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https://www.readbyqxmd.com/read/28350745/the-irish-helicobacter-pylori-working-group-consensus-for-the-diagnosis-and-treatment-of-h-pylori-infection-in-adult-patients-in-ireland
#1
Sinead Smith, Breida Boyle, Denise Brennan, Martin Buckley, Paul Crotty, Maeve Doyle, Richard Farrell, Mary Hussey, David Kevans, Peter Malfertheiner, Francis Megraud, Sean Nugent, Anthony O'Connor, Colm O'Morain, Shiobhan Weston, Deirdre McNamara
BACKGROUND: Irish eradication rates for Helicobacter pylori are decreasing and there is an increase in the prevalence of antibiotic-resistant bacteria. These trends call into question current management strategies. OBJECTIVE: To establish an Irish Helicobacter pylori Working Group (IHPWG) to assess, revise and tailor current available recommendations. METHODS: Experts in the areas of gastroenterology and microbiology were invited to join the IHPWG...
May 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28341284/prospective-microbiologic-evaluation-of-the-forceps-elevator-in-closed-channel-duodenoscopes-after-reprocessing
#2
Helga Paula, Barbara Tribl, Elisabeth Presterl, Magda Diab-El Schahawi
BACKGROUND: Endoscopes are well-known sources of bacterial transmission in health care facilities offering endoscopy services. The association between multidrug-resistant bacterial infections in patients who had undergone an endoscopic retrograde cholangiopancreatography procedure with reprocessed duodenoscopes has been much discussed. Bacterial contamination of duodenoscopes has been attributed to difficulties with reprocessing these devices, specifically the distal end of the scope, which features a movable forceps elevator...
February 1, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28340568/chronic-lymphocytic-leukemia-skin-infiltration-mimicking-an-icd-pocket-infection-a-case-report
#3
M Snorek, A Bulava, I Vonke
BACKGROUND: We are presenting a case report on an unreported and unusual cutaneous manifestation of chronic lymphocytic leukemia in a patient with an implantable cardioverter-defibrillator (ICD). CASE PRESENTATION: A 65-year-old man with a history of chronic lymphocytic leukemia (CLL), previously treated with chlorambucil, was referred in October 2013 for extraction of a single chamber ICD due to a suspected device-related infection in the pulse generator area (left-hand side of Fig...
March 24, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28335406/factors-that-negatively-affect-the-prognosis-of-pediatric-community-acquired-pneumonia-in-district-hospital-in-tanzania
#4
Serena Caggiano, Nicola Ullmann, Elisa De Vitis, Marzia Trivelli, Chiara Mariani, Maria Podagrosi, Fabiana Ursitti, Chiara Bertolaso, Carolina Putotto, Marta Unolt, Andrea Pietravalle, Paola Pansa, Kajoro Mphayokulela, Maria Incoronata Lemmo, Michael Mkwambe, Joseph Kazaura, Marzia Duse, Francesco Nieddu, Chiara Azzari, Renato Cutrera
Community-acquired pneumonia (CAP) is still the most important cause of death in countries with scarce resources. All children (33 months ± 35 DS) discharged from the Pediatric Unit of Itigi Hospital, Tanzania, with a diagnosis of CAP from August 2014 to April 2015 were enrolled. Clinical data were gathered. Dried blood spot (DBS) samples for quantitative real-time polymerase chain reaction (PCR) for bacterial detection were collected in all 100 children included. Twenty-four percent of patients were identified with severe CAP and 11% died...
March 13, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28334283/the-microbiology-of-oil-sands-tailings-past-present-future
#5
Julia M Foght, Lisa M Gieg, Tariq Siddique
Surface mining of enormous oil sands deposits in northeastern Alberta, Canada since 1967 has contributed greatly to Canada's economy but has also received negative international attention due largely to environmental concerns and challenges. Not only have microbes profoundly affected the composition and behaviour of this petroleum resource over geological time, they currently influence the management of semi-solid tailings in oil sands tailing ponds (OSTP) and tailings reclamation. Historically, microbial impacts on OSTP were generally discounted but next-generation sequencing and biogeochemical studies have revealed unexpectedly diverse indigenous communities and expanded our fundamental understanding of anaerobic microbial functions...
March 9, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/28331031/an-updated-systematic-review-and-meta-analysis-for-treatment-of-multidrug-resistant-tuberculosis
#6
Mayara Lisboa Bastos, Zhiyi Lan, Dick Menzies
This systematic review aimed to update the current evidence for multidrug-resistant tuberculosis (MDR-TB) treatment.We searched for studies that reported treatment information and clinical characteristics for at least 25 patients with microbiologically confirmed pulmonary MDR-TB and either end of treatment outcomes, 6-month culture conversion or severe adverse events (SAEs). We assessed the association of these outcomes with patients' characteristics or treatment parameters. We identified 74 studies, including 17 494 participants...
March 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28327524/reducing-risk-of-salmonellosis-through-egg-decontamination-processes
#7
REVIEW
Thilini Piushani Keerthirathne, Kirstin Ross, Howard Fallowfield, Harriet Whiley
Eggs have a high nutritional value and are an important ingredient in many food products. Worldwide foodborne illnesses, such as salmonellosis linked to the consumption of eggs and raw egg products, are a major public health concern. This review focuses on previous studies that have investigated the procedures for the production of microbiologically safe eggs. Studies exploring pasteurization and decontamination methods were investigated. Gamma irradiation, freeze drying, hot air, hot water, infra-red, atmospheric steam, microwave heating and radiofrequency heating are all different decontamination methods currently considered for the production of microbiologically safe eggs...
March 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28326754/supporting-imaging-modalities-for-improving-diagnosis-of-prosthesis-endocarditis-preliminary-results-of-a-single-center-experience-with-fluorine-18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#8
Anna Kokalova, Angelo M Dell'AQUILA, Nemanja Avramovic, Sven Martens, Christian Wenning, Jürgen R Sindermann
AIM: The aim of current study was to evaluate the role of PET-CT in the diagnosis of prosthetic valve endocarditis (PVE). METHODS: This is a single-center study including 13 PET/CT examinations performed between February 2009 and March 2016 in 13 patients (76.9% men, mean age 68.1 years, IQR 11.1) because of suspect of PVE. Median interval time between first operation and PET/CT examination was 19.02 months (lQR 85.5). Final diagnosis was made according to pathological criteria (histological and microbiological) of the Duke classification...
March 21, 2017: Minerva Medica
https://www.readbyqxmd.com/read/28323243/proteomics-of-facs-sorted-heterogeneous-corynebacterium-glutamicum-populations
#9
Andreas Harst, Stefan P Albaum, Tanja Bojarzyn, Christian Trötschel, Ansgar Poetsch
The metabolic status of individual cells in microbial cultures can differ, being relevant for biotechnology, environmental and medical microbiology. However, it is hardly understood in molecular detail due to limitations of current analytical tools. Here, we demonstrate that FACS in combination with proteomics can be used to sort and analyze cell populations based on their metabolic state. A previously established GFP reporter system was used to detect and sort single Corynebacterium glutamicum cells based on the concentration of branched chain amino acids (BCAA) using FACS...
March 17, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28322712/implementation-and-initial-analysis-of-a-laboratory-based-weekly-biosurveillance-system-provence-alpes-c%C3%A3-te-d-azur-france
#10
Michael Huart, Gabriel Bedubourg, Cédric Abat, Philippe Colson, Jean Marc Rolain, Hervé Chaudet, Pierre Edouard Fournier, Didier Raoult, Xavier Deparis
We describe the implementation of an automated infectious disease surveillance system that uses data collected from 210 microbiologic laboratories throughout the Provence-Alpes-Côte d'Azur region in France. Each week, these facilities report bacterial species that have been isolated from patients in their area. An alarm is triggered whenever the case count for a bacterial species infection exceeds 2 SDs of the historical mean for that species at the participating laboratory. At its inception in July 2013, the system monitored 611 bacterial species...
April 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28321788/characteristics-of-aerococcus-viridans-isolated-from-bovine-subclinical-mastitis-and-its-effect-on-milk-scc-yield-and-composition
#11
Meng Sun, Jian Gao, Tariq Ali, Dan Yu, Shiyao Zhang, Saeed U Khan, Séamus Fanning, Bo Han
Aerococcus viridians (A. viridans), an environmental Gram-positive bacterium, has been documented to be associated with bovine mastitis. However, its exact role in bovine mastitis and the changes it brings about in milk characteristics are not yet known. The objectives of the current study were to describe the antibiotic resistance of A. viridans from bovine mastitis as well as the correlation between existence of this pathogen in udders and the somatic cell counts (SCC), daily milk yield, and composition of individual cow...
March 20, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28317565/periodontal-microbiology
#12
REVIEW
John D Harvey
This article provides a review of current information about periodontal bacteria, their activities within dental plaque biofilm, their interactions with the host immune system, and the infections with which they are associated. Periodontal disease, plaque formation, and the host immune response are also discussed, as are antimicrobial measures used to control the bacteria and the disease.
April 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28316631/potential-impact-of-rapid-blood-culture-testing-for-gram-positive-bacteremia-in-japan-with-the-verigene-gram-positive-blood-culture-test
#13
Ken Kikuchi, Mari Matsuda, Shigekazu Iguchi, Tomonori Mizutani, Keiichi Hiramatsu, Michiru Tega-Ishii, Kaori Sansaka, Kenta Negishi, Kimie Shimada, Jun Umemura, Shigeyuki Notake, Hideji Yanagisawa, Hiroshi Takahashi, Reiko Yabusaki, Hideki Araoka, Akiko Yoneyama
Background. Early detection of Gram-positive bacteremia and timely appropriate antimicrobial therapy are required for decreasing patient mortality. The purpose of our study was to evaluate the performance of the Verigene Gram-positive blood culture assay (BC-GP) in two special healthcare settings and determine the potential impact of rapid blood culture testing for Gram-positive bacteremia within the Japanese healthcare delivery system. Furthermore, the study included simulated blood cultures, which included a library of well-characterized methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) isolates reflecting different geographical regions in Japan...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28306354/bronchiectasis-phenotyping-a-complex-disease
#14
James D Chalmers
Bronchiectasis is a long-neglected disease currently experiencing a surge in interest. It is a highly complex condition with numerous aetiologies, co-morbidities and a heterogeneous disease presentation and clinical course. The past few years have seen major advances in our understanding of the disease, primarily through large real-life cohort studies. The main outcomes of interest in bronchiectasis are symptoms, exacerbations, treatment response, disease progression and death. We are now more able to identify clearly the radiological, clinical, microbiological and inflammatory contributors to these outcomes...
March 15, 2017: COPD
https://www.readbyqxmd.com/read/28303449/novel-beta-lactamase-inhibitors-unlocking-their-potential-in-therapy
#15
Darren Wong, David van Duin
Carbapenem-resistant Enterobacteriaceae are amongst the most feared pathogens due to severely limited treatment options. In response to this threat, three novel β-lactamase inhibitors have been developed in an attempt to reinvigorate and sustain our current antimicrobial therapies. Avibactam, vaborbactam, and relebactam are inhibitor agents with high affinity to Ambler class A and C β-lactamases and favorable outcomes in current clinical trials. However, although they do possess key similarities, these agents have unique differences which may have important clinical implications...
March 16, 2017: Drugs
https://www.readbyqxmd.com/read/28303131/multiplexed-single-intact-cell-droplet-digital-pcr-music-ddpcr-method-for-specific-detection-of-enterohemorrhagic-e-coli-ehec-in-food-enrichment-cultures
#16
Tanis C McMahon, Burton W Blais, Alex Wong, Catherine D Carrillo
Foodborne illness attributed to enterohemorrhagic E. coli (EHEC), a highly pathogenic subset of Shiga toxin-producing E. coli (STEC), is increasingly recognized as a significant public health issue. Current microbiological methods for identification of EHEC in foods often use PCR-based approaches to screen enrichment broth cultures for characteristic gene markers [i.e., Shiga toxin (stx) and intimin (eae)]. However, false positives arise when complex food matrices, such as beef, contain mixtures of eae-negative STEC and eae-positive E...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28299183/challenges-in-microbiological-diagnosis-of-invasive-aspergillus-infections
#17
REVIEW
Alexandre Alanio, Stéphane Bretagne
Invasive aspergillosis (IA) has been increasingly reported in populations other than the historical hematology patients and there are new questions about the performance of microbiological tools. Microscopy and culture have been completed by biomarkers, either antigens or DNA, and in blood or respiratory specimens or both. First studied in hematology, the antigen galactomannan performance in serum is low in other patient populations where the pathophysiology of the infection can be different and the prevalence of IA is much lower...
2017: F1000Research
https://www.readbyqxmd.com/read/28292540/reactive-arthritis
#18
REVIEW
Steven K Schmitt
Reactive arthritis is classified as a spondyloarthropathy. Current concepts of disease suggest an infectious trigger, followed by inflammatory arthritis. Several mechanisms have been proposed to explain the interaction of host susceptibility and microorganism. Diagnosis relies on a compatible clinical syndrome and microbiologic confirmation of the pathogen. Antibiotic therapy seems useful in Chlamydia-triggered arthritis. The role of antibiotics in arthritis triggered by enteric pathogens is less clear. The role of tumor necrosis factor alpha inhibitors in therapy is evolving...
March 11, 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28279880/electrobioremediation-of-oil-spills
#19
REVIEW
Matteo Daghio, Federico Aulenta, Eleni Vaiopoulou, Andrea Franzetti, Jan B A Arends, Angela Sherry, Ana Suárez-Suárez, Ian M Head, Giuseppina Bestetti, Korneel Rabaey
Annually, thousands of oil spills occur across the globe. As a result, petroleum substances and petrochemical compounds are widespread contaminants causing concern due to their toxicity and recalcitrance. Many remediation strategies have been developed using both physicochemical and biological approaches. Biological strategies are most benign, aiming to enhance microbial metabolic activities by supplying limiting inorganic nutrients, electron acceptors or donors, thus stimulating oxidation or reduction of contaminants...
February 20, 2017: Water Research
https://www.readbyqxmd.com/read/28275370/pbhmda-path-based-human-microbe-disease-association-prediction
#20
Zhi-An Huang, Xing Chen, Zexuan Zhu, Hongsheng Liu, Gui-Ying Yan, Zhu-Hong You, Zhenkun Wen
With the advance of sequencing technology and microbiology, the microorganisms have been found to be closely related to various important human diseases. The increasing identification of human microbe-disease associations offers important insights into the underlying disease mechanism understanding from the perspective of human microbes, which are greatly helpful for investigating pathogenesis, promoting early diagnosis and improving precision medicine. However, the current knowledge in this domain is still limited and far from complete...
2017: Frontiers in Microbiology
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