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https://www.readbyqxmd.com/read/28099182/reliability-of-the-revised-swiss-emergency-triage-scale-a-computer-simulation-study
#1
Olivier T Rutschmann, Olivier W Hugli, Christophe Marti, Olivier Grosgurin, Antoine Geissbuhler, Michel Kossovsky, Josette Simon, François P Sarasin
BACKGROUND: The Swiss Emergency Triage Scale (SETS) is a four-level emergency scale that previously showed moderate reliability and high rates of undertriage due to a lack of standardization. It was revised to better standardize the measurement and interpretation of vital signs during the triage process. OBJECTIVE: The aim of this study was to explore the inter-rater and test-retest reliability, and the rate of correct triage of the revised SETS. PATIENTS AND METHODS: Thirty clinical scenarios were evaluated twice at a 3-month interval using an interactive computerized triage simulator by 58 triage nurses at an urban teaching emergency department admitting 60 000 patients a year...
January 17, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28091839/impact-of-the-2014-2015-influenza-season-on-the-activity-of-an-academic-emergency-department
#2
Nicolas Beysard, Bertrand Yersin, Pascal Meylan, Olivier Hugli, Pierre-Nicolas Carron
The morbidity and mortality of the 2014-2015 influenza season were more important than those in previous years. We assessed the impact of the 2014-2015 influenza season on the length of stay (LOS) and workload in an academic emergency department (ED). This is a monocentric retrospective study. The database of the microbiology laboratory was used to identify influenza nasal swabs performed during the influenza seasons from 2010 to 2015. Patients admitted to the ED during these periods were identified through the administrative database and cross-checked with patients who underwent an influenza nasal swab in the ED...
January 16, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28071687/bacterial-load-of-conditioned-pressure-ulcers-is-not-a-predictor-for-early-flap-failure-in-spinal-cord-injury
#3
T Kamradt, S Klein, S Zimmermann, J Schröder-Braunstein, C H Fürstenberg, C Hensel, N Weidner, A Hug
OBJECTIVES: Pressure ulcers impose a major lifetime medical problem to patients with high-grade spinal cord injury (SCI). For patients with stages 3-4 pressure ulcers, plastic surgery is often the only remaining treatment option. Despite considerable flap failure rates of around 30%, only sparse knowledge exists on predictors for flap failure. Hence, identification of predictors for flap failures is needed. METHODS: We prospectively enrolled 38 SCI patients with stages 3-4 pressure ulcers scheduled for plastic surgery...
January 10, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28057247/clinical-implications-of-focal-intimal-disruption-in-patients-with-type%C3%A2-b%C3%A2-intramural-hematoma
#4
Sergio Moral, Hug Cuéllar, Gustavo Avegliano, Esther Ballesteros, Maria Teresa Salcedo, Ignacio Ferreira-González, David García-Dorado, Arturo Evangelista
BACKGROUND: Focal intimal disruption (FID) has been described in >20% of type B intramural hematomas (IMH), with unclear prognosis and management. OBJECTIVES: This study aimed to evaluate the short- and long-term evolution of medically treated patients with type B IMH with and without FID. METHODS: There were 107 consecutive patients with acute type B IMH were included prospectively in a multicenter protocol of clinical and imaging follow-up...
January 3, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28046661/su-f-t-208-an-efficient-planning-approach-to-posterior-fossa-tumor-bed-boosts-using-proton-pencil-beam-scanning-in-fixed-beam-room
#5
N Ju, C Chen, S Gans, E Hug, O Cahlon, S Wolden, B Chon, B Yeh, H Tsai, K Sine, D Mah
PURPOSE: A fixed-beam room could be underutilized in a multi-room proton center. We investigated the use of proton pencil beam scanning (PBS) on a fixed-beam as an alternative for posterior fossa tumor bed (PF-TB) boost treatments which were usually treating on a gantry with uniform scanning. METHODS: Five patients were treated with craniospinal irradiation (CSI, 23.4 or 36.0 Gy(RBE)) followed by a PF-TB boost to 54 Gy(RBE) with proton beams. Three PF-TB boost plans were generated for each patient: (1) a uniform scanning (US) gantry plan with 4-7 posterior fields shaped with apertures and compensators (2) a PBS plan using bi-lateral and vertex fields with a 3-mm planning organ-at-risk volume (PRV) expansion around the brainstem and (3) PBS fields using same beam arrangement but replacing the PRV with robust optimization considering a 3-mm setup uncertainty...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040254/source-distribution-and-ecotoxicological-assessment-of-multielements-in-superficial-sediments-of-a-tropical-turbid-estuarine-environment-a-multivariate-approach
#6
M J Watts, S Mitra, A L Marriott, S K Sarkar
The work examined the distribution, possible sources and ecotoxicological assessment of 51 trace elements covering 13 sampling stations in surface sediments of coastal regions of Sundarban mangrove wetland and adjacent Hugli river estuary. The element concentrations exhibited an increasing trend towards downstream of the estuary (except lanthanides) with maximum enrichment for 22 elements at Gangadharpur (Sundarban region). According to Sediment Quality Guidelines (SQGs), the concentrations of Cu, As, Cr and Cd exceeded the Effects-Range-Low values, while Ni at certain stations exceeded the Effects-Range-Medium suggesting adverse effects on the sediment-dwelling organisms...
December 28, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28033179/a-simple-hug-and-a-humble-heart
#7
David A Smith
No abstract text is available yet for this article.
January 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28019665/the-impact-of-left-ventricular-stretching-in-model-cultivations-with-neonatal-cardiomyocytes-in-a-whole-heart-bioreactor
#8
Jörn Hülsmann, Hug Aubin, Alexander Wehrmann, Artur Lichtenberg, Payam Akhyari
Here, we investigate the impact of integrated three-dimensional (3D) left ventricular (LV) stretching on myocardial maturation in a whole-heart bioreactor setting. Therefore, decellularized rat hearts were selectively repopulated with rodent neonatal cardiomyocytes (5•10(6) cells per heart) and cultured over 5 d. Continuous medium perfusion was maintained through the coronary artery system in a customized whole-heart bioreactor system with or without integrated biomechanical stimulation of LV. 3D repopulation effectiveness and cellular vitality were evaluated by repetitive metabolic WST-1 assays and 3D confocal microscopy analysis through fluorescent staining, also assessing cellular organization...
December 26, 2016: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28000312/motor-adaptations-to-unilateral-quadriceps-fatigue-during-a-bilateral-pedaling-task
#9
N-P Brøchner Nielsen, F Hug, A Guével, V Fohanno, J Lardy, S Dorel
This study was designed to investigate how motor coordination adapts to unilateral fatigue of the quadriceps during a constant-load bilateral pedaling task. We first hypothesized that this local fatigue would not be compensated within the fatigued muscles leading to a decreased knee extension power. Then, we aimed to determine whether this decrease would be compensated by between-joints compensations within the ipsilateral leg and/or an increased contribution of the contralateral leg. Fifteen healthy volunteers were tested during pedaling at 350 W before and after a fatigue protocol consisting of 15 minutes of electromyostimulation on the quadriceps muscle...
December 20, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/27990024/integrating-the-dimensions-of-ngss-within-a-collaborative-board-game-about-honey-bees
#10
Hillary Lauren, Claudia Lutz, Robert C Wallon, Barbara Hug
The current reform in U.S. science education calls for the integration of three dimensions of science learning in classroom teaching and learning: Science and Engineering Practices, Crosscutting Concepts, and Disciplinary Core Ideas. While the Next Generation Science Standards provide flexibility in how curriculum and instruction are structured to meet learning goals, there are few examples of existing curricula that portray the integration of these dimensions as "three-dimensional learning." Here, we describe a collaborative board game about honey bees that incorporates scientific evidence on how genetic and environmental factors influence variations of traits and social behavior and requires students to collaboratively examine and use a system model...
November 2016: American Biology Teacher
https://www.readbyqxmd.com/read/27990023/the-bio-bay-game-three-dimensional-learning-of-biomagnification
#11
Chandana Jasti, Hillary Lauren, Robert C Wallon, Barbara Hug
Pressing concerns about sustainability and the state of the environment amplify the need to teach students about the connections between ecosystem health, toxicology, and human health. Additionally, the Next Generation Science Standards call for three-dimensional science learning, which integrates disciplinary core ideas, scientific practices, and crosscutting concepts. The Bio Bay Game is a way to teach students about the biomagnification of toxicants across trophic levels while engaging them in three-dimensional learning...
November 2016: American Biology Teacher
https://www.readbyqxmd.com/read/27979871/thornburg-cd-files-ba-luo-z-et-al-impact-of-hydroxyurea-on-clinical-events-in-the-baby-hug-trial-blood-2012-120-22-4304-4310
#12
(no author information available yet)
No abstract text is available yet for this article.
December 15, 2016: Blood
https://www.readbyqxmd.com/read/27976967/the-ethics-of-withdrawal-the-case-of-follow-up-from-first-in-human-clinical-trials
#13
Kristina Hug, Mats Johansson
This paper aims to analyze whether patients should be allowed to veto research-related use of medical data collected during routine follow-ups after their withdrawal from first-in-human clinical trials. Forms of withdrawal are identified and it is argued that the right to withdraw might be limited to some of these. The paper concludes that if veto right is denied, then: the research participant should be informed about the potential use of his/her follow-up data in case of his/her withdrawal and consent to it; follow-up should not be initiated for research purposes; compulsory use of follow-up data should imply the use of data anyway collected, requiring no additional effort from the patient; and before deciding about the veto right, investigation of concerned patients' value preferences is needed...
January 2017: Regenerative Medicine
https://www.readbyqxmd.com/read/27966225/parasympathetic-withdrawal-increases-heart-rate-after-two-weeks-at-3-454%C3%A2-m-altitude
#14
Christoph Siebenmann, Peter Rasmussen, Mike Hug, Stefanie Keiser, Daniela Flück, James P Fisher, Matthias P Hilty, Marco Maggiorini, Carsten Lundby
Chronic hypoxia increases resting heart rate (HR), but the underlying mechanism remains incompletely understood. We investigated the relative contributions of the sympathetic and parasympathetic nervous systems, along with potential non-autonomic mechanisms, by individual and combined pharmacological inhibition of muscarinic and/or β-adrenergic receptors. In seven healthy lowlanders, resting HR was determined at sea level (SL) and after 15-18 days of exposure to 3,454 m high altitude (HA) without drug intervention (CONT) as well as after intravenous administration of either propranolol (PROP), glycopyrrolate (GLYC), or PROP and GLYC in combination (PROP+GLYC)...
December 14, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27923635/novel-application-of-a-radial-water-tread-maze-can-distinguish-cognitive-deficits-in-mice-with-traumatic-brain-injury
#15
Marcella M Cline, Josh Yumul, Lisa Hysa, Dalia Murra, Gregory G Garwin, David G Cook, Warren Ladiges, Satoshi Minoshima, Donna J Cross
INTRODUCTION: The use of forced-swim, rat-validated cognition tests in mouse models of Traumatic Brain Injury (TBI) raises methodological concerns; such models are vulnerable to a number of confounding factors including impaired motor function and stress-induced non-compliance (failure to swim). This study evaluated the ability of a Radial Water Tread (RWT) maze, designed specifically for mice, that requires no swimming to distinguish mice with controlled cortical impact (CCI) induced TBI and Sham controls...
December 3, 2016: Brain Research
https://www.readbyqxmd.com/read/27913924/shear-wave-elastography-reveals-different-degrees-of-passive-and-active-stiffness-of-the-neck-extensor-muscles
#16
Angela V Dieterich, Ricardo J Andrade, Guillaume Le Sant, Deborah Falla, Frank Petzke, François Hug, Antoine Nordez
PURPOSE: The neck extensor muscles contribute to spinal support and posture while performing head and neck motion. Muscle stiffness relates to passive elasticity (support) and active tensioning (posture and movement) of muscle. It was hypothesized that support and motion requirements are reflected in the distribution of stiffness between superficial and deep neck extensor muscles. METHODS: In ten healthy participants, shear modulus (stiffness) of five neck extensor muscles was determined in prone at rest and during isometric head lift at three intensities using shear wave elastography...
December 2, 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27912037/avalanche-accidents-causing-fatalities-are-they-any-different-in-the-summer
#17
Mathieu Pasquier, Olivier Hugli, Alexandre Kottmann, Frank Techel
: Pasquier, Mathieu, Olivier Hugli, Alexandre Kottmann, and Frank Techel. Avalanche accidents causing fatalities: are they any different in the summer? High Alt Med Biol. 16:000-000, 2016. AIMS: This retrospective study investigated the epidemiology of summer avalanche accidents that occurred in Switzerland and caused at least one fatality between 1984 and 2014. Summer avalanche accidents were defined as those that occurred between June 1st and October 31st. RESULTS: Summer avalanches caused 21 (4%) of the 482 avalanches with at least one fatality occurring during the study period, and 40 (6%) of the 655 fatalities...
December 2, 2016: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27871206/brucellosis-and-thrombosis-of-the-inferior-vena-cava
#18
Kristina Rüegger, Philip Tarr, Konstantinos Karatolios, Jörg Humburg, Rolf Hügli, Christina Jeanneret
We describe the case of a 23-year old woman with a newly diagnosed thrombosis of the inferior vena cava associated with a Brucella melitensis infection. We suggest possible mechanisms leading to brucellosis-associated venous thrombosis and review 14 previously reported cases.
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November 22, 2016: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27867964/an-electromechanical-hug-for-the-failing-heart
#19
COMMENT
Ron Feiner, Tal Dvir
No abstract text is available yet for this article.
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27866089/absence-of-epithelial-atypia-in-b3-lesions-of-the-breast-is-associated-with-decreased-risk-for-malignancy
#20
Sebastian Mayer, Gian Kayser, Gerta Rücker, Diana Bögner, Marc Hirschfeld, Christiane Hug, Elmar Stickeler, Gerald Gitsch, Thalia Erbes
INTRODUCTION: Lesions of uncertain malignant potential (B3) represent a heterogeneous group with an overall risk for malignancy of 9.85-35.1% after total resection. Positive predictive values (PPV) for malignancy vary depending on B3 subtype. The aim of this study was to evaluate the PPV for malignancy in B3 lesions and to determine the clinical significance of atypia-dependent sub-classification (a = without epithelial atypia; b = with epithelial atypia) of B3 into B3a and B3b and papillary lesions (PL) in PLa and PLb...
February 2017: Breast: Official Journal of the European Society of Mastology
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