Carter McInnis, María José Solana Garcia, Elysa Widjaja, Helena Frndova, Judith Van Huyse, Anne-Marie Guerguerian, Adeoye Oyefiade, Suzanne Laughlin, Charles Raybaud, Elka Miller, Keng Tay, Erin D Bigler, Maureen Dennis, Douglas Fraser, Craig Campbell, Karen Choong, Sonny Danani, Jacques Lacroix, Catherine Farrell, Miriam Helen Beauchamp, Russell Schachar, James S Hutchison, Anne Wheeler
The identification of children with traumatic brain injury (TBI) who are at risk of death or poor global neurological functional outcome remains a challenge. Magnetic resonance imaging (MRI) can detect several brain pathologies that are a result of TBI, however, the types and locations of pathology that are the most predictive remain to be determined. Forty-two critically ill children with TBI were prospectively recruited from pediatric intensive care units at five Canadian children's hospitals. Pathologies detected on subacute phase MRIs including cerebral hematoma, herniation, cerebral laceration, cerebral edema, midline shift, and the presence and location of cerebral contusion or diffuse axonal injury (DAI) in 28 regions of interest were assessed...
March 31, 2021: Journal of Neurotrauma