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Equine pericardium

Aisa Rassoli, Nasser Fatouraee, Robert Guidoin
The benefit of bioprosthetic aortic valve over mechanical valve replacements is the release of thromboembolism and digression of long-term anticoagulation treatment. The function of bioprostheses and their efficiency is known to depend on the mechanical properties of the leaflet tissue. So it is necessary to select a suitable tissue for the bioprosthesis. The purpose of the present study is to clarify the viscoelastic behavior of bovine, equine, and porcine pericardium. In this study, pericardiums were compared mechanically from the viscoelastic aspect...
March 30, 2018: Artificial Organs
Adrian Kolesar, Tomas Toporcer, Milan Bajmoczi, Jan Luczy, Peter Candik, Frantisek Sabol
BACKGROUND: The unicuspid aortic valve (UAV) is a well-described pediatric congenital abnormality, with incidence of 0.02% in the general population. Bicuspidization has been described as a potential surgical option to repair this defect. METHODS: Seventeen symptomatic young patients with a unicuspid valve combined with either valve insufficiency or valve stenosis underwent aortic valve (AV) bicuspidization procedure by using an equine pericardium. In addition to bicuspidization, 8 patients underwent aortic ring implantation and 5 patients underwent supracoronary replacement of the aorta...
May 2018: Annals of Thoracic Surgery
Konstantinos Droutsas, Dimitrios Papaconstantinou, Ilias Georgalas, Georgios Kymionis, Konstantinos Andreanos, Elli Stamou, Nikolaos Mamas
PURPOSE: To describe the use of equine pericardium as an off-label temporary emergency treatment of scleral and corneal perforations. METHODS: Three eyes of two male patients aged 34 and 38 years were included, i.e. a case with a history of severe bilateral thermal burn undergoing phacoemulsification complicated by tearing of the main port causing iris exposure and a patient with bilateral corneal perforation secondary to non-infectious corneal melt due to presumed ocular non-steroid anti-inflammatory drug abuse...
December 19, 2017: International Ophthalmology
Oleg Fedevych, Oleksandr Yachnik, Yaroslav Mykychak, Yaroslav Ivanov, Olga Borodinova, Illya Yemets
A neonate with antenatally diagnosed severe aortic valve stenosis, left ventricular outflow tract obstruction, left ventricular endocardial fibroelastosis, and severe mixed mitral valve disease was admitted to our center for balloon aortic valvuloplasty. On day 49, we performed a Ross-Konno procedure and mitral valve replacement on the baby, whose weight was 3.4 kg. Right ventricle-to-pulmonary artery continuity was restored with a handmade trileaflet Gore-Tex conduit. We used a handmade cylindrical prosthesis made from decellularized equine pericardium in the mitral position...
January 1, 2017: World Journal for Pediatric & Congenital Heart Surgery
Keti Vitanova, Julie Cleuziou, Jelena Pabst von Ohain, Melchior Burri, Andreas Eicken, Rüdiger Lange
BACKGROUND: The development of recoarctation after the Norwood I procedure is a known complication in patients with hypoplastic left heart syndrome (HLHS). METHODS: We reviewed data on 194 consecutive patients with HLHS who underwent the Norwood I procedure between 2000 and 2015. All patients who survived until the second stage of the procedure were included. Recoarctation was defined by the need for intervention, either catheter based or surgical. The aim of our study was to determine if the patch material used for the initial arch reconstruction had an influence on the development of recoarctation...
February 2017: Annals of Thoracic Surgery
Gabriele Di Giammarco, Daniele Marinelli, Massimiliano Foschi, Michele Di Mauro
Tricuspid valve (TV) endocarditis is a common complication in intravenous drug addicts. In case of TV replacement, the main issue is the high risk of new endocarditis on TV prosthesis. On November 2014, a 44 year-old male patient with a history of intravenous drug addiction was referred for TV endocarditis owing to Staphylococcus aureus and severe regurgitation complicated by pulmonary embolism and heart failure. Preoperative echocardiography showed a large vegetation of the anterior leaflet (1.95 × 0.92 cm) covering a huge hole in the leaflet itself...
July 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Eliran Moshe Reuven, Shani Leviatan Ben-Arye, Tal Marshanski, Michael E Breimer, Hai Yu, Imen Fellah-Hebia, Jean-Christian Roussel, Cristina Costa, Manuel Galiñanes, Rafael Mañez, Thierry Le Tourneau, Jean-Paul Soulillou, Emanuele Cozzi, Xi Chen, Vered Padler-Karavani
BACKGROUND: The two common sialic acids (Sias) in mammals are N-acetylneuraminic acid (Neu5Ac) and its hydroxylated form N-glycolylneuraminic acid (Neu5Gc). Unlike most mammals, humans cannot synthesize Neu5Gc that is considered foreign and recognized by circulating antibodies. Thus, Neu5Gc is a potential xenogenic carbohydrate antigen in bioprosthetic heart valves (BHV) that tend to deteriorate in time within human patients. METHODS: We investigated Neu5Gc expression in non-engineered animal-derived cardiac tissues and in clinically used commercial BHV, and evaluated Neu5Gc immunogenicity on BHV through recognition by human anti-Neu5Gc IgG...
September 2016: Xenotransplantation
A Jiménez-Martín, F J Santos-Yubero, F J Najarro-Cid, S Navarro-Martínez, M Zurera-Carmona, S Pérez-Hidalgo
INTRODUCTION AND OBJECTIVES: Rotator cuff re-ruptures appear in 38-65% of cases. In order to reduce this rate, many studies have been performed using different types of biomaterial for purely mechanical aims (re-inforce the suture) and/or biological agents (growth factor transporterts). The aim of this study is to review 22 cases treated with xenografts and analyse various current alternatives. MATERIALS AND METHODS: A descriptive and retrospective study was conducted using the variables of age, sex, laterality, time of surgery, involvement in MRI, number of anchors, and final mobility results on the Constant and the University of California Los Angeles (UCLA) validated scales...
September 2016: Revista Española de Cirugía Ortopédica y Traumatología
Roberto Centonze, Emiliano Agostini, Samantha Massaccesi, Stefano Toninelli, Letterio Morabito
BACKGROUND: A large variety of biological and artificial materials are employed in dural repair, each of them with major limitations. Autologous grafts have limited availability and require an additional incision and surgical time. Cadaveric preparations and heterologous materials entail the risk of iatrogenic transmission of prions, whereas synthetic substitutes have been reported to cause inflammatory reactions and graft rejection. An equine-derived pericardium membrane has been developed (Heart(®), Bioteck, Vicenza, Italy) with mechanical and safety-related features that could make it suitable for neurosurgical application...
July 2016: Asian Journal of Neurosurgery
William Feng, Michael Coady
We report our experience with emergent treatment of ventricular rupture following a mitral valve replacement in a 90 year-old male. The repair was performed using a Tachosil patch (Baxter Health Care Corporation, Westlake Village, California), a fibrin sealant coated on an equine collagen sponge, and BioGlue (Cryolife, Kenneson, GA) and bovine pericardium (Edwards Lifesciences, Irvine, CA). Aside from early ventricular dysfunction requiring a low-dose dopamine infusion, this patient's recovery was uneventful...
June 2016: Annals of Thoracic Surgery
Riccardo Cusinato, Monia Pacenti, Thomas Martello, Paolo Fattori, Marco Morroni, Giorgio Palù
Bone grafting is a common procedure for bone reconstruction in dentistry, orthopedics, and neurosurgery. A wide range of grafts are currently used, and xenografts are regarded as an interesting alternative to autogenous bone because all mammals share the same bone mineral component composition and morphology. Antigens must be eliminated from bone grafts derived from animal tissues in order to make them biocompatible. Moreover, the processing method must also safely inactivate and/or remove viruses or other potential infectious agents...
June 2016: Journal of Virological Methods
Akimasa Morisaki, Yasuyuki Kato, Yosuke Takahashi, Toshihiko Shibata
Reoperation for paravalvular leakage can cause recurrent paravalvular leakage through severe damage to the mitral annulus. Previously, mitral valve replacement using a half-and-half technique for extensive mitral annular calcification was reported; here, application of the technique to treat recurrent paravalvular leakage is described. A 78-year-old male with three prior mitral valve replacements developed recurrent paravalvular leakage, for which he had undergone his third mitral valve replacement at the age of 69 years...
May 2015: Journal of Heart Valve Disease
Marialisa Nesta, Andrea Mazza, Gianluigi Perri, Piergiorgio Bruno, Massimo Massetti
We report a patient with situs inversus who developed a large posterior interventricular septum pseudoaneurysm with a septal defect following a myocardial infarction. The ventricular septum was approached through the left ventricle and the entrance of the pseudoaneurysm was repaired with a strip of equine pericardium.
March 2016: Journal of Cardiac Surgery
Tomoya Uchimuro, Toshihiro Fukui, Atsushi Shimizu, Shuichirou Takanashi
BACKGROUND: Mitral valve surgery in patients with severe mitral annular calcification can be challenging. We investigated surgical outcomes of mitral valve surgery with complete annular decalcification and reconstruction. METHODS: Between January 2004 and December 2013, 2,104 patients underwent mitral valve surgery at our institution. Of these, 61 patients (mean age 70 years) with severe mitral annular calcification were reviewed. Valve lesions were stenosis in 20 patients (32...
March 2016: Annals of Thoracic Surgery
Hiroshi Kubota, Hidehito Endo, Mio Noma, Hikaru Ishii, Hiroshi Tsuchiya, Akihiro Yoshimoto, Yu Takahashi, Yusuke Inaba, Yoshifumi Nishino, Masao Nunokawa, Yutaka Hosoi, Tooru Ikezoe, Masaru Nemoto, Yoshihisa Makino, Yoko Nemoto, Mitsuru Matsukura, Masanori Sugiyama, Nobutsugu Abe, Hirohisa Takeuchi, Gen Nagao, Eri Kondo, Osamu Yanagida, Hideaki Yoshino, Kenichi Sudo
BACKGROUND: Which graft material is the optimal graft material for the treatment of infected aortic aneurysms and aortic graft infections is still a matter of controversy. Orthotopic aortic reconstruction with intraoperatively prepared xenopericardial roll grafts without omentopexy was performed as the "initial" operation to treat aortic infection or as a "rescue" operation to treat graft infection. Mid-term outcomes were evaluated. METHODS: Between 2009 and 2013, orthotopic xenopericardial roll graft replacement was performed to treat eight patients (male/female: 6/2; mean age: 69...
2015: Journal of Cardiothoracic Surgery
Gerit Mulder, Daniel K Lee
Complex wounds frequently undergo surgical excision and grafting in an attempt to optimize the wound environment and to facilitate wound closure. Individuals who have not responded to conventional non-surgical therapies and dressings may not be good candidates for autologous grafting. A fully flexible, cross-linked, acellular equine pericardium biological xenograft was used to address difficult-to-treat and recalcitrant wounds of the lower extremity. Twenty-four complex wounds of varying etiology, including diabetic, venous, trauma, vasculitic, and post-surgical wounds underwent surgical debridement and xenograft application...
September 2009: Wounds: a Compendium of Clinical Research and Practice
Gerit Mulder, Daniel K Lee
A 39-year-old man with previously undiagnosed scleroderma was admitted to the UCSD Medical Center with bilateral, limb-threatening necrotic lower extremity ulcers extending to underlying fascia and muscle. Rather than amputate the extremities, the patient requested alternative treatment and underwent extensive tissue debridement followed by placement of an equine pericardium xenograft. Subsequent to treatment, the patient underwent weekly examinations and dressing changes without additional treatment. The patient was ambulating without assistance and with complete closure of all wounds in 10 weeks...
November 2009: Wounds: a Compendium of Clinical Research and Practice
Kostantinos Spiliopoulos, Charalampos Markakis, Periklis Tomos, Hariklia Gakiopoulou, Ioannis Nikolopoulos, Eleftherios Spartalis, Kostantinos Kontzoglou, Michael Safioleas
PURPOSES: The objective of this study was to test the efficacy of an equine pericardial patch for repairing full-thickness defects of the stomach wall. METHODS: Circular defects, 1.5 cm in diameter, were created on the anterior wall of the stomach of 12 female New Zealand rabbits. The defects were repaired by an equine pericardial patch. After euthanasia at different time intervals (3 days to 8 weeks) a macroscopic evaluation of the abdominal cavity (including adhesion scoring), mechanical testing and a histological examination of the stomach were performed...
January 2015: Surgery Today
Genta Chikazawa, Arudo Hiraoka, Yuuki Hirai, Kentaro Tamura, Toshinori Totsugawa, Atsuhisa Ishida, Taichi Sakaguchi, Hidenori Yoshitaka
We performed a late open reintervention for aneurysmal sac enlargement due to persistent type 2 endoleak (PT2EL) after EVAR for 8 of 286 patients. Surgical techniques are as follows: (1) The entire aneurysmal body was exposed. (2) All the aortic branched vessels were ligated. (3) The aneurysmal sac was opened followed by the performance of complete hemostasis. (4) An equine pericardium was wrapped and sutured to the aneurysmal sac to for reinforcement. This method is considered to be one of the feasible options for the treatment of aneurysmal sac re-enlargement after EVAR...
2014: Annals of Vascular Diseases
Akiko Tanaka, Tomonori Shirasaka, Kenji Okada, Yutaka Okita
We describe our experience with a patient who had metastasized pulmonary artery sarcoma, but survived 7 years after diagnosis. A 61-year-old man was diagnosed with pulmonary artery intimal sarcoma after resection of metastatic tumours to the bilateral lungs. The primary lesion in the pulmonary artery trunk extending into the bilateral branches was treated by tumour endoarterectomy followed by chemotherapy. He underwent resections of lung metastases two more times before detection of recurrent obstructive pulmonary artery sarcoma 4 years after the tumour endoarterectomy...
February 2015: European Journal of Cardio-thoracic Surgery
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