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Depression diagnosis

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https://www.readbyqxmd.com/read/29352386/glucose-homeostasis-in-major-depression-and-schizophrenia-a-comparison-among-drug-na%C3%A3-ve-first-episode-patients
#1
Johann Steiner, Brisa S Fernandes, Paul C Guest, Henrik Dobrowolny, Gabriela Meyer-Lotz, Sabine Westphal, Katrin Borucki, Kolja Schiltz, Zoltán Sarnyai, Hans-Gert Bernstein
There is evidence for insulin resistance in drug-naïve first-episode schizophrenia (Sz) patients. We have tested whether impaired insulin homeostasis is also present in first-episode patients with major depression (MD) and if this can be discerned from stress-related and medication effects. Homeostatic model assessment of insulin resistance (HOMA-IR) was determined in a cross-sectional cohort study of acute first-episode drug-naïve patients with MD (n = 18) or Sz (n = 24), and healthy controls (C, n = 43)...
January 19, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29351761/selective-serotonin-reuptake-inhibitor-use-and-breast-cancer-survival-a-population-based-cohort-study
#2
John Busby, Ken Mills, Shu-Dong Zhang, Fabio Giuseppe Liberante, Chris R Cardwell
BACKGROUND: Nearly 50% of breast cancer patients suffer from depression or anxiety. Selective serotonin reuptake inhibitors (SSRIs), the first-line pharmacological treatment for depression, have been implicated in breast cancer development through increased prolactin levels and tamoxifen metabolism inhibition. Previous studies of breast cancer progression have focused on tamoxifen users, or have been limited by their small sample size and methodology. Therefore, we used UK population-based data to more robustly investigate the association between SSRI use and cancer-specific mortality...
January 19, 2018: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/29351709/-validation-of-the-screening-for-complex-ptsd-skptbs-revision
#3
Florence Dorr, Martin Sack, Jürgen Bengel
BACKGROUND: The aim was to develop further a screening instrument for complex posttraumatic stress disorder (cPTSD). The screening for cPTSD (SkPTBS) tests a) potential traumatic experiences, b) influential features and risk factors, and c) symptoms of cPTSD. The SkPTBS by Dorr et al. (2016) was revised according to the current ICD-11 criteria set proposal for cPTSD and is explored in its revised edition. METHOD: Impacts of long-lasting interpersonal trauma were tested in inpatients of psychosomatic rehabilitation and in patients consulting a university outpatient center for trauma therapy...
January 19, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29350128/between-a-rock-a-bye-and-a-hard-place-mood-disorders-during-the-peripartum-period
#4
Michael Thomson, Verinder Sharma
Mood disorders including major depressive disorder and bipolar disorder are common during and after pregnancy. Timely identification and appropriate management of mood episodes is essential to maximize maternal well-being and minimize adverse outcomes. Failure to do so results in maternal suffering and impaired child bonding, and has the potential for devastating outcomes including suicide and infanticide. Women are routinely screened for unipolar depression during or after pregnancy but not for bipolar disorder, in spite of the fact that childbirth is associated with a major risk for onset or exacerbation of bipolar disorder...
December 2017: CNS Spectrums
https://www.readbyqxmd.com/read/29349251/undiagnosed-depression-a-community-diagnosis
#5
Sharifa Z Williams, Grace S Chung, Peter A Muennig
Many large provider networks are investing heavily in preventing disease within the communities that they serve. We explore the potential benefits and challenges associated with tackling depression at the community level using a unique dataset designed for one such provider network. The economic costs of having depression (increased medical care use, lower quality of life, and decreased workplace productivity) are among the highest of any disease. Depression often goes undiagnosed, yet many believe that depression can be treated or prevented altogether...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/29345878/impact-of-cognitive-impairment-on-functioning-in-patients-with-depression
#6
Raymond W Lam
Reassessing a patient's diagnosis if he or she does not respond adequately to initial antidepressant pharmacotherapy is imperative. In this CME activity, evaluate the case of Melissa, a 32-year-old architect with a potential case of treatment-resistant depression, and decide on appropriate treatment strategies.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345602/the-mental-health-of-adolescents-and-pre-adolescents-living-with-inherited-arrhythmia-syndromes-a-systematic-review-of-the-literature
#7
Patricia E Longmuir, Margaret Sampson, Jennifer Ham, Makenzie Weekes, Bhavika J Patel, Robert M Gow
Potentially fatal arrhythmias add to the mental health challenges of adolescence. This systematic review sought to summarise current knowledge regarding the mental health of adolescents and pre-adolescents diagnosed with inherited arrhythmia syndromes. Searches combining psychological problems with inherited cardiac arrhythmia diagnoses identified 16 studies with paediatric (<18 years) inherited arrhythmia patients. All studies were cross-sectional; 8/16 required an implantable cardioverter defibrillator...
January 18, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29344434/rare-multidrug-resistant-pulmonary-nocardiosis-in-aids
#8
Cherry O Onaiwu, Manasa Velagapudi, Luay Sarsam, Lindsay Utley, Lauren Bricker, Venkata Sunil Bendi, Renuga Vivekanandan
Nocardiosis is an opportunistic infection in patients with depressed cell-mediated immunity. Inhalation is the primary route for exposure via dust particles. Patients with acquired immune deficiency syndrome (AIDS) are at increased risk of disseminated disease. A challenge in the diagnosis of pulmonary nocardiosis is that it can mimic other pulmonary diseases. Nocardia farcinica tends to be a more virulent, multidrug-resistant strain with an increased tendency to disseminate. This report describes a 64-year-old man with AIDS found to have pulmonary nocardiosis that did not respond to standard antibiotic therapy...
November 11, 2017: Curēus
https://www.readbyqxmd.com/read/29343947/patient-preferences-for-important-attributes-of-bipolar-depression-treatments-a-discrete-choice-experiment
#9
Daisy Ng-Mak, Jiat-Ling Poon, Laurie Roberts, Leah Kleinman, Dennis A Revicki, Krithika Rajagopalan
Purpose: The purpose of this study was to assess patient preferences regarding pharmacological treatment attributes for bipolar depression using a discrete choice experiment (DCE). Methods: Adult members of an Internet survey panel with a self-reported diagnosis of bipolar depression were invited via e-mail to participate in a web-based DCE survey. Participants were asked to choose between hypothetical medication alternatives defined by attributes and levels that were varied systematically...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29343935/effectiveness-of-mindfulness-based-cognitive-therapy-in-patients-with-bipolar-affective-disorder-a-case-series
#10
Suvarna Shirish Joshi, Mahendra Prakash Sharma, Shivarama Varambally
The present investigation was undertaken to examine the effects of mindfulness-based cognitive therapy (MBCT) on interepisodic symptoms, emotional regulation, and quality of life in patients with bipolar affective disorder (BPAD) in remission. The sample for the study comprised a total of five patients with the diagnosis of BPAD in partial or complete remission. Each patient was screened to fit the inclusion and exclusion criteria and later assessed on the Beck Depressive Inventory I, Beck Anxiety Inventory, Difficulties in Emotion Regulation Scale, Acceptance and Action Questionnaire-II, and The World Health Organization Quality of Life Assessment-BREF...
January 2018: International Journal of Yoga
https://www.readbyqxmd.com/read/29343875/-trazodone-prolonged-release-in-bipolar-disorder-ii-obsessive-compulsive-disorder-comorbidity-a-case-report
#11
Liliana Lorettu, Giampiero Meli, Elena Antonioli, Antonio Zeppa, Paolo Milia, Alessandra Nivoli
Approximately 21% of patients with bipolar disorder (BD) also have an additional diagnosis of obsessive-compulsive disorder (OCD). This condition is associated with a more severe prognosis and complicates the treatment of BD. In our case report we provide documentary evidence of our experience with trazodone prolonged release in the treatment of depressive phase in a patient with BD II-OCD comorbidity. Rationality in the choise of treatment was based on the need to manage depressive and obsessive symptoms without facilitating hypomania switches...
November 2017: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29343237/subtypes-in-clinical-burnout-patients-enrolled-in-an-employee-rehabilitation-program-differences-in-burnout-profiles-depression-and-recovery-resources-stress-balance
#12
Kathrin Bauernhofer, Daniela Bassa, Markus Canazei, Paulino Jiménez, Manuela Paechter, Ilona Papousek, Andreas Fink, Elisabeth M Weiss
BACKGROUND: Burnout is generally perceived a unified disorder with homogeneous symptomatology across people (exhaustion, cynicism, and reduced professional efficacy). However, increasing evidence points to intra-individual patterns of burnout symptoms in non-clinical samples such as students, athletes, healthy, and burned-out employees. Different burnout subtypes might therefore exist. Yet, burnout subtypes based on burnout profiles have hardly been explored in clinical patients, and the samples investigated in previous studies were rather heterogeneous including patients with various physical, psychological, and social limitations, symptoms, and disabilities...
January 17, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29341270/pre-transplant-depression-in-lung-recipients-a-lost-battle
#13
Ivan Knezevic, Bojan Zalar
What have we learned so far about the relationship of the recipient's pre-transplant depression and his survival after lung transplantation? First, every chronic disease is always accompanied by somatic changes, functional limitations and emotional, cognitive and social changes as part of the disease. From the first symptoms, to the time of diagnosis of the chronic disease with the expected future, the patient is exposed to the terrible stress of denying and accepting life with a serious chronic illness whose end result is death...
January 16, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29341070/personality-changes-during-the-transition-from-cognitive-health-to-mild-cognitive-impairment
#14
Richard J Caselli, Blake T Langlais, Amylou C Dueck, Bruce R Henslin, Travis A Johnson, Bryan K Woodruff, Charlene Hoffman-Snyder, Dona E C Locke
BACKGROUND/OBJECTIVES: Behavioral problems in individuals with Alzheimer's disease (AD) impose major management challenges. Current prevention strategies are anchored to cognitive outcomes, but behavioral outcomes may provide another, clinically relevant opportunity for preemptive therapy. We sought to determine whether personality changes that predispose to behavioral disorders arise during the transition from preclinical AD to mild cognitive impairment (MCI). DESIGN: Longitudinal observational cohort study...
January 17, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29340941/internal-medicine-residents-attitudes-toward-simulated-depressed-cardiac-patients-during-an-objective-structured-clinical-examination-a-randomized-study
#15
Kathleen Crapanzano, Dixie Fisher, Rebecca Hammarlund, Eric P Hsieh, Win May
BACKGROUND: Physician biases toward mental conditions such as depression have been shown to adversely affect medical outcomes. OBJECTIVE: To explore the relationship between residents' explicit bias toward depressed patients and their clinical skills on a cardiac case during an objective structured clinical exam (OSCE). DESIGN: Prospective parallel randomized controlled study. PARTICIPANTS: One hundred eighty-five internal medicine residents from three residency programs in two states...
January 16, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29340877/brief-report-subjective-social-mobility-and-depressive-symptoms-in-syrian-refugees-to-germany
#16
Frank Euteneuer, Sarina J Schäfer
Previous findings indicate that refugees are at increased risk for mental health problems. In addition to stressful pre-migration experiences, post-migration factors may contribute to poor mental health outcomes. Among immigrants to the United States, downward mobility in subjective social status (SSS) was associated with depression, corroborating the potentially detrimental mental health consequences of a decline in one's perceived social position. The present study examined whether downward mobility in SSS among male refugees from Syria to Germany is associated with depression...
January 16, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29340244/an-exploratory-study-of-adolescent-response-to-fluoxetine-using-psychological-and-biological-predictors
#17
Ada H Zohar, Tamar Eilat, Maya Amitai, Michal Taler, Romi Bari, Alon Chen, Alan Apter, Avraham Weizman, Silvana Fennig
Background: Not enough is known about predicting therapeutic response to serotonin-specific reuptake inhibitors, and specifically to fluoxetine. This exploratory study used psychological and biological markers for (retrospective) prediction of treatment-response to fluoxetine in depressed and/or anxious adolescents. Methods: Forty-one consecutive adolescent outpatients with a primary diagnosis of severe affective and/or anxiety disorders were assessed and treated with an open-label 8-week trial of fluoxetine...
2018: PeerJ
https://www.readbyqxmd.com/read/29339309/late-chronotype-is-associated-with-enhanced-amygdala-reactivity-and-reduced-fronto-limbic-functional-connectivity-to-fearful-versus-happy-facial-expressions
#18
Charlotte Mary Horne, Ray Norbury
Increasing evidence suggests late chronotype individuals are at increased risk of developing depression. However, the underlying neural mechanisms that confer risk are not fully understood. Here, fifty healthy, right-handed individuals without a current or previous diagnosis of depression, family history of depression or sleep disorder underwent functional magnetic resonance imaging (FMRI). Participants completed an implicit emotion processing task (gender discrimination) including happy and fearful facial expressions...
January 12, 2018: NeuroImage
https://www.readbyqxmd.com/read/29339257/changes-in-the-concentrations-of-inflammatory-and-oxidative-status-biomediators-mip-1-%C3%AE-pmn-elastase-mda-and-il-12-in-depressed-patients-with-and-without-posttraumatic-stress-disorder
#19
Ewa A Ogłodek
BACKGROUND: Both proinflammatory cytokines and oxidative stress are considered an imbalance between the cellular production of reactive oxygen species and the antioxidant defense mechanisms. An inflammatory response that occurs in depression leads to a synergy between pro-inflammatory cytokines and oxidative stress. This synergy induces common signal transduction pathways that boost the inflammatory cascade. The object of this study was to assess the concentrations of inflammatory and oxidative status biomediators such as MIP-1α, PMN elastase, MDA, and IL-12 in depressed patients with and without posttraumatic stress disorder (PTSD), and with PTSD alone...
August 26, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29339128/anxiety-and-depression-effects-during-drug-provocation-test
#20
Laura Michelina Losappio, Alessandra Cappai, Alessandra Arcolaci, Iuliana Badiu, Patrizia Bonadonna, Elisa Boni, Claudia Bussolino, Marco Caminati, Pietro Galati, Enrico Heffler, Rossella Intravaia, Marina Mauro, Ilaria Massaro, Antonino Romano, Gabriele Rumi, Anna Parolo, Stefano Pizzimenti, Michele Nichelatti, Elide Anna Pastorello
BACKGROUND: Drug provocation test (DPT) represents the gold standard for the diagnosis of drug allergy. A DPT can be performed in a single-blind placebo-controlled manner. In anxiety and depressive disorders, patients need to be evaluated to understand the nature of placebo reactions. OBJECTIVE: The aim of this study was to evaluate the psychological profile of patients with reactions to placebo during a DPT. METHODS: We consecutively enrolled patients with suspected drug allergy undergoing a DPT preceded by the administration of the placebo...
January 12, 2018: Journal of Allergy and Clinical Immunology in Practice
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