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https://www.readbyqxmd.com/read/29351091/circadian-rhythms-disturbances-in-alzheimer-disease-current-concepts-diagnosis-and-management
#1
Ángela Milán-Tomás, Colin M Shapiro
The purpose of this review is to provide an overview of the research regarding circadian rhythms in Alzheimer disease (AD). Furthermore, this paper explores the role of melatonin in the pathogenesis of AD and the limitation of trials addressing circadian rhythms disturbances in the AD population. A literature search using Medline with PubMed and Embase was carried out identifying papers focusing on circadian rhythms in AD. Sleep disorders and especially circadian rhythm disturbances are very common in the elderly population but definitely more pronounced in patients with AD...
January 18, 2018: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/29331872/effect-of-physical-activity-on-cognitive-flexibility-depression-and-rbd-in-healthy-elderly
#2
Stefanie Lerche, Alexandra Gutfreund, Kathrin Brockmann, Markus A Hobert, Isabel Wurster, Ulrike Sünkel, Gerhard W Eschweiler, Florian G Metzger, Walter Maetzler, Daniela Berg
OBJECTIVE: The prevalence of Alzheimer's disease and Parkinson's disease increases with the raising number of elderly, which will be a challenging situation for the healthcare systems and society in the future. There is evidence that there are modifiable risk-factors e.g. physical activity for these diseases. Here, we study the interaction between sports inactivity with prodromal markers for neurodegeneration. PATIENTS AND METHODS: We investigated 667 neurologically healthy individuals cross-sectional and a subgroup longitudinal over six years...
January 9, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29320997/investigating-the-associations-between-productive-housework-activities-sleep-hours-and-self-reported-health-among-elderly-men-and-women-in-western-industrialised-countries
#3
Nicholas Kofi Adjei, Tilman Brand
BACKGROUND: After retirement, elderly men and women allocate more time to housework activities, compared to working-age adults. Nonetheless, sleep constitutes the lengthiest time use activity among the elderly, but there has not been any study on the associations between time spent on housework activities, sleep duration and self-reported health among the older population. This study not only examined individual associations between self-reported health and both housework activities and sleep duration, but it also explored self-reported health by the interaction effect between housework activities and sleep duration separately for men and women...
January 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29320338/healthy-behaviors-and-incidence-of-disability-in-community-dwelling-elderly
#4
Ryo Hotta, Hyuma Makizako, Takehiko Doi, Kota Tsutsumimoto, Sho Nakakubo, Keitaro Makino, Takao Suzuki, Hiroyuki Shimada
OBJECTIVES: In this paper and prospective study, we examine the number of healthy behaviors and the incidence of disability in community-dwelling older adults aged 65 years and older. METHODS: Participants (N = 4483) were residents of Obu, Japan who were asked about regular exercise, smoking status, and sleep duration. Demographic variables, history of disease, physi- cal function, and cognitive function were measured as confounders. Information about disabil- ity was obtained from the Obu City Office...
January 1, 2018: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29315202/the-effects-of-white-noise-on-agitated-behaviors-mental-status-and-activities-of-daily-living-in-older-adults-with-dementia
#5
Li-Wei Lin, Shu-Chuan Weng, Hua-Shan Wu, Lu-Jen Tsai, Ya-Ling Lin, Shu-Hui Yeh
BACKGROUND: The aging of society is a global trend, and care of older adults with dementia is an urgent challenge. As dementia progresses, patients exhibit negative emotions, memory disorders, sleep disorders, and agitated behavior. Agitated behavior is one of the most difficult problems for family caregivers and healthcare providers to handle when caring for older adults with dementia. PURPOSE: The aim of this study was to investigate the effectiveness of white noise in improving agitated behavior, mental status, and activities of daily living in older adults with dementia...
February 2018: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29306907/new-aspects-in-the-pathomechanism-of-diseases-of-civilization-particularly-psychosomatic-disorders-part-2-chronic-hypocapnia-and-hypercapnia-in-the-medical-practice
#6
Andras Sikter, Zoltan Rihmer, Roberto de Guevara
The authors seek to find new connections between recent results of biology and older theories. This paper aims to assemble the jigsaw puzzle. The theoretical background of the hypothesis was described in the previous issue of the journal (Sikter et al. 2017a). Human stress response often coexists with persistent hypocapnia or hypercapnia - developing via psychosomatic pathomechanism - which can lead to mental and psychosomatic illnesses. Chronic hypocapnia mainly generates hyperarousal disorders which may be reversible for an extended time, however, vicious cycles may start when hypoxia and/or severe somatic diseases are simultaneously present (commonly in the elderly), which conditions often end with death without medical help...
September 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29304797/suprapubic-tube-versus-urethral-catheter-drainage-after-robot-assisted-radical-prostatectomy-a-systematic-review-and-meta-analysis
#7
Zhongyu Jian, Shijian Feng, Yuntian Chen, Xin Wei, Deyi Luo, Hong Li, Kunjie Wang
BACKGROUND: Prostate cancer is one of the most common cancers in the elderly population. The standard treatment is radical prostatectomy (RARP). However, urologists do not have consents on the postoperative urine drainage management (suprapubic tube (ST)/ urethral catheter (UC)). Thus, we try to compare ST drainage to UC drainage after robot-assisted radical prostatectomy regarding to comfort, recovery rate and continence using the method of meta-analysis. METHODS: A systematic search was performed in Dec...
January 5, 2018: BMC Urology
https://www.readbyqxmd.com/read/29298664/the-prevention-of-delirium-in-elderly-with-obstructive-sleep-apnea-podesa-study-protocol-for-a-multi-centre-prospective-randomized-controlled-trial
#8
Jean Wong, David Lam, Stephen Choi, Mandeep Singh, Naveed Siddiqui, Sanjeev Sockalingam, Frances Chung
BACKGROUND: Delirium is a common problem that occurs in 5-50% of elderly individuals following surgery. Patients who develop delirium after surgery are at increased risk for serious complications. Recent studies suggest that patients with obstructive sleep apnea (OSA), a sleep disorder characterized by repeated episodes of complete or partial blockage of the upper airway - are at greater risk to develop delirium. OSA is more common in elderly individuals but is often undiagnosed. Identification and treatment of unrecognized OSA may reduce the incidence of postoperative delirium...
January 3, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29297596/neuropathology-of-autonomic-dysfunction-in-synucleinopathies
#9
REVIEW
Elizabeth A Coon, Jeremy K Cutsforth-Gregory, Eduardo E Benarroch
The synucleinopathies-Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and pure autonomic failure-result from distinct patterns of abnormal α-synuclein aggregation throughout the nervous system. Autonomic dysfunction in these disorders results from variable involvement of the central and peripheral autonomic networks. The major pathologic hallmark of Parkinson's disease and dementia with Lewy bodies is Lewy bodies and Lewy neurites; of multiple system atrophy, oligodendroglial cytoplasmic inclusions; and of pure autonomic failure, peripheral neuronal cytoplasmic inclusions...
January 3, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29283931/resistance-exercise-training-is-more-effective-than-interval-aerobic-training-in-reducing-blood-pressure-during-sleep-in-hypertensive-elderly-patients
#10
Rodrigo F Bertani, Giulliard O Campos, Diego M Perseguin, José Bonardi, Eduardo Ferriolli, Julio C Moriguti, Nereida K C Lima
An appropriate fall in blood pressure (BP) during sleep is known to be related to a lower cardiovascular risk. The objective of the present study was to compare the effect of different types of training on hypertensive elderly patients under treatment in terms of pressure variability assessed by the nocturnal decline in BP. Hypertensive elderly subjects under pharmacological treatment were randomly assigned to the following groups: 12 weeks of continuous aerobic training (CA), interval aerobic training (IA), resistance training (R), or control (C)...
December 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29235907/a-validation-study-of-fitbit-charge-2%C3%A2-compared-with-polysomnography-in-adults
#11
Massimiliano de Zambotti, Aimee Goldstone, Stephanie Claudatos, Ian M Colrain, Fiona C Baker
We evaluated the performance of a consumer multi-sensory wristband (Fitbit Charge 2™), against polysomnography (PSG) in measuring sleep/wake state and sleep stage composition in healthy adults. In-lab PSG and Fitbit Charge 2™ data were obtained from a single overnight recording at the SRI Human Sleep Research Laboratory in 44 adults (19-61 years; 26 women; 25 Caucasian). Participants were screened to be free from mental and medical conditions. Presence of sleep disorders was evaluated with clinical PSG...
December 13, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29223863/what-can-predict-and-prevent-the-long-term-use-of-benzodiazepines
#12
Takeo Hata, Tetsufumi Kanazawa, Takeshi Hamada, Masami Nishihara, Ashley Ian Bush, Hiroshi Yoneda, Miki Nakajima, Takahiro Katsumata
Although benzodiazepines (BZDs) are commonly prescribed for insomnia or anxiety, long-term use of BZDs causes serious adverse effects such as daytime drowsiness and cognitive decline. In the current study, we evaluated the predictors and preventers of long-term usage of BZDs from a retrospective survey by utilizing the 12-year prescription record of a university hospital. From the prescription data of 92,005 people, users of BZDs (n = 3,470, male = 39.2%, mean age = 60 ± 17.5) were analyzed. During this period, both the number of prescriptions (2722 in 2004 to 1019 in 2016) and the number of BZDs (1...
November 24, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29213524/delirium-in-the-elderly-a-systematic-review-of-pharmacological-and-non-pharmacological-treatments
#13
Cecília Carboni Tardelli Cerveira, Cláudia Cristina Pupo, Sigrid De Sousa Dos Santos, José Eduardo Mourão Santos
Delirium is a common disorder associated with poor prognosis, especially in the elderly. The impact of different treatment approaches for delirium on morbimortality and long-term welfare is not completely understood. OBJECTIVE: To determine the efficacy of pharmacological and non-pharmacological treatments in elderly patients with delirium. METHODS: This systematic review compared pharmacological and non-pharmacological treatments in patients over 60 years old with delirium...
July 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29213496/effects-of-a-cognitive-training-program-and-sleep-hygiene-for-executive-functions-and-sleep-quality-in-healthy-elderly
#14
Katie Moraes de Almondes, Maria Emanuela Matos Leonardo, Ana Maria Souza Moreira
Introduction: The aging process causes changes in the sleep-wake cycle and cognition, especially executive functions. Interventions are required to minimize the impact of the losses caused by the aging process. Objective: To evaluate the effects of a cognitive training program and psychoeducation on sleep hygiene techniques for executive functions and sleep quality in healthy elderly. Methods: The participants were 41 healthy elderly randomized into four groups ([CG] control group, cognitive training group [CTG], sleep hygiene group [SHG] and cognitive training and hygiene group [THG])...
January 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29213208/awareness-of-malaria-and-treatment-seeking-behaviour-among-persons-with-acute-undifferentiated-fever-in-the-endemic-regions-of-myanmar
#15
Phyo Aung Naing, Thae Maung Maung, Jaya Prasad Tripathy, Tin Oo, Khin Thet Wai, Aung Thi
Background: Myanmar has a high burden of malaria with two-third of the population at risk of malaria. One of the basic elements of the Roll Back Malaria Initiative to fight against malaria is early diagnosis and treatment within 24 h of fever. Public awareness about malaria is a key factor in malaria prevention and control and in improving treatment-seeking behaviour. Methods: A large community-based survey was carried out in 27 townships of malaria endemic regions in Myanmar in 2015 which reported on the knowledge, behaviour and practices around malaria in the general population...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29210873/the-effect-of-aromatherapy-on-sleep-quality-of-elderly-people-residing-in-a-nursing-home
#16
Saide Faydalı, Funda Çetinkaya
BACKGROUND: Sleep is important for health and quality of life in the elderly, and sleep disturbances are reported to be associated with many of the adverse medical conditions. PURPOSE: This research was carried out to evaluate the effect of inhalation of lavender oil on sleep quality of nursing home residents. METHODS: A questionnaire was used to evaluate sociodemographic characteristics and sleeping properties of the 30 volunteers, enrolled...
January 2018: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29208334/factors-influencing-recurrent-emergency-department-visits-for-epistaxis-in-the-elderly
#17
Mohamad R Chaaban, Dong Zhang, Vicente Resto, James S Goodwin
OBJECTIVE: Our objective is to determine the risk factors associated with recurrent epistaxis requiring emergency department (ED) visits in the elderly. METHODS: We used a 5% national sample of Medicare data from January 2012 through December 2013. Our cohort included patients with a new diagnosis of epistaxis in the ED, defined as no epistaxis in the prior 12 months. We assessed the rates of ED visits for recurrent epistaxis in the 12 months following the incident visit...
December 2, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29206050/association-between-short-and-long-sleep-durations-and-cardiovascular-outcomes-a-systematic-review-and-meta-analysis
#18
Chayakrit Krittanawong, Anusith Tunhasiriwet, Zhen Wang, HongJu Zhang, Ann M Farrell, Sakkarin Chirapongsathorn, Tao Sun, Takeshi Kitai, Edgar Argulian
BACKGROUND: A shorter sleep duration has been identified as a risk factor for cardiovascular diseases and increased mortality. It has been hypothesized that a short sleep duration may be linked to changes in ghrelin and leptin production, leading to an alteration of stress hormone production. Here, we conducted a systematic review and meta-analysis to investigate the potential relationship between a sleep duration and cardiovascular disease mortality. METHODS: We conducted a comprehensive search of Ovid Medline In-Process and other non-indexed citations, Ovid MEDLINE, Ovid Embase, Ovid Cochrane Central Register of Controlled Trials, and Scopus from database inception to March 2017...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29203963/ingestion-of-green-tea-with-lowered-caffeine-improves-sleep-quality-of-the-elderly-via-suppression-of-stress
#19
Keiko Unno, Shigenori Noda, Yohei Kawasaki, Hiroshi Yamada, Akio Morita, Kazuaki Iguchi, Yoriyuki Nakamura
Epidemiological and animal studies have demonstrated that ingestion of green tea enhances healthy life. However, caffeine in green tea can interfere with sleep. In this report, we examined the effect of green tea with lowered caffeine, low-caffeine green tea, on stress and sleep of the elderly. The participants (n = 10, mean age 89.3 ± 4.2 years) drank five cups/day of standard green tea for 1 week. Subsequently, they drank five cups/day of low-caffeine green tea for 2 weeks. Salivary α-amylase activity (sAA) was measured as a stress marker...
November 2017: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/29201813/risk-factors-and-functional-impact-of-medical-complications-in-stroke
#20
Bo-Ram Kim, Jongmin Lee, Min Kyun Sohn, Deog Young Kim, Sam-Gyu Lee, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, Eun Young Han, Yun-Hee Kim
Objective: To determine the incidence and risk factors for medical complications in Korean patients suffering from stroke and the impact of such complications on post-stroke functional outcomes. Methods: We assessed patients enrolled in a prospective cohort study. All recruited patients had suffered a first acute stroke episode and been admitted to nine university hospitals in Korea between August 2012 and June 2015. We analyzed patient and stroke characteristics, comorbidities, prevalence of post-stroke medical complications, and functional outcomes at time of discharge and 3, 6, and 12 months after stroke onset...
October 2017: Annals of Rehabilitation Medicine
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