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Diabetes, obesity, hypertension

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https://www.readbyqxmd.com/read/28544753/no-association-between-metabolic-syndrome-and-radiographic-hand-osteoarthritis-data-from-the-framingham-study
#1
Mette P Strand, Tuhina Neogi, Jingbo Niu, David T Felson, Ida K Haugen
OBJECTIVE: To explore whether metabolic syndrome (MetS) and its components are associated with hand OA using longitudinal data from the Framingham study. METHODS: In our cross-sectional analyses we included 1089 persons (age 50-75 years), of whom 785 had 7-year longitudinal radiographs. Of these, 586 with no hand OA at baseline were included in analyses on hand OA incidence. We explored associations between and MetS and its components (central obesity, hypertension, diabetes, triglyceridemia, low high-density lipoprotein) and radiographic hand OA (defined as ≥2 interphalangeal joints with Kellgren-Lawrence grade≥2) using logistic regression analyses with adjustment for age, sex and body mass index (BMI)...
May 23, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28544429/diabetes-and-cardiometabolic-risk-factors-in-cambodia-results-from-two-screening-studies
#2
Julie Wagner, Diana Naranjo, Touch Khun, Serey Seng, Ien Srey Horn, Sakinah Carter Suttiratana, Lim Keuky
BACKGROUND: Despite growing attention to diabetes throughout Asia, data from Southeast Asia are limited. This article reports rates of diabetes, hypertension and obesity in Cambodia. METHODS: Two studies were conducted across different regions of Cambodia: a 2012 screening study across urban, semi-urban and rural areas that used point of care capillary glucose for determination of diabetes (n = 13,997) and a 2005 epidemiological study with random selection from two main urban areas that used oral glucose tolerance tests for determination of diabetes (n = 1,863)...
May 22, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28542517/revisiting-the-discriminatory-accuracy-of-traditional-risk-factors-in-preeclampsia-screening
#3
Merida Rodriguez-Lopez, Philippe Wagner, Raquel Perez-Vicente, Fatima Crispi, Juan Merlo
BACKGROUND: Preeclampsia (PE) is associated with a high risk of perinatal morbidity and mortality. However, there is no consensus in the definition of high-risk women. AIM: To question current definition of high PE risk and propose a definition that considers individual heterogeneity to improves risk classification. METHODS: A stratified analysis by parity was conducted using the Swedish Birth Register between 2002-2010 including 626.600 pregnancies...
2017: PloS One
https://www.readbyqxmd.com/read/28540224/erectile-dysfunction-therapy-in-countries-where-implant-is-economically-not-feasible
#4
REVIEW
Adrián M Garza-Gangemi, Mariano Sotomayor-de Zavaleta
Erectile dysfunction (ED), a frequent complaint in the primary care setting, is strongly associated with obesity, cigarette smoking and other common cardiovascular risk factors like hypertension, diabetes mellitus (DM), lipid disorders and the metabolic syndrome. The prevalence of these cardiovascular disorders is rising at staggering rates in most Latin American countries. ED is a symptom that mainly affects economically productive men (40-70 years of age) potentially causing major psychosocial repercussions and reduced quality of life...
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28540201/cold-dialysis-and-its-impact-on-renal-patients-health-an-evidence-based-mini-review
#5
REVIEW
Giorgos K Sakkas, Argiro A Krase, Christoforos D Giannaki, Christina Karatzaferi
Chronic renal disease is associated with advanced age, diabetes, hypertension, obesity, musculoskeletal problems and cardiovascular disease, the latter being the main cause of mortality in patients receiving haemodialysis (HD). Cooled dialysate (35 °C-36 °C) is recently employed to reduce the incidence of intradialytic hypotension in patients on chronic HD. The studies to date that have evaluated cooled dialysate are limited, however, data suggest that cooled dialysate improves hemodynamic tolerability of dialysis, minimizes hypotension and exerts a protective effect over major organs including the heart and brain...
May 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28540132/more-risks-and-complications-for-elective-spine-surgery-in-morbidly-obese-patients
#6
REVIEW
Nancy E Epstein
BACKGROUND: The vast majority of studies emphasize the greater morbidity/mortality for elective spine surgery in morbidly obese patients. METHODS: This review focuses on the increased morbidity/mortality of performing elective spinal operations in morbidly obese patients. There are two definitions of morbid obesity; a body mass index (BMI) of equal to or greater than 35 plus two major comorbid factors (e.g., hypertension, diabetes, etc.) or a BMI (morbidly obese III) of =≥40 kg/m(2)...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28539724/anti-differentiation-effect-of-b-d-seco-limonoids-of-swietenia-mahogani
#7
Heejung Yang, Mina Choi, Dong Young Lee, Sang Hyun Sung
BACKGROUND: Obesity is a pathological state caused by abnormal or excessive accumulation of fat. Swietenia mahogani JACQ., known as West Indian mahogany, is a medium-sized semi-evergreen tree belonging to Meliaceae. Their seeds are used in Indonesian folk medicine as a treatment for hypertension, diabetes, malaria, and it also has anti-feedant activities. The major components of S. mahogani are B, D-seco limonoids, a type of irregular triterpenes are well known. OBJECTIVE: We tried to find the bioactive components, which have the inhibitory activity on adipocyte differentiation from the seeds of S...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28539091/in-silico-identification-of-potential-drug-compound-against-peroxisome-proliferator-activated-receptor-gamma-by-virtual-screening-and-toxicity-studies-for-treatment-of-diabetic-nephropathy
#8
Smrita Singh, Aparajita Mohanty
Diabetic Nephropathy is a serious complication of Diabetes Mellitus. Current therapeutic strategies of Diabetic Nephropathy are based on control of modifiable risks like hypertension, glucose levels, and dyslipidemia. Peroxisome proliferator activated receptor-gamma (PPAR-γ) is implicated in several metabolic syndromes including Diabetic Nephropathy, besides obesity, insulin insensitivity, dislipidemia, inflammation and hypertension. In the present study, virtual screening of 617 compounds from two different public databases was done against PPAR- γ with an objective to find a possible lead compound...
May 24, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28538855/-methodology-for-estimating-total-direct-costs-of-comprehensive-care-for-non-communicable-diseases
#9
Nancy Castillo, Miguel Malo, Nilda Villacres, José Chauca, Víctor Cornetero, Karin Roedel de Flores, Rafaela Tapia, Raúl Ríos
RESUMEN Diseases like diabetes mellitus (DM) and hypertension (HT) generate high costs and are the most common cause of mortality in the Americas. In the case of Peru, given demographic and epidemiological changes, particularly the alarming increase in overweight and obesity, the burden of these diseases is constantly increasing, resulting in the need to budget more financial resources to the health services. The total care costs of these diseases and their complications represent a financial burden that should be considered very carefully by health institutions when they draft their budgets...
January 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28537562/impact-of-bariatric-surgery-on-non-alcoholic-fatty-liver-disease
#10
Piotr Major, Michał Pędziwiatr, Mateusz Rubinkiewicz, Maciej Stanek, Anna Głuszewska, Magdalena Pisarska, Piotr Małczak, Andrzej Budzyński, Piotr Budzyński
Introduction; p to 300 million people have the body mass index (BMI) greater than 30 kg/m2. Obesity is the cause of many serious diseases, such as type 2 diabetes, hypertension, and non-alcoholic fatty liver disease (NAFLD). Bariatric surgery is the only effective method of achieving weight loss in patients with morbid obesity. OBJECTIVES: The aim of the study was to assess the impact of bariatric surgery on non-alcoholic fatty liver disease in patients operated on due to morbid obesity...
April 30, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28535567/radiation-dose-and-procedure-time-for-994-ct-guided-spine-pain-control-procedures
#11
Matthew S Lazarus, Rebecca B Forman, Alan L Brook, Todd S Miller
BACKGROUND: Image guidance for spine pain control procedures, including epidural steroid injection, nerve root block, and facet block, can be performed with either computed tomography (CT) or conventional fluoroscopy. CT has the advantage of improved anatomic localization and use of air for contrast; however, there are concerns that CT leads to higher radiation dose and longer procedure time. OBJECTIVE: To evaluate procedure time and radiation dose for multiple types of spine pain control procedures performed under CT guidance...
May 2017: Pain Physician
https://www.readbyqxmd.com/read/28534318/association-between-inflammatory-skin-disease-and-cardiovascular-and-cerebrovascular-co-morbidities-in-us-adults-analysis-of-nationwide-inpatient-sample-data
#12
Michael C Kwa, Jonathan I Silverberg
BACKGROUND: Psoriasis, atopic dermatitis or eczema (AD-E), pemphigus, bullous pemphigoid (BP), and hidradenitis are chronic inflammatory skin disorders associated with systemic immune activation, considerable symptom burden, stigma, functional disturbances, and mental health symptoms. All of these might increase cardiovascular risk. OBJECTIVE: The objective of this study was to determine whether these inflammatory skin diseases are associated with increased cardiovascular/cerebrovascular risk and/or disease...
May 22, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28530520/cardiovascular-disease-and-gout-real-world-experience-evaluating-patient-characteristics-treatment-patterns-and-health-care-utilization
#13
Michael H Pillinger, Sripal Bangalore, Alyssa B Klein, Scott Baumgartner, Robert Morlock
BACKGROUND: Gout, hyperuricemia, and cardiovascular disease (CVD) are prevalent conditions in the United States, and while they share common risk factors such as obesity, hypertension, hypercholesterolemia, and type 2 diabetes mellitus, relatively little is known about what patient and disease characteristics may link CVD with hyperuricemia and gout and how the presence of both diseases affects management decisions differently than for patients with gout alone. OBJECTIVE: To identify differences in patient characteristics, patterns of urate-lowering therapy (ULT) use, and gout control in gout patients with and without cardiovascular comorbidity...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28529823/obesity-and-sexual-abuse-in-american-indians-and-alaska-natives
#14
James A Levine, Shelly K McCrady-Spitzer, William Bighorse
Mainstream American culture frequently minimizes the prevalence and significance of sexual abuse. Unfortunately, this denial of extensive victimization of women is also present in many underserved populations. In June 2007, Amnesty International released its report on sexual abuse in indigenous women, which states that, "One in three Native American or Alaska Native women will be raped at some point in their lives. Most do not seek justice because they know they will be met with inaction or indifference." This report highlighted an infrequently discussed issue namely, very high levels of sexual abuse in Native American and Alaska Native women...
August 2016: Journal of Obesity & Weight Loss Therapy
https://www.readbyqxmd.com/read/28528703/does-fitness-improve-the-cardiovascular-risk-profile-in-obese-subjects
#15
H Halland, M T Lønnebakken, S Saeed, H Midtbø, D Cramariuc, E Gerdts
BACKGROUND AND AIMS: Good cardiorespiratory fitness has been suggested to reduce the risk of cardiovascular disease in obesity. We explored the association of fitness with the prevalences of major cardiovascular risk factor like hypertension (HT), diabetes and metabolic syndrome (MetS) in overweight and obese subjects. METHODS AND RESULTS: Clinical data from 491 participants in the FAT associated CardiOvasculaR dysfunction (FATCOR) study were analyzed. Physical fitness was assessed by ergospirometry, and subjects with at least good level of performance for age and sex were classified as fit...
April 26, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28526961/simultaneous-conversion-of-gastric-band-to-sleeve-gastrectomy-is-associated-with-increased-postoperative-complications-an-analysis-of-the-american-college-of-surgeons-national-surgical-quality-improvement-program
#16
Zachary C Dietch, Bruce D Schirmer, Peter T Hallowell
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) has gained popularity for the treatment of morbid obesity as gastric banding (BAND) has fallen out of favor. As a result, simultaneous conversion (CONV) of BAND to LSG is commonly performed. We hypothesized that CONV is associated with higher 30-day risk-adjusted serious morbidity. METHODS: Preoperative characteristics and 30-day outcomes from the American College of Surgeons National Surgical Quality Improvement Program Participant Use Files 2010-2014 were selected for patients who underwent LSG...
May 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28523847/sex-differences-in-cardiovascular-risk-profiles-of-ischemic-stroke-patients-with-diabetes-in-the-greater-cincinnati-northern-kentucky-stroke-study
#17
Tracy E Madsen, Jane C Khoury, Kathleen A Alwell, Charles J Moomaw, Stacie L Demel, Matthew L Flaherty, Daniel Woo, Jason Mackey, Felipe De Los Rios La Rosa, Sharyl Martini, Simona Ferioli, Opeolu Adeoye, Pooja Khatri, Brett M Kissela, Dawn Kleindorfer
BACKGROUND: We aimed to compare sex-specific associations between cardiovascular risk factors and diabetes mellitus (DM) among patients with acute ischemic stroke (AIS) in the Greater Cincinnati/Northern Kentucky Stroke Study (GCNKSS). METHODS: The GCNKSS ascertained AIS cases in 2005 and 2010 among adult (age ≥20 years) residents of a biracial population of 1.3 million. Past and current stroke risk factors were compared between those with and without DM using chi-square and multiple logistic regression to examine sex-specific profiles...
May 18, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28522788/effects-of-bariatric-surgery-on-cardiovascular-risk-factors-among-morbidly-obese-patients
#18
Piotr Major, Aleksandra Kowalczuk, Michał Wysocki, Sonia Osadnik, Michał Pędziwiatr, Anna Głuszewska, Magdalena Pisarska, Piotr Małczak, Anna Lasek, Michał Kisielewski, Andrzej Budzyński
AIM OF THE STUDY: The aim of this study was to evaluate the influence of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric by-pass on risk factors of cardiovascular diseases. MATERIAL AND METHODS: We analyzed prospectively collected data of patients operated for morbid obesity who were qualified for laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric by-pass (LRYGB). Risk factors for wyłączecardiovascular diseases were assessed with the SCORE scale and both full and hard Framingham cardiovascular risk scores (FCRs)...
February 28, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28522656/comparison-between-different-measures-of-body-fat-with-kidney-function-decline-and-incident-ckd
#19
Magdalena Madero, Ronit Katz, Rachel Murphy, Anne Newman, Kushang Patel, Joachim Ix, Carmen Peralta, Suzanne Satterfield, Linda Fried, Michael Shlipak, Mark Sarnak
BACKGROUND AND OBJECTIVES: Although anthropometric measures of body fat are associated with development of CKD, they may not be able to distinguish between various forms of fat and therefore may be less accurate than computed tomography (CT) measures. We compared the association of CT and anthropometric measures of obesity with kidney outcomes in the Health Aging and Body Composition Study. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Participants were recruited from March of 1997 through July of 1998...
May 18, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28522093/sleep-duration-associated-with-cardiovascular-conditions-among-adult-nevadans
#20
Brianna L Pergola, Sheniz Moonie, Jennifer Pharr, Timothy Bungum, Julia L Anderson
BACKGROUND: Associations between sleep duration and cardiovascular conditions have been inconsistent. Both short and long sleep duration are associated with increased risk for diabetes, hypertension, obesity, high cholesterol, depression, and overall metabolic dysfunction; all of which are cardiovascular disease risk factors. This study aimed to determine if deficient or excessive sleep duration is associated with cardiovascular conditions. METHODS: Data were obtained from the 2013 Behavioral Risk Factor Surveillance System for the state of Nevada...
June 2017: Sleep Medicine
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