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https://www.readbyqxmd.com/read/28323519/improvement-of-low-sexual-desire-due-to-antiandrogenic-combined-oral-contraceptives-after-switching-to-an-oral-contraceptive-containing-17%C3%AE-estradiol
#1
Salvatore Caruso, Stefano Cianci, Maria Cariola, Valentina Fava, Salvatore Di Pasqua, Antonio Cianci
OBJECTIVES: To investigate the effects of a combined oral contraceptive (COC) containing 17β-estradiol (E2) 1.5 mg and nomegestrol acetate 2.5 mg (NOMAC/E2) on the sexual health of women affected by low sexual desire due to COCs containing ethinylestradiol. MATERIALS AND METHODS: Eighty-three women (age range 19-32) participated in the study. Sex hormone-binding globulin (SHBG), total testosterone (TT), and free androgen index (FAI) were measured. The Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (FSDS) questionnaires were used to assess sexual function and distress, respectively...
March 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28319850/methylation-of-hpa-axis-related-genes-in-men-with-hypersexual-disorder
#2
Jussi Jokinen, Adrian E Boström, Andreas Chatzittofis, Diana M Ciuculete, Katarina Görts Öberg, John N Flanagan, Stefan Arver, Helgi B Schiöth
Hypersexual Disorder (HD) defined as non-paraphilic sexual desire disorder with components of compulsivity, impulsivity and behavioral addiction, and proposed as a diagnosis in the DSM 5, shares some overlapping features with substance use disorder including common neurotransmitter systems and dysregulated hypothalamic-pituitary-adrenal (HPA) axis function. In this study, comprising 67 HD male patients and 39 male healthy volunteers, we aimed to identify HPA-axis coupled CpG-sites, in which modifications of the epigenetic profile are associated with hypersexuality...
March 10, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28318418/sexuality-and-everydayness-in-a-transnational-context-toward-a-re-imagined-west-china-relationship
#3
Yingying Huang
This paper examines how Chinese immigrants to Canada perceive and experience sexuality in a transnational context as revealed in a qualitative study. It identifies cultural interactions and tensions between 'the West' and 'China' embedded in participants' sexual narratives. Three thematic aspects of sexuality are explored: different views toward 'relationships' and how sex is involved in different stages of a relationship; physical desire and sexual attraction based on individuals' dialogues with contemporaries and their own cross-racial dating experience; and perceptions of sexual risks associated with an increasing awareness of China's opening up, in particular risks associated with attitudes towards condom use...
March 20, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28315587/the-effect-of-l-thyroxine-treatment-on-sexual-function-and-depressive-symptoms-in-men-with-autoimmune-hypothyroidism
#4
Robert Krysiak, Witold Szkróbka, Bogusław Okopień
BACKGROUND: Thyroid autoimmunity and mild hypothyroidism in women seem to be associated with sexual dysfunction and depressive symptoms. Data concerning similar associations in men are limited. The aim of this study was to investigate sexual functioning and depressive symptoms in men with autoimmune hypothyroidism. METHODS: The study population consisted of three groups: men with autoimmune overt hypothyroidism (group A), men with autoimmune subclinical hypothyroidism (group B) and healthy euthyroid males without thyroid autoimmunity (group C)...
January 17, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28291734/safety-assessment-of-the-aqueous-extract-of-the-flowers-of-nymphaea-lotus-linn-nymphaeaceae-acute-neuro-and-subchronic-oral-toxicity-studies-in-albinos-wistar-rats
#5
Mireille Kameni Poumeni, Danielle Claude Bilanda, Paul Désiré Dzeufiet Djomeni, Yolande Sandrine Mengue Ngadena, Marguerite Francine Mballa, Madeleine Chantal Ngoungoure, Agnès Carolle Ouafo, Théophile Dimo, Pierre Kamtchouing
BACKGROUND: Nymphaea lotus Linn (N. lotus) is a medicinal plant widely used in Cameroon popular medicine, to treat neuropsychiatric conditions, male sexual disorders or as food supplement. However, scientific data on the pharmacotoxic profile of this plant are not available. The safety of N. lotus was assessed in acute, neuro- and subchronic toxicity studies by following the OECD guidelines. Effectively, no data have been published until now in regard to its safety on the nervous system...
March 14, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28291031/a-sex-specific-dose-response-curve-for-testosterone-could-excessive-testosterone-limit-sexual-interaction-in-women
#6
Jill M Krapf, James A Simon
Testosterone treatment increases sexual desire and well-being in women with hypoactive sexual desire disorder; however, many studies have shown only modest benefits limited to moderate doses. Unlike men, available data indicate women show a bell-shaped dose-response curve for testosterone, wherein a threshold dosage of testosterone leads to desirable sexual function effects, but exceeding this threshold results in a lack of further positive sexual effects or may have a negative impact. Emotional and physical side-effects of excess testosterone, including aggression and virilization, may counteract the modest benefits on sexual interaction, providing a possible explanation for a threshold dose of testosterone in women...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28287913/skills-vs-pills-comparative-effectiveness-for-low-sexual-desire
#7
Meenakshi Palaniappan, Rachel Heatherly, Laurie Mintz, Kathleen Connelly, Tessa Wimberley, Alexandra Balzer, Danielle Pierini, Katherine Vogel Anderson
This study compared the effectiveness of a skill-based bibliotherapy intervention and a placebo pill intervention purported to be efficacious in increasing women's sexual desire. Forty-five participants were randomized into the two groups after completing pre-test measures of sexual desire and functioning. After completing their interventions, participants completed 6-week post-test, and 12-week follow-up measures. Results demonstrated that when compared to the placebo pill group, the bibliotherapy group made statistically greater gains from pre-test to follow-up in sexual desire and satisfaction...
March 13, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28285412/symptoms-and-impacts-in-non-metastatic-castration-resistant-prostate-cancer-qualitative-study-findings
#8
Erin L Tomaszewski, Pierre Moise, Robert N Krupnick, Jared Downing, Margaret Meyer, Shevani Naidoo, Stefan Holmstrom
OBJECTIVES: We developed a conceptual model to define key concepts associated with patients' experiences with the signs, symptoms, and impacts of non-metastatic castration-resistant prostate cancer (M0-CRPC). METHODS: A targeted review of peer-reviewed literature, and other publicly available information, identified and categorized symptoms and impacts related to early-stage prostate cancer. Semi-structured interviews with five clinical experts helped determine the most relevant and important concepts for patients with M0-CRPC...
March 11, 2017: Patient
https://www.readbyqxmd.com/read/28284776/neural-underpinnings-of-prosexual-effects-induced-by-gamma-hydroxybutyrate-in-healthy-male-humans
#9
Oliver G Bosch, Michael M Havranek, Andrea Baumberger, Katrin H Preller, Robin von Rotz, Marcus Herdener, Rainer Kraehenmann, Philipp Staempfli, Milan Scheidegger, Tim Klucken, Erich Seifritz, Boris B Quednow
Gamma-hydroxybutyrate (GHB) is a GHB-/GABAB-receptor agonist currently used as treatment for narcolepsy but also as a drug of abuse. Non-medical GHB users have repeatedly reported prosexual effects including libido-enhancement and lowering of attractiveness standards for partner selection. Here, we examined the putative prosexual effects of oral GHB in healthy males in two experiments both employing randomized, placebo-controlled, double-blind, balanced, and cross-over study designs. In experiment I, subjective effects of 20 and 35mg/kg GHB vs...
March 8, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28279890/the-impact-of-genital-self-image-on-sexual-function-in-women-with-pelvic-floor-disorders
#10
Jonathan E Handelzalts, Tal Yaakobi, Sigal Levy, Yoav Peled, Arnon Wiznitzer, Haim Krissi
OBJECTIVE: There is conflicting evidence regarding the impact of urinary incontinence and pelvic organ prolapse on overall sexual function. However, psychological variables thought to be associated with sexual function, have not been fully explored. We assessed the sexual functioning of women with pelvic floor disorders while measuring for psychological factors such as distress and genital self-image. STUDY DESIGN: In a cross-sectional study, 155 women in an urogynecology outpatient clinic of a tertiary health center completed a demographic questionnaire, the Brief Symptom Index-18 (BSI-18), Pelvic Floor Distress Inventory-20 (PFDI-20), Genital Self-Image Scale-20 (GSIS-20) and the Female Sexual Function Index (FSFI)...
February 28, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28278441/facilitation-of-sexual-behavior-in-ovariectomized-rats-by-estradiol-and-testosterone-a-preclinical-model-of-androgen-effects-on-female-sexual-desire
#11
Sherri Lee Jones, Nafissa Ismail, James G Pfaus
In the United States and Canada, there are no approved treatments for hypoactive sexual desire disorder in postmenopausal women. Testosterone improves female sexual desire in naturally- and surgically-menopausal women maintained on estrogen replacement therapy, and long-term safety data from randomized placebo-controlled clinical trials has yielded promising results. However, the mechanisms associated with its efficacy are not known, and could be addressed using preclinical rodent models; yet there is no systematic evaluation of the effects of estradiol and testosterone on female rat sexual behavior...
February 17, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28277469/correlation-between-transperineal-3-dimensional-ultrasound-measurements-of-levator-hiatus-and-female-sexual-function
#12
Serdar Aydin, Rabia Zehra Bakar, Çağri Arioğlu Aydin, Seda Ateş
OBJECTIVE: The aim of this study is to investigate the association of sexual functions with levator hiatus biometry measurements and levator ani muscle defect. METHODS: In 62 heterosexual, sexually active premenopausal women without pelvic floor disorders or urinary incontinence, 3-dimensional transperineal ultrasound imaging was used. Two 3-dimensional volumes were recorded, one at rest and one on Valsalva maneuver. Levator biometry measurements and levator defect were evaluated in an axial plane...
March 9, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28276924/latino-men-who-have-sex-with-transgendered-women-the-influence-of-heteronormativity-homonegativity-and-transphobia-on-gender-and-sexual-scripts
#13
Miguel Muñoz-Laboy, Nicolette Severson, Ethan Levine, Omar Martínez
Latino men who have sex with transgender women make up an overlooked sector of the population that requires more attention than is currently given in sexuality and gender studies, particularly in regard to their non-commercial, long-term sexual and romantic relationships with transgender women. Sixty-one sexual histories were selected for this qualitative analysis from a larger study on Latino male bisexuality in the New York City metropolitan area. Findings suggest that participants' sexual and gender scripts with transgender women are strongly regulated by heteronormativity...
February 13, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28271984/need-for-desire-drugs-debated
#14
Jan Greene
Some see a big market for medications for low libido in women. But sales of Addyi have been slow. Has a normal experience been unnecessarily medicalized? One of many factors in the debate is whether women#x02019;s sexual response tends to be more spontaneous or responsive.
February 2017: Managed Care
https://www.readbyqxmd.com/read/28267442/effects-of-female-genital-mutilation-cutting-on-the-sexual-function-of-sudanese-women-a-cross-sectional-study
#15
Abdulrahim A Rouzi, Rigmor C Berg, Nora Sahly, Susan Alkafy, Faten Alzaban, Hassan Abduljabbar
BACKGROUND: Female Genital Mutilation/Cutting (FGM/C) is a cultural practice that involves several types of removal or other injury to the external female genitalia for non-medical reasons. While much international research has focused on the health consequences of the practice, little is known about sexual functioning among women with various types of FGM/C. OBJECTIVE(S): To assess the impact of FGM/C on the sexual functioning of Sudanese women. STUDY DESIGN: This is a cross-sectional study conducted at Doctor Erfan and Bagedo Hospital, Jeddah, Saudi Arabia...
March 3, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28265321/prepuce-health-and-childhood-circumcision-choices-in-canada
#16
REVIEW
Emmanuel O Abara
INTRODUCTION: Worldwide, almost 100% of boys are born with penises with a "hood" called prepuce or foreskin. In the course of the boy's life, the prepuce can be circumcised, can become affected by diseased (e.g., phimosis), or a can become infected and hurt the neonate (and his sexual partner) in adulthood. The objectives of this report are to: 1) review the state, function, fate, and care of the prepuce in childhood, with focus on the neonate, in Canada; 2) understand the current practice of childhood male circumcision in terms of age, indications, performers, techniques, outcomes, and education; and 3) consider ways to sustain a good healthcare professional-parental dialogue for safe practices that are accessible, acceptable, and culturally sensitive in the care of the prepuce...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28263396/pregnancy-experiences-of-female-sex-workers-in-adama-city-ethiopia-complexity-of-partner-relationships-and-pregnancy-intentions
#17
Eileen A Yam, Aklilu Kidanu, Brady Burnett-Zieman, Nanlesta Pilgrim, Jerry Okal, Assefa Bekele, Daniel Gudeta, Georgina Caswell
Research and programs for female sex workers (FSWs) tend to focus exclusively on HIV prevention, with little attention paid to how pregnancy affects their lives. We examine the circumstances surrounding pregnancy and childbirth among women selling sex in Ethiopia. In Adama City, researchers asked 30 FSWs aged 18 and older who had ever been pregnant to participate in in-depth interviews. The women reported on pregnancies experienced both before and after they had begun selling sex. They identified some of the fathers as clients, former partners, and current partners, but they did not know the identities of the other fathers...
March 6, 2017: Studies in Family Planning
https://www.readbyqxmd.com/read/28261120/the-desire-of-parenthood-intuitive-co-parental-behaviors-and-quality-of-couple-relationship-among-italian-and-belgian-same-sex-and-opposite-sex-couples
#18
Marina Miscioscia, Adelaide Blavier, Paolo R Pagone, Alessandra Simonelli
Studies that focused on family issues have allowed a great understanding of the aspects related to its subsystems, such as parenting desire and its expectations, couples' satisfaction and quality of child's outcomes. All these aspects are greatly interconnected and contribute to the creation of specific family dynamics, such as the quality of family interactions. The present study focuses on intuitive co-parental behaviors and the quality of couple relationship observed during the decision process (intention and desire) to be (or become) parents...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28260139/the-impact-of-mastectomy-type-on-the-female-sexual-function-index-fsfi-satisfaction-with-appearance-and-the-reconstructed-breast-s-role-in-intimacy
#19
K Rojas, M Onstad, C Raker, M A Clark, A Stuckey, J Gass
BACKGROUND: As mastectomy rates increase and overall survival for early breast cancer improves, a better understanding of the long-term consequences of mastectomy is needed. We sought to explore the correlation of specific mastectomy type with the Female Sexual Function Index (FSFI), body image satisfaction, and the reconstructed breast's role in intimacy. METHODS: This study is a secondary analysis of a cross-sectional survey including a retrospective chart review...
March 4, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28253004/consistency-and-inconsistency-among-romantic-partners-over-time
#20
Paul W Eastwick, K Paige Harden, Jennifer A Shukusky, Taylor Anne Morgan, Samantha Joel
Theoretical perspectives on mating differentially emphasize whether (and why) romantic partner selection and maintenance processes derive from stable features of individuals (e.g., mate value, mate preferences, relationship aptitude) and their environments (e.g., social homogamy) rather than adventitious, dyad-specific, or unpredictable factors. The current article advances our understanding of this issue by assessing how people's actual romantic partners vary on constructs commonly assessed in evolutionary psychology (Study 1), sociology (Study 2), and close relationships (Study 3)...
March 2, 2017: Journal of Personality and Social Psychology
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