Lyubka Tancheva, Reni Kalfin, Borislav Minchev, Diamara Uzunova, Krasimira Tasheva, Elina Tsvetanova, Almira Georgieva, Albena Alexandrova, Miroslava Stefanova, Ayten Solak, Maria Lazarova, Yordan Hodzhev, Valya Grigorova, Dobri Yarkov, Polina Petkova-Kirova
Alzheimer's disease manifests as a complex pathological condition, with neuroinflammation, oxidative stress and cholinergic dysfunction being a few of the many pathological changes. Due to the complexity of the disease, current therapeutic strategies aim at a multitargeted approach, often relying on a combination of substances with versatile and complementary effects. In the present study, a unique combination of α-lipoic acid, citicoline, extracts of leaves from olive tree and green tea, vitamin D3, selenium and an immune-supporting complex was tested in scopolamine-induced dementia in rats...
November 28, 2023: Antioxidants (Basel, Switzerland)