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https://www.readbyqxmd.com/read/28811353/the-omeract-rheumatoid-arthritis-magnetic-resonance-imaging-mri-scoring-system-updated-recommendations-by-the-omeract-mri-in-arthritis-working-group
#1
Mikkel Østergaard, Charles G Peterfy, Paul Bird, Frédérique Gandjbakhch, Daniel Glinatsi, Iris Eshed, Espen A Haavardsholm, Siri Lillegraven, Pernille Bøyesen, Bo Ejbjerg, Violaine Foltz, Paul Emery, Harry K Genant, Philip G Conaghan
OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) Rheumatoid Arthritis (RA) Magnetic Resonance Imaging (MRI) scoring system (RAMRIS), evaluating bone erosion, bone marrow edema/osteitis, and synovitis, was introduced in 2002, and is now the standard method of objectively quantifying inflammation and damage by MRI in RA trials. The objective of this paper was to identify subsequent advances and based on them, to provide updated recommendations for the RAMRIS. METHODS: MRI studies relevant for RAMRIS and technical and scientific advances were analyzed by the OMERACT MRI in Arthritis Working Group, which used these data to provide updated considerations on image acquisition, RAMRIS definitions, and scoring systems for the original and new RA pathologies...
August 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28807749/high-dose-rate-interstitial-brachytherapy-boost-in-inoperable-locally-advanced-tongue-carcinoma
#2
Miguel Angel Santos, Jose Luis Guinot, Maria Isabel Tortajada, Paula Santamaría, Valentin Campo, Laura Oliver, Marina Peña, Leoncio Arribas
PURPOSE: Locally advanced tongue carcinomas (LATCs) in inoperable lesions are managed with external beam radiation therapy (EBRT) and chemotherapy. In our institution, the boost to the gross tumor volume is delivered with high-dose-rate brachytherapy (HDR-BT) after EBRT. We review the outcome of these patients when HDR-BT is added as a boost. METHODS AND MATERIALS: From May 2000 to December 2014, a total of 24 patients with LATC, nonsurgical oral tongue, and base of tongue carcinomas were treated with EBRT and with interstitial plastic tubes for brachytherapy; median dose was 18-24 Gy in 6-8 fractions after 50-60 Gy of EBRT...
August 11, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28807748/dosimetric-analysis-and-preliminary-clinical-result-of-image-guided-brachytherapy-with-or-without-hybrid-technique-for-cervical-cancer-using-varisource-titanium-ring-applicator-with-siriraj-ring-cap
#3
Pittaya Dankulchai, Suphalerk Lohasammakul, Janjira Petsuksiri, Pitchayut Nakkrasae, Lalida Tuntipumiamorn, Chumpot Kakanaporn, Yaowalak Chansilpa
PURPOSE: Titanium ring cap applicator (VariSource) was applied in treating cervical cancer patients by using image-guided brachytherapy (IGBT). However, its sizes appeared to be relatively large for most of our patients. Thus, we have developed a specific applicator "Siriraj Ring Cap," which is slightly smaller and more suitable for our patients. This study was to evaluate effectiveness of this equipment. METHODS AND MATERIALS: Locally advanced cervical cancer patients were treated with external beam radiation therapy with or without concomitant chemotherapy...
August 11, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28807747/pretreatment-3t-multiparametric-mri-staging-predicts-for-biochemical-failure-in-high-risk-prostate-cancer-treated-with-combination-high-dose-rate-brachytherapy-and-external-beam-radiotherapy
#4
John V Hegde, D Jeffrey Demanes, Darlene Veruttipong, Jagdeep Raince, Sang-June Park, Steven S Raman, Nicholas G Nickols, Christopher R King, Amar U Kishan, Michael L Steinberg, Mitchell Kamrava
PURPOSE: To determine whether pretreatment 3T multiparametric MRI (mpMRI) staging impacts biochemical recurrence-free survival (BRFS) or distant metastasis-free survival (DMFS) for men with high-risk prostate cancer treated with combination high-dose-rate (HDR) brachytherapy and external beam radiation therapy (EBRT). MATERIALS AND METHODS: This institutional review board-approved retrospective study included a cohort of 37 men with high-risk prostate cancer treated with HDR brachytherapy and EBRT after 3T mpMRI...
August 11, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28804988/patterns-of-systemic-treatment-for-psoriatic-arthritis-in-the-united-states-2004-2015
#5
Moa P Lee, Joyce Lii, Yinzhu Jin, Rishi J Desai, Daniel H Solomon, Joseph F Merola, Seoyoung C Kim
OBJECTIVE: To examine trends in use of systemic disease-modifying antirheumatic drugs (DMARD) among patients with psoriatic arthritis (PsA) in the U.S. METHODS: Using claims data (2004-2015) from a large U.S. commercial healthplan, we identified patients with PsA who initiated DMARDs. We examined baseline patient characteristics and initial treatment patterns. We then assessed changes in the DMARD regimen over the 12-month period after the 1(st) DMARD initiation date...
August 13, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28801877/are-barbed-sutures-associated-with-90-day-reoperation-rates-after-primary-tka
#6
Daniel C Austin, Benjamin J Keeney, Brendan E Dempsey, Karl M Koenig
BACKGROUND: Studies have suggested that barbed sutures for wound closure in TKAs are an acceptable alternative to standard methods. However others have observed a higher risk of wound-related complications with barbed sutures. QUESTIONS/PURPOSES: (1) Do 90-day TKA reoperation rates differ between patients undergoing a barbed suture arthrotomy closure compared with a traditional interrupted closure? (2) Do the 90-day reoperation rates of wound-related, deep infection, and arthrotomy failure complications differ between barbed suture and traditional closures? METHODS: A retrospective analysis of a longitudinally maintained institutional primary TKA database was conducted on all TKAs performed between April 2011 and September 2015...
August 11, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28801116/comparative-results-of-three-short-brachytherapy-schedules-as-exclusive-treatment-in-postoperative-endometrial-carcinoma
#7
Ángeles Rovirosa, Antonio Herreros, Cristina Camacho, Carlos Ascaso, Joan Sánchez, Stepphania Cortés, Sebastià Sabater, Jordi Solà, Aureli Torné, Meritxell Arenas
PURPOSE: To compare vaginal control and treatment toxicity of three different high-dose-rate brachytherapy schedules as exclusive treatment in postoperative endometrial carcinoma. METHODS AND MATERIALS: From 2003 to 2015, three different schedules were used as postoperative treatment for 146 patients (p) with intermediate-risk endometrial carcinoma. Group 1 (41 p): six fractions of 4-6 Gy, 3-4 fractions per week; Group 2 (59 p): four fractions of 5-6 Gy administered daily; Group 3 (46 p): 6 Gy × 3 fractions in three consecutive days...
August 8, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28798831/an-in-house-composix%C3%A2-based-pubovaginal-sling-trial-for-female-stress-urinary-incontinence-five-year-comparative-followup-to-tension-free-and-transobturator-vaginal-tapes
#8
Tal Ben-Zvi, Katherine Moore, Nadim Haidar, Mireille Gregoire
INTRODUCTION: We compared the efficacy of three slings in the long-term treatment of stress urinary incontinence (SUI): tension-free vaginal tape (TVT), vaginal tape-obturator (TVT-O), and an in-house two-layered polypropylene mesh with a submicronic polytetrafluoroethylene (Composix™). Our primary endpoint was the objective measurement of continence (24-hour pad test). Secondarily, we measured the satisfaction and complication rates. METHODS: This prospective, non-randomized study included 128 patients with SUI...
August 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28798825/ex-vivo-ureteroscopy-of-deceased-donor-kidneys
#9
Graham L Machen, Preston A Milburn, Patrick S Lowry, Jacqueline A Lappin, Debra K Doherty, Marawan M El Tayeb
INTRODUCTION: When encountered, the ideal management of lithiasis in deceased donor kidneys is not well-defined. With advances in endourological techniques, minimally invasive treatments are becoming an increasingly viable option. We set out to describe our experience performing ex-vivo ureteroscopy on cadaveric donor kidneys, including one in which the procedure was completed on-pump. METHODS: A retrospective chart review was undertaken to identify patients who had undergone ex-vivo ureteroscopy prior to cadaveric renal transplant...
August 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28791443/outcomes-of-shoulder-arthroplasty-in-haematopoietic-stem-cell-transplant-patients
#10
Joseph M Statz, Brian P Chalmers, Cameron K Ledford, Joaquin Sanchez-Sotelo, John W Sperling, Mark E Morrey
BACKGROUND: With the growing population of patients undergoing haematopoietic stem cell transplants (HSCTs), the demand for shoulder arthroplasty (SA) in this population can be expected to increase. No studies in the literature have examined the outcomes of SA in HSCT patients. PATIENTS AND METHODS: A retrospective review of 11 SAs in 10 patients with previous HSCT was performed. We characterized the clinical outcomes, survivorship, and peri-operative complication rates in patients who underwent SA after receiving a HSCT...
August 9, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28790476/surgical-treatment-of-sanders-type-2-calcaneal-fractures-using-a-sinus-tarsi-approach
#11
Chul Hyun Park, Dong Yeol Lee
BACKGROUND: Calcaneum is the most commonly fractured tarsal bone. The optimal treatment for displaced calcaneus fractures involving the posterior facet is surgical. The extensile lateral approach is commonly preferred because it provides sufficient exposure of the subtalar facet. However, this technique has the risk of complications such as wound necrosis and sural nerve injury. Various minimally invasive approaches, such as sinus tarsi approach, limited posterior approach, and percutaneous approach, have been introduced to reduce possible complications...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28790473/longitudinal-followup-of-incidentally-detected-pseudotumors-in-patients-with-metal-on-metal-implants-a-retrospective-study
#12
Khushboo Pilania, Bhavin Jankharia
BACKGROUND: This study describes the significance and temporal evolution of incidentally detected, presumed, metal-induced reactive periprosthetic masses in patients with metal on metal (MoM) hip arthroplasty and its management. The literature concerning the temporal evolution of these lesions is meagre and so it is still unclear, whether asymptomatic patients with periprosthetic collections should undergo revision. MATERIALS AND METHODS: Patients with MoM hip replacements fitted with a recalled implant (ASR, DuPuy) often undergo magnetic resonance imaging with metal artifact reduction sequences to look for complications...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28790472/total-hip-arthroplasty-in-patients-of-post-polio-residual-paralysis-a-retrospective-case-series
#13
Francisco Borja Sobrón, Álvaro Martínez-Ayora, Manuel Cuervas-Mons, Tania Quevedo, Rafael Laguna, Javier Vaquero
BACKGROUND: Poliomyelitis is a viral, nervous system disease that affects both the upper and the lower extremities. The treatment of severe coxarthrosis in these patients with total hip arthroplasty (THA) has been widely questioned because of the high risk of subsequent complications. The aim of the present study was to describe both radiological and medium term clinical results in a series of patients with post polio residual paralysis that underwent THA. MATERIALS AND METHODS: We report a retrospective review of a series of 5 five patients diagnosed with severe coxarthrosis secondary to post polio residual paralysis who were operated between 2008 and 2012...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28790470/management-guidelines-for-metal-on-metal-hip-resurfacing-arthroplasty-a-strategy-on-followup
#14
Naoki Nakano, Andrea Volpin, Jonathan Bartlett, Vikas Khanduja
Despite the initial promise of metal-on-metal (MoM) implants as the ideal bearing surface for hip replacements and resurfacings, high short term failure rates due to an adverse reaction to metal debris (ARMD) have led to a dramatic reduction in the number of MoM implants used in the modern era. With over one million patients worldwide having undergone hip operations utilizing a MoM bearing surface, the long term outcomes for such patients remains unknown, and there is much debate as to the most effective management of these patients...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28789635/simultaneous-antegrade-and-retrograde-endoscopic-treatment-of-non-malignant-ureterointestinal-anastomotic-strictures-following-urinary-diversion
#15
Weiguo Hu, Boxing Su, Bo Xiao, Xin Zhang, Song Chen, Yuzhe Tang, Yubao Liu, Meng Fu, Jianxing Li
BACKGROUND: The ureterointestinal anastomosis stricture (UAS) is a common complication of urinary diversion after radical cystectomy. For decades, open anastomotic revision remained the gold standard for the treatment of UAS. However, with the advancement in endoscopic technology, mini-invasive therapeutic approaches have been used in its management. Here, we report our experience with and long-term results of combined simultaneous antegrade and retrograde endoscopy (SARE) in the treatment of non-malignant UASs after urinary diversion in a consecutive series of patients...
August 8, 2017: BMC Urology
https://www.readbyqxmd.com/read/28765257/tenosynovial-giant-cell-tumor-incidence-prevalence-patient-characteristics-and-recurrence-a-registry-based-cohort-study-in-denmark
#16
Vera Ehrenstein, Søren L Andersen, Ibrahim Qazi, Neil Sankar, Alma B Pedersen, Robert Sikorski, John F Acquavella
OBJECTIVE: Tenosynovial giant cell tumor (TGCT) is a rare benign proliferative and inflammatory disease arising from synovia of joints, bursae, or tendon sheaths. We aimed to estimate incidence rate and prevalence of TGCT in Denmark, to describe patient characteristics and treatment modalities among patients with TGCT, and to estimate risk of TGCT recurrence. METHODS: Using registry data on pathology examinations and inpatient and outpatient hospital diagnoses, we identified adult patients with diagnoses of diffuse TGCT (D-TGCT) or localized TGCT (L-TGCT) between 1997 and 2012, followed through 2012...
August 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28765255/malignancy-in-pediatric-onset-systemic-lupus-erythematosus
#17
Sasha Bernatsky, Ann E Clarke, Omid Zahedi Niaki, Jeremy Labrecque, Laura E Schanberg, Earl D Silverman, Kristen Hayward, Lisa Imundo, Hermine I Brunner, Kathleen A Haines, Randy Q Cron, Kiem Oen, Linda Wagner-Weiner, Alan M Rosenberg, Kathleen M O'Neil, Ciarán M Duffy, Emily von Scheven, Lawrence Joseph, Jennifer L Lee, Rosalind Ramsey-Goldman
OBJECTIVE: To determine cancer incidence in a large pediatric-onset systemic lupus erythematosus (SLE) population. METHODS: Data were examined from 12 pediatric SLE registries in North America. Patients were linked to their regional cancer registries to detect cancers observed after cohort entry, defined as date first seen in the clinic. The expected number of malignancies was obtained by multiplying the person-years in the cohort (defined from cohort entry to end of followup) by the geographically matched age-, sex-, and calendar year-specific cancer rates...
August 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28765251/severe-infection-in-antineutrophil-cytoplasmic-antibody-associated-vasculitis
#18
Aladdin J Mohammad, Mårten Segelmark, Rona Smith, Martin Englund, Jan-Åke Nilsson, Kerstin Westman, Peter A Merkel, David R W Jayne
OBJECTIVE: To compare the rate of severe infections after the onset of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with the rate in the background population, and to identify predictors of severe infections among patients with AAV. METHODS: The study cohort was 186 patients with AAV diagnosed from 1998 to 2010, consisting of all known cases in a defined population in southern Sweden. For each patient, 4 age- and sex-matched reference subjects were randomly chosen from the background population...
August 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28765247/a-longitudinal-study-of-ambulatory-physician-encounters-emergency-room-visits-and-hospitalizations-by-patients-with-rheumatoid-arthritis-a-13-year-population-health-study
#19
John G Hanly, Kara Thompson, Chris Skedgel
OBJECTIVE: To determine total physician encounters, emergency room (ER) visits, and hospitalizations in an incident cohort of rheumatoid arthritis (RA) cases and matched control patients over 13 years. METHODS: A retrospective cohort study was performed using administrative healthcare data from about 1 million people with access to universal healthcare. Using the International Classification of Diseases, 9th ed (ICD-9) and ICD-10 diagnostic codes, 7 RA case definitions were used...
August 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28765243/corticosteroid-or-nonsteroidal-antiinflammatory-drugs-for-the-treatment-of-acute-gout-a-systematic-review-of-randomized-controlled-trials
#20
Christy Amanda Billy, Ricky Tanujaya Lim, Marinella Ruospo, Suetonia C Palmer, Giovanni F M Strippoli
OBJECTIVE: Nonsteroidal antiinflammatory drugs (NSAID) are used as first-line agents to treat acute gout. Recent trials suggest a possible first-line role for corticosteroids. METHODS: We conducted a metaanalysis of randomized controlled trials (RCT) evaluating corticosteroid versus NSAID therapy (nonselective and selective) as treatment for acute gout. MEDLINE, EMBASE, and CENTRAL were systematically searched through August 2016. Outcomes included pain, bleeding, joint swelling, erythema, tenderness, activity limitation, response to therapy, quality of life, time to resolution, supplementary analgesics, and adverse events...
August 1, 2017: Journal of Rheumatology
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