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aortic endocarditis

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https://www.readbyqxmd.com/read/28719311/infective-endocarditis-in-french-west-indies-a-13-year-observational-study
#1
Elisabeth Fernandes, Claude Olive, Jocelyn Inamo, François Roques, André Cabié, Patrick Hochedez
We conducted an observational study to describe the characteristics of infective endocarditis (IE) in French West Indies (FWI) and to identify variables associated with in-hospital case fatality. The records of the patients admitted for IE to the University Hospital of Martinique between 2000 and 2012 were collected using an electronic case report form. Only Duke-Li definite cases were considered for this analysis. Variables associated with in-hospital mortality were tested using univariate logistic regression analysis...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717038/a-human-biofilm-disrupting-monoclonal-antibody-potentiates-antibiotic-efficacy-in-rodent-models-of-both-staphylococcus-aureus-and-acinetobacter-baumannii-infections
#2
Yan Q Xiong, Angeles Estellés, L Li, W Abdelhady, R Gonzales, Arnold S Bayer, Edgar Tenorio, Anton Leighton, Stefan Ryser, Lawrence M Kauvar
Many serious bacterial infections are antibiotic-refractory due to biofilm formation. A key structural component of biofilm is extracellular DNA which is stabilized by bacterial proteins, including those from the DNABII family. TRL1068 is a high affinity human monoclonal antibody against a DNABII epitope conserved across both gram-positive and gram-negative bacterial species. In the current study, the efficacy of TRL1068 for disruption of biofilm was demonstrated in vitro in the absence of antibiotics by scanning electron microscopy...
July 17, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28713024/to-retrieve-or-not-to-retrieve-system-revisions-with-the-micra-transcatheter-pacemaker
#3
Eric Grubman, Philippe Ritter, Christopher R Ellis, Michael Giocondo, Ralph Augostini, Petr Neuzil, Bipin Ravindran, Anshul M Patel, Pamela Omdahl, Karen Pieper, Kurt Stromberg, J Harrison Hudnall, Dwight Reynolds
BACKGROUND: Early experience with leadless pacemakers has shown a low rate of complications. However, little is known about system revision in patients with these devices. OBJECTIVE: To describe the system revision experience with the Micra Transcatheter Pacing System (TPS). METHODS: Implanted patients from the Micra TPS and the Micra Continued Access study (N = 989) were analyzed and compared to 2667 patients with transvenous pacemakers (TVP)...
July 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28711529/initial-treatment-strategy-for-intracranial-mycotic-aneurysms-two-case-reports-and-literature-review
#4
Makoto Ohtake, Kensuke Tateishi, Naoki Ikegaya, Junya Iwata, Shoji Yamanaka, Hidetoshi Murata
BACKGROUND: Intracranial mycotic aneurysm (IMA) is a rare neurovascular disease and a well-known complication following infective endocarditis. IMAs potentially carry a high mortality risk due to intracranial hemorrhage. Therefore, initial treatment is crucial for IMA patients, but an optimal treatment strategy remains unknown. Herein, we report two cases of IMA patients treated with the current usual modalities, and we provide a comprehensive literature review to propose an optimal initial treatment strategy for IMAs...
July 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28707745/survival-of-the-fetus-during-maternal-thoracotomy-under-cardiopulmonary-bypass-for-infective-endocarditis
#5
Li Luo, Qiulei Sun, Liping Chen, Demei Ying, Xiaohua Wu, Zhengqiong Chen
Infective endocarditis (IE) during pregnancy is a rare but serious condition. Cardiopulmonary bypass during pregnancy has a high rate of fetal morbidity and mortality. We here report the case of a 22-year-old pregnant woman with confirmed IE. Multiple large cardiac valve vegetations, severe aortic valve regurgitation, and hemodynamic compromise were observed. With full implementation of fetal monitoring and protection strategies, open heart surgery was performed at 31.4 weeks' gestation to aid survival, followed by an elective cesarean delivery at 34...
July 14, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28704282/excessive-surgical-adhesive-mimicking-aortic-root-abscess-a-case-report
#6
Natalie A Silverton, David A Bull, Candice K Morrissey
Aortic root abscess is a complication of aortic valve endocarditis that is associated with a high morbidity and mortality. The diagnosis usually is made with transesophageal echocardiography, which is highly sensitive and specific for the disease. We present a case of suspected aortic root abscess 1 week after mechanical aortic valve replacement for native valve endocarditis. The diagnosis was made by the use of transesophageal echocardiography but surgical inspection revealed that the paravalvular fluid collection was excessive surgical adhesive...
July 15, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28698908/-adult-autopsies-during-the-past-decade-in-germany-data-from-two-university-hospitals
#7
F Erlmeier, W Weichert, R Knüchel, J Andruszkow
BACKGROUND: The clinical autopsy is the ultimate medical service for a patient and plays a crucial role in the education of physicians and other medical personnel, as well as in the context of quality control. Nevertheless, the number of autopsies is constantly decreasing. Numerous factors, such as the personal attitude of relatives and also clarification of relatives, as well as the increasing application of imaging methods while the patient is still alive, play a central role in this decline...
July 11, 2017: Der Pathologe
https://www.readbyqxmd.com/read/28689527/dual-infection-by-burkholderia-cepaciaand-pseudomonas-putida-in-an-infective-endocarditis-case
#8
Maria Khan, Farida Khurram Lalani, Aamer Ikram, Gohar Zaman, Parvez Ahmed
Infective endocarditis is rarely caused by Burkholderia cepacia. Pseudomonas putidahas not been reported to cause infective endocarditis so far. This is the first case of infective endocarditis being reported, that is caused by Pseudomonas putidaand Burkholderia cepaciain an immunocompetent host with no predisposing factors. Aortic valve replacement surgery was carried out and antibiotics were given, to which the patient responded well and recovered.
June 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28688312/total-proximal-anastomosis-detachment-after-classical-bentall-procedure
#9
Aref Rashed, Karoly Gombocz, Andras Vigh, Nasri Alotti
INTRODUCTION: Since its introduction in 1968, the Bentall procedure has been the primary surgical solution for aneurysms of the aortic root. However, many surgeons have reported serious procedural complications such as detachment of coronary ostia and pseudoaneurysm formation at anastomosis sites. Therefore, the Bentall procedure has undergone several modifications to eliminate those complications. Partial or total detachment of the proximal anastomosis is rarely reported. PRESENTATION OF CASE: We report a total detachment of the proximal anastomosis after a Bentall operation with emphasis on the possible practical mechanisms, which might have led to the development of this very rare complication...
June 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28683983/sutureless-sorin-perceval-aortic-valve-implantation
#10
Steffen Pfeiffer, Theodor Fischlein, Giuseppe Santarpino
The sutureless Perceval aortic valve (Sorin Group, Saluggia, Italy) is a device increasingly used in many European cardiac surgery centers. Since the first reports evaluating implantation feasibility and valve safety in humans in 2007, an increasing amount of data have become available, including premarketing clinical results and experience in particular conditions. Overall, excellent performances have been demonstrated in hemodynamic outcomes, safety, and versatility of use. However, several questions remain unanswered, especially regarding long-term durability, risk for endocarditis, and the need for postoperative pacemaker implantation...
April 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28683904/surgery-for-diseases-of-the-aortic-root
#11
REVIEW
Robbin G Cohen, Ramsey S Elsayed, Michael E Bowdish
The aortic root is the junction between the heart and aorta, containing the aortic valve and the coronary artery ostia. Various pathologic conditions arise in this region requiring complex surgical correction. These include aneurysmal dilatation with and without aortic regurgitation, acute aortic dissection extending below the sinotubular junction, and infective endocarditis with valve and periannular destruction. Multiple strategies for correction of these complex surgical issues exist, with excellent early results and long-term survival...
August 2017: Cardiology Clinics
https://www.readbyqxmd.com/read/28680649/aorto-right-ventricular-fistula-a-rare-complication-of-abiotrophia-endocarditis
#12
Priyanka Bhattacharya, Aasim Mohammed, Eddy Mizrahi
A 41-year-old African male presented with worsening dyspnea and cachexia concerning for congestive heart failure. Transesophageal echocardiogram revealed a large mass attached to the aortic valve leaflet, mass attached to the flail anterior mitral valve leaflet, severe pulmonary hypertension and dilatation of the aortic root along with fistula between the right coronary aortic cusp and the right ventricular (RV) outflow tract. Blood cultures grew Abiotrophia Defectiva (AD) sensitive to vancomycin. Patient underwent emergent surgical closure of aorto RV fistula and aortic root replacement along with pulmonary and mitral valve replacement...
July 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28674620/risk-and-outcomes-of-aortic-valve-endocarditis-among-patients-with-bicuspid-and-tricuspid-aortic-valves
#13
Yuka Kiyota, Alessandro Della Corte, Vanessa Montiero Vieira, Karam Habchi, Chuan-Chin Huang, Ester E Della Ratta, Thoralf M Sundt, Prem Shekar, Jochen D Muehlschlegel, Simon C Body
OBJECTIVE: Patients with structural abnormalities of cardiac valves, including bicuspid aortic valve (BAV), are said to be at higher risk of infective endocarditis (IE). We sought to determine the risk of IE of the BAV compared with the tricuspid aortic valve (TAV) and to determine the risk of aortic valve replacement and mortality after IE. METHODS: From medical records of two US and one Italian hospitals, patients with their first episode of IE of any native valve were identified...
2017: Open Heart
https://www.readbyqxmd.com/read/28671806/valvular-heart-disease-in-adults-management-of-prosthetic-heart-valves
#14
John F Trujillo, Steven M Hollenberg
Patients undergoing cardiac valve replacement may receive mechanical or bioprosthetic valves. Mechanical valves require lifelong anticoagulation but are durable and the need for a second surgery is up to eightfold times less than with bioprosthetic valves. Bioprosthetic valves do not require lifelong anticoagulation and thus are associated with fewer bleeding complications but they are less durable and associated with higher morbidity and mortality rates, particularly in younger patients. Anticoagulation with mechanical valves is achieved using warfarin; use of direct-acting oral anticoagulants is not indicated...
June 2017: FP Essentials
https://www.readbyqxmd.com/read/28671804/valvular-heart-disease-in-adults-etiologies-classification-and-diagnosis
#15
Steven M Hollenberg
The prevalence of valvular heart disease (VHD) in the United States was estimated to be approximately 2.5% in the 1990s. The prevalence currently is thought to be increasing because of more accurate diagnostic methods and aging of the population. Mitral regurgitation (MR) is the most common valve defect, followed by aortic stenosis (AS) and aortic regurgitation (AR). Degenerative disease is the most common etiology of MR, AS, and AR, though these forms of VHD also can be caused by congenital valve defects, systemic inflammatory diseases, endocarditis, and many other conditions...
June 2017: FP Essentials
https://www.readbyqxmd.com/read/28670063/aorto-right-atrial-fistula-after-bentall-repair
#16
Charles E Howard, Carlos E Velasco, Christina P Roullard, Aldo Rafael
We describe a man with the Marfan syndrome and a prior ascending aortic aneurysm resection who presented with knee pain and concern of endocarditis. Transesophageal echocardiogram showed no vegetations, and computed tomography angiogram of the heart showed a possible pseudoaneurysm. Cardiac catheterization and aortogram revealed the diagnosis of an aorto-right atrial fistula, which was then operatively repaired. This case highlights the role that cardiac catheterization with aortogram can play in the detection of aorto-atrial fistula...
July 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28669832/hyperbaric-oxygen-treatment-augments-tobramycin-efficacy-in-experimental-staphylococcus-aureus-endocarditis
#17
C J Lerche, L J Christophersen, M Kolpen, P R Nielsen, H Trøstrup, K Thomsen, O Hyldegaard, H Bundgaard, P Ø Jensen, N Høiby, C Moser
BACKGROUND: S. aureus infective endocarditis (IE) is a serious disease an in-hospital mortality of up to 40%. Improvements of effects of antibiotics and host responses could potentially benefit outcomes. Hyperbaric oxygen treatment (HBOT) represents an adjunctive therapeutic option. We evaluated the efficacy of HBOT in combination with tobramycin in S. aureus IE. METHODS: A rat model of S. aureus IE mimicking the bacterial load in humans was used. Infected rats treated with tobramycin were randomized into two groups, 1) HBOT (b...
June 29, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28669501/surgical-ablation-of-atrial-fibrillation-in-the-united-states-trends-and-propensity-matched-outcomes
#18
Vinay Badhwar, J Scott Rankin, Niv Ad, Maria Grau-Sepulveda, Ralph J Damiano, A Marc Gillinov, Patrick M McCarthy, Vinod H Thourani, Rakesh M Suri, Jeffrey P Jacobs, James L Cox
BACKGROUND: Surgical ablation (SA) for atrial fibrillation (AF) effectively restores sinus rhythm. Incompletely defined risk has previously limited concomitant performance of SA during cardiac operations. The study goals were to define performance trends and risk-adjusted outcomes for contemporary SA. METHODS: From July 2011 to June 2014, 86,941 patients with AF, but without endocarditis, underwent primary nonemergent cardiac operations in The Society of Thoracic Surgeons (STS) database...
June 29, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28666146/intraleaflet-hemorrhages-are-a-common-finding-in-symptomatic-aortic-and-mitral-valves
#19
Olga C G Stam, Mat J A P Daemen, Jan Willem van Rijswijk, Bas A J M de Mol, Allard C van der Wal
INTRODUCTION: Intraleaflet hemorrhage (ILH) has been reported to occur in calcified degenerated aortic valves. At present, no such information is available for mitral valves or for other types of valvular disease. We examined the prevalence, age, and potential source of ILH in a consecutive series of surgically removed aortic and mitral valves, and related the findings to specific types of heart valve pathology. METHODS: A total of 105 aortic (n=85) and mitral (n=20) valves were retrieved from 100 symptomatic patients...
June 17, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28657456/challenging-diagnosis-of-prosthetic-infective-endocarditis-and-para-aortic-conduit-abscess-the-role-of-multimodality-approach
#20
Virginija Rudiene, Sigita Glaveckaite, Diana Zakarkaite, Rimantas Karalius, Lina Gumbiene
No abstract text is available yet for this article.
June 28, 2017: Acta Cardiologica
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