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Polysomnography in children

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https://www.readbyqxmd.com/read/28432036/increased-inflammation-from-childhood-to-adolescence-predicts-sleep-apnea-in-boys-a-preliminary-study
#1
Jordan Gaines, Alexandros N Vgontzas, Julio Fernandez-Mendoza, Fan He, Susan L Calhoun, Duanping Liao, Edward O Bixler
While chronic systemic inflammation in obstructive sleep apnea (OSA) has been traditionally considered a consequence of intermittent hypoxia, several treatment studies targeting inflammation suggest that this process may precede the development of the disorder. A recent cross-sectional study in the Penn State Child Cohort (PSCC) revealed that inflammation largely mediates the association between visceral adiposity and OSA in adolescence. The purpose of this study was to examine for the first time whether, longitudinally, inflammation precedes OSA during this developmental period...
April 18, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28419371/sleep-a-window-into-autonomic-control-in-children-born-preterm-and-growth-restricted
#2
Stephanie R Yiallourou, Euan M Wallace, Christie Whatley, Alexsandria Odoi, Samantha Hollis, Aidan J Weichard, Jayan Shivanandhan Muthusamy, Suraj Varma, James Cameron, Om Narayan, Rosemary Sc Horne
Study Objectives: Preterm birth and fetal growth restriction (FGR) are both associated with risk of hypertension in adulthood. Mechanisms leading to this pathology are unclear. In children aged 5-12 years, who were born preterm and FGR, we used sleep as a tool to assess autonomic control with assessment of cardiovascular structure and function. Methods: 18 children born preterm and FGR, 15 born preterm with appropriate birth weights (AGA) and 20 AGA term-born children were studied...
April 17, 2017: Sleep
https://www.readbyqxmd.com/read/28408467/isolated-mild-sleep-associated-hypoventilation-in-children-with-down-syndrome
#3
Wai Wong, Dennis Rosen
INTRODUCTION: Children with Down syndrome (DS) have a high incidence of obstructive sleep apnea (OSA) that is often associated with hypoventilation. Little is known, however, about the prevalence of sleep-associated hypoventilation independent of OSA in these children. METHODS: Retrospective chart review of all children with DS under 18 years of age undergoing polysomnography at a tertiary care paediatric hospital during a 2-year period. Exclusion criteria were as follow: those requiring oxygen or positive-pressure ventilation; with tracheostomy, baseline hypoxia, unrepaired cyanotic heart disease, pulmonary hypertension, and cerebral palsy; or OSA with >5 obstructions/hour...
April 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28395495/-characteristics-of-sleep-apnea-events-in-non-snoring-children
#4
Z F Xu, X D Li, Y X Wu, J Tai, Y M Zhang, X X Peng, L Zheng, J Shi, X Ni
Objective: To investigate the characteristics of sleep-related respiratory events in normal children and to provide normal polysomnographic parameters for diagnosing sleep-disordered breathing in children. Methods: Normal subjects between 3 and 14 years old were enrolled from 1 July 2014 to 31 December 2015 and the subjects received overnight polysomnography at the sleep center of our hospital. They were children of our hospital employees or were recruited from the communities who did not have sleep and respiratory disorders...
March 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28393717/leptin-levels-in-children-with-obstructive-sleep-apnea-syndrome
#5
Ayhan Söğüt, Şerefden Açıkgöz, Lokman Uzun, Mehmet Birol Uğur, Remzi Altın, Elif Dağlı, Athanasios Kaditis, Refika Ersu
Introduction: The aim of this study is to assess the effect of obstructive sleep apnea syndrome (OSAS) severity on leptin levels in children. Patients and Methods: Children with habitual snoring underwent overnight polysomnography. Fasting venous blood samples were obtained between 8 AM and 9 AM, following the night of the sleep study. Children with an apnea-hypopnea index of ≥ 5/h were included in the moderate-to-severe OSAS group while those with an apnea-hypopnea index of < 5/h formed the mild OSAS/primary snoring group...
December 2016: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/28382434/evaluation-of-the-central-sleep-apnea-in-asymptomatic-children-with-chiari-1-malformation-an-open-question
#6
Marco Zaffanello, Francesco Sala, Luca Sacchetto, Emma Gasperi, Giorgio Piacentini
INTRODUCTION: Type I is the most common Chiari malformation in children. In this condition, the lower part of the cerebellum, but not the brain stem, extends into the foramen magnum at the base of the skull leading to intermittent brain hypertension. In symptomatic children, central sleep apneas are shown in polysomnography evaluation. A central apnea index of 1/h or more is considered abnormal, but >5/h is clearly considered pathological. Therefore, central sleep apnea evaluation in pediatric age may show great age-related variability...
April 5, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28366348/quality-of-life-and-excessive-daytime-sleepiness-in-children-and-adolescents-with-myotonic-dystrophy-type-1
#7
Genevieve Ho, John Widger, Michael Cardamone, Michelle A Farrar
OBJECTIVES: Myotonic dystrophy type 1 (DM1) is an autosomal dominant neuromuscular disease with variable severity that affects all ages. Sleepiness is an important co-morbidity affecting a large proportion of paediatric DM1 patients. The current study examined the relationship between sleepiness and quality of life in a paediatric DM1 cohort. METHODS: A cross-sectional study was conducted in children and adolescents with DM1 attending a multi-disciplinary neuromuscular clinic in a tertiary paediatric centre...
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28366347/sleep-disturbance-in-pediatric-patients-on-automated-peritoneal-dialysis
#8
Cláudia Gomes, Lia Oliveira, Rosário Ferreira, Carla Simão
OBJECTIVE: There are few reports describing sleep disturbance (SD) in children on automated peritoneal dialysis (APD), and they are mostly based on the application of questionnaires. As far as we know, only two studies used polysomnography (PSG), the gold standard for the diagnosis of SD. This is the first study assessing SD in children with chronic kidney disease (CKD) on APD in our country. METHODS: This was an observational and descriptive study. Children up to 18 years of age who had undergone APD for a minimum of three months were considered eligible...
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28366141/-leptin-levels-in-children-with-obstructive-sleep-apnea-syndrome
#9
Ayhan Söğüt, Şerefden Açıkgöz, Lokman Uzun, Mehmet Birol Uğur, Remzi Altın, Elif Dağlı, Athanasios Kaditis, Refika Ersu
Introduction: The aim of this study is to assess the effect of obstructive sleep apnea syndrome (OSAS) severity on leptin levels in children. Patients and Methods: Children with habitual snoring underwent overnight polysomnography. Fasting venous blood samples were obtained between 8 AM and 9 AM, following the night of the sleep study. Children with an apnea-hypopnea index of ≥ 5/h were included in the moderate-to-severe OSAS group while those with an apnea-hypopnea index of < 5/h formed the mild OSAS/primary snoring group...
December 2016: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/28364431/validation-of-the-sonomat-against-psg-and-quantitative-measurement-of-partial-upper-airway-obstruction-in-children-with-sleep-disordered-breathing
#10
Mark B Norman, Sonia M Pithers, Arthur Y Teng, Karen A Waters, Colin E Sullivan
Study Objectives: To validate the Sonomat against polysomnography (PSG) metrics in children and to objectively measure snoring and stertor to produce a quantitative indicator of partial upper airway obstruction that accurately reflects the pathology of pediatric sleep-disordered breathing (SDB). Methods: Simultaneous PSG and Sonomat recordings were performed in 76 children (46 male, age 5.8 ± 2.8, BMI = 18.5 ± 3.8 kg/m2). Sleep time, individual respiratory events and the apnea/hypopnea index (AHI) were compared...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28364411/urinary-cysteinyl-leukotriene-e4-level-and-therapeutic-response-to-montelukast-in-children-with-mild-obstructive-sleep-apnea
#11
Kanokkarn Sunkonkit, Suchada Sritippayawan, Montida Veeravikrom, Jitladda Deerojanawong, Nuanchan Prapphal
BACKGROUND: Antileukotriene has been used for alleviating disease severity in children with adenotonsillar hypertrophy (ATH) and mild obstructive sleep apnea (OSA). Previous study showed the relationship between urinary cysteinyl leukotriene E₄ (uLTE₄) level and therapeutic response to montelukast in asthmatic adults. However, this relationship has never been investigated in pediatric OSA. OBJECTIVES: To determine the relationship between uLTE₄ level and therapeutic response to montelukast in children with ATH and mild OSA...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28356179/upper-airway-reflexes-are-preserved-during-dexmedetomidine-sedation-in-children-with-down-syndrome-and-obstructive-sleep-apnea
#12
Mohamed Mahmoud, Stacey L Ishman, Keith McConnell, Robert Fleck, Sally Shott, Goutham Mylavarapu, Ephraim Gutmark, Yuanshu Zou, Rhonda Szczesniak, Raouf S Amin
STUDY OBJECTIVES: The assessment of pharyngeal collapsibility is difficult to perform in children under normal sleep. An alternative is to perform the assessment under an anesthetic, such as dexmedetomidine (DEX), that induces non-rapid eye movement (NREM) sleep. The objectives of this study were to compare critical closing airway pressure (Pcrit) obtained during natural sleep to that obtained under DEX in patients with Down syndrome (DS) and persistent obstructive sleep apnea (OSA) and determine whether Pcrit measured under sedation predicts the severity of OSA...
February 20, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28356178/autotitrating-cpap-as-a-tool-for-cpap-initiation-for-children
#13
Rebecca Mihai, Moya Vandeleur, Sally Pecoraro, Margot J Davey, Gillian M Nixon
STUDY OBJECTIVES: Few studies have assessed autotitrating positive airway pressure (autoPAP) for treatment of obstructive sleep apnea (OSA) in children. We aimed to review our use of autoPAP for initiation of continuous positive airway pressure (CPAP) therapy in children, and compare autoPAP-derived treatment pressures to CPAP treatment pressure determined by attended polysomnography (PSG). METHODS: Retrospective review of children initiated on autoPAP from 2013 to 2015...
February 20, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28356177/automated-screening-of-children-with-obstructive-sleep-apnea-using-nocturnal-oximetry-an-alternative-to-respiratory-polygraphy-in-unattended-settings
#14
Daniel Álvarez, María L Alonso-Álvarez, Gonzalo C Gutiérrez-Tobal, Andrea Crespo, Leila Kheirandish-Gozal, Roberto Hornero, David Gozal, Joaquín Terán-Santos, Félix Del Campo
STUDY OBJECTIVES: Nocturnal oximetry has become known as a simple, readily available, and potentially useful diagnostic tool of childhood obstructive sleep apnea (OSA). However, at-home respiratory polygraphy (HRP) remains the preferred alternative to polysomnography (PSG) in unattended settings. The aim of this study was twofold: (1) to design and assess a novel methodology for pediatric OSA screening based on automated analysis of at-home oxyhemoglobin saturation (SpO2), and (2) to compare its diagnostic performance with HRP...
March 14, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28320866/adenotonsillotomy-versus-adenotonsillectomy-in-pediatric-obstructive-sleep-apnea-an-rct
#15
Anna Borgström, Pia Nerfeldt, Danielle Friberg
BACKGROUND: Adenotonsillectomy (ATE) is a well-established and effective treatment of pediatric obstructive sleep apnea (OSA). In recent years, a more conservative method, adenotonsillotomy (ATT), has gained popularity because it is associated with less postoperative morbidity. Yet no previous randomized study has compared these 2 methods regarding their effectiveness in treating pediatric OSA in terms of polysomnographic data, which was the primary aim of this study. The hypothesis was that ATT is noninferior to ATE after 1 year...
March 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28320844/the-effects-of-obstructive-sleep-apnea-syndrome-on-the-dentate-gyrus-and-learning-and-memory-in-children
#16
Jiook Cha, Johanna A Zea-Hernandez, Sanghun Sin, Katharina Graw-Panzer, Keivan Shifteh, Carmen R Isasi, Mark E Wagshul, Eileen E Moran, Jonathan Posner, Molly E Zimmerman, Raanan Arens
Obstructive sleep apnea syndrome (OSAS) is associated with intermittent hypoxia and sleep loss. In children, impairments of cognitive function are important manifestations, but the underlying pathology is unknown. We hypothesized that OSAS would affect the dentate gyrus, a hippocampal subdivision essential to neurogenesis and cognition, and that this impact would further affect cognitive function in children. In children with OSAS (n = 11) and control subjects (n = 12; age and sex matched), we performed diffusion tensor imaging and structural MRI, polysomnography, and neuropsychological assessments...
April 19, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28281031/pulse-transit-time-as-a-tool-to-characterize-obstructive-and-central-apneas-in-children
#17
Lucie Griffon, Alessandro Amaddeo, Jorge Olmo Arroyo, Rossana Tenconi, Serena Caggiano, Sonia Khirani, Brigitte Fauroux
PURPOSE: The characterization of apneas during polysomnography (PSG) as obstructive or central is a key element of a sleep study. Pulse transit time (PTT) has demonstrated its potential as a noninvasive surrogate marker for inspiratory efforts. The aim of the study was to assess the ability of PTT to classify apneas as central or obstructive, as compared to respiratory inductance plethysmography (RIP) in children. METHODS: Overnight PSG with simultaneous PTT recording was performed on 11 consecutive children (mean age 8...
March 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28269370/bed-based-instrumentation-for-unobtrusive-sleep-quality-assessment-in-severely-disabled-autistic-children
#18
Charles Carlson, Ahmad Suliman, Punit Prakash, David Thompson, Shangxian Wang, Bala Natarajan, Steve Warren
The relationship between sleep quality and daytime wellness and performance in severely disabled, autistic children is not well understood. While polysomnography and, more recently, actigraphy serve as means to obtain sleep assessment data from neurotypical children and adults, these techniques are not well-suited to severely autistic children. This paper presents recent progress on a bed sensor suite that can unobtrusively track physiological and behavioral parameters used to assess sleep quality. Electromechanical films and load cells provide data that yield heart rate, respiration rate, center of position, in-and-out-of-bed activity, and general movement, while thermocouples are used to detect bed-wetting events...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268987/identifying-individual-sleep-apnea-hypoapnea-epochs-using-smartphone-based-pulse-oximetry
#19
Ainara Garde, Parastoo Dekhordi, J Mark Ansermino, Guy A Dumont
Sleep apnea, characterized by frequent pauses in breathing during sleep, poses a serious threat to the healthy growth and development of children. Polysomnography (PSG), the gold standard for sleep apnea diagnosis, is resource intensive and confined to sleep laboratories, thus reducing its accessibility. Pulse oximetry alone, providing blood oxygen saturation (SpO2) and blood volume changes in tissue (PPG), has the potential to identify children with sleep apnea. Thus, we aim to develop a tool for at-home sleep apnea screening that provides a detailed and automated 30 sec epoch-by-epoch sleep apnea analysis...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267299/predicting-the-effect-of-treatment-in-paediatric-osa-by-clinical-examination-and-functional-respiratory-imaging
#20
Monique Slaats, Wim Vos, Cedric Van Holsbeke, Jan De Backer, Dieter Loterman, Wilfried De Backer, An Boudewyns, Stijn Verhulst
OBJECTIVE: The aim of this study was to investigate whether functional respiratory imaging (FRI) or clinical examination could predict treatment outcome for obstructive sleep apnea (OSA) in normal-weight, non-syndromic children. METHODS: Normal weight children diagnosed with OSA by polysomnography were prospectively included. All children got a thorough evaluation and an ultra-low dose computed tomography scan of the upper airway (UA). A 3-D reconstruction was built combined with computational fluid dynamics for FRI...
March 7, 2017: Pediatric Pulmonology
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