Thyroid transgender testosterone

BACKGROUND: Individuals whose gender identity differs from the biological sex and the social norms are defined as transgender. Sometimes transgender undergo gender affirming hormone therapy, which lasts for the entire life making essential to evaluate its potential long-term effects. Moreover, transgender can represent a susceptible sub-group of population and specific attention is needed in risk assessment, including the development of targeted animal models. Aim of the study is the implementation of a rodent demasculinizing-feminizing model through the setting of appropriate dose of hormone therapy and the selection of specific biomarkers to evaluate the sex transition...

CONTEXT: There is paucity of scientific data from India on gender identity disorders (GIDs) or gender dysphoria (GD). AIMS: To study the clinical, biochemical profile, personality characteristics and family support of GID subjects. SETTINGS AND DESIGN: A retrospective and cross-sectional study at an endocrine referral center in Kolkata in Eastern India between 2010 and 2015. SUBJECTS AND METHODS: Seventy-three GID subjects who presented to the center were included in the study...