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https://www.readbyqxmd.com/read/29302018/injuries-and-envenomation-by-exotic-pets-in-hong-kong
#1
V Ch Ng, A Ch Lit, O F Wong, M L Tse, H T Fung
INTRODUCTION: Exotic pets are increasingly popular in Hong Kong and include fish, amphibians, reptiles, and arthropods. Some of these exotic animals are venomous and may cause injuries and envenomation to their owners. The clinical experience of emergency physicians in the management of injuries and envenomation by these exotic animals is limited. We reviewed the clinical features and outcomes of injuries and envenomation by exotic pets recorded by the Hong Kong Poison Information Centre...
January 5, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29299445/the-management-of-a-blood-donor-bitten-by-a-snake
#2
REVIEW
Giuseppe Marano, Massimo Franchini, Liviana Catalano, Stefania Vaglio, Simonetta Pupella, Giancarlo M Liumbruno
The worldwide burden of snakebite is high and venomous snakes are found in many regions of the world and are a threat to public health. In Italy, for instance, viper bites are an infrequent but not negligible event. Although people who have been bitten by a snake rarely wish to donate blood within a "short" time, it is however important to evaluate their eligibility to donate blood or blood components as their donation could be a problem for donor management, especially if a specific policy is not in place...
December 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29289802/epidemiological-profile-of-snake-bite-cases-from-haryana-a-five-year-2011-2015-retrospective-study
#3
Saurabh Bhargava, Ramanjeet Kaur, Rajvinder Singh
Varieties of venomous snakes inhabit in the world which accidentally take thousands of human lives every year. This severe medical emergency constantly persuades national and international health agencies to look at efficient epidemiological profiling of snake-bite cases for the proper management of this sympathetic problem. Establishing the accurate database of snake-bite in humans from different localities of India may perhaps lack certainty due to few inevitable reasons such as consideration of this problem as less emergent problem in disparity to pesticide poisoning, difficulty in the accessibility to rural and tribal areas where chances of snake-bite remain ceiling, lack of inspiring models of snake-bite management training, reduced reporting system, and pitiable maintenance of hospital data in India...
December 20, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29285352/evidence-for-in-vitro-antiophidian-properties-of-aqueous-buds-extract-of-eucalyptus-against-montivipera-bornmuelleri-venom
#4
Joseph Khoury, Ranin Dabbousy, Riyad Sadek, Sayed Antoun, Walid Hleihel, Christian Legros, Ziad Fajloun
Because snake venoms are complex mixtures of bioactive molecules, snake bites produce a large panel of symptoms which cannot be totally prevented by current antivenoms. Thus investigating plant extracts for antivenomics therapy approaches seemed relevant. Here, we evaluated the potency of the aqueous Buds extract of Eucalyptus (ABEE) to counteract the main enzymatic activities of Montivipera bornmuelleri venom. We showed that ABEE efficiently counteracts the proteolytic, Phospholipases A2 (PLA2), and L-aminoacid oxidase activities (LAAO) of M...
2017: Journal of Venom Research
https://www.readbyqxmd.com/read/29279485/clinical-condition-and-management-of-114-mamushi-gloydius-blomhoffii-bites-in-a-general-hospital-in-japan
#5
Takahito Chiba, Hidenobu Koga, Nanae Kimura, Maho Murata, Shunichi Jinnai, Asako Suenaga, Futoshi Kohda, Masutaka Furue
Objective Mamushi (Gloydius blomhoffii) snakebite is the most common type of snake injury in Japan and is also seen in China and Korea. Although the components of Mamushi venom have been investigated, epidemiological and clinical descriptions still remain limited in the English literature. The aim of this study was to review the clinical features and management of patients with injuries related to Mamushi snakebites. Methods We conducted a retrospective examination of 114 Mamushi snakebite cases encountered at a general hospital in Japan from January 2004 to November 2016...
December 27, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29260951/-ulnar-artery-pseudoaneurysm-and-compartment-syndrome-formation-after-snake-bite-to-the-left-forearm-by-lan-pin-et%C3%A2-al-clin-toxicol-phila-2017-nov-10
#6
Chin-Lung Cheng, Liao-Chun Chiang, Cheng-Hsuan Ho, Po-Yu Liu, Chih-Sheng Lai, Kuo-Lung Lai, Wen-Loung Lin, Yan-Chiao Mao
No abstract text is available yet for this article.
December 20, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/29234603/a-retrospective-study-of-clinico-epidemiological-profile-of-snakebite-related-deaths-at-a-tertiary-care-hospital-in-midnapore-west-bengal-india
#7
Rituparna Ghosh, Koushik Mana, Kripasindhu Gantait, Sumana Sarkhel
Objective: Snakebite is one of the neglected tropical diseases that World Health Organization (WHO) aimed to eradicate. The objective of the study is to investigate the mortality and morbidity due to snakebite at Midnapore Medical College & Hospital in Paschim Medinipur district, West Bengal, India. Methods & materials: This is a record-based, retrospective, descriptive epidemiological study conducted from January 2012 to December 2016 at Midnapore Medical College and Hospital(MMCH), Paschim Medinipur district, West Bengal...
2018: Toxicology Reports
https://www.readbyqxmd.com/read/29207729/comparison-of-different-dosing-protocols-of-anti-snake-venom-asv-in-snake-bite-cases
#8
B R Daswani, A S Chandanwale, D B Kadam, B B Ghongane, V S Ghorpade, H C Manu
Introduction: Considering the cost of Anti-Snake Venom (ASV) and irregularity in its supply, there is often a need to curtail doses of ASV, despite guidelines for management of snake bite. During June 2013 to September 2013, when ASV was in short supply, our institutional committee reviewed the overall hospital statistics of snake bite cases as well as scientific literature and formulated a working modified protocol that used low dose of ASV in snake bite cases. Aim: To retrospectively analyse and compare the modified ASV protocol versus conventional ASV protocol with respect to outcome, number of ASV vials required, duration of stay in the hospital/ ICU, and additional supportive interventions needed...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29207467/review-of-ethnomedicinal-uses-phytochemistry-and-pharmacological-properties-of-euclea-natalensis-a-dc
#9
REVIEW
Alfred Maroyi
Euclea natalensis is traditionally used as herbal medicine for several human diseases and ailments in tropical Africa. This study reviews information on ethnomedicinal uses, botany, phytochemical constituents, pharmacology and toxicity of E. natalensis. Results of this study are based on literature search from several sources including electronic databases, books, book chapters, websites, theses and conference proceedings. This study showed that E. natalensis is used as traditional medicine in 57.1% of the countries where it is indigenous...
December 2, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29179990/snakebite-by-micrurus-averyi-schmidt-1939-in-the-brazilian-amazon-basin-case-report-coral-snakebite-by-micrurus-averyi
#10
REVIEW
Iran Mendonça da Silva, Jorge Contreras Bernal, Pedro Ferreira Gonçalves Bisneto, Antônio Magela Tavares, Valéria Mourão de Moura, Claudio S Monteiro-Junior, Rima Raad, Paulo Sergio Bernarde, Jacqueline de Almeida Gonçalves Sachett, Wuelton Marcelo Monteiro
Micrurus snakes, commonly known as coral snakes, are responsible for 0.4% of the snakebites envenomings in Brazil. In this report, we describe a case of envenoming by Micrurus averyi, the black-headed coral snake, recorded in the western Brazilian Amazon. To the best of our knowledge, this is the first published case perpetrated by this species. The major complaint of the patient was an intense local pain and paresthesia. Examination of the bite site revealed edema extending from the left foot up the left leg that was accompanied by erythema involving the foot and distal third of the leg...
November 24, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29169382/confirmed-ceylon-krait-bungarus-ceylonicus-envenoming-in-sri-lanka-resulting-in-neuromuscular-paralysis-a-case-report
#11
Chamara Dalugama, Indika Bandara Gawarammana
BACKGROUND: Ceylon krait (Bungarus ceylonicus) is a venomous elapid snake endemic to Sri Lanka. It inhabits shaded home gardens and forests in the wet zone of Sri Lanka and might creep into houses in the night. Despite frequent encounters with humans, reports of envenoming are very rare. CASE PRESENTATION: We report a case of a 26-year-old Sri Lankan Sinhalese man with confirmed Ceylon krait envenoming presenting with bilateral partial ptosis, ophthalmoplegia, facial muscle weakness, and dysphagia...
November 24, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29151420/-clinical-application-of-vsd-negative-pressure-aspiration-and-detoxification-in-severe-snake-bite
#12
Zhipeng Zheng, Gonglei Chen, Wei Liang, Xu Ji, Jing Yin, Meiling Liu, Wentao Chen, Yigang Yu, Wei Chen
OBJECTIVE: To assess the clinical efficacy of vacuum sealing drainage (VSD) in the treatment of mixed poisonous snake bite. METHODS: A prospective study was conducted. Forty-three snake bite patients by mixed poisonous snakes admitted to Department of Emergency of the 175th Hospital of People's Liberation Army from February 2015 to February 2017 were enrolled. All patients were divided into routine treatment group (n = 20) and VSD treatment group (n = 23) according to whether early incision decompression and using the VSD technique...
November 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29149409/translationally-controlled-tumor-protein-tctp-hrf-in-animal-venoms
#13
Andrea Senff-Ribeiro
Proteins from TCTP/HRF family were identified as venom toxins of spiders from different genus. We have found a TCTP toxin in the venom gland of Loxosceles intermedia, a venomous spider very common in South Brazil. TCTP from L. intermedia, named LiTCTP, was cloned, produced in a heterologous prokaryotic system, and the recombinant toxin was biochemically characterized. Our results point that LiTCTP is involved in the inflammatory events of Loxocelism, the clinical signs triggered after Loxosceles sp. bite, which include intense inflammatory reaction at the bite site followed by local necrosis...
2017: Results and Problems in Cell Differentiation
https://www.readbyqxmd.com/read/29138410/pla2-like-proteins-myotoxic-mechanism-a-dynamic-model-description
#14
Rafael J Borges, Ney Lemke, Marcos R M Fontes
Phospholipase A2-like (PLA2-like) proteins contribute to the development of muscle necrosis in Viperidae snake bites and are not efficiently neutralized by current antivenom treatments. The toxic mechanisms of PLA2-like proteins are devoid of catalytic activity and not yet fully understood, although structural and functional experiments suggest a dimeric assembly and that the C-terminal residues are essential to myotoxicity. Herein, we characterized the functional mechanism of bothropic PLA2-like structures related to global and local measurements using the available models in the Protein Data Bank and normal mode molecular dynamics (NM-MD)...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29133665/a-rare-case-of-bilateral-tractional-retinal-detachment-following-snakebite
#15
Nicey Roy Thomas, Debmalya Das, Kumar Saurabh, Rupak Roy
A 13-year-old female presented with diminution of vision in both eyes for 3 months following snakebite. Best-corrected visual acuities were hand movement in both eyes. Fundoscopy showed vitreous hemorrhage, and B-scan ultrasonography revealed an underlying tractional retinal detachment (TRD) involving the macula in both eyes. Patient underwent 25-gauge pars plana vitrectomy in conjunction with belt buckling, endolaser, and silicone oil tamponade in the left eye. At 6 weeks postoperatively, best-corrected visual acuity of the left eye was noted to be 20/200 with settled TRD and attached retina...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29124975/ulnar-artery-pseudoaneurysm-and-compartment-syndrome-formation-after-snake-bite-to-the-left-forearm
#16
Lan Pin, Xie Lutao, Fang Weijun, Pan Feng, Chen Chaohui, Wu Jianrong
OBJECTIVE: To report the outcome of a patient who developed pseudoaneurysms and compartment syndrome after a Deinagkistrodon acutus snakebite. CASE REPORT: A 61-year-old man, bitten by Deinagkistrodon acutus in his left forearm, came to the hospital eight hours after the bite. Despite the use of antivenom and supportive therapy, the patient developed compartment syndrome of the left forearm, the tissue pressure was elevated and fasciotomy was arranged. During the initial surgery, part of the necrotic tissues was removed...
November 10, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/29123851/a-lethal-case-of-mamushi-gloydius-blomhoffii-bite-severe-bowel-symptoms-as-a-lethal-sign
#17
Osamu Okamoto, Ryuta Nakashima, Soichiro Yamamoto, Takuzo Hashimoto, Tomomi Takasaki, Hayato Tokuda, Seiichi Sato, Ayako Gamachi, Hiroyuki Hashimoto, Nobuhiro Inagaki
Case: We report a lethal case of a mamushi (Gloydius blomhoffii) bite. An 84-year-old woman was bitten by a mamushi snake on her right elbow. She was initially treated at another hospital, however, because the swelling expanded and her renal function worsened, she was transferred to our hospital. Compartment syndrome, thrombocytopenia, respiratory arrest, and elevated creatinine kinase and lactose dehydrogenase levels were seen; renal failure progressed, and ileus and peritonitis due to colon perforation occurred...
January 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29111117/identification-of-b-cell-recognized-linear-epitopes-in-a-snake-venom-serine-proteinase-from-the-central-american-bushmaster-lachesis-stenophrys
#18
M Madrigal, A Alape-Girón, E Barboza-Arguedas, W Aguilar-Ulloa, M Flores-Díaz
Snake venom serine proteinases are toxins that perturb hemostasis acting on proteins from the blood coagulation cascade, the fibrinolytic or the kallikrein-kinin system. Despite the relevance of these enzymes in envenomations by viper bites, the characterization of the antibody response to these toxins at the molecular level has not been previously addressed. In this work surface-located B cell recognized linear epitopes from a Lachesis stenophrys venom serine proteinase (UniProt accession number Q072L7) were predicted using an artificial neuronal network at the ABCpred server, the corresponding peptides were synthesized and their immunoreactivity was analyzed against a panel of experimental and therapeutic antivenoms...
October 27, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29105506/genome-based-analysis-of-virulence-determinants-of-a-serratia-marcescens-strain-from-soft-tissues-following-a-snake-bite
#19
Yao-Ting Huang, Jan-Fang Cheng, Yi-Ting Liu, Yan-Chiao Mao, Meng-San Wu, Po-Yu Liu
AIM: Serratia marcescens wound infection after snakebite is often associated with aggressive presentations. However, the virulence determinants remain understudied. MATERIALS & METHODS: Whole-genome sequencing was performed on S. marcescens VGH107, an isolate from wound infection secondary to Trimeresurus mucrosquamatus bite. Comparative genomics approach coupled with multivirulent-locus sequencing typing was applied to systematically predict potential virulence factors...
November 6, 2017: Future Microbiology
https://www.readbyqxmd.com/read/29102099/white-lipped-tree-viper-cryptelytrops-albolabris-envenomation-in-an-american-viper-keeper
#20
Spencer Greene, Laura Ann Galdamez, Richard Tomasheski
BACKGROUND: Snakebites are common in many regions of the United States. Bites from exotic species, however, are rare. The white-lipped tree viper, Cryptelytrops (formerly Trimeresurus) albolabris, is a pit viper native to Southeast Asia. Bites are common in countries such as Myanmar, India, Thailand, Indonesia, and China. In this report, we describe an envenomation in an American viper keeper. CASE REPORT: A healthy 28-year-old right-handed man who collects venomous snakes experienced a bite to the distal left thumb from a neonatal C...
October 25, 2017: Journal of Emergency Medicine
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