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Calcium Hydroxide

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https://www.readbyqxmd.com/read/29153731/bioactivity-of-photoactivated-functionalized-nanoparticles-assessed-in-lipopolysaccharide-contaminated-root-canals-in%C3%A2-vivo
#1
Annie Shrestha, Shimon Friedman, Calvin D Torneck, Anil Kishen
INTRODUCTION: The persistence of dentin-bound lipopolysaccharides (LPS) in disinfected root canals impedes treatment outcomes of endodontic procedures. This study assessed the effects of photoactivated rose bengal-functionalized chitosan nanoparticles (CSRBnps) on LPS-contaminated root dentin in vivo using an intraosseous implantation model and neotissue formation as a marker. METHODS: Fifty human, 3-mm-long root segments with a 1.2-mm canal lumen were divided into 5 groups (n = 10): group 1, canals not contaminated; group 2, canals contaminated with Pseudomonas aeruginosa LPS; group 3, canals contaminated and disinfected with sodium hypochlorite (NaOCl); group 4, canals contaminated and disinfected with NaOCl and calcium hydroxide; and group 5, canals contaminated and disinfected with NaOCl and CSRBnps (300 μg/mL) with photoactivation (λ = 540 nm, 40 J/cm(2))...
November 15, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29142877/removal-efficacy-and-cytotoxicity-of-a-calcium-hydroxide-paste-using-n-2-methyl-pyrrolidone-as-a-vehicle
#2
Myung-Jin Lim, Hyun-Jin Jang, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
Objectives: This study investigated the removal efficacy and cytotoxicity of a newly developed calcium hydroxide paste (cleaniCal, Maruchi) using N-2-methyl-pyrrolidone (NMP) as a vehicle in comparison with ApexCal (Ivoclar Vivadent) and Calcipex II (Nishika), which use different vehicles such as polyethylene glycol and propylene glycol, respectively. Materials and Methods: Thirty maxillary premolars with oval-shaped canals were divided into 3 groups and the teeth were filled with one of the pastes...
November 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29125622/fermentation-cover-brine-reformulation-for-cucumber-processing-with-low-salt-to-reduce-bloater-defect
#3
Y Zhai, I M Pérez-Díaz
Reformulation of calcium chloride (CaCl2 ) cover brine for cucumber fermentation was explored as a mean to minimize the incidence of bloater defect. This study particularly focused on cover brine supplementation with calcium hydroxide (Ca[OH]2 ), sodium chloride (NaCl), and acids to enhance buffer capacity, inhibit the indigenous carbon dioxide (CO2 )- producing microbiota, and decrease the solubility of the gas. The influence of the cover brine formulations tested, on the cucumber fermentation microbiota, biochemistry, CO2 production, and bloating defect was studied using metagenetics, HPLC analysis, a portable gas analyzer and bloater index, respectively...
November 10, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29116496/influence-of-a-calcium-hydroxide-based-intracanal-dressing-on-the-quality-of-the-root-canal-filling-assessed-by-capillary-flow-porometry
#4
Amir-Teymour Moinzadeh, Roeland J G De Moor, Mieke A A De Bruyne
OBJECTIVE: The objective of this study is to evaluate the influence of a calcium hydroxide intracanal dressing (CH) on the short- and long-term sealing ability of the root canal filling using capillary flow porometry (CFP). MATERIALS AND METHODS: To verify the repeatability of the method, five obturated specimens were submitted to CFP. Measurements were repeated three times and compared with the non-parametric Friedman test. Forty-five instrumented palatal roots were randomly divided into three groups...
November 7, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29116494/clinical-and-microbiological-effectiveness-of-photodynamic-therapy-on-primary-endodontic-infections-a-6-month-randomized-clinical-trial
#5
Rachel Garcia de Miranda, Ana Paula Vieira Colombo
INTRODUCTION: This short-term randomized controlled trial evaluated the effectiveness of photodynamic therapy (PDT) on clinical success (periapical healing) and on the microbiota of primary endodontic infections. METHODS: Thirty-two patients presenting mandibular molars with apical periodontitis (one tooth/patient) were selected and randomly allocated into two therapeutic groups: control (chemo-mechanical debridement [CMD]; n = 16) and PDT (CMD + PDT; n = 16)...
November 7, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29104387/evaluation-of-antimicrobial-efficacy-of-various-intracanal-medicaments-in-primary-teeth-an-in-vivo-study
#6
Brahmananda Dutta, Kanika S Dhull, Debasmita Das, P V Samir, Rajnish K Verma, Nipa Singh
Introduction: Bacteria and their products play a primary etiological role in the initiation and perpetuation of pulpoperiapical pathosis. Intracanal medication is important for endodontic success as it eliminates microorganisms that persist after chemomechanical preparation. Aim: To compare antimicrobial efficacy of calcium hydroxide powder, triple antibiotic paste, calcium hydroxide with 2% chlorhexidine solution, and triple antibiotic paste with 2% chlorhexidine solution...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29099365/removal-of-calcium-hydroxide-intracanal-medicament-by-different-irrigants-and-irrigating-techniques-a-cone-beam-computed-tomography-analysis
#7
Prasanna Neelakantan, Priyanka Sriraman, James L Gutmann
The aim of this study was to use cone beam computed tomography (CBCT) to evaluate the removal of calcium hydroxide (Ca[OH]2) from root canals after using different irrigation and activation protocols. Root canals (n = 128) were filled with Ca(OH)2 and scanned using CBCT. The Ca(OH)2 was removed after 1 week using 1 of 12 groups (G1-G12) according to the final irrigating solution: G1, 6% sodium hypochlorite (NaOCl) + 18% etidronic acid (EA) with no activation; G2, NaOCL + EA + passive ultrasonic irrigation (PUI); G3, NaOCl + EA + Finishing File (FF); G4, NaOCl + EA + NaviTip FX irrigation needle (NTFX); G5, 3% NaOCl + 17% ethylenediaminetetraacetic acid (EDTA) with no activation; G6, NaOCl + EDTA + PUI; G7, NaOCl + EDTA + FF; G8, NaOCl + EDTA + NTFX; G9, 3% NaOCl with no activation; G10, NaOCl + PUI; G11, NaOCl + FF; G12, NaOCL + NTFX...
November 2017: General Dentistry
https://www.readbyqxmd.com/read/29079452/use-of-sodium-trimetaphosphate-in-the-inhibition-of-dentin-matrix-metalloproteinases-and-as-a-remineralizing-agent
#8
Rafael Simões Gonçalves, Polliana Mendes Candia Scaffa, Marina Ciccone Giacomini, Marília Afonso Rabelo Buzalaf, Heitor Marques Honório, Linda Wang
OBJECTIVES: Because of its ability to act as an antiproteolytic agent, the effect of sodium trimetaphosphate (STMP) against specific enzymes extracted from sound dentin and its performance under acidic challenge on demineralized dentin were investigated. METHODS: The antiproteolytic potential of STMP (0.5%, 1.0%, and 1.5%) was assessed in triplicate by zymography. For the evaluation of remineralization activity, 50 bovine-root dentin specimens were selected and randomly divided into 5 groups (n=10)...
October 24, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29073902/clinical-and-radiographic-evaluation-of-pulpectomy-in-primary-teeth-a-18-months-clinical-randomized-controlled-trial
#9
Xiaoxian Chen, Xinggang Liu, Jie Zhong
BACKGROUND: To avoid untoward changes when primary teeth are replaced by permanent teeth, resorption of the material used in primary teeth root canal filling should occur at the same rate as root resorption. The Aim of this study was to compare the success rates of a mixed primary root canal filling (MPRCF, ingredients: zinc oxide-eugenol [ZOE], iodoform, calcium hydroxide) to those of ZOE and Vitapex in pulpectomised primary molars. METHODS: One hundred and sixty primary molars from 155 children (average age 5...
October 27, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/29070160/bioactive-tricalcium-silicate-based-dentin-substitute-as-an-indirect-pulp-capping-material-for-primary-teeth-a-12-month-follow-up
#10
Arturo Garrocho-Rangel, Karina Quintana-Guevara, Rocío Vázquez-Viera, Juana María Arvizu-Rivera, Héctor Flores-Reyes, Diana María Escobar-García, Amaury Pozos-Guillén
PURPOSE: The purpose of this study was to evaluate the clinical and radiographic outcomes of a bioactive tricalcium silicate [Ca3SiO5]-based dentin substitute and a light-activated calcium hydroxide [Ca(OH)2]-based liner as indirect pulp treatment (IPT) interventions for vital primary molars with carious lesions approaching the pulp. METHODS: Eighty children, aged four to eight years old, with 160 bilateral primary teeth without signs or symptoms of irreversibly inflamed or degenerative pulp tissue were treated in a split-mouth design trial comparing IPT using Ca3SiO5 or Ca(OH)2...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29070158/partial-pulpotomy-in-immature-permanent-molars-after-carious-exposures-using-different-hemorrhage-control-and-capping-materials
#11
Beste Özgür, Serdar Uysal, H Cem Güngör
PURPOSE: This study compared the outcome of partial pulpotomies with mineral trioxide aggregate (MTA) or calcium hydroxide (CH) following hemorrhage control with 2.5 percent sodium hypochlorite (SH) or 0.9 percent sterile saline (SS) solutions in cariously exposed immature permanent molars. METHODS: Following removal of two to three mm of the pulp at the exposure site, 80 Class I cavities were randomly allocated to four groups according to the hemorrhage control agent and pulp-capping material used: (1) group one-SH plus MTA; (2) group two-SS plus MTA; (3) group three-SH plus CH; (4) group four-SS plus CH...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29070150/use-of-vital-pulp-therapies-in-primary-teeth-with-deep-caries-lesions
#12
Vineet Dhar, Abdullah A Marghalani, Yasmi O Crystal, Ashok Kumar, Priyanshi Ritwik, Ozlem Tulunoglu, Laurel Graham
PURPOSE: This manuscript presents evidence-based guidance on the use of vital pulp therapies for treatment of deep caries lesions in children. A guideline panel convened by the American Academy of Pediatric Dentistry formulated evidence-based recommendations on three vital pulp therapies: indirect pulp treatment (IPT; also known as indirect pulp cap), direct pulp cap (DPC), and pulpotomy. METHODS: The basis of the guideline's recommendations was evidence from "Primary Tooth Vital Pulp Therapy: A Systematic Review and Meta-Analysis...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29068418/sealing-ability-of-alkaline-endodontic-cements-versus-resin-cements
#13
Yu-Yao Teoh, Basil Athanassiadis, Laurence J Walsh
Penetration of oral bacteria through root fillings leads to their long term failure. Dimensionally stable alkaline cements have been developed. A saliva challenge model was used to compare resistance to bacterial penetration of these alkaline cements to conventional root fillings that combine gutta percha (GP) with epoxy resin sealers. A sample of 140 human roots with single straight canals prepared to standard length and canal size were obturated with mineral trioxide aggregate (MTA) (Nex MTA or MTAmix), with an alkaline calcium hydroxide hard setting cement (Supercal), or with GP and a resin cement (either AH-Plus or Zirmix)...
October 25, 2017: Materials
https://www.readbyqxmd.com/read/29065542/aspects-of-solvent-chemistry-for-calcium-hydroxide-medicaments
#14
REVIEW
Basil Athanassiadis, Laurence J Walsh
Calcium hydroxide pastes have been used in endodontics since 1947. Most current calcium hydroxide endodontic pastes use water as the vehicle, which limits the dissolution of calcium hydroxide that can be achieved and, thereby, the maximum pH that can be achieved within the root canal system. Using polyethylene glycol as a solvent, rather than water, can achieve an increase in hydroxyl ions release compared to water or saline. By adopting non-aqueous solvents such as the polyethylene glycols (PEG), greater dissolution and faster hydroxyl ion release can be achieved, leading to enhanced antimicrobial actions, and other improvements in performance and biocompatibility...
October 23, 2017: Materials
https://www.readbyqxmd.com/read/29054741/virucidal-efficacy-of-food-additive-grade-calcium-hydroxide-against-surrogate-of-human-norovirus
#15
Natthanan Sangsriratanakul, Chiharu Toyofuku, Mayuko Suzuki, Miyuki Komura, Masashi Yamada, Md Shahin Alam, Sakchai Ruenphet, Dany Shoham, Kouji Sakai, Kazuaki Takehara
An alkaline agent, namely, food additive grade calcium hydroxide (FdCa(OH)2) in the solution, powder and suspension forms was evaluated as a virucidal agent, using a murine norovirus (MNV) as the surrogate for human norovirus. The main constituent of FdCa(OH)2 is Ca(OH)2, which has pH 13 in 0.17% solution. The results showed that 0.17% FdCa(OH)2 solution could inactivate MNV within 30s even in the presence of organic materials (5% fetal bovine serum (FBS)). In a contaminated surface experiment, MNV with 5% FBS was inoculated on rayon sheets, and the result showed FdCa(OH)2 solution could markedly reduce virus titer within 1min...
January 2018: Journal of Virological Methods
https://www.readbyqxmd.com/read/29042719/a-novel-conservative-approach-combining-sealbio-and-surgical-fenestration-for-healing-of-large-periapical-cystic-lesions-of-endodontic-origin-a-pilot-study
#16
Naseem Shah
OBJECTIVES: To evaluate the treatment outcome of large periapical cystic lesions treated by combining two novel, conservative approaches, "SealBio" and "Surgical Fenestration". MATERIALS AND METHODS: Five cases (4M:1F, age range 14-38 years, mean age 24.5 years) of large periapical cystic lesions, diagnosed on clinical and radiographic examination, were included in the study. After informed consent, endodontic treatment was initiated; chemo-mechanical preparation and intra-canal dressing of calcium hydroxide was given...
July 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29032823/bortezomib-facilitates-reparative-dentin-formation-after-pulp-access-cavity-preparation-in-mouse-molar
#17
Jae-Kwang Jung, Gi-Jeong Gwon, Sanjiv Neupane, Wern-Joo Sohn, Ki-Rim Kim, Ji-Youn Kim, Seo-Young An, Tae-Yub Kwon, Chang-Hyeon An, Youngkyun Lee, Jae-Young Kim, Jung-Hong Ha
INTRODUCTION: The aim of this study was to evaluate in vitro and ex vivo roles of bortezomib, a proteasome inhibitor that binds to the active site of the 26S proteasome, in tertiary dentin formation. METHODS: We established pulpal access cavity preparation that was treated with or without bortezomib before direct pulp capping with a calcium hydroxide-based material. We also analyzed bone morphogenetic protein (Bmp)- and Wnt-related signaling molecules using quantitative real-time polymerase chain reaction...
October 9, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29032822/evaluation-of-the-cytotoxicity-and-biocompatibility-of-new-resin-epoxy-based-endodontic-sealer-containing-calcium-hydroxide
#18
Luciano Tavares Angelo Cintra, Francine Benetti, Índia Olinta de Azevedo Queiroz, Luciana Louzada Ferreira, Loiane Massunari, Carlos Roberto Emerenciano Bueno, Sandra Helena Penha de Oliveira, João Eduardo Gomes-Filho
INTRODUCTION: Many endodontic sealers are available, but the search for the ideal sealer continues. This study evaluated the cytotoxicity and biocompatibility of Sealer Plus, a new resin epoxy-based endodontic sealer containing calcium hydroxide. AH Plus, Endofill, and SimpliSeal endodontics sealers were used for comparison. METHODS: L929 fibroblasts were cultured, and an MTT assay was used to determine the cytotoxicity of the sealer extracts at 6, 24, 48, and 72 hours...
October 9, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28976847/effect-of-light-activation-of-pulp-capping-materials-and-resin-composite-on-dentin-deformation-and-the-pulp-temperature-change
#19
C J Soares, M S Ferreira, A A Bicalho, M de Paula Rodrigues, Ssl Braga, A Versluis
OBJECTIVES: To analyze the effect of pulp-capping materials and resin composite light activation on strain and temperature development in the pulp and on the interfacial integrity at the pulpal floor/pulp-capping materials in large molar class II cavities. METHODS: Forty extracted molars received large mesio-occlusal-distal (MOD) cavity bur preparation with 1.0 mm of dentin remaining at the pulp floor. Four pulp-capping materials (self-etching adhesive system, Clearfil SE Bond [CLE], Kuraray), two light-curing calcium hydroxide cements (BioCal [BIO], Biodinâmica, and Ultra-Blend Plus [ULT], Ultradent), and a resin-modified glass ionomer cement- (Vitrebond [VIT], 3M ESPE) were applied on the pulpal floor...
October 4, 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28956355/the-synthetic-human-beta-defensin-3-c15-peptide-exhibits-antimicrobial-activity-against-streptococcus-mutans-both-alone-and-in-combination-with-dental-disinfectants
#20
Ki Bum Ahn, A Reum Kim, Kee-Yeon Kum, Cheol-Heui Yun, Seung Hyun Han
Streptococcus mutans is a major etiologic agent of human dental caries that forms biofilms on hard tissues in the human oral cavity, such as tooth and dentinal surfaces. Human β-defensin-3 (HBD3) is a 45-amino-acid natural antimicrobial peptide that has broad spectrum antimicrobial activity against bacteria and fungi. A synthetic peptide consisting of the C-terminal 15 amino acids of HBD3 (HBD3-C15) was recently shown to be sufficient for its antimicrobial activity. Thus, clinical applications of this peptide have garnered attention...
October 2017: Journal of Microbiology / the Microbiological Society of Korea
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