keyword
MENU ▼
Read by QxMD icon Read
search

connectivity

keyword
https://www.readbyqxmd.com/read/29679816/poor-mental-health-among-low-income-women-in-the-u-s-the-roles-of-adverse-childhood-and-adult-experiences
#1
Joshua P Mersky, Colleen E Janczewski, Jenna C Nitkowski
RATIONALE: It is well established that exposure to a greater number of adverse childhood experiences (ACEs) increases the risk of poor physical and mental health outcomes. Given the predictive validity of ACE scores and other cumulative risk metrics, a similar measurement approach may advance the study of risk in adulthood. OBJECTIVE: We examined the prevalence and interrelations of 10 adverse adult experiences, including household events such as intimate partner violence and extrafamilial events such as crime victimization...
April 14, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29679722/pulmonary-lymphatic-vessel-morphology-a-review
#2
REVIEW
E Weber, F Sozio, A Borghini, P Sestini, E Renzoni
Our understanding of lymphatic vessels has been advanced by the recent identification of relatively specific lymphatic endothelium markers, including Prox-1, VEGFR3, podoplanin and LYVE-1. The use of lymphatic markers has led to the observation that, contrary to previous assumptions, human lymphatic vessels extend deep inside the pulmonary lobule, either in association with bronchioles, intralobular arterioles or small pulmonary veins. Pulmonary lymphatic vessels may thus be classified into pleural, interlobular (in interlobular septa) and intralobular...
April 18, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29679604/outdoor-play-and-nature-connectedness-as-potential-correlates-of-internalized-mental-health-symptoms-among-canadian-adolescents
#3
Caroline Piccininni, Valerie Michaelson, Ian Janssen, William Pickett
Exposures to outdoor environments have great potential to be protective factors for the mental health of young people. In a national analysis of Canadian adolescents, we explored how such exposures, as well as self-perceptions of connectedness with nature, each related to the prevalence of recurrent psychosomatic symptoms. The data source for this cross-sectional study, consisting of a weighted sample of 29,784 students aged 11-15 years from 377 schools, was the 2013/2014 cycle of the Health Behaviour in School-aged Children (HBSC) study...
April 18, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29679560/developmental-origin-and-morphogenesis-of-the-diaphragm-an-essential-mammalian-muscle
#4
Elizabeth M Sefton, Mirialys Gallardo, Gabrielle Kardon
The diaphragm is a mammalian skeletal muscle essential for respiration and for separating the thoracic and abdominal cavities. Development of the diaphragm requires the coordinated development of muscle, muscle connective tissue, tendon, nerves, and vasculature that derive from different embryonic sources. However, defects in diaphragm development are common and the cause of an often deadly birth defect, Congenital Diaphragmatic Hernia (CDH). Here we comprehensively describe the normal developmental origin and complex spatial-temporal relationship between the different developing tissues to form a functional diaphragm using a developmental series of mouse embryos genetically and immunofluorescently labeled and analyzed in whole mount...
April 18, 2018: Developmental Biology
https://www.readbyqxmd.com/read/29679418/family-involvement-in-rehabilitation-coronary-artery-disease-patients-perspectives
#5
Sonja Tuomisto, Meeri Koivula, Päivi Åstedt-Kurki, Mika Helminen
AIMS AND OBJECTIVES: The aim of this paper is to describe CAD -patients' perceptions of family involvement in rehabilitation and the connection between background factors and family involvement. BACKGROUND: CAD-patients hospital stays can be very concise. Family members can support rehabilitation, but many challenges can emerge. There is a need to nurture patients and family members in an individual way and to recognize their concerns. More accurate patient education should be available for patients and their family members...
April 21, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29679401/translational-regulation-of-ribosomal-protein-s15-drives-characteristic-patterns-of-protein-mrna-epistasis
#6
Saurav Mallik, Sudipto Basu, Suman Hait, Sudip Kundu
Do coding and regulatory segments of a gene co-evolve with each-other? Seeking answers to this question, here we analyze the case of Escherichia coli ribosomal protein S15, that represses its own translation by specifically binding its messenger RNA (rpsO mRNA) and stabilizing a pseudoknot structure at the upstream untranslated region, thus trapping the ribosome into an incomplete translation initiation complex. In the absence of S15, ribosomal protein S1 recognizes rpsO and promotes translation by melting this very pseudoknot...
April 21, 2018: Proteins
https://www.readbyqxmd.com/read/29679293/cognates-interfere-with-language-selection-but-enhance-monitoring-in-connected-speech
#7
Chuchu Li, Tamar H Gollan
The current study investigated the contribution of phonology to bilingual language control in connected speech. Speech production was elicited by asking Mandarin-English bilinguals to read aloud paragraphs either in Chinese or English, while six words were switched to the other language in each paragraph. The switch words were either cognates or noncognates, and switching difficulty was measured by production of cross-language intrusion errors on the switch words (e.g., mistakenly saying (qiao3-ke4-li4) instead of chocolate)...
April 20, 2018: Memory & Cognition
https://www.readbyqxmd.com/read/29679187/growth-a-journey-from-experience-to-higher-perception-among-iranian-muslim-cpr-survivors
#8
Seyed Hamid Seyed Bagheri, Masoud Rayyani, Sedigheh Iranmanesh, Mahlagha Dehghan, Batool Tirgari, Seyed Habibollah Hosseini
Several studies have been conducted among cardiopulmonary resuscitation (CPR) survivors. Some studies have shown that positive and negative experiences coexist. Emotional distress and psychopathology in CPR survivors are related to the urgent need to make growth. Understanding the meaning of CPR survivors' lived experiences of growth may facilitate their growth. The aim of the study was to illuminate the meaning of CPR survivor's lived experiences of growth in southeast Iran. A qualitative design using a phenomenological hermeneutic approach influenced by Ricoeur was used in 12 CPR survivors...
April 20, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29679149/totally-endoscopic-implant-to-effect-a-gastric-bypass-12-month-safety-and-efficacy-outcomes
#9
Bryan J Sandler, Laurent Biertho, Mehran Anvari, Roberto Rumbaut, Luis Alonso Morales-Garza, Gustavo Torres-Barrera, Simon Marceau, Dennis Hong, C Daniel Smith, Santiago Horgan
BACKGROUND: Only a small percentage of candidates for bariatric surgery ever undergo a procedure for weight loss. Devices duplicating key effects of bariatric surgeries with removable, fully trans-oral implants could extend their benefits to patients unwilling to undergo anatomy-altering abdominal surgeries. METHODS: Thirty-two obese subjects (mean BMI: 42.3) were enrolled in a prospective, multicenter, single-arm, feasibility trial of the first fully trans-oral endoscopic gastrointestinal bypass device...
April 20, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29679142/conflict-modification-predictable-production-of-congruent-situations-facilitates-responding-in-a-stroop-task
#10
Constantin Schmidts, Anna Foerster, Wilfried Kunde
Humans cope with cognitive conflict in various ways, such as focusing on task-relevant instead of task-irrelevant information or avoiding situations where conflict is likely. These adaptations to conflict resemble those used to cope with negative affect. We examined whether situation modification, a strategy derived from the extended process model of emotion regulation, may influence responding in cognitive conflict tasks. This should be evident by a facilitation of actions that consistently modify situations towards congruent (positive) situations rather than to incongruent (negative) situations...
April 20, 2018: Psychological Research
https://www.readbyqxmd.com/read/29679120/regulation-of-hydrolytic-enzyme-activity-in-aquatic-microbial-communities-hosted-by-carnivorous-pitcher-plants
#11
Erica B Young, Jessica Sielicki, Jacob J Grothjan
Carnivorous pitcher plants Sarracenia purpurea host diverse eukaryotic and bacterial communities which aid in insect prey digestion, but little is known about the functional processes mediated by the microbial communities. This study aimed to connect pitcher community diversity with functional nutrient transformation processes, identifying bacterial taxa, and measuring regulation of hydrolytic enzyme activity in response to prey and alternative nutrient sources. Genetic analysis identified diverse bacterial taxa known to produce hydrolytic enzyme activities...
April 20, 2018: Microbial Ecology
https://www.readbyqxmd.com/read/29679095/implication-of-the-vrk1-chromatin-kinase-in-the-signaling-responses-to-dna-damage-a-therapeutic-target
#12
REVIEW
Ignacio Campillo-Marcos, Pedro A Lazo
DNA damage causes a local distortion of chromatin that triggers the sequential processes that participate in specific DNA repair mechanisms. This initiation of the repair response requires the involvement of a protein whose activity can be regulated by histones. Kinases are candidates to regulate and coordinate the connection between a locally altered chromatin and the response initiating signals that lead to identification of the type of lesion and the sequential steps required in specific DNA damage responses (DDR)...
April 20, 2018: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/29679022/biological-recognition-of-graphene-nanoflakes
#13
V Castagnola, W Zhao, L Boselli, M C Lo Giudice, F Meder, E Polo, K R Paton, C Backes, J N Coleman, K A Dawson
The systematic study of nanoparticle-biological interactions requires particles to be reproducibly dispersed in relevant fluids along with further development in the identification of biologically relevant structural details at the materials-biology interface. Here, we develop a biocompatible long-term colloidally stable water dispersion of few-layered graphene nanoflakes in the biological exposure medium in which it will be studied. We also report the study of the orientation and functionality of key proteins of interest in the biolayer (corona) that are believed to mediate most of the early biological interactions...
April 20, 2018: Nature Communications
https://www.readbyqxmd.com/read/29678948/an-rnai-screen-identifies-new-genes-required-for-normal-morphogenesis-of-larval-chordotonal-organs
#14
Abeer Hassan, Yael Timerman, Rana Hamdan, Nitzan Sela, Adel Avetisyan, Naomi Halachmi, Adi Salzberg
The proprioceptive chordotonal organs (ChO) of a fly larva respond to mechanical stimuli generated by muscle contractions and consequent deformations of the cuticle. The ability of the ChO to sense the relative displacement of its epidermal attachment sites likely depends on the correct mechanical properties of the accessory (cap and ligament) and attachment cells that connect the sensory unit (neuron and scolopale cell) to the cuticle. The genetic programs dictating the development of ChO cells with unique morphologies and mechanical properties are largely unknown...
April 20, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29678937/identification-of-a-specific-functional-network-altered-in-poststroke-cognitive-impairment
#15
Clément Bournonville, Hilde Hénon, Thibaut Dondaine, Christine Delmaire, Stephanie Bombois, Anne-Marie Mendyk, Charlotte Cordonnier, Solène Moulin, Xavier Leclerc, Régis Bordet, Renaud Lopes
OBJECTIVE: To study the association between poststroke cognitive impairment and defining a specific resting functional marker. METHODS: The resting-state functional connectivity 6 months after an ischemic stroke in 56 patients was investigated. Twenty-nine of the patients who had an impairment of one or several cognitive domains were compared to 27 without any cognitive deficit. We studied the whole-brain connectivity using 2 complementary approaches: graph theory to study the functional network organization and network-based statistics to explore connectivity between brain regions...
April 20, 2018: Neurology
https://www.readbyqxmd.com/read/29678921/a-repeating-sulfated-galactan-motif-resuscitates-dormant-micrococcus-luteus
#16
Thomas Böttcher, Dávid Szamosvári, Jon Clardy
Only a small fraction of bacteria can autonomously initiate growth on agar plates. Non-growing bacteria typically enter a metabolically inactive dormant state and require specific chemical trigger factors or signals to exit this state and resume growth. Micrococcus luteus has become a model organism for this important yet poorly understood phenomenon. So far, only few resuscitation signals have been described and all of them are produced endogenously by bacterial species. We report the discovery of a novel type of resuscitation signal that allows M...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29678919/investigating-the-central-metabolism-of-clostridium-thermosuccinogenes
#17
Jeroen Girwar Koendjbiharie, Kilian Wiersma, Richard van Kranenburg
Clostridium thermosuccinogenes is a thermophilic anaerobic bacterium able to convert various carbohydrates to succinate and acetate as main fermentation products. Genomes of the four publicly available strains have been sequenced and the genome of the type-strain has been closed. The annotated genomes were used to reconstruct the central metabolism, and enzyme assays were used to validate annotations and to determine co-factor specificity. Genes for the pathways to all fermentation products were identified, as well as for the Embden-Meyerhof-Parnas pathway, and the pentose phosphate pathway...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29678815/feedback-between-tissue-packing-and-neurogenesis-in-the-zebrafish-neural-tube
#18
Tom W Hiscock, Joel B Miesfeld, Kishore R Mosaliganti, Brian A Link, Sean G Megason
Balancing the rate of differentiation and proliferation in developing tissues is essential to produce organs of robust size and composition. Whilst many molecular regulators have been established, how these connect to physical and geometrical aspects of tissue architecture is poorly understood. Here, using high-resolution timelapse imaging, we find that changes to cell geometry associated with dense tissue packing play a significant role in regulating differentiation rate in the zebrafish neural tube. Specifically, progenitors that are displaced away from the apical surface due to crowding tend to differentiate, in a Notch-dependent manner...
April 20, 2018: Development
https://www.readbyqxmd.com/read/29678776/comparison-of-the-3d-structures-of-mouse-and-human-%C3%AE-synuclein-fibrils-by-solid-state-nmr-and-stem
#19
Songhwan Hwang, Pascal Fricke, Maximilian Zinke, Karin Giller, Joseph S Wall, Dietmar Riedel, Stefan Becker, Adam Lange
Intra-neuronal aggregation of α-synuclein into fibrils is the molecular basis for α -synucleinopathies, such as Parkinson's disease. The atomic structure of human α -synuclein (hAS) fibrils was recently determined by Tuttle et al. using solid-state NMR (ssNMR). The previous study found that hAS fibrils are composed of a single protofilament. Here, we have investigated the structure of mouse α -synuclein (mAS) fibrils by STEM and isotope-dilution ssNMR experiments. We found that in contrast to hAS, mAS fibrils consist of two or even three protofilaments which are connected by rather weak interactions in between them...
April 17, 2018: Journal of Structural Biology
https://www.readbyqxmd.com/read/29678734/polymeric-micelle-mediated-delivery-of-half-sandwich-ruthenium-ii-complexes-with-phosphanes-derived-from-fluoroloquinolones-for-lung-adenocarcinoma-treatment
#20
Przemysław Kołoczek, Agnieszka Skórska-Stania, Agnieszka Cierniak, Victor Sebastian, Urszula K Komarnicka, Michał Płotek, Agnieszka Kyzioł
Novel half-sandwich ruthenium(II) complexes with aminomethyl(diphenyl)phosphine derived from fluoroloquinolones (RuPCp, RuPSf, RuPLm, RuPNr) were being investigated as alternatives to well-established metal-based chemotherapeutics. All compounds were characterized by elemental analysis, selected spectroscopic methods (i.e., absorption and fluorescence spectroscopy, ESI-MS, NMR, circular dichroizm), X-ray diffractometry, ICP-MS, and electrochemical techniques. To overcome low solubility, serious side effects connected with systemic cytotoxicity of ruthenium complexes, and acquiring the resistance of cancer cells, polymeric nanoformulations based on Pluronic P-123 micelles loaded with selected Ru(II) complexes were prepared and characterized...
April 17, 2018: European Journal of Pharmaceutics and Biopharmaceutics
keyword
keyword
10380
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"