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https://www.readbyqxmd.com/read/29327169/passive-stiffness-of-monoarticular-lower-leg-muscles-is-influenced-by-knee-joint-angle
#1
Filiz Ateş, Ricardo J Andrade, Sandro R Freitas, François Hug, Lilian Lacourpaille, Raphael Gross, Can A Yucesoy, Antoine Nordez
PURPOSE: While several studies demonstrated the occurrence of intermuscular mechanical interactions, the physiological significance of these interactions remains a matter of debate. The purpose of this study was to quantify the localized changes in the shear modulus of the gastrocnemius lateralis (GL), monoarticular dorsi- and plantar-flexor muscles induced by a change in knee angle. METHOD: Participants underwent slow passive ankle rotations at the following two knee positions: knee flexed at 90° and knee fully extended...
January 11, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29306667/arsenate-co-precipitation-with-fe-ii-oxidation-products-and-retention-or-release-during-precipitate-aging
#2
Anna-Caterina Senn, Stephan J Hug, Ralf Kaegi, Janet G Hering, Andreas Voegelin
The co-precipitation of arsenate (As(V)) with Fe(III)-precipitates is of great importance in water treatment and critically affects the fate of As in environmental systems. We studied the effects of dissolved phosphate (P; 0-1 mM), silicate (Si; 0 or 0.5 mM) and Ca (0, 0.5 and 4 mM) on the sequestration of 7 μM As(V) by Fe(III)-precipitates formed by the oxidation of 0.5 mM Fe(II) in aerated bicarbonate-buffered solutions with an initial pH of 7.0 as well as the retention or release of As(V) after precipitate aging for 30 d at 40 °C...
December 19, 2017: Water Research
https://www.readbyqxmd.com/read/29297335/mining-significant-high-utility-gene-regulation-sequential-patterns
#3
Morteza Zihayat, Heidar Davoudi, Aijun An
BACKGROUND: Mining frequent gene regulation sequential patterns in time course microarray datasets is an important mining task in bioinformatics. Although finding such patterns are of paramount important for studying a disease, most existing work do not consider gene-disease association during gene regulation sequential pattern discovery. Moreover, they consider more absent/existence effects of genes during the mining process than taking the degrees of genes expression into account. Consequently, such techniques discover too many patterns which may not represent important information to biologists to investigate the relationships between the disease and underlying reasons hidden in gene regulation sequences...
December 14, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/29296035/grid-block-design-based-on-monte-carlo-simulated-dosimetry-the-linear-quadratic-and-hug-kellerer-radiobiological-models
#4
Somayeh Gholami, Hassan Ali Nedaie, Francesco Longo, Mohammad Reza Ay, Sharifeh A Dini, Ali S Meigooni
Purpose: The clinical efficacy of Grid therapy has been examined by several investigators. In this project, the hole diameter and hole spacing in Grid blocks were examined to determine the optimum parameters that give a therapeutic advantage. Methods: The evaluations were performed using Monte Carlo (MC) simulation and commonly used radiobiological models. The Geant4 MC code was used to simulate the dose distributions for 25 different Grid blocks with different hole diameters and center-to-center spacing...
October 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/29249218/direct-costs-of-a-contact-isolation-day-a-prospective-cost-analysis-at-a-swiss-university-hospital
#5
Jan A Roth, Claudia Hornung-Winter, Isabel Radicke, Balthasar L Hug, Monika Biedert, Christian Abshagen, Manuel Battegay, Andreas F Widmer
We prospectively evaluated direct costs of contact precautions using on-site observation. Additional mean costs per patient day were calculated for extra materials used, increased workload, and one-off isolation activities. The cost of contact precautions was $158.90 (95% confidence interval, $124.90‒$192.80) per patient day. Infect Control Hosp Epidemiol 2017;1-3.
December 18, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29248875/development-and-psychometric-validation-of-a-shorter-version-of-the-breast-cancer-treatment-outcome-scale-bctos-12
#6
André Hennigs, Jörg Heil, Annette Wagner, Michelle Rath, Helfried Moosbrugger, Augustin Kelava, Michael Golatta, Sarah Hug, Fabian Riedel, Geraldine Rauch, Manuel Feißt
OBJECTIVES: Aesthetic and functional outcomes after oncoplastic breast-conserving surgery (BCS) are directly related to the patients' quality of life (QoL). The Breast Cancer Treatment Outcome Scale (BCTOS) is a validated but burdensome questionnaire for the assessment of these outcomes. The aim of the study was to strengthen and focus the BCTOS instrument by reducing the number of items and subscales without loss of information and validity. METHODS: This study used a dataset of 871 patients with stage 0 - III breast cancer, from a prospective cohort study, who underwent BCS...
December 14, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29225161/self-efficacy-and-pressure-ulcer-prevention-after-spinal-cord-injury-results-from-a-nationwide-community-survey-in-switzerland-swisci
#7
Kerstin Hug, Caroline Stumm, Isabelle Debecker, Carolina Saskia Fellinghauer, Claudio Peter, Magret Hund-Georgiadis
BACKGROUND: Pressure ulcers (PUs) are a common and severe health condition in persons with spinal cord injury (SCI). Skin-care strategies for PU prevention are usually provided during first rehabilitation. However, individuals with SCI often do not perform these strategies continuously, especially after discharge. The influence of psychological factors such as general self-efficacy (GSE) on the performance of PU prevention behavior has not yet been sufficiently explored. OBJECTIVE: To investigate if persons with higher levels of GSE are more likely to perform skin-care strategies for PU prevention regularly...
December 7, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29216776/the-hand-injury-caused-by-cutting-avocado-in-18-patients
#8
Martina Greminger, Itai Pasternak, Urs Hug
No abstract text is available yet for this article.
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29216699/-diagnostic-value-of-a-predictive-model-for-complete-ruptures-of-the-rotator-cuff-associated-to-subacromial-impingement
#9
I R Águila-Ledesma, J L Córdova-Fonseca, O Medina-Pontaza, D A Núñez-Gómez, C Calvache-García, J M Pérez-Atanasio, R Torres-González
Pathology related to the rotator cuff remains among the most prevalent musculoskeletal diseases. There is an increasing need for imaging studies (MRI, US, arthroscopy) to test the diagnostic performance of the medical history and physical examination. OBJECTIVE: To prove the diagnostic value of a clinical-radiographic predictive model to find complete ruptures of the rotator cuff. MATERIAL AND METHODS: Descriptive, observational, prospective, transversal and analytical study...
May 2017: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/29209634/the-vilkki-procedure-as-an-emergency-treatment-in-an-apocalyptical-hand-injury-a-case-report-and-first-description
#10
Dominique Merky, Katarina Wishart, Urs Hug, Elmar Fritsche
We describe a young man who suffered a severe mutilating injury of the hand and forearm while working as a cheesemaker. He underwent a complex reconstruction of his right adominant hand including a heterotopic thumb replantation into the distal radius and combined with an emergency flow-through anterolateral thigh flap.
2017: Case Reports in Plastic Surgery & Hand Surgery
https://www.readbyqxmd.com/read/29202173/dcc-ntn1-complex-mutations-in-patients-with-congenital-hypogonadotropic-hypogonadism-impair-gnrh-neuron-development
#11
Justine Bouilly, Andrea Messina, Georgios Papadakis, Daniele Cassatella, Cheng Xu, James S Acierno, Brooke Tata, Gerasimos Sykiotis, Sara Santini, Yisrael Sidis, Eglantine Elowe-Gruau, Franziska Phan-Hug, Michael Hauschild, Pierre-Marc Bouloux, Richard Quinton, Mariarosaria Lang-Muritano, Lucie Favre, Laura Marino, Paolo Giacobini, Andrew A Dwyer, Nicolas J Niederländer, Nelly Pitteloud
Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disease characterized by absent puberty and infertility due to GnRH deficiency, and is often associated with anosmia (Kallmann syndrome, KS). The genetic etiology of CHH is heterogeneous, and more than 30 genes have been implicated in approximately 50% of patients with CHH. We hypothesized that genes encoding axon-guidance proteins containing fibronectin type-III (FN3) domains (similar to ANOS1, the first gene associated with KS), are mutated in CHH...
November 30, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29193343/response-to-considerations-on-achilles-and-patellar-tendinopathy-display-opposite-changes-in-elastic-properties
#12
Brooke Kaye Coombes, Kylie Tucker, Bill Vicenzino, Viana Vuvan, Rebecca Mellor, Luke Heales, Antoine Nordez, François Hug
We thank Wu (2017) and the editors for the opportunity to provide greater discussion on the association of tendon shear wave velocity (SWV) with potentially important covariates including sex and age. We would like to first clarify that we did not directly compare the Achilles and patellar tendinopathy groups. Instead, the (most) affected tendon from each tendinopathy group was compared with a matched tendon from the healthy control group. This article is protected by copyright. All rights reserved.
November 28, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29192619/tinnitus-medial-olivocochlear-system-and-music-exposure-in-adolescents
#13
María Hinalaf, Ana L Maggi, Mercedes X Hüg, Pablo Kogan, Jorge Pérez Villalobo, Ester C Biassoni
INTRODUCTION: The most common cause of tinnitus is the exposure to noise; in the case of adolescents, music is the main sound source they are exposed to. Currently, one of the hypotheses about the genesis of tinnitus is related to the deterioration in the functioning of the medial olivocochlear system (MOCS). AIM: The aim of this study was to determine the presence or absence of tinnitus in adolescents with normal hearing and to relate it to: (a) the functioning of the MOCS, by the contralateral suppression of the transient evoked otoacoustic emissions (TEOAEs) and (b) the musical general exposure (MGE)...
March 2017: Noise & Health
https://www.readbyqxmd.com/read/29188481/using-case-management-in-a-universal-health-coverage-system-to-improve-quality-of-life-of-frequent-emergency-department-users-a-randomized-controlled-trial
#14
Katia Iglesias, Stéphanie Baggio, Karine Moschetti, Jean-Blaise Wasserfallen, Olivier Hugli, Jean-Bernard Daeppen, Bernard Burnand, Patrick Bodenmann
PURPOSE: Frequent Emergency Department users are likely to experience poor quality of life (QOL). Case management interventions are efficient in responding to the complex needs of this population, but their effects on QOL have not been tested yet. Therefore, the aim of our study was to examine to what extent a case management intervention improved frequent Emergency Department users' QOL in a universal health coverage system. METHODS: Data were part of a randomized controlled trial designed to improve frequent Emergency Department users' QOL at the Lausanne University Hospital, Switzerland...
November 29, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29147849/heterogeneity-of-passive-elastic-properties-within-the-quadriceps-femoris-muscle-tendon-unit
#15
Brooke K Coombes, Brandon Ziegenfuss, Michael David, Rohitha Badya, Wolbert van den Hoorn, François Hug, Kylie Tucker
PURPOSE: The purpose of this study was to compare regional elastic properties between anterior and posterior regions of the patellar tendon, and individual quadriceps muscles, over a range of knee flexion angles. METHODS: An isokinetic dynamometer passively positioned the non-dominant knee of 19 young, healthy participants, at 25°, 40°, 55°, 70° and 85° flexion. Shear wave velocity (SWV, an index of tissue elasticity) was measured using ultrasound shear wave elastography in a relaxed (passive) state, confirmed by electromyography...
November 17, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29143461/do-animal-exhibitors-support-and-follow-recommendations-to-prevent-transmission-of-variant-influenza-at-agricultural-fairs-a-survey-of-animal-exhibitor-households-after-a-variant-influenza-virus-outbreak-in-michigan
#16
R J Stewart, J Rossow, J T Conover, E E Lobelo, S Eckel, K Signs, M G Stobierski, S C Trock, A M Fry, S J Olsen, M Biggerstaff
Influenza A viruses circulate in swine and can spread rapidly among swine when housed in close proximity, such as at agricultural fairs. Youth who have close and prolonged contact with influenza-infected swine at agricultural fairs may be at increased risk of acquiring influenza virus infection from swine. Animal and human health officials have issued written measures to minimize influenza transmission at agricultural exhibitions; however, there is little information on the knowledge, attitudes, and practice (KAP) of these measures among animal exhibitors...
November 16, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29142387/fast-hugs-bid-modified-mnemonic-for-surgical-patient
#17
Abhijit S Nair, Vibhavari Milind Naik, Basanth Kumar Rayani
No abstract text is available yet for this article.
October 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29133793/binding-to-smn2-pre-mrna-protein-complex-elicits-specificity-for-small-molecule-splicing-modifiers
#18
Manaswini Sivaramakrishnan, Kathleen D McCarthy, Sébastien Campagne, Sylwia Huber, Sonja Meier, Angélique Augustin, Tobias Heckel, Hélène Meistermann, Melanie N Hug, Pascale Birrer, Ahmed Moursy, Sarah Khawaja, Roland Schmucki, Nikos Berntenis, Nicolas Giroud, Sabrina Golling, Manuel Tzouros, Balazs Banfai, Gonzalo Duran-Pacheco, Jens Lamerz, Ying Hsiu Liu, Thomas Luebbers, Hasane Ratni, Martin Ebeling, Antoine Cléry, Sergey Paushkin, Adrian R Krainer, Frédéric H-T Allain, Friedrich Metzger
Small molecule splicing modifiers have been previously described that target the general splicing machinery and thus have low specificity for individual genes. Several potent molecules correcting the splicing deficit of the SMN2 (survival of motor neuron 2) gene have been identified and these molecules are moving towards a potential therapy for spinal muscular atrophy (SMA). Here by using a combination of RNA splicing, transcription, and protein chemistry techniques, we show that these molecules directly bind to two distinct sites of the SMN2 pre-mRNA, thereby stabilizing a yet unidentified ribonucleoprotein (RNP) complex that is critical to the specificity of these small molecules for SMN2 over other genes...
November 14, 2017: Nature Communications
https://www.readbyqxmd.com/read/29128860/evaluation-of-different-dose-rate-combinations-of-ketamine-romifidine-and-azaperone-for-castration-of-3-4-and-5-6-weeks-old-piglets
#19
V H Cap, P J Hug, T Echtermann, S Von Ah, I Nussbaumer, F Janett, R Bettschart-Wolfensberger
In this study dose rate combinations of ketamine, azaperone and romifidine were tested in 3-4 (G3-4) and 5-6 weeks (G5-6) old piglets according to a dose rate decision tree (DRT) to provide calm anaesthesia induction, reaction-free anaesthesia for castration and smooth recovery within 2 hours. When a combination failed to meet those criteria in 2 piglets, the next dosage of the DRT was tested. In G3-4 four combinations were tested in 14 piglets with dose rates of 10-20 mg/kg ketamine, 3 mg/kg azaperone and 0...
November 2017: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29118727/huggable-communication-medium-maintains-level-of-trust-during-conversation-game
#20
Hideyuki Takahashi, Midori Ban, Hirotaka Osawa, Junya Nakanishi, Hidenobu Sumioka, Hiroshi Ishiguro
There have been several attempts in recent years to develop a remote communication device using sensory modalities other than speech that would induce a user's positive experience with his/her conversation partner. Specifically, Hugvie is a human-shaped pillow as well as a remote communication device enabling users to combine a hugging experience with telecommunication to improve the quality of remote communication. The present research is based on the hypothesis that using Hugvie maintains users' level of trust toward their conversation partners in situations prone to suspicion...
2017: Frontiers in Psychology
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