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aortic endocarditis

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https://www.readbyqxmd.com/read/29673380/a-standardized-approach-to-treat-complex-aortic-valve-endocarditis-a-case-series
#1
Anna Gomes, Jayant S Jainandunsing, Sander van Assen, Peter Paul van Geel, Bhanu Sinha, Sandro Gelsomino, Daniel M Johnson, Ehsan Natour
BACKGROUND: Surgical treatment of complicated aortic valve endocarditis often is challenging, even for experienced surgeons. We aim at demonstrating a standardized surgical approach by stentless bioprostheses for the treatment of aortic valve endocarditis complicated by paravalvular abscess formation. METHODS: Sixteen patients presenting with aortic valve endocarditis (4 native and 12 prosthetic valves) and paravalvular abscess formation at various localizations and to different extents were treated by a standardized approach using stentless bioprostheses...
April 19, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29670602/human-genetic-susceptibility-to-native-valve-staphylococcus-aureus-endocarditis-in-patients-with-s-aureus-bacteremia-genome-wide-association-study
#2
Karen Moreau, Alisson Clemenceau, Vincent Le Moing, David Messika-Zeitoun, Paal S Andersen, Niels E Bruun, Robert L Skov, Florence Couzon, Coralie Bouchiat, Marie L Erpelding, Alex van Belkum, Yohan Bossé, Xavier Duval, Francois Vandenesch
Staphylococcus aureus infective endocarditis (SaIE) is a severe complication of S. aureus bacteremia (SAB) occurring in up to 22% of patients. Bacterial genetic factors and host conditions for SaIE have been intensely studied before; however, to date no study has focused on predisposing host genetic factors to SaIE. The present study aimed to identify genetic polymorphisms associated with SaIE by a Genome-Wide Association Study (GWAS) of 67 patients with definite native valve SaIE (cases) and 72 matched native valve patients with SAB but without IE (controls)...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29657952/surgical-treatment-of-annuloaortic-ectasia-replace-or-repair
#3
Andrea De Martino, Federico Del Re, Stefania Blasi, Michele Celiento, Giacomo Ravenni, Stefano Pratali, Aldo D Milano, Uberto Bortolotti
Background: Patients with annuloaortic ectasia may be surgically treated with modified Bentall or David I valve-sparing procedures. Here, we compared the long-term results of these procedures. Methods: A total of 181 patients with annuloaortic ectasia underwent modified Bentall (102 patients, Group 1) or David I (79 patients, Group 2) procedures from 1994 to 2015. Mean age was 62 ± 11 years in Group 1 and 64 ± 16 years in Group 2. Group 1 patients were in poorer health, with a lower ejection fraction and higher functional class...
October 2017: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/29656818/the-aortic-root-does-not-dilate-over-time-after-replacement-of-the-aortic-valve-and-ascending-aorta-in-patients-with-bicuspid-or-tricuspid-aortic-valves
#4
Sonya K Hui, Chun-Po Steve Fan, Shakira Christie, Christopher M Feindel, Tirone E David, Maral Ouzounian
OBJECTIVE: Whether the aortopathy associated with bicuspid aortic valve (BAV) disease occurs secondary to genetic or hemodynamic factors remains controversial. In this article we describe the natural history of the aortic root in patients with bicuspid versus tricuspid aortic valves (TAVs) after replacement of the aortic valve and ascending aorta. METHODS: From 1990 to 2010, 406 patients (269 BAV, 137 TAV) underwent aortic valve and ascending aorta replacement at a single institution...
March 13, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29643124/myocardial-ischemia-as-a-result-of-external-coronary-compression-from-infective-aortic-root-aneurysm-atypical-presentation-of-prosthetic-valve-endocarditis
#5
Baskar Sekar, Richard Wheeler, Navroz Masani, Sean Gallagher
This case describes an unusual presentation of prosthetic valve endocarditis: an acute coronary syndrome. A 67-year-old gentleman presented with cardiac sounding chest pain on a background of a short history of night sweats, weight loss and general malaise. Four months previously he had undergone bio-prosthetic aortic valve replacement for severe aortic stenosis and single vessel bypass grafting of the obtuse marginal. Whilst having chest pain his ECG showed infero-lateral ST depression. Early coronary angiography revealed a new right coronary artery lesion that was not present prior to his cardiac surgery...
April 11, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29625103/aortic-valve-reoperation-following-stentless-bioprosthesis-short-and-long-term-outcomes
#6
Bo Yang, Himanshu J Patel, Elizabeth L Norton, Christina Debenedictus, Linda Farhat, Xiaoting Wu, Kevin He, Whitney E Hornsby, Donald S Likosky, G Michael Deeb
BACKGROUND: Limited data are available regarding outcomes for stentless aortic valve reoperation. The reported reoperative mortality has been unacceptably high. METHODS: Between 1997-2017, a retrospective analysis was performed on 143 patients that underwent open aortic valve reoperations for failed stentless aortic valve bioprostheses. We evaluated both short- and long-term outcomes on this cohort of patients. RESULTS: Bicuspid aortic valve was present in 107/143 (75%) of patients at the time of the initial Freestyle procedure and 84% (120/143) patients underwent a modified inclusion aortic root replacement procedure...
April 3, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29623558/why-i-choose-to-repair-and-not-to-replace-the-aortic-valve
#7
Athanasios Antoniou, Amer Harky, Mohamad Bashir, Gebrine El Khoury
Aortic valve replacement whether surgical or transcutaneous remains an option for the treatment of severe aortic valve disease; however, current prosthetic devices are associated with complications including, but no limited to, valve thrombosis and thromboembolic events, bleeding events associated with anticoagulation use, prosthetic valve endocarditis and structural valve deterioration. In this effect, aortic valve repair (AVr) has become an attractive alternative in circumventing these potential complications by preservation of the native aortic valve apparatus...
April 5, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29619328/ciprofloxacin-for-the-treatment-of-cardiobacterium-hominis-prosthetic-valve-endocarditis
#8
Lisa M Avery, Catherine B Felberbaum, Muhammad Hasan
Prosthetic valve endocarditis due to Cardiobacterium hominis is rare and recommended therapy includes a third generation cephalosporin. We report a case of Cardiobacterium hominis endocarditis post transcatheter aortic valve replacement in a patient with significant beta-lactam antimicrobial sensitivities who was successfully treated with ciprofloxacin monotherapy in conjunction with surgery.
2018: IDCases
https://www.readbyqxmd.com/read/29617499/mortality-predictors-in-the-surgical-treatment-of-active-infective-endocarditis
#9
Jenny Lourdes Rivas de Oliveira, Magaly Arrais Dos Santos, Renato Tambellini Arnoni, Auristela Ramos, Dorival Della Togna, Samira Kaissar Ghorayeb, Roberto Tadeu Magro Kroll, Luiz Carlos Bento de Souza
INTRODUCTION: Active infective endocarditis is associated with high morbidity and mortality. Surgery is indicated in high-risk conditions, and the main determinants of mortality in surgical treatment should be evaluated. OBJECTIVE: To identify mortality predictors in the surgical treatment of active infective endocarditis in a long-term follow-up. METHODS: This prospective observational study involved 88 consecutive patients diagnosed with active infective endocarditis, who underwent surgery between January 2005 and December 2015...
January 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29614534/-current-concepts-of-cardiologic-therapies-in-the-elderly
#10
Ursula Müller-Werdan, Kristina Norman
MYOCARDIAL INFARCTION IN THE OLD PATIENT: Even old patients may crucially benefit from reopening the occluded coronary artery by percutaneous coronary intervention with stent implantation. Bleeding complications can be reduced by choosing the radial instead of the femoral vascular approach for cardiac catheterization. STATINS FOR THE ELDERLY: WHEN TO START UND WHEN TO STOP?: Elderly benefit no less than the younger from statins. "Goal-oriented statin therapy" is preferable to the "statin strategy of fixed dose"...
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29610194/the-combination-of-daptomycin-plus-fosfomycin-has-synergistic-potent-and-rapid-bactericidal-activity-against-methicillin-resistant-staphylococcus-aureus-mrsa-in-a-rabbit-model-of-experimental-endocarditis-ee
#11
Cristina García-de-la-Mària, Oriol Gasch, Javier García-Gonzalez, Dolors Soy, Evelyn Shaw, Juan Ambrosioni, Manel Almela, Juan M Pericàs, Adrián Tellez, Carlos Falces, Marta Hernandez-Meneses, Elena Sandoval, Eduard Quintana, Barbara Vidal, Jose M Tolosana, David Fuster, Jaume Llopis, Miquel Pujol, Asuncion Moreno, Francesc Marco, Jose M Miró
This study aims to investigate whether the addition of fosfomycin or cloxacillin to daptomycin provides better outcomes in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) experimental aortic endocarditis in rabbits. Five MRSA strains were used to perform in vitro time-kill studies at standard (105) and high (108) inocula. Combined therapy was compared with daptomycin monotherapy treatment in the MRSA experimental endocarditis model. A human-like pharmacokinetics model was applied and the equivalents of cloxacillin 2g/4hiv, fosfomycin 2g/6h iv and daptomycin 6-10mg/kg/d iv were administered...
April 2, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29609891/bentall-procedure-after-previous-aortic-valve-or-complete-root-replacement-usefulness-of-self-assembled-aortic-valve-conduit
#12
Paul P Urbanski, Fitsum Lakew, Witold Dinstak, Nicolas Heinz, Michael Zacher, Vadim Irimie, Wilko Reents
OBJECTIVES: The aim of this study was to evaluate surgical results of complete aortic root replacement using self-assembled valve composite graft in the setting of destroyed aortic annulus after previous valve replacement. METHODS: Aortic root pathology being addressed by complete root replacement was combined with partial or complete absence of annular tissue in 112 consecutive patients. Eighty-eight had undergone a previous replacement of the aortic valve and 24 had undergone root replacement with a valved conduit...
March 11, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29607162/early-and-mid-term-haemodynamic-performance-and-clinical-outcomes-of-st-jude-medical-trifecta%C3%A2-valve
#13
Renata Raimundo, Soraia Moreira, Francisca Saraiva, Rui J Cerqueira, Pedro Teixeira, Elson Salgueiro, André Lourenço, Mário J Amorim, Jorge Almeida, Paulo Pinho, Adelino F Leite-Moreira
Background: New models of aortic bioprostheses have proven excellent early haemodynamic profile, but their mid and long-term performance warrants further systematic assessment. The aim of this study is to report clinical and haemodynamic performance of St. Jude Medical Trifecta bioprosthesis during 5 years of implantation. Methods: We performed a single centre, retrospective, observational and descriptive study including all 556 individuals who underwent aortic valve replacement (AVR) with the Trifecta bioprosthesis (between July of 2011 and June of 2016)...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29593919/double-native-valve-infective-endocarditis-due-to-capnocytophaga-canimorsus-first-reported-case-caused-by-a-lion-bite
#14
Mazin Barry
Capnocytophaga canimorsus is a Gram-negative bacilli that is part of the normal oral flora of dogs and some cats; it is well known to cause septicemia and endocarditis after their bite. This is the first reported case of infective endocarditis affecting both native mitral and aortic valves after a lion bite in a patient with heavy ethanol consumption, who ultimately died after valve replacements.
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29584858/incidence-and-factors-associated-with-infective-endocarditis-in-patients-undergoing-left-sided-heart-valve-replacement
#15
Lauge Østergaard, Nana Valeur, Nikolaj Ihlemann, Morten Holdgaard Smerup, Henning Bundgaard, Gunnar Gislason, Christian Torp-Pedersen, Niels Eske Bruun, Lars Køber, Emil Loldrup Fosbøl
Aims: Patients with left-sided heart valve replacement are considered at high-risk of infective endocarditis (IE). However, data on the incidence and risk factors associated with IE are sparse. Methods and results: Through Danish administrative registries, we identified patients who underwent left-sided heart valve replacement from January 1996 to December 2015. Patients were categorized in mitral and aortic valve replacement (MVR and AVR) and followed until: 12 years after valve surgery, end of study, death, emigration, or hospitalization due to IE, whichever came first...
March 23, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29579243/aortic-cross-clamp-time-and-cardiopulmonary-bypass-time-prognostic-implications-in-patients-operated-on-for-infective-endocarditis
#16
Antonio Salsano, Daniele Roberto Giacobbe, Elena Sportelli, Guido Maria Olivieri, Roberto Natali, Martina Prevosto, Valerio Del Bono, Claudio Viscoli, Francesco Santini
OBJECTIVES: Prolonged aortic cross-clamp (XCT) and cardiopulmonary bypass time (CPBT) are associated with increased morbidity and mortality following cardiac surgery. The aim of this study was to assess the predictors of mortality and other severe postoperative complications in patients undergoing surgery for infective endocarditis (IE), focusing in particular on the role of prolonged XCT and CPBT. METHODS: A retrospective single-centre study was conducted from January 2000 to January 2017, including all patients undergoing valvular surgery for IE...
March 22, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29578396/antinephritis-associated-plasmin-receptor-naplr-antibody-positive-glomerulonephritis-caused-by-aggregatibacter-actinomycetemcomitans-bacteremia-a-case-report
#17
Yohei Komaru, Kunihiro Ishioka, Takashi Oda, Takayasu Ohtake, Shuzo Kobayashi
Infection-related glomerulonephritis (IRGN) develops after various infections. It was previously thought to be caused by Streptococcus species alone but can also be caused by other pathogens. Nephritis-associated plasmin receptor (NAPlr) was discovered as a candidate nephritis-inducing factor in acute post-streptococcal glomerulonephritis. More recently, renal lesions caused by other pathogens were found to be positive for the same molecular marker. We report the case of a 64-year-old man who experienced repeated fever for several months and presented with progressively-deteriorating renal function...
March 26, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29577926/type-a-aortic-dissection-following-the-ross-procedure
#18
Samuel Richey, Andrew C Fiore, Charles B Huddleston
We describe a case of Type A aortic dissection in a 25 year old lady who had undergone a Ross Procedure for aortic valve endocarditis 13 years previously. She was pregnant and noted to have significant enlargement of the aortic root during the latter portion of the third trimester of her pregnancy. An echocardiogram performed after delivery demonstrated new aortic valve insufficiency in addition to an aortic root diameter of 6.5 cm. A CT angiogram demonstrated a Type A aortic dissection involving only the very proximal portion of the ascending aorta...
March 22, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29569281/ruptured-mitral-valve-aneurysm-a-devastating-complication-of-aortic-valve-endocarditis
#19
Shokoufeh Hajsadeghi, Mehrab Marzban, Pegah Joghataie, Aida Iranpour
Mitral valve aneurysm is a rare clinical entity that is mostly resulted from infective endocarditis, in particular, aortic valve endocarditis. Once mitral valve aneurysm ruptures and severe mitral regurgitation and hemodynamic instability develop, prompt surgery should be considered. Here we report a patient with ruptured mitral valve aneurysm associated with native aortic valve endocarditis that was improved after a successful mitral and aortic valve replacement surgery associated with antibiotic therapy for 6 weeks...
March 22, 2018: Echocardiography
https://www.readbyqxmd.com/read/29567131/midterm-outcomes-after-aortic-valve-neocuspidization-with-glutaraldehyde-treated-autologous-pericardium
#20
Shigeyuki Ozaki, Isamu Kawase, Hiromasa Yamashita, Shin Uchida, Mikio Takatoh, Nagaki Kiyohara
OBJECTIVE: We had previously reported the short-term results of the aortic valve neocuspidization (AVNeo) procedure. We have now evaluated the midterm results with the longest follow-up of 118 months. METHODS: From April 2007 through December 2015, 850 patients were treated with AVNeo using autologous pericardium. Medical records of these patients were retrospectively reviewed. The procedure was on the basis of independent tricuspid replacement using autologous pericardium...
February 15, 2018: Journal of Thoracic and Cardiovascular Surgery
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