Patricia Santos Reis, Durval Campos Kraychete, Emilie de Magalhães Pedreira, Eduardo Silva Reis Barreto, César Romero Antunes Júnior, Vinicius Borges Alencar, Anna Karla do Nascimento Souza, Liliane Elze Falcão Lins-Kusterer, Liana Maria Torres de Araujo Azi
OBJECTIVE: This systematic literature review aims to evaluate the effectiveness of transdermal opioids in managing cancer pain and their impact on the quality of life (QoL) of patients. DATA SOURCES: A systematic literature review conducted following the PRISMA protocol, focusing on randomized clinical trials found in the Lilacs, Embase, PubMed, and SciELO databases over the last 20 years. STUDY SELECTION AND DATA EXTRACTION: We included randomized clinical trials, published in English, Portuguese, or Spanish, which assessed the impact of transdermal opioids on the QoL...
April 24, 2024: Annals of Pharmacotherapy