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https://www.readbyqxmd.com/read/28087721/joubert-syndrome-neuroimaging-findings-in-110-patients-in-correlation-with-cognitive-function-and-genetic-cause
#1
Andrea Poretti, Joseph Snow, Angela C Summers, Aylin Tekes, Thierry A G M Huisman, Nafi Aygun, Kathryn A Carson, Dan Doherty, Melissa A Parisi, Camilo Toro, Deniz Yildirimli, Meghana Vemulapalli, Jim C Mullikin, Andrew R Cullinane, Thierry Vilboux, William A Gahl, Meral Gunay-Aygun
BACKGROUND: Joubert syndrome is a clinically and genetically heterogeneous ciliopathy. Neuroimaging findings have not been systematically evaluated in a large cohort of patients with Joubert syndrome in correlation with molecular genetic cause and cognitive function. METHODS: Brain MRI of 110 patients with Joubert syndrome was included in this study. A comprehensive evaluation of brain MRI studies for infratentorial and supratentorial morphological abnormalities was performed...
January 13, 2017: Journal of Medical Genetics
https://www.readbyqxmd.com/read/28079874/cerebral-modulation-of-the-autonomic-nervous-system-in-term-infants
#2
N Schneebaum Sender, R B Govindan, M T Whitehead, A N Massaro, M Metzler, J Wang, Y I Cheng, A J du Plessis
OBJECTIVE: Central topography of autonomic nervous system (ANS) function has yet to be fully deciphered. In adults it has been shown to lateralize sympathetic and parasympathetic influence predominantly to the right and left cerebral hemispheres, respectively. We examined functional topography of central ANS in newborn subjects utilizing spectral analysis of heart rate variability (HRV), an established measure of ANS function. STUDY DESIGN: We studied newborns with hypoxic-ischemic encephalopathy participating in a prospective study undergoing a therapeutic hypothermia protocol...
January 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28075000/-bromocriptine-could-it-be-the-cure-for-post-surgical-akinetic-mutism
#3
A Arevalo-Saenz, M Pedrosa-Sanchez, R G Sola
INTRODUCTION: Akinetic mutism is considered as an alteration of the motivational state of the person, which the patient is unable to initiate verbal or motor responses voluntary, even with preserved sensorimotor and surveillance functions. CASE REPORT: A 43 year-old male involved in a cerebellum arteriovenous fistula complicated with hydrocephalus, who responded dramatically to treatment with bromocriptine. CONCLUSION: Typically, akinetic mutism is described as a transient surgeries posterior fossa...
January 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28074148/apraxia-of-speech-and-cerebellar-mutism-syndrome-a-case-report
#4
E De Witte, I Wilssens, D De Surgeloose, G Dua, M Moens, J Verhoeven, M Manto, P Mariën
BACKGROUND: Cerebellar mutism syndrome (CMS) or posterior fossa syndrome (PFS) consists of a constellation of neuropsychiatric, neuropsychological and neurogenic speech and language deficits. It is most commonly observed in children after posterior fossa tumor surgery. The most prominent feature of CMS is mutism, which generally starts after a few days after the operation, has a limited duration and is typically followed by motor speech deficits. However, the core speech disorder subserving CMS is still unclear...
2017: Cerebellum & Ataxias
https://www.readbyqxmd.com/read/28068964/management-of-screwdriver-induced-penetrating-brain-injury-a-case-report
#5
Jia Shi, Yumin Mao, Jiachao Cao, Bo Dong
BACKGROUND: Penetrating brain injury (PBI) can be caused by several objects ranging from knives to chopsticks. However, an assault with long and electric screwdriver is a peculiar accident and is relatively rare. Because of its rarity, the treatments of such injury are complex and nonstandardized. CASE PRESENTATION: We presented a case of a 54-year-old female who was stabbed with a screwdriver in her head and accompanied by loss of consciousness for 1 h. Computer tomography (CT) demonstrated that the screwdriver passed through the right zygomatic bone to posterior cranial fossa...
January 10, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28064327/application-of-neuroendoscopy-in-the-surgical-treatment-of-complicated-hemifacial-spasm
#6
Ming Zhi, Xiao J Lu, Qing Wang, Bing Li
OBJECTIVE: To explore the value of neuroendoscopy in surgery for primary hemifacial spasm (HFS) in patients with complicated local anatomy. METHODS: Endoscopic-assisted microvascular decompression (MVD) was performed in 42 patients with HFS with complicated local anatomy from Janurary 2008 to Janurary 2012 in our department, in the event of a significant blind spot, endoscopic exploration was performed with multi-angle 360-degree observation, including exploration of the brainstem facial nerve root exit zone (REZ) and exploration of the distal end of the nerve, and the relationships between blood vessels and nerves were carefully determined...
January 2017: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/28057591/surgical-management-of-spontaneous-spinal-cerebrospinal-fluid-epidural-fistula
#7
Declan G Siedler, Imogen M Ibbett, Nova B Thani
BACKGROUND: Intracranial hypotension secondary to spontaneous spinal cerebrospinal fluid (CSF) fistula is a rare condition which can have serious sequelae. Early diagnosis and treatment can be challenging. CASE DESCRIPTION: We present a case of a 17-year-old man who presented with a history of sudden onset, postural headaches, associated with upper thoracic back pain. Magnetic Resonance Imaging (MRI) demonstrated a thoracic extradural fluid collection and slumping of the brain within the posterior fossa...
January 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28050992/dautrey-s-procedure-revisited-in-management-of-recurrent-mandibular-dislocation
#8
Joanna Baptist, Mohan Baliga
Mandibular dislocation occurs when the condylar head glides out of the glenoid fossa with the condyle positioned in such a way that its posterior articulating surface lying ahead of the articular eminence. Recurrent mandibular dislocation is relatively uncommon. Patient is extremely distressed and goes through a lot of discomfort. Varied etiologies have been cited in the literature, such as keeping the mouth wide open for long periods of time during dental procedures, yawning, laughing, traumatic injuries to the mandible, psychiatric disturbances, and certain drugs...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28050719/sudden-benzodiazepine-induced-resolution-of-post-operative-pediatric-cerebellar-mutism-syndrome-a-clinical-spect-study
#9
Francesco Nicita, Milena Paiano, Mauro Liberatore, Alberto Spalice, Paola Papoff, Mariacristina Ullo, Manolo Piccirilli, Anna Clerico, Amalia Schiavetti
Post-operative pediatric cerebellar mutism syndrome (PPCMS) is a clinical syndrome arising from cerebellar injury and characterized by absence of speech and other possible symptoms and signs. Rare reports described some benefit after administration of dopamine agonist therapy, but no treatment has proven efficacy. In this paper, we report on the dramatic, sudden resolution of PPCMS induced by midazolam administration in a boy who underwent posterior fossa surgery for choroid plexus papilloma of the fourth ventricle...
January 3, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28049593/quantitative-and-computed-tomography-anatomic-analysis-of-glenoid-fixation-for-superior-capsule-reconstruction-a-cadaveric-study
#10
Jason M Schon, J Christoph Katthagen, Cameron N Dupre, Justin J Mitchell, Travis Lee Turnbull, Christopher R Adams, Patrick J Denard, Peter J Millett
PURPOSE: To investigate glenoid fixation for superior capsule reconstruction (SCR) and evaluate anchor positions, intraosseous trajectories, and proximity to the suprascapular nerve (SSN) and glenoid fossa. The secondary purpose was to provide technical pearls and pitfalls for anchor insertion on the superior glenoid during SCR. METHODS: Three beath pins were arthroscopically inserted into 12 (n = 12) nonpaired human cadaveric shoulders through Neviaser, anterior, and posterior portals to simulate anchor placement on the superior glenoid during SCR...
December 31, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28049034/hypervascular-lesions-of-the-cerebellopontine-angle-the-relevance-of-angiography-as-a-diagnostic-and-therapeutic-tool-and-the-role-of-stereotactic-radiosurgery-in-management-a-comprehensive-review
#11
REVIEW
Yosef Laviv, Ajith Thomas, Ekkehard M Kasper
The cerebellopontine angle (CPA) is a narrowed skull base area, containing important cranial nerves and vessels and bordering with eloquent areas of the posterior fossa. Tumors of the CPA are a heterogeneous group and can arise extradural, intradural-extraaxial or intraaxial. Accordingly, their vascular supply changes, depending on their anatomical origin. Symptomatic, large CPA tumors require surgical resection in order to prevent irreversible, severe neurological damages. However, its tight and strategical location make surgery in the CPA very challenging and require appropriate pre-surgical planning...
December 31, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28048662/su-f-t-206-proton-treatment-techniques-for-posterior-fossa-tumors-consequences-for-let-and-dose-volume-parameters-for-the-brainstem-and-organs-at-risk
#12
D Giantsoudi, J Adams, S MacDonald, H Paganetti
PURPOSE: In proton radiation therapy of posterior fossa tumors, to spare other sensitive structures, the preferred beam geometry results in placing the treatment field distal edge within or just beyond the brainstem, including in at least partially in the treatment volume. Concerns for brainstem toxicity are increased and a controversy exists as to weather the beam's distal edge should be placed within the brainstem or beyond it, to avoid elevated linear energy transfer (LET) and relative biological effectiveness (RBE) within the brainstem...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046661/su-f-t-208-an-efficient-planning-approach-to-posterior-fossa-tumor-bed-boosts-using-proton-pencil-beam-scanning-in-fixed-beam-room
#13
N Ju, C Chen, S Gans, E Hug, O Cahlon, S Wolden, B Chon, B Yeh, H Tsai, K Sine, D Mah
PURPOSE: A fixed-beam room could be underutilized in a multi-room proton center. We investigated the use of proton pencil beam scanning (PBS) on a fixed-beam as an alternative for posterior fossa tumor bed (PF-TB) boost treatments which were usually treating on a gantry with uniform scanning. METHODS: Five patients were treated with craniospinal irradiation (CSI, 23.4 or 36.0 Gy(RBE)) followed by a PF-TB boost to 54 Gy(RBE) with proton beams. Three PF-TB boost plans were generated for each patient: (1) a uniform scanning (US) gantry plan with 4-7 posterior fields shaped with apertures and compensators (2) a PBS plan using bi-lateral and vertex fields with a 3-mm planning organ-at-risk volume (PRV) expansion around the brainstem and (3) PBS fields using same beam arrangement but replacing the PRV with robust optimization considering a 3-mm setup uncertainty...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025433/three-dimensional-changes-in-the-temporomandibular-joint-after-maxillary-protraction-in-children-with-skeletal-class-iii-malocclusion
#14
Hyunju Lee, Woo-Sung Son, Chun Kwak, Eun-Hee Kang, Seong-Sik Kim, Soo-Byung Park, Yong-Il Kim
We evaluated 3-dimensional changes in the temporomandibular joints of children with skeletal Class III malocclusion and maxillary deficiency after facemask therapy for maxillary protraction. Eighteen children with anterior crossbite and a Class III molar relationship underwent facemask therapy for maxillary protraction, after which they exhibited positive overjet and a Class II molar relationship. Three-dimensional cone-beam computed tomography images of the patients were obtained before (T1) and after (T2) facemask protraction, and the 3-dimensional coordinates of the anatomical landmarks in T1 and T2 images were compared...
2016: Journal of Oral Science
https://www.readbyqxmd.com/read/28017755/occipital-artery-pseudoaneurysm-following-posterior-fossa-craniotomy-case-report
#15
Visish M Srinivasan, Patrick J Karas, Anish N Sen, Jared S Fridley, Stephen Chen, Shankar P Gopinath
BACKGROUND: Pseudoaneurysms of scalp arteries have been reported in rare cases after iatrogenic injury, though they are far more commonly seen after traumatic injuries. They are usually associated with the superficial temporal artery (STA); however, there have been a few reports of psuedoaneurysms of the occipital artery (OA) CASE DESCRIPTION: We present a unique case of an OA pseudoaneurysm presenting with delayed postoperative hemorrhage following a retrosigmoid craniotomy. The psuedoaneurysm was treated by coil embolization...
December 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28013334/cerebellopontine-angle-medulloblastoma-with-extensive-nodularity-in-a-child-case-report-and-review-of-the-literature
#16
Raywat Noiphithak, Vich Yindeedej, Chatchai Thamwongskul
BACKGROUND: Cerebellar medulloblastomas (MBs) are one of the most common posterior fossa tumors in children but rarely occur in the cerebellopontine angle (CPA). Only 39 cases of CPA MBs were reported in the literature, and most of them were classic and desmoplastic MBs. CASE PRESENTATION: A 22-month-old girl presented with progressive cerebellar ataxia. Magnetic resonance imaging showed a large tumor in the right CPA and obstructive hydrocephalus. Surgical resection was performed and achieved total tumor removal...
December 24, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28009626/a-successful-course-of-electroconvulsive-therapy-in-a-patient-with-epilepsy-and-a-posterior-fossa-titanium-plate
#17
Rachel B Katz, Mesut Toprak, Robert Ostroff
No abstract text is available yet for this article.
December 21, 2016: Journal of ECT
https://www.readbyqxmd.com/read/27999713/intracranial-aneurysm-formation-after-radiotherapy-for-medulloblastoma
#18
Tomoya Kamide, Masanao Mohri, Kouichi Misaki, Naoyuki Uchiyama, Mitsutoshi Nakada
BACKGROUND: The development of an intracranial aneurysm after radiotherapy is rare but secondary effect of cranial irradiation in a primary disease treatment. CASE DESCRIPTION: The patient was a 17-year-old male adolescent who was diagnosed as having a posterior fossa medulloblastoma when he was 8 years old. He had undergone tumor resection with radiotherapy and chemotherapy. A distal posterior inferior cerebellar artery aneurysm was identified by magnetic resonance imaging 8 years after radiotherapy and grew rapidly throughout the next 1 year...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27999708/-hemangioblastomas-of-the-posterior-fossa-report-of-16-cases-and-literature-review
#19
Alvaro Campero, Pablo Ajler, Julio Fernandez, Gustavo Isolan, Martin Paiz, Conrado Rivadeneira
OBJECTIVE: The aim of this study is to describe the results of 16 patients with posterior fossa hemangioblastoma, treated with microsurgical techniques. METHOD: Between June 2005 and December 2015, 16 patients with posterior fossa hemangioblastoma were operated on, underwent microsurgical resection. The sex, age, imaging findings, symptoms, and postoperative results were analyzed. RESULTS: Eleven patients were men and 5 were women. The average age of the patients was 44 years...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27986346/proton-treatment-techniques-for-posterior-fossa-tumors-consequences-for-linear-energy-transfer-and-dose-volume-parameters-for-the-brainstem-and-organs-at-risk
#20
Drosoula Giantsoudi, Judith Adams, Shannon M MacDonald, Harald Paganetti
PURPOSE: In proton therapy of posterior fossa tumors, at least partial inclusion of the brainstem in the target is necessary because of its proximity to the tumor and required margins. Additionally, the preferred beam geometry results in directing the field distal edge toward this critical structure, raising concerns for brainstem toxicity. Some treatment techniques place the beam's distal edge within the brainstem (dose-sparing techniques), and others avoid elevated linear energy transfer (LET) of the proton field by placing the distal edge beyond it (LET-sparing techniques)...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
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