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https://www.readbyqxmd.com/read/28542614/evaluation-of-the-sepsis-flow-chip-assay-for-the-diagnosis-of-blood-infections
#1
Antonio Galiana, Javier Coy, Adelina Gimeno, Noemi Marco Guzman, Francisco Rosales, Esperanza Merino, Gloria Royo, Juan Carlos Rodríguez
BACKGROUND: Blood infections are serious complex conditions that generally require rapid diagnosis and treatment. The big challenge is to reduce the time necessary to make a diagnosis with current clinical microbiological methods so as to improve the treatment given to patients. METHODS: In this study, we assess for the first time the Sepsis Flow Chip assay, which is a novel diagnostic assay for simultaneous rapid-detection of the vast majority of bloodstream pathogens, including Gram-positive and Gram-negative bacteria and fungi, in the same assay, and for the detection of most common antibiotic resistance genes...
2017: PloS One
https://www.readbyqxmd.com/read/28542286/clinical-impact-of-chronic-obstructive-pulmonary-disease-on-non-cystic-fibrosis-bronchiectasis-a-study-on-1-790-patients-from-the-spanish-bronchiectasis-historical-registry
#2
David De la Rosa, Miguel-Angel Martínez-Garcia, Rosa Maria Giron, Montserrat Vendrell, Casilda Olveira, Luis Borderias, Luis Maiz, Antoni Torres, Eva Martinez-Moragon, Olga Rajas, Francisco Casas, Rosa Cordovilla, Javier de Gracia
BACKGROUND: Few studies have evaluated the coexistence of bronchiectasis (BE) and chronic obstructive pulmonary disease (COPD) in series of patients diagnosed primarily with BE. The aim of this study was to analyse the characteristics of patients with BE associated with COPD included in the Spanish Bronchiectasis Historical Registry and compare them to the remaining patients with non-cystic fibrosis BE. METHODS: We conducted a multicentre observational study of historical cohorts, analysing the characteristics of 1,790 patients who had been included in the registry between 2002 and 2011...
2017: PloS One
https://www.readbyqxmd.com/read/28540567/-the-significance-of-biofilm-for-the-treatment-of-infections-in-orthopedic-surgery-2017-update
#3
REVIEW
C Scheuermann-Poley, C Wagner, J Hoffmann, A Moter, C Willy
BACKGROUND: The increase in endoprosthetic and osteosynthetic surgical treatment is associated with a simultaneous increase in implant-associated infections (surgical site infections, SSI). Biofilms appear to play a significant role in the diagnosis and treatment of these infections and heavily contaminated wounds. This article aims to provide a current overview of biofilm and its relevance in orthopedic surgery. MATERIALS AND METHODS: A computer-assisted literature search of MedLine (PubMed) was performed using key word combinations with "biofilm" (as of March 2017)...
May 24, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28540556/the-use-of-bacterial-bioremediation-of-metals-in-aquatic-environments-in-the-twenty-first-century-a-systematic-review
#4
Feliphe Lacerda Souza de Alencar, Julio Alejandro Navoni, Viviane Souza do Amaral
Metal pollution is a current environmental issue as a consequence of unregulated anthropic activiy. A wide range of bioremediation strategies have been successfully implemented to recover contaminated areas. Among them, bacterial bioremediation stands out as a promising tool to confront these types of concerns. This study aimed to compare and discuss worldwide scientific evolution of bacterial potential for metal bioremediation in aquatic ecosystems. The study consisted of a systematic review, elaborated through a conceptual hypothesis model, during the period from 2000 to 2016, using PubMed, MEDLINE, and SciELO databases as data resources...
May 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28539920/technological-microbiology-development-and-applications
#5
REVIEW
Luciana C Vitorino, Layara A Bessa
Over thousands of years, modernization could be predicted for the use of microorganisms in the production of foods and beverages. However, the current accelerated pace of new food production is due to the rapid incorporation of biotechnological techniques that allow the rapid identification of new molecules and microorganisms or even the genetic improvement of known species. At no other time in history have microorganisms been so present in areas such as agriculture and medicine, except as recognized villains...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28538501/invasive-pneumococcal-disease-in-patients-with-sickle-cell-disease
#6
Pournima Navalkele, Bülent Özgönenel, Eric McGrath, Paul Lephart, Sharada Sarnaik
BACKGROUND: Patients with sickle cell disease (SCD) are at risk of fatal sepsis with encapsulated bacteria, such as Streptococcus pneumoniae, because of the inherent autosplenectomy that occurs in SCD. This risk is thwarted with oral penicillin prophylaxis during the first 5 years of life, and with stringent vaccination against S. pneumoniae alongside routine childhood immunization. But compared with the general African American pediatric population, the rate of invasive pneumococcal disease (IPD) in patients with SCD still remains high, resulting in hospitalization and fatality...
May 22, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28538238/current-research-on-the-epidemiology-pathogenesis-and-management-of-necrotizing-enterocolitis
#7
Simon Eaton, Clare M Rees, Nigel J Hall
Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm infants and infants with necrotizing enterocolitis, there is some hope that research into this devastating disease will yield some important translation into effective prevention, more rapid diagnosis, and novel therapies...
2017: Neonatology
https://www.readbyqxmd.com/read/28533857/antibiogram-profile-of-uropathogens-isolated-at-bahir-dar-regional-health-research-laboratory-centre-northwest-ethiopia
#8
Awoke Derbie, Derese Hailu, Daniel Mekonnen, Bayeh Abera, Gashaw Yitayew
INTRODUCTION: Antimicrobial resistance among bacteria that cause urinary tract infection (UTI) has been increasing since the introduction of chemotherapy. This study was aimed to assess the types of isolates from patients with UTI and to determine their current antimicrobial susceptibility profile. METHODS: A record based retrospective analysis of bacterial uropathogens processed in the period of January 2012 to December 2014 at Bahir Dar Health Research Laboratory Center (BRHRLC) was determined...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28529027/management-of-postneurosurgical-meningitis-narrative-review
#9
REVIEW
Khetam Hussein, Roni Bitterman, Ben Shofty, Mical Paul, Ami Neuberger
BACKGROUND: Infections complicating neurosurgery pose unacceptable mortality and morbidity. AIMS: To summarize what is known about the epidemiology, diagnosis and treatment of post-neurosurgical meningitis (PNM). SOURCES: PubMed, references of identified studies and reviews, and personal experience when evidence was lacking. CONTENT: The incidence and pathogen distribution of PNM is highly variable. A shift towards Gram-negative bacteria has been observed with use of antibiotic prophylaxis and antibiotic-coated devices directed mainly against Gram-positive bacteria...
May 18, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28527363/postmortem-microbial-communities-in-burial-soil-layers-of-skeletonized-humans
#10
Torri B Thomas, Sheree J Finley, Jeremy E Wilkinson, Daniel J Wescott, Azriel Gorski, Gulnaz T Javan
Microorganisms are major ecological participants in the successional decomposition of vertebrates. The relative abundance, or the scarcity, of certain microbial taxa in gravesoil has the potential to determine the ecological status of skeletons. However, there are substantial knowledge gaps that warrant consideration in the context of the surrounding terrestrial ecosystem. In the current study, we hypothesized that i.) soil microbial diversity is disparate in the latter stage of decomposition (skeletonization) compared to the earlier stages (fresh, bloat, active and advanced decay), and ii...
May 3, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28520995/new-molecular-diagnostic-tools-in-traveller-s-diarrhea
#11
Jordi Vila
Traveller's diarrhea can be caused by bacteria, protozoa, helminths and viruses. Globally, the most common causes of traveller's diarrhea are two pathotypes of Escherichia coli (enterotoxigenic and enteroaggregative) and Shigella, although there are significant variations according to the geographic area visited. While traveller's diarrhea is usually a mild, self-limiting disease, half of the travellers with traveller's diarrhea have some limitation in their activities during the journey and up to 10% present persistent diarrhea or other complications, making microbiological diagnosis necessary...
April 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28518194/detection-of-antibiotic-resistant-escherichia-coli-bacteria-using-infrared-microscopy-and-advanced-multivariate-analysis
#12
Ahmad Salman, Uraib Sharaha, Eladio Rodriguez-Diaz, Elad Shufan, Klaris Riesenberg, Irving J Bigio, Mahmoud Huleihel
Bacterial resistance to antibiotics is becoming a global health-care problem. Bacteria are involved in many diseases, and antibiotics have been the most effective treatment for them. It is essential to treat an infection with an antibiotic to which the infecting bacteria is sensitive; otherwise, the treatment is not effective and may lead to life-threatening progression of disease. Classical microbiology methods that are used for determination of bacterial susceptibility to antibiotics are time consuming, accounting for problematic delays in the administration of appropriate drugs...
May 18, 2017: Analyst
https://www.readbyqxmd.com/read/28516820/blogging-in-infectious-diseases-and-clinical-microbiology-assessment-of-blogosphere-content
#13
Gabriel Birgand, Rachael Troughton, Luke S P Moore, Esmita Charani, Timothy M Rawson, Enrique Castro-Sánchez, Alison H Holmes
OBJECTIVE To analyze influential infectious diseases, antimicrobial stewardship, infection control, or medical microbiology blogs and bloggers SETTING World wide web DESIGN We conducted a systematic search for blogs in accordance with the PRISMA guidelines in September 2015. METHODS A snowball sampling approach was applied to identify blogs using various search engines. Blogs were eligible if they (1) focused on infectious diseases, antimicrobial stewardship, infection control, or medical microbiology; (2) were intended for health professionals; and (3) were written in English and (4) were updated regularly...
May 18, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28513150/production-of-caproic-acid-from-mixed-organic-waste-an-environmental-life-cycle-perspective
#14
Wei-Shan Chen, David P B T B Strik, Cees J N Buisman, Carolien Kroeze
Caproic acid is an emerging platform chemical with diverse applications. Recently, a novel biorefinery process, that is, chain elongation, was developed to convert mixed organic waste and ethanol into renewable caproic acids. In the coming years, this process may become commercialized, and continuing to improve on the basis of numerous ongoing technological and microbiological studies. This study aims to analyze the environmental performance of caproic acid production from mixed organic waste via chain elongation at this current, early stage of technological development...
May 26, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28504926/accurate-differentiation-of-mycobacterium-chimaera-from-mycobacterium-intracellulare-by-maldi-tof-ms-analysis
#15
Arthur B Pranada, Ellen Witt, Michael Bienia, Markus Kostrzewa, Markus Timke
PURPOSE: The increasing number of infections caused by nontuberculous mycobacteria (NTM) has prompted the need for rapid and precise identification methods of these pathogens. Several studies report the applicability of MALDI-TOF mass spectrometry (MS) for identification of NTM. However, some closely related species have very similar spectral mass fingerprints, and until recently, Mycobacterium chimaera and M. intracellulare could not be separated from each other by MALDI-TOF MS. METHODOLOGY: The conventional identification methods used in routine diagnostics have similar limitations...
May 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28504899/metabolic-diversity-and-novelties-in-the-oomycetes
#16
Howard S Judelson
The eukaryotic microbes called oomycetes include many important saprophytes and pathogens, with the latter exhibiting necrotrophy, biotrophy, or obligate biotrophy. Understanding oomycete metabolism is fundamental to understanding these lifestyles. Genome mining and biochemical studies have shown that oomycetes, which belong to the kingdom Stramenopila, secrete suites of carbohydrate- and protein-degrading enzymes adapted to their environmental niches and produce unusual lipids and energy storage compounds...
May 15, 2017: Annual Review of Microbiology
https://www.readbyqxmd.com/read/28504240/maldi-tof-ms-in-the-microbiology-laboratory-current-trends
#17
Sören Schubert, Markus Kostrzewa
Within less than a decade matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has become a gold standard for microbial identification in clinical microbiology laboratories. Besides identification of microorganisms the typing of single strains as well as the antibiotic and antimycotic resistance testing has come into focus in order to speed up the microbiological diagnostic. However, the full potential of MALDI-TOF MS has not been tapped yet and future technological advancements will certainly expedite this method towards novel applications and enhancement of current practice...
May 15, 2017: Current Issues in Molecular Biology
https://www.readbyqxmd.com/read/28503338/infrarenal-infected-aortic-aneurysm-caused-by-streptococcus-pyogenes
#18
Floryn Cherbanyk, Markus Menth, Bernhard Egger, Véronique Erard
Infectious aneurysm is a rare entity associated with significant morbidity and mortality. Current knowledge on pathogenesis, outcome, diagnosis, management, and follow-up remains debatable. We report the case of a patient with Streptococcus pyogenes aneurysm who was successfully treated with a homograft implant and discuss microbiological characteristics, diagnostic methods, and treatment options currently available for this serious disease.
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28501669/an-update-on-bacterial-brain-abscess-in-immunocompetent-patients
#19
REVIEW
R Sonneville, R Ruimy, N Benzonana, L Riffaud, A Carsin, J-M Tadié, C Piau, M Revest, P Tattevin
BACKGROUND: Brain abscess is a focal infection of the brain, that begins as a localized area of cerebritis. In immunocompetent patients, bacteria are responsible for >95% of brain abscess, and enter the brain either through contiguous spread following otitis, sinusitis, neurosurgery, or cranial trauma, or through hematogenous dissemination. AIMS: To identify recent advents in the field. Sources We searched Medline and Embase for articles published during years 2012-2016, with the keywords 'brain', and 'abscess'...
May 10, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28496434/a-critical-assessment-of-the-microorganisms-proposed-to-be-important-to-enhanced-biological-phosphorus-removal-in-full-scale-wastewater-treatment-systems
#20
Mikkel Stokholm-Bjerregaard, Simon J McIlroy, Marta Nierychlo, Søren M Karst, Mads Albertsen, Per H Nielsen
Understanding the microbiology of phosphorus (P) removal is considered essential to knowledge-based optimization of enhanced biological P removal (EBPR) systems. Biological P removal is achieved in these systems by promoting the growth of organisms collectively known as the polyphosphate accumulating organisms (PAOs). Also considered important to EBPR are the glycogen accumulating organisms (GAOs), which are theorized to compete with the PAOs for resources at the expense of P removal efficiency. Numerous studies have sought to identify the PAOs and their GAOs competitors, with several candidates proposed for each over the last few decades...
2017: Frontiers in Microbiology
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