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rectal neoplasm

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https://www.readbyqxmd.com/read/29707157/microbiota-effects-on-cancer-from-risks-to-therapies
#1
REVIEW
Domenica Rea, Giovanni Coppola, Giuseppe Palma, Antonio Barbieri, Antonio Luciano, Paola Del Prete, Sabrina Rossetti, Massimiliano Berretta, Gaetano Facchini, Sisto Perdonà, Maria Caterina Turco, Claudio Arra
Gut microbiota, a group of 1014 bacteria, eukaryotes and virus living in gastrointestinal tract, is crucial for many physiological processes in particular plays an important role in inflammatory and immune reactions. Several internal and external factors can influence this population, and shifts in their composition, have been demonstrated to contribute and affect different diseases. During dysbiosis several bacteria related to inflammation, one of the most necessary factors in carcinogenesis; it has been shown that some bacterial strains through deregulation of different signals/pathways may affect tumor development through the production of many factors...
April 3, 2018: Oncotarget
https://www.readbyqxmd.com/read/29682710/-surgical-skills-in-the-prevention-of-anastomotic-leakage-after-rectal-neoplasm-surgery
#2
Qianqian Shao, Guole Lin
For colorectal surgeons, how to reduce anastomotic leakage after laparoscopic rectal cancer surgery remains to be challenging. We provide a brief discussion regarding the surgical skills required to prevent anastomotic leakage after rectal cancer surgery, such as the following: 1) Low ligation of inferior mesenteric vessel during laparoscopic total mesorectal excision can improve anastomotic tension and blood supply, thus reducing the risk of anastomotic leakage. While high ligation of inferior mesenteric artery results in poor blood supply and high tension in atastomotic site, thus increasing the risk of anastomotic leakage...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29676706/-a-man-with-abdominal-pain-diarrhoea-and-rectal-bleeding
#3
A J M Oosterwijk, J W van den Berg, C C van Rossem
A 49-year-old man came to the emergency room with abdominal pain, vomiting, diarrhoea and rectal bleeding. Both colonoscopy and CT of the abdomen showed cecocolic intussusception caused by an appendiceal mucocele. An ileocecal resection was performed via a laparoscopic approach and microscopy of the tissue showed a low-grade mucinous neoplasm.
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29670522/dabigatran-added-to-dual-antiplatelet-therapy-to-treat-a-left-ventricular-thrombus-in-an-87-year-old-patient-with-myocardial-infarction-and-very-high-bleeding-risk
#4
Maria Noflatscher, Nicolas Moes, Eva-Maria Gassner, Peter Marschang
Background: A left ventricular (LV) thrombus is detected in approximately 5-10% of patients after myocardial infarction (MI). If left untreated, these LV thrombi carry a significant risk of complications including embolic stroke. According to current guidelines, anticoagulation with vitamin K antagonists (VKA) is recommended to treat a LV thrombus. Case presentation: An 87 year old patient was referred to our department with non ST-elevation MI. Five months before, he had been diagnosed with a subacute ST elevation MI, which had been treated conservatively...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29665665/-risk-factors-for-low-anterior-resection-syndrome
#5
G J Wu, W W Jia, Q An, T Yu, X L Cao, G Xiao
Objective: While low anterior resection avoided a permanent stoma, it might also cause bowel dysfunction which can significantly impact patients' quality of life. The objective of this study was to identify the incidence and risk factors for the development of bowel dysfunction following rectal surgery. Methods: Patients undergoing anterior resection for rectal neoplasm between January 2010 and December 2015 were identified from a rectal cancer database at the Department of Gastrointestinal Surgery, Beijing Hospital...
March 27, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29615301/early-onset-sporadic-colorectal-cancer-worrisome-trends-and-oncogenic-features
#6
REVIEW
Giulia Martina Cavestro, Alessandro Mannucci, Raffaella Alessia Zuppardo, Milena Di Leo, Elena Stoffel, Giovanni Tonon
Early onset colorectal cancers, defined as arising before 50 years of age, are a growing health hazard in western and eastern countries alike. The incidence of colon and rectal cancers in young individuals is projected to increase by as much as 90% and 140%, respectively, by 2030. Although several known cancer risk factors (e.g. smoking, alcohol, dietary habits) have been investigated, there is no single compelling explanation for this epidemiological trend. While some early onset colorectal cancers have been associated with germline mutations in cancer predisposition genes, genetic syndromes are implicated in only a fraction of these cancers (20%) and do not explain the rising incidence...
February 23, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29607825/transanal-minimally-invasive-surgery-tamis-first-in-kuwait-a-case-report
#7
Abdullah A AlHaddad, Ali S Mouzannar, Bader Marafi, Ibtisam Albader, Mona A Khoursheed, Ali Sayed Ahmed Alsayed
Transanal Minimally Invasive Surgery (TAMIS) is a one of new platform used to help and achieve better outcome in using transanal approach for the treatment of rectal neoplasm. High definition camera and high tech equipment are used to perform this kind of surgery. The main benefit of using this approach is to provide the best outcome or the patient compared to the traditional transanal approach. This platform can be used for a variety of cases, benign and malignant tumor and for the benign condition. We report the first TAMIS perfo b rmed in the Kuwait and probably in the Middle East with 2 years of follow up...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607400/a-circumferential-rectal-superficial-neoplasm-resected-with-endoscopic-submucosal-dissection-using-the-pocket-creation-method
#8
Rafiz Abdul Rani, Naohisa Yoshida, Takaaki Murakami, Kiyoshi Ogiso, Ryohei Hirose, Yutaka Inada, Hideyuki Konishi, Yuji Naito, Mitsuo Kishimoto, Takashi Ando, Yoshito Itoh
Endoscopic submucosal dissection (ESD) is recognized as an important technique in the nonsurgical management of early gastrointestinal carcinoma and it is continuously undergoing evolution in terms of technique and equipment. The pocket-creation method was recently developed for overcoming various difficulties such as large tumor size and severe fibrosis in ESD. Circumferential ESDs are rare and pose technical difficulties. We present a case of a circumferential rectal ESD using a pocket-creation method with two pockets...
April 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29552659/management-of-rectal-gastrointestinal-stromal-tumor
#9
REVIEW
Hitoshi Kameyama, Tatsuo Kanda, Yosuke Tajima, Yoshifumi Shimada, Hiroshi Ichikawa, Takaaki Hanyu, Takashi Ishikawa, Toshifumi Wakai
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal tract. However, rectal GIST is rare, the incident rate of it is approximately 5% of all GISTs. Rectal GIST symptoms generally include bleeding and/or pain and occasionally, urinary symptoms. Immunohistochemical evaluation finds that most rectal GIST tumors are CD117 (KIT) positive, and are sometimes CD34, platelet-derived growth factor receptor alpha (PDGFRA), smooth muscle actin, S-100, or vimentin positive...
2018: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29508218/comparative-quality-of-life-in-patients-following-transanal-minimally-invasive-surgery-and-healthy-control-subjects
#10
Stefan H E M Clermonts, Yu-Ting van Loon, Dareczka K Wasowicz, Barbara S Langenhoff, David D E Zimmerman
BACKGROUND: Transanal minimally invasive surgery (TAMIS) is considered the successor of transanal endoscopic microsurgery (TEMS). It makes use of more readily available laparoscopic instruments and single-port access platforms with similar perioperative, clinical and oncological outcomes. Little is known about quality of life (QoL) outcomes after the use of TAMIS. The aim of this study was to assess QoL after TAMIS in our patients and compare this with QoL in the healthy Dutch population...
March 5, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29483418/-surgical-resection-of-an-intraductal-papillary-mucinous-carcinoma-observed-on-imaging-four-years-after-the-initial-diagnosis
#11
Hiroaki Seki, Nobutaka Yasui, Akihiko Shimada, Hidetoshi Matsumoto
We herein report a 75-year-old woman who presented with an intraductal papillary mucinous carcinoma(IPMC)who was treated with surgical resection 4 years after the initial diagnosis was made. She previously underwent a high anterior resection of the rectum for rectal cancer at 71 years of age. Preoperative CT revealed a multilocular cystic mass measuring 6 cm in size in the body of the pancreas, which was considered benign. We followed up the intraductal papillary mucinous neoplasm(IPMN) by using annual CT imaging for 4 years...
February 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29477926/colorectal-intussusception-secondary-to-primary-rectal-melanoma-a-novel-case-report
#12
Colin McQuade, Peadar S Waters, Ciara O'Brien, Stephen Crowther, William Torreggiani, Dara O Kavanagh
INTRODUCTION: Intussusception in adults is a rare condition, accounting for just 5% of all cases. Approximately 50% of cases of large intestine intussusception occur due to a malignant neoplasm. We present here a novel case report of colo-rectal intussusception arising secondary to a primary rectal melanoma. PRESENTATION OF CASE: We present the case of an 85 year-old patient, who underwent a colonoscopy for investigation of weight loss and altered bowel habit. At colonoscopy, a pigmented polypoid mass was visualised in the upper third of the rectum...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29460883/-efficacy-of-video-assisted-procedures-in-advanced-age-patients-with-colorectal-cancer
#13
Z B Khalilov, A Yu Kalinichenko, R Kh Azimov, I S Panteleeva, M A Chinikov, F S Kurbanov
AIM: To assess advisability of video-assisted surgery in advanced age patients with colorectal cancer. MATERIAL AND METHODS: The study involved 44 patients with large intestine tumors. There were 30 patients with colon cancer aged 78.0±1.1 years and 14 patients with rectal neoplasms aged 75.0±1.8 years. All of them underwent elective video-assisted resections without conversion of the approach. RESULTS: Good and satisfactory results were achieved in 95...
2018: Khirurgiia
https://www.readbyqxmd.com/read/29456640/comparative-study-of-ultrasonic-elastography-and-conventional-ultrasound-in-diagnosis-of-malignant-anus-neoplasm
#14
Yicheng Zhu, Shuhao Deng, Yuan Zhang, Quan Jiang
The application value of conventional ultrasound and ultrasonic elastography (UE) in preoperative diagnosis and combined diagnosis of malignant anus neoplasms was investigated. One hundred and twenty patients, whose mass was detected by digital rectal examination, were examined using UE and conventional ultrasound before operation, and the results were compared with those of histopathological examinations after operation, so that the accuracy and imaging features of UE as well as UE combined with conventional ultrasound in diagnosing malignant anus neoplasm were analyzed...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29394856/-a-case-of-malignant-transformation-of-intraductal-papillary-mucinous-neoplasm-of-the-pancreas-accompanied-by-metachronous-triple-primary-cancer
#15
Takashi Noma, Hajime Hirose, Yoshito Ide, Hiroki Imamura, Yuriko Yagi, Yukako Mokutani, Yasuji Hashimoto, Kenichi Nagai, Jin Matsuyama, Masaru Kubota, Yukio Fukushima, Shigeyuki Tamura, Yo Sasaki
A 70's woman with a history of abdominal surgery for gastric cancer visited our hospital for the evaluation of bleeding during defecation.We diagnosed her with advanced rectal cancer and performed laparoscopic low anterior resection.As postoperative pathological staging was pT3N2M0, pStage III b, we included CapeOx therapy as adjuvant chemotherapy.One year and 4 months after the surgery, lung and liver metastases were revealed by CT and PET-CT scans.At the same time, dilatation of the main pancreatic duct(intraductal papillary mucinous neoplasm: IPMN)was detected...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29362908/diagnostic-utility-of-staging-abdominal-computerized-tomography-and-repeat-endoscopy-in-detecting-localization-errors-at-initial-endoscopy-in-colorectal-cancer
#16
Arash Azin, Trevor Wood, Dhruvin Hirpara, Emily Le Souder, Sami A Chadi, Timothy Jackson, Allan Okrainec, Fayez A Quereshy
BACKGROUND: Colonoscopy has a reported localization error rate as high as 21% in detecting colorectal neoplasms. Preoperative repeat endoscopy has been shown to be protective against localization errors. There is a paucity of literature assessing the utility of staging computerized tomography (CT) and repeat endoscopy as diagnostic tools for detecting localization errors following initial endoscopy. The objective of this study is to determine the diagnostic characteristics of staging CT and repeat endoscopy in correcting localization errors at initial endoscopy...
January 23, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29337771/outcomes-of-closed-versus-open-defects-after-local-excision-of-rectal-neoplasms-a-multi-institutional-matched-analysis
#17
Lawrence Lee, Ashley Althoff, Kimberley Edwards, Matthew R Albert, Sam B Atallah, Iain A Hunter, James Hill, John R T Monson
BACKGROUND: The management of the rectal wall defect after local excision of rectal neoplasms remains controversial, and the existing data are equivocal. OBJECTIVE: This study aimed to determine the effect of open versus closed defects on postoperative outcomes after local excision of rectal neoplasms. DESIGN: Data from 3 institutions were analyzed. Propensity score matching was performed in one-to-one fashion to create a balanced cohort comparing open and closed defects...
February 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29205758/transanal-endoscopic-microsurgery-a-new-zealand-experience
#18
Ian Bloomfield, Roelof Van Dalen, Simione Lolohea, Linus Wu
BACKGROUND: Transanal endoscopic microsurgery (TEMS) is a proven alternative therapy to either radical surgery or endoscopic mucosal resection for rectal neoplasms. It has proven benefits with lower morbidity and mortality compared with total mesorectal excision, and a lower local recurrence rate when compared to endoscopic mucosal techniques. METHODS: A retrospective data collection of TEMS procedures performed through Waikato District Health Board, New Zealand, from 2010 to 2015 was conducted...
December 3, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29181074/hindgut-neuroendocrine-neoplasms-characteristics-and-prognosis
#19
Paweł Gut, Joanna Waligórska-Stachura, Agata Czarnywojtek, Nadia Sawicka-Gutaj, Maciej Bączyk, Katarzyna Ziemnicka, Kosma Woliński, Ariadna Zybek, Jakub Fischbach, Marek Ruchała
Introduction: The aim of the study was to analyze the clinicopathologic characteristics and prognostic factors of hindgut-rectal neuroendocrine neoplasms. Material and methods: The study included 38 patients with rectal neuroendocrine tumors who were treated at the Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznan, Poland from February 2010 to December 2015. The clinicopathological data were retrospectively reviewed, extracted, analyzed, and patients were followed up to determine their survival status...
October 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29102525/clinical-impact-of-endoscopic-ultrasonography-on-the-management-of-neuroendocrine-tumors-lights-and-shadows
#20
REVIEW
Alessandra Zilli, Paolo Giorgio Arcidiacono, Dario Conte, Sara Massironi
The incidence of gastroenteropancreatic neuroendocrine neoplasms has increased in the recent decades. An extensive bibliographical search was performed in PubMed to identify guidelines and primary literature (retrospective and prospective studies, systematic reviews, case series) published mostly between year 1997 and June 2017, using both medical subject heading (MeSH) terms and free-language keywords about the accuracy and diagnostic and therapeutic role of endoscopic ultrasound in the context of gastro-entero-pancreatic neuroendocrine neoplasms...
January 2018: Digestive and Liver Disease
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