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https://www.readbyqxmd.com/read/29446715/update-in-women-s-heart-disease-prevention-and-screening
#1
Sarah Tilstra, Melissa A McNeil
The goal in selecting these recent articles was to help identify literature that may change the clinical practice of women's health for internists. Articles were identified by reviewing the high-impact medical and women's health journals, national guidelines, ACP JournalWise, and NEJM Journal Watch. Cardiovascular (CV) disease remains the leading cause of death in women. The emphasis of this review is on identifying opportunities for CV risk reduction to prevent disease and on early identification of women with preexisting atherosclerotic disease to allow for early initiation of medical treatment...
February 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29445535/clinical-update-on-central-hypersomnias
#2
REVIEW
Laura Pérez-Carbonell, Guy Leschziner
The central hypersomnias encompass a range of conditions causing persisting or intermittent excessive daytime sleepiness (EDS). These conditions therefore present not infrequently in general clinical sleep practice, and remain in the differential for patients presenting with sleepiness. Our understanding of the pathophysiology, diagnosis and management of these conditions has progressed significantly over recent years, and in this article we review this group of disorders, focussing in particular on recent changes in classification and diagnosis, pathophysiological advances, and novel treatment options...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29438650/updated-evidence-based-clinical-practice-guidelines-for-the-diagnosis-and-management-of-melanoma-definitive-excision-margins-for-primary-cutaneous-melanoma
#3
Michael J Sladden, Omgo E Nieweg, Julie Howle, Brendon J Coventry, John F Thompson
Definitive management of primary cutaneous melanoma consists of surgical excision of the melanoma with the aim of curing the patient. The melanoma is widely excised together with a safety margin of surrounding skin and subcutaneous tissue, after the diagnosis and Breslow thickness have been established by histological assessment of the initial excision biopsy specimen. Sentinel lymph node biopsy should be discussed for melanomas ≥ 1 mm thickness (≥ 0.8 mm if other high risk features) in which case lymphoscintigraphy must be performed before wider excision of the primary melanoma site...
February 19, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29436433/updates-in-palliative-care-recent-advancements-in-the-pharmacological-management-of-symptoms
#4
Angela Star, Jason W Boland
Symptom management is an important part of both palliative care and end-of-life care. This article will examine the recent research evidence about drugs commonly used for symptom management in adult patients receiving palliative care. In particular, the management of symptoms where recent palliative care-based evidence has changed recommended practice will be reviewed. This includes: breathlessness, delirium, nausea and vomiting in bowel obstruction, opioid-induced constipation and upper respiratory tract secretions...
February 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29436352/does-changing-newborn-bath-procedure-alter-newborn-temperatures-and-exclusive-breastfeeding
#5
Carol Suchy, Cyndi Morton, Rocky Roy Ramos, Alexandra Ehrgott, Megan Marie Quental, Amanda Burridge, Dana N Rutledge
PURPOSE: This evidence-based practice project evaluated effects of changing timing/character of initial newborn baths on infant temperatures and breastfeeding status. BACKGROUND: The hospital protocol for initial bathing procedures was updated: immersion baths; 12 hours postpartum; family included. METHODS: Staff nurse champions provided staff training. The evaluation included three seven-week periods (2016-2017) and three measures: adherence, temperature stabilization, and exclusive breastfeeding...
January 1, 2018: Neonatal Network: NN
https://www.readbyqxmd.com/read/29434545/an-updated-survey-on-statistical-thresholding-and-sample-size-of-fmri-studies
#6
Andy W K Yeung
Background: Since the early 2010s, the neuroimaging field has paid more attention to the issue of false positives. Several journals have issued guidelines regarding statistical thresholds. Three papers have reported the statistical analysis of the thresholds used in fMRI literature, but they were published at least 3 years ago and surveyed papers published during 2007-2012. This study revisited this topic to evaluate the changes in this field. Methods: The PubMed database was searched to identify the task-based (not resting-state) fMRI papers published in 2017 and record their sample sizes, inferential methods (e...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29424297/use-of-immunotherapy-to-treat-metastatic-breast-cancer
#7
Andrea Nicolini, Vivian Barak, Piermario Biava, Paola Ferrari, Giuseppe Rossi, Angelo Carpi
This article reviews the principal attempts of immune-modulation or immune therapy in metastatic breast cancer. It considers their rationale and reports on results from the relevant key clinical trials. Immune-modulatory or immune-stimulating cytokines used alone or combined with conventional therapies is among the principal approaches of immune manipulation in breast cancer. As this issue was recently reviewed by us, the aim of the current article is to discuss our updated and unpublished data on this topic...
February 9, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29422409/computer-therapy-for-the-anxiety-and-depression-disorders-is-effective-acceptable-and-practical-health-care-an-updated-meta-analysis
#8
REVIEW
G Andrews, A Basu, P Cuijpers, M G Craske, P McEvoy, C L English, J M Newby
BACKGROUND: A 2010 meta-analysis of internet-delivered CBT (iCBT) RCTs argued 'computer therapy for the anxiety and depressive disorders was effective, acceptable and practical health care' without data on effectiveness or practicality in routine practice. METHODS: Databases, reviews and meta-analyses were searched for randomised controlled trials of cCBT or iCBT versus a control group (care as usual, waitlist, information control, psychological placebo, pill placebo, etc...
February 1, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29421641/improving-the-quality-and-content-of-midwives-discussions-with-low-risk-women-about-their-options-for-place-of-birth-co-production-and-evaluation-of-an-intervention-package
#9
Catherine Henshall, Beck Taylor, Laura Goodwin, Albert Farre, Miss Eleanor Jones, Sara Kenyon
OBJECTIVE: Women's planned place of birth is gaining increasing importance in the UK, however evidence suggests that there is variation in the content of community midwives' discussions with low risk women about their place of birth options. The objective of this study was to develop an intervention to improve the quality and content of place of birth discussions between midwives and low-risk women and to evaluate this intervention in practice. DESIGN: The study design comprised of three stages: (1) The first stage included focus groups with midwives to explore the barriers to carrying out place of birth discussions with women...
January 31, 2018: Midwifery
https://www.readbyqxmd.com/read/29420458/advisory-committee-on-immunization-practices-recommended-immunization-schedule-for-children-and-adolescents-aged-18-years-or-younger-united-states-2018
#10
Candice L Robinson, José R Romero, Allison Kempe, Cynthia Pellegrini, Peter Szilagyi
In October 2017, the Advisory Committee on Immunization Practices (ACIP) approved the Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger - United States, 2018. The 2018 child and adolescent immunization schedule summarizes ACIP recommendations, including several changes from the 2017 immunization schedules, in three figures and footnotes to the figures. These documents can be found on the CDC immunization schedule website (https://www.cdc.gov/vaccines/schedules/index.html)...
February 9, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29408216/cervical-cancer-screening-what-s-new-updates-for-the-busy-clinician
#11
REVIEW
Salina Zhang, Megan McNamara, Pelin Batur
In the United States, 12,000 women are diagnosed with cervical cancer each year, even though the screening for this disease is safe and effective. There are 3 types of screening options available: cervical cytology ("Pap" test), Pap/HPV (human papillomavirus) co-test, and HPV (human papillomavirus)-only test. With simplified options such as HPV (human papillomavirus) -only screening, providers who have been reluctant to incorporate cervical cancer screening into their primary care practice may feel more comfortable with offering these services to women...
February 2, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29407290/update-on-causes-of-family-refusal-for-organ-donation-and-the-related-factors-reporting-the-changes-over-6-years
#12
M Mojtabaee, F Ghorbani, M Mohsenzadeh, F S Beigee
INTRODUCTION: After significant improvement of the family consent rate to organ donation (OD) in recent years, owing to an increase in cultural activities and social awareness, a plateau has been reached. This study was performed to detect the causes for this plateau. METHODS: We reviewed exact causes of family refusal after providing a list of failed potential donors from July 2015 to December 2016. The expert coordinators responsible for handling the failed cases chose the cause of refusal from the previously prepared list...
January 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29401076/smarttots-update-regarding-anesthetic-neurotoxicity-in-the-developing-brain
#13
Beverley A Orser, Santhanam Suresh, Alex S Evers
SmartTots (http://smarttots.org/) represents a public-private partnership between the International Anesthesia Research Society and the US Food and Drug Administration. Over the past 7 years, SmartTots has worked in collaboration with various stakeholders to determine whether anesthetic drugs have detrimental effects on the developing brain. SmartTots has funded clinical and preclinical studies, organized meetings, served as a repository of peer-reviewed information, and facilitated the development of consensus-based statements...
February 2, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29393664/the-2018-revision-of-the-isber-best-practices-summary-of-changes-and-the-editorial-team-s-development-process
#14
Lori D Campbell, Jonas J Astrin, Yvonne DeSouza, Judith Giri, Ashokkumar A Patel, Melissa Rawley-Payne, Amanda Rush, Nicole Sieffert
An increased need for specimens of reliable and consistent quality for research purposes requires the development of standardized policies and practices for the collection, handling, storage, retrieval, and distribution of specimens and specimen-related data. Providers of specimen resources should strive to incorporate new technologies and state-of-the-science approaches and thus ensure the availability of fit-for-purpose research specimens. Strategies to achieve quality outcomes and performance improvements often include adherence to established standards and implementation of best practices...
February 2, 2018: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/29390988/effectiveness-of-active-school-transport-interventions-a-systematic-review-and-update
#15
Richard Larouche, George Mammen, David A Rowe, Guy Faulkner
BACKGROUND: Active school transport (AST) is a promising strategy to increase children's physical activity. A systematic review published in 2011 found large heterogeneity in the effectiveness of interventions in increasing AST and highlighted several limitations of previous research. We provide a comprehensive update of that review. METHODS: Replicating the search of the previous review, we screened the PubMed, Web of Science, Cochrane, Sport Discus and National Transportation Library databases for articles published between February 1, 2010 and October 15, 2016...
February 1, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29390932/recent-advances-in-the-management-of-multiple-myeloma-clinical-impact-based-on-resource-stratification-consensus-statement-of-the-asian-myeloma-network-at-the-16th-international-myeloma-workshop
#16
Daryl Tan, Jae Hoon Lee, Wenming Chen, Kazuyuki Shimizu, Jian Hou, Kenshi Suzuki, Weerasak Nawarawong, Shang-Yi Huang, Chor Sang Chim, Kihyun Kim, Lalit Kumar, Pankaj Malhotra, Wee Joo Chng, Brian Durie
Predicated on our improved understanding of the disease biology, we have seen remarkable advances in the management of multiple myeloma over the past few years. Recently approved drugs have radically transformed the treatment paradigm and improved survivals of myeloma patients. The progress has necessitated revision of the diagnostic criteria, risk-stratification and response definition. The huge disparities in economy, healthcare infrastructure and access to novel drugs among different Asian countries will hinder the delivery of optimum myeloma care to patients managed in resource-constrained environments...
February 2, 2018: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/29373417/marijuana-perinatal-and-legal-issues-with-use-during-pregnancy
#17
Cynthia Krening, Keri Hanson
Although still illegal at the federal level, marijuana has been legalized for medical and/or recreational use in 29 states, causing a dynamically changing legal and social landscape. While the legalization of marijuana at the state level provides criminal protection for use by adults, there remain civil legal implications for families brought about by mandated reporting laws. Mandated reporting requirements have not been updated to account for the movement toward legalization, risking overload of community child protection resources...
January 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29365346/interventions-for-increasing-fruit-and-vegetable-consumption-in-children-aged-five-years-and-under
#18
REVIEW
Rebecca K Hodder, Fiona G Stacey, Kate M O'Brien, Rebecca J Wyse, Tara Clinton-McHarg, Flora Tzelepis, Erica L James, Kate M Bartlem, Nicole K Nathan, Rachel Sutherland, Emma Robson, Sze Lin Yoong, Luke Wolfenden
BACKGROUND: Insufficient consumption of fruits and vegetables in childhood increases the risk of future chronic diseases, including cardiovascular disease. OBJECTIVES: To assess the effectiveness, cost effectiveness and associated adverse events of interventions designed to increase the consumption of fruit, vegetables or both amongst children aged five years and under. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, MEDLINE and Embase to identify eligible trials on 25 September 2017...
January 25, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29365341/improving-the-accuracy-of-a-clinical-decision-support-system-for-cervical-cancer-screening-and-surveillance
#19
K E Ravikumar, Kathy L MacLaughlin, Marianne R Scheitel, Maya Kessler, Kavishwar B Wagholikar, Hongfang Liu, Rajeev Chaudhry
BACKGROUND:  Clinical decision support systems (CDSS) for cervical cancer prevention are generally limited to identifying patients who are overdue for their next routine/next screening, and they do not provide recommendations for follow-up of abnormal results. We previously developed a CDSS to automatically provide follow-up recommendations based on the American Society of Colposcopy and Cervical Pathology (ASCCP) guidelines for women with both previously normal and abnormal test results leveraging information available in the electronic medical record (EMR)...
January 2018: Applied Clinical Informatics
https://www.readbyqxmd.com/read/29361376/diagnosis-and-treatment-of-slipped-capital-femoral-epiphysis-recent-trends-to-note
#20
Takuya Otani, Yasuhiko Kawaguchi, Keishi Marumo
Slipped capital femoral epiphysis (SCFE) is not frequently encountered during routine practice and diagnosis and treatment are often delayed. It is important to understand symptoms and imaging features to avoid delayed diagnosis. After the diagnosis is made correct classification of the disease is required. The classification should be based on the physeal stability in order to choose safe and effective treatment. However, surgeons should bear in mind that the assessment is challenging and actual physeal stability is not always consistent with the stability predicted by a clinical classification method...
January 17, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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