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https://www.readbyqxmd.com/read/27893838/performance-evaluation-of-malaria-microscopists-at-defense-health-facilities-in-addis-ababa-and-its-surrounding-areas-ethiopia
#1
Tigist Yitbarek, Desalegn Nega, Geremew Tasew, Bineyam Taye, Kassu Desta
BACKGROUND: Blood film microscopy is the gold standard approach for malaria diagnosis, and preferred method for routine patient diagnosis in health facilities. However, the inability of laboratory professionals to correctly detect and identify malaria parasites microscopically leads to an inappropriate administration of anti-malarial drugs to the patients and incorrect findings in research areas. This study was carried out to evaluate the performance of laboratory professionals in malaria diagnosis in health facilities under the Defense Health Main Department in Addis Ababa and its surroundings, Ethiopia...
2016: PloS One
https://www.readbyqxmd.com/read/27891232/prevalence-of-transfusion-transmissible-infections-in-blood-donors-of-pakistan
#2
Aisha Arshad, Munira Borhany, Nida Anwar, Imran Naseer, Rehan Ansari, Samson Boota, Naveena Fatima, Mustansir Zaidi, Tahir Shamsi
BACKGROUND: Transfusion-transmitted infections threaten the safety of patients requiring blood transfusion, which in turn imposes serious challenges for the availability of safe blood products that are still affordable in health care systems with limited resources. The aim of the study was to determine the prevalence of transfusion-transmitted infections in blood donors and to evaluate the demographic characteristics of reactive and non-reactive blood donors. METHODS: A prospective cohort study was conducted at our institute in Karachi, Pakistan...
2016: BMC Hematology
https://www.readbyqxmd.com/read/27889443/the-application-of-silicon-sol-gel-technology-to-forensic-blood-substitute-development-mimicking-aspects-of-whole-human-blood-rheology
#3
Theresa Stotesbury, Mike Illes, Paul Wilson, Andrew J Vreugdenhil
Solution-gelation chemistry has promising applications in forensic synthetic blood substitute development. This research offers a silicon-based sol-gel approach to creating stable materials that share similar rheological properties to that of whole human blood samples. Room temperature, high water content, silicon sol-gels were created using the organosilane precursors 3-glycidoxypropyltrimethoxysilane and tetraethylorthosilicate along with various concentrations of filler and pigment. Shear-thinning non-Newtonian properties were observed within most formulations of the presented materials...
November 15, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27876998/occurrence-of-knemidokoptes-mutans-and-laminosioptes-cysticola-in-backyard-poultry-in-india
#4
C Sreedevi, P Ramesh, P Mala Kondaiah, N Lakshmi Rani, M Abhishek
Birds reared in backyard poultry farming system are more prone to parasitic infestation resulting in economic losses to rural community. The present study reports occurrence of Knemidokoptes mutans and Laminosioptes cysticola mites in a male Aseel bird. Clinical signs observed in the affected bird include hyperkeratosis with whitish film layer on shank and hock region of legs. Focal areas of sloughing of skin with oozing of blood were also observed on the back and on the legs. Examination of skin scrapings from the affected sites revealed different developmental stages of Knemidokoptes mutans and Laminosioptes cysticola mites...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27871387/mediator-free-interaction-of-glucose-oxidase-as-model-enzyme-for-immobilization-with-al-doped-and-undoped-zno-thin-films-laser-deposited-on-polycarbonate-supports
#5
Fidal V T K P, Saikumar Inguva, Satheesh Krishnamurthy, Enrico Marsili, Jean-Paul Mosnier, Chandra T S
Al doped and undoped ZnO thin films were deposited by pulsed-laser deposition on polycarbonate sheets. The films were characterized by optical transmission, Hall effect measurement, XRD and SEM. Optical transmission and surface reflectometry studies showed good transparency with thicknesses ∼100nm and surface roughness of 10nm. Hall effect measurements showed that the sheet carrier concentration was -1.44×10(15)cm(-2) for AZO and -6×10(14)cm(-2) for ZnO. The films were then modified by drop-casting glucose oxidase (GOx) without the use of any mediators...
January 2017: Enzyme and Microbial Technology
https://www.readbyqxmd.com/read/27869855/analytical-and-simulation-results-of-a-triple-micro-whispering-gallery-mode-probe-system-for-a-3d-blood-flow-rate-sensor
#6
Prateep Phatharacorn, Surasak Chiangga, Preecha Yupapin
The whispering gallery mode (WGM) is generated by light propagating within a nonlinear micro-ring resonator, which is modeled and made by an InGaAsP/InP material, and called a Panda ring resonator. An imaging probe can also be formed by the micro-conjugate mirror function for the appropriate Panda ring parameter control. The 3D WGM probe can be generated and used for a 3D sensor head and imaging probe. The analytical details and simulation results are given, in which the simulation results are obtained by using the MATLAB and Optiwave programs...
November 20, 2016: Applied Optics
https://www.readbyqxmd.com/read/27867245/diamond-coated-artificial-cardiovascular-devices
#7
Hongjun Zeng, Robert Jarvik, Grace Catausan, Nicolaie Moldovan, John Carlisle
Ultrananocrystalline diamond (UNCD), an extremely smooth, low cost diamond coating was successfully developed herein for antithrombogenic application which requires high biocompatibility, low wear, low friction, and chemical inertness. The substrate materials utilized in the Jarvik 2000 ventricular assist device (VAD), silicon carbide and titanium alloy, provide an excellent substrate match for UNCD integration. The paper addresses the development of medical-quality UNCD films to significantly improve the knowledge base regarding the defect mechanisms of UNCD films, to reduce or eliminate known wear-inducing imperfections in the film, and to thoroughly characterize and test the films as well as assembled UNCD-coated VADs...
September 25, 2016: Surface & Coatings Technology
https://www.readbyqxmd.com/read/27861860/oral-toxicity-of-cold-plasma-treated-edible-films-for-food-coating
#8
Sung Hee Han, Hyung Joo Suh, Ki Bae Hong, Su Yeon Kim, Sea C Min
No prior research has investigated whether the cold plasma treatment (CPT) resulted in the formation of toxic compounds. Therefore, this study carried out the experiment to check the safety of edible films treated with cold plasma by examining their acute and subacute oral toxicity in a rat model. Single-dose acute (5000 mg/kg body weight) and 14-d subacute (1000 mg/kg body weight/day) oral toxicity of cold plasma-treated edible films was assessed for male and female Sprague-Dawley (SD) rats. Rats administered 5000 mg/kg of edible film did not show the signs of acute toxicity or death after 14 d of observation...
November 8, 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27843316/nanomicelles-loaded-with-doxorubicin-and-curcumin-for-alleviating-multidrug-resistance-in-lung-cancer
#9
Yue Gu, Jing Li, Yang Li, Lei Song, Dan Li, Liping Peng, Ying Wan, Shucheng Hua
PURPOSE: A new type of polymeric micelle (PM) was assembled using a polyethylene glycol (PEG)-linked (PEGylated) amphiphilic copolymer and d-tocopheryl PEG1000 succinate (TPGS1000). The micelles were used to deliver doxorubicin (DOX) and curcumin (CUR) for alleviating multidrug resistance (MDR) in lung cancer cells while enhancing the therapeutic efficacy of DOX. METHODS: Micelles loaded with DOX and CUR were assembled using a film-forming technique. Micelles were used to treat A549/Adr cells to find out whether micelles had the ability to reverse the MDR of A549/Adr cells...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27843312/formulation-characterization-and-tissue-distribution-of-a-novel-ph-sensitive-long-circulating-liposome-based-theranostic-suitable-for-molecular-imaging-and-drug-delivery
#10
Yin Duan, Lihui Wei, Julia Petryk, Terrence D Ruddy
PURPOSE: When designing liposome formulas for treatment and diagnostic purposes, two of the most common challenges are 1) the lack of a specific release mechanism for the encapsulated contents and 2) a short circulation time due to poor resistance to biological fluids. This study aimed to create a liposome formula with prolonged in vivo longevity and pH-sensitivity for cytoplasmic drug delivery. MATERIALS AND METHODS: Liposomal particles were generated using hydrogenated soy (HS) phosphatidylcholine, cholesteryl hemisuccinate (CHEM), polyethylene glycol (PEG) and diethylenetriaminepentaacetic acid-modified phosphatidylethanolamine with film hydration and extrusion methods...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27829743/role-of-plasma-rich-fibrin-in-oral-surgery
#11
REVIEW
K Retna Kumar, K Genmorgan, S M Abdul Rahman, M Alaguvel Rajan, T Arul Kumar, V Srinivas Prasad
Platelet-rich fibrin (PRF) is a fibrin meshwork, in which platelet cytokines, growth factors, and cells are entrapped and discharged after a period and can serve as a resorbable film. PRF is the next generation of platelet concentrates equipped to improve arrangement without biochemical blood handling; PRF is an evolution of the fibrin adhesive, which is widely used in the oral surgery. The guidelines of this innovation depend on concentrating platelets and growth factors in a plasma medium, and initiating them in a fibrin gel, keeping in mind the end goal to enhance the healing of wounds...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/27826893/comparison-of-time-domain-spectral-domain-and-swept-source-oct-in-evaluating-aqueous-cells-in-vitro
#12
Meng Li, Huaizhou Wang, Yue Liu, Xifang Zhang, Ningli Wang
Different optical coherence tomography (OCT), both time-domain OCT and spectral-domain OCT, has been used to evaluate anterior chamber cells in previous studies. Recently, commercial swept-source OCT was available. The comparison among three kinds of OCTs have not been done before. Here, we compared their feasibility in discerning aqueous cells in vitro. The peripheral blood was diluted to eight different cell concentrations and was packed into plastic-film bag. Each sample was tested using different scan modes of three OCTs...
November 4, 2016: Science China. Life Sciences
https://www.readbyqxmd.com/read/27816406/two-layer-sheet-of-gelatin-a-new-topical-hemostatic-agent
#13
Toshitaka Takagi, Hiroyuki Tsujimoto, Hiroko Torii, Yuki Ozamoto, Akeo Hagiwara
BACKGROUND/OBJECTIVE: Uncontrolled surgical bleeding is associated with increased morbidity, mortality, and hospital cost. Topical hemostatic agents available today have problems controlling hemostatic effects; furthermore, their handling is difficult and they are unsafe. METHODS: We devised a new hemostatic agent comprising gelatin sponge and film designed to be applied to the bleeding site, thereby creating a topical hemostatic agent made of gelatin alone. The gelatin was prepared by alkali treatment to eliminate viral activity...
November 2, 2016: Asian Journal of Surgery
https://www.readbyqxmd.com/read/27811305/ammecr1-a-single-point-mutation-causes-developmental-delay-midface-hypoplasia-and-elliptocytosis
#14
Gaia Andreoletti, Eleanor G Seaby, Jennifer M Dewing, Ita O'Kelly, Katherine Lachlan, Rodney D Gilbert, Sarah Ennis
BACKGROUND: Deletions in the Xq22.3-Xq23 region, inclusive of COL4A5, have been associated with a contiguous gene deletion syndrome characterised by Alport syndrome with intellectual disability (Mental retardation), Midface hypoplasia and Elliptocytosis (AMME). The extrarenal biological and clinical significance of neighbouring genes to the Alport locus has been largely speculative. We sought to discover a genetic cause for two half-brothers presenting with nephrocalcinosis, early speech and language delay and midface hypoplasia with submucous cleft palate and bifid uvula...
November 3, 2016: Journal of Medical Genetics
https://www.readbyqxmd.com/read/27807618/molecular-and-morphological-characterization-of-a-haemogregarine-in-the-alligator-snapping-turtle-macrochelys-temminckii-testudines-chelydridae
#15
Amer Rasool Alhaboubi, Dana A Pollard, Patricia J Holman
A severely underweight alligator snapping turtle Macrochelys temminckii Troost in Harlan, 1835, was found near Tyler, Texas, and taken to the Caldwell Zoo. Blood films were submitted to Texas A&M University, College Station, Texas, for morphological and molecular identification of haemogregarine-like inclusions in the red blood cells. Intraerythrocytic Haemogregarina sp. forms were found on microscopic examination at a parasitemia of <1 %. The morphology and morphometric data for the forms indicate similarity to Haemogregarina macrochelysi n...
November 2, 2016: Parasitology Research
https://www.readbyqxmd.com/read/27803011/chronic-lead-poisoning-in-an-iranian-opium-smoker-resident-in-london
#16
Alex Azizi, Katie Ferguson, Sam Dluzewski, Tajammul Hussain, Martin Klein
A 46-year-old man of Iranian origin presented with a 4-day history of colicky abdominal pain and absolute constipation on a background of several weeks of irritability and malaise. He had smoked 10 g of opium per week for a year and a half. On examination, he had diffuse abdominal tenderness and faecal loading. This was cleared, but the abdominal pain, nausea and vomiting persisted. He had extravascular haemolytic anaemia with punctate basophilic stippling on blood film. The patient's serum lead concentration was substantially elevated and he perhaps demonstrated Burton's line...
November 1, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27800099/prevalence-of-anaemia-among-quranic-school-khalawi-students-heiran-in-wad-el-magboul-village-rural-rufaa-gezira-state-central-sudan-a-cross-sectional-study
#17
Mohammed Saeed Elsamani Eltayeb, Awad Eseed Elsaeed, Ahmed Abdalla Mohamedani, Abbas Abdalrahman Assayed
INTRODUCTION: This is a cross sectional descriptive community-based study. The aim was to assess the prevalence of anaemia among quranic schoolchildren in khalawi Wad EL Magboul village, rural Rufaa, Gezira State, central Sudan. METHODS: A sample of 180 male participants were included in the study. Informed consent was obtained. Venous blood samples were obtained to measure the hematological parameters and blood films for malaria parasites. Urine and stool analyses were also done...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27788243/submicroscopic-and-asymptomatic-plasmodium-parasitaemia-associated-with-significant-risk-of-anaemia-in-papua-indonesia
#18
Zuleima Pava, Faustina H Burdam, Irene Handayuni, Leily Trianty, Retno A S Utami, Yusrifar Kharisma Tirta, Enny Kenangalem, Daniel Lampah, Andreas Kusuma, Grennady Wirjanata, Steven Kho, Julie A Simpson, Sarah Auburn, Nicholas M Douglas, Rintis Noviyanti, Nicholas M Anstey, Jeanne R Poespoprodjo, Jutta Marfurt, Ric N Price
Submicroscopic Plasmodium infections are an important parasite reservoir, but their clinical relevance is poorly defined. A cross-sectional household survey was conducted in southern Papua, Indonesia, using cluster random sampling. Data were recorded using a standardized questionnaire. Blood samples were collected for haemoglobin measurement. Plasmodium parasitaemia was determined by blood film microscopy and PCR. Between April and July 2013, 800 households and 2,830 individuals were surveyed. Peripheral parasitaemia was detected in 37...
2016: PloS One
https://www.readbyqxmd.com/read/27785506/a-benchtop-capillary-flow-layer-by-layer-cf-lbl-platform-for-rapid-assembly-and-screening-of-biodegradable-nanolayered-films
#19
Ziye Dong, Ling Tang, Caroline C Ahrens, Zhenya Ding, Vi Cao, Steven Castleberry, Jiangtao Yan, Wei Li
Capillary flow layer-by-layer (CF-LbL) is a microfluidic platform for high throughput preparation and screening of nanolayered polymer films. Using a simple benchtop version of CF-LbL, we systematically studied the effects of various flow conditions and channel geometries on the thickness and surface roughness of the resulting films. We also investigated the biocompatibility and degradation behaviors of a series of enzymatically-degradable films made from naturally derived polymers, i.e. either alginate or hyaluronic acid as the anionic species and poly-l-arginine as the positive species...
October 27, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27775924/poly-l-lactic-acid-scaffold-with-oriented-micro-valley-surface-and-superior-properties-fabricated-by-solid-state-drawing-for-blood-contact-biomaterials
#20
Seung Hyuk Im, Youngmee Jung, Yangsoo Jang, Soo Hyun Kim
Most biomaterials composed of biodegradable polymers will contact either accidentally or consistently with blood and this commonly requires both good  mechanical strength and blood compatibility. Despite this demand, current processing methods still make it difficult and complex to simultaneously improve the two properties. To overcome present limitations, the aim of this work is to develop a solid-state drawing which is a novel method for blood-contact biomaterials that can simultaneously improve the two essential factors of mechanical strength and blood compatibility, as well as induce a micro-patterned surface...
October 24, 2016: Biofabrication
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