keyword
https://read.qxmd.com/read/38537074/development-of-the-psu-child-pump
#1
JOURNAL ARTICLE
Christopher Scheib, Raymond Newswanger, Joshua Cysyk, Karl Bohnenberger, Branka Lukic, Lichong Xu, Eric Yeager, Kirby Bletcher, Patrick Leibich, Quandashia Jackson, Heidi Flory, Mindy Tillinger, William Weiss, Gerson Rosenberg, Choon-Sik Jhun
The Pennsylvania State University (PSU) Child Pump, a centrifugal continuous-flow ventricular assist device (cf-VAD), is being developed as a suitable long-term implantable device for pediatric heart failure patients between 10 and 35 kg, body surface area (BSA) of 0.5-1.2 m2, 1-11 years of age, and requiring a mean cardiac output of 1.0-3.5 L/min. In-vitro hydraulic and hemodynamic performances were evaluated on a custom mock circulatory loop with ovine blood. Normalized index of hemolysis (NIH) was evaluated under four conditions: 1) 8,300 rpm, 3...
March 28, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38536607/echocardiographic-estimation-of-right-ventricular-diastolic-stiffness-based-on-pulmonary-regurgitant-velocity-waveform-analysis-in-precapillary-pulmonary-hypertension
#2
JOURNAL ARTICLE
Yui Nagai, Michito Murayama, Sanae Kaga, Hideki Shima, Satonori Tsuneta, Shinobu Yokoyama, Hisao Nishino, Mana Goto, Yukino Suzuki, Yusuke Yanagi, Suguru Ishizaka, Hiroyuki Iwano, Junichi Nakamura, Takahiro Sato, Ichizo Tsujino
Right ventricular (RV) diastolic stiffness is an independent predictor of survival and is strongly associated with disease severity in patients with precapillary pulmonary hypertension (PH). Therefore, a fully validated echocardiographic method for assessing RV diastolic stiffness needs to be established. This study aimed to compare echocardiography-derived RV diastolic stiffness and invasively measured pressure-volume loop-derived RV diastolic stiffness in patients with precapillary PH. We studied 50 consecutive patients with suspected or confirmed precapillary PH who underwent cardiac catheterization, magnetic resonance imaging, and echocardiography within a 1-week interval...
March 27, 2024: International Journal of Cardiovascular Imaging
https://read.qxmd.com/read/38536517/development-and-validation-of-a-risk-prediction-model-for-valve-regurgitation-in-beh%C3%A3-et-s-disease
#3
JOURNAL ARTICLE
Zixian Deng, Benhui Liang, Tangzhiming Li, Qiyun Liu, Xiaoyu Wang, Xin Sun, Ziwei Ou, Lin Zhao, Cong Xu, Huadong Liu, Jianghua Li
BACKGROUND: In Behçet's disease (BD), mild-to-severe valvular regurgitation (VR) poses a serious complication that contributes significantly to heart failure and eventually death. The accurate prediction of VR is crucial in the early stages of BD subjects for improved prognosis. Accordingly, this study aimed to develop a nomogram that can detect VR early in the course of BD. METHODS: One hundred seventy-two patients diagnosed with Behçet's disease (BD) were conducted to assess cardiac valve regurgitation as the primary outcome...
March 27, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38535104/transferring-surgical-expertise-analyzing-the-learning-curve-of-robotic-cardiac-surgery-operative-time-reduction-when-surgeon-moves-from-one-experienced-center-to-another
#4
JOURNAL ARTICLE
Sherif M Khairallah, Mohamed Rahouma, Stephanie L Mick
BACKGROUND: Robotically assisted cardiac surgery is performed in a team setting and is well known to be associated with learning curves. Surgeon and operative team learning curves are distinct entities, with total operative time representing the entire operative team (surgery, anesthesia, nursing, and perfusion) and cross-clamp time representing mainly the surgical team. Little is known about how a team learning curve evolves when an experienced surgeon transitions from one surgical center to another...
February 29, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38535097/interventricular-septal-involvement-is-associated-with-more-impaired-ventricular-function-and-mechanics-in-apical-hypertrophic-cardiomyopathy
#5
JOURNAL ARTICLE
Christos G Mihos, Tarec K Elajami, Deepika Misra, Pranav Venkataraman, Nicholas Gosdenovich, Rafle Fernandez
BACKGROUND: The interventricular septum has an important role in bi-ventricular performance. We hypothesized that septal involvement in apical hypertrophic cardiomyopathy (ApHCM-Mixed) adversely impacts ventricular structure and function when compared with isolated apical hypertrophy (ApHCM-Pure). METHODS: A total of 72 patients (ApHCM-Mixed = 36, ApHCM-Pure = 36) with serial 2D and speckle-tracking echocardiographic analyses were identified. Ventricular function and mechanics were characterized by left (LV) and right (RV) ventricular global longitudinal strain (GLS), RV free wall strain, and LV myocardial work indices, and clinical events were adjudicated...
February 21, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38533939/impact-of-prosthesis-patient-mismatch-after-surgical-aortic-valve-replacement-systematic-review-and-meta-analysis-of-reconstructed-time-to-event-data-of-122%C3%A2-989-patients-with-592%C3%A2-952-patient-years
#6
JOURNAL ARTICLE
Michel Pompeu Sá, Xander Jacquemyn, Jef Van den Eynde, Danny Chu, Derek Serna-Gallegos, Tjark Ebels, Marie-Annick Clavel, Philippe Pibarot, Ibrahim Sultan
BACKGROUND: It remains controversial whether prosthesis-patient mismatch (PPM) impacts long-term outcomes after surgical aortic valve replacement. We aimed to evaluate the association of PPM with mortality, rehospitalizations, and aortic valve reinterventions. METHODS AND RESULTS: We performed a systematic review with meta-analysis of reconstructed time-to-event data of studies published by March 2023 (according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses)...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533821/physical-activity-after-heart-surgery-associations-with-psychosocial-and-sleep-factors
#7
JOURNAL ARTICLE
Sueyeon Lee, Lauretta Quinn, Cynthia Fritschi, Anne M Fink, Chang Park, Sirimon Reutrakul, Eileen G Collins
BACKGROUND: Heart surgery is an effective intervention for managing heart disease, the leading cause of death globally. After surgery, physical activity is key to improving patients' quality of life and decreasing mortality, but patients are frequently physically inactive after heart surgery. OBJECTIVE: This cross-sectional pilot study aimed to examine how psychosocial and sleep factors influenced physical activity in patients after heart surgery. The mediating role of sleep factors between psychosocial factors and physical activity was also examined...
March 27, 2024: Western Journal of Nursing Research
https://read.qxmd.com/read/38533295/hemodynamic-determinants-of-cardiac-surgery-associated-acute-kidney-injury
#8
JOURNAL ARTICLE
Sevag Demirjian, Faisal Bakaeen, W H Wilson Tang, Chase Donaldson, Jon Taliercio, Anne Huml, Crystal A Gadegbeku, A Marc Gillinov, Steven Insler
OBJECTIVES: Examine the: 1) relative role of hemodynamic determinants of acute kidney injury (AKI) obtained in the immediate postcardiac surgery setting compared with established risk factors, 2) their predictive value, and 3) extent mediation via central venous pressure (CVP) and mean arterial pressure (MAP). DESIGN: Retrospective observational study. The main outcome of the study was moderate to severe AKI, per kidney disease: improving global outcomes, within 14 days of surgery...
April 2024: Critical care explorations
https://read.qxmd.com/read/38533144/successful-fluid-management-in-respiratory-failure-due-to-clazosentan-following-a-cerebral-aneurysm-clipping-a-case-report
#9
Hirotaka Kinoshita, Kodai Kato, Yuma Yamazaki, Eiji Hashiba, Kazuyoshi Hirota
Clazosentan, a potent selective endothelin receptor subtype A antagonist, has been demonstrated to be effective in preventing cerebral vasospasms after subarachnoid hemorrhage. We report the successful management of respiratory failure due to pulmonary edema associated with clazosentan, with a hemodynamic monitoring system. A 49-year-old Japanese man underwent emergency clipping for a right internal carotid-posterior communicating artery aneurysm. The surgery and general anesthesia for the rupture proceeded with no complications...
February 2024: Curēus
https://read.qxmd.com/read/38531800/the-value-of-combined-detection-of-serum-bnp-cardiac-troponin-i-and-dynamic-electrocardiogram-in-early-clinical-diagnosis-and-prognosis-of-patients-with-acute-myocardial-infarction
#10
JOURNAL ARTICLE
Qinxia Yu, Shuyan Yu
BACKGROUND: Acute myocardial infarction (AMI) is a prevalent cardiovascular disease resulting from myocardial ischemia and necrosis due to coronary artery occlusion. AMI is characterized by a sudden onset and high mortality, underscoring the significance of early diagnosis and treatment for improving patient prognosis. This study endeavors to assess the utility of a combined assessment involving serum brain natriuretic peptide (BNP), cardiac troponin-I (cTnI), and dynamic electrocardiogram (ECG) in the early clinical diagnosis and prognosis prediction of AMI...
March 2024: Discovery Medicine
https://read.qxmd.com/read/38531670/heart-rate-variability-analysis-in-obstructive-sleep-apnoea-patients-with-daytime-sleepiness
#11
JOURNAL ARTICLE
Seren Ucak, Hasthi U Dissanayake, Philip de Chazal, Yu Sun Bin, Kate Sutherland, Bianca Setionago, Benjamin Tong, Brendon J Yee, Kristina Kairaitis, John R Wheatley, Amanda J Piper, Peter A Cistulli
STUDY OBJECTIVES: Recent studies suggest sleepy patients with OSA are at higher risk for incident cardiovascular disease. This study assessed cardiac autonomic function in sleepy versus non-sleepy patients with obstructive sleep apnoea (OSA) using heart rate variability (HRV) analysis. We hypothesised that HRV profiles of sleepy patients would indicate higher cardiovascular risk. METHODS: Electrocardiograms (ECG) derived from polysomnograms (PSG) collected by the Sydney Sleep Biobank were used to study HRV in groups of sleepy (ESS≥10) and non-sleepy OSA patients (ESS<10)...
March 26, 2024: Sleep
https://read.qxmd.com/read/38531496/heart-rate-and-heart-rate-variability-in-obsessive-compulsive-disorder-evidence-from-patients-and-unaffected-first-degree-relatives
#12
JOURNAL ARTICLE
Franziska Jüres, Christian Kaufmann, Anja Riesel, Rosa Grützmann, Stephan Heinzel, Björn Elsner, Katharina Bey, Michael Wagner, Norbert Kathmann, Julia Klawohn
Altered heart rate (HR) and heart rate variability (HRV) are common observations in psychiatric disorders. Yet, few studies have examined these cardiac measures in obsessive-compulsive disorder (OCD). The current study aimed to investigate HR and HRV, indexed by the root mean square of successive differences (RMSSD) and further time domain indices, as putative biological characteristics of OCD. Electrocardiogram was recorded during a five-minute resting state. Group differences between patients with OCD (n = 96), healthy participants (n = 112), and unaffected first-degree relatives of patients with OCD (n = 47) were analyzed...
March 24, 2024: Biological Psychology
https://read.qxmd.com/read/38531434/an-enhanced-cardio-protective-effect-of-nanoparticles-loaded-with-active-components-from-polygonum-orientale-l-against-isoproterenol-induced-myocardial-ischemia-in-rats
#13
JOURNAL ARTICLE
Jincheng Jing, Shumei Fang, Yueting Li, Wenting Liu, Cong Wang, Yanyu Lan, Yonglin Wang, Chang Yang
In this study, nanoparticles loaded with active components from Polygonum orientale L. (PO), a traditional Chinese herb known for its anti-myocardial ischemic properties, were investigated for cardio-protective properties. Specifically, OVQ-Nanoparticles (OVQ-NPs) with Orientin (Ori), Vitexin (Vit), and Quercetin (Que) was obtained by double emulsion-solvent evaporation method. The OVQ-NPs exhibited a spherical shape, with a uniform size distribution of 136.77 ± 3.88 nm and a stable ζ-potential of -13...
March 24, 2024: International Journal of Pharmaceutics
https://read.qxmd.com/read/38530609/changes-in-cardiac-functions-in-patients-treated-with-parathyroidectomy-for-secondary-hyperparathyroidism
#14
JOURNAL ARTICLE
Sami Benli, Emrah Yesil, Deniz Tazeoglu, Cumhur Ozcan, Ismail Turkay Ozcan, Ahmet Dag
Our study aims to investigate the changes in cardiac functions, especially myocardial performance index (MPI), in patients who underwent parathyroidectomy for secondary hyperparathyroidism. Patients who underwent parathyroidectomy for secondary hyperparathyroidism between June 2010 and September 2021 were analyzed retrospectively. The patients were divided into two groups: those who underwent total parathyroidectomy (group 1) and those who underwent subtotal parathyroidectomy (group 2). The groups were compared according to the echocardiogram findings performed in the preoperative period and the postoperative sixth month...
March 26, 2024: Updates in Surgery
https://read.qxmd.com/read/38530573/association-between-elevated-body-mass-index-and-cardiac-organ-damage-in-children-and-adolescents-evidence-and-mechanisms
#15
JOURNAL ARTICLE
Alessandra Annaloro, Chiara Invernizzi, Francisco Aguilar, Julio Alvarez, Cesare Cuspidi, Guido Grassi, Empar Lurbe
INTRODUCTION: Although a number of pathophysiological aspects of childhood obesity have been reported, few information are available on obesity-related cardiac organ damage. AIM: The present study was aimed at assessing the impact of anthropometric, blood pressure (BP) and metabolic variable on cardiac structure and function in youth. METHODS: In 78 subjects aged 5-16 years attending the outpatient clinic of cardiovascular risk (Valencia, Spain) anthropometric and metabolic variables, clinic and ambulatory BP and echocardiographic parameters were assessed...
March 26, 2024: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://read.qxmd.com/read/38530173/case-327
#16
JOURNAL ARTICLE
Maxens Decavèle, Jérémie Pichon, Anne Fajac, Audrey Milon, Martine Antoine, Aude Gibelin, Antoine Parrot, Muriel Fartoukh
A 58-year-old man who was an active smoker was admitted twice to the intensive care unit (ICU) of a tertiary referral thoracic center for severe hypercapnic acute respiratory failure and persistent bilateral chest radiograph opacities that were unchanged over the course of the two ICU admissions within a 3-month period (Fig 1). He had obesity (body mass index, 36 kg/m2 ), stage 3 vascular chronic renal insufficiency, and hebephrenic schizophrenia treated with haloperidol, carbamazepine, and cyamemazine. He reported chronic dyspnea on exertion, which worsened for 6 months...
March 2024: Radiology
https://read.qxmd.com/read/38529961/right-ventricular-scalloping-index-as-cmr-derived-marker-for-diagnosis-of-arrhythmogenic-right-ventricular-cardiomyopathy
#17
JOURNAL ARTICLE
Ko-Ying Huang, Fa-Po Chung, Chao-Yu Guo, Jui-Han Chiu, Ling Kuo, Ying-Chi Lee, Ching-Yao Weng, Ying-Yueh Chang, Yenn-Jiang Lin, Chun-Ku Chen
BACKGROUND: The cardiac magnetic resonance (CMR) evaluation of right ventricular (RV) morphologic abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) is subjective. Here we aimed to use a quantitative index, the right ventricular scalloping index (RVSI), to standardize the measurement of RV free wall scalloping and aid in the imaging diagnosis. METHODS: We retrospectively included 15 patients with definite ARVC and 45 age- and sex-matched patients with idiopathic right ventricular outflow tract ventricular arrhythmia (RVOT-VA) as controls...
March 26, 2024: Journal of the Chinese Medical Association: JCMA
https://read.qxmd.com/read/38529922/-staphylococcus-aureus-bacteraemia-cardiac-implantable-electronic-device-extraction-and-the-risk-of-recurrent-infection-a-retrospective-population-based-cohort-study
#18
JOURNAL ARTICLE
Andreas Berge, Casper Carlsén, Alexandros Petropoulos, Fredrik Gadler, Magnus Rasmussen
BACKGROUND: Patients with cardiac implantable electronic device (CIED) and Staphylococcus aureus bacteraemia (SAB) are at risk of having CIED infection, pocket infection or endocarditis. To avoid treatment failures, guidelines recommend that the CIED should be extracted in all cases of SAB butrecent studies indicate low extraction rates and low risk of relapse. The aim of the study was to describe a Swedish population-based cohort of patients with CIED and SAB, the rate of extraction, and treatment failure measured as recurrent SAB...
March 26, 2024: Infectious Diseases
https://read.qxmd.com/read/38529531/translation-cultural-adaptation-and-psychometric-validation-of-the-provider-attitudes-toward-cardiac-rehabilitation-and-referral-pacrr-c-scale-in-simplified-chinese
#19
JOURNAL ARTICLE
Ding Yunmei, Cui Yan, Gu Jiayun, Sherry L Grace
BACKGROUND: The Provider Attitudes toward CR and Referral (PACRR) scale was translated into Simplified Chinese and psychometric validation ensued. METHODS: Brislin's Translation Model was applied, with two independent forward translations followed by back-translation. Experts assessed the face, content and cross-cultural validity of items, and item analysis followed. For validation, 227 physicians from hospitals in 14 Chinese provinces completed the PACRR-C. Structural validity was assessed through exploratory and confirmatory factor analysis...
March 26, 2024: Chronic Illness
https://read.qxmd.com/read/38529504/intra-neuronal-alpha-synuclein-deposition%C3%A2-is-related-to-cardiac-noradrenergic-deficiency-and-olfactory-dysfunction-in-neurogenic-orthostatic-hypotension
#20
Risa Isonaka, Patti Sullivan, Courtney Holmes, David S Goldstein
Purpose: Neurogenic orthostatic hypotension (nOH) results from deficient reflexive delivery of norepinephrine to cardiovascular receptors in response to decreased cardiac venous return. Lewy body (LB) forms of nOH entail low 18 F-dopamine-derived radioactivity (a measure of cardiac noradrenergic deficiency), olfactory dysfunction by the University of Pennsylvania Smell Identification Test (UPSIT), and increased deposition of alpha-synuclein (ɑ-syn) in dermal sympathetic noradrenergic nerves by the ɑ-syn-tyrosine hydroxylase (TH) colocalization index...
March 1, 2024: Research Square
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