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Multiple Sclerosis exercise

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https://www.readbyqxmd.com/read/27919502/motor-fatigability-after-low-intensity-hand-grip-exercises-in-persons-with-multiple-sclerosis
#1
Deborah Severijns, Mieke Lemmens, Ronald Thoelen, Peter Feys
INTRODUCTION: During maximal, sustained contractions, persons with multiple sclerosis (PwMS) show higher motor fatigability in comparison with healthy persons. It is not known if motor fatigability is also different between PwMS and healthy persons during low-intensity exercises. Thus, the aim of this study was to determine the difference in hand grip fatigability between healthy persons and PwMS for both hands during low-intensity hand grip exercises. METHODS: 19 PwMS and 19 healthy controls performed 18min of hand grip exercises at a maximum of 25% of the maximal voluntary strength, with an electronic hand dynamometer...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27919494/physical-activity-in-pediatric-onset-multiple-sclerosis-validating-a-questionnaire-for-clinical-practice-and-research
#2
Dominique Kinnett-Hopkins, Stephanie A Grover, E Ann Yeh, Robert W Motl
BACKGROUND: Knowledge regarding physical activity (PA) and its benefits in pediatric onset multiple sclerosis (POMS) is growing and suggests high levels of inactivity. The utility of a validated screening tool for clinical settings is unknown. This study evaluated the Godin Leisure-Time Exercise Questionnaire (GLTEQ) as a measure of PA in POMS. METHODS: POMS patients (n=27) and healthy controls (n=45) wore an accelerometer over a 7-day period and then completed the GLTEQ...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27916699/results-of-a-feasibility-randomised-controlled-study-of-the-guidelines-for-exercise-in-multiple-sclerosis-project
#3
Yvonne C Learmonth, Brynn C Adamson, Dominique Kinnett-Hopkins, Maria Bohri, Robert W Motl
There is increasing recognition that exercise is an efficacious strategy for managing many consequences of multiple sclerosis (MS), yet persons with MS are not engaging in sufficient exercise for accruing health benefits. Poor exercise uptake might be associated with the design of previous research. We conducted a randomised controlled trial (RCT) for examining the feasibility of a 4-month home-based, exercise-training program designed based on recent physical activity guidelines for MS and supplemented by behavioural strategies for compliance...
December 1, 2016: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/27911284/different-types-of-exercise-in-multiple-sclerosis-aerobic-exercise-or-pilates-a-single-blind-clinical-study
#4
Bilge Kara, Fadime Küçük, Esra Coşkuner Poyraz, Melda Soysal Tomruk, Egemen İdıman
BACKROUND: The aim of our study is to examine effects of aerobic and Pilates exercises on disability, cognition, physical performance, balance, depression and fatigue in relapsing-remitting Multiple Sclerosis (MS) patients as compared to healthy controls. METHODS: The subjects were divided as aerobic exercise (n = 26), Pilates (n = 9), and the healthy control group (n = 21). We used MSFC, physical performance, Berg balance scale, Beck depression scale, fatique impact scale...
November 25, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27904656/the-berlin-treatment-algorithm-recommendations-for-tailored-innovative-therapeutic-strategies-for-multiple-sclerosis-related-fatigue
#5
REVIEW
Christian Veauthier, Helge Hasselmann, Stefan M Gold, Friedemann Paul
More than 80% of multiple sclerosis (MS) patients suffer from fatigue. Despite this, there are few therapeutic options and evidence-based pharmacological treatments are lacking. The associated societal burden is substantial (MS fatigue is a major reason for part-time employment or early retirement), and at least one out of four MS patients view fatigue as the most burdensome symptom of their disease. The mechanisms underlying MS-related fatigue are poorly understood, and objective criteria for distinguishing and evaluating levels of fatigue and tiredness have not yet been developed...
2016: EPMA Journal
https://www.readbyqxmd.com/read/27895592/effects-of-six-months-training-on-physical-capacity-and-metaboreflex-activity-in-patients-with-multiple-sclerosis
#6
Sara Magnani, Sergio Olla, Massimiliano Pau, Girolamo Palazzolo, Filippo Tocco, Azzurra Doneddu, Maura Marcelli, Andrea Loi, Federica Corona, Francesco Corona, Giancarlo Coghe, Maria G Marrosu, Alberto Concu, Eleonora Cocco, Elisabetta Marongiu, Antonio Crisafulli
Patients with multiple sclerosis (MS) have an increased systemic vascular resistance (SVR) response during the metaboreflex. It has been hypothesized that this is the consequence of a sedentary lifestyle secondary to MS. The purpose of this study was to discover whether a 6-month training program could reverse this hemodynamic dysregulation. Patients were randomly assigned to one of the following two groups: the intervention group (MSIT, n = 11), who followed an adapted training program; and the control group (MSCTL, n = 10), who continued with their sedentary lifestyle...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27889837/exercise-training-effects-on-memory-and-hippocampal-viscoelasticity-in-multiple-sclerosis-a-novel-application-of-magnetic-resonance-elastography
#7
Brian M Sandroff, Curtis L Johnson, Robert W Motl
INTRODUCTION: Cognitive impairment is common and debilitating among persons with multiple sclerosis (MS) and might be managed with exercise training. However, the effects of exercise training on viscoelastic brain properties in this population are unknown. The present pilot study adopted a single-blind randomized controlled trial (RCT) design and is the first to examine the effect of an aerobic exercise training intervention on learning and memory and hippocampal viscoelasticity using magnetic resonance elastography (MRE) in persons with MS...
November 26, 2016: Neuroradiology
https://www.readbyqxmd.com/read/27834736/coduse-group-exercise-programme-improves-balance-and-reduces-falls-in-people-with-multiple-sclerosis-a-multi-centre-randomized-controlled-pilot-study
#8
Anna Carling, Anette Forsberg, Martin Gunnarsson, Ylva Nilsagård
BACKGROUND: Imbalance leading to falls is common in people with multiple sclerosis (PwMS). OBJECTIVE: To evaluate the effects of a balance group exercise programme (CoDuSe) on balance and walking in PwMS (Expanded Disability Status Scale, 4.0-7.5). METHODS: A multi-centre, randomized, controlled single-blinded pilot study with random allocation to early or late start of exercise, with the latter group serving as control group for the physical function measures...
November 10, 2016: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/27803637/exercise-training-in-progressive-multiple-sclerosis-a-comparison-of-recumbent-stepping-and-body-weight-supported-treadmill-training
#9
Lara A Pilutti, John E Paulseth, Carin Dove, Shucui Jiang, Michel P Rathbone, Audrey L Hicks
Background: There is evidence of the benefits of exercise training in multiple sclerosis (MS); however, few studies have been conducted in individuals with progressive MS and severe mobility impairment. A potential exercise rehabilitation approach is total-body recumbent stepper training (TBRST). We evaluated the safety and participant-reported experience of TBRST in people with progressive MS and compared the efficacy of TBRST with that of body weight-supported treadmill training (BWSTT) on outcomes of function, fatigue, and health-related quality of life (HRQOL)...
September 2016: International Journal of MS Care
https://www.readbyqxmd.com/read/27794631/effects-of-different-exercise-modalities-on-ataxia-in-multiple-sclerosis-patients-a-randomized-controlled-study
#10
Yeliz Salcı, Ayla Fil, Kadriye Armutlu, F Gökçem Yildiz, Aslı Kurne, Songül Aksoy, Gülay Nurlu, Rana Karabudak
PURPOSE: To investigate the effects of different exercise protocols on ataxia in patients with multiple sclerosis (MS). METHOD: A total of 42 MS patients, 17 male and 25 female (Expanded Disability Status Scale (EDSS): 3-5), were enrolled in this randomized controlled study. The patients were divided into three groups: a balance training (BT) group, a lumbar stabilization (LS) group and a task-oriented training (TT) group. All groups received balance training; additionally, the LS group received lumbar stabilization exercises, and the TT group received task-oriented training...
October 29, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27728987/pathophysiology-assessment-and-management-of-multiple-sclerosis-fatigue-an-update
#11
Mariarosa Rottoli, Sara La Gioia, Barbara Frigeni, Valeria Barcella
Fatigue is one of the most common symptoms associated with multiple sclerosis, affecting almost 80% of patients with 55% of them reporting it as one of the worst symptoms experienced, often independently of the level of disability. Areas covered: We review the main pathophysiological hypothesis, fatigue assessment scales, and its management. Expert commentary: Fatigue pathophysiology is complex and is often influenced by other secondary but relevant factors (e.g. psychological disturbances, musculoskeletal problems, sleep disorders and medication side effects) which may vary over time...
October 11, 2016: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/27725121/effects-of-exercise-on-irisin-bdnf-and-il-6-serum-levels-in-patients-with-progressive-multiple-sclerosis
#12
Sven Briken, Sina Cathérine Rosenkranz, Oliver Keminer, Stefan Patra, Gesche Ketels, Christoph Heesen, Rainer Hellweg, Ole Pless, Karl-Heinz Schulz, Stefan M Gold
BACKGROUND: Clinical studies have suggested beneficial effects of exercise on cognitive function in ageing adults and neurodegenerative diseases such as dementia. Recent work indicates the same for progressive multiple sclerosis (MS), an inflammatory and degenerative disease of the central nervous system (CNS). The biological pathways associated with these effects are however not well understood. OBJECTIVE: In this randomized controlled study, we explored serum levels of the myokine Irisin, the neurotrophin brain-derived neurotrophic factor (BDNF) and Interleukin-6 (IL-6) during acute endurance exercise and over the course of a 9-weeks endurance exercise training period in n=42 patients with progressive MS...
October 15, 2016: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/27717498/physical-activity-and-its-correlates-in-youth-with-multiple-sclerosis
#13
Stephanie A Grover, Carolyn P Sawicki, Dominique Kinnett-Hopkins, Marcia Finlayson, Jane E Schneiderman, Brenda Banwell, Christine Till, Robert W Motl, E Ann Yeh
OBJECTIVES: To investigate physical activity levels in youth with multiple sclerosis and monophasic acquired demyelinating syndromes ([mono-ADS], ie, children without relapsing disease) compared with healthy controls and to determine factors that contribute to engagement in physical activity. We hypothesized that greater physical activity goal setting and physical activity self-efficacy would be associated with greater levels of vigorous physical activity in youth with multiple sclerosis...
October 4, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27716336/adaptive-vs-non-adaptive-cognitive-training-by-means-of-a-personalized-app-a-randomized-trial-in-people-with-multiple-sclerosis
#14
Ludovico Pedullà, Giampaolo Brichetto, Andrea Tacchino, Claudio Vassallo, Paola Zaratin, Mario Alberto Battaglia, Laura Bonzano, Marco Bove
BACKGROUND: Cognitive impairment is common in multiple sclerosis (MS), but the definition of the best cognitive rehabilitation tools and features is still an open issue among researchers. The aims of the present study were to evaluate the effectiveness of COGNI-TRAcK (a customized application software delivering personalized working memory-based exercises) on cognitively impaired people with MS and to investigate the effects of an adaptive vs. a non-adaptive cognitive training administered by means of COGNI-TRAcK...
October 4, 2016: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/27706046/internet-supported-physical-exercise-training-for-persons-with-multiple-sclerosis-a-randomised-controlled-study
#15
Alexander Tallner, René Streber, Christian Hentschke, Marc Morgott, Wolfgang Geidl, Mathias Mäurer, Klaus Pfeifer
Physical exercise is effective in improving functional outcomes in persons with multiple sclerosis (pwMS). We evaluated the feasibility and effectiveness of internet-based exercise training (e-training) for pwMS on health-related quality of life (HrQoL). Secondary outcomes were muscle strength, aerobic capacity, lung function, physical activity, and fatigue. This is a randomised, controlled trial with a wait-list control group. Data were collected at baseline, after three and six months, and analysed using a hybrid linear model...
September 30, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27676919/efficacity-of-exercise-training-on-multiple-sclerosis-patients-with-cognitive-impairments
#16
Amandine Chenet, Alexandra Gosseaume, Sandrine Wiertlewski, Brigitte Perrouin-Verbe
OBJECTIVE: Cognitive impairment in multiple sclerosis (MS) is common, present in 40 to 60% of patients, and is under diagnosis. Currently, there is no effective drug and non-pharmacological treatments that are developed. We propose to evaluate the effectiveness of exercise training (ET) on cognitive impairment. MATERIALS/PATIENTS AND METHODS: The study included patients from University Hospital of Nantes with an EDSS of between 3 and 4.5. They followed an exercise therapy program during 8 weeks, in groups, including aerobic physical activity (Nordic walking, gymnastics and exercise of balance) and recreational activities (billiards and boccia)...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676916/is-fatigue-associated-with-cardiorespiratory-endurance-among-patients-suffering-from-multiple-sclerosis
#17
Maxime Valet, Gaëtan Stoquart, Yumiko Glibert, Jean-Claude Hakizimana, Thierry Lejeune
OBJECTIVE: Fatigue is the most common and disabling symptom among patients suffering from multiple sclerosis (MS). From the initial stages of the disease, a physical deconditioning is also observed among these patients. The aim of this study is to assess the cardiorespiratory endurance (i.e. exercise tolerance functions) and self-reported fatigue, as well as their associations, among patients suffering from MS with mild disability (expanded disability status scale≤4). MATERIALS/PATIENTS AND METHODS: 21 patients with MS (15 women; age: 26-64 years, median 46 years; duration of disease: 0...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27671243/systematically-developed-pilot-randomized-controlled-trial-of-exercise-and-cognition-in-persons-with-multiple-sclerosis
#18
Brian M Sandroff, Julia M Balto, Rachel E Klaren, Sarah K Sommer, John DeLuca, Robert W Motl
Cognitive impairment is common and debilitating among persons with multiple sclerosis (MS) and might be managed with exercise training. The present pilot study adopted a single-blind randomized controlled trial (RCT) design and is the first to examine the effect of a systematically developed, progressive treadmill walking exercise training intervention on cognition among fully ambulatory persons with MS. Ten fully ambulatory females with MS were randomly assigned into exercise training intervention or waitlist control conditions...
October 2016: Neurocase
https://www.readbyqxmd.com/read/27648171/a-combined-exercise-model-for-improving-muscle-strength-balance-walking-distance-and-motor-agility-in-multiple-sclerosis-patients-a-randomized-clinical-trial
#19
Bahram Sangelaji, Mohammadreza Kordi, Farzaneh Banihashemi, Seyed Massood Nabavi, Sara Khodadadeh, Maryam Dastoorpoor
BACKGROUND: Multiple sclerosis (MS) is a neurological disease with a variety of signs and symptoms. Exercise therapy has been shown to improve physical functions in MS. However, questions about an optimal exercise therapy remain. In this regard, we suggest a combined exercise therapy including aerobic and resistance exercises for MS patients. The study is designed to observe, test and compare the effects of proposed combined exercises on strength, balance, agility, fatigue, speed, and walking distance in people with mild to moderate MS [0 < expanded disability status scale (EDSS) < 5]...
July 6, 2016: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/27580906/fatigue-and-depression-in-multiple-sclerosis-pharmacological-and-non-pharmacological-interventions
#20
REVIEW
P Brenner, F Piehl
Multiple sclerosis (MS) is a neuroinflammatory condition with a prominent progressive neurodegenerative facet that typically affects young- or middle-aged adults. Although physical disabilities have been in the foreground by being easier to assess, there is an increasing interest in mental disabilities and psychiatric co-morbidities, which have a disproportionally high impact on important outcome measures such as quality of life and occupational disability. In particular, cognitive impairment, depression and mental fatigue, which mutually interact with each other, seem to be of importance in this context...
September 2016: Acta Neurologica Scandinavica
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