keyword
https://read.qxmd.com/read/21437827/management-and-prevention-of-pelvic-adhesions
#21
REVIEW
Sheikha Al-Jabri, Togas Tulandi
Postsurgical adhesion formation is an important clinical problem within all surgical specialties. In gynecology, adhesions resulting from gynecologic procedures are a major clinical, social, and economic concern because they may result in pelvic pain, infertility, or bowel obstruction. In addition, it may lead to additional surgery to resolve the adhesion-related complications. This review evaluates the available evidence regarding the effectiveness of various strategies for reducing postsurgical adhesions...
March 2011: Seminars in Reproductive Medicine
https://read.qxmd.com/read/20853233/adipose-tissue-engineering-from-adult-human-stem-cells-a-new-concept-in-biosurgery
#22
JOURNAL ARTICLE
Jeffrey M Ahn, Jeremy J Mao
Current autologous fat grafting technique suffers from the drawbacks of donor site morbidity and, more importantly, significant resorption of the grafted fat. Adipose tissue engineering using adult human stem cells has been found to overcome the shortcomings of autologous fat grafting in reconstructing facial defects. Mesenchymal stem cells that can self-renew and differentiate into mature adipocytes have been used to generate adipose tissue, in both in vitro and in vivo cell transplantation studies. However, long-term maintenance of the shape and dimension of the produced adipose tissue remains a challenge, even in tissue engineering with cell transplantation...
October 2010: Facial Plastic Surgery: FPS
https://read.qxmd.com/read/20637345/preventing-intraperitoneal-adhesions-with-atorvastatin-and-sodium-hyaluronate-carboxymethylcellulose-a-comparative-study-in-rats
#23
COMPARATIVE STUDY
Miltiadis A Lalountas, Konstantinos D Ballas, Christos Skouras, Christos Asteriou, Theodoros Kontoulis, Dimitrios Pissas, Apostolos Triantafyllou, Athanasios K Sakantamis
OBJECTIVES: The aim of this study was to compare the effectiveness of atorvastatin with the sodium hyaluronate/carboxymethylcellulose (HA/CMC, Seprafilm; Genzyme; Genzyme Biosurgery Corporation, Cambridge, MA) in preventing postoperative intraperitoneal adhesion formation in rats. METHODS: Sixty Wistar rats underwent a laparotomy, and adhesions A were induced by cecal abrasion. The animals were divided into 4 groups: group 1, control A; group 2, (A + atorvastatin); group 3, (A + HA/CMC), and group 4, (A + atorvastatin + HA/CMC)...
July 2010: American Journal of Surgery
https://read.qxmd.com/read/20397818/biomedical-applications-of-photochemistry
#24
REVIEW
Barbara Pui Chan
Photochemistry is the study of photochemical reactions between light and molecules. Recently, there have been increasing interests in using photochemical reactions in the fields of biomaterials and tissue engineering. This work revisits the components and mechanisms of photochemistry and reviews biomedical applications of photochemistry in various disciplines, including oncology, molecular biology, and biosurgery, with particular emphasis on tissue engineering. Finally, potential toxicities and research opportunities in this field are discussed...
October 2010: Tissue Engineering. Part B, Reviews
https://read.qxmd.com/read/19891541/facial-reconstruction-by-biosurgery-cell-transplantation-versus-cell-homing
#25
REVIEW
Jeremy J Mao, Michael S Stosich, Eduardo K Moioli, Chang Hun Lee, Susan Y Fu, Barbara Bastian, Sidney B Eisig, Candice Zemnick, Jeffrey Ascherman, June Wu, Christine Rohde, Jeffrey Ahn
The face distinguishes one human being from another. When the face is disfigured because of trauma, tumor removal, congenital anomalies, or chronic diseases, the patient has a strong desire for functional and esthetic restoration. Current practice of facial reconstruction using autologous grafts, synthetic fillers, and prostheses is frequently below the surgeon's and patient's expectations. Facial reconstruction is yet to take advantage of recent advances in seemingly unrelated fields of stem cell biology, chemical engineering, biomaterials, and tissue engineering...
April 2010: Tissue Engineering. Part B, Reviews
https://read.qxmd.com/read/19272839/bioresorbable-film-for-the-prevention-of-adhesion-to-the-anterior-spine-after-anterolateral-discectomy
#26
JOURNAL ARTICLE
Lisa S Klopp, Jeffrey M Toth, William C Welch, Sangeeta Rao, Joseph W Tai, Kevin A Thomas, Simon Turner
BACKGROUND CONTEXT: The development of scar tissue and adhesions postoperatively is a natural consequence of healing but can be associated with medical complications and render reoperation difficult. Many biocompatible products have been evaluated as barriers or deterrents to adhesions. PURPOSE: To evaluate the efficacy of a bioresorbable polylactide film as a barrier to adhesion formation after anterolateral discectomy. STUDY DESIGN: Experimental study...
May 2009: Spine Journal: Official Journal of the North American Spine Society
https://read.qxmd.com/read/19076250/septic-injury-inducible-genes-in-medicinal-maggots-of-the-green-blow-fly-lucilia-sericata
#27
JOURNAL ARTICLE
B Altincicek, A Vilcinskas
Lucilia sericata maggots are used world-wide in biosurgery for the medical treatment of nonhealing wounds because they ingest necrotic tissues and significantly promote healing. To gain further insight into interdependencies between ecological adaptation and molecular evolution of innate immunity in Diptera, we used the suppression subtractive hybridization method to screen for genes that are differentially expressed in response to septic wounding of sterile second instar larvae of L. sericata. This approach resulted in the identification of 65 novel Lucilia genes including potential signalling proteins (e...
February 2009: Insect Molecular Biology
https://read.qxmd.com/read/18436596/selective-antimicrobial-activity-of-maggots-against-pathogenic-bacteria
#28
JOURNAL ARTICLE
Domen Jaklic, Ales Lapanje, Klemen Zupancic, Dragica Smrke, Nina Gunde-Cimerman
Maggot therapy, also known as biosurgery, is an ancient method for the healing of chronic infected wounds. Although clinicians have reported on the beneficial activities of the Lucilia sericata larvae that have been used for healing chronic wounds, the selectivity of this therapy against the different pathogenic micro-organisms that are found in chronic wounds has never been analysed. In the present study, we have investigated the in vitro activities of larval excreta/secreta both against selected bacterial strains that frequently occur in chronically infected wounds, and against bacteria isolated directly from the larvae and their excreta/secreta...
May 2008: Journal of Medical Microbiology
https://read.qxmd.com/read/17954307/mechanical-strength-and-stiffness-of-biodegradable-and-titanium-osteofixation-systems
#29
COMPARATIVE STUDY
Gerrit J Buijs, Eduard B van der Houwen, Boudewijn Stegenga, Rudulf R M Bos, Gijsbertus J Verkerke
PURPOSE: To present relevant mechanical data to simplify the selection of an osteofixation system for situations requiring immobilization in oral and maxillofacial surgery. MATERIALS AND METHODS: Seven biodegradable and 2 titanium osteofixation systems were investigated. The plates and screws were fixed to 2 polymethylmethacrylate (PMMA) blocks to simulate bone segments. The plates and screws were subjected to tensile, side bending, and torsion tests. During tensile tests, the strength of the osteofixation system was monitored...
November 2007: Journal of Oral and Maxillofacial Surgery
https://read.qxmd.com/read/17902020/intra-abdominal-use-of-taurolidine-or-heparin-as-alternative-products-to-an-antiadhesive-barrier-seprafilm-in-adhesion-prevention-an-experimental-study-on-mice
#30
COMPARATIVE STUDY
Isamettin Bahadir, Mustafa Oncel, Metin Kement, Yusuf Sahip
PURPOSE: Seprafilm (Genzyme Biosurgery, Cambridge, MA) remains a widely used product in postoperative adhesion prevention. This study was designed to compare the antiadhesive effects of taurolidine, heparin, and Seprafilm in a murine cecal abrasion model. METHODS: Sixty male Balb/c mice underwent a cecal abrasion procedure and were randomized into four groups (n = 15 in each). Groups T, H, and S animals intraperitoneally received taurolidine, heparin, and Seprafilm, respectively, and Group C animals were reserved as control...
December 2007: Diseases of the Colon and Rectum
https://read.qxmd.com/read/17551073/larval-therapy-from-antiquity-to-the-present-day-mechanisms-of-action-clinical-applications-and-future-potential
#31
REVIEW
Iain S Whitaker, Christopher Twine, Michael J Whitaker, Mathew Welck, Charles S Brown, Ahmed Shandall
When modern medicine fails, it is often useful to draw ideas from ancient treatments. The therapeutic use of fly larvae to debride necrotic tissue, also known as larval therapy, maggot debridement therapy or biosurgery, dates back to the beginnings of civilisation. Despite repeatedly falling out of favour largely because of patient intolerance to the treatment, the practice of larval therapy is increasing around the world because of its efficacy, safety and simplicity. Clinical indications for larval treatment are varied, but, in particular, are wounds infected with multidrug-resistant bacteria and the presence of significant co-morbidities precluding surgical intervention...
June 2007: Postgraduate Medical Journal
https://read.qxmd.com/read/17509269/postoperative-pericardial-adhesion-prevention-using-carbylan-sx-in-a-rabbit-model
#32
COMPARATIVE STUDY
Rafe C Connors, Jeffery J Muir, Yanchun Liu, G Russell Reiss, Peter C Kouretas, Matthew G Whitten, Tyler K Sorenson, Glenn D Prestwich, David A Bull
INTRODUCTION: The presence of dense adhesions within the pericardial space complicates reoperative cardiac surgery. Prior attempts to reduce adhesion formation after primary cardiac surgery using medications or biomaterials have had variable success. Carbylan-SX (Carbylan Biosurgery Inc., Palo Alto, CA) is a hyaluronan-based biomaterial, which has been shown to be effective at reducing adhesions in a nonthoracic rat model. This study evaluates whether Carbylan-SX can effectively reduce postoperative adhesions within the pericardial cavity...
June 15, 2007: Journal of Surgical Research
https://read.qxmd.com/read/17465800/bioactive-wound-healing-bioaesthetics-and-biosurgery-three-pillars-of-product-development-interview-with-geoff-mackay
#33
Geoff MacKay
Tissue regeneration specialist company Organogenesis Inc. was one of the first biotech companies formed. Incorporated in 1985, the company was originally a spin-off from a research program at MIT. For the first 10-15 years, Organogenesis was heavily research based, but then gradually moved into development. The company's flagship product is Apligraf--a living, bilayered skin construct with two FDA-approved indications: diabetic foot ulcers and venous leg ulcers. As Apligraf neared the market, it was necessary to 'graft' a manufacturing capability onto the company...
March 2006: Regenerative Medicine
https://read.qxmd.com/read/17416179/-an-efficient-method-for-managing-problem-wounds-maggot-therapy-in-biosurgery
#34
JOURNAL ARTICLE
André Glod
No abstract text is available yet for this article.
March 2007: Pflege Zeitschrift
https://read.qxmd.com/read/17157844/reduced-postoperative-intra-abdominal-adhesions-using-carbylan-sx-a-semisynthetic-glycosaminoglycan-hydrogel
#35
JOURNAL ARTICLE
Yanchun Liu, Xiao Zheng Shu, Glenn D Prestwich
OBJECTIVE: To compare the efficacy of crosslinked Carbylan-SX (Carbylan BioSurgery, Inc., Palo Alto, CA) hydrogel films and sprayable gels as physical barriers in reducing postoperative intra-abdominal adhesions in the rat cecum-abdominal wall and rat uterine horn models. DESIGN: Pre-formed crosslinked Carbylan-SX films and sprayable in situ crosslinkable Carbylan-SX gels were evaluated in rat cecum-abdominal wall and rat uterine horn models and compared with commercially available and clinically used Seprafilm...
April 2007: Fertility and Sterility
https://read.qxmd.com/read/17001561/-maggot-therapy-in-gynecology
#36
JOURNAL ARTICLE
D Brüggmann, H-R Tinneberg, M T Zygmunt
Ancient societies recognised beneficial effects of certain fly larvae on wound healing. Nowadays, biosurgery with living maggots has proven very useful in the therapy of infected, necrotic, acute and chronic wounds. The larvae cause a rapid and selective wound debridement, a disinfective effect and rapid formation of granulation tissue and epithelium. In our hospital, we gathered experience in wounds caused by gynecological surgery. Here, maggot therapy has been used in locations--e. g. perineal--which are difficult to provide with hydrocolloid wound dressings...
October 2006: Zentralblatt Für Gynäkologie
https://read.qxmd.com/read/16799376/clinical-approach-to-wounds-d%C3%A3-bridement-and-wound-bed-preparation-including-the-use-of-dressings-and-wound-healing-adjuvants
#37
REVIEW
Christopher E Attinger, Jeffrey E Janis, John Steinberg, Jaime Schwartz, Ali Al-Attar, Kara Couch
This is a clinical review of current techniques in wound bed preparation found to be effective in assisting the wound-healing process. The process begins with the identification of a correct diagnosis of the wound's etiology and continues with optimizing the patient's medical condition, including blood flow to the wound site. Débridement as the basis of most wound-healing strategies is then emphasized. Various débridement techniques, including surgery, topical agents, and biosurgery, are thoroughly discussed and illustrated...
June 2006: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/16319566/effects-of-intra-articular-hylan-g-f-20-injections-on-clinical-and-biomechanical-characteristics-of-the-knee-in-osteoarthritis
#38
JOURNAL ARTICLE
Güneş Yavuzer, Birkan Sonel, Nurben Süldür, Süreyya Ergin
The objectives of this study were to investigate the effects of Hylan G-F 20 (Synvisc; Genzyme Biosurgery, Ridgefield, New Jersey, USA) injections on clinical and biomechanical gait characteristics of patients with knee osteoarthritis. The design was a before-after trial, set in the gait laboratory of the rehabilitation unit of a university hospital. Twelve patients participated with an average age (+/-SD) of 63.2+/-4.4 years, and Kellgren and Lawrence grade II or III knee osteoarthritis. The main outcome measures were the Western Ontario McMaster Universities Osteoarthritis Index, and time-distance, kinematic and kinetic parameters of gait...
December 2005: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://read.qxmd.com/read/16084789/the-use-of-surgi-wrap-in-delayed-adjustable-strabismus-surgery
#39
JOURNAL ARTICLE
Ho-Kyung Choung, Jeong-Min Hwang
PURPOSE: To determine the effect of Surgi Wrap (MacroPore Biosurgery, Inc, San Diego, California, USA) in delayed adjustable strabismus surgery. DESIGN: An animal study. METHODS: A prospective, masked-observer, controlled study was performed in rabbits. Forty-eight eyes of 24 rabbits were divided into two groups. After recession of the superior rectus muscle (SRM), Surgi Wrap was applied beneath and over the SRM in the Surgi Wrap group, and no barrier was applied in the control group...
September 2005: American Journal of Ophthalmology
https://read.qxmd.com/read/15510315/laparoscopic-ventral-hernia-repair-advances-and-limitations
#40
REVIEW
Salvador Morales-Conde
Laparoscopic ventral hernia repair, a topic of great debate today, has evolved to be a feasible and safe procedure. It has been shown to be as effective as open repair, with a lower recurrence rate. Despite the excellent results of the laparoscopic repair of ventral hernias, numerous controversies are associated with this procedure, such us how to create the pneumoperitoneum, how to perform adhesiolysis, how to manage the hernia sac, the evolution and complications related to postoperative seroma, the type and size of the mesh, and how to insert and fix the mesh...
September 2004: Seminars in Laparoscopic Surgery
keyword
keyword
103718
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.