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https://www.readbyqxmd.com/read/29779616/sleep-apnea-and-sleep-disordered-breathing
#1
REVIEW
Jiahui Lin, Maria Suurna
Older adults undergo gradual changes in their sleep patterns. It is important to differentiate normal age-related sleep changes from sleep disorders. Because sleep disorders can impact an older adult's day-to-day life and contribute to various comorbidities, these patients should be carefully screened by using a detailed medical history, combined with a detailed sleep history. There is a high prevalence of undiagnosed and untreated sleep apnea in the elderly. Early identification and appropriate management of this disorder may not only provide improvement in quality of life but also decrease disease-associated morbidity and mortality...
May 17, 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29773418/-the-obstructive-sleep-apnoea-syndrome-is-not-only-bad-for-the-heart
#2
J Rajaoarifetra, A Palot, D Tissier Ducamp, C Tummino, M Gouitaa, P Chanez
Obstructive sleep apnoea (OSA) is common in the general population, particularly in the elderly. This syndrome is frequently responsible for severe cardiovascular complications. However, the indications for its treatment in the elderly remain controversial. We report the case of a 79-year-old man with severe, undiagnosed OSA who inhaled his fixed dental bridge during sleep. The inhaled foreign body came to rest in the lumen of the left main stem bronchus. The association of obesity with a body mass index of 30kg/m2 , snoring with breathing pauses reported by his partner, nocturia, morning headache and an Epworth score of 11 led to polysomnography which confirmed OSA with an apnoea/hypopnoea index of 53 per hour...
May 14, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29768372/technologies-for-participatory-medicine-and-health-promotion-in-the-elderly-population
#3
Laura Nieto-Riveiro, Betania Groba, M Carmen Miranda, Patricia Concheiro, Alejandro Pazos, Thais Pousada, Javier Pereira
INTRODUCTION: The progressive aging of the population is a socio-demographic phenomenon experienced by most countries in the world in recent decades, especially in Japan and in many European Union countries. During this process, so-called "geriatric syndromes" frequently occur. The focus of this study is the quality of life of the elderly in relation to these 3 factors: risk of falls, urinary incontinence, and insomnia. OBJECTIVE: The main purpose is to determine the impact of a multifactorial intervention program implemented with institutionalized elderly people...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29768343/potential-common-factors-associated-with-predisposition-to-common-cold-in-middle-aged-and-elderly-japanese-a-community-based-cross-sectional-study
#4
Michi Shibata, Taizo Iwane, Ryoko Higuchi, Kaname Suwa, Kei Nakajima
People worldwide frequently catch a common cold, which occasionally develops into secondary severe conditions such as pneumonia. However, it is unclear whether predisposition to the common cold is associated with the individual's characteristics including age, body weight, lifestyles, diets, and intestinal functions, besides exposure to a responsible pathogen. We addressed this issue epidemiologically considering many relevant clinical factors.We reviewed data from a cross-sectional study consisting of 39,524 apparently healthy Japanese aged 40 to 79 years (26,975 men and 12,549 women) who underwent a checkup in 2007...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29760940/analyses-of-non-benzodiazepine-induced-adverse-events-and-prognosis-in-elderly-patients-based-on-the-japanese-adverse-drug-event-report-database
#5
Yoshihiro Noguchi, Anri Ueno, Hayato Katsuno, Manami Otsubo, Aki Yoshida, Yuta Kanematsu, Ikuto Sugita, Tomoya Tachi, Teruo Tsuchiya, Hitomi Teramachi
Background: The contents of the guidelines for the use of non-benzodiazepines (Z-drugs) differ slightly between THE JAPANESE SOCIETY OF SLEEP RESEARCH and THE JAPAN GERIATRIC SOCIETY, and the recommended directions are conflicting. Therefore, we analyzed the use of the Japanese Adverse Drug Event Report database (JADER) for identifying adverse events (AEs) caused by Z-drugs and clarifying their occurrence trend and prognosis. Methods: The signal value for comparison was calculated by using the proportional reporting ratio (PRR) and chi-squared test (χ2 ) results of data of elderly and non-elderly patients...
2018: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/29760253/deprescribing-benzodiazepine-receptor-agonists-evidence-based-clinical-practice-guideline
#6
Kevin Pottie, Wade Thompson, Simon Davies, Jean Grenier, Cheryl A Sadowski, Vivian Welch, Anne Holbrook, Cynthia Boyd, Robert Swenson, Andy Ma, Barbara Farrell
OBJECTIVE: To develop an evidence-based guideline to help clinicians make decisions about when and how to safely taper and stop benzodiazepine receptor agonists (BZRAs); to focus on the highest level of evidence available and seek input from primary care professionals in the guideline development, review, and endorsement processes. METHODS: The overall team comprised 8 clinicians (1 family physician, 2 psychiatrists, 1 clinical psychologist, 1 clinical pharmacologist, 2 clinical pharmacists, and 1 geriatrician) and a methodologist; members disclosed conflicts of interest...
May 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29750977/high-definition-transcranial-direct-current-stimulation-changes-older-adults-subjective-sleep-and-corresponding-resting-state-functional-connectivity
#7
Jing Sheng, Chao Xie, Dong-Qiong Fan, Xu Lei, Jing Yu
With advanced age, older adults show functional deterioration in sleep. Transcranial direct current stimulation (tDCS), a noninvasive brain stimulation, modulates individuals' behavioral performance in various cognitive domains. However, the modulation effect and neural mechanisms of tDCS on sleep, especially for the elderly population are not clear. Here, we aimed to investigate whether high-definition transcranial direct current stimulation (HD-tDCS) could modulate community-dwelling older adults' subjective sleep and whether these potential improvements are associated with the large-scale brain activity alterations recorded by functional magnetic resonance imaging...
May 8, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29747605/gender-dependent-association-between-sleep-duration-and-overweight-incidence-in-chinese-school-children-a-national-follow-up-study
#8
Muqing Cao, Yanna Zhu, Xiuhong Li, Yajun Chen, Jun Ma, Jin Jing
BACKGROUND: The relationship between sleep duration and overweight risk remains unexplored among Chinese children. This study aims to evaluate this association in a national investigation with school-aged population. METHODS: There were 18,302 normal weight children in this Chinese national study which conducted during 2013-2014 included in the research. Anthropometric measurements were performed both at baseline and after 6-9 month. Sleep duration, physical activity, food intake and social economic information were collected by self-report questionnaire...
May 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29738471/the-association-between-sleep-duration-and-25-hydroxyvitamin-d-concentration-with-obesity-in-an-elderly-korean-population-a-cross-sectional-study
#9
Miae Doo
Studies have recently reported an association between sleep duration and obesity in some individuals. Vitamin D deficiency is common in elderly populations and is also associated with obesity. In this study, the combined interaction effect of vitamin D levels and sleep duration on obesity-related variables was analyzed in 3757 individuals from an elderly Korean population using the Korean National Health and Nutrition Examination Survey. Significant differences were observed in the interaction effect of the vitamin D levels and sleep duration on obesity-related variables, including BMI ( p = 0...
May 8, 2018: Nutrients
https://www.readbyqxmd.com/read/29733807/fractal-regulation-and-incident-alzheimer-s-disease-in-elderly-individuals
#10
Peng Li, Lei Yu, Andrew S P Lim, Aron S Buchman, Frank A J L Scheer, Steven A Shea, Julie A Schneider, David A Bennett, Kun Hu
INTRODUCTION: Healthy physiological systems exhibit fractal regulation (FR), generating similar fluctuation patterns in physiological outputs across different time scales. FR in motor activity is degraded in dementia, and the degradation correlates to cognitive decline. We tested whether degraded FR predicts Alzheimer's disease dementia. METHODS: FR in motor activity was assessed in 1097 nondemented older adults at baseline. Cognition was assessed annually for up to 11 years...
May 4, 2018: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/29724218/potential-effect-of-household-environment-on-prevalence-of-tuberculosis-in-india-evidence-from-the-recent-round-of-a-cross-sectional-survey
#11
S K Singh, Gyan Chandra Kashyap, Parul Puri
BACKGROUND: Tuberculosis (TB) has been a major health problem globally since ages, and even today, it is a major cause of morbidity in millions of people each year. In 2015 alone, TB accounted for about 1.4 million deaths globally, with India carrying the biggest burden of the disease. The physical environment of the household, an individual living in, has a significant influence on the incidence of TB. Thus, an understanding of the socio-economic, demographic and environmental factors that individuals are exposed to is of importance...
May 3, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29724113/impact-of-positive-pressure-treatment-of-the-airway-on-health-related-quality-of-life-in-elderly-patients-with-obstructive-sleep-apnea
#12
Jesús Serrano Merino, Luis Ángel Pérula de Torres, Wayne A Bardwell, Rafaela Muñoz Gómez, Ana Roldán Villalobos, Nuria Feu Collado, Roger Ruiz-Moral, Bernabé Jurado-Gámez
BACKGROUND: Obstructive sleep apnea (OSA) is a chronic illness that increases in prevalence with age. Treatment includes continuous positive airway pressure (CPAP) devices. Studies about the use of CPAP in the elderly are scarce. The main objective of this study is to determine whether CPAP contributes to improvement in health-related quality of life (HRQL) in elderly patients with OSA. METHOD: This was a prospective, pre-/postintervention assessment of a cohort of patients ≥65 years of age with OSA diagnosis by polysomnography who were being treated with CPAP and were physically independent and had good cognitive status...
January 1, 2018: Biological Research for Nursing
https://www.readbyqxmd.com/read/29722881/changes-in-nocturnal-sleep-and-daytime-nap-durations-predict-all-cause-mortality-among-older-adults-the-panel-on-health-and-ageing-of-singaporean-elderly
#13
Grand H-L Cheng, Rahul Malhotra, Truls Østbye, Angelique Chan, Stefan Ma, June C Lo
Study Objectives: To determine the effects of changes in nocturnal sleep and daytime nap durations on all-cause mortality among older adults. Methods: 2448 community-dwelling older Singaporeans (≥60 years) reported their nocturnal sleep and daytime nap durations at baseline (2009) and the 2-year follow-up. At each phase, they were grouped into the recommended (7-8h), short (≤6h), and long (≥9h) sleep duration categories, and the none (0h), short (≤1h), and long (>1h) nap duration categories...
May 2, 2018: Sleep
https://www.readbyqxmd.com/read/29710716/brain-inflammation-connects-cognitive-and-non-cognitive-symptoms-in-alzheimer-s-disease
#14
M Clara Selles, Mauricio M Oliveira, Sergio T Ferreira
Alzheimer's disease (AD) is the main form of dementia in the elderly and affects greater than 47 million people worldwide. Care for AD patients poses very significant personal and economic demands on individuals and society, and the situation is expected to get even more dramatic in the coming decades unless effective treatments are found to halt the progression of the disease. Although AD is most commonly regarded as a disease of the memory, the entire brain is eventually affected by neuronal dysfunction or neurodegeneration, which brings about a host of other behavioral disturbances...
April 25, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29710704/assessment-of-the-mid-life-demographic-and-lifestyle-risk-factors-of-dementia-using-data-from-the-framingham-heart-study-offspring-cohort
#15
Jinlei Li, Matthew Ogrodnik, Vijaya B Kolachalama, Honghuang Lin, Rhoda Au
BACKGROUND: Dementia is the leading cause of dependence and disability in the elderly population worldwide. However, currently there is no effective medication for dementia treatment. Therefore, identifying life-related risk factors including some that are modifiable may provide important strategies for reducing risk of dementia. OBJECTIVE: This study aims to highlight associations between easily obtainable life risk factors in mid-life and dementia in later adulthood...
April 27, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29705780/a-case-of-ventricular-fibrillation-in-a-frail-patient-with-chronic-obstructive-pulmonary-disease-obstructive-sleep-apnea-syndrome-and-electrolytic-disorder
#16
Nicola Marchitto, Monica Mauti, Simona Andreozzi, Alberto Pannozzi, Serenella G Dalmaso, Gianfranco Raimondi
Chronic obstructive pulmonary disease (COPD) is associated with an increased cardiovascular risk, although the pathophysiological mechanisms responsible for this interdependence are not completely known. For instance, the increased sympathetic activity may be implied. The severity of COPD correlates with various arrhythmic manifestations such as atrial fibrillation, atrial flutter, and either sustained or nonsustained ventricular tachycardia. COPD and obstructive sleep apnea syndrome may increase the overall cardiovascular risk, especially in elderly patients...
2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29703506/safety-and-short-term-outcomes-of-laparoscopic-sleeve-gastrectomy-for-patients-over-65-years-old-with-severe-obesity
#17
Panagiotis Lainas, Carmelisa Dammaro, Martin Gaillard, Gianfranco Donatelli, Hadrien Tranchart, Ibrahim Dagher
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is a widely accepted, stand-alone bariatric operation. Data on elderly patients undergoing LSG are scarce. OBJECTIVES: The aim of this study was to demonstrate that LSG is safe and effective for patients>65 years old with severe obesity. SETTING: Department of Minimally Invasive Digestive Surgery, Antoine-Beclere Hospital, AP-HP, Paris-Saclay University, France. METHODS: Prospectively collected data from consecutive patients undergoing LSG were retrospectively analyzed...
March 8, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29696938/analysis-of-osas-incidence-and-influential-factors-in-middle-aged-and-elderly-patients-with-hypertension
#18
Shuang Wang, Xinqing Niu, Peipei Zhang, Dexing Su, Jing Zhang, Wei Liu
BACKGROUND: To investigate the detection rate and influencing factors of obstructive sleep apnea syndrome (OSAS) in middle-aged and elderly patients with hypertension. METHODS: A total of 440 patients with hypertension were selected as the research objects, all of them participated in the Berlin questionnaire survey, and the polysomnography (PSG) was performed on the patients with a high risk of OSAS. The detection rate of OSAS was analyzed, the clinical data between non-OSAS group and OSAS group were compared and stepwise linear regression and Logistic regression were used to analyze the related influencing factors to apnea hyponea index (AHI) and OSAS in hypertensive patients...
April 24, 2018: Minerva Medica
https://www.readbyqxmd.com/read/29692887/analyzing-the-changes-of-health-condition-and-social-capital-of-elderly-people-using-wearable-devices
#19
Siyu Zhou, Atsushi Ogihara, Shoji Nishimura, Qun Jin
Purpose: Rapid developments in information technology have enabled wearable devices to be applied in the health field. In elderly adults, wearable devices aid in data collection and exerts a positive effect on their social capital. This study evaluated the changes in these two parameters among elderly adults using wearable devices, and analyzed the effect of these devices on their daily lives. Methods: We selected 18 elderly people using wearable devices, between February and May 2017...
December 2018: Health Information Science and Systems
https://www.readbyqxmd.com/read/29680809/impact-of-dexmedetomidine-infusion-during-general-anaesthesia-on-incidence-of-postoperative-delirium-in-elderly-patients-after-major-non-cardiac-surgery-study-protocol-of-a-randomised-double-blinded-and-placebo-controlled-trial
#20
Bo-Jie Wang, Chun-Jing Li, Jian Hu, Huai-Jin Li, Chao Guo, Zhen-Han Wang, Qiao-Chu Zhang, Dong-Liang Mu, Dong-Xin Wang
INTRODUCTION: Delirium is a common complication in the elderly after surgery and is associated with worse outcomes. Multiple risk factors are related with postoperative delirium, such as exposure to general anaesthetics, pain and postoperative inflammatory response. Preclinical and clinical studies have shown that dexmedetomidine attenuated neurotoxicity induced by general anaesthetics, improved postoperative analgesia and inhibited inflammatory response after surgery. Several studies found that intraoperative use of dexmedetomidine can prevent postoperative delirium, but data were inconsistent...
April 21, 2018: BMJ Open
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