Giulia Nocentini, Graeme Maclaren, Robert Bartlett, Daniele De Luca, Salvatore Perdichizzi, Francesca Stoppa, Marco Marano, Corrado Cecchetti, Daniele G Biasucci, Angelo Polito, Abdullah Alghobaishi, Yit Guner, Sharada H Gowda, Ronald B Hirschl, Matteo Di Nardo
Perfluorocarbons (PFCs) are organic liquids derived from hydrocarbons in which some of the hydrogen atoms have been replaced by fluorine atoms. They are chemically and biologically inert substances with a good safety profile. They are stable at room temperature, easy to store, and immiscible in water. Perfluorocarbons have been studied in biomedical research since 1960 for their unique properties as oxygen carriers. In particular, PFCs have been used for liquid ventilation in unusual environments such as deep-sea diving and simulations of zero gravity, and more recently for drug delivery and diagnostic imaging...
August 4, 2023: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs