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Coronary Revascularization

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https://www.readbyqxmd.com/read/29457560/prophylactic-intra-aortic-balloon-counterpulsation-before-surgical-myocardial-revascularization-in-patients-with-acute-myocardial-infarction
#1
Philippe Grieshaber, Tobias Schneider, Lukas Oster, Coskun Orhan, Peter Roth, Bernd Niemann, Andreas Böning
INTRODUCTION: Prophylactic intra-aortic balloon counterpulsation (pIABC) is recommended for high-risk patients undergoing coronary artery bypass grafting (CABG) surgery. Criteria for high-risk patients benefiting from pIABC are unclear. This study aimed to specifically describe the effect of pIABC on outcomes of patients with acute myocardial infarction (AMI) undergoing CABG. METHODS: In 178 of 484 AMI patients (non-ST-segment elevation myocardial infarction [NSTEMI] or ST-segment elevation myocardial infarction [STEMI] ≤5 days before surgery) without cardiogenic shock who underwent CABG between 2008 and 2013, pIABC was initiated preoperatively...
February 1, 2018: Perfusion
https://www.readbyqxmd.com/read/29455787/cardiovascular-risk-factors-profile-in-patients-with-acute-coronary-syndrome-with-particular-reference-to-left-ventricular-ejection-fraction
#2
Sheeren Khaled, Rajaa Matahen
BACKGROUND: Acute coronary syndrome (ACS) remains a leading cause of death in the United States. Numerous studies have shown that the degree of LV systolic dysfunction is a major if not the most important determinant of long-term outcome in ACS. OBJECTIVES: To identify the most important risk factors and other clinical predictors which might have impact on left ventricular ejection fraction in patients with ACS. RESULTS: The total patients (299) admitted to our center from July, 2015 till December, 2015; with established diagnosis of ACS were classified in to two groups: Group I: 193 patients with impaired LVEF <40% (64...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29455786/examination-of-the-appropriate-timing-of-reperfusion-therapy-for-recent-myocardial-infarction-a-japanese-single-center-retrospective-study
#3
Yukio Mizuguchi, Hiroki Shibutani, Sho Hashimoto, Takeshi Yamada, Norimasa Taniguchi, Shunsuke Nakajima, Tetsuya Hata, Akihiko Takahashi
BACKGROUND: The various guidelines clearly mention the treatment strategies for in patient of acute myocardial infarction (MI) presenting more than 24h from symptom onset (recent myocardial infarction, RMI). However, the appropriate timing of reperfusion for RMI is unclear. METHODS: We retrospectively evaluated 525 consecutive MI patients who underwent percutaneous coronary intervention (PCI) in our hospital between January 2008 and December 2012. RESULTS: Sixty RMI patients were more frequently associated with cardiac complications such as myocardial rupture (3...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29455782/predictors-of-major-adverse-cardiac-events-following-elective-stenting-of-large-coronary-arteries
#4
Hassan Aghajani, Abdolhakim Alkamel, Akbar Shafiee, Arash Jalali, Younes Nozari, Hamidreza Pourhosseini, Seyed Ebrahim Kassaian, Mojtaba Salarifar, Alimohammad Hajizeinali, Alireza Amirzadegan, Mohammad Alidoosti, Farzad Masoudkabir, Ebrahim Nematipour
OBJECTIVE: Diameter of the affected coronary artery is an important predictor of restenosis and need for revascularization. In the present study, we investigated the frequency and potential risk factors for major adverse cardiac events following elective percutaneous coronary intervention (PCI) and stenting of large coronary arteries. METHODS: We reviewed the data of elective candidates of PCI on a large coronary artery who presented to our center. Demographic, clinical, angiographic and follow-up data of the eligible patients were retrieved from our databank...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29455014/cilostazol-improves-wound-healing-in-patients-undergoing-open-bypass-for-ischemic-tissue-loss-a-propensity-score-matching-analysis
#5
Shinsuke Mii, Atsushi Guntani, Eisuke Kawakubo, Kiyoshi Tanaka, Ryoichi Kyuragi
BACKGROUND: Few reports have described the effects of medication on the wound healing of ischemic ulcers after revascularization. This study was conducted to investigate the effects of cilostazol on wound healing in patients who underwent infrainguinal bypass for ischemic tissue loss. METHODS: Two hundred and sixty-three limbs undergoing de novo infrainguinal bypass for tissue loss from January 2004 to December 2015 were divided into two groups based on whether or not cilostazol was administered after surgery...
February 15, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29454724/-silent-diabetes-and-clinical-outcome-after-treatment-with-contemporary-drug-eluting-stents-the-bio-resort-silent-diabetes-study
#6
Clemens von Birgelen, Marlies M Kok, Naveed Sattar, Paolo Zocca, Cees Doelman, Gert D Kant, Marije M Löwik, Liefke C van der Heijden, Hanim Sen, K Gert van Houwelingen, Martin G Stoel, J Hans W Louwerenburg, Marc Hartmann, Frits H A F de Man, Gerard C M Linssen, Carine J M Doggen, Kenneth Tandjung
OBJECTIVES: This study sought to assess the prevalence and clinical impact of silent diabetes and pre-diabetes in "nondiabetic" percutaneous coronary intervention (PCI) all-comers. BACKGROUND: Patients with undetected and thus untreated (silent) diabetes may have higher event risks after PCI with contemporary drug-eluting stents (DES). METHODS: The BIO-RESORT Silent Diabetes study, performed at Thoraxcentrum Twente, is a substudy of the randomized multicenter BIO-RESORT (BIOdegradable Polymer and DuRable Polymer Drug-eluting Stents in an All COmeRs PopulaTion) trial (NCT01674803)...
February 8, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29454531/orbital-atherectomy-for-the-treatment-of-small-2-5mm-severely-calcified-coronary-lesions-orbit-ii-sub-analysis
#7
Michael S Lee, Richard A Shlofmitz, Evan Shlofmitz, Pratyaksh K Srivastava, Jeremy Kong, Cindy Grines, George Revytak, Jeffrey W Chambers
OBJECTIVES: We assessed the safety and efficacy of orbital atherectomy to modify severely calcified coronary plaque prior to stent implantation in patients with small vessel (2.5mm) disease. BACKGROUND: Severe coronary artery calcification increases the risk of adverse clinical events during percutaneous coronary intervention (PCI). Patients who undergo PCI of small vessels have worse clinical outcomes including higher rates of perforation and dissection. The outcomes of orbital atherectomy of small diameter vessels (2...
October 3, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29453887/coronary-artery-disease-in-heart-transplantation-new-concepts-for-an-old-disease
#8
REVIEW
Mandy Langstraat, Kyra J S Musters, Olivier Manintveld, Marco Masetti, Luciano Potena
BACKGROUND: Cardiac allograft vasculopathy (CAV) remains one of the main long-term complications after heart transplantation. We performed a systematic review focused on articles published in the previous 6 years to reappraise the novel evidences supporting risk-factors, pathology, prevention and treatment of CAV. METHODS: We identified a search string for a literature search on PubMed. We excluded articles specifically focused on diagnosis/biomarkers/imaging only or complications of other diseases...
February 17, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29452841/impact-of-age-following-treatment-of-severely-calcified-coronary-lesions-with-the-orbital-atherectomy-system-3-year-follow-up
#9
Michael S Lee, Richard A Shlofmitz, Brad J Martinsen, Sanjum Sethi, Jeffrey W Chambers
OBJECTIVES: We investigated the safety and efficacy of coronary orbital atherectomy to treat severely calcified lesions prior to stenting based upon age. BACKGROUND: The ORBIT II study reported the safety and efficacy with orbital atherectomy in 443 patients with severely calcified lesions. Elderly patients undergoing percutaneous coronary intervention may be at increased risk for major adverse cardiac events (MACE) and death compared with younger patients. METHODS: Patients were stratified according to age (≥75 year old [174/443, 39...
January 31, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29452484/comparison-of-patients-with-multivessel-disease-treated-at-centers-with-and-without-on-site-cardiac-surgery
#10
Eilon Ram, Ilan Goldenberg, Yigal Kassif, Amit Segev, Jakob Lavee, Nir Shlomo, Ehud Raanani
BACKGROUND: The regional needs and consolidation of cardiac surgery services (CSS) result in an increased number of stand-alone interventional cardiology units. We aimed to explore the impact of a heart team on the decision making and outcomes of patients with multivessel coronary artery disease referred for coronary revascularization in stand-alone interventional cardiology units. METHODS: This prospective study included 1063 consecutive patients with multivessel disease enrolled between January and April 2013 from all 22 hospitals in Israel that perform coronary angiography and percutaneous coronary intervention (PCI), with or without on-site CSS...
March 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29452307/impact-of-metabolic-syndrome-on-clinical-severity-and-long-term-prognosis-in-patients-with-myocardial-infarction-with-st-segment-elevation
#11
Lovic, Dragan B Djordjevic, Ivan S Tasic, Ivana P Nedeljkovic
AIMS: The aim of this study is to evaluate the impact of metabolic syndrome (MetS) on clinical severity and long term prognosis in patients with myocardial infarction with ST segment elevation (STEMI). METHODS: We examined 507 patients with STEMI who were admitted for primary percutaneous coronary intervention classified according to the presence of MetS using American Heart Association and the National Heart, Lung and Blood Institute definition. After applying these criteria, the patients were categorized in patients with MetS and without MetS...
February 13, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29451667/approach-to-concurrent-coronary-and-carotid-artery-disease-epidemiology-screening-and-treatment
#12
Patrícia Feitosa Frota Dos Reis, Pedro Vieira Linhares, Fábio Grunspun Pitta, Eduardo Gomes Lima
The concomitance between coronary artery disease and carotid artery disease is known and well documented. However, it is a fact that, despite the screening methods for these conditions and the advances in surgical treatment, little has been achieved in terms of reducing the risk of complications in the perioperative period. Publications are scarce, being mostly composed of reports or case series. There is little agreement on the best initial therapeutic approach (myocardial versus carotid revascularization) or the best technique to be used (surgery with or without extracorporeal circulation, hybrid treatments, etc...
November 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29450719/coronary-plaque-characteristics-on-baseline-ct-predict-the-need-for-late-revascularization-in-symptomatic-patients-after-percutaneous-intervention
#13
Mengmeng Yu, Zhigang Lu, Wenbin Li, Meng Wei, Jing Yan, Jiayin Zhang
OBJECTIVES: To assess pre-procedural plaque characteristics as determined by coronary CT angiography (CCTA) and their associations with late revascularization in symptomatic post-procedural patients. METHODS: Symptomatic patients with pre-procedural CCTA were prospectively enrolled and referred for invasive coronary angiography (ICA). Plaque characterization was performed on the basis of baseline CCTA data. Multivariate logistic regression analysis with a stepwise selection method was performed to identify independent predictors of late revascularization...
February 15, 2018: European Radiology
https://www.readbyqxmd.com/read/29449442/design-and-rationale-of-the-ripcord-2-trial-does-routine-pressure-wire-assessment-influence-management-strategy-at-coronary-angiography-for-diagnosis-of-chest-pain-a-randomized-controlled-trial-to-compare-routine-pressure-wire-assessment-with-conventional-angiography
#14
REVIEW
Mostafa Elguindy, Rod Stables, Zoe Nicholas, Ian Kemp, Nick Curzen
BACKGROUND: Investigation of anginal chest pain has traditionally involved either assessment of the coronary anatomy by angiography or noninvasive testing for reversible ischemia. Invasive pressure wire assessment at the time of angiography offers information on both anatomy and physiology. Fractional flow reserve-guided percutaneous coronary intervention is associated with lower resource utilization and improved clinical outcome compared with angiographic guidance alone. However, the value of routine fractional flow reserve of all major coronary vessels at the time of diagnostic angiography has not been established in a randomized trial despite persuasive observational data...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29449325/quantitative-flow-ratio-identifies-nonculprit-coronary-lesions-requiring-revascularization-in-patients-with-st-segment-elevation-myocardial-infarction-and-multivessel-disease
#15
Giosafat Spitaleri, Matteo Tebaldi, Simone Biscaglia, Jelmer Westra, Salvatore Brugaletta, Andrea Erriquez, Giulia Passarini, Alessandro Brieda, Antonio Maria Leone, Andrea Picchi, Alfonso Ielasi, Domenico Di Girolamo, Carlo Trani, Roberto Ferrari, Johan H C Reiber, Marco Valgimigli, Manel Sabatè, Gianluca Campo
BACKGROUND: The nonculprit lesion (NCL) management in ST-segment-elevation myocardial infarction patients with multivessel disease is debated. We sought to assess whether quantitative flow ratio (QFR), a noninvasive tool to identify potentially flow-limiting lesions, may be reliable in this scenario. METHODS AND RESULTS: The present proof-of-concept study is based on a 3-step process: (1) identification of the QFR reproducibility in NCLs assessment (cohort A, n=31); (2) prospective validation of QFR diagnostic accuracy in respect to fractional flow reserve (cohort B, n=45); and (3) investigation of long-term clinical outcomes of NCLs stratified according to QFR (cohort C, n=110)...
February 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29449274/clinical-relevance-of-functionally-insignificant-moderate-coronary-artery-stenosis-assessed-by-3-vessel-fractional-flow-reserve-measurement
#16
Jonghanne Park, Joo Myung Lee, Bon-Kwon Koo, Eun-Seok Shin, Chang-Wook Nam, Joon-Hyung Doh, Doyeon Hwang, Jinlong Zhang, Xinyang Hu, JianAn Wang, Fei Ye, Shaoliang Chen, Junqing Yang, Jiyan Chen, Nobuhiro Tanaka, Hiroyoshi Yokoi, Hitoshi Matsuo, Hiroaki Takashima, Yasutsugu Shiono, Takashi Akasaka
BACKGROUND: Understanding of the risk conferred by functionally insignificant lesions in multiple coronary vessels is limited. We investigated the prognostic implications of coronary artery disease (CAD) based on 3-vessel fractional flow reserve (FFR). METHODS AND RESULTS: A total of 1,136 patients underwent FFR measurement in the 3 major epicardial arteries. We defined vessels with "Moderate CAD" as vessels with FFR, 0.81 to 0.87. Patients were classified into Group 1: No apparent CAD (FFR>0...
February 15, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29449272/differential-clinical-outcomes-between-angiographic-complete-versus-incomplete-coronary-revascularization-according-to-the-presence-of-chronic-kidney-disease-in-the-drug-eluting-stent-era
#17
Jihoon Kim, Joo Myung Lee, Ki Hong Choi, Tae-Min Rhee, Doyeon Hwang, Jonghanne Park, Chul Ahn, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Jin-Ho Choi, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon
BACKGROUND: There are limited data regarding the prognostic impact of angiographic complete revascularization (CR) in patients with chronic kidney disease (CKD). We sought to investigate the differential prognostic impact of angiographic CR over incomplete revascularization (IR), according to the presence of CKD in the drug-eluting stent era. METHODS AND RESULTS: Between 2003 and 2011 at Samsung Medical Center, consecutive patients with multivessel disease were stratified by the presence of CKD (estimated glomerular filtration rate <60 mL/min per 1...
February 15, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29447782/comparison-of-drug-eluting-stents-and-drug-coated-balloon-for-the-treatment-of-drug-eluting-coronary-stent-restenosis-a-randomized-restore-trial
#18
Yiu Tung Anthony Wong, Do-Yoon Kang, Jin Bae Lee, Seung-Woon Rha, Young Joon Hong, Eun-Seok Shin, Sung-Ho Her, Chang Wook Nam, Woo-Young Chung, Moo Hyun Kim, Cheol Hyun Lee, Pil Hyung Lee, Jung-Min Ahn, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Duk-Woo Park, Seung-Jung Park
BACKGROUND: This study sought to evaluate the optimal treatment for in-stent restenosis (ISR) of drug-eluting stents (DESs). METHODS: This is a prospective, multicenter, open-label, randomized study comparing the use of drug-eluting balloon (DEB) versus second-generation everolimus-eluting stent for the treatment of DES ISR. The primary end point was in-segment late loss at 9-month routine angiographic follow-up. RESULTS: A total of 172 patients were enrolled, and 74 (43...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447780/nonprimary-pci-at-hospitals-without-cardiac-surgery-on-site-consistent-outcomes-for-all
#19
Matthew J Czarny, Julie M Miller, Daniel Q Naiman, Chao-Wei Hwang, Rani K Hasan, Cynthia C Lemmon, Thomas Aversano
BACKGROUND: The CPORT-E trial showed the noninferiority of nonprimary percutaneous coronary intervention (PCI) at hospitals without cardiac surgery on-site (SoS) compared with hospitals with SoS for 6-week mortality and 9-month major adverse cardiac events (MACE). However, target vessel revascularization (TVR) was increased at non-SoS hospitals. Therefore, we aimed to determine the consistency of the CPORT-E trial findings across the spectrum of enrolled patients. METHODS: Post hoc subgroup analyses of 6-week mortality and 9-month MACE, defined as the composite of death, Q-wave myocardial infarction, or TVR, were performed...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447774/percutaneous-coronary-intervention-of-lesions-with-in-stent-restenosis-a-report-from-the-adapt-des-study
#20
Björn Redfors, Philippe Généreux, Bernhard Witzenbichler, Akiko Maehara, Giora Weisz, Thomas McAndrew, Roxana Mehran, Ajay J Kirtane, Gregg W Stone
BACKGROUND: There is a paucity of data from large contemporary cohorts of patients with in-stent restenosis (ISR) treated with drug-eluting stents (DESs), and no studies have examined the impact of high platelet reactivity (HPR) on the occurrence of ischemic events after ISR percutaneous coronary intervention (PCI) with DESs. We sought to report outcomes after PCI of ISR lesions and its association with HPR. METHODS: Patients in the prospective, multicenter ADAPT-DES study were stratified according to whether they had ISR versus non-ISR PCI...
March 2018: American Heart Journal
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