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https://www.readbyqxmd.com/read/28440972/a-comparison-between-the-diagnostic-accuracy-of-frozen-section-and-permanent-section-analyses-in-central-nervous-system
#1
Razie Amraei, Afshin Moradi, Hanieh Zham, Mahsa Ahadi, Maryam Baikpour, Azadeh Rakhshan
Objective: Using diagnostic pathological methods during surgery is a valuable means of determining the appropriate management for patients. Application of Frozen Section in CNS surgeries might face challenges due to friability of brain tissue and its relative inaccessibility. Various studies have evaluated the diagnostic acuity of frozen section compared to gold standard but results have been quite inconsistent. We conducted the present study to evaluate the accuracy of cryostat in diagnosing central nervous system tumors compared to the Gold Standard method...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28439163/superolateral-dislocation-of-bilateral-intact-mandibular-condyles-a-rare-case-series
#2
Satishkumar G Patil, Bindu S Patil, Udupikrishna Joshi, B M Rudagi, Aafreen Aftab
BACKGROUND AND PURPOSE: The dislocation of mandibular condyle is a clinical condition in which the head of condyle has been displaced out of the glenoid fossa. Complete dislocation of the mandibular condyle can occur in anterior, posterior, lateral and superior direction. Among these dislocations, bilateral superolateral dislocation of mandibular condyles is quite rare and often misdiagnosed. Because of its rare occurrence and unusual clinical course, the best treatment is debatable. PATIENTS AND METHOD: We present the first case series of true bilateral superolateral dislocation of intact mandibular condyles (Type 2B) without fracturing the Zygomatic arch, associated with symphysis fracture...
June 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28435113/microsurgical-and-endoscopic-anatomy-for-intradural-temporal-bone-drilling-and-applications-of-the-electromagnetic-navigation-system-various-extensions-of-the-retrosigmoid-approach
#3
Ken Matsushima, Noritaka Komune, Satoshi Matsuo, Michihiro Kohno
OBJECTIVE: The use of the retrosigmoid approach has recently been expanded by several modifications including the suprameatal, transmeatal, suprajugular, and inframeatal extensions. Intradural temporal bone drilling without damaging vital structures inside or beside the bone, such as the internal carotid artery and jugular bulb, is a key step for these extensions. This study aimed to examine the microsurgical and endoscopic anatomy of the extensions of the retrosigmoid approach, and to evaluate the clinical feasibility of an electromagnetic navigation system during intradural temporal bone drilling...
April 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28432426/posterior-cranial-fossa-tumours-in-children-at-national-cancer-institute-sudan-a-single-institution-experience
#4
Moawia Mohammed Ali Elhassan, Haytham Hussein Mohammed Osman, Jeannette Parkes
BACKGROUND: Posterior cranial fossa tumours (PCF) comprise 54-70% of childhood brain tumours. The clinical profile and outcomes of these tumours differ in area of the world. The aim of this study is to describe clinical characteristics, treatment and outcome of posterior cranial fossa tumours in Sudan. MATERIAL AND METHODS: A retrospective study of children diagnosed with posterior cranial fossa tumours and treated between January 1998 and December 2015 at National Cancer Institute, Sudan...
April 21, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28430083/hydrocephalus-treatment-in-children-long-term-outcome-in-975-consecutive-patients
#5
Pierre-Aurelien Beuriat, Stephanie Puget, Giuseppe Cinalli, Thomas Blauwblomme, Kevin Beccaria, Michel Zerah, Christian Sainte-Rose
OBJECTIVE Hydrocephalus remains one of the more common pathologies managed in pediatric neurosurgical units. Endoscopic third ventriculostomy (ETV) has an advantage over ventriculoperitoneal shunting as it enables patients to remain device free. Multiple shunt devices with various valve designs exist, with no one valve proven to be superior to another. The aim of this study was to describe the management of hydrocephalus and its long-term outcome. METHODS The authors retrospectively reviewed the medical records of all patients who had been treated for hydrocephalus at the Hôpital Necker-Enfants Malades in the period from 1985 to 1995...
April 21, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28427119/-genetic-analysis-of-posterior-cranial-fossa-morphology-in-families-of-chiari-malformation-type-%C3%A2
#6
X X Yuan, Y Li, S F Sha, W X Sun, Y Qiu, Z Liu, W G Zhu, Z Z Zhu
Objective: To explore genetic characteristic of posterior cranial fossa morphology in families of Chiari malformation type Ⅰ (CMI). Methods: From April 2010 to May 2016, a total of 47 cases of CMI families (CMI group) and their 94 parents (CMI-P group)collected were retrospectively reviewed in Department of Spinal Surgery, Drum Tower Hospital, School of Medicine, Nanjing University.Another cohort of 50 asymptomatic adults was enrolled to serve as the control group.Patients with skull fracture or other diseases which can lead to secondary CMI were excluded...
April 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28424875/erratum-to-neuropsychological-improvement-after-posterior-fossa-arachnoid-cyst-drainage
#7
M L Cuny, M Pallone, H Piana, N Boddaert, C Sainte-Rose, L Vaivre-Douret, P Piolino, S Puget
No abstract text is available yet for this article.
April 19, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28423966/linear-energy-transfer-distributions-in-the-brainstem-depending-on-tumour-location-in-intensity-modulated-proton-therapy-of-paediatric-cancer
#8
Lars Fredrik Fjæra, Zuofeng Li, Kristian S Ytre-Hauge, Ludvig P Muren, Daniel J Indelicato, Yasmin Lassen-Ramshad, Grete May Engeseth, Marianne Brydøy, Andrea Mairani, Stella Flampouri, Olav Dahl, Camilla H Stokkevåg
BACKGROUND: For tumours near organs at risk, there is concern about unintended increase in biological dose from elevated linear energy transfer (LET) at the distal end of treatment fields. The objective of this study was therefore to investigate how different paediatric posterior fossa tumour locations impact LET and biological dose to the brainstem during intensity-modulated proton therapy (IMPT). MATERIAL AND METHODS: Multiple IMPT plans were generated for four different simulated tumour locations relative to the brainstem for a five-year-old male patient...
April 19, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28422806/improvement-of-image-quality-in-unenhanced-dual-layer-ct-of-the-head-using-virtual-monoenergetic-images-compared-with-polyenergetic-single-energy-ct
#9
Victor Neuhaus, Nuran Abdullayev, Nils Große Hokamp, Gregor Pahn, Christoph Kabbasch, Anastasios Mpotsaris, David Maintz, Jan Borggrefe
OBJECTIVES: The aims of this study were to compare virtual monoenergetic images and polyenergetic images reconstructed from unenhanced dual-layer detector computed tomography (DLCT) of the head and to determine kiloelectron volt levels that optimize image quality, particularly the gray-white matter contrast, and reduce beam hardening artifacts caused by the skull. MATERIALS AND METHODS: Institutional review board approval was obtained. Forty patients that received DLCT were included in this retrospective study; of these patients, 22 were women and 18 were men...
April 19, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28409726/the-suboccipital-ligament
#10
Kelsey Alabaster, M Fred Bugg, Bruno Splavski, Frederick A Boop, Kenan I Arnautovic
OBJECTIVE A fibrous structure located dorsal to the dura at the posterior craniocervical junction stretches horizontally between the bilateral occipital condyles and the upper borders of the C-1 laminae. Partially covered by the occipital bone, this structure is always encountered when the bone is removed from the foramen magnum rim during approaches to the posterior cranial fossa. Although known to surgeons, this structure has not been defined, studied, or named. The most appropriate name for this structure is "the suboccipital ligament," and a detailed rationale for this name is provided...
April 14, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28409229/sphenoid-dysplasia-in-neurofibromatosis-type-1-a-new-technique-for-repair
#11
Di Rocco Concezio, Samii Amir, Tamburrini Gianpiero, Massimi Luca, Giordano Mario
PURPOSE: Sphenoid bone dysplasia in neurofibromatosis type 1 is characterized by progressive exophthalmos and facial disfiguration secondary to herniation of meningeal and cerebral structures. We describe a technique for reconstruction of the sphenoid defect apt at preventing or correcting the ocular globe dislocation. METHODS: After placement of spinal cerebrospinal fluid drainage to reduce intracranial pressure, the temporal pole is posteriorly dislocated extradurally...
April 13, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28408631/asymmetric-meckel-cave-enlargement-a-potential-marker-of-phaces-syndrome
#12
J N Wright, V Wycoco
BACKGROUND AND PURPOSE: PHACES syndrome is a complex of morphologic abnormalities of unknown cause and includes posterior fossa abnormalities; head and neck infantile hemangiomas; arterial, cardiac, and eye anomalies; and sternal or abdominal wall defects. Accurate identification of the syndrome is important for optimal treatment. The purpose of this study was to investigate the incidence of asymmetric Meckel cave enlargement, a potential novel imaging marker, in a population of patients referred for evaluation of possible PHACES syndrome...
April 13, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28405869/long-term-neuropsychological-follow-up-of-young-children-with-medulloblastoma-treated-with-sequential-high-dose-chemotherapy-and-irradiation-sparing-approach
#13
Taryn B Fay-McClymont, Danielle M Ploetz, Don Mabbott, Karin Walsh, Amy Smith, Susan N Chi, Elizabeth Wells, Jennifer Madden, Ashley Margol, Jonathan Finlay, Mark W Kieran, Douglas Strother, Girish Dhall, Roger J Packer, Nicholas K Foreman, E Bouffet, Lucie Lafay-Cousin
High-dose chemotherapy (HDC) strategies were developed in brain tumor protocols for young children to prevent neuropsychological (NP) impairments associated with radiotherapy. However, comprehensive NP evaluations of these children treated with such strategies remain limited. We examined the long-term neurocognitive outcomes of young children (<6 years) with medulloblastoma, treated similarly, with a HDC strategy "according to" the chemotherapy regimen of the protocol CCG 99703. This retrospective study included young children less than 6 years of age at diagnosis of medulloblastoma treated from 1998 to 2011 at 7 North American institutions...
April 12, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28399105/-treatment-of-syringomyelia-associated-with-chiari-1-malformation
#14
A A Zuev, G V Kostenko
Syringomyelia (SM) develops due to the disturbance of cerebrospinal fluid dynamics, spinal fixation or a spinal tumor. The disturbance of cerebrospinal fluid dynamics in the area of the foramen magnum leads to the progression of SM in Chiari 1 malformation (CM1). CM1 is the most prevalent pathology of craniovertebral junction associated with SM. The prevalence of CM1 varies from 3 to 8 per 100 000 population but SM is diagnosed in 65% of patients with CM1. Clinical symptoms of CM1 and SM include pain in the occipital area, gait disturbances due to sensitive ataxia, dissociated sensory disorders, dysphagia, paresis of the extremities...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28397323/anatomical-subgroup-analysis-of-the-meridian-cohort-posterior-fossa-abnormalities
#15
Paul D Griffiths, Karen Brackley, Michael Bradburn, Daniel Ja Connolly, Mary L Gawne-Cain, Mark D Kilby, Laura Mandefield, Cara Mooney, Stephen C Robson, Brigitte Vollmer, Gerald Mason
OBJECTIVE: To assess the diagnostic and clinical contribution of in utero magnetic resonance (iuMR) imaging in fetuses diagnosed with abnormalities of the posterior fossa as the only intracranial abnormality recognised on antenatal ultrasonography (USS). METHODS: We report a sub-group analysis of fetuses with abnormalities of the posterior fossa diagnosed on antenatal USS (with or without ventriculomegaly) from the MERIDIAN cohort who had iuMR imaging within 2 weeks of USS and outcome reference data were available...
April 11, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28397227/-prenatal-diagnosis-and-follow-up-of-a-case-with-lowe-syndrome-caused-by-interstitial-deletion-of-xq25-26
#16
Xiangyu Zhu, Jie Li, Tong Ru, Ruifang Zhu, Chenyan Dai, Wanjun Wang, Yali Hu
OBJECTIVE: To report on a sporadic case of Lowe syndrome diagnosed prenatally with ultrasound examination and genetic testing. METHODS: Detailed sonographic fetal screening was performed by an experienced sonographer at 32 weeks of gestation. Fetal cranial magnetic resonance imaging (MRI) was applied to detect potential brain abnormality. Chromosomal microarray analysis (CMA) was conducted on amniotic fluid sample from the fetus and peripheral blood sample from the mother...
April 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28387624/dolichoectatic-aneurysms-of-the-vertebrobasilar-system-clinical-and-radiographic-factors-that-predict-poor-outcomes
#17
David S Xu, Michael R Levitt, M Yashar S Kalani, Leonardo Rangel-Castilla, Celene B Mulholland, Isaac J Abecassis, Ryan P Morton, John D Nerva, Adnan H Siddiqui, Elad I Levy, Robert F Spetzler, Felipe C Albuquerque, Cameron G McDougall
OBJECTIVE Fusiform dolichoectatic vertebrobasilar aneurysms are rare, challenging lesions. The natural history of these lesions and medium- and long-term patient outcomes are poorly understood. The authors sought to evaluate patient prognosis after diagnosis of fusiform dolichoectatic vertebrobasilar aneurysms and to identify clinical and radiographic predictors of neurological deterioration. METHODS The authors reviewed multiple, prospectively maintained, single-provider databases at 3 large-volume cerebrovascular centers to obtain data on patients with unruptured, fusiform, basilar artery dolichoectatic aneurysms diagnosed between January 1, 2000, and January 1, 2015...
April 7, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28384976/computed-tomographic-evaluation-of-condylar-symmetry-and-condyle-fossa-relationship-of-the-temporomandibular-joint-in-subjects-with-normal-occlusion-and-malocclusion-a-comparative-study
#18
Vivek Reddy Ganugapanta, Swaroopa Rani Ponnada, Kranthi Praveen Raju Gaddam, Kiran Perumalla, Imran Khan, Naqeed Abdul Mohammed
INTRODUCTION: The relationship of the condyle and the mandibular fossa differs in shape with type of malocclusion and skeletal pattern. A review of literature shows till date there are no studies on Temporomandibular Joint (TMJ) condyle-fossa relation to the type of malocclusion based on growth pattern. Computed Tomography (CT) provides optimal imaging of the osseous components of the TMJ. AIM: The purpose of this study was to investigate the condyle-fossa relationship and the dimensional and positional symmetries between the right and left condyles in subjects with normal occlusion and malocclusion in different growth patterns utilizing the CT scans of the TMJ...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28384597/no-significant-difference-between-chiari-malformation-type-1-5-and-type-i
#19
Wei Liu, Hongxing Wu, Yalikun Aikebaier, Maoliti Wulabieke, Rexiti Paerhati, Xiaopeng Yang
OBJECTIVE: Chiari malformation Type 1.5 (CM 1.5) was defined as the association of Chiari malformation Type I (CM I) and brainstem herniation. The objective was to demonstrate the difference of clinical features and surgical outcomes between CM 1.5 and CM I. PATIENTS AND METHODS: All CM 1.5 and CM I adult patients who underwent posterior fossa decompression with duraplasty at our institution between 2006 and 2010 were retrospectively reviewed. Clinical characteristics, imaging features, and long-term outcomes were compared between CM 1...
March 30, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28382975/radiation-induces-progenitor-cell-death-microglia-activation-and-blood-brain-barrier-damage-in-the-juvenile-rat-cerebellum
#20
Kai Zhou, Martina Boström, C Joakim Ek, Tao Li, Cuicui Xie, Yiran Xu, Yanyan Sun, Klas Blomgren, Changlian Zhu
Posterior fossa tumors are the most common childhood intracranial tumors, and radiotherapy is one of the most effective treatments. However, irradiation induces long-term adverse effects that can have significant negative impacts on the patient's quality of life. The purpose of this study was to characterize irradiation-induced cellular and molecular changes in the cerebellum. We found that irradiation-induced cell death occurred mainly in the external germinal layer (EGL) of the juvenile rat cerebellum. The number of proliferating cells in the EGL decreased, and 82...
April 6, 2017: Scientific Reports
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