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Peripheral blood smear

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https://www.readbyqxmd.com/read/28077149/plasmodium-falciparum-malaria-co-infection-with-tick-borne-relapsing-fever-in-dakar
#1
Mamadou A Diallo, Baidy S Kane, Mouhamadou Ndiaye, Mouhamed Dieng, Khadim Diongue, Aida S Badiane, Mame Cheikh Seck, Daouda Ndiaye
BACKGROUND: West African tick-borne relapsing fever (TBRF) due to Borrelia crocidurae and malaria are co-endemics in Senegal. Although expected to be high, co-infections are rarely reported. A case of falciparum malaria and B. crocidurae co-infection in a patient from Velingara (South of Senegal) is discussed. CASE: A 28 year-old-male patient presented to Aristide Le Dantec Hospital for recurrent fever. He initially presented to a local post health of Pikine (sub-urban of Dakar) and was diagnosed for malaria on the basis of positive malaria rapid diagnostic test (RDT) specific to Plamodium falciparum...
January 11, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28070489/acute-disseminated-histoplasmosis-with-atypical-lymphocytosis-in-an-immunocompetent-host
#2
Ayman Elbadawi, Hamdy M A Ahmed, Hussain Adly, Mohamed A Elkhouly, Samar Abohamed, Ann R Falsey
65 year-old-male presented with a one-week history of high grade fever, fatigue and confusion which began abruptly two days after a cystoscopy procedure. Past medical history included pulmonary sarcoidosis diagnosed by mediastinal lymph biopsy, diabetes and hypertension. On admission he was febrile and confused with stable vital signs. Initial workup included negative Head CT and lumbar puncture. Blood work revealed normal metabolic and liver function tests with progressive anemia, thrombocytopenia and atypical lymphocytosis of 15-20%...
2017: IDCases
https://www.readbyqxmd.com/read/28060122/coinheritance-of-hereditary-elliptocytosis-and-deletional-hemoglobin-h-disease
#3
Pimlak Charoenkwan, Rungrote Natesirinilkul, Worawut Choeyprasert, Natchanon Kulsumritpon, Orapan Sangiamporn
Hereditary elliptocytosis is an inherited red blood cell membrane disorder characterized by typical peripheral blood smear findings of elliptocytes or rod-like red blood cells. Hemoglobin H disease is a form of α-thalassemia disease resulting in mild to moderate hemolytic anemia. The authors report 1 case of a girl who was diagnosed with oculo-auriculo-vertebral spectrum and a coinheritance of hereditary elliptocytosis and deletional hemoglobin H disease. She had moderate, non-transfusion-dependent anemia...
January 5, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28059092/bone-marrow-morphology-and-disease-progression-in-congenital-thrombocytopenia-a-detailed-clinicopathologic-and-genetic-study-of-eight-cases
#4
Hamilton C Tsang, James B Bussel, Susan Mathew, Yen-Chun Liu, Allison A Imahiyerobo, Attilio Orazi, Julia T Geyer
Patients with congenital thrombocytopenia have an increased risk of developing myeloid neoplasms. In these cases, the morphologic distinction between disease at baseline and at progression is challenging. This report analyzes clinicopathologic features of congenital thrombocytopenia with long-term follow-up at one referral center. Records from the last 20 years were searched for cases of congenital thrombocytopenia with bone marrow biopsies and peripheral blood smears. The clinical, morphologic, immunophenotypic, and molecular features were analyzed...
January 6, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28050450/iv-ferric-carboxymaltose-vs-oral-iron-in-the-treatment-of-post-partum-iron-deficiency-anaemia
#5
Sree Chandana Damineni, Suchitra Thunga
INTRODUCTION: Iron deficiency is the most common cause of Post-partum anaemia, reported as 50-60% in India. It is primarily due to inadequate iron intake and due to peripartum blood loss. It has been associated with significant post-partum complications. Therefore, Post-partum iron deficiency warrants greater attention and higher quality care. Oral iron treatment has been considered the standard of care. However, parenteral iron treatment is expected to be advantageous in cases where oral iron therapy is not possible...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050385/congenital-acute-myeloid-leukaemia-with-pseudo-chediak-higashi-like-granules-a-case-report
#6
Vandana Puri, Sandip Barman, Pooja Sharma, Meera Sikka
Congenital leukaemia is a very rare entity comprising 0.8% of all childhood leukaemias. Pseudo-Chediak-Higashi Anomaly (PCHA) in acute leukaemia is a rarely described entity. However, co-existence of congenital myeloid leukaemia with PCHA is a very rare entity and to the best of our knowledge has not been described in literature till date. A full term new-born presented on the 27(th) day of life with severe gastroenteritis. Complete blood counts and peripheral smear examination revealed leucocytosis with presence of 76% blast cells...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050381/spectrum-of-changes-in-rbc-indices-and-histograms-in-blood-from-subjects-with-cold-antibodies
#7
Chidambharam Choccalingam, Aarthi Kannan
Cold antibodies are mostly immunoglobulin M, which interact with red cell antigens at lower temperatures (<37°C). The analysis of samples from subjects with cold antibodies in automated haematology analysers may show abnormal Red Blood Corpuscles (RBC) indices and changes in histogram. High Mean Corpuscular Haemoglobin (MCH) and Mean Haemoglobin Concentration (MCHC) along with plateau effect beyond 110fl at Upper Discriminator (RU) end of RBC histogram are good indicators of presence of cold antibodies in plasma...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050380/coincidental-finding-of-beta-thalassaemia-minor-in-a-patient-of-lacquer-thinner-poisoning-presenting-as-methaemoglobinemia
#8
Charu Agarwal, Anisha Mohanpuria, Gurdeep Buxi, Vijay Kumar
Lacquer thinner, commonly used for removing household paints, is known to contain various aromatic hydrocarbons and naphtha; if ingested, may cause methaemoglobinemia. We report a case of 13-year-old girl who presented with episodes of vomiting, abdominal pain and numbness of limbs. Peripheral blood smear showed few fragmented erythrocytes and 10-12 nucleated red blood cells /100 white blood cells. Reticulocyte count was 15% with presence of Heinz bodies. There was a history of accidental ingestion of lacquer paint thinner...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28049536/usefulness-of-a-biomarker-to-identify-placental-dysfunction-in-the-context-of-malaria
#9
REVIEW
Alexandra Gueneuc, Philippe Deloron, Gwladys I Bertin
In most tropical areas, pregnant women are at increased risk of malaria, as a consequence of the massive sequestration of parasitized red blood cells in the placenta. The placenta plays a key role in embryonic and fetal development as well as in maternal-fetal exchanges, and pregnancy-associated malaria may alter selected placenta functions that lead to stillbirth and low birth weight. Although there are several tools (blood smear examination, RDT, PCR) to diagnose malaria infection during pregnancy, there is currently no test to assess placenta dysfunction in the framework of pregnancy-associated malaria...
January 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28042208/utility-of-peripheral-film-findings-and-its-correlation-with-automated-analyzer-an-audit-from-tertiary-care-hospital
#10
Sidra Asad, Imran Ahmed, Natasha Ali
BACKGROUND AND OBJECTIVE: With the advent of automated hematology analyzer, the use of traditional microscopy of blood film has become limited. The objective of our study was to determine the percentage of peripheral blood smear review in our institution in the era of automation and to identify reasons of manual review. MATERIALS AND METHODS: This was a prospective audit from January 1, 2015, to January 15, 2015. Consecutive complete blood count (CBC) samples and peripheral smear requests made up the sample size...
January 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28036138/early-diagnosis-of-ehrlichia-ewingii-infection-in-a-lung-transplant-recipient-by-peripheral-blood-smear
#11
Hariharan Regunath, Christian Rojas-Moreno, Juan P Olano, Richard D Hammer, William Salzer
Ehrlichiosis in lung transplant (LT) recipients is associated with severe outcomes. Ehrlichia ewingii is a less frequent cause of symptomatic ehrlichiosis, characterized by cytoplasmic inclusions (morulae) within circulating neutrophils. We report a case of E. ewingii infection in a LT recipient diagnosed promptly by blood smear exam and confirmed with molecular studies. This article is protected by copyright. All rights reserved.
December 30, 2016: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28032111/epidemiological-study-of-endemic-relapsing-fever-in-hamadan-province-west-of-iran
#12
Mansour Nazari, Ali Najafi
BACKGROUND: Endemic relapsing fever remains under diagnosed in our area according to a low index of suspicion among clinicians, as well as its difficult diagnosis. The goal of this study was to present the epidemiological aspects of the disease in western Iran. METHODS: In this analytical-descriptive cross-sectional study, the epidemiological and clinical aspects of relapsing fever were investigated in Hamadan Province, western Iran from 1999 to 2013. A confirmed patient was defined as a person who had both febrile illness and detected spirochetes by Wright-Giemsa or dark-field microscopy in a peripheral blood smear...
December 2016: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/28031855/neurologic-symptoms-as-the-only-manifestation-of-b12-deficiency-in-a-young-patient-with-normal-hematocrit-mcv-peripheral-blood-smear-and-homocysteine-levels
#13
Panagiota Voukelatou, Ioannis Vrettos, Andreas Kalliakmanis
B12 deficiency is associated with several neurological manifestations. It is well documented that neurologic symptoms due to B12 deficiency may sometimes present in the absence of anemia. However, in most cases there are several indicating factors like megaloblastic changes in complete blood count, hypersegmentated neutrophils or macroovalocytes in peripheral blood smear and abnormal homocysteine levels. In this report, we describe a case of a 32-year-old man with neurological symptomatology as the only manifestation of B12 deficiency with normal hematocrit, mean cell volume, peripheral blood smear and homocysteine levels...
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28018917/micronucleated-erythrocytes-in-peripheral-blood-from-neonate-rats-exposed-by-breastfeeding-to-cyclophosphamide-colchicine-or-cytosine-arabinoside
#14
Belinda C Gómez-Meda, Luis R Bañales-Martínez, Ana L Zamora-Perez, María de Lourdes Lemus-Varela, Xóchitl Trujillo, María G Sánchez-Parada, Blanca M Torres-Mendoza, Juan Armendáriz-Borunda, Guillermo M Zúñiga-González
Genotoxic exposure to chemical substances is common, and nursing mothers could transmit harmful substances or their metabolites to their offspring through breast milk. We explored the possibility of determining genotoxic effects in the erythrocytes of breastfeeding rat pups whose mothers received a genotoxic compound while nursing. Ten groups of female rats and five pups per dam were studied. The control group received sterile water, and the experimental groups received one of three different doses of cyclophosphamide, colchicine, or cytosine-arabinoside...
2016: BioMed Research International
https://www.readbyqxmd.com/read/28006767/a-2-year-longitudinal-prospective-study-of-the-effects-of-eltrombopag-on-bone-marrow-in-patients-with-chronic-immune-thrombocytopenia
#15
Russell K Brynes, Raymond S M Wong, Maung M Thein, Kalpana K Bakshi, Paul Burgess, Dickens Theodore, Attilio Orazi
BACKGROUND: The long-term effects of eltrombopag on bone marrow (BM) reticulin and/or collagen deposition in previously treated adults with chronic immune thrombocytopenia (ITP) were assessed. METHODS: Three BM biopsies were collected at baseline and after 1 and 2 years of eltrombopag treatment. Specimens were centrally processed, stained for reticulin and collagen, independently reviewed by 2 hematopathologists, and rated according to the European Consensus 0-3 scale of marrow fibrosis (MF)...
December 23, 2016: Acta Haematologica
https://www.readbyqxmd.com/read/28005510/case-237-renal-cell-carcinoma-with-osseous-metaplasia
#16
Billy Ming Hei Lai, Solomon Yig Joon Ka, Wai Kuen Kan, Man Wah Lam, Tang Fei Lee, Yun Hoi Lui, Jennifer Lai San Khoo
History A 47-year-old man presented with palpitations and decreased exercise tolerance. A peripheral blood smear revealed anemia, thrombocytopenia, and blast cells, and a diagnosis of acute myeloid leukemia was made. Immunohistochemistry revealed positivity for cluster of differentiation (or CD) markers, which have been reported to be associated with an increased risk of extramedullary leukemic involvement. Thus, contrast material-enhanced computed tomography (CT) of the thorax, abdomen, and pelvis was requested to enable exclusion of any extramedullary extension of leukemia...
January 2017: Radiology
https://www.readbyqxmd.com/read/27920980/phagocytized-candida-albicans-in-the-peripheral-blood-smear-of-a-girl-with-crohn-disease
#17
Kiyozumi Suzuki, Takahiro Kudo, Yuji Hirai
No abstract text is available yet for this article.
2017: IDCases
https://www.readbyqxmd.com/read/27891372/experience-with-splenic-abscess-from-southern-india
#18
Mallikarjuna Shetty, Swaroopa Deme, Knkj Mohan, Krishna Prasad Adiraju, Nageswar Rao Modugu, Naval Chandra, Amvr Narendra, Sathyanarayana Raju Yadati
INTRODUCTION: Splenic abscess is a rare entity with potentially life threatening complications. Sparse recent published data are available documenting the aetiological profile and management of patients with splenic abscess from India. AIM: To study the clinical profile of splenic abscess. MATERIALS AND METHODS: We retrospectively collected data from case records of admitted patients with splenic abscesses, to Nizam's Institute of Medical Sciences and Hospital which is a multispecialty, tertiary care referral hospital over a period of 15 months (from March 2014 to May 2015) and parameters studied were age, sex, symptoms, signs, risk factors, investigations like Ultrasound, CT scan, blood & microbiological culture, treatment and outcome...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27884837/characteristic-peripheral-blood-smear-findings-in-disorders-of-cobalamin-metabolism
#19
Hojun Li, Colin Sieff
No abstract text is available yet for this article.
November 24, 2016: Blood
https://www.readbyqxmd.com/read/27876944/seasonal-incidence-of-parasitic-diseases-in-bovines-of-south-western-gujarat-junagadh-india
#20
Binod Kumar, B R Maharana, Amit Prasad, Joice P Joseph, Bhavika Patel, J S Patel
The current study was conducted to investigate the incidence of parasitic diseases in bovines which were sick and brought at veterinary hospital for treatment. A total of 366 samples were investigated from cattle (n = 175) and buffaloes (n = 191) presented at Teaching Veterinary Clinical Complex (TVCC), Veterinary College, Junagadh, Gujarat during January to December 2014. Examination of Giemsa-stained peripheral blood smears exhibited that 58.6 % of cattle and 41.2 % of buffaloes were infected with haemoparasites comprising Babesia bigemina, Theileria annulata, and Anaplasma marginale @ of 54...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
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