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https://www.readbyqxmd.com/read/29777899/congenital-dyshormonogenic-hypothyroidism-with-goiter-caused-by-a-sodium-iodide-symporter-slc5a5-mutation-in-a-family-of-shih-tzu-dogs
#1
E A Soler Arias, V A Castillo, J D Garcia, J C Fyfe
An iodide transport defect (ITD) in the thyroid gland was determined to cause congenital dyshormonogenic hypothyroidism with goiter (CDHG) in 2 members of a family of Shih-Tzu dogs. Strikingly, both dogs were also diagnosed with dilated cardiomyopathy at 24 and 1.5 mo of age. The only sign of hypothyroidism was a moderate growth delay in the adult dog. The ITD was recognized by the absence of uptake of technetium-99m in the salivary glands (sg) and goiter observed by scintigraphy. In the same scan, radiopharmaceutical uptake was found in the anterior mediastinum of both dogs and in the right axillary lymph node in the oldest dog...
April 24, 2018: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/29776698/transoral-videolaryngoscopic-surgery-for-papillary-carcinoma-arising-in-lingual-thyroid
#2
Chisato Mogi, Hirotaka Shinomiya, Natsumi Fujii, Tomoyuki Tsuruta, Naruhiko Morita, Tatsuya Furukawa, Masanori Teshima, Maki Kanzawa, Mitsuyoshi Hirokawa, Naoki Otsuki, Ken-Ichi Nibu
Carcinoma arising in lingual thyroid is an extremely rare entity accounting for only 1% of all reported ectopic thyroids. Here, we report a case of carcinoma arising in lingual thyroid, which has been successfully managed by transoral resection and bilateral neck dissections. A lingual mass 4-cm in diameter with calcification was incidentally detected by computed tomography at medical check-up. No thyroid tissue was observed in normal position. Ultrasound examination showed bilateral multiple lymphadenopathies...
May 15, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29756110/agenesis-of-the-isthmus-of-the-thyroid-gland
#3
Uğur Kesici, Sevgi Kesici
The thyroid is an endocrine gland composed of two lobes connected by the isthmus tissue. Thyroid isthmus agenesis is a rare condition, and only a few cases have been reported in the literature. Here, we discuss the case of a 56-year-old female patient in whom agenesis of the thyroid isthmus was discovered incidentally during surgery for a multinodular goitre. When agenesis of the isthmus is found, associated thyroid lobe agenesis and the presence of ectopic thyroid tissue must be considered. In addition, associated autoimmune thyroid nodule, thyroiditis, primary thyroid carcinoma, metastasis, and amyloidosis must be considered in the differential diagnosis...
2018: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29750647/the-etiologies-and-incidences-of-congenital-hypothyroidism-before-and-after-neonatal-tsh-screening-program-implementation-a-study-in-southern-thailand
#4
Somchit Jaruratanasirikul, Jutarat Piriyaphan, Tansit Saengkaew, Waricha Janjindamai, Hutcha Sriplung
BACKGROUND: Congenital hypothyroidism (CH) is one of the common causes of intellectual disability which can be prevented by early detection of an elevated thyroid stimulating hormone (TSH) level in the newborn and by treatment with thyroxine. In Thailand, neonatal TSH screening was implemented nationwide in 2005. The objective of the study was to determine the etiologies and the estimated incidences of CH in southern Thailand before and after the implementation of a neonatal TSH screening program in 2005...
May 11, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29732163/dual-ectopic-thyroid-associated-with-thyroid-hemiagenesis
#5
Shigenori Nakamura, Teruyuki Masuda, Masatoshi Ishimori
We report a case of a 15-year-old girl with a midline neck mass that was first noted 2 or 3 years previously. She had been treated with levothyroxine (L-T4) for congenital hypothyroidism until 11 years of age. Ultrasonography revealed an atrophic right thyroid (1.0 × 1.6 × 2.6 cm in size) and a mass (2.3 × 1.0 × 3.5 cm in size) in the upper part of the neck. No left lobe of the thyroid was detected. On further evaluation, Tc-99m pertechnetate thyroid scintigraphy and CT showed ectopic thyroid tissue in the lingual region and infrahyoid region...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29731804/ectopic-thyroid-in-stomach-a-case-report
#6
Parvin Rajabi, Seyed-Mehdi Eftekhari, Elham Rouhani, Azar Baradaran
An ectopic thyroid is a form of thyroid dysgenesis in which an entire or parts of the thyroid gland may be located in another part of the body than what is the usual place. The most frequent location is the base of tongue. Although most cases are asymptomatic, symptoms related to tumor size and its relationship with surrounding tissues, hormonal dysfunction and seldom malignancy may also occur. Any disease affecting the thyroid gland may involve the ectopic thyroid, including malignancy.
2018: Iranian Journal of Pathology
https://www.readbyqxmd.com/read/29724981/uncommon-right-ventricular-mass-ectopic-thyroid
#7
Yutian Sun, Jing Wang, Dianbo Cao
No abstract text is available yet for this article.
May 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29724805/recognizing-pinhole-parallax-error-for-accurate-localization-of-thyroid-and-parathyroid-pathology
#8
Ismet Sarikaya, Zaina Al-Banna, Ali Baqer
Parallax error is a pitfall of pinhole scintigraphy which causes mislocalization of the objects. It is important to notice this error on pinhole thyroid and parathyroid scintigraphy and obtain additional images with parallel-hole collimator to accurately determine the upper and lower margins of large goiter and nodules and location of the ectopic thyroid tissue and parathyroid adenomas. In this teaching case report we wanted to revisit pinhole parallax error, present pinhole and SPECT/CT images of a case with large hyperactive thyroid nodule and review the literature and potential solutions to this important problem...
May 3, 2018: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29697084/ectopic-thyroid-the-great-mimicker
#9
Yazdan Raji, Supriya Gupta, Darko Pucar, Jayanth H Keshavamurthy
Ectopic thyroid tissue is very rare, but its prevalence increases in those with thyroid pathology. It typically occurs due to aberrant development of the thyroid gland during its migration to the pretracheal region. In this report, there are two cases of mediastinal ectopic thyroid tissue discussed, which were initially considered to be malignancies. The hospital course, diagnostic workup, including the use of computed tomography and positron emission tomography scans, and the characteristic features of the tissue are examined here...
May 2018: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29692520/hemiagenesis-of-thyroid-with-dual-thyroid-ectopia-a-rare-case-report
#10
Pankaj S Jha, Varsha Rote-Kaginalkar, Prashant Titare, Manoj B Jadhav
Developmental defects of the thyroid gland are very rare. The common developmental abnormalities are ectopic thyroid, hemiagenesis and agenesis of thyroid gland. These developmental defects may or may not be associated with deranged thyroid function tests. Ultrasonography (USG) is the initial modality of choice for thyroid hemiagenesis but further evaluation by computed tomography (CT) scan or nuclear scan should be done to look for ectopic thyroid tissue rest. Here, we report a rare case of a 9-year-old female having hemiagenesis of the right thyroid lobe and isthmus along with dual ectopic thyroid tissue at prehyoid and infrahyoid regions of the neck presenting as a midline neck swelling and subclinical hypothyroidism...
January 2018: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29618346/diagnosis-and-management-of-a-mediastinal-ectopic-thyroid-laying-on-the-right-bronchus-case-report-and-review-of-literature
#11
Alessio Metere, Tiziano De Giacomo, Massimo Vergine, Marco Biffoni, Laura Giacomelli
BACKGROUND: The mediastinal ectopic thyroid is very rare, accounting for less than 1% of all cases of ectopic thyroid tissue. The differential diagnoses with other diseases such as lymphomas, thymic tumors and dermoid cysts is mandatory, in fact each one, needs different management and treatment. CASE PRESENTATION: Here, we discuss a rare case of mediastinal ectopic thyroid presenting with a paratracheal mass laying on the right bronchus without symptoms. A 63-year-old male presented with an abnormal well-defined mass along the right paratracheal side, detected by chest x-ray...
April 4, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29595677/the-value-of-scintigraphy-computed-tomography-magnetic-resonance-imaging-and-single-photon-emission-computed-tomography-computed-tomography-for-the-diagnosis-of-ectopic-thyroid-in-the-head-and-neck-a-strobe-compliant-retrospective-study
#12
Feng Xu, Ziyang Shao, Gongxing Yang, Aichun Gu, Mengda Jiang, Yifan Pan, Yubo Ma
Because of its rarity, the exact imaging features of ectopic thyroid are poorly known.To analyze the value of scintigraphy, computed tomography (CT), magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT)/CT in the diagnosis of ectopic thyroid in the head and neck.First, we retrospectively analyzed the scintigraphy, CT, MRI, and SPECT/CT images from 25 masses (22 patients) suspected of head and neck ectopic thyroid from 2006 to 2017 at the Shanghai Ninth People's Hospital. Each mass was imaged by nuclear imaging (scintigraphy with or without SPECT/CT) and radiological exam (CT and/or MRI)...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29593791/histopathological-characterization-and-whole-exome-sequencing-of-ectopic-thyroid-fetal-architecture-in-a-functional-ectopic-gland-from-adult-patient
#13
Rosalinda Yasato Camargo, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, Célia Regina Nogueira, Sonia Iorcansky, Alfio José Tincani, Ana Karina Bezerra, Ester Brust, Fernanda Christtanini Koyama, Anamaria Aranha Camargo, Fernanda Orpinelli R Rego, Pedro Alexandre Favoretto Galante, Geraldo Medeiros-Neto, Ileana Gabriela Sanchez Rubio
Ectopic thyroid results from a migration defect of the developing gland during embryogenesis causing congenital hypothyroidism. But it has also been detected in asymptomatic individuals. This study aimed to investigate the histopathological, functional, and genetic features of human ectopic thyroids. Six samples were histologically examined, and the expression of the specific thyroid proteins was assessed by immunohistochemistry. Two samples were submitted to whole exome sequencing. An oropharynx sample showed immature fetal architecture tissue with clusters or cords of oval thyrocytes and small follicles; one sample exhibited a normal thyroid pattern while four showed colloid goiter...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29575022/prevalence-and-sonographic-features-of-ectopic-thyroidal-thymus-in-children-a-retrospective-analysis
#14
Adalet Elcin Yildiz, Atilla Halil Elhan, Suat Fitoz
PURPOSE: To assess the prevalence of ectopic thyroidal thymus tissue detected by sonography (US) in children and to analyze the US features. METHODS: We retrospectively reviewed images of 216 children who had undergone a thyroid or neck US examination from February 2015 to June 2015. Lesions within or adjacent to the thyroid gland that showed echopatterns consistent with thymic tissue were diagnosed as ectopic thyroidal thymus tissue. Lesions were reviewed according to their side, location, level, size, shape, echo pattern, internal content, and vascularization...
March 25, 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29451347/a-rare-case-of-ectopic-papillary-thyroid-carcinoma-transformed-into-squamous-cell-carcinoma
#15
Hironao Yasuoka, Yasushi Nakamura, Ken-Ichi Yoshida, Toshiro Shimo, Masayuki Tori, Yuuki Matsui, Yasushi Sakamaki, Masahiko Tsujimoto
A rare case of a metastatic ectopic papillary thyroid carcinoma (PTC) of the lung that transformed into a squamous cell carcinoma (SCC) that resembles pulmonary SCC is reported. A subcutaneous ectopic PTC in the left anterior neck area, together with a normal thyroid gland, were excised. The ectopic PTC showed thyroglobulin, TTF-1 and PAX-8 immunoreactivity and a BRAF V600E mutation. During the post-operative follow-up period, a rapidly growing 2 cm nodular lesion in the lower left lobe of the lung was detected...
April 2018: Pathology International
https://www.readbyqxmd.com/read/29381957/ectopic-thyroid-of-the-pancreas-a-case-report-and-literature-review
#16
Aiwen Ma, Hongfeng Liu
RATIONALE: Ectopic thyroid is commonly found in the neck region. Intra-abdominal ectopic thyroid is extremely rare, with only 2 cases reported in the pancreatic region. Very few reports have described detailed imaging findings of intra-abdominal ectopic thyroid. PATIENT CONCERNS: A 73-year-old woman with aggravated recurrent right upper quadrant pain was found to have a retroperitoneal mass at the head of pancreas. Abdominal computed tomography (CT) showed a well-defined, high attenuated (56HU) mass measured of 60 × 50 mm in diameter, that exhibited heterogeneous contrast enhancement throughout the 3 phases...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29367360/recurrence-of-graves-disease-in-ectopic-thyroid-tissue
#17
Kalyna Jakibchuk, Sophia Ali, Julie Samantray
A 40-year-old woman with a history of Graves' disease status postorbital decompression for severe ophthalmopathy underwent total thyroidectomy by a high volume thyroid surgeon in July 2013 with a benign final pathology. Eight months later, she presented with a mass on the right anterior neck that showed minimal growth over time. Her thyroid stimulating immunoglobulin and thyroid-stimulating hormone receptor antibody levels were consistently elevated and increasing. She underwent removal of the neck mass in September 2016...
January 23, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29310383/ectopic-papillary-thyroid-carcinoma-within-a-thyroglossal-duct-cyst-a-case-report
#18
Natascha Roehlen, Szilvia Takacs, Olaf Ebeling, Jochen Seufert, Katharina Laubner
RATIONALE: Ectopic thyroid carcinoma within a thyroglossal duct cyst (TGDCCa) is an extremely rare entity. Thus, there is no unified appropriate therapeutic strategy, and individual approaches are controversial. PATIENTS CONCERNS: We report the case of a 21-year old woman who underwent Sistrunk procedure for a thyroglossal duct cyst (TGDC). DIAGNOSES: During histological evaluation of the resected TGDC a papillary thyroid carcinoma was found...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29238947/thyroid-ectopy-diagnostic-and-therapeutic-challenges-before-and-in-the-era-of-tsh-neonatal-screening
#19
REVIEW
Ewelina Szczepanek-Parulska, Aleksandra Hernik, Marek Ruchała
Despite TSH screening in newborns is currently conducted in most developed countries, patients with thyroid ectopy born before the procedure was introduced or those in whom the screening failed to establish diagnosis, might still appear. In the paper we revise the current state of knowledge regarding the clinical presentation, diagnosis and treatment of patients with thyroid ectopy. As an example, we report diagnostic and therapeutic difficulties in our three patients with thyroid ectopy remaining undiagnosed and untreated during early childhood...
2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/29230334/thyrotoxicosis-associated-with-a-hypopharyngeal-toxic-nodular-thyroid
#20
S Ali Imran, Adam Hinchey, Rob Hart, Martin Bullock, Andrew Ross, Steven Burrell
Ectopic thyroid is a rare developmental anomaly which may be either asymptomatic or present with thyroid dysfunction as well as pressure symptoms. Here we present a novel case of thyrotoxicosis associated with a hypopharyngeal multinodular thyroid in a female. Removal of the ectopic thyroid led to normalization of the thyroid status.
2017: Case Reports in Endocrinology
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