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https://www.readbyqxmd.com/read/28222504/bimanual-gesture-imitation-in-alzheimer-s-disease
#1
G Nter Sanin, Thomas Benke
BACKGROUND/OBJECTIVE: Unimanual gesture production or imitation has often been studied in Alzheimer's disease (AD) during apraxia testing. In the present study, it was hypothesized that bimanual motor tasks may be a sensitive method to detect impairments of motor cognition in AD due to increased demands on the cognitive system. METHODS: We investigated bimanual, meaningless gesture imitation in 45 AD outpatients, 38 subjects with mild cognitive impairment (MCI), and 50 normal controls (NC) attending a memory clinic...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28221979/influence-of-transportation-conditions-and-postharvest-disinfection-treatments-on-microbiological-quality-of-fresh-market-tomatoes-cv-nemo-netta-in-a-south-african-supply-chain
#2
M S Sibomana, L W Ziena, S Schmidt, T S Workneh
Postharvest microbial spoilage due to suboptimal transportation and packaging conditions is a key concern for the South African tomato industry. This study investigated the influence of washing with tap water or aqueous disinfectant solutions (chlorinated and anolyte water) on the microbiological quality of tomatoes during storage after transportation in nonrefrigerated trucks along two supply routes when packaged in crates and boxes. Route 1 was 1,093 km from field to storage site, while route 2 was 1,057 km...
February 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28220278/rhodamine-diaminomaleonitrile-conjugate-as-a-novel-colorimetric-fluorescent-sensor-for-recognition-of-cd-2-ion
#3
Perumal Sakthivel, Karuppannan Sekar, Gandhi Sivaraman, Subramanian Singaravadivel
Rhodamine diaminomaleonitrile linked probe (RD-1) shows highly sensitive colorimetric and selective turn-on fluorescent response to Cd(2+) over other metal ions. The fluorescence intensity and absorbance of the probe RD-1 showed a good linearity, with very low detection limits of 18.5 nm. The probe RD-1 was preliminarily applied to the determination of Cd(2+) ion in water samples from river and tap water with satisfying results. The live cell image confocal microscopy, HeLa cell demonstrated that RD-1 had low cytotoxicity with good membrane permeable property is successfully applied to fluorescence microscopic imaging for the detection of Cd(2+) ions...
February 21, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28217868/an-anti-nicotinic-cognitive-challenge-model-using-mecamylamine-in-comparison-with-the-anti-muscarinic-cognitive-challenge-using-scopolamine
#4
A C Baakman, R Alvarez-Jimenez, R Rissmann, E S Klaassen, J Stevens, S C Goulooze, J Burger, E L Swart, J M A van Gerven, G J Groeneveld
INTRODUCTION: The muscarinic acetylcholine receptor antagonist scopolamine is often used for proof-of-pharmacology studies with pro-cognitive compounds. From a pharmacological point of view, it would seem more rational to use a nicotinic rather than a muscarinic anticholinergic challenge to prove pharmacology of a nicotinic acetylcholine receptor agonist. This study aims to characterize a nicotinic anticholinergic challenge model using mecamylamine and to compare it to the scopolamine model...
February 20, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28217069/can-ultrasound-guided-subcostal-transverse-abdominis-plane-block-be-used-as-sole-anesthetic-technique
#5
Pooja Bihani, Pradeep Bhatia, Swati Chhabra, Pradeepika Gangwar
Subcostal transverse abdominis plane (TAP) block anesthetizes area of the abdomen with cutaneous innervation of T6-T10 dermatomes. These abdominal field blocks become very advantageous when cardiac patient presents for noncardiac surgeries as sole anesthetic or as a part of multimodal anesthesia. A 58-year-male came for open surgical repair of subxiphoid incisional hernia developed post coronary artery bypass grafting (CABG). Echocardiography showed hypokinesia of left ventricle (LV) in the left anterior descending (LAD) artery territory, dilated LV, and ejection fraction of 30%, and coronary angiography after 6 months of CABG showed 70% stenosis of LAD...
January 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28217055/ultrasound-guided-transversus-abdominis-plane-block-what-are-the-benefits-of-adding-dexmedetomidine-to-ropivacaine
#6
Manjaree Mishra, Shashi Prakash Mishra, Somendra Pal Singh
BACKGROUND: Ultrasound-guided transversus abdominis plane (TAP) block has recently come up as a modality to take care of postoperative pain. It can somewhat avoid the use of intravenous opioid analgesics and hence to avoid its complications. We have performed a prospective, double-blinded, randomized study to assess the analgesic effect of adding dexmedetomidine to local ropivacaine on TAP block for patients undergoing lower abdominal surgeries. AIM: The aim is to assess whether addition of dexmedetomidine to ropivacaine may bring some improvements to the analgesic efficacy of TAP blocks in patients undergoing lower abdominal surgeries...
January 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28216087/neural-consequences-of-post-exertion-malaise-in-myalgic-encephalomyelitis-chronic-fatigue-syndrome
#7
Dane B Cook, Alan R Light, Kathleen C Light, Gordon Broderick, Morgan R Shields, Ryan J Dougherty, Jacob D Meyer, Stephanie VanRiper, Aaron J Stegner, Laura D Ellingson, Suzanne D Vernon
Post exertion malaise is one of the most debilitating aspects of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, yet the neurobiological consequences are largely unexplored. The objective of the study was to determine the neural consequences of acute exercise using functional brain imaging. Fifteen female Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients and 15 healthy female controls completed 30 minutes of submaximal exercise (70% of peak heart rate) on a cycle ergometer. Symptom assessments (e...
February 16, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28215095/ph-dependence-of-photoinduced-electron-transfer-with-ru-tap-3-2
#8
Ludovic Troian-Gautier, Epiphanie Mugeniwabagara, Luca Fusaro, Cécile Moucheron, Andrée Kirsch-De Mesmaeker, Michel Luhmer
The quenching of the excited state of [Ru(TAP)3](2+) (TAP = 1,4,5,8-tetraazaphenanthrene) by guanosine-5'-monophosphate (GMP), N-acetyltyrosine (N-Ac-Tyr), and hydroquinone (H2Q) has been studied in aqueous solution over a wide range of pH values including, for the first time, strongly acidic media. This quenching by electron transfer was examined by steady-state (1)H photochemically induced dynamic nuclear polarization (photo-CIDNP) as well as by more conventional techniques, among which are pulsed laser-induced transient absorption and emission experiments...
February 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28213767/mountaintop-removal-coal-mining-and-emergent-cases-of-psychological-disorder-in-kentucky
#9
Will H Canu, John Paul Jameson, Ellen H Steele, Michael Denslow
Although mountaintop removal (MTR) coal extraction techniques have been employed in Appalachia for decades, relatively little research has examined its potential psychological impact on people living in close proximity to MTR activity. The current study taps the State Emergency Department Database (Healthcare Cost and Utilization Project, Kentucky State Emergency Department Database, 2008) to examine the relative risk for diagnoses of depressive, substance use, and anxiety disorders originating in areas with and without MTR activity...
February 17, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28213252/multi-pumping-flow-system-for-the-determination-of-boron-in-eye-drops-drinking-water-and-ocean-water
#10
Pablo González, Alexandra Sixto, Moisés Knochen
A novel automated method for the determination of boron based on the use of pulsed flows was developed and applied to the determination of this element in samples of tap water, ocean water and eye drops. The method was implemented by means of a multi-pumping system consisting of three solenoid micropumps and a photometric detector and exploits the reaction of azomethine-H in the presence of boron. The system runs under control of an open-source microcontroller. The main operational parameters were optimized...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213223/electrochemical-determination-of-arsenic-in-natural-waters-using-carbon-fiber-ultra-microelectrodes-modified-with-gold-nanoparticles
#11
Patricio Carrera, Patricio J Espinoza-Montero, Lenys Fernández, Hugo Romero, José Alvarado
We have developed an anodic stripping voltammetry method that employs carbon fiber ultra-microelectrodes modified with gold nanoparticles to determine arsenic in natural waters. Gold nanoparticles were potentiostatically deposited on carbon fiber ultra-microelectrodes at -0.90V (vs SCE) for a time of 15s, to form the carbon fiber ultra-microelectrodes modified with gold nanoparticles. Cyclic voltammetry, electrochemical impedance spectroscopy and scanning electron microscopy coupled to an X-ray microanalysis system were used to check and confirm the presence of gold nanoparticles on the carbon fiber ultra-microelectrodes...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213221/a-novel-fluorescent-aptasensor-for-ultrasensitive-detection-of-microcystin-lr-based-on-single-walled-carbon-nanotubes-and-dapoxyl
#12
Seyed Mohammad Taghdisi, Noor Mohammad Danesh, Mohammad Ramezani, Narjes Ghows, Seyed Ali Mousavi Shaegh, Khalil Abnous
To assure water safety and protect human health, precise and simple analytical approaches are highly desired to determine low concentrations of microcystin-leucine-arginine (MC-LR), a toxin, in both water and serum samples. Herein, a simple, rapid and accurate aptamer-based fluorescent sensor was used for selective recognition of MC-LR, based on single-walled carbon nanotubes (SWNTs) as immobilizers, dapoxyl as a fluorescent dye, DAP-10 as a specific aptamer for dapoxyl and unmodified MC-LR aptamer (Apt) as a sensing ligand...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213127/quantitation-of-lead-210-210-pb-using-lead-203-203-pb-as-a-massless-yield-tracer
#13
D May, A N Nelson, M K Schultz
Determination of Pb-210 ((210)Pb) in aqueous solution is a common radioanalytical challenge in environmental science. Widely used methods for undertaking these analyses (e.g., ASTM D7535) rely on the use of stable lead (Pb) as a yield tracer that takes into account losses of (210)Pb that inevitably occur during elemental/radiochemical separations of the procedures. Although effective, these methods introduce technical challenges that can be difficult to track and potentially introduce uncertainty that can be difficult to quantify...
February 14, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28213055/electrophysiological-measurements-that-can-explain-and-guide-temporary-accelerated-pacing-to-avert-re-occurrence-of-torsade-de-pointes-arrhythmias-in-the-canine-chronic-atrioventricular-block-model
#14
Sofieke C Wijers, Alexandre Bossu, Albert Dunnink, Jet D M Beekman, Rosanne Varkevisser, Alfonso Aranda Hernández, Mathias Meine, Marc A Vos
BACKGROUND: Pacing at higher rates is known to suppress Torsade de Pointes (TdP) arrhythmias. Nevertheless, exact application and mechanism need further clarification. In the anesthetized, canine, chronic atrioventricular block model, ventricular remodeling is responsible for a high and reproducible incidence of TdP upon a challenge with dofetilide. OBJECTIVE: We used this model to investigate by what mechanism accelerated pacing averts TdP and what repolarization parameter could be used to guide temporary applied accelerated pacing (TAP)...
February 14, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28213024/sanitizer-efficacy-in-preventing-cross-contamination-of-heads-of-lettuce-during-retail-crisping
#15
Yangjin Jung, Hyein Jang, Mengqi Guo, Jingwen Gao, Karl R Matthews
This study was conducted to provide information regarding mitigation of cross-contamination through the use of sanitizer during crisping at retail outlets. Seven non-inoculated heads and one inoculated head (≈5 log CFU/g) of lettuce were placed into commercial sink filled with 76 L of tap water (TW), electrolyzed water (EW, free chlorine: 43 ± 6 ppm), lactic acid and phosphoric acid-based sanitizer (LPA, pH 2.89), or citric acid-based sanitizer (CA, pH 2.78) and soaked for 5 min. Two subsequent batches (eight non-inoculated heads per batch) were soaked in the same solution...
June 2017: Food Microbiology
https://www.readbyqxmd.com/read/28210561/thermal-injury-in-tapia-breast-reconstruction-thermal-injury-to-thoracodorsal-artery-perforator-flap
#16
Mikkel Børsen-Koch, Gudjon L Gunnarsson, Jens Ahm Sørensen, Jørn Bo Thomsen
This paper presents two case reports on thermal injury to a breast reconstructed by the TAPIA method. In both cases the injuries were caused by excessive sun exposure. Thermal injury to flaps used in breast reconstruction has previously been described but most commonly in abdominal flaps, which may be due to the relative high frequency of this type of reconstructions. Reports of thermal injury to reconstructions using the Latissimus Dorsi flap are rare. The injuries previously described are most often caused by severe heat exposure...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28209741/frequency-characteristics-of-human-muscle-and-cortical-responses-evoked-by-noisy-achilles-tendon-vibration
#17
Robyn Lynne Mildren, Ryan M Peters, Aimee J Hill, Jean-Sebastien Blouin, Mark Gregory Carpenter, J Timothy Inglis
Noisy stimuli, along with linear systems analysis, have proven to be effective for mapping functional neural connections. We explored the use of noisy (10-115 Hz) Achilles tendon vibration to examine proprioceptive reflexes in the triceps surae muscles in standing healthy young adults (n = 8). We also examined the association between noisy vibration and electrical activity recorded over the sensorimotor cortex using electroencephalography. We applied two-minutes of vibration and recorded ongoing muscle activity of the soleus and gastrocnemii using surface electromyography (EMG)...
February 16, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28209102/diverticulitis-in-the-young-population%C3%A2-reconsidering-conventional-recommendations
#18
U Syed, R Companioni, R Bansal, H Alkhawam, A Walfish
BACKGROUND: In the past diverticulitis was believed to be uncommon in the young population. However, there is growing concern suggesting that these patients develop more severe clinical symptoms and may require more frequent intervention. METHOD: We performed a retrospective chart review of patients with diverticulitis in individuals with age less than 40 years over an 8 year period (2007-2015). Diagnosis was confirmed with a CT scan. In addition to age we took into consideration race, gender, anemia (hematocrit< 41), leukocytosis (WBC > 12), BMI and whether it was an initial episode or recurrence...
July 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/28205433/a-battery-operated-atomic-emission-analyzer-for-waterborne-arsenic-based-on-atmospheric-pressure-glow-discharge-excitation-source
#19
Chun Yang, Dong He, Zhenli Zhu, Huan Peng, Zhifu Liu, Guojun Wen, Jianghao Bai, Hongtao Zheng, Shenghong Hu, Yanxin Wang
In this paper, a sensitive atomic emission spectrometer (AES) based on a new low power and low argon consumption (< 8 W, 100 mL min(-1)) miniature direct current (DC) atmospheric pressure glow discharge (APGD) plasma (3 mm×5 mm) excitation source was developed for the determination of arsenic in water samples. In this method, arsenic in water was reduced to AsH3 by hydride generation (HG), which was then transported to the APGD source for excitation and detected by a compact CCD (charge-coupled device) microspectrometer...
February 16, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28203246/generalization-of-context-specific-training-in-individuals-with-mild-cognitive-impairment-an-event-related-potential-study
#20
Sam C C Chan, Tommy L H Lam, Kenneth N K Fong, Marco Y C Pang, Chetwyn C H Chan
BACKGROUND: This study examined the neural processes associated with the generalization of the effect of context-specific (CS) training to noncontextual situations among individuals with mild cognitive impairment (MCI). METHODS: Fourteen and 16 participants with MCI were randomly allocated to a Chinese calligraphy writing (CW) training or a control group, respectively. The CW participants learned how to write Chinese strokes in a semicursive style to construct characters, tapping on working memory functions...
September 2016: Dementia and Geriatric Cognitive Disorders Extra
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