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Soon-Sen Leow, Alice Luu, Swechhya Shrestha, K C Hayes, Ravigadevi Sambanthamurthi
Palm fruit juice (PFJ) containing oil palm phenolics is obtained as a by-product from oil palm (Elaeis guineensis) fruit milling. It contains shikimic acid, soluble fibre and various phenolic acids including p-hydroxybenzoic acid and three caffeoylshikimic acid isomers. PFJ has also demonstrated beneficial health properties in various biological models. Increasing concentrations of PFJ and different PFJ fractions were used to assess growth dynamics and possible anti-ageing properties in fruit flies (Drosophila melanogaster) genotype w1118 ...
March 14, 2018: Experimental Gerontology
S W F Middleton, A D Toms, P J Schranz, V I Mandalia
BACKGROUND: We present the largest series of Avon patellofemoral joint (PFJ) replacements outside of the design centre. There is discussion over its efficacy and usefulness. We report an independent opinion of its indications, survivorship and outcomes. METHODS: We prospectively collected demographic data and patient reported outcome measures (PROM's) on our cohort of Avon Patellofemoral replacements since its adoption in our unit in 2003 until 2014. We performed a retrospective review of radiographs...
February 20, 2018: Knee
Frank W Roemer, C Kent Kwoh, Tomoko Fujii, Michael J Hannon, Robert M Boudreau, David J Hunter, Felix Eckstein, Markus R John, Ali Guermazi
OBJECTIVE: Aims were to assess (1) structural progression in knees with no/mild radiographic osteoarthritis (ROA) (i.e. Kellgren-Lawrence (K-L) grades 0 to 2) that will undergo knee replacement (KR) during a 5-year period; (2) differences in structural damage on MRI between knees with no/mild ROA vs. those with severe ROA (i.e. K-L 3 and 4) at baseline; and (3) differences in pain levels between those groups. METHODS: All participants who underwent KR from baseline (BL) to 60 months were drawn from the Osteoarthritis Initiative...
February 13, 2018: Arthritis Care & Research
H F Hart, K M Crossley, D Felson, M Jarraya, A Guermazi, F Roemer, B Lewis, J Torner, M Nevitt, J J Stefanik
OBJECTIVE: To determine the relationship of meniscal damage to magnetic resonance imaging (MRI) features of compartment-specific patellofemoral joint (PFJ) osteoarthritis (OA) at baseline and 2 years later. METHOD: Individuals from a prospective cohort of individuals aged 50-79 with or at risk of knee OA were included. At the 60-month and 84-month study visit, Whole-Organ MRI Score (WORMS) was used to assess meniscal tears and extrusions as well as cartilage damage and bone marrow lesions (BMLs) in the medial and lateral patella and trochlea...
February 7, 2018: Osteoarthritis and Cartilage
Guilherme S Nunes, Rodrigo Scattone Silva, Ana Flávia Dos Santos, Ricardo A S Fernandes, Fábio Viadanna Serrão, Marcos de Noronha
Changes in patellofemoral joint (PFJ) stress are related to the development and course of PFJ dysfunctions. Different methods for PFJ stress calculation have been used, making the comparison of PFJ stress values across different studies difficult. The purpose of this study was to systematically review the methods for PFJ stress calculation and highlight the differences among the methods. A systematic literature search was conducted in Medline, Embase, CINAHL, SPORTDiscus and Web of Science databases. Included studies examined PFJ stress in subjects with or without musculoskeletal conditions...
December 17, 2017: Gait & Posture
Dietmar Dammerer, Michael Liebensteiner, Hannes Rochau, Christian Uprimny, Vinzenz Smekal, Ralf Rosenberger, Elvire Servien
BACKGROUND: Previous studies reported that in partial knee arthroplasty smooth transitions to the remaining native parts of the knee are important. However, in mobile-bearing unicondylar knee arthroplasty (UKA) it is mandatory to create an anterior osteochondral notch adjacent to the femoral component to get clearance for the anterior lip of the bearing in full knee extension. This notch is, however, part of the femoral trochlea. It was the aim of the study to test for a potential association between a) an obligatory anterior notch in mobile-bearing UKA located at the margin of the medial aspect of the femoral trochlea and b) postoperative patellofemoral joint (PFJ) bone remodelling and discomfort...
December 16, 2017: BMC Musculoskeletal Disorders
Gordon S Waddington
No abstract text is available yet for this article.
January 2018: Journal of Science and Medicine in Sport
Kwadwo A Owusu-Akyaw, Lauren N Heckelman, Hattie C Cutcliffe, E Grant Sutter, Zoë A Englander, Charles E Spritzer, William E Garrett, Louis E DeFrate
Anterior cruciate ligament (ACL) deficient patients have an increased rate of patellofemoral joint (PFJ) osteoarthritis (OA) as compared to the general population. Although the cause of post-injury OA is multi-factorial, alterations in joint biomechanics may predispose patients to cartilage degeneration. This study aimed to compare in vivo PFJ morphology and mechanics between ACL deficient and intact knees in subjects with unilateral ACL ruptures. Eight male subjects underwent baseline MRI scans of both knees...
January 23, 2018: Journal of Biomechanics
Clemens Gwinner, Andreas Weiler, Timm Denecke, Julian M M Rogasch, Heide Boeth, Tobias M Jung
INTRODUCTION: Posterior cruciate ligament reconstruction (PCLR) is advocated to prevent an early onset of osteoarthritis. We hypothesized that posterior instability after PCLR correlates with degenerative changes. MATERIALS AND METHODS: MRIs of 42 (12 female/30 male; 39 ± 9 years) patients were enrolled with a minimum 5-year follow-up (FFU) after PCLR. In addition, 25 contralateral and 15 follow-up MRIs (12 months after baseline) were performed. Degenerative changes were graded using WORMS...
March 2018: Archives of Orthopaedic and Trauma Surgery
Huidi Liu, Zheng Zeng, Siwen Wang, Ting Li, Emilio Mastriani, Qing-Hai Li, Hong-Xia Bao, Yu-Jie Zhou, Xiaoyu Wang, Yongfang Liu, Wei Liu, Sijing Hu, Shan Gao, Miao Yu, Yingying Qi, Zhihang Shen, Hongyue Wang, Tingting Gao, Lingqin Dong, Randal N Johnston, Shu-Lin Liu
Ovarian cancer is the third most common cancer in the female reproductive organs and epithelial ovarian cancer has the highest lethality of all gynecological cancers. Pomegranate fruit juice (PFJ) has been shown to inhibit the growth of several types of cancer other than ovarian cancer. In this study, we exposed the ovarian cancer cell line A2780 to PFJ and two of its components (ellagic acid and luteolin). MTT and wound healing assays demonstrated that all three treatments suppressed the proliferation and migration of the ovarian cancer cells...
December 2, 2017: Cancer Biology & Therapy
Donald Osarumwense, Farhan Syed, Obi Nzeako, Segun Akilapa, Omer Zubair, Jon Waite
BACKGROUND: Improved knee prosthesis designs have led to an increase in the use of patellofemoral arthroplasty as a primary treatment option in recent times. We report the early results and outcomes of the Zimmer Gender Solutions Patello-Femoral Joint (PFJ) system used to treat isolated patellofemoral osteoarthritis (PFA). METHODS: We retrospectively reviewed and analysed data of patients who underwent PFJ replacement (PFJR) at our institution with a minimum follow-up of 2 years...
September 2017: Clinics in Orthopedic Surgery
Kosuke Tajima, Chikako Shimizu, Soichiro Ohno, Yusho Nishida, Kazuhiko Udagawa, Junichi Sasaki
The suprapatellar approach for intramedullary tibial nailing has become widely accepted over the past decade. A round sleeve is passed beneath the patella to protect the surface of the patellofemoral joint (PFJ). However, the round sleeve cannot be easily stabilized in the PFJ because it does not conform to the shape of the patellar apex. Consequently, we produced a heart-shaped sleeve to simplify the insertion of the entry sleeve during the suprapatellar approach. Using the new sleeve, the following procedure is used: (1) make a longitudinal 4 cm skin incision proximal to the patella to reach the PFJ, (2) insert the guide pin manually to the ventral edge of the tibial plateau, (3) insert the cannulated trocar along the guide pin, (4) insert the heart-shaped sleeve along the cannulated trocar, (5) remove the cannulated trocar, (6) ream the entry point through the heart-shaped sleeve...
July 15, 2017: Keio Journal of Medicine
Wolf Petersen, Ingo Rembitzki, Christian Liebau
Patellofemoral pain (PFP) is a frequent cause of anterior knee pain in athletes, which affects patients with and without structural patellofemoral joint (PFJ) damage. Most younger patients do not have any structural changes to the PFJ, such as an increased Q angle and a cartilage damage. This clinical entity is known as patellofemoral pain syndrome (PFPS). Older patients usually present with signs of patellofemoral osteoarthritis (PFOA). A key factor in PFPS development is dynamic valgus of the lower extremity, which leads to lateral patellar maltracking...
2017: Open Access Journal of Sports Medicine
M Jarraya, A Guermazi, D T Felson, F W Roemer, M C Nevitt, J Torner, C E Lewis, J J Stefanik
PURPOSE: To determine the relation of superolateral Hoffa's fat pad (SHFP) hyperintensity to cartilage damage and bone marrow lesions (BMLs) in the patellofemoral joint (PFJ) and tibiofemoral joint (TFJ). METHODS: We used data from the 60 and 84-month study visits from the Multicenter Osteoarthritis (MOST) study. SHFP hyperintensity and Hoffa-synovitis were graded from 0 to 3. Cartilage damage and BMLs were scored in the PFJ and TFJ. Structural damage was defined as: any cartilage damage, full-thickness cartilage damage and any BML...
September 2017: Osteoarthritis and Cartilage
Baoming Dong, Yanliang Kong, Lei Zhang, Yongqian Qiang
The aim of the present study was to analyze the distribution and severity of cartilage damage (CD) and bone marrow edema (BME) of the patellofemoral and tibiofemoral joints (PFJ and TFJ, respectively) in patients with knee osteoarthritis (OA), and to determine whether a correlation exists between BME and CD in knee OA, using magnetic resonance imaging (MRI). Forty-five patients diagnosed with knee OA (KOA group) and 20 healthy individuals (control group) underwent sagittal multi-echo recalled gradient echo sequence scans, in addition to four conventional MR sequence scans...
May 2017: Experimental and Therapeutic Medicine
Vikram Kishor Kandhari, Mohan M Desai, Surendar S Bava, Roshan N Wade
INTRODUCTION: Patello-femoral complications are the most common complications in postoperative Total Knee Arthroplasty (TKA) patients especially overstuffing of Patello - Femoral Joint (PFJ). So, to study the effects of overstuffing of PFJ in postoperative TKA patients we put forth a new dimension - "PATELLO - FEMORAL COMPOSITE (PFC)". This is the maximum distance between anterior cortical line of femur shaft and the anterior cortex of patella with knee in full extension. AIM: To calculate chances of overstuffing of PFJ in postoperative TKA patients and document the effect of overstuffing of PFJ on the passive knee Range of Motion (ROM) in post- op TKA patients...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
Marco A Marra, Marta Strzelczak, Petra J C Heesterbeek, Sebastiaan A W van de Groes, Dennis W Janssen, Bart F J M Koopman, Ate B Wymenga, Nico J J Verdonschot
PURPOSE: In total knee arthroplasty (TKA), the posterior tibial slope is not always reconstructed correctly, and the knee ligaments may become too tight in flexion. To release a tight flexion gap, surgeons can increase the posterior tibial slope using two surgical resection techniques: the anterior tibial cortex (ACR) or the centre of tibial plateau (CPR) referencing. It is not known how this choice affects the knee laxity and function during activities of daily living. The aim of this study was to investigate the effect of tibial slope on knee laxity, kinematics and forces during a squatting activity using computer simulation techniques...
May 12, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Ronaldo V Briani, Marcella F Pazzinatto, Danilo De Oliveira Silva, Fábio M Azevedo
BACKGROUND: Physical activity levels seem to play a role in patellofemoral pain (PFP); however, few studies have been conducted to confirm this hypothesis. OBJECTIVES: To determine the reported pain levels of women with and without PFP who maintain different levels of physical activity; to determine the capability of these levels to predict pain; and to test the capability of two stair-negotiation protocols, with and without external load, to equalize pain between groups...
March 2017: Brazilian Journal of Physical Therapy
T W Hamilton, H G Pandit, D G Maurer, S J Ostlere, C Jenkins, S J Mellon, C A F Dodd, D W Murray
AIMS: It is not clear whether anterior knee pain and osteoarthritis (OA) of the patellofemoral joint (PFJ) are contraindications to medial unicompartmental knee arthroplasty (UKA). Our aim was to investigate the long-term outcome of a consecutive series of patients, some of whom had anterior knee pain and PFJ OA managed with UKA. PATIENTS AND METHODS: We assessed the ten-year functional outcomes and 15-year implant survival of 805 knees (677 patients) following medial mobile-bearing UKA...
May 2017: Bone & Joint Journal
Kay M Crossley, Anthony G Schache, Hannah Ozturk, Jonathan Lentzos, Melissa Munanto, Marcus G Pandy
Objective, Patellofemoral joint (PFJ) osteoarthritis (OA) is common, yet little is known about how this condition influences lower-limb biomechanical function. This study compared pelvis and lower-limb kinematics in people with and without PFJOA., Methods, Sixty-nine participants (64% women, mean age 56±10 years) with anterior knee pain aggravated by PFJ loaded activities (stair ambulation, rising from sitting, squatting) and radiographic lateral PFJOA on skyline radiographs were compared with 18 controls (78% women, mean age 53±7 years) with no lower-limb pain or radiographic OA...
April 24, 2017: Arthritis Care & Research
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