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Cardiac resynchronisation

Sérgio Barra, Rui Providência, Serge Boveda, Rudolf Duehmke, Kumar Narayanan, Anthony W Chow, Olivier Piot, Didier Klug, Pascal Defaye, Daniel Gras, Jean-Claude Deharo, Paul Milliez, Antoine Da Costa, Pierre Mondoly, Jorge Gonzalez-Panizo, Christophe Leclercq, Patrick Heck, Munmohan Virdee, Nicolas Sadoul, Jean-Yves Le Heuzey, Eloi Marijon
OBJECTIVE: In patients indicated for cardiac resynchronisation therapy (CRT), the choice between a CRT-pacemaker (CRT-P) versus defibrillator (CRT-D) remains controversial and indications in this setting have not been well delineated. Apart from inappropriate therapies, which are inherent to the presence of a defibrillator, whether adding defibrillator to CRT in the primary prevention setting impacts risk of other acute and late device-related complications has not been well studied and may bear relevance for device selection...
March 14, 2018: Heart: Official Journal of the British Cardiac Society
Lidija Poposka, Vladimir Boskov, Dejan Risteski, Jane Taleski, Filip Janusevski, Elizabeta Srbinovska, Ljubica Georgievska-Ismail
INTRODUCTION: Although strict selection criteria are used to select patients for cardiac resynchronisation therapy, up to 30% of patients do not have a positive clinical response. PATIENTS: A total of 102 consecutive patients who had biventricular pacemaker/defibrillator (CRT-P or CRT-D) implanted were enrolled in this prospective observational study. RESULTS: During the average follow-up period of 24.3 months 5 patients died and 17 (16.7%) patients were hospitalised with the symptoms of heart failure; 75 (73...
February 15, 2018: Open Access Macedonian Journal of Medical Sciences
Kenneth Dickstein, Camilla Normand, Angelo Auricchio, Nigussie Bogale, John G Cleland, Anselm K Gitt, Christoph Stellbrink, Stefan D Anker, Gerasimos Filippatos, Maurizio Gasparini, Gerhard Hindricks, Carina Blomström Lundqvist, Piotr Ponikowski, Frank Ruschitzka, Giovanni Luca Botto, Alan Bulava, Gabor Duray, Carsten Israel, Christophe Leclercq, Peter Margitfalvi, Óscar Cano, Chris Plummer, Nedim Umutay Sarigul, Maciej Sterlinski, Cecilia Linde
BACKGROUND: Cardiac resynchronisation therapy (CRT) reduces morbidity and mortality in appropriately selected patients with heart failure and is strongly recommended for such patients by guidelines. A European Society of Cardiology (ESC) CRT survey conducted in 2008-2009 showed considerable variation in guideline adherence and large individual, national and regional differences in patient selection, implantation practice and follow-up. Accordingly, two ESC associations, the European Heart Rhythm Association and the Heart Failure Association, designed a second prospective survey to describe contemporary clinical practice regarding CRT...
February 19, 2018: European Journal of Heart Failure
Serge Boveda, Radoslaw Lenarczyk, Stefano Fumagalli, Roland Tilz, Kinga Goscinska-Bis, Maciej Kempa, Pascal Defaye, Christelle Marquié, Alessandro Capucci, Laura Ueberham, Nikolaos Dagres
The purpose of this European Heart Rhythm Association (EHRA) prospective snapshot survey is to provide an overview of the factors influencing patient selection for the implantation of a particular type of device: subcutaneous implantable cardioverter-defibrillator (S-ICD) or transvenous implantable cardioverter-defibrillator (TV-ICD), across a broad range of tertiary European centres. A specially designed electronic questionnaire was sent via the internet to tertiary reference centres routinely implanting both TV-ICDs and S-ICDs...
February 8, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Khang-Li Looi, Karishma Sidhu, Lisa Cooper, Liane Dawson, Debbie Slipper, Andrew Gavin, Nigel Lever
Objective: Women have been under-represented in randomised clinical trials for primary prevention implantable cardioverter defibrillators (ICDs), and there are concerns about the efficacy of devices between genders. Our study aimed to investigate gender differences in the use of primary prevention ICD in patients with heart failure from the northern region of New Zealand. Methods: Patients with heart failure with systolic dysfunction who received primary prevention ICD/cardiac resynchronisation therapy-defibrillator (CRT-D) in the northern region of New Zealand from 1 January 2007 to 1 June 2015 were included...
2018: Heart Asia
Gustavo Lima da Silva, João de Sousa, Pedro Marques
Persistence of the left superior vena cava occurs in about 0.3-0.7% of the general population. It is of particular importance in patients who need cardiac resynchronisation therapy. We present a unique case in which a snare system and tunnelling tool were used to place the left ventricular lead in a patient with persistence of the left superior vena cava.
February 1, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Panagiota Anna Chousou, Peter J Pugh
No abstract text is available yet for this article.
December 7, 2017: Heart: Official Journal of the British Cardiac Society
Olivier Barthez
A fifth of patients with heart failure suffer from conduction disorders. A prolonged QRS duration on the electrocardiogram is an indicator of cardiac dyssynchrony. Several studies have shown the efficacy of cardiac resynchronisation therapy (CRT) in patients with a wide QRS duration: CRT is associated with reduced morbidity and mortality. An overview of the methods of implantation of CRT devices, the results of this electrical treatment and its limits.
November 2017: Soins; la Revue de Référence Infirmière
Matthew Sinclair, Devis Peressutti, Esther Puyol-Antón, Wenjia Bai, Simone Rivolo, Jessica Webb, Simon Claridge, Thomas Jackson, David Nordsletten, Myrianthi Hadjicharalambous, Eric Kerfoot, Christopher A Rinaldi, Daniel Rueckert, Andrew P King
Abnormal cardiac motion can indicate different forms of disease, which can manifest at different spatial scales in the myocardium. Many studies have sought to characterise particular motion abnormalities associated with specific diseases, and to utilise motion information to improve diagnoses. However, the importance of spatial scale in the analysis of cardiac deformation has not been extensively investigated. We build on recent work on the analysis of myocardial strains at different spatial scales using a cardiac motion atlas to find the optimal scales for estimating different cardiac biomarkers...
January 2018: Medical Image Analysis
Juliana Kanawati, Raymond W Sy
Cardiac resynchronisation therapy (CRT) is a cornerstone in the contemporary management of heart failure. The most effective way of predicting response to this therapy remains electrocardiographic (ECG) criteria of electromechanical dyssynchrony. The left bundle branch block (LBBB) pattern is currently the most robust ECG criterion in predicting improvement in symptoms and reduction in mortality. However, recent studies using three-dimensional (3D) mapping and cardiac magnetic resonance imaging (CMR) have demonstrated heterogeneous left ventricular activation patterns in patients with LBBB...
October 6, 2017: Heart, Lung & Circulation
Stanislaw Morawski, Patrycja Pruszkowska, Beata Sredniawa, Radoslaw Lenarczyk, Zbigniew Kalarus
PURPOSE: Radiofrequency catheter ablation (RFCA) for electrical storm (ES) has become a widely used therapeutic method. Its effectiveness in comparison to other forms of ES treatment is however uncertain. METHODS: This single-centre retrospective study investigated the long-term clinical outcome after RFCA for ES and compared long-time effects of ablation to other forms of treatment. The study population consisted of 70 consecutive patients hospitalised between January 2010 and June 2015 due to ES...
December 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Paweł Ptaszyński, Marcin Grabowski, Oskar Kowalski, Maciej Kempa, Przemysław Mitkowski, Andrzej Przybylski, Maciej Sterliński
In the past years, cardiovascular mortality has decreased but despite these cardiovascular diseases are responsible for millions of deaths every year in the world and approximately 25% of which are sudden cardiac death (SCD). Implantable defibrillators (ICD) is proven therapy used in primary and secondary SCD prevention. Currently majority of devices use transvenous leads inserted predominantly into the right heart for both pacing and defibrillation. On the other hand, ICD may cause complica-tions, including inappropriate shocks, device-related infection and lead failure...
2017: Kardiologia Polska
Kaushik Guha, Jens Spießhöfer, Adam Hartley, Simon Pearse, Philip Y Xiu, Rakesh Sharma
PURPOSE: To determine the prognostic implications of changes towards hyponatremia at varying time-points in the treatment of patients undergoing cardiac resynchronisation therapy (CRT). METHODS: A retrospective series of 249 patients was studied from 2002 to 2013. The population was categorized on the basis of serum sodium profile at baseline, at 1 month and at 6 month follow up visits following successful CRT implantation. The composite endpoint was all-cause mortality and heart failure hospitalisation (defined by the need for intravenous diuretic therapy) following CRT implantation...
September 2017: Indian Heart Journal
Michal Kerekanič, Marek Hudák, Silvia Mišíková, Erika Komanová, Alexander Bohó, Ján Kyselovič, Branislav Stančák
BACKGROUND: Cardiac troponin I (cTnI) is a valuable prognostic biomarker in patients with chronic heart failure (CHF). However, the prognostic importance of cTnI in patients who received cardiac resynchronisation therapy (CRT) remains unknown. The aim of this prospective study was to determine the prognostic value of high-sensitive cTnI (hs-cTnI) in CHF patients receiving CRT. METHODS: We performed measurements of baseline hs-cTnI levels in CRT patients with ischaemic as well as nonischaemic aetiology of CHF, and we investigated their possible association with response to CRT and survival of patients...
October 12, 2017: Acta Cardiologica
Angelo Auricchio, François Regoli, Giulio Conte, Maria Luce Caputo
The implantation rate of cardiac electronic devices has grown over the past decades. The number of treated patients has increased in parallel with the complexity of the patient population treated, being older, frailer, having more complex devices (in particular, cardiac resynchronisation therapy) and presenting with a greater comorbidity burden. As a consequence, there is a rising number of related implanted system complications, including malfunction and infection. Thus, the demand for transvenous lead extraction (TLE) has also substantially increased...
August 2017: Arrhythmia & Electrophysiology Review
Simon Claridge, Frederic A Sebag, Steven Fearn, Jonathan M Behar, Bradley Porter, Tom Jackson, Benjamin Sieniewicz, Justin Gould, Jessica Webb, Zhong Chen, Mark O'Neill, Jaswinder Gill, Christophe Leclercq, Christopher A Rinaldi
OBJECTIVE: Responders to cardiac resynchronisation therapy whose device has a defibrillator component and who do not receive a therapy in the lifetime of the first generator have a very low incidence of appropriate therapy after box change. We investigated the cost implications of using a risk stratification tool at the time of generator change resulting in these patients being reimplanted with a resynchronisation pacemaker. METHODS: A decision tree was created using previously published data which had demonstrated an annualised appropriate defibrillator therapy risk of 2...
September 29, 2017: Heart: Official Journal of the British Cardiac Society
Praveen Rao, Mitchell Faddis
No abstract text is available yet for this article.
December 2017: Heart: Official Journal of the British Cardiac Society
P Demetriades, A Bell, C Gubran, H Marshall, J de Bono, L Hudsmith
BACKGROUND: Cardiac resynchronisation therapy (CRT) is a well-recognised treatment in systolic heart failure. There is limited evidence in congenital patients with univentricular hearts or systemic right ventricles. In 2014 PACES/HRS published a consensus statement recommending CRT if ventricular ejection fraction (EF)≤35%, QRS duration≥150ms (with RBBB in systemic RV), NYHA II-IV and ventricular dilatation. The incidence of patients meeting these criteria in whom CRT is possible is not known...
December 15, 2017: International Journal of Cardiology
Christopher J McAloon, Danish Ali, Thomas Hamborg, Prithwish Banerjee, Paul O'Hare, Harpal Randeva, Faizel Osman
OBJECTIVE: Cardiac resynchronisation therapy (CRT) is an effective therapy for selected patients with heart failure (HF); however, a significant non-response rate exists. We examined current evidence on extracellular cardiac matrix (ECM) biomarkers in predicting response following CRT. METHODS: Complete literature review of PubMed, Ovid SP MEDLINE, Cochrane Library and TRIP, reference lists, international cardiology conferences and ongoing studies between December 1999 and December 2015 conducted according to prospectively registered study selection and analysis criteria (PROSPERO:CRD42016025864) was performed...
2017: Open Heart
Haipeng Tang, Shaojie Tang, Weihua Zhou
Cardiac resynchronisation therapy (CRT) is a standard treatment for patients with heart failure; however, the low response rate significantly reduces its cost-effectiveness. A favourable CRT response primarily depends on whether implanters can identify the optimal left ventricular (LV) lead position and accurately place the lead at the recommended site. Myocardial imaging techniques, including echocardiography, cardiac magnetic resonance imaging and nuclear imaging, have been used to assess LV myocardial viability and mechanical dyssynchrony, and deduce the optimal LV lead position...
June 2017: Arrhythmia & Electrophysiology Review
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