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https://www.readbyqxmd.com/read/28230451/positive-medication-changes-resulting-from-comprehensive-and-noncomprehensive-medication-reviews-in-a-medicare-part-d-population
#1
Allison Buhl, Jill Augustine, Ann M Taylor, Rose Martin, Terri L Warholak
BACKGROUND: Health care organizations face the challenge of reducing costs while improving health outcomes. Currently, more than 39 million seniors are enrolled in a Medicare Part D prescription benefit plan, many of whom also qualify for medication therapy management (MTM) services. MTM programs provide valuable services designed to prevent or resolve medication-related problems (MRPs). Two core components of all MTM programs include comprehensive medication reviews (CMRs) with followup interventions and focused non-CMR interventions...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28225542/historical-overview-of-leprosy-control-in-cuba
#2
Enrique Beldarraín-Chaple
INTRODUCTION Leprosy, an infectious disease caused by Mycobacterium leprae, affects the nervous system, skin, internal organs, extremities and mucous membranes. Biological, social and environmental factors influence its occurrence and transmission. The first effective treatments appeared in 1930 with the development of dapsone, a sulfone. The main components of a control and elimination strategy are early case detection and timely administration of multidrug therapy. OBJECTIVES Review the history of leprosy control in Cuba, emphasizing particularly results of the National Leprosy Control Program, its modifications and influence on leprosy control...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28224442/report-of-the-primary-outcomes-for-gait-mechanics-in-men-of-the-acl-sports-trial-secondary-prevention-with-and-without-perturbation-training-does-not-restore-gait-symmetry-in-men-1-or-2-years-after-acl-reconstruction
#3
Jacob John Capin, Ryan Zarzycki, Amelia Arundale, Kathleen Cummer, Lynn Snyder-Mackler
BACKGROUND: Movement asymmetries during walking are common after anterior cruciate ligament (ACL) injury and reconstruction and may influence the early development of posttraumatic osteoarthritis. Preoperative neuromuscular training (like perturbation training, which is neuromuscular training requiring selective muscle activation in response to surface perturbations) improves gait asymmetries and functional outcomes among people who are ACL-deficient, but the effect of postoperative perturbation training on gait mechanics after ACL reconstruction is unknown...
February 21, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28222973/nationwide-multi-institutional-retrospective-analysis-of-high-dose-rate-brachytherapy-combined-with-external-beam-radiotherapy-for-localized-prostate-cancer-an-asian-prostate-hdr-bt-consortium
#4
Hiromichi Ishiyama, Nobuhiko Kamitani, Hidemasa Kawamura, Shingo Kato, Manabu Aoki, Shinji Kariya, Taisei Matsumura, Motoki Kaidu, Ken Yoshida, Yaichiro Hashimoto, Yasutaka Noda, Keith H C Lim, Takatsugu Kawase, Takeo Takahashi, Koji Inaba, Motoyasu Kumano, Nobuhiko Yoshikawa, Yasuo Yoshioka, Katsumasa Nakamura, Junichi Hiratsuka, Jun Itami, Kazushige Hayakawa
PURPOSE: To report outcomes and risk factors of high-dose-rate (HDR) brachytherapy combined with external beam radiotherapy with or without androgen deprivation therapy (ADT) in prostate cancer patients. MATERIALS AND METHODS: This multi-institutional retrospective analysis comprised 3424 patients with localized prostate cancer at 16 Asian hospitals. One-thirds (27.7%) of patients received only neoadjuvant ADT, whereas almost half (49.5%) of patients received both neoadjuvant and adjuvant ADT...
February 17, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28217989/comparison-of-endovenous-radiofrequency-ablation-laser-ablation-foam-sclerotherapy-and-surgical-stripping-for-great-saphenous-varicose-veins-extended-5-year-follow-up-of-a-rct
#5
Martin Lawaetz, Julie Serup, Birgit Lawaetz, Lars Bjoern, Allan Blemings, Bo Eklof, Lars Rasmussen
BACKGROUND: This study compares the outcome 5 years after treatment of varicose veins with endovenous radiofrequency ablation (RFA), endovenous laser ablation (EVLA), ultrasound guided foam sclerotherapy (UGFS) or high ligation and stripping (HL/S) by assessing technical efficacy, clinical recurrence and the rate of reoperations. METHODS: Five hundred patients (580 legs) with Great Saphenous Vein (GSV) reflux and varicose veins were randomized to one of the 4 treatments...
February 17, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28216758/-quadrangular-construct-modification-of-sauve-kapandji-procedure
#6
Ravi K Gupta, Ashwani Soni, Anubhav Malhotra, Gladson D Masih
BACKGROUND: Subluxation of ulna in distal radioulnar joint disorders causes pain on motion, loss of grip strength, and a restriction of forearm rotation. Several procedures have been described to salvage DRUJ disorders including the Darrach procedure, the matched distal ulnar resection, the hemiresection interposition arthroplasty (Bowers procedure) and the Sauve-Kapandji (S-K) procedure. All these procedures are associated with either loss of grip, pain over proximal ulnar stump or instability...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28216757/distal-radius-fractures-minimally-invasive-plate-osteosynthesis-with-dorsal-bicolumnar-locking-plates-fixation
#7
Alvin Chao-Yu Chen, Ying-Chao Chou, Chun-Ying Cheng
BACKGROUND: Controversy still exists regarding the current treatment modalities for unstable distal radius fractures. There are yet few articles investigating the efficacy of bicolumnar dorsal plating technique, which is designed to minimize tissue dissection while providing sufficiently secure fixation. A clinical study was performed to evaluate the feasibility of the minimally invasive plate osteosynthesis (MIPO) technique using a modified dorsal approach for the treatment of distal radius fractures...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28216756/outcome-of-anatomic-locking-plate-in-extraarticular-distal-humeral-shaft-fractures
#8
Deepak Jain, Gurpreet S Goyal, Rajnish Garg, Pankaj Mahindra, Mohammad Yamin, Harpal S Selhi
BACKGROUND: Extraarticular fractures of distal humerus are challenging injuries to treat because of complex anatomy and fracture patterns. Functional bracing may not provide adequate stability in these injuries and operative treatment with intramedullary nails or conventional plates also has the limitation of inadequate fixation in the short distal fragment. The 3.5 mm precontoured single column locking plate (extraarticular distal humerus plate [EADHP]) has been introduced to overcome this problem...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28216754/transfibular-ankle-arthrodesis-a-novel-method-for-ankle-fusion-a-short-term-retrospective-study
#9
S Muthukumar Balaji, V Selvaraj, Sathish Devadoss, Annamalai Devadoss
BACKGROUND: Ankle arthrodesis has long been the traditional operative treatment for posttraumatic arthritis, rheumatoid arthritis, infection, neuromuscular conditions, and salvage of failed ankle arthroplasty. It remains the treatment of choice for patients in whom heavy and prolonged activity is anticipated. We present our short term followup study of functional outcome of patients who underwent transfibular ankle arthrodesis for arthritis of ankle due to various indications. MATERIALS AND METHODS: 29 transfibular ankle arthrodesis in 29 patients performed between April 2009 and April 2014 were included in this study...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28216749/percutaneous-endoscopic-lumbar-discectomy-results-of-first-100-cases
#10
Kanthila Mahesha
BACKGROUND: Lumbar disc herniation is a major cause of back pain and sciatica. The surgical management of lumbar disc prolapse has evolved from exploratory laminectomy to percutaneous endoscopic discectomy. Percutaneous endoscopic discectomy is the least invasive procedure for lumbar disc prolapse. The aim of this study was to analyze the clinical outcome, quality of life, neurologic function, and complications. MATERIALS AND METHODS: One hundred patients with lumbar disc prolapse who were treated with percutaneous endoscopic discectomy from May 2012 to January 2014 were included in this retrospective study...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28216747/complex-ao-type-c3-distal-femur-fractures-results-after-fixation-with-a-lateral-locked-plate-using-modified-swashbuckler-approach
#11
Anuj Agrawal, Vivek Kiyawat
BACKGROUND: Complex AO type C3 fractures of the distal femur are challenging injuries, fraught with complications such as malunion and stiffness. We prospectively evaluated a consecutive series of patients with complex AO type C3 distal femur fractures to determine the clinicoradiological outcome after fixation with a single locked plate using modified swashbuckler approach. MATERIALS AND METHODS: 12 patients with C3 type distal femur fractures treated with a lateral locked plate, using a modified swashbuckler approach, were included in the study...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28215846/active-surveillance-is-superior-to-radical-nephrectomy-and-equivalent-to-partial-nephrectomy-for-preserving-renal-function-in-patients-with-small-renal-masses-results-from-the-dissrm-registry
#12
M R Danzig, R A Ghandour, P Chang, A A Wagner, P M Pierorazio, M E Allaf, J M McKiernan
PURPOSE: We compared renal function outcomes among patients in the surveillance and intervention arms of the DISSRM registry. MATERIALS AND METHODS: Patients were grouped into chronic kidney disease stages by estimated glomerular filtration rate range. Cases were considered up staged if a more advanced chronic kidney disease stage was entered during followup. Chronic kidney disease up staging-free survival was compared among groups using Kaplan-Meier analysis and paired comparisons log rank tests...
March 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28214570/routine-urethrograpy-after-buccal-graft-bulbar-urethroplasty-the-impact-of-initial-urethral-leak-on-surgical-success
#13
Erik T Grossgold, Jairam R Eswara, Cary L Siegel, Joel Vetter, Steven B Brandes
OBJECTIVE: To determine the long-term impact of extravasation at initial post-urethroplasty urethrogram, we present a novel classification system and report the association of leak severity with outcome. MATERIALS AND METHODS: 91 patients underwent buccal graft urethroplasties of the bulbar urethra from 2007-2015. Median time to urethrogram was 23d. All leaks were characterized by length and width. Cutoffs for length and width were calculated using ROC curves. Each urethrogram was graded 0-3 (0=no leak) with one point given for any leak, length ≥1...
February 15, 2017: Urology
https://www.readbyqxmd.com/read/28212789/laboratory-diagnosis-of-echinococcus-spp-in-human-patients-and-infected-animals
#14
M Siles-Lucas, A Casulli, F J Conraths, N Müller
Among the species composing the genus Echinococcus, four species are of human clinical interest. The most prevalent species are Echinococcus granulosus and Echinococcus multilocularis, followed by Echinococcus vogeli and Echinococcus oligarthrus. The first two species cause cystic echinococcosis (CE) and alveolar echinococcosis (AE) respectively. Both diseases have a complex clinical management, in which laboratory diagnosis could be an adjunctive to the imaging techniques. To date, several approaches have been described for the laboratory diagnosis and followup of CE and AE, including antibody, antigen and cytokine detection...
2017: Advances in Parasitology
https://www.readbyqxmd.com/read/28205473/functional-outcomes-of-antegrade-homodigital-neurovascular-island-flaps-for-fingertip-amputation
#15
Lin-Wing Lok, Wing-Leung Chan, Yan-Kit Lau
BACKGROUND: Fingertip amputations can be debilitating and challenging to treat, due to the need for both function and cosmesis. We studied the functional outcomes of patients receiving an antegrade homodigital neurovascular island flap for fingertip amputations. METHODS: From 2004 to 2013, we performed 13 cases of antegrade homodigital neurovascular island flaps. Functional outcomes were studied. Four had Allen Zone II and nine had Zone III injuries. Seven were performed as secondary surgery...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28205075/hamstring-autograft-versus-patellar-tendon-autograft-for-acl-reconstruction-is-there-a-difference-in-graft-failure-rate-a-meta-analysis-of-47-613-patients
#16
Brian T Samuelsen, Kate E Webster, Nick R Johnson, Timothy E Hewett, Aaron J Krych
BACKGROUND: Bone-patellar tendon-bone (bone-tendon-bone) and four-strand hamstring tendon grafts (hamstring) are the most commonly utilized autografts for primary anterior cruciate ligament (ACL) reconstruction. Existing clinical trials, registry studies, and meta-analyses offer conflicting opinions regarding the most favorable graft choice. QUESTIONS/PURPOSES: Which graft type for ACL reconstruction (bone-tendon-bone or hamstring) has a higher risk of (1) graft rupture and/or (2) graft laxity? METHODS: We performed a meta-analysis of randomized controlled trials (RCTs), prospective cohort studies, and high-quality national registry studies to compare the outcomes of primary ACL reconstruction with bone-tendon-bone autograft or hamstring autograft...
February 15, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28202746/methodological-quality-of-studies-of-endstage-renal-disease-in-lupus-nephritis-1970-to-2015
#17
Maria G Tektonidou, Michael M Ward
OBJECTIVE: To examine trends in methodological quality of studies of endstage renal disease risk in lupus nephritis, 1970-2015. METHODS: We assessed quality using the Newcastle-Ottawa scale for observational studies, and the Cochrane Collaboration's risk-of-bias tool for trials. RESULTS: In observational studies, description of enrollment criteria was high but decreased over time. Adequacy of followup was low but improved. Inception cohorts and community-based studies were uncommon...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28202741/seasonal-influence-on-the-risk-of-relapse-at-a-rise-of-antineutrophil-cytoplasmic-antibodies-in-vasculitis-patients-with-renal-involvement
#18
Michael J Kemna, Jan Willem Cohen Tervaert, Kelly Broen, Sjoerd A M E G Timmermans, Pieter van Paassen, Jan G M C Damoiseaux
OBJECTIVE: The objective of this study was to identify risk factors for a relapse at the time of an increase in antineutrophil cytoplasmic antibodies (ANCA) in patients with renal ANCA-associated vasculitis (AAV). METHODS: All patients between January 2000 and November 2011 with renal AAV having an ANCA rise during remission were included. Differences in time to relapse since the ANCA rise were assessed using a Cox regression model. The level of 25-hydroxy Vitamin D (25(OH)D) was assessed at the ANCA rise and at a subsequent relapse or time-matched during remission...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28202738/longterm-outcomes-of-renal-artery-involvement-in-takayasu-arteritis
#19
Seokchan Hong, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo
OBJECTIVE: Takayasu arteritis (TA) involving the renal artery can result in hypertension (HTN), renal dysfunction, and premature death. The aim of this study was to investigate the longterm outcomes and factors that predict outcomes in patients with TA with renal artery stenosis. METHODS: The medical records of patients diagnosed with TA between January 1997 and December 2014 were reviewed retrospectively. Renal artery involvement was based on computed tomography and/or angiography findings...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28202343/endobronchial-brachytherapy-for-metastasis-from-extrapulmonary-malignancies-as-an-effective-treatment-for-palliation-of-symptoms
#20
E Donovan, E Timotin, T Farrell, B Donde, S Puksa, R Sur
PURPOSE: Endobronchial metastasis (EBM) originating from primary cancers outside the lung is rare. External beam radiotherapy is often attempted for control of symptoms with variable effectiveness and retreatment is challenging if symptoms recur. There is limited documentation of high-dose-rate brachytherapy for EBM in the literature. METHODS AND MATERIALS: A prospective database was created from 2006 to 2015. Patients with EBM who received high-dose-rate brachytherapy were included...
February 12, 2017: Brachytherapy
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