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https://www.readbyqxmd.com/read/29664125/formal-sacrocolpopexy-reduces-hypercontinence-rates-in-female-neobladder-formation
#1
Gillian Stearns, Timothy Donahue, Ali Fathollahi, Guido Dalbagni, Jaspreet Sandhu
AIMS: Continent urinary diversion is preferred by some patients and orthotopic urinary diversion (OUD) has become the procedure of choice for most men following cystectomy for invasive bladder cancer. OUD in women, however, is less common, likely due to a high rate of hypercontinence (HC), potentially from lax support of pelvic structures similar to pelvic organ prolapse. As such, we evaluated if abdominal sacrocolpopexy (ASC) at the time of OUD in women led to decreased rates of HC. METHODS: A retrospective review of all female patients receiving OUD by a single surgeon and ASC was performed...
April 17, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29657479/minimally-invasive-mis-t%C3%A3-nnis-osteotomy-a-technical-annotation-and-review-of-short-term-results
#2
Balasubramanian Balakumar, Malek Racy, Sanjeev Madan
Aims: We detail a modified single incision approach to perform the Tonnis triple pelvic osteotomy by a minimally invasive approach. Patients and Methods: 12 children underwent minimally invasive Tonnis Osteotomy. There were five boys and seven girls in this study group. Average age was 11 years (9-15 years) at the time of surgery. Mean follow-up was 20.5 months (13-39 months). Results: The average preoperative Antero-Posterior (AP) Centre Edge (CE) angle was -8...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29657153/repeat-testing-of-antibodies-and-complements-in-systemic-lupus-erythematosus-when-is-it-enough
#3
Thomas C Raissi, Carly Hewson, Janet E Pope
OBJECTIVE: Patients with systemic lupus erythematosus (SLE) frequently undergo repeat testing for antibodies against extractable nuclear antigens (anti-ENA), but it is not known whether this is necessary or cost-effective. This study characterized the frequencies of changes in anti-ENA, anti-dsDNA, and complement C3 and C4 upon repeat testing. METHODS: Chart review was done at one site of 130 patients with SLE enrolled in the 1000 Canadian Faces of Lupus prospective registry with annual antibody and complement testing...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29657149/the-natural-course-of-diffuse-idiopathic-skeletal-hyperostosis-in-the-thoracic-spine-of-adult-males
#4
Jonneke S Kuperus, Constantinus F Buckens, Jurica Šprem, F Cumhur Oner, Pim A de Jong, Jorrit-Jan Verlaan
OBJECTIVE: Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by flowing bony bridges on the right side of the spine. Knowledge of the development of these spinal bridges is limited. The current longitudinal computed tomography (CT) study was designed to bridge this gap. METHODS: Chest CT scans from elderly males with 2 scans (interval ≥ 2.5 yrs) were retrospectively included. Using the Resnick criteria, a pre-DISH group and a definite DISH group were identified...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29657144/macrophage-activation-syndrome-in-patients-affected-by-adult-onset-still-disease-analysis-of-survival-rates-and-predictive-factors-in-the-gruppo-italiano-di-ricerca-in-reumatologia-clinica-e-sperimentale-cohort
#5
Piero Ruscitti, Daniela Iacono, Francesco Ciccia, Giacomo Emmi, Paola Cipriani, Rosa Daniela Grembiale, Federico Perosa, Lorenzo Emmi, Giovanni Triolo, Roberto Giacomelli, Gabriele Valentini
OBJECTIVE: Macrophage activation syndrome (MAS) is a reactive form of hemophagocytic lymphohistiocytosis, which can complicate adult-onset Still disease (AOSD). We investigated AOSD clinical features at the time of diagnosis, to assess predictors of MAS occurrence. Further, we analyzed the outcomes of patients with AOSD who experience MAS. METHODS: Patients with AOSD admitted to any Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale center were retrospectively analyzed for features typical of AOSD, MAS occurrence, and their survival rate...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29657143/clinical-and-serological-associations-with-the-development-of-incident-proteinuria-in-danish-patients-with-systemic-lupus-erythematosus
#6
Nima Tanha, Renata Baronaite Hansen, Christoffer Tandrup Nielsen, Mikkel Faurschou, Søren Jacobsen
OBJECTIVE: In a longitudinal cohort study, we investigated whether clinical and serological manifestations at the time of classification of systemic lupus erythematosus (SLE) were predictive of subsequent development of incident proteinuria as a biomarker of incident lupus nephritis. METHODS: Patients fulfilling SLE classification criteria but having no proteinuria prior to or at the time of classification were included. Data on SLE manifestations, vital status, criteria-related autoantibodies, and SLE-associated medications were collected during clinical visits and supplemented by chart review...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29657140/longterm-safety-and-efficacy-of-adalimumab-and-infliximab-for-uveitis-associated-with-juvenile-idiopathic-arthritis
#7
Vanessa Cecchin, Maria Elisabetta Zannin, Daniele Ferrari, Irene Pontikaki, Elisabetta Miserocchi, Maria P Paroli, Claudia Bracaglia, Denise Pires Marafon, Serena Pastore, Fulvio Parentin, Gabriele Simonini, Cinzia De Libero, Fernanda Falcini, Antonella Petaccia, Giovanni Filocamo, Riccardo De Marco, Francesco La Torre, Silvana Guerriero, Silvana Martino, Francesco Comacchio, Valentina Muratore, Giorgia Martini, Fabio Vittadello, Francesco Zulian
OBJECTIVE: Anti-TNF-α agents have significantly changed the management of juvenile idiopathic arthritis (JIA). We evaluated the safety and efficacy of adalimumab (ADA) and infliximab (IFX) for the treatment of JIA-associated uveitis in patients treated for ≥ 2 years. METHODS: Patients with JIA-associated uveitis treated with IFX and ADA were managed by a standardized protocol and data were entered in the ORCHIDEA registry. At baseline, all patients were refractory to standard immunosuppressive treatment or were corticosteroid-dependent...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29651167/constraining-relativistic-bow-shock-properties-in-rotation-powered-millisecond-pulsar-binaries
#8
Zorawar Wadiasingh, Alice K Harding, Christo Venter, Markus Böttcher, Matthew G Baring
Multiwavelength followup of unidentified Fermi sources has vastly expanded the number of known galactic-field "black widow" and "redback" millisecond pulsar binaries. Focusing on their rotation-powered state, we interpret the radio to X-ray phenomenology in a consistent framework. We advocate the existence of two distinct modes differing in their intrabinary shock orientation, distinguished by the phase-centering of the double-peaked X-ray orbital modulation originating from mildly-relativistic Doppler boosting...
April 20, 2017: Astrophysical Journal
https://www.readbyqxmd.com/read/29616149/immersive-virtual-reality-therapy-with-myoelectric-control-for-treatment-resistant-phantom-limb-pain-case-report
#9
Brian Chau, Ivan Phelan, Phillip Ta, Sarah Humbert, Justin Hata, Duc Tran
Objective: Phantom limb pain is a condition frequently experienced after amputation. One treatment for phantom limb pain is traditional mirror therapy, yet some patients do not respond to this intervention, and immersive virtual reality mirror therapy offers some potential advantages. We report the case of a patient with severe phantom limb pain following an upper limb amputation and successful treatment with therapy in a custom virtual reality environment. Methods: An interactive 3-D kitchen environment was developed based on the principles of mirror therapy to allow for control of virtual hands while wearing a motion-tracked, head-mounted virtual reality display...
July 2017: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/29606669/flares-of-disease-in-children-with-clinically-inactive-juvenile-idiopathic-arthritis-were-not-correlated-with-ultrasound-findings
#10
Yongdong Zhao, Nanci E Rascoff, Ramesh S Iyer, Mahesh Thapa, Lucas Reichley, Assaf P Oron, Carol A Wallace
OBJECTIVE: The validity of our current definitions for clinically inactive disease (CID) in juvenile idiopathic arthritis (JIA) based on physical examination is challenged by the development of advanced musculoskeletal imaging tools. We aimed to prospectively determine the prevalence of abnormal ultrasound (US) findings in children with CID in JIA and their clinical significance. METHODS: Children aged ≥ 4 years with CID and a history of arthritis from a single tertiary center were approached over 1 year...
April 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29606666/comparative-analysis-and-predictors-of-10-year-tumor-necrosis-factor-inhibitors-drug-survival-in-patients-with-spondyloarthritis-first-year-response-predicts-longterm-drug-persistence
#11
Irini D Flouri, Theodora E Markatseli, Kyriaki A Boki, Ioannis Papadopoulos, Fotini N Skopouli, Paraskevi V Voulgari, Loukas Settas, Dimitrios Zisopoulos, Alexios Iliopoulos, Pierre Geborek, Alexandros A Drosos, Dimitrios T Boumpas, Prodromos Sidiropoulos
OBJECTIVE: To evaluate the 10-year drug survival of the first tumor necrosis factor inhibitor (TNFi) administered to patients with spondyloarthritis (SpA) overall and comparatively between SpA subsets, and to identify predictors of drug retention. METHODS: Patients with SpA in the Hellenic Registry of Biologic Therapies, a prospective multicenter observational cohort, starting their first TNFi between 2004-2014 were analyzed. Kaplan-Meier curves and Cox regression models were used...
April 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29603920/the-role-of-neutrophil-lymphocyte-ratio-as-a-prognostic-indicator-in-patients-undergoing-nephrectomy-for-renal-cell-carcinoma
#12
Nathan Grimes, Cathal Hannan, Matthew Tyson, Ali Thwaini
INTRODUCTION: Prognosis in patients with cancer is influenced by underlying tumour biology and also the host inflammatory response to the disease. There is limited evidence to suggest that an elevated neutrophil-lymphocyte ratio (NLR) predicts a poorer prognosis in patients undergoing nephrectomy for renal cell carcinoma (RCC). The aim of this paper is to investigate if patients undergoing nephrectomy for RCC with NLR ≤4 have a better overall and recurrence-free survival than patients with NLR >4...
March 19, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29603915/examining-the-association-between-adiposity-and-biochemical-recurrence-after-radical-prostatectomy
#13
Ross J Mason, Stephen A Boorjian, Bimal Bhindi, Laureano Rangel, Igor Frank, R Jeffrey Karnes, Matthew K Tollefson
INTRODUCTION: Herein we examined the association between adiposity, as measured with computed tomography (CT), and biochemical recurrence (BCR) after RP. METHODS: Using axial CT images, preoperative fat mass index (FMI) was calculated for 698 men who underwent RP from 2007-2010 by using measurements of total surface area of adipose tissue at the L3 level. Obesity was classified according to NHANES standards for obesity (FMI >9 kg/m2 ). The associations between obesity and the distribution of adiposity (visceral vs...
March 19, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29603912/photoselective-vaporization-of-the-prostate-with-the-180-w-xps-greenlight-laser-five-year-experience-of-safety-efficiency-and-functional-outcomes
#14
Khaled Ajib, Mila Mansour, Marc Zanaty, Mansour Alnazari, Pierre-Alain Hueber, Malek Meskawi, Roger Valdivieso, Come Tholomier, Benjamin Pradere, Vincent Misrai, Dean Elterman, Kevin C Zorn
INTRODUCTION: Transurethral resection of the prostate (TURP) is still considered the gold standard surgical treatment for symptomatic benign prostatic hyperplasia (BPH). However, photoselective vaporization of the prostate (PVP) has gained widespread global acceptance in national guidelines as a safe and effective alternative option. Nevertheless, further evidence is required to assess the durability of Greenlight PVP. Herein, we reported our five years PVP experience with the Greenlight 180W XPS laser system...
March 19, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29603272/thoracic-versus-non-thoracic-mr-imaging-for-patients-with-an-mr-non-conditional-cardiac-implantable-electronic-device
#15
Iwan S Nyotowidjojo, Kristina Skinner, Aakash S Shah, Jaskinwal Bisla, Satinder Singh, Rostam Khoubyari, Peter Ott, Bobby Kalb, Julia H Indik
BACKGROUND: Observational studies have explored the safety of magnetic resonance (MR) scanning of patients with cardiac implantable electronic devices (CIEDs) that are not FDA approved for MR scanning ("non-conditional"). However, concern has been raised that MR scanning that includes the thoracic region may pose a higher risk. This study examines the safety of MR scanning of thoracic versus non-thoracic regions of patients with CIEDs. METHODS: Patients underwent MR scanning utilizing an institutional protocol...
March 30, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29601384/are-age-and-patient-gender-associated-with-different-rates-and-magnitudes-of-clinical-improvement-after-reverse-shoulder-arthroplasty
#16
Richard J Friedman, Emilie V Cheung, Pierre-Henri Flurin, Thomas Wright, Ryan W Simovitch, Charlotte Bolch, Christopher P Roche, Joseph D Zuckerman
BACKGROUND: An improved understanding of how gender differences and the natural aging process are associated with differences in clinical improvement in outcome metric scores and ROM measurements after reverse total shoulder arthroplasty (rTSA) may help physicians establish more accurate patient expectations for reducing postoperative pain and improving function. QUESTIONS/PURPOSES: (1) Is gender associated with differences in rTSA outcome scores like the Simple Shoulder Test (SST), the UCLA Shoulder score, the American Shoulder and Elbow Surgeons (ASES) Shoulder score, the Constant Shoulder score, and the Shoulder Pain and Disability Index (SPADI) and ROM? (2) Is age associated with differences in rTSA outcome scores and ROM? (3) What factors are associated with the combined interaction effect between age and gender? (4) At what time point during recovery does most clinical improvement occur, and when is full improvement reached? METHODS: We quantified and analyzed the outcomes of 660 patients (424 women and 236 men; average age, 72 ± 8 years; range, 43-95 years) with cuff tear arthropathy or osteoarthritis and rotator cuff tear who were treated with rTSA by 13 shoulder surgeons from a longitudinally maintained international database using a linear mixed effects statistical model to evaluate the relationship between clinical improvements and gender and patient age...
March 28, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29601379/moderate-to-severe-renal-insufficiency-is-associated-with-high-mortality-after-hip-and-knee-replacement
#17
Pyry Jämsä, Esa Jämsen, Heini Huhtala, Antti Eskelinen, Niku Oksala
BACKGROUND: In patients having elective hip or knee replacements, many comorbid conditions, including diabetes, cardiovascular disease, and congestive heart failure, are associated with postoperative mortality. Renal failure and a history of renal transplantation also increase mortality. However, the effect of different stages of chronic kidney disease on patients' prognoses is unclear. QUESTIONS/PURPOSES: (1) What is the risk of postoperative mortality in different stages of chronic kidney disease after elective hip or knee replacement and does the risk increase with mild renal insufficiency? (2) How severe is the risk of death in patients with chronic kidney disease compared with other major medical comorbidities such as diabetes, cardiovascular disease, and congestive heart failure? (3) Are there risk factor combinations associated with especially poor survival? METHODS: Using longitudinally maintained databases, the records of 18,575 patients (median age 69 years, 63% female, median body mass index 29 kg/m) undergoing elective hip and knee replacements from a single center between 2002 and 2011 were analyzed in this retrospective study...
March 28, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29601378/is-anesthesia-technique-associated-with-a-higher-risk-of-mortality-or-complications-within-90-days-of-surgery-for-geriatric-patients-with-hip-fractures
#18
Vimal Desai, Priscilla H Chan, Heather A Prentice, Gary L Zohman, Glenn R Diekmann, Gregory B Maletis, Brian H Fasig, Diana Diaz, Elena Chung, Chunyuan Qiu
BACKGROUND: Postoperative mortality and complications after geriatric hip fracture surgery remain high despite efforts to improve perioperative care for these patients. One factor of particular interest is anesthetic technique, but prior studies on this are limited by sample selection, competing risks, and incomplete followup. QUESTIONS/PURPOSES: (1) Among older patients undergoing surgery for hip fracture, does 90-day mortality differ depending on the type of anesthesia received? (2) Do 90-day emergency department returns and hospital readmissions differ based on anesthetic technique after geriatric hip fracture repairs? (3) Do 90-day Agency for Healthcare Research and Quality (AHRQ) outcomes differ according to anesthetic techniques used during hip fracture surgery? METHODS: We conducted a retrospective study on geriatric patients (65 years or older) with hip fractures between 2009 and 2014 using the Kaiser Permanente Hip Fracture Registry...
March 28, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29600794/fluid-collection-after-partial-pancreatectomy-eus-drainage-and-long-term-follow-up
#19
Fabrice Caillol, Sebastien Godat, Olivier Turrini, Christophe Zemmour, Erwan Bories, Christian Pesenti, Jean Phillippe Ratone, Jacques Ewald, Jean Robert Delpero, Marc Giovannini
Background and Objectives: Postoperative fluid collection due to pancreatic leak is the most frequent complication after pancreatic surgery. Endoscopic ultrasound (EUS)-guided drainage of post-pancreatic surgery fluid collection is the gold standard procedure; however, data on outcomes of this procedure are limited. The primary endpoint of our study was relapse over longterm followup, and the secondary endpoint was the efficiency and safety of EUS-guided drainage of post-pancreatic surgery fluid collection...
March 29, 2018: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/29596724/a-randomized-controlled-trial-of-a-gender-focused-addiction-model-versus-12-step-facilitation-for-women-veterans
#20
Lisa M Najavits, Justin Enggasser, Deborah Brief, Edward Federman
BACKGROUND AND OBJECTIVES: Substance use disorder (SUD) has increased among women, including military veterans, yet SUD treatment was historically designed for males. This randomized controlled trial compared 12 individual sessions of a gender-focused SUD recovery model, A Woman's Path to Recovery (WPR) to an evidence-based, non-gender-focused SUD model, 12-Step Facilitation (TSF) for 66 women veterans with current severe SUD. METHODS: The primary outcome was substance use; secondary outcomes were associated problems (e...
April 2018: American Journal on Addictions
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