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https://www.readbyqxmd.com/read/29785136/psychological-factors-as-predictors-of-early-postoperative-pain-after-open-nephrectomy
#1
Ana Mimic, Carsten Bantel, Jelena Jovicic, Branko Mimic, Darija Kisic-Tepavcevic, Otas Durutovic, Nebojsa Ladjevic
Purpose: There is an increasing interest in the identification of predictors for individual responses to analgesics and surgical pain. In this study, we aimed to determine psychological factors that might contribute to this response. We hence investigated patients undergoing a standardized surgical intervention (open nephrectomy). Patients and methods: Between May 2014 and April 2015, we conducted a prospective observational cohort study. The following psychological tests were administered preoperatively: Mini-Mental State Examination, Amsterdam Preoperative Anxiety and Information Scale (APAIS), Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, and Pain Catastrophizing Scale...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29766002/influence-of-vitamin-d-receptor-gene-polymorphisms-on-response-to-pegylated-interferon-in-chronic-hepatitis-b-egyptian-patients
#2
Gomaa Mostafa-Hedeab, Dina Sabry, Ghada Mostafa Abdelaziz, Manal Ewaiss, Nagla Adli, Wael Fathy
Background: We explored the effect of vitamin D receptor gene ( VDR ) polymorphisms in response to PEG-IFN treatment in Egyptian chronic hepatitis B (CHB) patients. Methods: Two hundred hepatitis B virus (HBV) patients (42.3±10.7 years) on PEG-IFN α-2a (180 µg /kg for 48 weeks) and one hundred control subjects (37.3 ±12 years) were enrolled in the study. Vitamin D levels and hepatitis B surface antigen (HBsAg) expression were assessed by ELISA. VDR polymorphisms FokI T>C (rs 10735810), BsmI A>G (rs 1544410), ApaI (rs7975253), and TaqI C>T (rs 731236), were genotyped using real-time PCR...
April 2018: Reports of Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/29728923/association-between-polymorphisms-in-vitamin-d-receptor-gene-and-adolescent-idiopathic-scoliosis-a-meta-analysis
#3
Jun Dai, Zheng-Tao Lv, Jun-Ming Huang, Peng Cheng, Huang Fang, An-Min Chen
PURPOSE: This meta-analysis was performed to clarify whether the two single nucleotide polymorphisms (ApaI and BsmI) in vitamin D receptor (VDR) gene conferred susceptibility to adolescent idiopathic scoliosis (AIS). METHODS: A comprehensive literature search in five online databases (PubMed, EMBASE, ISI Web of Science, CNKI, and Wanfang) was performed to identify studies that analyzed the association between VDR gene polymorphisms and risk of AIS. Observational studies met the predetermined inclusion criteria were selected for meta-analysis...
May 4, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29727015/association-of-vdr-gene-polymorphisms-and-22-bp-deletions-in-the-promoter-region-of-tlr2%C3%AE-22-196-174-with-increased-risk-of-pulmonary-tuberculosis-a-case-control-study-in-tea-garden-communities-of-assam
#4
Kangjam Rekha Devi, Kaustab Mukherjee, Pradipta Kumar Chelleng, Simanta Kalita, Upasana Das, Kanwar Narain
BACKGROUND: A high number of pulmonary tuberculosis (PTB) cases have been reported from tea garden communities of Assam. Till date, no molecular epidemiological study was performed to investigate the association of candidate gene(s) with the risk PTB in this region. The present case-control study was aimed to investigate the association of vitamin D receptor (VDR) gene polymorphisms and 22 bp deletion in the promoter region of toll-like receptor 2 (TLR2) gene with the risk of PTB in tea garden communities of Assam...
May 4, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29705233/association-of-vitamin-d-receptor-gene-taqi-bsmi-foki-and-apai-polymorphisms-and-susceptibility-to-hallux-valgus-in-the-chinese-population
#5
Tianqi Tao, Yiqiu Jiang, Wang Li, Yang Li, Jing Du, Jianchao Gui
Previous studies have indicated that vitamin D receptor (VDR) TaqI, BsmI, FokI and ApaI gene polymorphisms are associated with the risk of skeletal malformations with inflammation. However, the potential association of VDR gene polymorphisms with the susceptibility to hallux valgus remains unclear. To clarify this association, we compared the genotypes of 228 patients with hallux valgus with those of 200 controls using the Multiplex SNaPshot system. The χ2 test was used to compare the allele and genotype frequencies between groups, and p ≤ ...
April 25, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29626332/benzalkonium-chloride-tolerance-of-listeria-monocytogenes-strains-isolated-from-a-meat-processing-facility-is-related-to-presence-of-plasmid-borne-bcrabc-cassette
#6
Jana Minarovičová, Adriana Véghová, Mária Mikulášová, Romana Chovanová, Katarína Šoltýs, Hana Drahovská, Eva Kaclíková
Listeria monocytogenes is a serious foodborne pathogen capable of persisting in food processing environments. Tolerance to disinfectants used in industrial settings constitutes an important factor of Listeria survival. In the present study, the mechanism of tolerance to benzalkonium chloride (BAC) was investigated in 77 L. monocytogenes isolates from a meat facility. By PCR approach, the mdrL and lde chromosomal efflux pump genes were detected in all isolates. No isolate was positive for qacH and emrE genes...
April 6, 2018: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29624920/lack-of-association-between-vitamin-d-receptor-bsmi-apai-polymorphisms-and-osteoporosis-risk-a-pooled-analysis-on-chinese-individuals
#7
Qing-Xian Wang, Shi-Meng Zhao, Ya-Bin Zhou, Cheng Zhang
BACKGROUND: As for the association between vitamin D receptor (VDR) gene polymorphisms and osteoporosis, the current results have yielded conflicts. Therefore, we performed a pooled analysis based on Chinese individuals to provide comprehensive data on the association between VDR BsmI, ApaI, Tru9I polymorphisms and osteoporosis risk. METHODS: Studies were identified using PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure and Chinese Biology Medicine databases through to January 2017...
April 6, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29589202/the-impact-of-five-vdr-polymorphisms-on-multiple-sclerosis-risk-and-progression-a-case-control-and-genotype-phenotype-study
#8
Pavel Křenek, Yvonne Benešová, Julie Bienertová-Vašků, Anna Vašků
Vitamin D receptor polymorphisms have been the target of many studies focusing on multiple sclerosis. However, previously reported results have been inconclusive. The objective of this study was to investigate the association between five vitamin D receptor polymorphisms (EcoRV, FokI, ApaI, TaqI, and BsmI) and multiple sclerosis susceptibility and its course. The study was carried out as a case-control and genotype-phenotype study, consisted of 296 Czech multiple sclerosis patients and 135 healthy controls...
March 28, 2018: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/29570410/impact-of-the-arizona-nexss-winter-school-on-astrobiology-knowledge-and-attitudes
#9
Michael Burnam-Fink, Steven J Desch, Daniella Scalice, Hilarie Davis, Cierra J Huff, Dániel Apai
Astrobiology is an inherently interdisciplinary area of study, demanding communication across multiple fields: astronomy, geochemistry, planetary science, and so on. Successful communication requires that researchers be aware of the basic findings, open questions, and tools and techniques of allied fields and possess an appreciation and respect for what these fields consider good science. To facilitate this communication between early-career researchers, the Arizona NExSS Winter School was hosted in February 2016, bringing together graduate students and postdoctoral researchers from backgrounds spanning the field of astrobiology...
March 2018: Astrobiology
https://www.readbyqxmd.com/read/29560132/associations-between-vdr-gene-polymorphisms-and-colorectal-cancer-susceptibility-an-updated-meta-analysis-based-on-39-case-control-studies
#10
Zhipeng Pan, Mengya Chen, Xingxing Hu, Hua Wang, Jiajia Yang, Congjun Zhang, Faming Pan, Guoping Sun
Background: Recent studies have reported the associations between vitamin D receptor ( VDR ) polymorphisms and colorectal cancer (CRC), but the results were not always consistent. This meta-analysis aims to evaluate whether VDR polymorphisms are associated with CRC susceptibility. Materials And Methods: Studies on the associations between VDR polymorphisms and CRC were retrieved from the Web of Science, PubMed, the Chinese Biomedical Database (CBM), Chinese National Knowledge Infrastructure (CNKI) and Wanfang (Chinese) databases...
February 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29559350/association-of-vitamin-d-receptor-gene-polymorphism-taqi-and-apa1-with-bone-mineral-density-in-north-indian-postmenopausal-women
#11
Israr Ahmad, Tabrez Jafar, Farzana Mahdi, Keerti Ameta, Md Arshad, Siddharth Kumar Das, Shah Waliullah, Imran Rizvi, Abbas Ali Mahdi
Vitamin D receptor (VDR) gene has an important role as a candidate gene for the regulation of bone mass in osteoporosis. However, its association with bone mineral density (BMD) is controversial and has not been established in different ethnic populations. To enhance the understanding of VDR gene polymorphism in the context of BMD, we investigated the plausible genetic association of TaqI and ApaI polymorphism with BMD in North Indian postmenopausal women with osteoporosis.254 osteoporotic women (Age 55.82 ± 6...
March 17, 2018: Gene
https://www.readbyqxmd.com/read/29544394/association-of-vitamin-d-receptor-gene-taqi-foki-and-apai-variants-with-arteriovenous-fistula-failure-in-hemodialysis-patients
#12
Can Huzmeli, Gokhan Bagci, Ferhan Candan, Binnur Bagci, Lale Akkaya, Mansur Kayatas
PURPOSE: We investigated the influence of the vitamin D receptor gene TaqI (rs731236), ApaI (rs7975232), and FokI (rs2228570) polymorphisms in arteriovenous fistula failure in hemodialysis patients. METHODS: This study was carried out with 54 patients who experienced two or more fistula failures in the late period after arteriovenous fistula operation and 58 control patients with no history of arteriovenous fistula failure in 3 years or longer. The polymerase chain reaction-restriction fragment length polymorphism method was used to determine the vitamin D receptor TaqI, FokI, and ApaI polymorphisms...
May 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29480871/association-of-vitamin-d-receptor-bsmi-rs1544410-and-apai-rs7975232-polymorphisms-with-susceptibility-to-adolescent-idiopathic-scoliosis-a-systematic-review-and-meta-analysis
#13
REVIEW
Xin Yin, Huadong Wang, Jidong Guo, Liang Zhang, Yupeng Zhang, Li Li, Shuxun Hou
BACKGROUND: AIS is the most common spinal deformity disease, yet its etiology remains uncertain. Significant associations have been found between AIS risk and vitamin D receptor (VDR) gene polymorphisms; however, some of these results are controversial. The aim of this study was to determine whether VDR BsmI rs1544410 and ApaI rs7975232 polymorphisms are correlated with AIS. METHODS: Databases, including PubMed, EMBASE, Web of Science, the Cochrane Library, the Chinese Biomedical Literature Database, and the Wanfang Database, were systematically searched, and eligible case-control studies that explored the association of VDR (BsmI and ApaI) and the susceptibility to AIS were selected...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29468338/vitamin-d-receptor-foki-taqi-and-apai-polymorphisms-and-susceptibility-to-systemic-lupus-erythematosus-an-updated-meta-analysis
#14
Sang-Cheol Bae, Young Ho Lee
This study aimed to explore whether vitamin D receptor (VDR) polymorphisms are associated with susceptibility to systemic lupus erythematosus (SLE). Meta-analyses were conducted to determine the associations between the VDR FokI, TaqI, and ApaI polymorphisms and SLE in all subjects and each ethnic group. A total of 12 studies were considered in the meta-analysis, which involved 1974 patients and 2506 controls. Meta-analysis of the VDR FokI polymorphism showed no association between SLE and the FokI F allele in all study subjects (OR = 1...
February 21, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29467039/influence-of-lifestyle-characteristics-and-vdr-polymorphisms-as-risk-factors-for-intervertebral-disc-degeneration-a-case-control-study
#15
Luiz Angelo Vieira, Aline Amaro Dos Santos, Carla Peluso, Caio Parente Barbosa, Bianca Bianco, Luciano Miller Reis Rodrigues
BACKGROUND: Intervertebral disc degeneration (DD) is an important cause of low back pain and its precise aetiology is not fully understood, being attributed to cumulative environmental, biomechanical and genetic effects. The vitamin D plays a key role in regulation of calcium homeostasis and bone mineralization, exerting its biological activities by binding to a high-affinity receptor (VDR). Polymorphisms in VDR gene were previously associated with DD process, however with conflicting results...
February 21, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29465575/impact-of-vitamin-d-receptor-and-binding-protein-gene-polymorphisms-in-clinical-and-laboratory-data-of-hcv-patients-cross-sectional-study
#16
Letícia de Paula Scalioni, Betânia Rodrigues Dos Santos, Poli Mara Spritzer, Cristiane Alves Villela-Nogueira, Lia Laura Lewis-Ximenez, Priscila Pollo-Flores, Eliane Bordalo Cathalá Esberard, Carlos Eduardo Brandão-Mello, Elisabeth Lampe, Livia Melo Villar
Potential relationship of vitamin D, vitamin D receptor (VDR), and vitamin D binding protein (DBP) have been suggested in the pathophysiology of hepatitis C virus (HCV) infection. The aim of this observational study is to determine vitamin D levels, and VDR and DBP genetic polymorphism according demographic and laboratory data in chronic HCV patients (CHC).A total of 148 CHC patients gave serum samples for testing 25-hydroxyvitamin D (25 (OH)D) level by immunochemiluminometric assay (<20 ng/mL defined as deficient) and donated blood samples to allelic discrimination analysis using TaqMan assays...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29391820/relationship-of-vitamin-d-receptor-gene-polymorphisms-in-helicobacter-pylori-gastric-patients
#17
Dinelma de Jesus Martins, Gyselly Cb Matos, Rosane Sp Loiola, Vivian D'Annibale, Tereza Corvelo
Purpose: The present study aimed to investigate the association between the human VDR gene and Helicobacter pylori infection. Patients and methods: A cross-sectional study was conducted on 208 adult patients with upper gastrointestinal symptoms. Gastric biopsy specimens were obtained from each patient for molecular DNA and histological examination. Patients were genotyped for VDR gene polymorphisms using polymerase chain reaction and restriction fragment length polymorphism analysis...
2018: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/29388852/associations-between-vitamin-d-receptor-polymorphisms-and-susceptibility-to-behcet-s-disease-a-meta-analysis
#18
Zahra Mirfeizi, Samira Tabaei, Yalda Ravanshad, Kamila Hashemzadeh, Elahe Kharazmi, Hassan Mehrad-Majd
BACKGROUND: The vitamin D receptor (VDR) gene polymorphisms have been reported to be related to the development of Behcet's disease (BD). However, the results have been inconsistent among diverse populations. Therefore, this comprehensive meta-analysis has been designed to assess a more accurate association between VDR polymorphisms and BD susceptibility. METHODS: An electronic literature search was conducted to identify eligible studies. Pooled odds ratios (OR) with corresponding 95% confidence interval (CI) were calculated in different genetic models to assess this association...
May 2018: Immunological Investigations
https://www.readbyqxmd.com/read/29384117/vitamin-d-receptor-variants-and-uncontrolled-asthma
#19
K Hutchinson, C P Kerley, J Faul, P Greally, D Coghlan, M Louw, B Elnazir, Y Rochev
Background. Asthma is a common childhood respiratory disease, affecting around 20% of Irish children. In other populations, vitamin D receptor (VDR) polymorphisms have been associated with asthma risk. We aimed to investigate the association between 2 VDR polymorphisms and uncontrolled paediatric asthma. Methods. 44 asthmatic children and 57 healthy volunteers were studied. The VDR TaqI gene variant in exon 9 (T/C) (rs731236) and ApaI (rs7975232) in intron 8 (C/T) were determined, using TaqMan® Assays. The lung function, serum 25-hydroxyvitamin D (25OHD) levels and other biomarkers of allergy, immunity, airway and systemic inflammation were as-sessed...
November 28, 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29343720/associations-between-vdr-gene-polymorphisms-and-osteoporosis-risk-and-bone-mineral-density-in-postmenopausal-women-a-systematic-review-and-meta-analysis
#20
Liang Zhang, Xin Yin, Jingcheng Wang, Daolinag Xu, Yongxiang Wang, Jiandong Yang, Yuping Tao, Shengfei Zhang, Xinmin Feng, Caifeng Yan
Results on the relationships between vitamin D receptor (VDR) gene polymorphisms and postmenopausal osteoporosis (PMOP) susceptibility and bone mineral density (BMD) are conflicting. The aim of the study is to identify more eligible studies that calculated pooled OR and WMD with 95% CI to assess their associations. Overall, there were significant correlations between VDR ApaI, VDR FokI and PMOP susceptibility. Subgroup analysis showed that VDR ApaI polymorphism significantly decreased the osteoporosis risk in Caucasian postmenopausal women...
January 17, 2018: Scientific Reports
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