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https://www.readbyqxmd.com/read/29471598/-ureteral-cancer-developing-in-retrocaval-ureter-a-case-report
#1
Yoshiaki Matsumura, Yusuke Iemura, Shinji Fukui, Yoriaki Kagebayashi, Shoji Samma, Shigehiro Tsujimoto, Takashi Okada, Toru Kanno
Ureteral cancer in the retrocaval ureter is rare. We herein report a patient with this condition laparoscopically treated. A 69-year-old man was referred to us because of right ureteral cancer diagnosed during ureteroscopic surgery for a ureteral calculus. Histological diagnosis of the ureteroscopically biopsied material was non-invasive papillary urothelial carcinoma, low grade (G2). Computed tomography (CT) demonstrated a retrocaval ureter : a double J stent placed during ureteroscopy assisted the diagnosis...
January 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29471590/consumer-use-and-response-to-online-third-party-raw-dna-interpretation-services
#2
Catharine Wang, Tiernan J Cahill, Andrew Parlato, Blake Wertz, Qiankun Zhong, Tricia Norkunas Cunningham, James J Cummings
BACKGROUND: With the availability of raw DNA generated from direct-to-consumer (DTC) testing companies, there has been a proliferation of third-party online services that are available to interpret the raw data for both genealogy and/or health purposes. This study examines the current landscape and downstream clinical implications of consumer use of third-party services. METHODS: Study participants were recruited online from social media platforms. A total of 321 survey respondents reported using third-party services for raw DNA interpretation...
January 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29471583/national-partnership-for-maternal-safety-consensus-bundle-on-safe-reduction-of-primary-cesarean-births-supporting-intended-vaginal-births
#3
David C Lagrew, Lisa Kane Low, Rita Brennan, Maureen P Corry, Joyce K Edmonds, Brian G Gilpin, Jennifer Frost, Whitney Pinger, Dale P Reisner, Sara Jaffer
Cesarean births and associated morbidity and mortality have reached near epidemic proportions. The National Partnership for Maternal Safety under the guidance of the Council on Patient Safety in Women's Health Care responded by developing a patient safety bundle to reduce the number of primary cesarean births. Safety bundles outline critical practices to implement in every maternity unit. This National Partnership for Maternity Safety bundle, as with other bundles, is organized into four domains: Readiness, Recognition and Prevention, Response, and Reporting and Systems Learning...
February 22, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29471508/protein-hydrolysate-from-turkey-meat-and-optimization-of-its-antioxidant-potential-by-response-surface-methodology
#4
Daoying Wang, Fereidoon Shahidi
The objective of this research was to optimize antioxidant potential of hydrolyzed protein using Flavourzyme assisted hydrolysis of turkey meat and compare the antioxidant activity of hydrolysates from turkey meat, chicken, and beef. Response surface methodology (RSM) was used to determine the optimal Flavourzyme hydrolysis conditions for preparation of hydrolysate from turkey meat, which were at a temperature of 50.09°C, pH of 5.42, and processing time of 1.08 hours. For comparison, antioxidant activities of the hydrolysate from turkey meat, chicken, and beef under the optimum conditions were determined using reducing power, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical cation, hydroxyl radical, and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities...
February 19, 2018: Poultry Science
https://www.readbyqxmd.com/read/29471439/robot-assisted-ligation-of-bronchial-artery-could-be-an-alternative-to-embolization
#5
Bruno Pochulu, Omar Sarsam, Christophe Peillon, Jean-Marc Baste
A 37-year-old patient presented with a self-limiting episode of moderate haemoptysis. Contrast-enhanced chest computed tomography showed a tortuous and dilated right bronchial artery arising from the descending aorta at the level of T6. Therapeutic angiography was attempted, but in the presence of spinal artery arising from the bronchial artery in question, selective embolization was contraindicated due to risk of spinal cord ischaemia. After a multidisciplinary meeting, it was decided to attempt surgery to ligate this pathological artery...
March 1, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29471369/genome-wide-association-study-of-stayability-and-heifer-pregnancy-in-red-angus-cattle
#6
S E Speidel, B A Buckley, R J Boldt, R M Enns, J Lee, M L Spangler, M G Thomas
Reproductive performance is the most important component of cattle production from the standpoint of economic sustainability of commercial beef enterprises. Heifer Pregnancy (HPG) and Stayability (STAY) genetic predictions are two selection tools published by the Red Angus Association of America (RAAA) to assist with improvements in reproductive performance. Given the importance of HPG and STAY to the profitability of commercial beef enterprises, the objective of this study was to identify QTL associated with both HPG and STAY in Red Angus cattle...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471360/adverse-consequences-of-unmet-needs-for-care-in-high-need-high-cost-older-adults
#7
Scott R Beach, Richard Schulz, Esther M Friedman, Juleen Rodakowski, Grant Martsolf, Alton Everette James
Objectives: We explore adverse consequences of unmet needs for care among high-need/high-cost (HNHC) older adults. Method: Interviews with 4,024 community-dwelling older adults with ADL/IADL/mobility disabilities from the 2011 National Health and Aging Trends Study (NHATS). Reports of socio-demographics, disability compensatory strategies, and adverse consequences of unmet needs in the past month were obtained from older adults with multiple chronic conditions (MCC), probable dementia (DEM), and/or near end-of-life (EOL) and compared older adults not meeting these criteria...
February 17, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29471330/converging-and-diverging-needs-between-patients-and-providers-who-are-collecting-and-using-patient-generated-health-data-an-integrative-review
#8
Meghan J Reading, Jacqueline A Merrill
Objective: This integrative review identifies convergent and divergent areas of need for collecting and using patient-generated health data (PGHD) identified by patients and providers (i.e., physicians, nurses, advanced practice nurses, physician assistants, and dietitians). Methods: A systematic search of 9 scholarly databases targeted peer-reviewed studies published after 2010 that reported patients' and/or providers' needs for incorporating PGHD in clinical care...
February 17, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29471177/needs-of-students-seeking-careers-in-communication-sciences-and-disorders-and-barriers-to-their-success
#9
Akiko Fuse
PURPOSE: The purpose of this study was to identify the needs for and barriers to success of underrepresented students in the Communication Sciences and Disorders field and to determine factors linked to student persistence and academic achievement. METHOD: An online survey was completed by 126 undergraduates pursuing graduate studies in Communication Sciences and Disorders. Data were subjected to Mann-Whitney U and Kruskal-Wallis H tests. RESULTS: Survey responses indicated that financial matters exerted the most influence on students' preparation for and number of choices for graduate-school applications...
February 14, 2018: Journal of Communication Disorders
https://www.readbyqxmd.com/read/29471129/issues-in-estimating-probability-of-detection-of-ndt-techniques-a-model-assisted-approach
#10
Vamsi Krishna Rentala, Phani Mylavarapu, Jai Prakash Gautam
In order to successfully implement Damage Tolerance (DT) methodology for aero-engines, Non-Destructive Testing (NDT) techniques are vital for assessing the remaining life of the component. Probability of Detection (POD), a standard measure of NDT reliability, is usually estimated as per MIL-HDBK-1823A standard. Estimation of POD of any NDT technique can be obtained by both experimental and model assisted methods. POD depends on many factors such as material, geometry, defect characteristics, inspection technique, etc...
February 13, 2018: Ultrasonics
https://www.readbyqxmd.com/read/29471114/reference-size-matching-whole-genome-amplification-and-fluorescent-labeling-as-a-method-for-chromosomal-microarray-analysis-of-clinically-actionable-copy-number-alterations-in-formalin-fixed-paraffin-embedded-tumor-tissue
#11
Shelly R Gunn, Shailin Govender, Cynthe L Sims, Aditi Khurana, Samuel Koo, Jayne Scoggin, Mathew W Moore, Philip D Cotter
Cancer genome copy number alterations (CNAs) assist clinicians in selecting targeted therapeutics. Solid tumor CNAs are most commonly evaluated in formalin-fixed, paraffin-embedded (FFPE) tissue by fluorescence in situ hybridization. Although fluorescence in situ hybridization is a sensitive and specific assay for interrogating pre-selected genomic regions, it provides no information about co-existing clinically significant copy number changes. Chromosomal microarray analysis is an alternative DNA-based method for interrogating genome-wide CNAs in solid tumors...
February 19, 2018: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/29471076/daily-pattern-of-energy-distribution-and-weight-loss
#12
Hollie A Raynor, Fan Li, Chelsi Cardoso
Timing of energy intake, a temporal dietary pattern, may enhance health. Eating a greater amount of energy earlier and a smaller amount of energy later in the day, a behavioral circadian rhythm, may assist with chronoenhancement. Chronoenhancement seeks to enhance entrainment (synchronization) of biological and behavioral circadian rhythms. In humans, research reports that eating a greater amount of energy early and a smaller amount of energy later in the day increases dietary induced thermogenesis, improves cardiometabolic outcomes, and enhances weight loss...
February 19, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29470956/metabolomic-insights-into-the-effects-of-thyroid-hormone-on-rana-lithobates-catesbeiana-metamorphosis-using-whole-body-matrix-assisted-laser-desorption-ionization-mass-spectrometry-imaging-maldi-msi
#13
Teesha C Luehr, Emily M Koide, Xiaodong Wang, Jun Han, Christoph H Borchers, Caren C Helbing
Anuran metamorphosis involves the transformation of an aquatic tadpole into a juvenile frog. This process is completely dependent upon thyroid hormones (THs). Although much research has been focused on changes in gene expression programs during this postembryonic developmental period, transitions in the metabolic profiles are relatively poorly understood. Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI) is a technique that generates highly multiplexed mass spectra while retaining spatial location information on a thin tissue section...
February 19, 2018: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29470951/serum-level-of-long-noncoding-rna-h19-as-a-diagnostic-biomarker-of-multiple-myeloma
#14
Yafang Pan, Hongmei Chen, Xianjuan Shen, Xudong Wang, Shaoqing Ju, Meihong Lu, Hui Cong
Circulating long noncoding RNA (lncRNA) H19 has been reported to be a biomarker for cancer monitoring. The purpose of this study was to determine whether serum lncRNA could serve as a novel biomarker for the diagnosis of multiple myeloma (MM) and evaluate its value of clinical application. In our study, the expression of lncRNA H19 was up-regulated in 80 patients with MM and MM cell lines by RT-PCR analysis. Clinicopathological analysis showed the expression level of H19 could assist clinical staging, and the severity of the disease could be roughly determined according to the amount of H19 expressed in the patient serum...
February 19, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29470789/evaluation-of-psychometric-and-linguistic-properties-of-the-italian-adolescent-pain-assessment-scales-a-systematic-review
#15
REVIEW
Flavio Marti, Antonella Paladini, Giustino Varrassi, Roberto Latina
INTRODUCTION: Adolescents' pain experiences are complex and multidimensional, and evaluating pain only from a sensory and affective point of view may be in many instances limiting and inadequate; this is the reason why it is of paramount importance to identify the tools which can better assess the pain experienced by young patients. A person-oriented approach is highly encouraged, as it may better investigate the cognitive and behavioral development typical of this age group. The aim of this review paper is to describe the available tools which are able to adequately assess pain intensity in adolescents, in particular those validated in Italian...
February 22, 2018: Pain and Therapy
https://www.readbyqxmd.com/read/29470720/diagnostic-tools-for-inborn-errors-of-human-immunity-primary-immunodeficiencies-and-immune-dysregulatory-diseases
#16
REVIEW
Annely M Richardson, Ann M Moyer, Linda Hasadsri, Roshini S Abraham
PURPOSE OF REVIEW: The purpose of this review is to provide an overview of diagnostic testing in primary immunodeficiency and immune dysregulatory disorders (PIDDs), particularly focusing on flow cytometry and genetic techniques, utilizing specific examples of PIDDs. RECENT FINDINGS: Flow cytometry remains a vital tool in the diagnosis and monitoring of immunological diseases. Its utility ranges from cellular analysis and specific protein quantitation to functional assays and signaling pathway analysis...
February 22, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29470703/guide-for-health-professionals-addressing-oral-care-for-individuals-in-oncological-treatment-based-on-scientific-evidence
#17
Caroline Gomes Carvalho, João Batista Medeiros-Filho, Meire Coelho Ferreira
OBJECTIVE: Oncological treatment can cause changes in the oral cavity compromising oral functions. The aim of the study was, based on a systematic review, to draft a guide directed at the team of health professionals involved in the oral care of oncological patients. METHODS: A systematic search of the literature was performed for articles published between 2000 and April 2017. Searches were made of electronic databases and hand search. The inclusion criteria were systematic reviews of randomized clinical trials (RCTs) and RCTs published in English, involving pediatric and adult oncological patients and focused on the prevention and treatment of oral complications as well as studies addressing the maintenance of oral health...
February 22, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29470702/the-mutual-benefits-of-research-in-wild-animal-species-and-human-assisted-reproduction
#18
REVIEW
P Comizzoli, E E Paulson, L K McGinnis
Studying the reproductive biology of wild animal species produces knowledge beneficial to their management and conservation. However, wild species also share intriguing similarities in reproductive biology with humans, thereby offering alternative models for better understanding the etiology of infertility and developing innovative treatments. The purpose of this review is to raise awareness in different scientific communities about intriguing connections between wild animals and humans regarding infertility syndromes or improvement of fertility preservation...
February 22, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29470663/miniaturized-dispersive-liquid-liquid-microextraction-and-maldi-ms-using-ionic-liquid-matrices-for-the-detection-of-bacterial-communication-molecules-and-virulence-factors
#19
Jan Leipert, Ingrid Bobis, Sabine Schubert, Helmut Fickenscher, Matthias Leippe, Andreas Tholey
The identification and quantification of molecules involved in bacterial communication are major prerequisites for the understanding of interspecies interactions at the molecular level. We developed a procedure allowing the determination of 2-heptyl-4(1H)-quinolone (HHQ) and 2-heptyl-3-hydroxy-4(1H)-quinolone (PQS) and the virulence factor pyocyanin (PYO) formed by the Gram-negative bacterium Pseudomonas aeruginosa. The method is based on dispersive liquid-liquid microextraction from small supernatant volumes (below 10 μL) followed by quantitative matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS)...
February 22, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29470600/genetic-mapping-populations-for-conducting-high-resolution-trait-mapping-in-plants
#20
James Cockram, Ian Mackay
Fine mapping of quantitative trait loci (QTL) is the route to more detailed molecular characterization and functional studies of the relationship between polymorphism and trait variation. It is also of direct relevance to breeding since it makes QTL more easily integrated into marker-assisted breeding and into genomic selection. Fine mapping requires that marker-trait associations are tested in populations in which large numbers of recombinations have occurred. This can be achieved by increasing the size of mapping populations or by increasing the number of generations of crossing required to create the population...
February 23, 2018: Advances in Biochemical Engineering/biotechnology
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