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https://www.readbyqxmd.com/read/29782615/feasibility-study-applying-a-parametric-model-as-the-design-generator-for-3d-printed-orthosis-for-fracture-immobilization
#1
Jianyou Li, Hiroya Tanaka
Background: Applying 3D printing technology for the fabrication of custom-made orthoses provides significant advantages, including increased ventilation and lighter weights. Currently, the design of such orthoses is most often performed in the CAD environment, but creating the orthosis model is a time-consuming process that requires significant CAD experience. This skill gap limits clinicians from applying this technology in fracture treatment. The purpose of this study is to develop a parametric model as the design generator for 3D-printed orthoses for an inexperienced CAD user and to evaluate its feasibility and ease of use via a training and design exercise...
2018: 3D printing in medicine
https://www.readbyqxmd.com/read/29775080/mindfulness-meditation-and-interprofessional-cardiopulmonary-resuscitation-a-mixed-methods-pilot-study
#2
Diana J Kelm, Jennifer L Ridgeway, Becca L Gas, Monali Mohan, David A Cook, Darlene R Nelson, Roberto P Benzo
PROBLEM: Mindfulness training includes mindfulness meditation, which has been shown to improve both attention and self-awareness. Medical providers in the intensive care unit often deal with difficult situations with strong emotions, life-and-death decisions, and both interpersonal and interprofessional conflicts. The effect of mindfulness meditation training on healthcare providers during acute care tasks such as cardiopulmonary resuscitation remains unknown. Mindfulness meditation has the potential to improve provider well-being and reduce stress in individuals involved in resuscitation teams, which could then translate into better team communication and delivery of care under stress...
May 18, 2018: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/29759007/contemporary-trends-emerging-in-epigenomics-and-metabolism
#3
Assam El-Osta
Diabetes is the disease of our time. It is a complex disorder. It is increasingly appreciated that genetic factors cannot fully explain susceptibility to diabetic complications. For almost a decade, the epigenetics field has grown tremendously becoming an alternative but integral component of how we interpret gene regulation. Some consider the field an epiphenomenon with an evidence base awaiting critical testing. The advent of experimental tools combined with the development of research methods have brought with the field technological advancements that allow scientists to assess ideas that have not yet been tested critically...
May 15, 2018: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29755598/efficacy-of-an-sms-based-smoking-intervention-using-message-self-authorship-a-pilot-study
#4
Krista L DeStasio, Anne P Hill, Elliot T Berkman
Introduction: Text-message-based interventions hold great potential for intervention and are increasingly feasible, given advances in information technology. Aims: This pilot randomized controlled trial (RCT) aims to compare the efficacy of self-versus expert-authored content delivered via text-messaging for smoking cessation. Methods: Sixty-two participants aged 25-66 attended laboratory sessions pre- and post-30 days of text-messaging intervention...
March 2018: Journal of Smoking Cessation
https://www.readbyqxmd.com/read/29753333/3d-treatment-planning-systems
#5
REVIEW
Cheng B Saw, Sicong Li
Three-dimensional (3D) treatment planning systems have evolved and become crucial components of modern radiation therapy. The systems are computer-aided designing or planning softwares that speed up the treatment planning processes to arrive at the best dose plans for the patients undergoing radiation therapy. Furthermore, the systems provide new technology to solve problems that would not have been considered without the use of computers such as conformal radiation therapy (CRT), intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT)...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29751162/recent-advances-in-dna-nanotechnology
#6
REVIEW
Pongphak Chidchob, Hanadi F Sleiman
DNA is a powerful guiding molecule to achieve the precise construction of arbitrary structures and high-resolution organization of functional materials. The combination of sequence programmability, rigidity and highly specific molecular recognition in this molecule has resulted in a wide range of exquisitely designed DNA frameworks. To date, the impressive potential of DNA nanomaterials has been demonstrated from fundamental research to technological advancements in materials science and biomedicine. This review presents a summary of some of the most recent developments in structural DNA nanotechnology regarding new assembly approaches and efforts in translating DNA nanomaterials into practical use...
May 8, 2018: Current Opinion in Chemical Biology
https://www.readbyqxmd.com/read/29749836/exploring-biology-a-vision-and-change-disciplinary-first-year-seminar-improves-academic-performance-in-introductory-biology
#7
Caroline J Wienhold, Janet Branchaw
The transition to college is challenging for most students, especially those who aspire to major in the science, technology, engineering, or mathematics disciplines, in which introductory courses can be large and instruction less than optimal. This paper describes a novel, disciplinary first-year seminar (FYS) course, Exploring Biology, designed to address many of the challenges facing aspiring biology students beginning their academic careers at a large public research university. The course addresses typical FYS goals, such as community building, introduction to resources, and academic skill development, and introduces students to the core concepts of biology defined in the 2011 Vision and Change report...
June 2018: CBE Life Sciences Education
https://www.readbyqxmd.com/read/29742903/technology-based-behavioral-interventions-for-daily-activities-and-supported-ambulation-in-people-with-alzheimer-s-disease
#8
Giulio E Lancioni, Nirbhay N Singh, Mark F O'Reilly, Jeff Sigafoos, Fiora D'Amico, Dominga Laporta, Maria Giovanna Cattaneo, Antonella Scordamaglia, Katia Pinto
OBJECTIVES: These 2 studies evaluated technology-based behavioral interventions for promoting daily activities and supported ambulation in people with mild-to-moderate and moderate-to-severe Alzheimer's disease, respectively. METHODS: Study 1 included 8 participants who were taught to start and carry out daily activities on their own using a tablet or smartphone device, which provided activity reminders, step instructions, and praise. Study 2 included 9 participants who were taught to engage in brief periods of ambulation using a walker combined with a tilt microswitch and a notebook computer, which monitored step responses and provided stimulation and prompts...
January 1, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/29729097/3d-printed-model-for-hands-on-training-in-dental-traumatology
#9
M Reymus, C Fotiadou, R Hickel, C Diegritz
AIM: To assess the feasibility of creating a realistic model for hands-on training in dental traumatology using 3D printing technology, and then to investigate the added value of working with the website dentaltraumaguide. org. METHODOLOGY: With the use of special software applications, a model was designed based on the CBCT of the maxilla of a real patient that imitated several traumatic dental injuries. The model was reproduced using a stereolithographic printer in order to use the specimens in a hands-on training course on dental traumatology for undergraduate students in their final year in the Department of Conservative Dentistry and Periodontology in Munich, Germany...
May 5, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29725739/the-combination-of-expanded-scalp-flap-and-800-nm-diode-laser-in-the-reconstruction-of-forehead-defect
#10
Yang Li, Weiyang Li, Chaohua Liu, Qing Yang, Ping Xue, Hengxin Liu, Jiangbo Cui, Jianke Ding, Yingjun Su, Xianjie Ma
Skin grafting is often the first choice for closing forehead defects. However, the aesthetics of skin grafting-reconstructed forehead defects are still not accepted by a large number of patients. With the technological advancement of laser hair removal, scalp flaps have been considered as donors for reconstruction of forehead defects. We evaluated 10 cases of forehead defect reconstructions with expanded scalp flaps followed by hair removal by an 800 nm diode laser. All flaps survived uneventfully and underwent 4-6 laser treatments for hair removal...
May 3, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29725667/telehealth-management-of-parkinson-s-disease-using-wearable-sensors-an-exploratory-study
#11
Dustin A Heldman, Denzil A Harris, Timothy Felong, Kelly L Andrzejewski, E Ray Dorsey, Joseph P Giuffrida, Barry Goldberg, Michelle A Burack
Background: Parkinson's disease (PD) motor symptoms can fluctuate and may not be accurately reflected during a clinical evaluation. In addition, access to movement disorder specialists is limited for many with PD. The objective was to assess the impact of motion sensor-based telehealth diagnostics on PD clinical care and management. Methods: Eighteen adults with PD were randomized to control or experimental groups. All participants were instructed to use a motion sensor-based monitoring system at home one day per week, for seven months...
September 2017: Digital Biomarkers
https://www.readbyqxmd.com/read/29718516/after-the-medication-error-recent-nursing-graduates-reflections-on-adequacy-of-education
#12
Linda A Treiber, Jackie H Jones
BACKGROUND: The purpose of this study was to better understand individual- and system-level factors surrounding making a medication error from the perspective of recent Bachelor of Science in Nursing graduates. METHOD: Online survey mixed-methods items included perceptions of adequacy of preparatory nursing education, contributory variables, emotional responses, and treatment by employer following the error. RESULTS: Of the 168 respondents, 55% had made a medication error...
May 1, 2018: Journal of Nursing Education
https://www.readbyqxmd.com/read/29717454/dna-methylation-analysis-using-droplet-digital-pcr
#13
Ming Yu, Tai J Heinzerling, William M Grady
Droplet digital (ddPCR) is a recent advance in PCR technology that enables the precise detection and absolute quantification of nucleic acid target sequences and that has a range of applications for both research and clinical diagnostic studies. Here, we discuss the parameters important in the design and performance of ddPCR for the detection and quantification of methylated DNA. We provide explicit instructions for conducting methylation specific ddPCR (aka MethyLight ddPCR). We also present an example that demonstrates the sensitivity and precision of the method for detecting methylated DNA in the promoter region of mir342/EVL, a potential DNA methylation biomarker for colon cancer risk...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29707650/using-an-audience-response-system-smartphone-app-to-improve-resident-education-in-the-pediatric-intensive-care-unit
#14
Hoyoung Chung, Tom Kallay, Nick Anas, Diana Bruno, Jose Decamps, Darci Evans, Niveditha Vilasagar, Richard B Mink
In the Pediatric Intensive Care Unit (PICU), most teaching occurs during bedside rounds, but technology now provides new opportunities to enhance education. Specifically, smartphone apps allow rapid communication between instructor and student. We hypothesized that using an audience response system (ARS) app can identify resident knowledge gaps, guide teaching, and enhance education in the PICU. Third-year pediatric residents rotating through the PICU participated in ARS-based education or received traditional teaching...
January 2018: Journal of Medical Education and Curricular Development
https://www.readbyqxmd.com/read/29706276/comparison-of-faculty-and-student-self-assessment-scores-of-aseptic-technique-skills-and-the-impact-of-video-review-on-self-awareness-for-second-year-pharmacy-students
#15
Eliza A Dy-Boarman, Beth Diehl, Wendy Mobley-Bukstein, Michelle M Bottenberg, Ginelle A Bryant, Hannah Sauer
BACKGROUND AND PURPOSE: Educating students about aseptic technique presents many challenges. Students at Drake University have limited exposure to this skill outside of the classroom setting, and students have previously shown a lack of awareness related to their own aseptic technique skills. One approach to developing self-awareness in this area may be the incorporation of activities involving video viewing and self-reflection. EDUCATIONAL ACTIVITY AND SETTING: Second-year pharmacy students in the Intermediate Pharmacy Skills and Applications 2 course completed four total aseptic technique activities, each of which was assessed by faculty using a standardized assessment tool...
February 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29695100/design-and-performance-of-a-1-ms-high-speed-vision-chip-with-3d-stacked-140-gops-column-parallel-pes-%C3%A2
#16
Atsushi Nose, Tomohiro Yamazaki, Hironobu Katayama, Shuji Uehara, Masatsugu Kobayashi, Sayaka Shida, Masaki Odahara, Kenichi Takamiya, Shizunori Matsumoto, Leo Miyashita, Yoshihiro Watanabe, Takashi Izawa, Yoshinori Muramatsu, Yoshikazu Nitta, Masatoshi Ishikawa
We have developed a high-speed vision chip using 3D stacking technology to address the increasing demand for high-speed vision chips in diverse applications. The chip comprises a 1/3.2-inch, 1.27 Mpixel, 500 fps (0.31 Mpixel, 1000 fps, 2 × 2 binning) vision chip with 3D-stacked column-parallel Analog-to-Digital Converters (ADCs) and 140 Giga Operation per Second (GOPS) programmable Single Instruction Multiple Data (SIMD) column-parallel PEs for new sensing applications. The 3D-stacked structure and column parallel processing architecture achieve high sensitivity, high resolution, and high-accuracy object positioning...
April 24, 2018: Sensors
https://www.readbyqxmd.com/read/29686977/a-prototype-exercise-empowerment-mobile-video-game-for-children-with-cancer-and-its-usability-assessment-developing-digital-empowerment-interventions-for-pediatric-diseases
#17
Carol S Bruggers, Sabrina Baranowski, Mathew Beseris, Rachel Leonard, Derek Long, Elizabeth Schulte, Ashton Shorter, Rowan Stigner, Clinton C Mason, Alisa Bedrov, Ian Pascual, Grzegorz Bulaj
Background: Medical advances continue to improve morbidity and mortality of serious pediatric diseases, including cancer, driving research addressing diminished physical and psychological quality of life in children with these chronic conditions. Empowerment enhances resilience and positively influences health, disease, and therapy understanding. We describe the development and usability assessment of a prototype Empower Stars! mobile video game grounded in behavioral and exercise theories with the purpose of coupling physical exercise with empowerment over disease in children with cancer...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29686392/spatiotemporal-control-of-dna-based-chemical-reaction-network-via-electrochemical-activation-in-microfluidics
#18
Ievgen Kurylo, Guillaume Gines, Yannick Rondelez, Yannick Coffinier, Alexis Vlandas
In recent years, DNA computing frameworks have been developed to create dynamical systems which can be used for information processing. These emerging synthetic biochemistry tools can be leveraged to gain a better understanding of fundamental biology but can also be implemented in biosensors and unconventional computing. Most of the efforts so far have focused on changing the topologies of DNA molecular networks or scaling them up. Several issues have thus received little attention and remain to be solved to turn them into real life technologies...
April 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29683660/fishing-for-drug-targets-a-focus-on-diazirine-photoaffinity-probe-synthesis
#19
James R Hill, Avril A B Robertson
Target identification is a high-priority, albeit challenging, aspect of drug discovery. Diazirine-based photoaffinity probes (PAPs) can facilitate the process by covalently capturing transient molecular interactions. This can help identify target proteins and map the ligand's interactome. Diazirine probes have even been incorporated by cellular machinery into proteins. Embarking on the synthesis of customized PAPs, containing either an aliphatic or trifluoromethyl phenyl diazirine, can be a considerable endeavor, particularly for medicinal chemists and chemical biologists new to the field...
April 23, 2018: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29676218/vaunting-the-independent-amateur-scientific-american-and-the-representation-of-lay-scientists
#20
Sean F Johnston
This paper traces how media representations encouraged enthusiasts, youth and skilled volunteers to participate actively in science and technology during the twentieth century. It assesses how distinctive discourses about scientific amateurs positioned them with respect to professionals in shifting political and cultural environments. In particular, the account assesses the seminal role of a periodical, Scientific American magazine, in shaping and championing an enduring vision of autonomous scientific enthusiasms...
April 20, 2018: Annals of Science
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