Read by QxMD icon Read

Multiple Sclerosis exercise

Mariarosa Rottoli, Sara La Gioia, Barbara Frigeni, Valeria Barcella
Fatigue is one of the most common symptoms associated with multiple sclerosis, affecting almost 80% of patients with 55% of them reporting it as one of the worst symptoms experienced, often independently of the level of disability. Areas covered: We review the main pathophysiological hypothesis, fatigue assessment scales, and its management. Expert commentary: Fatigue pathophysiology is complex and is often influenced by other secondary but relevant factors (e.g. psychological disturbances, musculoskeletal problems, sleep disorders and medication side effects) which may vary over time...
October 11, 2016: Expert Review of Neurotherapeutics
Sven Briken, Sina Cathérine Rosenkranz, Oliver Keminer, Stefan Patra, Gesche Ketels, Christoph Heesen, Rainer Hellweg, Ole Pless, Karl-Heinz Schulz, Stefan M Gold
BACKGROUND: Clinical studies have suggested beneficial effects of exercise on cognitive function in ageing adults and neurodegenerative diseases such as dementia. Recent work indicates the same for progressive multiple sclerosis (MS), an inflammatory and degenerative disease of the central nervous system (CNS). The biological pathways associated with these effects are however not well understood. OBJECTIVE: In this randomized controlled study, we explored serum levels of the myokine Irisin, the neurotrophin brain-derived neurotrophic factor (BDNF) and Interleukin-6 (IL-6) during acute endurance exercise and over the course of a 9-weeks endurance exercise training period in n=42 patients with progressive MS...
October 15, 2016: Journal of Neuroimmunology
Stephanie A Grover, Carolyn P Sawicki, Dominique Kinnett-Hopkins, Marcia Finlayson, Jane E Schneiderman, Brenda Banwell, Christine Till, Robert W Motl, E Ann Yeh
OBJECTIVES: To investigate physical activity levels in youth with multiple sclerosis and monophasic acquired demyelinating syndromes ([mono-ADS], ie, children without relapsing disease) compared with healthy controls and to determine factors that contribute to engagement in physical activity. We hypothesized that greater physical activity goal setting and physical activity self-efficacy would be associated with greater levels of vigorous physical activity in youth with multiple sclerosis...
October 4, 2016: Journal of Pediatrics
Ludovico Pedullà, Giampaolo Brichetto, Andrea Tacchino, Claudio Vassallo, Paola Zaratin, Mario Alberto Battaglia, Laura Bonzano, Marco Bove
BACKGROUND: Cognitive impairment is common in multiple sclerosis (MS), but the definition of the best cognitive rehabilitation tools and features is still an open issue among researchers. The aims of the present study were to evaluate the effectiveness of COGNI-TRAcK (a customized application software delivering personalized working memory-based exercises) on cognitively impaired people with MS and to investigate the effects of an adaptive vs. a non-adaptive cognitive training administered by means of COGNI-TRAcK...
October 4, 2016: Journal of Neuroengineering and Rehabilitation
Alexander Tallner, René Streber, Christian Hentschke, Marc Morgott, Wolfgang Geidl, Mathias Mäurer, Klaus Pfeifer
Physical exercise is effective in improving functional outcomes in persons with multiple sclerosis (pwMS). We evaluated the feasibility and effectiveness of internet-based exercise training (e-training) for pwMS on health-related quality of life (HrQoL). Secondary outcomes were muscle strength, aerobic capacity, lung function, physical activity, and fatigue. This is a randomised, controlled trial with a wait-list control group. Data were collected at baseline, after three and six months, and analysed using a hybrid linear model...
September 30, 2016: International Journal of Molecular Sciences
Amandine Chenet, Alexandra Gosseaume, Sandrine Wiertlewski, Brigitte Perrouin-Verbe
OBJECTIVE: Cognitive impairment in multiple sclerosis (MS) is common, present in 40 to 60% of patients, and is under diagnosis. Currently, there is no effective drug and non-pharmacological treatments that are developed. We propose to evaluate the effectiveness of exercise training (ET) on cognitive impairment. MATERIALS/PATIENTS AND METHODS: The study included patients from University Hospital of Nantes with an EDSS of between 3 and 4.5. They followed an exercise therapy program during 8 weeks, in groups, including aerobic physical activity (Nordic walking, gymnastics and exercise of balance) and recreational activities (billiards and boccia)...
September 2016: Annals of Physical and Rehabilitation Medicine
Maxime Valet, Gaëtan Stoquart, Yumiko Glibert, Jean-Claude Hakizimana, Thierry Lejeune
OBJECTIVE: Fatigue is the most common and disabling symptom among patients suffering from multiple sclerosis (MS). From the initial stages of the disease, a physical deconditioning is also observed among these patients. The aim of this study is to assess the cardiorespiratory endurance (i.e. exercise tolerance functions) and self-reported fatigue, as well as their associations, among patients suffering from MS with mild disability (expanded disability status scale≤4). MATERIALS/PATIENTS AND METHODS: 21 patients with MS (15 women; age: 26-64 years, median 46 years; duration of disease: 0...
September 2016: Annals of Physical and Rehabilitation Medicine
Brian M Sandroff, Julia M Balto, Rachel E Klaren, Sarah K Sommer, John DeLuca, Robert W Motl
Cognitive impairment is common and debilitating among persons with multiple sclerosis (MS) and might be managed with exercise training. The present pilot study adopted a single-blind randomized controlled trial (RCT) design and is the first to examine the effect of a systematically developed, progressive treadmill walking exercise training intervention on cognition among fully ambulatory persons with MS. Ten fully ambulatory females with MS were randomly assigned into exercise training intervention or waitlist control conditions...
September 27, 2016: Neurocase
Bahram Sangelaji, Mohammadreza Kordi, Farzaneh Banihashemi, Seyed Massood Nabavi, Sara Khodadadeh, Maryam Dastoorpoor
BACKGROUND: Multiple sclerosis (MS) is a neurological disease with a variety of signs and symptoms. Exercise therapy has been shown to improve physical functions in MS. However, questions about an optimal exercise therapy remain. In this regard, we suggest a combined exercise therapy including aerobic and resistance exercises for MS patients. The study is designed to observe, test and compare the effects of proposed combined exercises on strength, balance, agility, fatigue, speed, and walking distance in people with mild to moderate MS [0 < expanded disability status scale (EDSS) < 5]...
July 6, 2016: Iranian Journal of Neurology
P Brenner, F Piehl
Multiple sclerosis (MS) is a neuroinflammatory condition with a prominent progressive neurodegenerative facet that typically affects young- or middle-aged adults. Although physical disabilities have been in the foreground by being easier to assess, there is an increasing interest in mental disabilities and psychiatric co-morbidities, which have a disproportionally high impact on important outcome measures such as quality of life and occupational disability. In particular, cognitive impairment, depression and mental fatigue, which mutually interact with each other, seem to be of importance in this context...
September 2016: Acta Neurologica Scandinavica
George A Jelinek, Alysha M De Livera, Claudia H Marck, Chelsea R Brown, Sandra L Neate, Keryn L Taylor, Tracey J Weiland
OBJECTIVE: Emerging evidence links modifiable lifestyle risk factors to disease progression in multiple sclerosis (MS). We sought further evidence around this hypothesis through detailed analysis of the association with disability of lifestyle behaviours of a large international sample of people with MS. MATERIALS AND METHODS: A total of 2469 people with MS from 57 countries provided self-reported data via cross-sectional online survey on lifestyle (mostly with validated tools) and the primary outcome measure, disability (Patient Determined Disease Steps), categorised from 8 steps into 3 categories, mild, moderate and major disability...
2016: PloS One
June Halper, Diego Centonze, Scott D Newsome, DeRen Huang, Christopher Robertson, Xiaojun You, Guido Sabatella, Vladimir Evilevitch, Leslie Leahy
BACKGROUND: Flu-like symptoms (FLSs) and injection-site reactions (ISRs) have been reported with interferon beta treatments for multiple sclerosis (MS). We sought to obtain consensus on the characteristics/management of FLSs/ISRs in patients with relapsing-remitting MS based on experiences from the randomized, placebo-controlled ADVANCE study of peginterferon beta-1a. METHODS: ADVANCE investigators with a predefined number of enrolled patients were eligible to participate in a consensus-generating exercise using a modified Delphi method...
July 2016: International Journal of MS Care
Sharon Barak, Yeshayahu Hutzler, Gal Dubnov-Raz, Anat Achiron
This review summarizes the existing knowledge regarding the effects and recommendations for physical training (PTr) in patients with multiple sclerosis (MS). In addition, perceived benefits and barriers to PTr in this population are reviewed. One of the primary aims of rehabilitation for patients with MS is to increase their levels of activity and independence. PTr is a central component in the rehabilitation process. Nonetheless, the use of PTr in the rehabilitation of patients with MS has been a controversial issue for years...
June 2016: Harefuah
Ali Hasanpour-Dehkordi, Nahid Jivad, Kamal Solati
INTRODUCTION: Multiple sclerosis (MS) as a chronic disease could affect patients' various domains of life. AIM: This study was conducted to study the effect of yoga on the physiological indices, anxiety and social functioning of patients with MS in southwest, Iran. MATERIALS AND METHODS: In this clinical trial study, 60 MS patients were enrolled according to inclusion criteria and randomly assigned to two groups of 30 each. Prior to and after intervention, the patients' vital signs were measured...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Tiffany Field
This paper is a review of empirical studies, review and meta-analysis publications on yoga from the last few years. The review includes demographics/prevalence of yoga as a practice, bibliometric analyses of the yoga publications and the use of yoga for physical fitness and cognitive function. Most of the studies reviewed here involve yoga effects on psychiatric and medical conditions. These include pregnancy, prenatal and postpartum depression; stress, PTSD, anxiety, and obesity; cardiovascular conditions including hypertension; pain syndromes including arthritis, headaches and low back pain; autoimmune conditions including asthma, type II diabetes and multiple sclerosis; immune conditions including HIV and breast cancer; and aging problems including balance, osteoporosis and Parkinson's...
August 2016: Complementary Therapies in Clinical Practice
Tiffany Field
In this review, massage therapy has been shown to have beneficial effects on varying conditions including prenatal depression, preterm infants, full-term infants, autism, skin conditions, pain syndromes including arthritis and fibromyalgia, hypertension, autoimmune conditions including asthma and multiple sclerosis, immune conditions including HIV and breast cancer and aging problems including Parkinson's and dementia. Although many of the studies have involved comparisons between massage therapy and standard treatment control groups, several have compared different forms of massage (e...
August 2016: Complementary Therapies in Clinical Practice
Thais Massetti, Isabela Lopes Trevizan, Claudia Arab, Francis Meire Favero, Denise Cardoso Ribeiro-Papa, Carlos Bandeira de Mello Monteiro
INTRODUCTION: Multiple sclerosis (MS) is an inflammatory disease in which the insulating cover of nerve cells in the brain and spinal cord are damaged. The methods used for motor rehabilitation of patients with neurological problems require the performance of several rehabilitation exercises. Recently, studies related to the use of video game consoles have proliferated in the field of motor rehabilitation. Virtual reality (VR) has been proposed as a potentially useful tool for motoring assessment and rehabilitation...
July 2016: Multiple Sclerosis and related Disorders
I Castillo-Bueno, D J Ramos-Campo, J A Rubio-Arias
INTRODUCTION: Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system. MS is characterised by nerve demyelination that can alter nerve transmission and lead to such symptoms as fatigue, muscle weakness, and impaired motor function. There are 47 000 people with MS in Spain. Vibration training can be an effective and complementary alternative to traditional exercise to treat patients with MS. The aim of this study was to analyse the effectiveness of vibration training programmes in patients with MS...
July 19, 2016: Neurología: Publicación Oficial de la Sociedad Española de Neurología
Brian M Sandroff, Robert W Motl, Mark R Scudder, John DeLuca
Cognitive dysfunction is highly prevalent, disabling, and poorly-managed in persons with multiple sclerosis (MS). Recent evidence suggests that exercise might have beneficial effects on cognition in this population. The current systematic, evidence-based review examined the existing literature on exercise, physical activity, and physical fitness effects on cognition in MS to accurately describe the current status of the field, offer recommendations for clinicians, and identify study-specific and participant-specific characteristics for providing future direction for ongoing MS research...
September 2016: Neuropsychology Review
Priscila S Souza, Elaine D Gonçalves, Giulia S Pedroso, Hemelin R Farias, Stella C Junqueira, Rodrigo Marcon, Talita Tuon, Maíra Cola, Paulo C L Silveira, Adair R Santos, João B Calixto, Cláudio T Souza, Ricardo A de Pinho, Rafael C Dutra
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) caused by demyelination, immune cell infiltration, and axonal damage. Herein, we sought to investigate the influence of physical exercise on mice experimental autoimmune encephalomyelitis (EAE), a reported MS model. Data show that both strength and endurance training protocols consistently prevented clinical signs of EAE and decreased oxidative stress, an effect which was likely due to improving genomic antioxidant defense-nuclear factor erythroid 2-related factor (Nrf2)/antioxidant response elements (ARE) pathway-in the CNS...
July 22, 2016: Molecular Neurobiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"