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https://www.readbyqxmd.com/read/29241706/placement-of-an-absorbable-rectal-hydrogel-spacer-in-patients-undergoing-low-dose-rate-brachytherapy-with-palladium-103
#1
Amandeep S Taggar, Tomer Charas, Gil'ad N Cohen, Keeratikarn Boonyawan, Marisa Kollmeier, Sean McBride, Nitin Mathur, Antonio L Damato, Michael J Zelefsky
PURPOSE: Rates of rectal toxicity after low-dose-rate (LDR) brachytherapy for prostate cancer are dependent on rectal dose, which is associated with rectal distance from prostate and implanted seeds. Placement of a hydrogel spacer between the prostate and rectum has proven to reduce the volume of the rectum exposed to higher radiation dose levels in the setting of external beam radiotherapy. We present our findings with placing a rectal hydrogel spacer in patients following LDR brachytherapy, and we further assess the impact of this placement on dosimetry and acute rectal toxicity...
December 11, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29237717/particulate-matter-air-pollution-exposure-and-heart-disease-mortality-risks-by-race-and-ethnicity-in-the-united-states-1997-2009-nhis-with-mortality-followup-through-2011
#2
Jennifer D Parker, Nataliya Kravets, Ambarish Vaidyanathan
Background -Most U.S. studies of mortality and air pollution have been conducted on largely non-Hispanic white study populations. However, many health and mortality outcomes differ by race and ethnicity, and non-Hispanic white persons experience lower air pollution exposures than those who are non-Hispanic black or Hispanic. This study examines whether associations between air pollution and heart disease mortality differ by race/ethnicity. Methods -We used data from the 1997-2009 National Health Interview Survey linked to mortality records through December 2011 and annual estimates of fine particulate matter (PM2...
December 13, 2017: Circulation
https://www.readbyqxmd.com/read/29234884/management-of-persistent-coccydynia-with-transrectal-manipulation-results-of-a-combined-procedure
#3
Ali Seker, Ilker Abdullah Sarikaya, Ozgur Korkmaz, Sercan Yalcin, Melih Malkoc, Ahmet Murat Bulbul
OBJECTIVE: We compared the results of manual therapy combined with steroid injection with single steroid injection in the treatment of persistent coccydynia. PATIENTS AND METHODS: Combined therapy was performed in 21 patients (Group 1) and steroid injection in 23 patients (Group 2). We compared two groups and investigated the combined therapy group in details. Patients were classified according to the underlying cause, BMI, anatomic type of coccyx and duration of symptoms (< 6 or ≥ 6 months)...
December 12, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29215503/minimum-detectable-measurement-difference-mdmd-for-health-related-quality-of-life-hrql-measures-varies-according-age-and-disability-in-adult-spinal-deformity-asd-implications-for-calculating-minimal-clinically-important-difference-mcid
#4
Michael P Kelly, Han Jo Kim, Christopher P Ames, Douglas C Burton, Leah Yacat Carreon, David W Polly, Richard Hostin, Amit Jain, Jeffrey L Gum, Virginie Lafage, Frank J Schwab, Christopher I Shaffrey, Justin S Smith, Shay Bess
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To investigate the minimum detectable measurement difference (MDMD) in the Scoliosis Research Society-22r (SRS-22r) outcomes instrument in adult spinal deformity (ASD) and to evaluate the effect of baseline data on measurable difference. SUMMARY OF BACKGROUND DATA: The minimum clinically important difference (MCID) is the smallest, clinically relevant change observed and has been proposed for the SRS-22r instrument in ASD as 0...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29202981/matrix-associated-stem-cell-transplantation-mast-in-chondral-defects-of-the-ankle-is-safe-and-effective-2-year-followup-in-130-patients
#5
Martinus Richter, Stefan Zech, Stefan Andreas Meissner
BACKGROUND: The aim of the study was to assess the 2-year-follow-up of matrix-associated stem cell transplantation (MAST) in chondral defects of the ankle. METHODS: In a prospective consecutive non-controlled clinical follow-up study, all patients with chondral defect that were treated with MAST from October 1, 2011 to July 31, 2013 were analyzed. Size and location of the chondral defects, method-associated problems and the Visual Analogue Scale Foot and Ankle (VAS FA) before treatment and at follow-up were analyzed...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29202773/process-evaluation-of-the-systematic-medical-appraisal-referral-and-treatment-smart-mental-health-project-in-rural-india
#6
Abha Tewari, Sudha Kallakuri, Siddhardha Devarapalli, Vivekanand Jha, Anushka Patel, Pallab K Maulik
BACKGROUND: Availability of basic mental health services is limited in rural areas of India. Health system and individual level factors such as lack of mental health professionals and infrastructure, poor awareness about mental health, stigma related to help seeking, are responsible for poor awareness and use of mental health services. We implemented a mental health services delivery model that leveraged technology and task sharing to facilitate identification and treatment of common mental disorders (CMDs) such as stress, depression, anxiety and suicide risk in rural areas of the state of Andhra Pradesh, India...
December 4, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29200491/metallosis-a-complication-in-the-guided-growing-rod-system-used-in-treatment-of-scoliosis
#7
Jae Hyuk Yang, Chang Hwa Ham, Yeok Gu Hwang, Seung Woo Suh
Soft tissue reaction following metallic debris formation with the use of guided growing rod system has not been previously reported in human. The purpose of this study is to report complications caused by metallosis in a guided growing rod system. A 9-year-old female patient, who underwent treatment for the progressive idiopathic scoliosis (with Cobb's angle of 71°) with the guided growing rod system. Her Cobb's angle was corrected to 13° with the index surgery. During the 5 years postoperative period, she manifested recurrent episodes of skin irritation and progressive worsening of lateral curvature of the spine to an angle of 57°...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200490/management-of-nail-bed-injuries-associated-with-fingertip-injuries
#8
Alexander George, Reena Alexander, C Manju
Background: Management of nail injuries can often be a challenging experience, especially in presence of complex fingertips' injuries that include soft tissue loss and distal phalanx injury. Most studies found in the literature focus on individual injuries and describe methods to tackle those injuries, notwithstanding the fact that the nail, nailbed, distal phalanx, soft tissue and skin of the finger tip form a complex and often more than one element of this complex is injured. This retrospective study therefore focuses on the management of nail bed injuries as a part of the complex finger tip injury and outlines the surgical principles and techniques that were used in their management...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200489/flexion-deformities-of-the-wrist-and-fingers-in-spastic-cerebral-palsy-a-protocol-of-management
#9
Tarek Hassan Abdelaziz, Shady Samir Elbeshry, Mahmoud Mahran, Ahmad Saeed Aly
Background: Literature is confusing regarding grading and treatment of flexion deformities of wrist and fingers in spastic cerebral palsy (CP). The most established classification is that described by Zancolli; unfortunately, it has its shortcomings which we experienced in the beginning of our approach to manage this rather difficult deformity. We thus modified Zancolli's classification and developed a classification system and treatment protocol. Materials and Methods: Thirty patients with spastic CP were operated upon due to flexion deformity of the wrist and fingers and were included in this study...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200488/a-newly-designed-intramedullary-nail-for-the-treatment-of-diaphyseal-forearm-fractures-in-adults
#10
Ibrahim Azboy, Abdullah Demirtaş, Celil Alemdar, Mehmet Gem, Kadir Uzel, Huseyin Arslan
Background: The treatment of diaphyseal forearm fractures using open reduction and plate fixation is generally accepted as the best choice in many studies. However, periosteal stripping, haematoma evacuation may result in delayed union, nonunion and infection. Refracture after plate removal is another concern. To overcome these problems intramedullary nails (IM) with different designs have been used with various outcomes. However previous IM nails have some shortcomings such is rotational instability and interlocking difficulties...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200487/morton-s-neuroma-interdigital-neuralgia-treated-with-metatarsal-sliding-osteotomy
#11
Joonho Lee, Jeongyo Kim, Myoungjin Lee, Intak Chu, Sungjae Lee, Heuichul Gwak
Background: Morton's neuroma is a common cause of metatarsalgia and many treatments had been described in literature. However, there have been only a few reports that treat the neuroma with an osteotomy on the proximal, not distal portion of the metatarsal bone using a plate. This study describes the clinical outcome of sliding osteotomy on the proximal metatarsal bone for the treatment of Morton's neuroma. Materials and Methods: Sixty five consecutive patients (85 feet) who underwent surgery for Morton's neuroma between November 2010 and February 2013 were identified from hospital records to include in this retrospective study...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200485/clinical-outcomes-of-an-initial-3-month-trial-of-conservative-treatment-for-femoroacetabular-impingement
#12
Aditya L Kekatpure, Taesoo Ahn, Chul-Ho Kim, Soong Joon Lee, Kang Sup Yoon, Pil Whan Yoon
Background: Femoroacetabular impingement (FAI) can be managed either conservatively or by a surgical correction of the deformity causing impingement. However, there is insufficient evidence to justify an immediate surgical treatment in all symptomatic patients, and the role of a nonoperative treatment is unclear. This study evaluates the role of conservative treatment for FAI. Materials and Methods: 87 patients (102 hips) diagnosed as FAI between January 2011 and May 2012 were included in this retrospective study...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200484/treatment-of-femoroacetabular-impingement-with-a-mini-open-direct-anterior-approach
#13
Paweł Skowronek, Marek Synder, Michał Polguj, Dariusz Marczak, Marcin Sibiński
Background: The opinion about best methods of femoroacetabular impingement (FAI) treatment are not consistent. Operative treatment of this condition may be arthroscopic, but open procedures with osteotomy of the greater trochanter and hip dislocation has been used. The present study evaluates the benefits of the mini-open direct anterior approach (DAA) in treating patients with FAI, with is a procedure available for most orthopedic surgeons. Materials and Methods: 39 patients treated for FAI (25 men and 14 women) at an average age of 29...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200482/computer-simulation-of-two-level-pedicle-subtraction-osteotomy-for-severe-thoracolumbar-kyphosis-in-ankylosing-spondylitis
#14
Ning Zhang, Hao Li, Zheng-Kuan Xu, Wei-Shan Chen, Qi-Xin Chen, Fang-Cai Li
Background: Advanced ankylosing spondylitis is often associated with thoracolumbar kyphosis, resulting in an abnormal spinopelvic balance and pelvic morphology. Different osteotomy techniques have been used to correct AS deformities, unfortunnaly, not all AS patients can gain spinal sagittal balance and good horizontal vision after osteotomy. Materials and Methods: Fourteen consecutive AS patients with severe thoracolumbar kyphosis who were treated with two-level PSO were studied retrospectively...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200481/cervical-laminectomy-with-lateral-mass-screw-fixation-in-cervical-spondylotic-myelopathy-neurological-and-sagittal-alignment-outcome-do-we-need-lateral-mass-screws-at-each-segment
#15
Manoj Dayalal Singrakhia, Nikhil Ramdas Malewar, Sonal Manoj Singrakhia, Shivaji Subhash Deshmukh
Background: Anterior cervical decompression and fusion is the standard procedure used for treating patients with cervical myelopathy. However, these procedures are associated with complications such as pseudarthrosis, construct failure, and neurological complications. Posterior cervical laminectomy and instrumentation is an alternative procedure to treat multilevel cervical myelopathy. In this study, we raised questions whether instrumentation is required at all levels and whether stabilizing the spine in neutral or lordotic contour with indirect decompression leads to neurological improvement with radiological evidence of anterior decompression...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29199720/a-prospective-randomized-trial-comparing-capecitabine-based-chemoradiotherapy-with-5-fu-based-chemoradiotherapy-in-neoadjuvant-setting-in-locally-advanced-carcinoma-rectum
#16
K Singh, M K Gupta, R K Seam, M Gupta
INTRODUCTION: Fluorouracil (FU)based chemoradiotherapy is regarded as a standard perioperative treatment in locally advanced rectal cancer. Capecitabine is an oral fluoropyrimidine that generates 5FU preferentially at the tumor site by exploiting the higher activity of the enzyme thymidine phosphorylase in tumor tissue compared with healthy tissue. As an oral agent, capecitabine can be administered in the outpatient setting, potentially providing FU exposure similar to a lowdose continuous infusion of 5FU...
January 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29197925/imaging-and-histology-in-the-diagnosis-of-multiple-papillary-fibroelastomas-in-a-patient-with-hypertrophic-obstructive-cardiomyopathy-case-report
#17
Alin Alexandru Ionescu, Bogdan Radulescu, Vlad Herlea, Ioan Miclea, Irinel Parepa, Serban Bubenek, Bogdan Alexandru Popescu, Carmen Ginghina, Ruxandra Jurcut
Papillary fibroelastomas (PFEs) are one of the most frequent primary cardiac tumors and occur more often in patients with hypertrophic obstructive cardiomyopathy (HOCM). PFEs have been linked to an increased risk of neurological events. We report a case of a 59-year-old woman with HOCM in whom echocardiography (transthoracic and transesophageal, using 2D and 3D techniques) revealed multiple masses in various locations in the left cardiac chambers. Surgical excision of the cardiac tumors and aortic valve replacement was performed and the pathologic report confirmed the diagnosis of PFEs...
November 29, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/29196385/characteristic-and-outcome-of-psoriatic-arthritis-patients-with-hyperuricemia
#18
Roa'A AlJohani, Ari Polachek, Justine Yang Ye, Vinod Chandran, Dafna D Gladman
OBJECTIVE: To determine the characteristics of patients with psoriatic arthritis (PsA) who have hyperuricemia (HUC) and their outcomes, especially cardiovascular (CVD) and kidney diseases. METHODS: Patients have been followed prospectively at the PsA clinic according to a standard protocol at 6- to 12-month intervals. We defined HUC in men > 450 μmol/l or women > 360 μmol/l. We matched patients with HUC based on sex and age ± 5 years with normal uric acid patients...
December 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29196381/sharing-ongoing-care-with-primary-care-physicians-opens-up-opportunity-for-timelier-and-earlier-care-by-rheumatologists-for-patients-with-new-inflammatory-polyarthritis
#19
Patrick Nguyen, Anne-Sophie Julien, Louis Bessette, Paul R Fortin, Laëtitia Michou
OBJECTIVE: In our region in Quebec, Canada, access to rheumatologists is very limited. Sharing followup of stable patients with their primary care physicians (PCP) could increase access to rheumatologists. In our study, we assessed the feasibility and potential benefits of sharing followup of inflammatory arthritis (IA) patients with their PCP. METHODS: We reviewed the clinical records of 300 patients with peripheral arthritis who presented at our rheumatology outpatient clinic between July and October 2015...
December 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29193197/signaling-profiles-of-blood-leukocytes-in-sepsis-and-in-acute-pancreatitis-in-relation-to-disease-severity
#20
Krista Kuuliala, Anne K Penttilä, Kirsi-Maija Kaukonen, Harri Mustonen, Antti Kuuliala, Jani Oiva, Mari Hämäläinen, Eeva Moilanen, Ville Pettilä, Pauli Puolakkainen, Leena Kylänpää, Heikki Repo
Intracellular signaling in blood leukocytes shows multiple aberrations in acute pancreatitis (AP) complicated by organ dysfunction (OD). We studied whether the aberrations associate with severity of AP and occur in sepsis complicated by OD. Study comprises 14 sepsis patients (11 with shock), 18 AP patients (9 mild; 6 moderately severe; 3 severe), and 28 healthy volunteers. Within 48 hours after admission to hospital, phosphorylation of nuclear factor-ĸB (NF-ĸB), signal transducers and activators of transcription (STATs) 1,3, and extracellular signal-regulated kinases 1/2 was measured from stimulated or non-stimulated leukocytes using phosphospecific whole blood flow cytometry...
November 29, 2017: Scandinavian Journal of Immunology
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