keyword
MENU ▼
Read by QxMD icon Read
search

geneXpert in tuberculous meningitis

keyword
https://www.readbyqxmd.com/read/27798497/recent-advances-in-the-diagnosis-and-management-of-tuberculous-meningitis
#1
Nguyen T H Mai, Guy E Thwaites
PURPOSE OF REVIEW: Tuberculous meningitis is a devastating infection that is hard to diagnose and treat. We have reviewed tuberculous meningitis original research published within the past 18 months, selecting studies which we consider have most advanced knowledge. RECENT FINDINGS: We review advances in diagnostic methods, anti-tuberculosis chemotherapy, and the common complications of tuberculous meningitis. New commercial molecular diagnostic tests, such as GeneXpert MTB/RIF, have an important role in tuberculous meningitis diagnosis, but as with all other available tests, they lack sensitivity and cannot rule out the disease...
October 27, 2016: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/27430924/-experimental-study-of-genexpert-%C3%A2-system-in-the-diagnosis-of-extra-pulmonary-tuberculosis
#2
Z F Chen, H L Lao, X H Li, J Wang, Q Chen, Z X Wang, D C Wang
OBJECTIVE: To explore the application value of GeneXpert MTB/RIF for detection of extra-pulmonary tuberculosis and resistance to rifampin. METHODS: A total of 150 samples were collected, including 33 needle aspirates from lymphoid tuberculosis, 23 needle aspirates from spinal tuberculosis, 49 from tuberculous pleural effusions, 24 from cerebrospinal fluid of tuberculous cephalomeningitis, and 21 urinary sediment samples from renal tuberculosis. Smear microscopy, mycobacterium tuberculosis culture and the MTB/RIF method were used to examine these samples and their positive rates were compared...
July 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/26966284/genexpert-mtb-rif-to-diagnose-tuberculous-meningitis-perhaps-the-first-test-but-not-the-last
#3
Nathan C Bahr, Suzaan Marais, Maxine Caws, Reinout van Crevel, Robert J Wilkinson, Jaya S Tyagi, Guy E Thwaites, David R Boulware
Tuberculous meningitis (TBM) is the most severe form of tuberculous with substantial mortality. In May 2015, 54 researchers from 10 countries met in Da Lat, Vietnam, to discuss advances in TBM. Among the attendees were researchers involved in pivotal studies on the use of Xpert MTB/Rif for TBM diagnosis. Attendees discussed the 2014 World Health Organization strong recommendation favoring the use of Xpert "in preference to conventional microscopy and culture as the initial diagnostic test for cerebrospinal fluid (CSF) if the sample volume is low or if additional specimens cannot be obtained to make a quick diagnosis...
May 1, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/26071438/genexpert-mtb-rif-assay-as-initial-test-for-diagnosis-of-tuberculous-meningitis
#4
Poojan Shrestha, Buddhi Paudyal, Buddha Basnyat
Tuberculous meningitis (TBM) remains the most dangerous form of tuberculosis with high mortality and potential complications. The prompt diagnosis and treatment of this condition remains a key for better prognosis. A 39-year-old woman presented with severe headache, fever, nausea and vomiting, with a history of headache for a month. On examination, confusion, neck rigidity, ptosis and upward plantar reflexes were present. After 7 days of empiric treatment without resolution of her symptoms, she had another spinal tap performed...
June 12, 2015: BMJ Case Reports
https://www.readbyqxmd.com/read/24197880/evaluation-of-genexpert-mtb-rif-for-diagnosis-of-tuberculous-meningitis
#5
COMPARATIVE STUDY
Nguyen Thi Quynh Nhu, Dorothee Heemskerk, Do Dang Anh Thu, Tran Thi Hong Chau, Nguyen Thi Hoang Mai, Ho Dang Trung Nghia, Pham Phu Loc, Dang Thi Minh Ha, Laura Merson, Tran Thi Van Thinh, Jeremy Day, Nguyen van Vinh Chau, Marcel Wolbers, Jeremy Farrar, Maxine Caws
Tuberculous meningitis (TBM) is the most severe form of tuberculosis. Microbiological confirmation is rare, and treatment is often delayed, increasing mortality and morbidity. The GeneXpert MTB/RIF test was evaluated in a large cohort of patients with suspected tuberculous meningitis. Three hundred seventy-nine patients presenting with suspected tuberculous meningitis to the Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, between 17 April 2011 and 31 December 2012 were included in the study. Cerebrospinal fluid samples were tested by Ziehl-Neelsen smear, mycobacterial growth indicator tube (MGIT) culture, and Xpert MTB/RIF...
January 2014: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/22966426/rapid-diagnosis-of-pulmonary-and-extrapulmonary-tuberculosis-in-hiv-infected-patients-comparison-of-led-fluorescent-microscopy-and-the-genexpert-mtb-rif-assay-in-a-district-hospital-in-india
#6
Gerardo Alvarez-Uria, Jose M Azcona, Manoranjan Midde, Praveen K Naik, Srinivasulu Reddy, Raghuprakash Reddy
HIV-related tuberculosis is difficult to diagnose and is associated with high morbidity and mortality. Recently, the World Health Organization has endorsed the GeneXpert MTB/RIF (Xpert) assay for the diagnosis of pulmonary tuberculosis in HIV-infected patients from developing countries, but information about the use of Xpert for the diagnosis of extrapulmonary tuberculosis is scarce. In this study, we compared the performance of light-emitting diode (LED) auramine fluorescent microscopy and the Xpert assay for the diagnosis of tuberculosis in HIV infected patients in a district hospital of India...
2012: Tuberculosis Research and Treatment
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"