procedure and no postoperative scars. Nonetheless, technical obstacles have precluded the wide dissemination of this procedure. We present the surgical procedures and outcomes of transoral robotic thyroidectomy (TORT). METHODS: From September 2012 to June 2016, we performed TORT at Korea University Hospital. We used three intraoral ports and a single axillary port for the system's four robotic arms...
July 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28725275/ash-meeting-2016-developments-in-hemostaseology
#4
REVIEW
Clemens Feistritzer, Birgit Mosheimer
During the annual meeting of the American Society of Hematology (ASH) in San Diego/California, novel developments in the field of hemostaseology were presented. Alternative treatment strategies besides factor replacement were discussed for patients with hemophilia. One of the highlights of the meeting in this year's plenary session was the presentation of successful adeno-associated virus mediated gene transfer in patients with hemophilia B leading to sustained elevation of factor IX:C (FIX:c). Other alternative treatment approaches in patients with hemophilia A may include bispecific antibodies mimicking factor VIIIa (FVIIIa) activity or disrupting anticoagulant proteins...
2017: Memo
https://www.readbyqxmd.com/read/28723515/understanding-mechanisms-of-resistance-in-metastatic-castration-resistant-prostate-cancer-the-role-of-the-androgen-receptor
#5
REVIEW
Derya Tilki, Edward M Schaeffer, Christopher P Evans
CONTEXT: After initiation of androgen deprivation therapy (ADT), most patients progress to castration-resistant prostate cancer (CRPC) within 2 or 3 yr. In the USA, approximately 67000 men are estimated to have metastatic CRPC. OBJECTIVE: To provide an overview of different mechanisms driving resistance to therapy in metastatic CRPC, with a focus on androgen receptor (AR)-dependent pathways. EVIDENCE ACQUISITION: A Medline search via PubMed was performed using the keywords metastatic castration resistant prostate cancer (mCRPC), castration-resistant, CRPC, prostate cancer, androgen resistance, hormone-refractory, hormone-independent, androgen receptor, and androgen receptor axis...
December 2016: European Urology Focus
https://www.readbyqxmd.com/read/28723513/the-natural-history-and-outcome-predictors-of-metastatic-castration-resistant-prostate-cancer
#6
REVIEW
Robert J van Soest, Jason A Efstathiou, Cora N Sternberg, Bertand Tombal
CONTEXT: Biomarkers for the treatment of metastatic castration-resistant prostate cancer (mCRPC) are urgently needed by clinicians to facilitate treatment decisions. OBJECTIVE: To review current prognostic and predictive biomarkers in mCRPC. EVIDENCE ACQUISITION: We performed a nonsystematic review of the literature from 2004 to August 2016 by searching in Medline. Cross-matching references were used to search for additional articles. We reviewed clinical research and review articles written in the English language...
December 2016: European Urology Focus
https://www.readbyqxmd.com/read/28723491/robotic-surgery-for-renal-cell-carcinoma-with-vena-caval-tumor-thrombus
#7
REVIEW
Ronney Abaza, Daniel D Eun, Michele Gallucci, Inderbir S Gill, Mani Menon, Alexandre Mottrie, Ahmad Shabsigh
CONTEXT: Robotic surgery has significantly advanced the minimally-invasive management of kidney tumors with extension into the inferior vena cava requiring caval cross-clamping and tumor thrombectomy. Additional techniques have recently been developed to continue the evolution of this complex procedure and extend its indications. OBJECTIVE: To review the current state of the art as regards robotic nephrectomy with inferior vena cava thrombectomy (RNIT). EVIDENCE ACQUISITION: A systematic review of the Medline database was performed...
December 15, 2016: European Urology Focus
https://www.readbyqxmd.com/read/28722761/a-meta-ethnographic-synthesis-of-midwives-and-nurses-experiences-of-adverse-labour-and-birth-events
#8
REVIEW
Rakime Elmir, Jackie Pangas, Hannah Dahlen, Virginia Schmied
INTRODUCTION: Health professionals are frequently exposed to traumatic events due to the nature of their work. While traumatic and adverse labour and birth events experienced by women are well researched, less attention has been given to midwives' and nurses' experiences of these events and the impact it has on their lives. AIM: To undertake a meta-ethnographic study of midwives' and nurses' experiences of adverse labour and birth events. METHODS: Scopus, CINHAL PLUS, MEDLINE and PUBMED databases were searched using subject headings and keywords...
July 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28721601/high-survivorship-and-few-complications-with-cementless-total-wrist-arthroplasty-at-a-mean-followup-of-9-years
#9
Joseph A Gil, Robin N Kamal, Eugene Cone, Arnold-Peter C Weiss
BACKGROUND: Total wrist arthroplasty (TWA) has been described as traditionally being performed with fixation in the radius and carpus with cement. The TWA implant used in our series has been associated with promising results in studies with up to 6 years followup; however, studies evaluating survivorship, pain, and function with this implant are limited. QUESTION/PURPOSE: (1) To report ROM and pain scores after wrist reconstruction with cementless fourth-generation TWA at a mean followup of 9 years (range, 4...
July 18, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28720366/the-evolving-role-of-retrograde-intrarenal-surgery-in-the-treatment-of-urolithiasis
#10
REVIEW
Francesco Sanguedolce, Giorgio Bozzini, Ben Chew, Panagiotis Kallidonis, Jean de la Rosette
CONTEXT: Retrograde intrarenal surgery has gained substantial popularity worldwide thanks to continuous improvements in technology and techniques, and is now considered one of the first-line treatment options for active removal of renal stones. OBJECTIVE: To provide a comprehensive synthesis of the main evidences in literature on the current management of kidney stones by means of retrograde intrarenal surgery (RIRS). EVIDENCE ACQUISITION: A review of literature has been conducted using search string "retrograde intrarenal surgery OR flexible ureteroscop* OR ureterorenoscop*", without any language restriction; PubMed, Embase, and Scopus databases were searched in November 2016...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720290/how-to-improve-sleep-in-a-neonatal-intensive-care-unit-a-systematic-review
#11
Agnes van den Hoogen, Charlotte J Teunis, Renée A Shellhaas, Sigrid Pillen, Manon Benders, Jeroen Dudink
There is increasing evidence that sleep plays a major role in the development of neural pathways in the neonatal brain. Several studies have suggested evidence-based approaches to improve sleep for infants admitted to the neonatal intensive care unit (NICU); however, in many neonatal centers very few of these strategies seem to be implemented in routine care. OBJECTIVE: To systematically review the literature to determine interventions promoting neonatal sleep on the NICU, in order to develop key guidelines to improve neonatal sleep...
July 15, 2017: Early Human Development
https://www.readbyqxmd.com/read/28720141/selecting-and-implementing-overview-methods-implications-from-five-exemplar-overviews
#12
Alex Pollock, Pauline Campbell, Ginny Brunton, Harriet Hunt, Lise Estcourt
BACKGROUND: Overviews of systematic reviews are an increasingly popular method of evidence synthesis; there is a lack of clear guidance for completing overviews and a number of methodological challenges. At the UK Cochrane Symposium 2016, methodological challenges of five overviews were explored. Using data from these five overviews, practical implications to support methodological decision making of authors writing protocols for future overviews are proposed. METHODS: Methods, and their justification, from the five exemplar overviews were tabulated and compared with areas of debate identified within current literature...
July 18, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28717618/plantar-fasciitis-in-athletes-diagnostic-and-treatment-strategies-a-systematic-review
#13
REVIEW
Federica Petraglia, Ileana Ramazzina, Cosimo Costantino
BACKGROUND: Plantar fasciitis (PF) is reported in different sports mainly in running and soccer athletes. Purpose of this study is to conduct a systematic review of published literature concerning the diagnosis and treatment of PF in both recreational and élite athletes. The review was conducted and reported in accordance with the PRISMA statement. METHODS: The following electronic databases were searched: PubMed, Cochrane Library and Scopus. As far as PF diagnosis, we investigated the electronic databases from January 2006 to June 2016, whereas in considering treatments all data in literature were investigated...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28713697/safe-implementation-of-retroauricular-robotic-and-endoscopic-neck-surgery-in-south-america
#14
REVIEW
Renan Bezerra Lira, Thiago Celestino Chulam, Luiz Paulo Kowalski
In the last three decades, otolaryngology and head and neck oncological surgery have shown remarkable progress with the development of several modalities of endoscopic-assisted minimally invasive surgeries. More recently, the Da Vinci robotic surgery system has promoted the development of several surgical approaches with less morbidity and better cosmetic results, including the transaxillary and retroauricular approaches for thyroid surgery and neck dissections. In South America, there are several shortcomings regarding financial resources as well as the lack of support for innovation leading to a significant delay in adoption of numerous technological advances in medical practice...
June 2017: Gland Surgery
https://www.readbyqxmd.com/read/28713066/approaches-for-stricture-prevention-after-esophageal-endoscopic-resection
#15
REVIEW
Seiichiro Abe, Prasad G Iyer, Ichiro Oda, Nobuo Kanai, Yutaka Saito
BACKGROUND AND AIMS: Endoscopic resection of extensive esophageal lesions has become more common as endoscopic resection techniques and equipment has developed. However, extensive esophageal endoscopic resections can cause postoperative esophageal strictures, which have a negative impact on the quality of life of patients. We aimed to review current treatments and innovative approaches to prevent esophageal strictures after widespread endoscopic resection of esophageal lesions. METHODS: We performed a comprehensive literature search using predetermined search terms from 2000 to 2016 to identify relevant articles and summarized their results as a narrative review...
July 13, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28712784/effects-of-interventions-with-therapeutic-suits-clothing-on-impairments-and-functional-limitations-of-children-with-cerebral-palsy-a-systematic-review
#16
REVIEW
Kênnea M Almeida, Sérgio T Fonseca, Priscilla R P Figueiredo, Amanda A Aquino, Marisa C Mancini
BACKGROUND: Therapeutic suits or clothing whether associated with intensive protocols or not, became popular in the rehabilitation of children with cerebral palsy. Studies have reported positive effects of these suits on children's posture, balance, motor function and gait. A summary of current literature may help guide therapeutic actions. OBJECTIVE: To evaluate the available evidence on the effects of interventions based on the use of therapeutic suits in the treatment of impairments and functional limitations of children with cerebral palsy...
July 5, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28711439/updates-on-k13-mutant-alleles-for-artemisinin-resistance-in-plasmodium-falciparum
#17
REVIEW
Myo Thura Zaw, Nor Amalina Emran, Zaw Lin
BACKGROUND: In the fight against malaria caused by Plasmodium falciparum, the successes achieved by artemisinin were endangered by resistance of the parasites to the drug. Whole genome sequencing approach on artemisinin resistant parasite line discovered k13 gene associated with drug resistance. In vitro and in vivo studies indicated mutations in the k13 gene were linked to the artemisinin resistance. METHODOLOGY: The literatures published after April, 2015 up to December, 2016 on k13 mutant alleles for artemisinin resistance in Plasmodium falciparum and relevant literatures were comprehensively reviewed...
June 29, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28711284/financialisation-in-health-care-an-analysis-of-private-equity-fund-investments-in-turkey
#18
Ipek Eren Vural
The 2007-2008 global financial crisis revived interest in the impacts of financial markets and actors on our social and economic life. Nevertheless, research on health care financialisation remains scant. This article presents findings from research on one modality of financial investments in health care: global private equity funds' investments in private hospitals. Adopting a political economy approach, it analyses the drivers and impacts of the upsurge of global private equity investments in the Turkish private hospital sector amid the global financial crisis...
June 9, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28709967/advances-in-asthma-2016-designing-individualized-approaches-to-management
#19
William C Anderson, Andrea Apter, Cullen M Dutmer, Daniel A Searing, Stanley J Szefler
In this years Advances in Asthma review we discuss viral infections in asthma and potential therapeutic agents, the microbiome, novel genetic associations with asthma, air quality and climate effects on asthma, exposures during development and long term sequelae of childhood asthma, patient centered outcome research, and precision medicine. In addition, we discuss application of biomarkers to precision medicine, and new information on asthma medications. New evidence indicates that rhinovirus-triggered asthma exacerbations become more severe as the degree of sensitization to dust mite and mouse increase...
July 11, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28709853/evaluation-of-current-trends-and-recent-development-in-insulin-therapy-for-management-of-diabetes-mellitus
#20
REVIEW
Muhammad Sarfraz Nawaz, Kifayat Ullah Shah, Tahir Mehmood Khan, Asim Ur Rehman, Haroon Ur Rashid, Sajid Mahmood, Shahzeb Khan, Muhammad Junaid Farrukh
OBJECTIVE: Diabetes mellitus is a major health problem in developing countries. There are various insulin therapies to manage diabetes mellitus. This systematic review evaluates various insulin therapies for management of diabetes mellitus worldwide. This review also focuses on recent developments being explored for better management of diabetes mellitus. RESEARCH DESIGN AND METHOD: We reviewed a number of published articles from 2002 to 2016 to find out the appropriate management of diabetes mellitus...
July 8, 2017: Diabetes & Metabolic Syndrome
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