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https://www.readbyqxmd.com/read/27916577/association-of-fibrosis-in-the-infrapatellar-fat-pad-and-degenerative-cartilage-change-of-patellofemoral-joint-after-anterior-cruciate-ligament-reconstruction
#1
Kyoung Ho Yoon, Dae Hyun Tak, Taeg Su Ko, Sang Eon Park, Juhyun Nam, Sang Hak Lee
BACKGROUND: The purpose of this study was to evaluate the prevalence and risk factor of cartilage degeneration of the patellofemoral joint (PFJ) that was diagnosed by second-look arthroscopy. METHODS: One-hundred and seven patients who underwent ACL reconstruction were evaluated by preoperative MRI, postoperative MRI and second-look arthroscopy. Severity of infrapatellar fat pad (IPFP) fibrosis was evaluated by MRI at an average of 26months after ACL reconstruction...
December 1, 2016: Knee
https://www.readbyqxmd.com/read/27904791/current-concepts-in-biomechanical-interventions-for-patellofemoral-pain
#2
Richard W Willy, Erik P Meira
: Patellofemoral pain (PFP) has historically been a complex and enigmatic issue. Many of the factors thought to relate to PFP remain after patients' symptoms have resolved making their clinical importance difficult to determine. The tissue homeostasis model proposed by Dye in 2005 can assist with understanding and implementing biomechanical interventions for PFP. Under this model, the goal of interventions for PFP should be to re-establish patellofemoral joint (PFJ) homeostasis through a temporary alteration of load to the offended tissue, followed by incrementally restoring the envelope of function to the baseline level or higher...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27884055/the-association-of-forefoot-varus-deformity-with-patellofemoral-cartilage-damage-in-older-adult-cadavers
#3
Rebecca S Lufler, Joshua J Stefanik, Jingbo Niu, F Kip Sawyer, Todd M Hoagland, K Douglas Gross
INTRODUCTION: Forefoot alignment may contribute to patellofemoral joint (PFJ) osteoarthritis (OA) via its influence on the closed chain kinematics of the lower limb. The purpose of this cadaveric study was to investigate the relationship between forefoot varus and ipsilateral cartilage damage in the medial and lateral PFJ. MATERIALS AND METHODS: Forefoot alignment measurements were obtained from the feet of 25 cadavers (n=50). Cartilage damage in the medial and lateral PFJ of each knee was scored using the Outerbridge scale...
November 24, 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/27795741/hepatic-transcriptome-implications-for-palm-fruit-juice-deterrence-of-type-2-diabetes-mellitus-in-young-male-nile-rats
#4
Soon-Sen Leow, Julia Bolsinger, Andrzej Pronczuk, K C Hayes, Ravigadevi Sambanthamurthi
BACKGROUND: The Nile rat (NR, Arvicanthis niloticus) is a model of carbohydrate-induced type 2 diabetes mellitus (T2DM) and the metabolic syndrome. A previous study found that palm fruit juice (PFJ) delayed or prevented diabetes and in some cases even reversed its early stages in young NRs. However, the molecular mechanisms by which PFJ exerts these anti-diabetic effects are unknown. In this study, the transcriptomic effects of PFJ were studied in young male NRs, using microarray gene expression analysis...
2016: Genes & Nutrition
https://www.readbyqxmd.com/read/27699494/survival-and-clinical-results-of-a-modified-crosse-de-hockey-procedure-for-chronic-isolated-patellofemoral-joint-osteoarthritis-mid-term-follow-up
#5
Hiroaki Kanazawa, Yuichiro Maruyama, Katsuo Shitoto, Minoru Yokoyama, Kazuo Kaneko
BACKGROUND: The optimum treatment for isolated patellofemoral joint osteoarthritis (PFJ-OA) remains controversial. The aim of this study was to assess the mid-term clinical results of a modified crosse de hockey procedure for the treatment of isolated PFJ-OA. MATERIALS AND METHODS: We assessed 37 knees in 31 patients treated by a modified crosse de hockey procedure. The mean age was 57.6 years (range, 46-75 years) and mean follow-up was 90.1 months (range, 24-216 months)...
October 3, 2016: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/27696767/clinical-significance-of-medial-vs-lateral-compartment-patellofemoral-osteoarthritis-cross-sectional-analyses-in-an-adult-population-with-knee-pain
#6
Vincent Ukachukwu, Rachel Duncan, John Belcher, Michelle Marshall, Joshua Stefanik, Kay Crossley, Martin J Thomas, George Peat
Objective To determine the comparative prevalence, associations with selected patient characteristics and clinical outcomes of medial and lateral compartment patellofemoral joint (PFJ) osteoarthritis (OA). Methods Information was collected by questionnaires, clinical assessment and x-rays from 745 eligible community-dwelling symptomatic adults aged ≥50 years. PFJ joint space narrowing (JSN) and osteophytes (OP) were scored from skyline radiographs using the OARSI atlas. Multilevel models were used to assess associations of compartmental PFJOA with age, gender, BMI and varus/valgus malalignment, while median regression was used to examine associations with clinical outcomes (current pain intensity 0-10NRS and WOMAC Function 0-68)...
October 1, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27694510/does-location-of-patellofemoral-chondral-lesion-influence-outcome-after-oxford-medial-compartmental-knee-arthroplasty
#7
S Konan, F S Haddad
AIMS: Medial unicompartmental knee arthroplasty (UKA) is associated with successful outcomes in carefully selected patient cohorts. We hypothesised that severity and location of patellofemoral cartilage lesions significantly influences functional outcome after Oxford medial compartmental knee arthroplasty. PATIENTS AND METHODS: We reviewed 100 consecutive UKAs at minimum eight-year follow-up (96 to 132). A single surgeon performed all procedures. Patients were selected based on clinical and plain radiographic assessment...
October 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27522543/midterm-outcome-of-avon-patellofemoral-arthroplasty-for-posttraumatic-unicompartmental-osteoarthritis
#8
Sujith Konan, Fares S Haddad
BACKGROUND: Patellofemoral arthroplasties have been successfully used in the management of isolated patellofemoral joint (PFJ) osteoarthritis (OA). We hypothesized that in posttraumatic PFJ OA, isolated unicompartmental arthroplasty should be associated with reliable pain relief, patient satisfaction, and functional outcome at midterm follow-up. METHODS: Fifty-one Avon PFJ (Stryker, Mahwah, NJ) isolated unicompartmental arthroplasties (47 patients; 29 men, 18 women) were identified at a mean follow-up of 7...
July 13, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27432215/a-knee-brace-alters-patella-position-in-patellofemoral-osteoarthritis-a-study-using-weight-bearing-magnetic-resonance-imaging
#9
M J Callaghan, H Guney, N Reeves, D Bailey, K Doslikova, C Maganaris, R Hodgson, D T Felson
OBJECTIVE: To assess using weight bearing MRIs, whether a patellar brace altered patellar position and alignment in patellofemoral joint (PFJ) osteoarthritis (OA). DESIGN: Subjects age 40-70 years old with symptomatic and a radiographic K-L evidence of PFJOA. Weight bearing knee MRIs with and without a patellar brace were obtained using an upright open 0.25 Tesla scanner (G-Scan, Easote Biomedica, Italy). Five aspects of patellar position were measured: mediolateral alignment by the bisect offset index, angulation by patellar tilt, patellar height by patellar height ratio (patellar length/patellar tendon length), lateral patellofemoral contact area and finally a measurement of patellofemoral bony separation of the lateral patellar facet and the adjacent surface on the femoral trochlea (Figure 1)...
July 15, 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/27393009/structural-effects-of-sprifermin-in-knee-osteoarthritis-a-post-hoc-analysis-on-cartilage-and-non-cartilaginous-tissue-alterations-in-a-randomized-controlled-trial
#10
Frank W Roemer, Aida Aydemir, Stefan Lohmander, Michel D Crema, Monica Dias Marra, Norma Muurahainen, David T Felson, Felix Eckstein, Ali Guermazi
BACKGROUND: A recent publication on efficacy of Sprifermin for knee osteoarthritis (OA) using quantitatively MRI-defined central medial tibio-femoral compartment cartilage thickness as the structural primary endpoint reported no statistically significant dose response. However, Sprifermin was associated with statistically significant, dose-dependent reductions in loss of total and lateral tibio-femoral cartilage thickness. Based on these preliminary promising data a post-hoc analysis of secondary assessment and endpoints was performed to evaluate potential effects of Sprifermin on semi-quantitatively evaluated structural MRI parameters...
July 9, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27113220/female-adults-with-patellofemoral-pain-are-characterized-by-widespread-hyperalgesia-which-is-not-affected-immediately-by-patellofemoral-joint-loading
#11
Marcella Ferraz Pazzinatto, Danilo de Oliveira Silva, Christian Barton, Michael Skovdal Rathleff, Ronaldo Valdir Briani, Fábio Mícolis de Azevedo
OBJECTIVE: Compare pressure pain thresholds (PPTs) at the knee and a site remote to the knee in female adults with patellofemoral pain (PFP) to pain-free controls before and after a patellofemoral joint (PFJ) loading protocol designed to aggravate symptoms. DESIGN: Cross-sectional study SETTING: Participants were recruited via advertisements in fitness centers, public places for physical activity and universities. SUBJECTS: Thirty-eight females with patellofemoral pain, and 33 female pain-free controls...
October 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27100846/-psychiatric-nursing-internship-and-promotion-of-specialized-training-interest
#12
S Kasch, J Wirkner, T Klauer, H J Freyberger, S Fleßa, H Merk, R Kasch
Qualified personnel in the field of medical psychiatry are crucial to providing comprehensive care. The importance of a nursing internship as an access point to the psychiatric field is not considered by key players. A survey conducted across German medical schools in 2012 analyzed medical care internships as viewed by medical school students. From among students surveyed, those who participated in a nursing internship, and would consider taking part in further internships within the psychiatric department ("PFJ"), were separated from those who were not sure ("PFU") or who would not ("PFN") consider further study in the field of psychiatry...
April 2016: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/27052369/patella-tracking-and-patella-contact-pressure-in-modular-patellofemoral-arthroplasty-a-biomechanical-in-vitro-analysis
#13
Tilman Calliess, Max Ettinger, Ssuheib Schado, Christoph Becher, Christof Hurschler, Sven Ostermeier
INTRODUCTION: In the recent years modular partial knee prosthesis with the opportunity to combine unicompartmental tibiofemoral (UKA) and patellofemoral prosthesis (PFJ) were introduced to the clinics. To date, little is known about the biomechanics of these bi-cruciate retaining prosthetic designs. Aim of this study was to evaluate the influence of a PFJ in bicompartmental arthroplasty (UKA + PFJ) on patella tracking and retropatella pressure distribution. METHODS: A dynamic in vitro knee kinemator simulating an isokinetic extension cycle of the knee was used on eight knee specimen...
June 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/26955615/are-patellofemoral-symptoms-truly-related-to-the-patellofemoral-joint
#14
Rafik Yassa, Mahdi Yacine Khalfaoui, Andrew P Davies
PURPOSE: The pattern of symptoms of knee osteoarthritis has been thought to be indicative of specific compartment involvement. This study investigated whether there was a true correlation between patellofemoral joint (PFJ) symptoms and unicompartmental patellofemoral arthritis. MATERIALS AND METHODS: A prospective analysis of 34 patients rendered to be suffering from PFJ osteoarthritis and subsequently undergoing unicompartmental patellofemoral arthroplasty (PFA) was performed...
March 2016: Knee Surgery & related Research
https://www.readbyqxmd.com/read/26946066/patellofemoral-bone-marrow-lesions-natural-history-and-associations-with-pain-and-structure
#15
Zhaohua Zhu, Changhai Ding, Xingzhong Jin, Benny Antony, Weiyu Han, Laura L Laslett, Flavia Cicuttini, Graeme Jones
OBJECTIVE: To describe the natural history of patellofemoral joint (PFJ) bone marrow lesions (BMLs) over 2.6 years and associations between change in PFJ BMLs, knee pain and knee cartilage morphology in older adults over 5 years. METHODS: Prospective population-based cohort study of men and women aged 50-80 years (mean age 63 years, n=406) was performed. PFJ BMLs, knee cartilage volume and cartilage defect scores (0-4) were measured using Whole-Organ Magnetic Resonance Imaging Score (WORMS) system at baseline and 2...
March 4, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/26944575/effect-of-medial-patellofemoral-ligament-reconstruction-method-on-patellofemoral-contact-pressures-and-kinematics
#16
Joanna M Stephen, Christoph Kittl, Andy Williams, Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli, Christian Fink, Andrew A Amis
BACKGROUND: There remains a lack of evidence regarding the optimal method when reconstructing the medial patellofemoral ligament (MPFL) and whether some graft constructs can be more forgiving to surgical errors, such as overtensioning or tunnel malpositioning, than others. HYPOTHESIS: The null hypothesis was that there would not be a significant difference between reconstruction methods (eg, graft type and fixation) in the adverse biomechanical effects (eg, patellar maltracking or elevated articular contact pressure) resulting from surgical errors such as tunnel malpositioning or graft overtensioning...
May 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/26836287/changes-in-patellofemoral-and-tibiofemoral-joint-cartilage-damage-and-bone-marrow-lesions-over-7-years-the-multicenter-osteoarthritis-study
#17
J J Stefanik, A Guermazi, F W Roemer, G Peat, J Niu, N A Segal, C E Lewis, M Nevitt, D T Felson
OBJECTIVES: To investigate changes in cartilage damage and bone marrow lesions (BMLs) on MRI in the patellofemoral and tibiofemoral joints (TFJs) over 7 years. METHODS: The Multicenter Osteoarthritis (MOST) Study is a cohort study of persons aged 50-79 years at baseline with or at high risk for knee osteoarthritis (OA). Knees were eligible for the current study if they had knee MRI (1.0T) assessed for cartilage damage and BMLs at the baseline and 84-month visits...
July 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/26556391/the-effect-of-knee-braces-on-quadriceps-strength-and-inhibition-in-subjects-with-patellofemoral-osteoarthritis
#18
RANDOMIZED CONTROLLED TRIAL
Michael J Callaghan, Matthew J Parkes, David T Felson
STUDY DESIGN: Secondary analysis of a randomized controlled trial. BACKGROUND: The use of external supports has been questioned because they may lead to weakness in the surrounding muscles. To our knowledge, there is no investigation into the effect of knee supports or braces on quadriceps muscle strength and quadriceps inhibition in individuals with patellofemoral joint (PFJ) osteoarthritis (OA). OBJECTIVES: To investigate the effects of a flexible knee support on quadriceps maximum voluntary contraction (MVC) and arthrogenous muscle inhibition (AMI) in patients with PFJ OA...
January 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/26525514/sex-differences-in-running-mechanics-and-patellofemoral-joint-kinetics-following-an-exhaustive-run
#19
John D Willson, Justin R Loss, Richard W Willy, Stacey A Meardon
Patellofemoral joint pain (PFP) is a common running-related injury that is more prevalent in females and thought to be associated with altered running mechanics. Changes in running mechanics have been observed following an exhaustive run but have not been analyzed relative to the sex bias for PFP. The purpose of this study was to test if females demonstrate unique changes in running mechanics associated with PFP following an exhaustive run. For this study, 18 females and 17 males ran to volitional exhaustion...
November 26, 2015: Journal of Biomechanics
https://www.readbyqxmd.com/read/26471210/radiographic-progression-of-knee-osteoarthritis-is-associated-with-mri-abnormalities-in-both-the-patellofemoral-and-tibiofemoral-joint
#20
B J E de Lange-Brokaar, J Bijsterbosch, P R Kornaat, E Yusuf, A Ioan-Facsinay, A-M Zuurmond, H M Kroon, I Meulenbelt, J L Bloem, M Kloppenburg
OBJECTIVE: To investigate patterns of MRI abnormalities in the patellofemoral (PFJ) and tibiofemoral joint (TFJ) and their association with radiographic progression, using hypothesis free analyses. DESIGN: 205 patients from the GARP study with symptomatic OA at multiple sites (mean age 60 years, 80% woman, median BMI 26 kg/m(2)), underwent knee MRI at baseline. Cartilage damage, osteophytes, cysts, bone marrow lesions (BMLs) and effusion/synovitis were scored according to a validated scoring method...
March 2016: Osteoarthritis and Cartilage
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