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https://www.readbyqxmd.com/read/29456439/parent-training-and-skill-acquisition-and-utilization-among-spanish-and-english-speaking-latino-families
#1
Giovanni Ramos, Angela M Blizzard, Nicole E Barroso, Daniel M Bagner
In the U.S., there is a growing Latino population, in which parents primarily speak Spanish to their children. Despite the evidence that language preference is associated with level of acculturation and influences parenting practices in these families, no study has compared how Spanish-and English-speaking Latino families acquire and utilize the skills taught during parent-training programs such as Parent-Child Interaction Therapy (PCIT). Twenty-seven mother-infant Latino dyads received a home-based adaptation of the Child-Directed Interaction (CDI) phase of PCIT as part of a larger randomized control trial...
January 2018: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/29453603/repeatable-and-reproducible-measurements-of-myocardial-oxidative-metabolism-blood-flow-and-external-efficiency-using-11-c-acetate-pet
#2
Kai Yi Wu, Vincent Dinculescu, Jennifer M Renaud, Shin-Yee Chen, Ian G Burwash, Lisa M Mielniczuk, Rob S B Beanlands, Robert A deKemp
BACKGROUND: Non-invasive approaches to investigate myocardial efficiency can help track the progression of heart failure (HF). This study evaluates the repeatability and reproducibility of 11 C-acetate positron emission tomography (PET) imaging of oxidative metabolism. METHODS AND RESULTS: Dynamic 11 C-acetate PET scans were performed at baseline and followup (47 ± 22 days apart) in 20 patients with stable HF with reduced ejection fraction. Two observers blinded to patients' clinical data used FlowQuant ® to evaluate test-retest repeatability, as well as intra- and inter-observer reproducibility of 11 C-acetate tracer uptake and clearance rates, for the measurement of myocardial oxygen consumption (MVO 2 ), myocardial external efficiency (MEE), work metabolic index (WMI), and myocardial blood flow...
February 16, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29449506/whole-body-magnetic-resonance-imaging-in-axial-spondyloarthritis-reduction-of-sacroiliac-spinal-and-entheseal-inflammation-in-a-placebo-controlled-trial-of-adalimumab
#3
Simon Krabbe, Mikkel Østergaard, Iris Eshed, Inge J Sørensen, Bente Jensen, Jakob M Møller, Lone Balding, Ole R Madsen, Karsten Asmussen, Grith Eng, Niklas R Jørgensen, Susanne J Pedersen
OBJECTIVE: To investigate whether adalimumab (ADA) reduces whole-body (WB-) magnetic resonance imaging (MRI) indices for inflammation in the entheses, peripheral joints, sacroiliac joints, spine, and the entire body in patients with axial spondyloarthritis (axSpA). METHODS: An investigator-initiated, randomized, placebo-controlled, double-blinded 48-week followup trial included 49 patients with axSpA, who had Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) ≥ 4...
February 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29449503/early-renin-angiotensin-system-blockade-improved-short-term-and-longterm-renal-outcomes-in-systemic-lupus-erythematosus-patients-with-antiphospholipid-associated-nephropathy
#4
Cai Yue, Guanhong Li, Yubing Wen, Xuemei Li, Ruitong Gao
OBJECTIVE: To investigate the renal protective effects of early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN). METHODS: Medical data of 57 SLE patients with biopsy-proven aPLN were analyzed. Early RAAS blockade was defined as administration of RASI within 3 months after kidney biopsy and continued for ≥ 12 months...
February 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29449499/clinical-correlates-outcomes-and-predictors-of-inflammatory-ocular-disease-associated-with-rheumatoid-arthritis-in-the-biologic-era
#5
Cristian Caimmi, Cynthia S Crowson, Wendy M Smith, Eric L Matteson, Ashima Makol
OBJECTIVE: Inflammatory ocular disease (IOD) is a rare but severe extraarticular manifestation of rheumatoid arthritis (ExRA) with high mortality. The aim of our study was to examine clinical characteristics of IOD in rheumatoid arthritis (RA) and their effect on disease severity and outcomes in recent years. METHODS: A retrospective cohort of RA patients with IOD evaluated between 1996 and 2013 was assembled and compared to RA comparators without IOD and matched for age, sex, and disease duration...
February 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29443850/does-an-algorithmic-approach-to-using-brachytherapy-and-external-beam-radiation-result-in-good-function-local-control-rates-and-low-morbidity-in-patients-with-extremity-soft-tissue-sarcoma
#6
Jason Klein, Alex Ghasem, Samuel Huntley, Nathan Donaldson, Martin Keisch, Sheila Conway
BACKGROUND: High-dose-rate brachytherapy (HDR-BT) and external-beam radiation therapy (EBRT) are two modalities used in the treatment of soft tissue sarcoma. Previous work at our institution showed early complications and outcomes for patients treated with HDR-BT, EBRT, or a combination of both radiation therapy modalities. As the general indications for each of these approaches to radiation therapy differ, it is important to evaluate the use of each in an algorithmic way, reflecting how they are used in contemporary practice at sites that use these treatments...
March 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29442998/acute-kidney-injury-following-percutaneous-edge-to-edge-vs-minimally-invasive-surgical-mitral-valve-repair-incidence-predictors-and-prognostic-value
#7
Maria Isabel Körber, Maximilian Scherner, Kathrin Kuhr, Hugai Kasisada, Svenja Ney, Roman Pfister, Parwis Rahmanian, Jens Wippermann, Thorsten Wahlers, Stephan Baldus, Volker Rudolph
AIMS: This study sought to determine the incidence and identify predictors of acute kidney injury (AKI) following percutaneous edge-to-edge mitral valve repair (PMVR) and compare the risk of AKI between PMVR and surgical mitral valve repair (SMVR). METHODS AND RESULTS: We performed a single-centre analysis of 378 patients receiving treatment for mitral regurgitation (196 consecutive patients undergoing PMVR and 182 patients undergoing SMVR). The incidence of AKI (any stage according to KDIGO) following PMVR was 17...
October 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29427773/tissue-engineered-vascular-grafts-in-children-with-congenital-heart-disease-intermediate-term-followup
#8
Tadahisa Sugiura, Goki Matsumura, Shinka Miyamoto, Hideki Miyachi, Christopher K Breuer, Toshiharu Shinoka
OBJECTIVE: Tissue engineering holds great promise for the advancement of cardiovascular surgery as well as other medical fields. Tissue-engineered vascular grafts have the ability to grow and remodel and could therefore make great advances for pediatric cardiovascular surgery. In 2001, we began a human clinical trial evaluating these grafts in patients with a univentricular physiology. Herein, we report the long-term results of patients who underwent implantation of tissue-engineered vascular grafts as extracardiac total cavopulmonary conduits...
February 7, 2018: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29426746/image-guided-adaptive-brachytherapy-in-primary-vaginal-cancers-a-monocentric-experience
#9
Andres Huertas, Isabelle Dumas, Alexandre Escande, Eleonor Rivin Del Campo, Tony Felefly, Charles-Henri Canova, Anne Tailleur, Sebastien Gouy, Enrica Bentivegna, Philippe Morice, Christine Haie-Meder, Cyrus Chargari, Renaud Mazeron
PURPOSE: Primary vaginal cancer is a rare disease for which treatment has been modeled based on cervical cancer. We report our experience in the use of image-guided adaptive brachytherapy (IGABT) in this indication. METHODS AND MATERIALS: Patients treated for vaginal cancer with a combination of external beam radiation therapy and IGABT were identified through electronic search. The Groupe Européen de Curiethérapie-European Society for Radiotherapy and Oncology recommendations for cervical cancer have been extrapolated with the definition of two clinical target volumes (CTVs) corresponding to the residual disease after external beam radiation therapy (CTV BT ), assessed from clinical and imaging findings, and the so-called CTV i , comprising the CTV BT with directional margins and at least the initial disease at diagnosis...
February 6, 2018: Brachytherapy
https://www.readbyqxmd.com/read/29426745/single-institutional-outcomes-of-adjuvant-brachytherapy-for-stage-i-endometrial-cancer-are-outcomes-consistent-with-randomized-studies
#10
Michael J Dohopolski, Zachary D Horne, Brian J Gebhardt, Scott M Glaser, Robert P Edwards, Joseph L Kelley, John T Comerci, Alexander B Olawaiye, Madeleine Courtney-Brooks, Jessica L Berger, Paniti Sukumvanich, Sushil Beriwal
PURPOSE: Vaginal brachytherapy (VBT) alone has been shown to be a viable adjuvant treatment strategy for most patients with Stage I endometrioid endometrial cancer. We sought to examine our institutional data following practice pattern changes resulting from the publications of GOG-99 and PORTEC-2. METHODS AND MATERIALS: We retrospectively analyzed women who underwent adjuvant VBT after surgical staging for Stage 1 endometrioid endometrial cancer at our institution from 2007 to 2014...
February 6, 2018: Brachytherapy
https://www.readbyqxmd.com/read/29425323/long-term-effectiveness-of-gross-total-resection-for-symptomatic-spinal-cord-cavernous-malformations
#11
Tej D Azad, Anand Veeravagu, Amy Li, Michael Zhang, Venkatesh Madhugiri, Gary K Steinberg
BACKGROUND: Intramedullary spinal cord cavernous malformations (CMs) account for 5% of all CMs in the central nervous system and 5% to 12% of all spinal cord vascular lesions, yet their optimal management is controversial. OBJECTIVE: To identify factors associated with the clinical progression of spinal cord CMs and quantify the range of surgical outcomes. METHODS: Retrospective observational cohort study of 32 patients who underwent open surgical resection for spinal CMs, the majority of which presented to a dorsal or lateral pial surface, from 1996 to 2017 at a single institution...
February 6, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29419465/safety-and-humoral-and-cell-mediated-immune-responses-to-herpes-zoster-vaccine-in-patients-with-rheumatoid-arthritis
#12
Jung Hee Koh, Jaeseon Lee, Seo Hwa Kim, Seung-Ki Kwok, Ji Hyeon Ju, Sung-Hwan Park
OBJECTIVE: To examine humoral and cellular immune responses induced by a live attenuated herpes zoster (HZ) vaccine in patients with rheumatoid arthritis (RA) compared with osteoarthritis (OA) patients. METHODS: This was an observational study of a live attenuated HZ vaccine in 41 patients with RA receiving conventional disease-modifying antirheumatic drugs (cDMARD) and/or low-dose glucocorticoids (GC) and in 28 patients with OA. Blood samples were obtained before and at 12 weeks after HZ vaccination...
February 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29419329/understanding-gastroschisis-and-its-clinical-management-where-are-we
#13
Candace Haddock, Erik D Skarsgard
Gastroschisis is the commonest developmental defect of the anterior abdominal wall in both developed and developing countries. The past 30 years have seen transformational improvements in outcome due to advances in neonatal intensive care and enhanced integration between the disciplines of maternal fetal medicine, neonatology and pediatric surgery. A review of gastroschisis, which emphasizes its epidemiology, multidisciplinary care strategies and contemporary outcomes is timely. Areas covered: This review discusses the current state of knowledge related to prevalence and causation, and postulated embryopathologic mechanisms contributing to the development of gastroschisis...
February 8, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29416175/could-routine-magnetic-resonance-imaging-detect-local-recurrence-of-musculoskeletal-sarcomas-earlier-a-cost-effectiveness-study
#14
Andrew George, Robert J Grimer, Steven L J James
Background: Current practice in our unit is to perform clinical assessment and plain film radiographs at regular intervals following treatment of a bone or soft tissue sarcoma (STS). Cross-sectional imaging is used in cases with a clinical suspicion of recurrence. We aimed to investigate the effectiveness of this protocol to determine if earlier detection may have been possible had more intensive imaging been undertaken, and whether this may have affected outcome. Materials and Methods: We reviewed clinical records and imaging of all patients with diagnosed local recurrence (LR) in the previous 5 years to investigate: how it was diagnosed, the site and size of recurrence, and management...
January 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29416173/does-radiotherapy-after-surgery-affect-outcomes-in-ewing-s-sarcoma-of-the-pelvis
#15
Ajay Puri, Ashish Gulia, Saniya Crasto, Tushar Vora, Nehal Khanna, Siddharth Laskar
Background: The impact of postoperative radiotherapy (PORT) on outcomes has been a matter of debate after adequate resection in Ewing's sarcoma of the pelvis. We evaluated our cases after surgical excision in pelvic Ewing's sarcoma and assessed local control and overall survival (OS) with respect to PORT and chemotherapy-induced percentage necrosis. Materials and Methods: Forty four surgically operated patients (June 2002-November 2014) of localized Ewing's sarcoma were retrospectively reviewed...
January 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29416164/retrospective-analysis-of-giant-cell-tumor-lower-end-radius-treated-with-en-bloc-excision-and-translocation-of-ulna
#16
Amit Vyas, Purnima Patni, Narender Saini, Rahul Sharma, Vinit Arora, S P Gupta
Background: Distal end of radius is third most common site for GCT of long bones and 1% of these metastasize mostly to lungs. Reconstruction methods commonly used are fibula (vascularized and nonvascularized), centralization of ulna, translocation of ulna, and endoprosthetic replacement. We report the outcome of series of twenty cases where we did en bloc excision of tumor with translocation of ulna. Materials and Methods: Twenty cases of giant cell tumor (GCT) of lower end of radius were included in this retrospective study...
January 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29416163/fibulectomy-for-primary-proximal-fibular-bone-tumors-a-functional-and-clinical-outcome-in-46-patients
#17
Zile Singh Kundu, Milind Tanwar, Parveen Rana, Rajeev Sen
Background: Primary benign and malignant tumors of the proximal fibula are not very common. Upper fibula being an expendable bone; the majority of the primary bone tumors at this site are usually treated with en bloc proximal fibulectomy. There is scarce literature on functional results, difficulties faced during dissection when to preserve or sacrifice common peroneal nerve and importance of lateral collateral ligament repair after proximal fibulectomy. The present study attempts at assessing these variables...
January 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29409294/is-generalized-ligamentous-laxity-a-prognostic-factor-for-recurred-hallux-valgus-deformity
#18
Byung-Ki Cho, Ji-Kang Park, Seung-Myung Choi, Nelson F SooHoo
BACKGROUND: This study was performed to evaluate the intermediate-term clinical outcomes after proximal chevron osteotomy for hallux valgus in patients with generalized ligamentous laxity, and to determine the effect on postoperative recurrence of deformity. METHODS: There were 23 cases in laxity group (Beighton score ≥5 points) and 175 in non-laxity group with a mean followup of 46.3 months. Clinical evaluation consisted of the AOFAS score, Foot and Ankle Ability Measure (FAAM), and radiographic measurement of hallux alignment...
October 13, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409265/use-of-intramedullary-carbon-fiber-nail-in-hindfoot-fusion-a-small-cohort-study
#19
Ibukunoluwa B Araoye, Yvonne E Chodaba, Kenneth S Smith, Ryan W Hadden, Ashish B Shah
BACKGROUND: Current literature on carbon fiber implant use in foot and ankle surgery is scant. The purpose of this paper is to report medium-term outcomes of hindfoot fusion using a carbon fiber intramedullary nail. METHODS: We retrospectively reviewed 30 cases of hindfoot fusion using carbon fiber intramedullary nail fixation between 2014 and 2017. We excluded revisions and cases with bulk allograft or ankle infection prior to surgery. We reviewed charts for length of followup, radiographic union, and complications...
July 29, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29408833/many-shoulder-mri-findings-in-elite-professional-throwing-athletes-resolve-after-retirement-a-clinical-and-radiographic-study
#20
Michael O Schär, Simone Dellenbach, Christian W Pfirrmann, Sumit Raniga, Bernhard Jost, Matthias A Zumstein
BACKGROUND: Anatomic findings on MRI scans of the shoulder likely affect patients differently based on their physical demands and fitness levels. The natural history of these anatomic findings once professional overhead athletes retire remains unclear. A better understanding of what happens with these findings after retirement may influence how we manage shoulder problems in athletes. PURPOSE: (1) What is the natural history of MRI-observed findings in the throwing and nonthrowing shoulders of professional European handball players after retirement from the sport? What proportion of these individuals have diagnosable findings on MRI, and do these findings disappear after retirement? (2) Do clinical findings such as Constant and Murley score and shoulder ROM change after retirement in these professional overhead athletes? METHODS: The inception cohort of this series consisted of the entire Swiss National European handball team except the goalkeepers...
March 2018: Clinical Orthopaedics and related Research
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