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Polysomnography in children

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https://www.readbyqxmd.com/read/29323933/cardioventilatory-control-in-preterm-born-children-and-the-risk-of-obstructive-sleep-apnea
#1
Keren Armoni Domany, Md Monir Hossain, Leonardo Nava-Guerra, Michael C Khoo, Keith McConnell, John L Carroll, Yuanfang Xu, Mark DiFrancesco, Raouf S Amin
Rationale The contribution of ventilatory control to the pathogenesis of obstructive sleep apnea (OSA) in preterm born children is unknown. Objectives To characterize phenotypes of ventilatory control that are associated with the presence of OSA in preterm born children during early childhood. Methods Preterm and term born children without comorbid conditions were enrolled. They were categorized into OSA group and non-OSA group based on polysomnography. Measurements Loop gain, controller gain and plant gain, reflecting ventilatory instability, chemoreceptor sensitivity and blood gas response to a change in ventilation, respectively, were estimated from spontaneous sighs identified during polysomnography...
January 11, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29314419/convergent-validity-of-actigraphy-with-polysomnography-and-parent-reports-when-measuring-sleep-in-children-with-down-syndrome
#2
A J Esbensen, E K Hoffman, E Stansberry, R Shaffer
BACKGROUND: There is a need for rigorous measures of sleep in children with Down syndrome as sleep is a substantial problem in this population and there are barriers to obtaining the gold standard polysomnography (PSG). PSG is cost-prohibitive when measuring treatment effects in some clinical trials, and children with Down syndrome may not cooperate with undergoing a PSG. Minimal information is available on the validity of alternative methods of assessing sleep in children with Down syndrome, such as actigraphy and parent ratings...
January 5, 2018: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29305826/hepcidin-soluble-transferrin-receptor-and-il-6-levels-in-obese-children-and-adolescents-with-and-without-type-2-diabetes-mellitus-impaired-glucose-tolerance-and-their-association-with-obstructive-sleep-apnea
#3
S Shalitin, V Deutsch, R Tauman
PURPOSE: Obesity, type 2 diabetes mellitus (T2DM), and obstructive sleep apnea (OSA) are associated with chronic low-grade inflammation. Iron metabolism is linked with insulin-resistant states and with OSA in adults. The association of body iron status with T2DM in children remains undefined. We aimed to evaluate plasma interleukin-6 (IL-6), hepcidin, and soluble transferrin receptor (sTfR) levels in obese patients with T2DM or impaired glucose tolerance (IGT) and in those without, and the contribution of OSA to their levels...
January 5, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29304420/local-changes-in-computational-non-rapid-eye-movement-sleep-depth-in-infants
#4
Anna-Liisa Satomaa, Outi Saarenpää-Heikkilä, Eero Huupponen, Turkka Kirjavainen, Juhani Heinonen, Sari-Leena Himanen
OBJECTIVE: Deep NREM sleep and its hallmark EEG phenomenon slow wave activity (SWA) are under homeostatic control in adults. SWA is also locally regulated as it increases in the brain areas that have been used intensively. Moreover, in children, SWA is a marker of cortical maturation. In the present study the local properties of NREM sleep depth were evaluated using the quantitative mean frequency method. We aimed to study if age is related to NREM sleep depth in young infants. In addition, we studied if young infants have local differences in their NREM sleep...
October 16, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29246269/adult-onset-sleepwalking-secondary-to-hyperthyroidism-polygraphic-evidence
#5
Loretta Giuliano, Daniela Fatuzzo, Greta Mainieri, Sandro La Vignera, Vito Sofia, Mario Zappia
Sleepwalking is a disorder characterized by complex motor behaviors arising from slow wave sleep usually occurring in children. The adult onset of sleepwalking suggests the presence of an external precipitating factor leading to the occurrence of the disorder. Hyperthyroidism has been reported to be the possible cause of sleepwalking in a few cases. We present the case of a 36-year-old man who reported a sudden appearance of nocturnal episodes of sleepwalking. He underwent a complete video polysomnography (VPSG), which showed a polygraphic pattern arising from stage N3 sleep related to the presence of simple motor behaviors...
December 13, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29236274/outcomes-of-adenotonsillectomy-in-severe-pediatric-obstructive-sleep-apnea
#6
Karim El-Kersh, Rodrigo Cavallazzi, Egambaram Senthilvel
We conducted a retrospective chart review to examine the efficacy of adenotonsillectomy for the treatment of severe obstructive sleep apnea (OSA) in children. Our study population was made up of 85 patients-58 boys and 27 girls, aged 1 to 17 years (mean: 6.9 ± 4.4)-with severe OSA who had undergone adenotonsillectomy and pre- and postoperative attended polysomnography (PSG) over a 4-year period. Severe OSA was defined as an apnea-hypopnea index (AHI) of >10 events per hour of sleep. Patients who had an underlying genetic or craniofacial anomaly were excluded...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29232179/adenotonsillectomy-for-obstructive-sleep-apnea-in-children-with-complex-chronic-conditions
#7
Reshma Amin, Theresa Holler, Indra Narang, Sharon L Cushing, Evan J Propst, Suhail Al-Saleh
Objective To estimate the prevalence of persistent obstructive sleep apnea postadenotonsillectomy in children with complex chronic conditions. Study Design A retrospective cohort study. Setting The Hospital for Sick Children Sleep laboratory. Subjects Children ≤18 years of age who had moderate to severe obstructive sleep apnea and had polysomnography pre- and postadenotonsillectomy. Methods Medical and polysomnographic data were reviewed. The prevalence of persistent obstructive sleep apnea postadenotonsillectomy was determined for the following groups: no complex chronic conditions, single-system complex chronic conditions, and multisystem complex chronic conditions...
December 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29217599/ers-statement-on-obstructive-sleep-disordered-breathing-in-1-to-23-month-old-children
#8
Athanasios G Kaditis, Maria Luz Alonso Alvarez, An Boudewyns, Francois Abel, Emmanouel I Alexopoulos, Refika Ersu, Koen Joosten, Helena Larramona, Silvia Miano, Indra Narang, Hui-Leng Tan, Ha Trang, Marina Tsaoussoglou, Nele Vandenbussche, Maria Pia Villa, Dick Van Waardenburg, Silke Weber, Stijn Verhulst
The present statement was produced by a European Respiratory Society Task Force to summarise the evidence and current practice on the diagnosis and management of obstructive sleep disordered breathing (SDB) in children aged 1-23 months. A systematic literature search was completed and 159 articles were summarised to answer clinically relevant questions. SDB is suspected when symptoms or abnormalities related to upper airway obstruction are identified. Morbidity (pulmonary hypertension, growth delay, behavioural problems) and coexisting conditions (feeding difficulties, recurrent otitis media) may be present...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29215159/sleep-disorders-in-obese-children-are-not-limited-to-obstructive-sleep-apnoea-syndrome
#9
C Carriere, O Coste, M C Meiffred-Drouet, P Barat, H Thibault
AIM: This study was to characterised respiratory and non-respiratory sleep disorders in obese children and evaluated the diagnostic and therapeutic impact of a specific sleep consultation. METHODS: A descriptive study was conducted in obese French children who received multidisciplinary care management from the hospital centre for paediatric obesity in Bordeaux. This followed a specific sleep consultation between 2007 and 2015, because their paediatrician had identified symptoms suggestive of sleep disorders...
December 7, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29205091/polysomnographic-oxygen-saturation-findings-for-preteen-children-versus-adolescents
#10
Nathan D Wiebracht, Shan He, Colin Cotton, Jareen Meinzen-Derr, Gordon Shott, David F Smith, Keith B McConnell, Stacey L Ishman
Objective Home oximetry is commonly used to screen for obstructive sleep apnea (OSA) in children; however, normal oxygen desaturation levels by disease severity are not well known. It was our objective to determine if oxygen saturation levels differed by OSA severity category in children and if these differences were similar for preteen children and adolescents. Study Design Retrospective case series of children undergoing polysomnography from September 2011 to July 2015. Setting Tertiary pediatric hospital...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29202882/age-and-seasons-influence-on-at-home-pulse-oximetry-results-in-children-evaluated-for-suspected-obstructive-sleep-apnea
#11
Martino Pavone, Elisabetta Verrillo, Nicola Ullmann, Serena Caggiano, Valentina Negro, Renato Cutrera
BACKGROUND: Seasonal variability on obstructive sleep apnea has already been studied by polysomnography in children. Winter and spring season emerged as critical periods. No data are currently available for pulse oximetry performed at home. The aim of our study was to evaluate the effect of seasonality and age on the results of at-home pulse oximetry performed in children referred for suspected OSA. METHODS: We retrospectively studied 781 children (64.3% Males), aged 4...
December 4, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29198306/sleep-architecture-in-children-with-common-phenotype-of-obstructive-sleep-apnea
#12
Peter Durdik, Anna Sujanska, Stanislava Suroviakova, Melania Evangelisti, Peter Banovcin, Maria Pia Villa
STUDY OBJECTIVES: In children, the effect of the common phenotype of obstructive sleep apnea (OSA) on sleep architecture is not adequately documented. The aim of this study was to evaluate sleep architecture in a pediatric population with the common phenotype of OSA. METHODS: The prospective cross-sectional study included 116 children in the age range of 3 to 8 years with suspected OSA and 51 healthy children. All children underwent standard overnight in-laboratory video polysomnography...
November 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29198292/polysomnography-detected-bruxism-in-children-is-associated-with-somatic-complaints-but-not-anxiety
#13
Candice A Alfano, Joanne L Bower, Jessica M Meers
STUDY OBJECTIVES: Sleep bruxism (SB) is common in children and is associated with somatic symptoms and sleep disturbance. Etiological theories posit the role of anxiety, suggesting youth with anxiety disorders may be at high risk for SB, but empirical data are lacking. Furthermore, parent report rather than polysomnography (PSG) has been used to examine SB-anxiety relationships in children. We examined rates of PSG-detected compared to parent-reported SB in children with generalized anxiety disorder (GAD) and healthy controls...
November 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29193443/a-review-of-sleep-disturbance-in-children-and-adolescents-with-anxiety
#14
REVIEW
Wilson J Brown, Allison K Wilkerson, Stephen J Boyd, Daniel Dewey, Franklin Mesa, Brian E Bunnell
The present review examines the relations between sleep disturbance and anxiety in children and adolescents. The review begins with a detailed discussion of normative developmental trends in sleep, and the relation between sleep quality and emotion dysregulation in children. The extant literature on sleep disturbance in clinically anxious children with a focus on subjective versus objective measures of sleep is then summarized in detail. Finally, a review of the reciprocal relationship between sleep and emotion regulation is provided...
November 28, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/29168015/ascending-aortic-blood-flow-velocity-is-increased-in-children-with-primary-snoring-mild-sleep-disordered-breathing-and-associated-with-an-increase-in-cd8-%C3%A2-t-cells-expressing-tnf%C3%AE-and-ifn%C3%AE
#15
Anna Kontos, Scott Willoughby, Cameron van den Heuvel, Declan Kennedy, James Martin, Greg Hodge, Matthew Worthley, Adelene Kaihui Chin, Adam Nelson, Karen Teo, Mathias Baumert, Yvonne Pamula, Kurt Lushington
Sleep-disordered breathing (SDB) is associated with cardiovascular disease and systemic inflammation in adults but this remains to be explored in children, especially in children with the most common form of SDB, i.e. primary snoring/mild SDB. This pilot study investigated the relationship between the cardiovascular function and inflammation in children with mild SDB. Nineteen participants aged 5-14 years underwent overnight polysomnography, cardiac magnetic resonance imaging (aortic blood flow velocity and left and right ventricular systolic function) and assessment for inflammatory markers (intracellular cytokine analysis of T cells by flow cytometry)...
November 22, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29165677/being-born-too-small-and-too-early-may-alter-sleep-in-childhood
#16
Stephanie R Yiallourou, Bianca C Arena, Euan M Wallace, Alexsandria Odoi, Samantha Hollis, Aidan Weichard, Rosemary S C Horne
Study Objectives: Fetal growth restriction (FGR) occurs in up to 10% of pregnancies and is associated with increased risk of prematurity and neurodevelopmental impairment. FGR also alters sleep state distribution in utero and maturation in infancy. Currently, limited data on the long-term associations of FGR and childhood sleep exist. Accordingly, we assessed the associations between preterm birth and FGR and sleep in children aged 5-12 years. Methods: 17 children born preterm and FGR, 15 children born preterm but appropriately grown (AGA) and 20 term AGA children (controls) were studied using overnight polysomnography...
November 20, 2017: Sleep
https://www.readbyqxmd.com/read/29164334/association-between-fentanyl-test-results-and-rescue-morphine-requirements-in-children-after-adenotonsillectomy
#17
Yi-Hang Li, Xuan Wang, Zhi-Jian Zhou, Pei-Jun Zhuang
PURPOSE: Preoperative sleep study helps to predict post-adenotonsillectomy morphine requirements. However, in some institutions, many suspected children with obstructive sleep apnoea syndrome have an adenotonsillectomy without polysomnography assessments. This study investigated the relationship between the results of a fentanyl test performed before extubation and the postoperative morphine requirements in children after adenotonsillectomy. METHODS: Intravenous fentanyl (1 µg/kg) was given as a test before extubation when spontaneous ventilation was restored in 80 children aged 3-7 years who underwent adenotonsillectomy...
November 21, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/29157589/overweight-and-obesity-add-to-behavioral-problems-in-children-with-sleep-disordered-breathing
#18
Sarah N Biggs, Knarik Tamanyan, Lisa M Walter, Aidan J Weichard, Margot J Davey, Gillian M Nixon, Rosemary S C Horne
OBJECTIVE: This study aimed to determine whether overweight and obesity increased the detrimental effects of pediatric sleep-disordered breathing (SDB) on cognition, behavior, mood, and quality of life. METHODS: Children and adolescents (8-16 years) with clinically diagnosed SDB were categorized into two groups: healthy weight (Body Mass Index (BMI) z-score <1.04, N = 11) and overweight/obese (BMI z-score ≥ 1.04, N = 10). Age-matched healthy weight, non-snoring controls (N = 25) were recruited from the community...
November 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29117883/admission-criteria-for-children-with-obstructive-sleep-apnea-after-adenotonsillectomy-considerations-for-cost
#19
David F Smith, Charlene P Spiceland, Stacey L Ishman, Branden M Engorn, Christopher Donohue, Paul S Park, James R Benke, Tiffany Frazee, Robert H Brown, Nicholas M Dalesio
STUDY OBJECTIVES: Postoperative respiratory complications (PRCs) are common among children with obstructive sleep apnea (OSA) after adenotonsillectomy. We analyzed postoperative admission guidelines to determine which optimally balanced patient safety and cost. METHODS: Retrospective study of children aged 12 years or younger undergoing adenotonsillectomy for OSA after polysomnography at a tertiary academic care center over 2 years. Demographics, medical history, and hospital course were collected...
November 1, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29110581/outcomes-of-drug-induced-sleep-endoscopy-directed-surgery-for-pediatric-obstructive-sleep-apnea
#20
Shan He, Nithin S Peddireddy, David F Smith, Angela L Duggins, Christine Heubi, Sally R Shott, Stacey L Ishman
Objectives To determine the effectiveness of pediatric drug-induced sleep endoscopy (DISE)-directed surgery for children with infant obstructive sleep apnea (OSA) or OSA after adenotonsillectomy. Study Design Case series with chart review. Setting Tertiary care pediatric hospital. Subjects and Methods We included 56 children undergoing DISE from October 2013 to September 2015 who underwent subsequent surgery to address OSA. The primary outcome was successful response to DISE-directed surgery based on the postoperative obstructive Apnea-Hypopnea Index (oAHI)...
November 1, 2017: Otolaryngology—Head and Neck Surgery
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