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Chronic migraines

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https://www.readbyqxmd.com/read/28230456/off-label-prescribing-for-children-with-migraines-in-u-s-ambulatory-care-settings
#1
L Leanne Lai, Leroy Koh, Jane Ai-Chen Ho, Alexander Ting, Augustine Obi
BACKGROUND: Migraines, Which Affect About 10% Of School-Age Children In The United States, Can Significantly Impair Quality Of Life. Despite Potential Disability, Many Children Do Not Receive Treatment Or Prophylaxis, Since Medications Specifically Approved For Children Are Significantly Less Than For Adults. There Is Also Controversy Surrounding The Apparent Widespread Practice Of Prescribing Off-Label Medications For Children With Migraines. However, Little Research Has Been Done To Identify Physician-Prescribing Patterns Of Migraine Medication For Children...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28224378/depression-and-anxiety-behaviour-in-a-rat-model-of-chronic-migraine
#2
Mingjie Zhang, Yufei Liu, Mangsuo Zhao, Wenjing Tang, Xiaolin Wang, Zhao Dong, Shengyuan Yu
BACKGROUND: Epidemiological and clinical studies have demonstrated comorbidity between migraine and affective disorders. However, it is unclear whether chronic migraine can lead to affective disorders in other animals. METHODS: A classical chronic migraine rat model (repeated dura mater inflammatory soup [IS] infusion) was used to evaluate depression and anxiety behaviour via weight, sucrose preference test, open field test and elevated plus maze test. RESULTS: We found that sucrose preference, locomotor and rearing behaviours, inner zoon distance percent, open-arm entries percent and serotonin and dopamine levels in the prefrontal cortex decreased significantly in the IS group compared with those in the control group; co-administration of low-dose amitriptyline ameliorated these deficits...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28224326/treatment-with-telmisartan-a-long-acting-angiotensin-ii-receptor-blocker-prevents-migraine-attacks-in-japanese-non-responders-to-lomerizine
#3
Ken Ikeda, Sayori Hanashiro, Yuichi Ishikawa, Masahiro Sawada, Maya Kyuzen, Harumi Morioka, Junya Ebina, Junpei Nagasawa, Masaru Yanagihashi, Ken Miura, Takehisa Hirayama, Takanori Takazawa, Osamu Kano, Kiyokazu Kawabe, Yasuo Iwasaki
Lomerizine, calcium channel blocker, is the most used medication for migraine prophylaxis in Japan. The effectiveness of this drug is reported as 50-75%. Telmisartan is angiotensin II receptor blockers which plasma half-life is 24 h. We examined whether telmisartan has preventative benefits in lomerizine non-responsive migraineurs. Lomerizine non-responders received telmisartan (20 mg/day) for 3 months after the investigation period of 3 months. Blood pressure, frequency of headache days/month, headache severity, and doses of triptans and analgesics were analyzed by Wilcoxon signed rank test...
February 21, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28220607/neurological-and-spinal-manifestations-of-the-ehlers-danlos-syndromes
#4
Fraser C Henderson, Claudiu Austin, Edward Benzel, Paolo Bolognese, Richard Ellenbogen, Clair A Francomano, Candace Ireton, Petra Klinge, Myles Koby, Donlin Long, Sunil Patel, Eric L Singman, Nicol C Voermans
The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders characterized by joint hypermobility, skin extensibility, and tissue fragility. This communication briefly reports upon the neurological manifestations that arise including the weakness of the ligaments of the craniocervical junction and spine, early disc degeneration, and the weakness of the epineurium and perineurium surrounding peripheral nerves. Entrapment, deformation, and biophysical deformative stresses exerted upon the nervous system may alter gene expression, neuronal function and phenotypic expression...
February 21, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28220376/unveiling-the-relative-efficacy-safety-and-tolerability-of-prophylactic-medications-for-migraine-pairwise-and-network-meta-analysis
#5
Aijie He, Dehua Song, Lei Zhang, Chen Li
BACKGROUND: A large number patients struggle with migraine which is classified as a chronic disorder. The relative efficacy, safety and tolerability of prophylactic medications for migraine play a key role in managing this disease. METHODS: We conducted an extensive literature search for popular prophylactic medications that are used for migraine patients. Pairwise meta-analysis and network meta-analysis (NMA) were carried out sequentially for determining the relative efficacy, safety and tolerability of prophylactic medications...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28213829/onabotulinumtoxina-effectiveness-on-chronic-migraine-negative-emotional-states-and-sleep-quality-a-single-center-prospective-cohort-study
#6
Elif Ilgaz Aydinlar, Pinar Yalinay Dikmen, Seda Kosak, Ayse Sagduyu Kocaman
BACKGROUND: OnabotulinumtoxinA (OnabotA) is considered effective in in patients with chronic migraine (CM) who failed on traditional therapies. This study was designed to evaluate the effect of OnabotA injection series on migraine outcome, negative emotional states and sleep quality in patients with CM. METHODS: A total of 190 patients with CM (mean (SD) age: 39.3 (10.2) years; 87.9% were female) were included. Data on Pittsburgh sleep quality index (PSQI), headache frequency and severity, number of analgesics used, Migraine Disability Assessment Scale...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28185239/family-impact-of-migraine-development-of-the-impact-of-migraine-on-partners-and-adolescent-children-impac-scale
#7
Richard B Lipton, Dawn C Buse, Aubrey Manack Adams, Sepideh F Varon, Kristina M Fanning, Michael L Reed
OBJECTIVE: To describe the development of the Impact of Migraine on Partners and Adolescent Children (IMPAC) scale. BACKGROUND: Although existing data and clinical experience suggest that the impact of migraine is pervasive and extends beyond the individual with migraine, no validated tools exist for assessing the impact of migraine on the family. METHODS: The Chronic Migraine Epidemiology and Outcomes (CaMEO) Study is a longitudinal study of people with migraine in the United States...
February 10, 2017: Headache
https://www.readbyqxmd.com/read/28175389/122%C3%A2-pulse-modulation-of-the-occipital-nerve-using-focused-high-intensity-ultrasound-improves-mechanical-thresholds-in-a-chronic-migraine-rat-model
#8
Ian Thomas Walling, Lucy Gee, Paul Neubauer, Lance Frith, Emery Williams, Clif Burdette, Julie G Pilitsis
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28167076/brain-network-alterations-in-the-inflammatory-soup-animal-model-of-migraine
#9
Lino Becerra, James Bishop, Gabi Barmettler, Vanessa Kainz, Rami Burstein, David Borsook
Advances in our understanding of the human pain experience have shifted much of the focus of pain research from the periphery to the brain. Current hypotheses suggest that the progression of migraine depends on abnormal functioning of neurons in multiple brain regions. Accordingly, we sought to capture functional brain changes induced by the application of an inflammatory cocktail known as inflammatory soup (IS), to the dura mater across multiple brain networks. Specifically, we aimed to determine whether IS alters additional neural networks indirectly related to the primary nociceptive pathways via the spinal cord to the thalamus and cortex...
February 3, 2017: Brain Research
https://www.readbyqxmd.com/read/28165438/morphologic-differences-of-occipital-region-in-patients-with-schizophrenia-and-migraine-headache-using-magnetic-resonance-imaging-mri-and-visual-evoked-potentials-veps
#10
Gorana Sulejmanpašić, Saida Fišeković, Senad Drnda
Aim To compare morphologic variations of occipital sulci patterns in patients with schizophrenia and migraine headache regarding gender and laterality using magnetic resonance imaging (MRI) and visual evoked potentials (VEPs) as well as damage of visual pathway in patients with schizophrenia. Methods This study included 80 patients. Brain scans and visual evoked potential responses recorded over the occipital cortex were performed to analyze the occipital region of both hemispheres. Average total volumes of both hemispheres and average values of latency of the healthy population were used for comparison...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28163508/study-of-sleep-disorders-and-polysomnographic-evaluation-among-primary-chronic-daily-headache-patients
#11
Rajesh Verma, Kamal Kumar Nagar, Ravindra Kumar Garg, Ravi Uniyal, Praveen Kumar Sharma, Sweta Pandey
OBJECTIVE: Studies related to sleep disorders and polysomnography (PSG) among chronic daily headache patients are rare. We studied this and compared chronic migraine (CM) with chronic tension-type headache. METHODS: Eighty-three patients were recruited. They were evaluated by semi-structured interview, headache, and sleep diaries along with Epworth Sleepiness Scale score and insomnia symptom score. Overnight PSG was performed and data compared. RESULTS: Chronic tension-type headache was more common than CM, both having female preponderance...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28161874/mindfulness-and-pharmacological-prophylaxis-after-withdrawal-from-medication-overuse-in-patients-with-chronic-migraine-an-effectiveness-trial-with-a-one-year-follow-up
#12
Licia Grazzi, Emanuela Sansone, Alberto Raggi, Domenico D'Amico, Andrea De Giorgio, Matilde Leonardi, Laura De Torres, Francisco Salgado-García, Frank Andrasik
BACKGROUND: Chronic Migraine (CM) is a disabling condition, worsened when associated with Medication Overuse (MO). Mindfulness is an emerging technique, effective in different pain conditions, but it has yet to be explored for CM-MO. We report the results of a study assessing a one-year course of patients' status, with the hypothesis that the effectiveness of a mindfulness-based approach would be similar to that of conventional prophylactic treatments. METHODS: Patients with CM-MO (code 1...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28151589/from-blast-to-bench-a-translational-mini-review-of-posttraumatic-headache
#13
REVIEW
Laura S Moye, Amynah A Pradhan
Current events within the military and professional sports have resulted in an increased recognition of the long-term and debilitating consequences of traumatic brain injury. Mild traumatic brain injury accounts for the majority of head injuries, and posttraumatic headache is the most common adverse effect. It is estimated that between 30% to 90% of traumatic brain injuries result in posttraumatic headache, and for a significant number of people this headache disorder can continue for up to and over a year post injury...
February 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/28146324/psychiatric-comorbidity-in-new-daily-persistent-headache-a-cross-sectional-study
#14
R Uniyal, V K Paliwal, A Tripathi
BACKGROUND: New daily persistent headache (NDPH) is a type of chronic daily headache. NDPH can have migrainous (NDPH-CM) or tension-type character (NDPH-CTTH). Recently, NDPH patients have shown to have associated anxiety and depression. We compared anxiety, depressive symptoms, somatization and pain catastrophization among NDPH, healthy controls and patients with chronic low-back pain and between NDPH-CM and NDPH-CTTH. METHODS: We assessed the study population for depressive symptoms by Patient Health Questionnaire-9, anxiety by Generalized Anxiety Disorder Scale - 7, somatoform disorder using DSM IV (TR) criteria and pain catastrophizing by using Pain Catastrophizing Scale...
February 1, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28139000/psychological-factors-associated-with-chronic-migraine-and-severe-migraine-related-disability-an-observational-study-in-a-tertiary-headache-center
#15
Elizabeth K Seng, Dawn C Buse, Jaclyn E Klepper, Sarah J Mayson, Amy S Grinberg, Brian M Grosberg, Jelena M Pavlovic, Matthew S Robbins, Sarah E Vollbracht, Richard B Lipton
OBJECTIVE: To evaluate the relationships among modifiable psychological factors and chronic migraine and severe migraine-related disability in a clinic-based sample of persons with migraine. BACKGROUND: Evidence evaluating relationships between modifiable psychological factors and chronic migraine and severe migraine-related disability is lacking in people with migraine presenting for routine clinical care. METHODS: Adults with migraine completed surveys during routinely scheduled visits to a tertiary headache center...
January 31, 2017: Headache
https://www.readbyqxmd.com/read/28127753/a-prospective-cohort-study-of-outpatient-interdisciplinary-rehabilitation-of-chronic-headache-patients
#16
Steven J Krause, Mark J Stillman, Deborah E Tepper, Deborah Zajac
OBJECTIVE: To evaluate the efficacy of an intensive outpatient program designed to improve functioning and reduce psychological impairment in chronic headache patients. BACKGROUND: Chronic headaches, occurring 15 or more days per month, for three or more months, may arise from multiple International Classification of Headache Disorders diagnoses: Chronic Migraine, Chronic Tension Type Headache, New Daily Persistent Headache, Chronic Post Traumatic Headaches, and Medication Overuse Headache...
January 27, 2017: Headache
https://www.readbyqxmd.com/read/28125248/development-of-the-cogniphobia-scale-for-headache-disorders-cs-hd-a-pilot-study
#17
Elizabeth K Seng, Jaclyn E Klepper
Cogniphobia refers to the specific fear and avoidance of cognitive exertion, which is believed to precipitate or exacerbate headache. This parallels a well-documented phenomenon, kinesiophobia (fear of movement), in chronic pain. The existing measure of cogniphobia (C-Scale) was developed in persons with posttraumatic headache, and item content may not generalize to the broader headache population. This study aimed to develop and begin the initial examination of the psychometrics of a novel measure of cogniphobia for headache disorders: The Cogniphobia Scale for Headache Disorders (CS-HD)...
January 26, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28118694/musculoskeletal-disorders-of-the-upper-cervical-spine-in-women-with-episodic-or-chronic-migraine
#18
Gabriela N Ferracini, Lidiane L Florencio, Fabíola Dach, Débora Bevilaqua Grossi, María Palacios-Ceña, Carlos Ordás-Bandera, Thais C Chaves, José G Speciali, César Fernández-DE-Las-Peñas
BACKGROUND: The role of musculoskeletal disorders of the cervical spine in migraine is under debate. AIM: To investigate differences in musculoskeletal impairments of the neck including active global and upper cervical spine mobility, the presence of symptomatic upper cervical spine joints, cervicocephalic kinesthesia and head/neck posture between women with episodic migraine, chronic migraine, and controls. DESIGN: A cross-sectional study...
January 24, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28118256/treatment-adherence-in-child-and-adolescent-chronic-migraine-patients-results-from-the-cognitive-behavioral-therapy-and-amitriptyline-trial
#19
Ashley M Kroon Van Diest, Rachelle Ramsey, Susmita Kashikar-Zuck, Shalonda Slater, Kevin Hommel, John W Kroner, Susan LeCates, Marielle A Kabbouche, Hope L O'Brien, Joanne Kacperski, Janelle R Allen, James Peugh, Andrew D Hershey, Scott W Powers
OBJECTIVES: To examine treatment adherence among children and adolescents with chronic migraine who volunteered to be in a clinical trial using three measures: treatment session attendance, therapy homework completion, and preventive medication use via daily diary. METHODS: Analyses are secondary from a trial of 135 youth aged 10 to 17 years diagnosed with chronic migraine and with a Pediatric Migraine Disability score over 20. Participants were randomly assigned to cognitive behavioral therapy plus amitriptyline (CBT+A, N=64) or headache education plus amitriptyline (HE+A, N=71)...
January 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28116559/altered-functional-connectivity-of-amygdala-underlying-the-neuromechanism-of-migraine-pathogenesis
#20
Zhiye Chen, Xiaoyan Chen, Mengqi Liu, Zhao Dong, Lin Ma, Shengyuan Yu
BACKGROUND: The amygdala is a large grey matter complex in the limbic system, and it may contribute in the neurolimbic pain network in migraine. However, the detailed neuromechanism remained to be elucidated. The objective of this study is to investigate the amygdala structural and functional changes in migraine and to elucidate the mechanism of neurolimbic pain-modulating in the migraine pathogenesis. METHODS: Conventional MRI, 3D structure images and resting state functional MRI were performed in 18 normal controls (NC), 18 patients with episodic migraine (EM), and 16 patients with chronic migraine (CM)...
December 2017: Journal of Headache and Pain
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