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https://www.readbyqxmd.com/read/27898185/perfusion-has-no-effect-on-the-in-vivo-cest-effect-from-cr-crcest-in-skeletal-muscle
#1
Feliks Kogan, Randall B Stafford, Erin K Englund, Garry E Gold, Hari Hariharan, John A Detre, Ravinder Reddy
Creatine, a key component of muscle energy metabolism, exhibits a chemical exchange saturation transfer (CEST) effect between its amine group and bulk water, which has been exploited to spatially and temporally map creatine changes in skeletal muscle before and after exercise. In addition, exercise leads to an increase in muscle perfusion. In this work, we determined the effects of perfused blood on the CEST effects from creatine in skeletal muscle. Experiments were performed on healthy human subjects (n = 5) on a whole-body Siemens 7T magnetic resonance imaging (MRI) scanner with a 28-channel radiofrequency (RF) coil...
November 29, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27890833/pulse-wave-analysis-after-treatment-of-abdominal-aortic-aneurysms-with-the-ovation-device
#2
Efstratios Georgakarakos, Christos Argyriou, George S Georgiadis, Miltos K Lazarides
BACKGROUND: Ovation Aortic Stent-Graft System is a new device for the endovascular treatment of Abdominal Aortic Aneurysms achieving fixation via a 35-mm long, rigid ancored suprarenal stent and sealing stent at the infrarenal level by a means of a polymer-filling pair of inflatable O-rings which cause narrowing of flow lumen and regional stenosis. Thus, concerns have been raised regarding hemodynamic consequences associated with this new desing . Our preliminary report showed no significant increase of aortic pulse wave velocity (aPWV) immediately after implantation of the Ovation in 3 patients...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27878503/evaluation-of-different-near-infrared-spectroscopy-technologies-for-assessment-of-tissue-oxygen-saturation-during-a-vascular-occlusion-test
#3
Kevin Steenhaut, Koen Lapage, Thierry Bové, Stefan De Hert, Annelies Moerman
An increasing number of NIRS devices are used to provide measurements of peripheral tissue oxygen saturation (StO2). The aim of the present study is to test the hypothesis that despite technological differences between devices, similar trend values will be obtained during a vascular occlusion test. The devices compared are NIRO-200NX, which measures StO2 and oxyhemoglobin by spatially resolved spectroscopy and the Beer-Lambert law, respectively, and INVOS 5100C and Foresight Elite, which both measure StO2 with the Beer-Lambert law, enhanced with the spatial resolution technique...
November 22, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27833679/endotracheal-tube-cuff-pressures-in-patients-intubated-prior-to-helicopter-ems-transport
#4
Joseph Tennyson, Tucker Ford-Webb, Stacy Weisberg, Donald LeBlanc
INTRODUCTION: Endotracheal intubation is a common intervention in critical care patients undergoing helicopter emergency medical services (HEMS) transportation. Measurement of endotracheal tube (ETT) cuff pressures is not common practice in patients referred to our service. Animal studies have demonstrated an association between the pressure of the ETT cuff on the tracheal mucosa and decreased blood flow leading to mucosal ischemia and scarring. Cuff pressures greater than 30 cmH2O impede mucosal capillary blood flow...
November 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27833487/measurement-of-endotracheal-tube-cuff-pressure-instrumental-versus-conventional-method
#5
Mueen Ullah Khan, Rashid Khokar, Sadia Qureshi, Tariq Al Zahrani, Mansoor Aqil, Motasim Shiraz
OBJECTIVE: To evaluate the conventional practice of endotracheal tube (ETT) cuff inflation and pressure measurement as compared to the instrumental method. STUDY DESIGN: Prospective observational study. PLACE AND DURATION OF STUDY: Department of Anaesthesia, King Saud University Hospital, Riyadh, Saudi Arabia (June 2014-July 2014). METHODS: A total of 100 adult patients were observed according to the syringe size used Group-1 (10 ml) and Group-2 (20 ml) for ETT cuff inflation in general anesthesia...
October 2016: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/27824690/hypertension-during-weight-lifting-reduces-flow-mediated-dilation-in-nonathletes
#6
Cullen E Buchanan, Andrew O Kadlec, Anne Z Hoch, David D Gutterman, Matthew J Durand
PURPOSE: The purpose of this study was to determine if increased intraluminal pressure is the damaging factor which reduces flow mediated dilation (FMD) in young, healthy subjects following resistance exercise to maximal exertion. HYPOTHESIS: Attenuating the rise in brachial artery pressure during weight lifting by placing a blood pressure cuff on the upper arm prevents post-exercise impairment of brachial artery FMD in sedentary individuals. METHODS: Nine sedentary individuals who exercise ≤1 time/week and six exercise-trained individuals who exercise ≥3 times/week performed leg press exercise to maximal exertion on two separate occasions...
November 7, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27807663/effect-of-posture-and-extracranial-contamination-on-results-of-cerebral-oximetry-by-near-infrared-spectroscopy
#7
Shinya Kato, Kenji Yoshitani, Yosuke Kubota, Yuzuru Inatomi, Yoshihiko Ohnishi
BACKGROUND: Near-infrared spectroscopy (NIRS)-based cerebral oximetry is a noninvasive technology used to estimate regional cerebral oxygen saturation (rSO2). Extracranial blood flow is known to substantially affect rSO2 values measured by most clinically available devices. Several studies have also reported that the Trendelenburg position and upright position have a larger effect on rSO2 measurements than the supine position. Therefore, we investigated the effect of these two positions (the Trendelenburg position versus the upright position) and extracranial contamination on rSO2 measurements obtained using two commercially available devices and one prototype device...
November 2, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27782305/pulse-oximeter-derived-blood-pressure-measurement-in-patients-with-a-continuous-flow-left-ventricular-assist-device
#8
Yaron Hellman, Adnan S Malik, Kathleen A Lane, Changyu Shen, I-Wen Wang, Thomas C Wozniak, Zubair A Hashmi, Sarah D Munson, Jeanette Pickrell, Marco A Caccamo, Irmina Gradus-Pizlo, Azam Hadi
Currently, blood pressure (BP) measurement is obtained noninvasively in patients with continuous flow left ventricular assist device (LVAD) by placing a Doppler probe over the brachial or radial artery with inflation and deflation of a manual BP cuff. We hypothesized that replacing the Doppler probe with a finger-based pulse oximeter can yield BP measurements similar to the Doppler derived mean arterial pressure (MAP). We conducted a prospective study consisting of patients with contemporary continuous flow LVADs...
October 26, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27761035/a-randomised-trial-to-compare-i-gel-and-proseal%C3%A2-laryngeal-mask-airway-for-airway-management-in-paediatric-patients
#9
R Nirupa, Satinder Gombar, Vanita Ahuja, Preeti Sharma
BACKGROUND AND AIMS: i-gel™ is a newer supraglottic airway device with a unique non-inflatable cuff. We aimed to compare i-gel™ with ProSeal™ laryngeal mask airway (PLMA™) in children scheduled for surgery under general anaesthesia (GA) with controlled ventilation. METHODS: This prospective, randomised controlled study was conducted in 100 surgical patients, aged 2-6 years of American Society of Anesthesiologists Physical Status I-II scheduled under GA. Patients were randomly allocated to receive either size 2 i-gel™ or PLMA™ as an airway device...
October 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27754264/os-37-07-could-flow-mediated-slowing-constitute-a-methodological-alternative-to-the-conventional-echo-tracking-flow-mediated-dilation-technique-for-the-evaluation-of-endothelial-function-preliminary-results
#10
Telmo Pereira, Armindo Almeida, João Maldonado, Jorge Conde
OBJECTIVE: The Moens-Korteweg equation predicts changes in pulse wave velocity (PWV) following changes in arterial radius, therefore an increase in arterial radius, as seen in a reactive hyperaemia (RH) condition, should slow PWV over a given arterial segment. If this assumption is true, than the deceleration of PWV over the brachial artery (flow-mediated slowing - FMS) should be an equivalent signal of endothelial function during a conventional RH flow-mediated dilation (FMD) procedure...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754015/br-04-1management-of-treatment-resistant-hypertension
#11
David John Webb
Treatment-resistant hypertension (TRH) is defined as the failure to achieve an office BP target of <140/90 mmHg (<130/80 mmHg in patients with chronic kidney disease (CKD) or diabetes) in patients with hypertension (HT), despite adherence to at least 3 antihypertensive medications at optimal tolerated doses, ideally including a diuretic (Calhoun et al., Circulation 2008). TRH identifies patients with hard-to-treat HT, who might benefit from specialist investigation and treatment. Although some studies put the prevalence of TRH as >10%, these levels may be inflated by white-coat hypertension and poor adherence...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753849/ed-03-4-high-tech-in-blood-pressure-monitoring-where-are-we-going
#12
Seung Woo Park
Rapid progress of mobile information technologies such as wearable sensors, wireless communication, and world-wide use of smartphone cause digital health innovations. In the field of hypertension, wearable blood pressure (BP) monitoring and its wireless transfer to anywhere through smartphone, mobile smartphone apps, and cuffless blood pressure monitoring system are expected to change the way of diagnosis and management of hypertension. Home BP monitoring would be easier and wireless data transfer to health care providers would be common...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27746545/comparison-of-i-gel%C3%A2-and-laryngeal-mask-airway-classic%C3%A2-in-terms-of-ease-of-insertion-and-hemodynamic-response-a-randomized-observational-study
#13
N Pratheeba, G S Ramya, R V Ranjan, R Remadevi
CONTEXT: Laryngeal mask airway (LMA) Classic™ has an inflatable cuff while i-gel™ has a noninflatable cuff made of thermoplastic elastomer. AIMS: To compare ease of insertion, number, and duration of insertion attempts among the two device. Secondary objectives were to evaluate the hemodynamic response and SpO2 during device insertion and during maintenance of general anesthesia. SETTINGS AND DESIGN: This study was conducted as randomized observational study in a teaching hospital...
September 2016: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/27722109/effect-of-tracheostomy-tube-on-work-of-breathing-comparison-of-pre-and-post-decannulation
#14
Darío Villalba, Viviana Feld, Valeria Leiva, Mariana Scrigna, Eduardo Distéfano, Romina Pratto, Matías Rodriguez, Jesica Collins, Ana Rocco, Amelia Matesa, Damián Rossi, Laura Areas, Sacha Virgilio, Nicolás Golfarini, Gregorio Gil-Rosetti, Pablo Diaz-Ballve, Fernando Planells
OBJECTIVE: To describe and compare the work of breathing (WOB) during spontaneous breathing under four conditions: (1) breathing through a tracheostomy tube with an inflated cuff, (2) breathing through the upper airway (UA) with a deflated cuff and occluded tube, (3) breathing through the UA with an occluded cuffless tube, and (4) postdecannulation. PATIENTS AND METHODS: Patients who tolerated an occluded cuffless tube were included. Ventilatory variables and esophageal pressure were recorded...
July 2016: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/27717653/the-time-dependence-of-the-effect-of-ischemic-preconditioning-on-successive-sprint-swimming-performance
#15
Felipe D Lisbôa, Tiago Turnes, Rogério S O Cruz, João A G Raimundo, Gustavo S Pereira, Fabrizio Caputo
OBJECTIVES: The present study aimed to determine the effects of ischemic preconditioning on performance in three successive 50-m swimming trials and to measure stroke rate, stroke length and blood lactate accumulation. DESIGN: Counterbalanced, repeated-measures cross-over study. METHODS: On two separate days, eleven competitive male swimmers (20±3 years, 182±5cm, 77±5kg) performed three successive 50-m trials in a 50-m swimming pool, preceded by intermittent bilateral cuff inflation (4× 5-min of blood flow restriction+5-min of cuff deflation) at either 220 for thighs and 180mmHg for arms (ischemic preconditioning) or 20mmHg for both limbs (control-treatment)...
September 20, 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/27707723/acute-hot-water-immersion-is-protective-against-impaired-vascular-function-following-forearm-ischemia-reperfusion-in-young-healthy-humans
#16
Vienna E Brunt, Andrew T Jeckell, Brett R Ely, Matthew J Howard, Dick H J Thijssen, Christopher T Minson
Ischemia-reperfusion (I/R) injury is a primary cause of poor outcomes following ischemic cardiovascular events. We tested whether acute hot water immersion protects against forearm vascular I/R. Ten (5 male, 5 female) young (23 ± 2 yr), healthy subjects participated in two trials in random order 7-21 days apart, involving: 1) 60 min of seated rest (control), or 2) 60 min of immersion in 40.5°C water (peak rectal temperature: 38.9 ± 0.2°C). I/R was achieved 70 min following each intervention by inflating an upper arm cuff to 250 mmHg for 20 min followed by 20 min of reperfusion...
December 1, 2016: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/27643229/os-37-07-could-flow-mediated-slowing-constitute-a-methodological-alternative-to-the-conventional-echo-tracking-flow-mediated-dilation-technique-for-the-evaluation-of-endothelial-function-preliminary-results
#17
Telmo Pereira, Armindo Almeida, João Maldonado, Jorge Conde
OBJECTIVE: The Moens-Korteweg equation predicts changes in pulse wave velocity (PWV) following changes in arterial radius, therefore an increase in arterial radius, as seen in a reactive hyperaemia (RH) condition, should slow PWV over a given arterial segment. If this assumption is true, than the deceleration of PWV over the brachial artery (flow-mediated slowing - FMS) should be an equivalent signal of endothelial function during a conventional RH flow-mediated dilation (FMD) procedure...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643038/ed-03-4-high-tech-in-blood-pressure-monitoring-where-are-we-going
#18
Seung Woo Park
Rapid progress of mobile information technologies such as wearable sensors, wireless communication, and world-wide use of smartphone cause digital health innovations. In the field of hypertension, wearable blood pressure (BP) monitoring and its wireless transfer to anywhere through smartphone, mobile smartphone apps, and cuffless blood pressure monitoring system are expected to change the way of diagnosis and management of hypertension. Home BP monitoring would be easier and wireless data transfer to health care providers would be common...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642926/br-04-1management-of-treatment-resistant-hypertension
#19
David John Webb
Treatment-resistant hypertension (TRH) is defined as the failure to achieve an office BP target of <140/90 mmHg (<130/80 mmHg in patients with chronic kidney disease (CKD) or diabetes) in patients with hypertension (HT), despite adherence to at least 3 antihypertensive medications at optimal tolerated doses, ideally including a diuretic (Calhoun et al., Circulation 2008). TRH identifies patients with hard-to-treat HT, who might benefit from specialist investigation and treatment. Although some studies put the prevalence of TRH as >10%, these levels may be inflated by white-coat hypertension and poor adherence...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27608343/the-minimal-leak-test-technique-for-endotracheal-cuff-maintenance
#20
D A Harvie, J N Darvall, M Dodd, A De La Cruz, M Tacey, R L D'Costa, D Ward
Endotracheal tube (ETT) cuff pressure management is an essential part of airway management in intubated and mechanically ventilated patients. Both under- and over-inflation of the ETT cuff can lead to patient complications, with an ideal pressure range of 20-30 cmH2O defined. A range of techniques are employed to ensure adequate ETT cuff inflation, with little comparative data. We performed an observational cross-sectional study in a tertiary metropolitan ICU, assessing the relationship between the minimal leak test and cuff manometry...
September 2016: Anaesthesia and Intensive Care
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