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Type 1 diabetes pediatric

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https://www.readbyqxmd.com/read/27913607/autoimmune-comorbidities-in-hashimoto-s-thyroiditis-different-patterns-of-association-in-adulthood-and-childhood-adolescence
#1
R M Ruggeri, F Trimarchi, G Giuffrida, R Certo, E Cama, A Campennì, A Alibrandi, F De Luca, M Wasniewska
OBJECTIVE: Hashimoto's thyroiditis (HT), the most common autoimmune thyroid disease at any age, is often associated with other autoimmune diseases. The present study was aimed to describe the type and frequency of non-thyroidal autoimmune diseases (NTADs) in HT patients and to delineate the clinical pattern of diseases clustering in pediatric/adolescent and adult age. DESIGN: Cross-sectional study. METHODS: 1053 newly diagnosed HT patients (500 adults (467 F, mean age 40...
February 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27906802/anti-tissue-transglutaminase-normalization-post-diagnosis-in-children-with-celiac-disease
#2
Daniela Migliarese Isaac, Seema Rajani, Maryna Yaskina, Hien Q Huynh, Justine M Turner
OBJECTIVES: Limited pediatric data exist examining the trend and predictors of anti-tissue transglutaminase (atTG) normalization over time in children with celiac disease (CD). We aimed to evaluate time to normalization of atTG in children after CD diagnosis, and to assess for independent predictors impacting this duration. METHODS: A retrospective chart review was completed in pediatric CD patients diagnosed from 2007 to 2014 at the Stollery Children's Hospital Celiac Clinic (Edmonton, Alberta)...
November 30, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27903117/risk-factors-associated-with-the-surgical-management-of-craniopharyngiomas-in-pediatric-patients-analysis-of-1961-patients-from-a-national-registry-database
#3
Joshua Bakhsheshian, Diana L Jin, Ki-Eun Chang, Ben A Strickland, Dan A Donoho, Steven Cen, William J Mack, Frank Attenello, Eisha A Christian, Gabriel Zada
OBJECTIVE Patient demographic characteristics, hospital volume, and admission status have been shown to impact surgical outcomes of sellar region tumors in adults; however, the data available following the resection of craniopharyngiomas in the pediatric population remain limited. The authors sought to identify potential risk factors associated with outcomes following surgical management of pediatric craniopharyngiomas. METHODS The Nationwide Inpatient Sample database and Kids' Inpatient Database were analyzed to include admissions for pediatric patients (≤ 18 years) who underwent a transcranial or transsphenoidal craniotomy for resection of a craniopharyngioma...
December 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27893657/status-of-serum-magnesium-in-egyptian-children-with-type-1-diabetes-and-its-correlation-to-glycemic-control-and-lipid-profile
#4
Doaa Shahbah, Amr Abo El Naga, Tamer Hassan, Marwa Zakaria, Mohamed Beshir, Salah Al Morshedy, Mohamed Abdalhady, Ezzat Kamel, Doaa Abdel Rahman, Lamiaa Kamel, May Abdelkader
Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency, having 25% to 39% prevalence. This deficit could be associated with the development of late diabetic complications, especially macroangiopathy.We aimed to evaluate the status of serum Mg in children with type 1 diabetes and assess its relation to glycemic control and lipid profile.We included 71 Egyptian children with type 1diabetes having their follow-up at Pediatric Endocrinology outpatient clinic, Zagazig University Hospital and 71 age- and sex-matched control...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27889401/clinical-and-psychosocial-outcomes-of-a-structured-transition-program-among-young-adults-with-type-1-diabetes
#5
Elizabeth A Pyatak, Paola A Sequeira, Cheryl L P Vigen, Marc J Weigensberg, Jamie R Wood, Lucy Montoya, Valerie Ruelas, Anne L Peters
PURPOSE: We identified and treated young adults with type 1 diabetes who had been lost to follow-up during their transfer from pediatric to adult care, comparing their clinical, psychosocial, and health care utilization outcomes to participants receiving continuous care (CC) throughout the transition to adult care. METHODS: Individuals in their last year of pediatric care (CC group, n = 51) and individuals lost to follow-up in the transfer to adult care ("lapsed care" [LC] group, n = 24) were followed prospectively for 12 months...
November 23, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27878914/severe-hypoglycemia-rates-are-not-associated-with-hba1c-a-cross-sectional-analysis-of-3-contemporary-pediatric-diabetes-registry-databases
#6
Aveni Haynes, Julia M Hermann, Kellee M Miller, Sabine E Hofer, Timothy W Jones, Roy W Beck, David M Maahs, Elizabeth A Davis, Reinhard W Holl
OBJECTIVE: To examine the association between glycated hemoglobin (HbA1c) and severe hypoglycemia rates in patients with type 1 diabetes receiving usual care, by analysing data from the US Type 1 Diabetes Exchange (T1DX), German/Austrian Diabetes Patienten Verlaufsdokumenation (DPV), and Western Australian Children Diabetes Database (WACDD) diabetes registries. METHODS: Data for patients with type 1 diabetes, aged <18 years with a minimum duration of diabetes of 2 years, were extracted from each registry for a 12-month observation period between 2011 and 2012 (7,102 T1DX, 18,887 DPV, and 865 WACDD)...
November 23, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27855143/trends-in-obesity-among-participants-aged-2-4-years-in-the-special-supplemental-nutrition-program-for-women-infants-and-children-united-states-2000-2014
#7
Liping Pan, David S Freedman, Andrea J Sharma, Karen Castellanos-Brown, Sohyun Park, Ray B Smith, Heidi M Blanck
Childhood obesity is associated with negative health consequences in childhood (1) that continue into adulthood (2), putting adults at risk for type 2 diabetes, cardiovascular disease, and certain cancers (1). Obesity disproportionately affects children from low-income families (3). Through a collaboration with the United States Department of Agriculture (USDA), CDC has begun to use data from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) Participants and Program Characteristics (WIC PC) to replace the Pediatric Nutrition Surveillance System (PedNSS) (4,5) for obesity surveillance among young children from low-income families...
November 18, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27853013/ocular-manifestations-of-type-1-diabetes-mellitus-in-pediatric-population
#8
Handan Akil, Ayse Derya Buluş, Nesibe Andiran, Mehmet Numan Alp
CONTEXT: To evaluate the necessity of ocular screening in Type 1 diabetes mellitus (DM). AIMS: This study aims to investigate the diabetes-related ocular changes according to the glycosylated hemoglobin (HbA1c) level and duration of diabetes in children and compare the results with nondiabetic healthy children. SETTINGS AND DESIGN: Observational cross-sectional study designed by ophthalmology and pediatric endocrinology clinics. SUBJECTS AND METHODS: Forty-two children with Type 1 DM, 42 healthy gender- and age-matched children as controls were enrolled...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27849238/diabetes-mellitus-in-childhood-an-emerging-condition-in-the-21st-century
#9
Thais Della Manna, Nuvarte Setian, Roberta Diaz Savoldelli, Dulce Rondina Guedes, Hilton Kuperman, Hamilton Cabral Menezes, Leandra Steinmetz, Louise Cominato, Vaê Dichtchekenian, Durval Damiani
The International Diabetes Federation (IDF-2015) estimates the existence of 30,900 children under 15 years old with type 1 diabetes mellitus (DM1) in Brazil, and an increase of 3.0% per year is expected. This review focused on meta-analysis and pediatric diabetes update articles in order to draw attention to the need of planning coping strategies to support this serious public health problem in coming years. DM1 is considered an immuno-mediated disease with a complex transmission influenced by genetic and environmental factors responsible for a gradual destruction of the insulin producing pancreatic beta cells...
September 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27847281/identification-of-pediatric-patients-with-celiac-disease-based-on-serology-and-a-classification-and-regression-tree-analysis
#10
Anna Ermarth, Matthew Bryce, Stephanie Woodward, Gregory Stoddard, Linda Book, M Kyle Jensen
BACKGROUND & AIMS: Celiac disease is detected using serology and endoscopy analyses. We used multiple statistical analyses of a geographically isolated population in the United States to determine whether a single serum screening can identify individuals with celiac disease. METHODS: We performed a retrospective study of 3555 pediatric patients (18 years old or younger) in the intermountain West region of the United States from January 1, 2008 through September 30, 2013...
November 12, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27843339/the-danish-adult-diabetes-registry
#11
REVIEW
Marit Eika Jørgensen, Jette K Kristensen, Gitte Reventlov Husted, Charlotte Cerqueira, Peter Rossing
AIM OF THE DATABASE: The aim of the Danish Adult Diabetes Registry (DADR) is to provide data from both the primary health care sector (general practice [GP]) and the secondary sector (specialized outpatient clinics) to assess the quality of treatment given to patients with diabetes. The indicators represent process and outcome indicators selected from the literature. STUDY POPULATION: The total diabetes population in Denmark is estimated to be ~300,000 adult diabetes patients...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27842589/the-course-of-diabetes-in-children-adolescents-and-young-adults-does-the-autoimmunity-status-matter
#12
Rasa Verkauskiene, Evalda Danyte, Rimante Dobrovolskiene, Ingrida Stankute, Diana Simoniene, Dovile Razanskaite-Virbickiene, Audrone Seibokaite, Brone Urbonaite, Nijole Jurgeviciene, Astra Vitkauskiene, Valerie Schwitzgebel, Dalia Marciulionyte
BACKGROUND: Initial classification of diabetes of young may require revision to improve diagnostic accuracy of different forms of diabetes. The aim of our study was to examine markers of beta-cell autoimmunity in a cohort of young (0-25 years) patients with type 1 diabetes and compare the presentation and course of the disease according to the presence of pancreatic antibodies. METHODS: Cross-sectional population-based study was performed covering 100% of pediatric (n = 860) and 70% of 18-25 years old adult patients (n = 349) with type 1 diabetes in Lithuania...
November 15, 2016: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/27828938/growth-and-body-mass-index-during-the-first-14-years-of-life-in-offspring-from-women-with-type-1-or-type-2-diabetes-mellitus
#13
Nurah M Hammoud, Harold W de Valk, Lenie van Rossem, Douwe H Biesma, Jan M Wit, Gerard H A Visser
BACKGROUNDInfants of women with pregestational diabetes are at risk for developing obesity in later life. This study aimed to identify subgroups at highest risk, by studying growth profiles of offspring from women with type 1 or 2 diabetes mellitus (ODM1, ODM2) until the age of 14 years.METHODSInformation from infant welfare centers was received for 78 ODM1 and 44 ODM2. Mean BMI standard deviation scores (SDS) (based on 1980 nation-wide references) and height SDS (based on 2009 references) were calculated and included in a random-effects model...
November 9, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27822115/danish-registry-of-childhood-and-adolescent-diabetes
#14
REVIEW
Jannet Svensson, Charlotte Cerqueira, Per Kjærsgaard, Lene Lyngsøe, Niels Thomas Hertel, Mette Madsen, Henrik B Mortensen, Jesper Johannesen
AIM: The aims of the Danish Registry of Childhood and Adolescent Diabetes (DanDiabKids) are to monitor and improve the quality of care for children and adolescents with diabetes in Denmark and to follow the incidence and prevalence of diabetes. STUDY POPULATION: The study population consists of all children diagnosed with diabetes before the age of 15 years since 1996. Since 2015, every child followed up at a pediatric center (<18 years of age) will be included...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27812509/type-1-diabetes-addressing-the-transition-from-pediatric-to-adult-oriented-health-care
#15
Maureen Monaghan, Katherine Baumann
Adolescents and young adults with type 1 diabetes are at risk for poor health outcomes, including poor glycemic control, acute and chronic complications, and emergency department admissions. During this developmental period, adolescent and young adult patients also experience significant changes in living situation, education, and/or health care delivery, including transferring from pediatric to adult health care. In recent years, professional and advocacy organizations have proposed expert guidelines to improve the process of preparation for and transition to adult-oriented health care...
2016: Research and Reports in Endocrine Disorders
https://www.readbyqxmd.com/read/27807935/type-2-diabetes-in-a-5-year-old-and-single-center-experience-of-type-2-diabetes-in-youth-under-10
#16
Jessica Hutchins, Rose Ann Barajas, Daniel Hale, Elia Escaname, Jane Lynch
The worrisome rise in pediatric type 2 diabetes (T2DM) is most prevalent among minority ethnic/racial populations. Typically, T2DM occurs during puberty in high risk obese adolescents with evidence of insulin resistance. Screening for T2DM in obese youth can be a daunting task for pediatricians and differentiating between pediatric T1DM and T2DM in obese youth can be challenging for pediatric endocrinologists. There is very limited data regarding the prevalence of T2DM among youth < 10 years of age...
November 3, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27807910/glargine-co-administration-with-intravenous-insulin-in-pediatric-diabetic-ketoacidosis-is-safe-and-facilitates-transition-to-a-subcutaneous-regimen
#17
V Sanoe Harrison, Stacy Rustico, Andrew A Palladino, Christine Ferrara, Colin Patrick Hawkes
BACKGROUND: Diabetes ketoacidosis (DKA) is a common presentation and complication of type 1 diabetes (T1D). While intravenous insulin is typically used to treat acute metabolic abnormalities, the transition from intravenous to subcutaneous treatment can present a challenge. We hypothesize that co-administration of glargine, a subcutaneous long-acting insulin analog, during insulin infusion may facilitate a flexible and safe transition from intravenous to subcutaneous therapy. OBJECTIVE: To determine if the practice of administering subcutaneous glargine during intravenous insulin is associated with an increased risk of hypoglycemia, hypokalemia, or other complications in children with DKA...
November 3, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27792712/-level-of-expression-of-gene-ctsl-and-its-correlation-with-natural-killer-t-cells-in-mexican-pediatric-patients-with-recent-onset-type-1-diabetes
#18
Rita Angélica Gómez-Díaz, Roberto Medina-Santillán, Blanca Elena Castro-Magdonel, Carolina Bekker-Méndez, Jaime Gómez-Zamudio, Elisa Nishimura-Meguro, Eulalia Garrido-Magaña, Lorena Lizárraga-Paulin, Blanca E Aguilar-Herrera, Adán Valladares-Salgado, Miguel Cruz, Rafael Mondragón-González, Vianney Ortiz-Navarrete, Niels H Wacher
OBJECTIVE: To compare the level of expression of the gene CTSL and its correlation with NKT cells in patients with recent-onset type 1 diabetes (T1D), their siblings, and healthy controls. METHODS: Analytical cross-sectional design. Patients with T1D < 3 months evolution, their siblings, and healthy controls were included. Percentages and absolute numbers of NKT cells were measured with expression of the CTSL gene. RESULTS: 124 subjects: with T1D (n = 48), siblings (n = 44) and controls (n = 32) were included...
October 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27788515/intrauterine-adiposity-and-bmi-in-4-to-5-year-old-offspring-from-diabetic-pregnancies
#19
Nurah M Hammoud, Harold W de Valk, Douwe H Biesma, Gerhard H A Visser
BACKGROUND: Pregnancies complicated by maternal diabetes are associated with disproportionate intrauterine growth that subsequently may lead to pediatric adiposity. OBJECTIVES: We investigated whether disproportionate intrauterine growth leads to differences in BMI in 4- to 5-year-old offspring from pregnancies complicated by type 1 (ODM1), type 2 (ODM2), or gestational diabetes (OGDM). METHODS: Ultrasound data of fetal head-to-abdominal circumference (HC/AC) ratio obtained between 32 and 36 weeks of gestational age were related to offspring anthropometrics that were retrieved from infant welfare centers...
October 28, 2016: Neonatology
https://www.readbyqxmd.com/read/27777901/excess-weight-gain-during-insulin-pump-therapy-is-associated-with-higher-basal-insulin-doses
#20
Claudia Boucher-Berry, Elaine A Parton, Ramin Alemzadeh
BACKGROUND: While higher total daily dose (TDD) of insulin has been associated with excess weight gain on insulin pump therapy, the role of higher total basal dose (TBD) of insulin on weight gain has not been studied. We evaluated the impact of higher TBD on weight gain in relationship to glycosylated hemoglobin (HbA1c), hypoglycemic episodes, and change in body mass index (BMI) z score in a group of pediatric patients with type 1 diabetes mellitus (T1DM). METHODS: One-year data from 91 (54 Female/37 Male) patients (2...
2016: Journal of Diabetes and Metabolic Disorders
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