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https://www.readbyqxmd.com/read/29447029/nanosilver-and-the-microbiological-activity-of-the-particulate-solids-versus-the-leached-soluble-silver
#1
Merisa B Faiz, Rose Amal, Christopher P Marquis, Elizabeth J Harry, Georgios A Sotiriou, Scott A Rice, Cindy Gunawan
Nanosilver (Ag NPs) is currently one of the most commercialized antimicrobial nanoparticles with as yet, still unresolved cytotoxicity origins. To date, research efforts have mostly described the antimicrobial contribution from the leaching of soluble silver, while the undissolved solid Ag particulates are often considered as being microbiologically inert, serving only as source of the cytotoxic Ag ions. Here, we show the rapid stimulation of lethal cellular oxidative stress in bacteria by the presence of the undissolved Ag particulates...
February 15, 2018: Nanotoxicology
https://www.readbyqxmd.com/read/29441201/leech-management-before-application-on-patient-a-nationwide-survey-of-practices-in-french-university-hospitals
#2
Delphine Grau, Raphaël Masson, Maxime Villiet, Brigitte Lamy
Background: Leech therapy in plastic/reconstructive microsurgery significantly improves a successful outcome of flap salvage but the drawback is a risk of severe infection that results in a drop of the salvage rates from 70-80% to below 30%. We report the results of a national survey conducted in all the French university hospitals to assess the current extent of use of leech for medical practices in the hospital and to investigate maintenance, delivery practices and prevention of the risk of infection...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29433799/international-survey-among-orthopaedic-trauma-surgeons-lack-of-a-definition-of-fracture-related-infection
#3
M Morgenstern, T F Moriarty, R Kuehl, R G Richards, M A McNally, M H J Verhofstad, O Borens, C Zalavras, M Raschke, S L Kates, W J Metsemakers
INTRODUCTION: Fracture-related infection (FRI) is one of the most challenging musculoskeletal complications in orthopaedic-trauma surgery. Although the orthopaedic community has developed and adopted a consensus definition of prosthetic joint infections (PJI), it still remains unclear how the trauma surgery community defines FRI in daily clinical practice or in performing clinical research studies. The central aim of this study was to survey the opinions of a global network of trauma surgeons on the definitions and criteria they routinely use, and their opinion on the need for a unified definition of FRI...
February 6, 2018: Injury
https://www.readbyqxmd.com/read/29427686/laboratory-diagnosis-of-urinary-tract-infections-towards-a-bilulu-consensus-guideline
#4
REVIEW
Matthijs Oyaert, Britt Van Meensel, Reinoud Cartuyvels, Johan Frans, Wim Laffut, Patricia Vandecandelaere, Hans De Beenhouwer
The BILULU study group consists of seven microbiologists of hospital laboratories located in the region of Flanders (Belgium). A major goal of the group is to standardize diagnostic microbiology procedures based on available evidence and, in the absence of evidence, based on general microbiological principles and expert opinion. Scientific evidence of current urine culture guidelines is incomplete and at some points guidelines don't indicate clear choice. The aim of this project was to develop a clear and unambiguous step-by-step guideline regarding the work-up of urine cultures...
February 7, 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29423421/an-updated-review-of-iclaprim-a-potent-and-rapidly-bactericidal-antibiotic-for-the-treatment-of-skin-and-skin-structure-infections-and-nosocomial-pneumonia-caused-by-gram-positive-including-multidrug-resistant-bacteria
#5
REVIEW
David B Huang, Catherine D Strader, James S MacDonald, Mark VanArendonk, Richard Peck, Thomas Holland
New antibiotics are needed because of the increased morbidity and mortality associated with multidrug-resistant bacteria. Iclaprim, a bacterial dihydrofolate reductase inhibitor, not currently approved, is being studied for the treatment of skin infections and nosocomial pneumonia caused by Gram-positve bacteria, including multidrug-resistant bacteria. Iclaprim showed noninferiority at -10% to linezolid in 1 of 2 phase 3 studies for the treatment of complicated skin and skin structure infections with a weight-based dose (0...
February 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29419793/microbiological-values-of-rainwater-harvested-in-adelaide
#6
Chirhakarhula Emmanuel Chubaka, Harriet Whiley, John W Edwards, Kirstin E Ross
In Australia, rainwater is an important source of water for many households. Unlike municipal water, rainwater is often consumed untreated. This study investigated the potential contamination of rainwater by microorganisms. Samples from 53 rainwater tanks across the Adelaide region were collected and tested using Colilert™ IDEXX Quanti-Tray*/2000. Twenty-eight out of the 53 tanks (53%) contained Escherichia coli. Samples collected from ten tanks contained E. coli at concentrations exceeding the limit of 150 MPN/100 mL for recreational water quality...
February 8, 2018: Pathogens
https://www.readbyqxmd.com/read/29410162/microbiological-outcome-of-interventions-against-pulmonary-mac-disease-a-systematic-review
#7
R Diel, A Nienhaus, F Ringshausen, E Richter, T Welte, K F Rabe, R Loddenkemper
OBJECTIVE: Pulmonary disease (PD) caused by Mycobacterium avium complex (MAC) is increasing worldwide. We conducted a systematic review of studies that include microbiological outcomes to evaluate current macrolide-based treatment regimens. METHODS: We searched literature published before April 2017 using MEDLINE, Cochrane, and EMBASE databases. Risk of bias in randomized trials was assessed using the Cochrane tool. RESULTS: 333 citations were retrieved and 42 studies including 2748 patients evaluated...
February 1, 2018: Chest
https://www.readbyqxmd.com/read/29405111/case-report-misleading-serological-diagnosis-of-paracoccidioidomycosis-in-a-young-patient-with-the-acute-form-disease-paracoccidioides-brasiliensis-or-paracoccidioides-lutzii
#8
Renata Buccheri, Vanessa Dos Santos Moraes, Camila Mika Kamikawa, Monica Scarpelli Martinelli Vidal, Gabriel Naves, Gilda Maria Barbaro Del Negro, Adriana Pardini Vicentini, Gil Benard
Negative results in serological routine screening of patients with microbiologically proven PCM are occasionally reported. Failure in detecting anti-Paracoccidioides antibodies has been ascribed to factors either related to serological techniques or to the status of the host immune reactivity. Recently, this issue has been renewed by the recognition that the Paracoccidioides genera comprises two species, lutzii and brasiliensis, which have distinct antigenic profiles and, therefore, may elicit different host antibody responses...
February 5, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29404836/characterization-of-the-nasopharyngeal-and-middle-ear-microbiota-in-gastroesophageal-reflux-prone-versus-gastroesophageal-reflux-non-prone-children
#9
Stefan A Boers, Marjolein de Zeeuw, Ruud Jansen, Marc P van der Schroeff, Annemarie M C van Rossum, John P Hays, Suzanne J C Verhaegh
Otitis media (OM) is one of the most common pediatric infections worldwide, but the complex microbiology associated with OM is poorly understood. Previous studies have shown an association between OM and gastroesophageal reflux (GER) in children. Therefore, in order to bridge the gap in our current understanding of the interaction between GER and OM, we investigated the nasopharyngeal and middle ear microbiota of children suffering from GER-associated OM and OM only, using culture-independent 16S rRNA gene sequencing...
February 5, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29403461/stripping-away-the-soil-plant-growth-promoting-microbiology-opportunities-in-aquaponics
#10
Ryan P Bartelme, Ben O Oyserman, Jesse E Blom, Osvaldo J Sepulveda-Villet, Ryan J Newton
As the processes facilitated by plant growth promoting microorganisms (PGPMs) become better characterized, it is evident that PGPMs may be critical for successful sustainable agricultural practices. Microbes enrich plant growth through various mechanisms, such as enhancing resistance to disease and drought, producing beneficial molecules, and supplying nutrients and trace metals to the plant rhizosphere. Previous studies of PGPMs have focused primarily on soil-based crops. In contrast, aquaponics is a water-based agricultural system, in which production relies upon internal nutrient recycling to co-cultivate plants with fish...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29402488/-clinical-and-microbiological-profile-of-patients-experiencing-relapses-of-tuberculosis-in-tunisia
#11
M Mjid, A Hedhli, M Zakhma, M Zribi, Y Ouahchi, S Toujani, J Cherif
INTRODUCTION: Relapse of tuberculosis (TB) is known to be as one of the major risk factors for resistant TB. The aim of this study is to focus on clinical, radiological and bacteriological features of patients with pulmonary TB relapse. METHODS: We performed a retrospective survey in the respiratory department of the teaching hospital La Rabta in Tunis between January 2000 and December 2014. Data of patients with a pulmonary TB relapse were analyzed. RESULTS: During the study period, among 1250 patients hospitalized for pulmonary TB, 44 had a TB relapse...
February 2, 2018: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/29391695/isolation-and-identification-of-a-cellulolytic-enterobacter-from-rumen-of-aceh-cattle
#12
Wenny Novita Sari, Safika, Darmawi, Yudha Fahrimal
Aims: The aim of this study was to isolate and identify a cellulolytic bacterium from the rumen fluid of Aceh's cattle. Biodegradation by cellulolytic rumen bacteria can be used as a source of cellulolytic bacteria that act to degrade feed fibrous material so as to improve the quality of nutrients and digestibility of feed ingredients at a cheaper price than the use of commercial cellulase enzymes. Materials and Methods: Samples were collected from rumen fluid of Aceh's cattle in Abattoirs (RPH) of Banda Aceh city, Indonesia, isolation, and screening of cellulolytic bacteria were done in Microbiology Laboratory, Faculty of Veterinary Medicine, Syiah Kuala University, Banda Aceh, Indonesia...
December 2017: Veterinary World
https://www.readbyqxmd.com/read/29389843/adoptable-interventions-human-health-and-food-safety-considerations-for-reducing-sodium-content-of-processed-food-products
#13
Abimbola Allison, Aliyar Fouladkhah
Although vital for maintaining health when consumed in moderation, various epidemiological studies in recent years have shown a strong association between excess dietary sodium with an array of health complications. These associations are robust and clinically significant for development of hypertension and prehypertension, two of the leading causes of preventable mortality worldwide, in adults with a high-sodium diet. Data from developed nations and transition economies show worldwide sodium intake of higher than recommended amounts in various nations...
February 1, 2018: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/29388184/imaging-the-unimaginable-desorption-electrospray-ionization-imaging-mass-spectrometry-desi-ims-in-natural-product-research
#14
Delphine Parrot, Stefano Papazian, Daniel Foil, Deniz Tasdemir
Imaging mass spectrometry (IMS) has recently established itself in the field of "spatial metabolomics." Merging the sensitivity and fast screening of high-throughput mass spectrometry with spatial and temporal chemical information, IMS visualizes the production, location, and distribution of metabolites in intact biological models. Since metabolite profiling and morphological features are combined in single images, IMS offers an unmatched chemical detail on complex biological and microbiological systems. Thus, IMS-type "spatial metabolomics" emerges as a powerful and complementary approach to genomics, transcriptomics, and classical metabolomics studies...
January 31, 2018: Planta Medica
https://www.readbyqxmd.com/read/29387826/the-prevalence-of-and-risk-factors-for-mycoplasma-genitalium-infection-among-infertile-women-in-ibadan-a-cross-sectional-study
#15
Tinuade Adesola Ajani, Timothy A Olusesan Oluwasola, Mustapha A Ajani, Rasheed Ajani Bakare
Background: The association of mycoplasma genitalium (M. genitalium) with infertility has been documented. The infections are asymptomatic and difficult to diagnose. Understanding the associated risk factors will help in facilitating better screening measures for at-risk groups. Objective: The aim was to determine the prevalence of, and risk factors for, M. genitalium infection among infertile women in Ibadan. Materials and Methods: In this cross-sectional study, 402 women (267 infertile and 135 fertile) referred to 2 hospitals in Ibadan between March and November 2015 were enrolled...
October 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29383667/european-practice-for-cdi-treatment
#16
Fidelma Fitzpatrick, Mairead Skally, Melissa Brady, Karen Burns, Christopher Rooney, Mark H Wilcox
Clostridium difficile infection (CDI) remains a significant cause of morbidity and mortality worldwide. Historically, two antibiotics (metronidazole and vancomycin) and a recent third (fidaxomicin) have been used routinely for CDI treatment; convincing data are now available showing that metronidazole is the least efficacious agent. The European Society of Clinical Microbiology and Infectious Diseases CDI treatment guidelines outline the treatment options for a variety of CDI clinical scenarios, including use of the more traditional anti-CDI therapies (e...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29383456/continuous-culture-techniques-as-simulators-for-standard-cells-jacques-monod-s-aron-novick-s-and-leo-szilard-s-quantitative-approach-to-microbiology
#17
Gabriele Gramelsberger
Continuous culture techniques were developed in the early twentieth century to replace cumbersome studies of cell growth in batch cultures. In contrast to batch cultures, they constituted an open concept, as cells are forced to proliferate by adding new medium while cell suspension is constantly removed. During the 1940s and 1950s new devices have been designed-called "automatic syringe mechanism," "turbidostat," "chemostat," "bactogen," and "microbial auxanometer"-which allowed increasingly accurate quantitative measurements of bacterial growth...
January 30, 2018: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/29383395/bacterial-sepsis-diagnostics-and-calculated-antibiotic-therapy
#18
REVIEW
D C Richter, A Heininger, T Brenner, M Hochreiter, M Bernhard, J Briegel, S Dubler, B Grabein, A Hecker, W A Kruger, K Mayer, M W Pletz, D Storzinger, N Pinder, T Hoppe-Tichy, S Weiterer, S Zimmermann, A Brinkmann, M A Weigand, C Lichtenstern
The mortality of patients with sepsis and septic shock is still unacceptably high. An effective calculated antibiotic treatment within 1 h of recognition of sepsis is an important target of sepsis treatment. Delays lead to an increase in mortality; therefore, structured treatment concepts form a rational foundation, taking relevant diagnostic and treatment steps into consideration. In addition to the assumed infection and individual risks of each patient, local resistance patterns and specific problem pathogens must be taken into account during the selection of anti-infective treatment...
January 30, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/29382396/higher-cut-off-serum-procalcitonin-level-for-sepsis-diagnosis-in-metastatic-solid-tumor-patients
#19
Segal Abdul Aziz, Erni Juwita Nelwan, Lugyanti Sukrisman, Suhendro Suhendro
OBJECTIVE: The current study aimed to know procalcitonin levels in patients with metastatic tumor, and to discover the cut-off point for sepsis in this population. A cross-sectional study was conducted with patients with solid tumor. Sepsis and systemic inflammation response syndrome (SIRS) were identified using clinical, laboratory, and microbiological criteria. The cut-off point was determined using receiver operating characteristic (ROC) curve. RESULTS: A total of 112 subjects enrolled in this study, 51% male, mean age 47...
January 30, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29381714/extended-spectrum-beta-lactamase-esbl-producing-escherichia-coli-and-acinetobacter-baumannii-among-horses-entering-a-veterinary-teaching-hospital-the-contemporary-trojan-horse
#20
Birgit Walther, Katja-Sophia Klein, Ann-Kristin Barton, Torsten Semmler, Charlotte Huber, Silver Anthony Wolf, Karsten Tedin, Roswitha Merle, Franziska Mitrach, Sebastian Guenther, Antina Lübke-Becker, Heidrun Gehlen
Pathogens frequently associated with multi-drug resistant (MDR) phenotypes, including extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) and Acinetobacter baumannii isolated from horses admitted to horse clinics, pose a risk for animal patients and personnel in horse clinics. To estimate current rates of colonization, a total of 341 equine patients were screened for carriage of zoonotic indicator pathogens at hospital admission. Horses showing clinical signs associated with colic (n = 233) or open wounds (n = 108) were selected for microbiological examination of nostril swabs, faecal samples and wound swabs taken from the open wound group...
2018: PloS One
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