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independent component analysis

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https://www.readbyqxmd.com/read/28918170/lifestyle-predictors-of-obese-and-non-obese-patients-with-nonalcoholic-fatty-liver-disease-a-cross-sectional-study
#1
Joo Hee Kwak, Dae Won Jun, Seung Min Lee, Yong Kyun Cho, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Ho Soon Choi, Byung Chul Yoon
BACKGROUND & AIMS: Most people with nonalcoholic fatty liver disease (NAFLD) are obese, and they usually eat more while being less physically active as compared to healthy individuals. However, little is known about the lifestyle patterns of non-obese or obese patients with NAFLD. The aim of this study was to investigate nutrition components and behavioral differences between non-obese and obese patients with NAFLD. METHODS: This is a cross-sectional study comprising of 209 patients...
August 30, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28917739/determination-of-fluorine-in-copper-concentrate-via-high-resolution-graphite-furnace-molecular-absorption-spectrometry-and-direct-solid-sample-analysis-comparison-of-three-target-molecules
#2
Heloisa R Cadorim, Jefferson S de Gois, Aline R Borges, Maria Goreti R Vale, Bernhard Welz, Heike Gleisner, Christina Ott
The chemical composition of complex inorganic materials, such as copper concentrate, may influence the economics of their further processing because most smelters, and particularly the producers of high-purity electrolyte copper, have strict limitations for the permissible concentration of impurities. These components might be harmful to the quality of the products, impair the production process and be hazardous to the environment. The goal of the present work is the development of a method for the determination of fluorine in copper concentrate using high-resolution graphite furnace molecular absorption spectrometry and direct solid sample analysis...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917234/association-between-complement-component-c3-and-body-composition-a-possible-obesity-inflammatory-biomarker-for-insulin-resistance
#3
Hayder A Al-Domi, Reem M Al Haj Ahmad
BACKGROUND AND OBJECTIVES: The C3 complement component (C3) is increasingly recognized as a cardiometabolic risk factor. We aimed to examine the role of C3 in insulin resistance (IR) and its association with adiposity. METHODS AND STUDY DESIGN: Sixty-seven obese (18-35 years) participants were matched with normal weight participants from the University of Jordan. BMI, waist-hip ratio (WHpR), and waist-height ratio (WHtR) were calculated. Body percent fat mass (%FM) was determined using the bioelectrical impedance analysis...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28915872/risk-factors-of-chronic-periodontitis-on-healing-response-a-multilevel-modelling-analysis
#4
J Song, H Zhao, C Pan, C Li, J Liu, Y Pan
BACKGROUND: Chronic periodontitis is a multifactorial polygenetic disease with an increasing number of associated factors that have been identified over recent decades. Longitudinal epidemiologic studies have demonstrated that the risk factors were related to the progression of the disease. A traditional multivariate regression model was used to find risk factors associated with chronic periodontitis. However, the approach requirement of standard statistical procedures demands individual independence...
September 15, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28915276/relationship-between-rectus-abdominis-muscle-thickness-and-metabolic-syndrome-in-middle-aged-men
#5
Eun Sil Choi, Soo Hyun Cho, Jung-Ha Kim
BACKGROUND AND OBJECTIVE: Skeletal muscle has been suggested as an important factor in the pathophysiology of metabolic syndrome. During the aging process, muscle mass is lost in specific body parts. However, few studies have investigated the relationship between site-specific muscle loss assessed using computed tomography (CT) and metabolic syndrome. This study was conducted to investigate the association between metabolic syndrome and rectus abdominis muscle thickness at the umbilicus level (RAM), which reflects site-specific muscle loss of the abdomen using CT image...
2017: PloS One
https://www.readbyqxmd.com/read/28914733/metabolic-connectivity-methods-and-applications
#6
Igor Yakushev, Alexander Drzezga, Christian Habeck
PURPOSE OF REVIEW: Metabolic connectivity modelling aims to detect functionally interacting brain regions based on PET recordings with the glucose analogue [F]fluorodeoxyglucose (FDG). Here, we outline the most popular metabolic connectivity methods and summarize recent applications in clinical and basic neuroscience. RECENT FINDINGS: Metabolic connectivity is modelled by various methods including a seed correlation, sparse inverse covariance estimation, independent component analysis and graph theory...
September 13, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28914659/relationship-between-alpha-rhythm-and-the-default-mode-network-an-eeg-fmri-study
#7
Anthony D Bowman, Joseph C Griffis, Kristina M Visscher, Allan C Dobbins, Timothy J Gawne, Mark W DiFrancesco, Jerzy P Szaflarski
PURPOSE: Reports of the relationship between the default mode network (DMN) and alpha power are conflicting. Our goal was to assess this relationship by analyzing concurrently obtained EEG/functional MRI data using hypothesis-independent methods. METHODS: We collected functional MRI and EEG data during eyes-closed rest in 20 participants aged 19 to 37 (10 females) and performed independent component analysis on the functional MRI data and a Hamming-windowed fast Fourier transform on the EEG data...
September 13, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28914607/cortex-wide-bold-fmri-activity-reflects-locally-recorded-slow-oscillation-associated-calcium-waves
#8
Miriam Schwalm, Florian Schmid, Lydia Wachsmuth, Hendrik Backhaus, Andrea Kronfeld, Felipe Aedo Jury, Pierre-Hugues Prouvot, Consuelo Fois, Franziska Albers, Timo van Alst, Cornelius Faber, Albrecht Stroh
Spontaneous slow oscillation-associated slow wave activity represents an internally generated state which is characterized by alternations of network quiescence and stereotypical episodes of neuronal activity - slow wave events. However, it remains unclear which macroscopic signal is related to these active periods of the slow wave rhythm. We used optic fiber-based calcium recordings of local neural populations in cortex and thalamus to detect neurophysiologically defined slow calcium waves in isoflurane anesthetized rats...
September 15, 2017: ELife
https://www.readbyqxmd.com/read/28914448/significant-burden-of-nonalcoholic-fatty-liver-disease-with-advanced-fibrosis-in-the-us-a-cross-sectional-analysis-of-2011-2014-national-health-and-nutrition-examination-survey
#9
R J Wong, B Liu, T Bhuket
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease in the US. Understanding the epidemiology of NAFLD, with specific focus on individuals with hepatic fibrosis is important to guide healthcare resource planning. AIM: To evaluate prevalence and predictors of hepatic fibrosis among US adults with NAFLD. METHODS: We performed a cross-sectional study using data from the updated 2011-2014 National Health and Nutrition Examination Survey, a national, stratified, multistage sampling survey of non-institutionalised US adults age ≥ 20...
September 15, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28912838/phylogenomics-of-colombian-helicobacter-pylori-isolates
#10
Andrés Julián Gutiérrez-Escobar, Esperanza Trujillo, Orlando Acevedo, María Mercedes Bravo
BACKGROUND: During the Spanish colonisation of South America, African slaves and Europeans arrived in the continent with their corresponding load of pathogens, including Helicobacter pylori. Colombian strains have been clustered with the hpEurope population and with the hspWestAfrica subpopulation in multilocus sequence typing (MLST) studies. However, ancestry studies have revealed the presence of population components specific to H. pylori in Colombia. The aim of this study was to perform a thorough phylogenomic analysis to describe the evolution of the Colombian urban H...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28912568/intrinsic-neural-network-dysfunction-in-quiescent-crohn-s-disease
#11
Anne K Thomann, Martin Griebe, Philipp A Thomann, Dusan Hirjak, Matthias P Ebert, Kristina Szabo, Wolfgang Reindl, Robert C Wolf
Psychological factors and comorbidities play an important role in inflammatory bowel diseases. Such comorbidity could be associated with a specific neural phenotype. Brain regions associated with emotion regulation and self-referential processing, including areas assigned to the "default mode network" (DMN), could be promising candidates in this regard. We investigated the functional integrity of multiple intrinsic neural networks in remitted patients with Crohn's disease (CD) and sought to establish relationships between neural network connectivity and psychiatric symptoms...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912479/late-stage-differentiation-of-embryonic-pancreatic-%C3%AE-cells-requires-jarid2
#12
Sara Cervantes, Marta Fontcuberta-PiSunyer, Joan-Marc Servitja, Rebeca Fernandez-Ruiz, Ainhoa García, Lidia Sanchez, Young-Sook Lee, Ramon Gomis, Rosa Gasa
Jarid2 is a component of the Polycomb Repressor complex 2 (PRC2), which is responsible for genome-wide H3K27me3 deposition, in embryonic stem cells. However, Jarid2 has also been shown to exert pleiotropic PRC2-independent actions during embryogenesis. Here, we have investigated the role of Jarid2 during pancreas development. Conditional ablation of Jarid2 in pancreatic progenitors results in reduced endocrine cell area at birth due to impaired endocrine cell differentiation and reduced prenatal proliferation...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28911257/fatigue-in-multiple-sclerosis-the-contribution-of-resting-state-functional-connectivity-reorganization
#13
Alvino Bisecco, Federica Di Nardo, Renato Docimo, Giuseppina Caiazzo, Alessandro d'Ambrosio, Simona Bonavita, Rocco Capuano, Leonardo Sinisi, Mario Cirillo, Fabrizio Esposito, Gioacchino Tedeschi, Antonio Gallo
OBJECTIVES: To investigate resting-state functional connectivity (RS-FC) of the default-mode network (DMN) and of sensorimotor network (SMN) network in relapsing remitting (RR) multiple sclerosis (MS) patients with fatigue (F) and without fatigue(NF). METHODS: In all, 59 RRMS patients and 29 healthy controls (HC) underwent magnetic resonance imaging (MRI) protocol including resting-state fMRI (RS-fMRI). Functional connectivity of the DMN and SMN was evaluated by independent component analysis (ICA)...
September 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28911071/prediction-of-pathological-response-to-neoadjuvant-treatment-in-rectal-cancer-with-a-two-protein-immunohistochemical-score-derived-from-stromal-gene-profiling
#14
S Gonçalves-Ribeiro, R Sanz-Pamplona, A Vidal, X Sanjuan, N Guillen Díaz-Maroto, A Soriano, J Guardiola, N Albert, M Martínez-Villacampa, I López, C Santos, J Serra-Musach, R Salazar, G Capellà, A Villanueva, D G Molleví
Background: Preoperative chemoradiotherapy followed by surgical mesorectal resection is the standard of care for locally advanced rectal carcinomas. Yet, predicting that patients will respond to treatment remains an unmet clinical challenge. Experimental design: Using laser-capture microdissection we isolated RNA from stroma and tumour glands from prospective pre-treatment samples (n = 15). Transcriptomic profiles were obtained hybridising PrimeView Affymetrix arrays...
September 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28910282/characterization-of-intravascular-cellular-activation-in-relationship-to-subclinical-atherosclerosis-in-postmenopausal-women
#15
Muthuvel Jayachandran, Vesna D Garovic, Michelle M Mielke, Kent R Bailey, Brian D Lahr, Virginia M Miller
OBJECTIVE: Mechanisms and interactions among intravascular cells contributing to development of subclinical atherosclerosis are poorly understood. In women, both menopausal status and pregnancy history influence progression of atherosclerosis. This study examined activation and interactions among blood elements with subclinical atherosclerosis in menopausal women with known pregnancy histories. METHODS: Carotid intima-media thickness (CIMT), as a marker of subclinical atherosclerosis, was measured using B-mode ultrasound in age- and parity-matched women [40 with and 40 without a history of preeclampsia] 35 years after the index pregnancy...
2017: PloS One
https://www.readbyqxmd.com/read/28906207/high-absolute-basophil-count-is-a-powerful-independent-predictor-of-inferior-overall-survival-in-patients-with-primary-myelofibrosis
#16
Marko Lucijanic, Ana Livun, Tajana Stoos-Veic, Vlatko Pejsa, Ozren Jaksic, David Cicic, Jelena Lucijanic, Zeljko Romic, Biserka Orehovec, Gorana Aralica, Marko Miletic, Rajko Kusec
OBJECTIVES: To investigate the clinical and prognostic significance of absolute basophil count (ABC) in patients with primary myelofibrosis (PMF). METHODS: We retrospectively investigated 58 patients with PMF treated in our institution in the period from 2006 to 2017. ABC was obtained in addition to other hematological and clinical parameters. Patients were separated into high and low ABC groups using the Receiver operating characteristic curve analysis. RESULTS: ABC was higher in PMF patients than in healthy controls (P < 0...
September 14, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/28904996/environmental-and-genetic-determinants-of-biofilm-formation-in-paracoccus-denitrificans
#17
Santosh Kumar, Stephen Spiro
The genome of the denitrifying bacterium Paracoccus denitrificans predicts the expression of a small heme-containing nitric oxide (NO) binding protein, H-NOX. The genome organization and prior work in other bacteria suggest that H-NOX interacts with a diguanylate cyclase that cyclizes GTP to make cyclic di-GMP (cdGMP). Since cdGMP frequently regulates attached growth as a biofilm, we first established conditions for biofilm development by P. denitrificans. We found that adhesion to a polystyrene surface is strongly stimulated by the addition of 10 mM Ca(2+) to rich media...
September 2017: MSphere
https://www.readbyqxmd.com/read/28902698/effect-of-educational-and-support-interventions-on-long-term-breastfeeding-rates-in-primiparous-women-a-systematic-review-and-meta-analysis
#18
Shahla Meedya, Ritin Fernandez, Kathleen Fahy
BACKGROUND: Long-term breastfeeding, including exclusive breastfeeding for six months and continuation of breastfeeding with complementary food until two years of age, has been recommended by the World Health Organization. However, despite the clear benefits of long-term breastfeeding (six months and beyond), the rates of breastfeeding still continue to remain low. Although there are some individual interventional studies that aimed to increase prolonged breastfeeding rates among both multiparous and primiparous women, there is no systematic review or meta-analysis to examine the effectiveness of those interventions among primiparous women who had no previous breastfeeding experience...
September 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28900822/an-international-review-and-meta-analysis-of-prehabilitation-compared-to-usual-care-for-cancer-patients
#19
REVIEW
C Treanor, T Kyaw, M Donnelly
PURPOSE: The purpose of the study is to systematically review and synthesise randomised controlled trials investigating the effectiveness of prehabilitation compared to usual care for newly diagnosed, adult-onset cancer patients. METHODS: MEDLINE, EMBASE, PsycINFO, CINAHL and SSCI were searched up to April 2017. Studies were included if disease-related, treatment-related, patient-reported and health service utilisation outcomes were assessed. Two reviewers independently reviewed and appraised the risk of bias of each study...
September 12, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28900390/genetically-driven-enhancement-of-dopaminergic-transmission-affects-moral-acceptability-in-females-but-not-in-males-a-pilot-study
#20
Silvia Pellegrini, Sara Palumbo, Caterina Iofrida, Erika Melissari, Giuseppina Rota, Veronica Mariotti, Teresa Anastasio, Andrea Manfrinati, Rino Rumiati, Lorella Lotto, Michela Sarlo, Pietro Pietrini
Moral behavior has been a key topic of debate for philosophy and psychology for a long time. In recent years, thanks to the development of novel methodologies in cognitive sciences, the question of how we make moral choices has expanded to the study of neurobiological correlates that subtend the mental processes involved in moral behavior. For instance, in vivo brain imaging studies have shown that distinct patterns of brain neural activity, associated with emotional response and cognitive processes, are involved in moral judgment...
2017: Frontiers in Behavioral Neuroscience
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