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https://www.readbyqxmd.com/read/28214018/assessment-of-root-canal-filling-removal-effectiveness-using-micro-computed-tomography-a-systematic-review
#1
REVIEW
Giampiero Rossi-Fedele, Hany Mohamed Aly Ahmed
INTRODUCTION: The removal of obturation materials from the root canal system is a primary objective in root canal retreatment procedures. This systematic review aims to discuss the effectiveness of different instrumentation procedures in removing root-canal filling materials assessed by micro-computed tomography. METHODS: An electronic search in PubMed and major endodontic journals was conducted using appropriate key words to identify investigations that examined the effectiveness of obturation material removal assessed by micro-computed tomography...
February 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28213245/one-pot-synthesis-of-gold-carbon-dots-nanocomposite-and-its-application-for-cytosensing-of-metals-for-cancer-cells
#2
Hani Nasser Abdelhamid, Abuo Talib, Hui-Fen Wu
Cytosensing of biological transition metals is paramount important for cancer research. One-pot synthesis of the nanocomposite of carbon dots (CDs) and gold nanoparticles (AuNPs) is reported and has been applied for metal cytosensing. The nanocomposite (GCDs) is synthesized using citric acid (CA) and L-cysteine as precursors in the presence of chloroauric acid. The synthesis procedure exhibits many advantages including simple one step, green approach (solvent free method) and requires cheap chemical precursors...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28212261/passage-of-gallstones-into-common-bile-duct-during-laparoscopic-cholecystectomy-is-it-surgeon-s-responsibility
#3
Mohammed Bani Hani, Abdel Rahman Al Manasra, Haitham Qandeel
PURPOSE: Gallstones patients without preoperative history of jaundice, deranged liver function tests, or dilated bile ducts (BD) are unlikely to have BD stones. However, some of these patients in our series underwent endoscopic stone(s) removal after laparoscopic cholecystectomy (LC). We aim to find the incidence, possible intraoperative risk factors, and if the Surgeon can be blamed for this event. MATERIALS AND METHODS: We studied LC cases over 12-year period at our university hospital and identified patients who did not have preoperative risk factors for BD stones but developed postoperative jaundice and/or persistent abdominal pain...
February 16, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28212153/new-therapies-for-the-prevention-and-treatment-of-exacerbations-of-bronchiectasis
#4
Hani Abo-Leyah, James D Chalmers
PURPOSE OF REVIEW: Exacerbations of bronchiectasis have a major impact on quality of life, healthcare costs, and long-term risk of complications. Preventing exacerbations is one of the major goals of treatment. Bronchiectasis is increasingly recognized and the impact of bronchiectasis exacerbations on daily clinical practice is also increasing. RECENT FINDINGS: Preventing bronchiectasis exacerbations are dependent on appropriate risk assessment, identifying the patients at highest risk to rationally target preventive therapies...
February 16, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28211883/the-inflammatory-state-provokes-sexual-dimorphism-in-left-ventricular-and-electrocardiographic-effects-of-chronic-cyclosporine-in-rats
#5
Hany M El-Bassossy, Zainy M Banjar, Mahmoud M El-Mas
Although cardiotoxicity has been recognized as an adverse effect of cyclosporine A (CSA), no information exists regarding sex specificity of CSA cardiotoxicity. We tested the hypothesis that left ventricular (LV) and electrocardiographic (ECG) effects of CSA and related inflammatory/histopathological derangements are sex related. CSA reduced the LV slope of end-systolic pressure volume relationship and increased isovolumic relaxation constant. These effects were more pronounced in male compared to female rats, suggesting LV systolic and diastolic dysfunction...
February 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28210977/genetic-characterization-of-adenoid-cystic-carcinoma-of-the-minor-salivary-glands-a-potential-familial-occurrence-in-first-degree-relatives
#6
Hani Ibrahim Channir, Thomas van Overeem Hansen, Simon Andreasen, Christina Westmose Yde, Katalin Kiss, Birgitte Wittenborg Charabi
Adenoid cystic carcinoma (AdCC) is a malignant salivary gland tumor. To date, no cases of AdCC in first-degree relatives have been reported in the literature. We present a 50-year-old female (Case 1) and this patients' father (Case 2), both of whom were diagnosed with AdCC of the minor salivary glands. Histology of Case 1 demonstrated a tubulocribriform AdCC whereas Case 2 primarily was an AdCC of solid type. Both cases harbored the MYB-NFIB gene fusion as demonstrated by FISH and RNA-sequencing. After filtering and selection of putative deleterious variants, whole exome sequencing identified 18 germline variants in common between Case 1 and Case 2...
February 16, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28209748/the-use-of-hyperbaric-oxygen-for-the-prevention-and-management-of-osteoradionecrosis-of-the-jaw-a-dana-farber-brigham-and-women-s-cancer-center-multidisciplinary-guideline
#7
REVIEW
Ahmed Sultan, Glenn J Hanna, Danielle N Margalit, Nicole Chau, Laura A Goguen, Francisco M Marty, Guilherme Rabinowits, Jonathan D Schoenfeld, Stephen T Sonis, Tom Thomas, Roy B Tishler, Nathaniel S Treister, Alessandro Villa, Sook-Bin Woo, Robert Haddad, Hani Mawardi
BACKGROUND: Osteoradionecrosis of the jaw (ORN) is an infrequent yet potentially devastating complication of radiation therapy to the head and neck region. Treatment options include antimicrobial therapy, local sequestrectomy, resection, and the use of hyperbaric oxygen (HBO). Published data on ORN are difficult to compare because of the lack of a universally accepted classification and staging system, and the literature on the use of HBO to either prevent or successfully manage ORN is controversial and inconclusive...
February 16, 2017: Oncologist
https://www.readbyqxmd.com/read/28205426/a-study-of-hla-b-15-02-in-9-different-chinese-ethnics-implications-for-carbamazepine-related-sjs-ten
#8
G J Ou, J Wang, X Ji, H Yu, L Jiang, L Li, Q Chen, P C Su, Z Liu
BACKGROUND: HLA-B*15:02 is a known biomarker for carbamazepine (CBZ)-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) in some ethnic populations. The US FDA recommends B*15:02 screening for Asian and other populations with a high prevalence of B*15:02 prior to treatment with CBZ to prevent drug-related SJS/TEN. MATERIALS AND METHODS: A total of 1607 blood samples were collected from volunteer blood donors who were ethnic minorities living in the Yunnan province of southwestern China, including 153 Yi, 193 Naxi, 167 Miao, 156 Lisu, 166 Derung, 211 Bai, 184 Hani, 198 Dai, and 179 Zhuang...
February 15, 2017: HLA
https://www.readbyqxmd.com/read/28204997/predicting-surgical-outcome-in-patients-with-glioblastoma-multiforme-using-pre-operative-magnetic-resonance-imaging-development-and-preliminary-validation-of-a-grading-system
#9
Hani J Marcus, Sophie Williams, Archie Hughes-Hallett, Sophie J Camp, Dipankar Nandi, Lewis Thorne
The lack of a simple, objective and reproducible system to describe glioblastoma multiforme (GBM) represents a major limitation in comparative effectiveness research. The objectives of this study were therefore to develop such a grading system and to validate it on patients who underwent surgical resection. A systematic review of the literature was performed to identify features on pre-operative magnetic resonance imaging (MRI) that predict the surgical outcome of patients with GBM. In all, the five most important features of GBM on pre-operative MRI were as follows: periventricular or deep location, corpus callosum or bilateral location, eloquent location, size and associated oedema...
February 15, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28198924/the-issue-of-race-in-the-work-of-domingos-guedes-cabral
#10
Juanma Sánchez Arteaga, Ronnie Jorge Tavares de Almeida, Charbel Niño El-Hani
In 1875 Bahia, medicine and evolutionism were used by the physician, journalist, and republican militant Domingos Guedes Cabral as ideological weapons to propose a radical program of social reforms in Brazil in the areas of education, marriage control, medical care to the alienated, changes in the penal system, etc., all of which were based on the scientific knowledge of that time. Among the social ideas of Guedes Cabral, the question of race will be the main focus of this analysis. In this sense, Domingos Guedes Cabral is a particularly significant example for understanding the initial steps in the peculiar alliance between evolutionism, medicine, and scientific racism in Brazil since the 1870s, when Darwinism first arrived in the country...
December 2016: História, Ciências, Saúde—Manguinhos
https://www.readbyqxmd.com/read/28194321/extranodal-natural-killer-t-cell-lymphoma-presenting-as-orbital-cellulitis
#11
Hanis Zuhaimy, Hayati Abdul Aziz, Suresh Vasudevan, Siah Hui Hui
Objective: To report an aggressive case of extranodal natural killer/T-cell lymphoma (NKTCL) of the ethmoid sinus presenting as orbital cellulitis Method: Case report Results: A 56-year-old male presented with right eye redness, reduced vision, and periorbital swelling for 5 weeks duration associated with a two-month history of blocked nose. The visual acuity of the right eye was 6/18. The eye was proptosed with periorbital oedema and conjunctival chemosis. The pupil was mid-dilated but there was no relative afferent pupillary defect...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28191016/incidence-and-molecular-characterization-of-hepatitis-e-virus-from-swine-in-eastern-cape-south-africa
#12
Olusesan Adeyemi Adelabu, Benson Chuks Iweriebor, U U Nwodo, Larry Chikwelu Obi, Anthony Ifeanyi Okoh
Hepatitis E virus-mediated infection is a serious public health concern in economically developing nations of the world. Globally, four major genotypes of HEV have been documented. Hepatitis E has been suggested to be zoonotic owing to the increase of evidence through various studies. Thus far, this paper reports on prevalence of hepatitis E virus among swine herd in selected communal and commercial farms in the Eastern Cape Province of South Africa. A total of 160 faecal samples were collected from swine herds in Amathole and Chris Hani District Municipalities of Eastern Cape Province for the presence of HEV...
2017: Advances in Virology
https://www.readbyqxmd.com/read/28186449/efficacy-and-outcomes-of-facial-nerve-sparing-treatment-approach-to-cerebellopontine-angle-meningiomas
#13
Randy S D'Amico, Matei A Banu, Petros Petridis, Alexandra S Bercow, Hani Malone, Moshe Praver, Tony J C Wang, Steven R Isaacson, Michael B Sisti
OBJECTIVE Advanced microsurgical techniques contribute to reduced morbidity and improved surgical management of meningiomas arising within the cerebellopontine angle (CPA). However, the goal of surgery has evolved to preserve the quality of the patient's life, even if it means leaving residual tumor. Concurrently, Gamma Knife radiosurgery (GKRS) has become an acceptable and effective treatment modality for newly diagnosed, recurrent, or progressive meningiomas of the CPA. The authors review their institutional experience with CPA meningiomas treated with GKRS, surgery, or a combination of surgery and GKRS...
February 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28185703/bnp-and-obesity-in-acute-decompensated-heart-failure-with-preserved-vs-reduced-ejection-fraction-the-atherosclerosis-risk-in-communities-surveillance-study
#14
Umair Khalid, Lisa Miller Wruck, Pedro Miguel Quibrera, Biykem Bozkurt, Vijay Nambi, Salim S Virani, Hani Jneid, Sunil Agarwal, Patricia P Chang, Laura Loehr, Sukhdeep Singh Basra, Wayne Rosamond, Christie M Ballantyne, Anita Deswal
BACKGROUND: Levels of B-type natriuretic peptide (BNP), a prognostic marker in patients with heart failure (HF), are lower among HF patients with obesity or preserved Left Ventricular Ejection Fraction (LVEF). We examined the distribution and prognostic value of BNP across BMI categories in acute decompensated heart failure (ADHF) patients with preserved vs. reduced LVEF. METHODS: We analyzed data from the Atherosclerosis Risk in Communities (ARIC) HF surveillance study which sampled and adjudicated ADHF hospitalizations in patients aged ≥55years from 4 US communities (2005-2009)...
January 31, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28183804/reduced-mitochondrial-activity-in-colonocytes-facilitates-ampk%C3%AE-2-dependent-inflammation
#15
Sandra Heller, Harrison M Penrose, Chloe Cable, Debjani Biswas, Hani Nakhoul, Melody Baddoo, Erik Flemington, Susan E Crawford, Suzana D Savkovic
Intestinal inflammation is associated with low levels of mucosal ATP, highlighting the importance of mitochondrial function associated with ATP production in the pathophysiology of the disease. In the inflamed colon of humans and mice, we found decreased levels of mitochondrial complex cytochrome c oxidase I/IV and lower ATP levels. Thus, we generated colonic ρ(0) cells with reduced mitochondrial function linked to ATP production by selective depletion of mitochondrial DNA. In these cells, RNA sequencing revealed a substantial number of differentially expressed transcripts, among which 240 belonged to inflammatory pathways activated in human inflamed colon and TNF-α-treated cells (false discovery rate < 0...
February 9, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28183580/effect-of-total-intravenous-vs-volatile-anesthetics-on-intraoperatively-acquired-electrically-evoked-compound-action-potential-in-children-undergoing-cochlear-implant-surgery-a-randomized-prospective-study
#16
Ala A Alhowary, Khaled El-Radaideh, Anas Al-Rusan, Diab Bani Hani, Wail Khraise, Ahmad Al Omari, Firas Alzoubi
OBJECTIVE: The purpose of the present study was to compare the effects of inhalational anesthesia to those of total intravenous anesthesia on intraoperative electrically evoked compound action potential (e-ECAP) thresholds in children undergoing cochlear implantation. STUDY DESIGN: Randomized prospective study. SETTING: Tertiary referral teaching hospital. PATIENTS: Forty children aged 6 months to 17years with bilateral severe-to-profound sensorineural hearing loss and undergoing cochlear implantation were enrolled in the study...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28182410/luminescent-cyclometalated-platinum-complexes-with-%C3%AF-bonded-catecholate-organometallic-ligands
#17
Jamal Moussa, Aruny Loch, Lise-Marie Chamoreau, Alessandra Degli Esposti, Elisa Bandini, Andrea Barbieri, Hani Amouri
A series of cyclometalated platinum(II) complexes of the type [(ppy)Pt(LM)](n+) (n = 0, 1) with π-bonded catecholates acting as organometallic ligands (LM) have been prepared and characterized by analytical techniques. In addition, the structures of two complexes of the series were determined by single-crystal X-ray diffraction. The packing shows the formation of a 1D supramolecular assembly generated by dPt-πCp* interactions among individual units. All complexes are luminescent in the solid state and in solution media...
February 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28182191/mir-155-modifies-inflammation-endothelial-activation-and-blood-brain-barrier-dysfunction-in-cerebral-malaria
#18
Kevin Richard Barker, Ziyue Lu, Hani Kim, Ying Zheng, Junmei Chen, Andrea L Conroy, Michael Hawkes, Henry S Cheng, Makon-Sébastien Njock, Jason E Fish, John M Harlan, Jose A López, W Conrad Liles, Kevin C Kain
miR-155 has been shown to participate in host response to infection and neuro-inflammation via negative regulation of blood-brain-barrier (BBB) integrity and T cell function. We hypothesized that miR-155 may contribute to the pathogenesis of cerebral malaria (CM). To test this hypothesis, we used a genetic approach to modulate miR-155 expression in an experimental model of cerebral malaria (ECM). In addition, an engineered endothelialized microvessel system and serum samples from Ugandan children with CM were used to examine an anti-miR-155 as a potential adjunctive therapeutic for severe malaria...
February 2, 2017: Molecular Medicine
https://www.readbyqxmd.com/read/28179960/ternary-semitransparent-organic-solar-cells-with-a-laminated-top-electrode
#19
Mohammed Makha, Paolo Testa, Surendra Babu Anantharaman, Jakob Heier, Sandra Jenatsch, Nicolas Leclaire, Jean-Nicolas Tisserant, Anna C Véron, Lei Wang, Frank Nüesch, Roland Hany
Tinted and colour-neutral semitransparent organic photovoltaic elements are of interest for building-integrated applications in windows, on glass roofs or on facades. We demonstrate a semitransparent organic photovoltaic cell with a dry-laminated top electrode that achieves a uniform average visible transmittance of 51% and a power conversion efficiency of 3%. The photo-active material is based on a majority blend composed of a visibly absorbing donor polymer and a fullerene acceptor, to which a selective near-infrared absorbing cyanine dye is added as a minority component...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28179619/rituximab-can-induce-remission-in-a-patient-with-ankylosing-spondylitis-who-failed-anti-tnf-%C3%AE-agent
#20
Fahmi AlDhaheri, Talal Almteri, Naji Dwid, Ahd Majdali, Nahed Janoudi, Hani Almoallim
BACKGROUND Ankylosing spondylitis (AS) is a chronic inflammatory disease that predominantly affects the axial skeleton. The ability of anti-TNF-α agents to reduce disease activity in patients with axial spondyloarthritis (axSpA), including AS, has been demonstrated in multiple randomized trials and several meta-analyses. Reports on the efficacy of rituximab in treatment of AS have described good results. We report on a patient with AS who failed anti-TNF-α therapy but showed good clinical improvement with rituximab therapy...
February 9, 2017: American Journal of Case Reports
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