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https://www.readbyqxmd.com/read/28934668/diabetes-mellitus-increased-all-cause-mortality-rate-among-newly-diagnosed-tuberculosis-patients-in-an-asian-population-a-nationwide-population-based-study
#1
Po-Yen Ko, Shi-Dou Lin, Ming-Chia Hsieh, Yu-Cheng Chen
AIMS: To investigate the effect of diabetes mellitus (DM) on all-cause mortality among patients with newly-diagnosed tuberculosis (TB) in an Asian population. We also identified risk factors for mortality in these patients. METHODS: The data were obtained from the National Health Insurance Research Database and included 9831 newly-diagnosed TB individuals and 1627 TB mortality cases in the period of 2000-2010. The mortality data were divided into a DM group and a non-DM group...
September 1, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28934604/prognostic-value-of-lipoprotein-associated-phospholipase-a2-mass-for-all-cause-mortality-and-vascular-events-within-one-year-after-acute-ischemic-stroke
#2
Liyuan Han, Chongke Zhong, Xiaoqing Bu, Tan Xu, Aili Wang, Yanbo Peng, Tian Xu, Jinchao Wang, Hao Peng, Qunwei Li, Zhong Ju, Deqing Geng, Yonghong Zhang, Jiang He
BACKGROUND AND AIMS: We performed a prospective investigation of the longer-term prognostic value of lipoprotein-associated phospholipase A2 (Lp-PLA2) mass for all-cause mortality and vascular events within one year after acute ischemic stroke. METHODS: We examined the Lp-PLA2 mass among 3401 participants enrolled in the China Antihypertensive Trial in Acute Ischemic Stroke. The primary outcome was all-cause mortality. Cox proportional hazard ratios (HRs) and 95% confidence intervals (95% CIs) were constructed to assess the independent associations between the baseline Lp-PLA2 mass and the outcomes after adjustment for variables in models 1, 2, and 3 [further adjusted for low-density lipoprotein cholesterol (LDL-C)]...
September 14, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28934412/gorenek-b-et-al-device-detected-subclinical-atrial-tachyarrhythmias-definition-implications-and-management-an-european-heart-rhythm-association-ehra-consensus-document-endorsed-by-heart-rhythm-society-hrs-asia-pacific-heart-rhythm-society-aphrs-and-sociedad
#3
https://www.readbyqxmd.com/read/28934408/device-detected-subclinical-atrial-tachyarrhythmias-definition-implications-and-management-an-european-heart-rhythm-association-ehra-consensus-document-endorsed-by-heart-rhythm-society-hrs-asia-pacific-heart-rhythm-society-aphrs-and-sociedad-latinoamericana
#4
Bulent Gorenek, Jeroen Bax, Giuseppe Boriani, Shih-Ann Chen, Nikolaos Dagres, Taya V Glotzer, Jeff S Healey, Carsten W Israel, Gulmira Kudaiberdieva, Lars-Åke Levin, Gregory Y H Lip, David Martin, Ken Okumura, Jesper H Svendsen, Hung-Fat Tse, Giovanni L Botto, Cecilia Linde, Valentina Kutyifa, Robert Bernat, Daniel Scherr, Chu-Pak Lau, Pedro Iturralde, Daniel P Morin, Irina Savelieva
No abstract text is available yet for this article.
September 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28934319/an-examination-of-objectively-measured-sedentary-behavior-and-mental-well-being-in-adults-across-week-days-and-weekends
#5
Ann-Marie Gibson, David J Muggeridge, Adrienne R Hughes, Louise Kelly, Alison Kirk
BACKGROUND: Limited research has explored the links between sedentary behaviour, mental health and quality of life. This study examines objectively measured sedentary behaviour and perceived mental health and quality of life across week days and weekends. METHODS: 42 adults (19M, 23F; mean age 38yrs (range 18-67) & BMI 24.8kg/m2 (range 18.7-33.8) wore an activPAL monitor 24h/day for one week and completed the Hospital Anxiety and Depression Scale (HADS) and SF12 Health Survey...
2017: PloS One
https://www.readbyqxmd.com/read/28934092/insecticide-use-and-breast-cancer-risk-among-farmers-wives-in-the-agricultural-health-study
#6
Lawrence S Engel, Emily Werder, Jaya Satagopan, Aaron Blair, Jane A Hoppin, Stella Koutros, Catherine C Lerro, Dale P Sandler, Michael C Alavanja, Laura E Beane Freeman
BACKGROUND: Some epidemiologic and laboratory studies suggest that insecticides are related to increased breast cancer risk, but the evidence is inconsistent. Women engaged in agricultural work or who reside in agricultural areas may experience appreciable exposures to a wide range of insecticides. OBJECTIVE: We examined associations between insecticide use and breast cancer incidence among wives of pesticide applicators (farmers) in the prospective Agricultural Health Study...
September 6, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28933053/incidence-and-all-cause-mortality-for-hip-fracture-in-comparison-to-stroke-and-myocardial-infarction-a-fifteen-years-population-based-longitudinal-study
#7
Vincenzo Carnevale, Andrea Fontana, Alfredo Scillitani, Roberto Sinisi, Elisabetta Romagnoli, Massimiliano Copetti
PURPOSE: This population-based study investigated the incidence, in-hospital and long-term all-cause mortality, for hip fracture (HipFx), stroke (STR), and myocardial infarction (MI) in residents hospitalized between 2000 and 2014. METHODS: Data about hospitalization were drawn from the administrative discharge database, whereas information about residents and all-cause mortality from the municipality of our town. Patients were followed-up from the first hospital admission until death or study end...
September 20, 2017: Endocrine
https://www.readbyqxmd.com/read/28931910/the-role-of-charge-balance-and-excited-state-levels-on-device-performance-of-exciplex-based-phosphorescent-organic-light-emitting-diodes
#8
Sangyeob Lee, Hyun Koo, Ohyun Kwon, Young Jae Park, Hyeonho Choi, Kwan Lee, Byungmin Ahn, Young Min Park
The design of novel exciplex-forming co-host materials provides new opportunities to achieve high device performance of organic light emitting diodes (OLEDs), including high efficiency, low driving voltage and low efficiency roll-off. Here, we report a comprehensive study of exciplex-forming co-host system in OLEDs including the change of co-host materials, mixing composition of exciplex in the device to improve the performance. We investigate various exciplex systems using 5-(3-4,6-diphenyl-1,3,5-triazin-2-yl)phenyl-3,9-diphenyl-9H-carbazole, 5-(3-4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-9-phenyl-9H-3,9'-bicarbazole, and 2-(3-(6,9-diphenyl-9H-carbazol-4-yl)phenyl)-4-phenylbenzo[4,5]thieno[3,2-d]pyrimidine, as electron transporting (ET: electron acceptor) hosts and 9,9'-dipenyl-9H, 9'H-3,3'-bicarbazole and 9-([1,1'-biphenyl]-4-yl)-9'-phenyl-9H,9'H-3,3'-bicarbazole as hole transporting (HT: electron donor) hosts...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931849/dipstick-proteinuria-and-risk-of-myocardial-infarction-and-all-cause-mortality-in-diabetes-or-pre-diabetes-a-population-based-cohort-study
#9
Jinwei Wang, Junjuan Li, Anxin Wang, Jianli Wang, Yaozheng Yang, Shuohua Chen, Shouling Wu, Minghui Zhao, Xiuhua Guo, Luxia Zhang
To evaluate the association between dipstick proteinuria and myocardial infarction (MI) or all-cause mortality, a cohort study was conducted among 16,573 general Chinese population with diabetes or pre-diabetes, which were defined as self-reported history of diabetes or fasting blood glucose ≥5.6 mmol/L or under blood glucose lowering therapy. Proteinuria was detected biennially during 2006-2013 by dipstick test. MI and all-cause mortality were recorded through the end of 2014. Mean age (standard deviation) of study participants was 51...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931533/inflammatory-potential-of-the-diet-and-colorectal-tumor-risk-in-persons-with-lynch-syndrome
#10
Jesca Gm Brouwer, Maureen Makama, Geertruida J van Woudenbergh, Hans Fa Vasen, Fokko M Nagengast, Jan H Kleibeuker, Ellen Kampman, Fränzel Jb van Duijnhoven
Background: Persons with Lynch syndrome (LS) have high lifetime risk of developing colorectal tumors (CRTs) because of a germline mutation in one of their mismatch repair (MMR) genes. An important process in the development of CRTs is inflammation, which has been shown to be modulated by diet.Objective: We aimed to investigate the association between the inflammatory potential of the diet and the risk of CRTs in persons with LS.Design: We used the dietary intake of 457 persons with LS from a prospective cohort study to calculate the adapted dietary inflammatory index (ADII)...
September 20, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28930859/p16-methylation-was-associated-with-the-development-age-hepatic-viruses-infection-of-hepatocellular-carcinoma-and-p16-expression-had-a-poor-survival-a-systematic-meta-analysis-prisma
#11
Xueyou Lv, Guoliang Ye, Xinjun Zhang, Tao Huang
BACKGROUND: Loss of tumor suppressor gene p16 expression via promoter methylation has been reported in hepatocellular carcinoma (HCC). This meta-analysis was conducted to evaluate the correlation between p16 methylation and HCC. Additionally, we also analyzed the potential prognostic role of p16 methylation, expression or alteration-associated HCC. METHODS: Online databases based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guideline were performed to analyze the role of p16 gene in HCC...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930829/the-curative-effects-of-radiotherapy-based-therapies-for-human-epidermal-growth-factor-receptor-2-positive-breast-cancer-a-meta-analysis
#12
Minghai Shao, Chi Zhang, Qin Qin, Zhaoyue Zhang, Hongcheng Zhu, Xiaoke Di, Xinchen Sun
AIM: This meta-analysis was designed to fully assess the curative effects of radiotherapy-based therapies for human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC). METHODS: English articles were retrieved through searching Cochrane library, PubMed, and Embase databases updated to February 2017. Studies were selected based on the inclusion and exclusion criteria. The curative effects of radiotherapy-based therapies forHER2+ BC patients were assessed using hazard rates (HRs) or odds ratios (ORs), as well as their 95% confidence intervals (CIs)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930374/the-prognostic-significance-of-soluble-programmed-death-ligand-1-expression-in-cancers-a-systematic-review-and-meta-analysis
#13
REVIEW
Y Ding, C Sun, J Li, L Hu, M Li, J Liu, L Pu, S Xiong
The differential expression of soluble programmed death ligand 1 (sPD-L1) has been found in some cancers; however, the correlation between sPD-L1 expression and prognosis value in tumour is still unclear. Here, we conducted a meta-analysis and systematic review to assess the prognostic value of sPD-L1 in patients with cancer. Eligible studies were searched for in the databases including PubMed, Web of Science, ScienceDirect and Wiley Online Library database. The pooled hazard ratios (HRs) with a 95% confidence interval (95%CI) were calculated to assess the prognostic significance of sPD-L1 in human cancer...
August 21, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28929584/association-between-oral-leukoplakia-and-risk-of-upper-gastrointestinal-cancer-death-a-follow-up-study-of-the-linxian-general-population-trial
#14
He Liang, Zhao Yang, Jian-Bing Wang, Pei Yu, Jin-Hu Fan, You-Lin Qiao, Philip R Taylor
BACKGROUND: This study was conducted to explore the association between oral leukoplakia (OL) and the risk of upper gastrointestinal cancer death in the Linxian General Population Trial Cohort. METHODS: A prospective cohort study of the Linxian General Population Trial Cohort was performed. Participants with OL were treated as an exposed group, and the remainder was selected as a control group. All subjects were followed monthly by village health workers and reviewed quarterly by the Linxian Cancer Registry...
September 20, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28928223/psychological-distress-and-ischaemic-heart-disease-cause-or-consequence-evidence-from-a-large-prospective-cohort-study
#15
Jennifer Welsh, Rosemary J Korda, Grace Joshy, Peter Butterworth, Alex Brown, Emily Banks
BACKGROUND: Ischaemic heart disease (IHD) incidence is elevated in people reporting psychological distress. The extent to which this relationship is causal or related to reverse causality-that is, undiagnosed disease causing distress-is unclear. We quantified the relationship between psychological distress and IHD, with consideration of confounding and undiagnosed disease. METHODS: Questionnaire data (2006-2009) from 151 811 cardiovascular disease-free and cancer-free Australian general population members aged ≥45years (45 and Up Study) were linked to hospitalisation and mortality data, to December 2013...
September 19, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28928197/impact-of-oral-self-care-on-incident-functional-disability-in-elderly-japanese-the-ohsaki-cohort-2006-study
#16
Shino Bando, Yasutake Tomata, Jun Aida, Kemmyo Sugiyama, Yumi Sugawara, Ichiro Tsuji
OBJECTIVES: To assess whether oral self-care (tooth brushing, regular dental visits and use of dentures) affects incident functional disability in elderly individuals with tooth loss. DESIGN: A 5.7-year prospective cohort study. SETTING: Ohsaki City, Japan. PARTICIPANTS: 12 370 community-dwelling individuals aged 65 years and older. PRIMARY OUTCOME MEASURES: Incident functional disability (new long-term care insurance certification)...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28928182/gender-differences-in-longevity-in-free-living-older-adults-who-eat-with-others-a-prospective-study-in-taiwan
#17
Yi-Chen Huang, Hsing-Ling Cheng, Mark L Wahlqvist, Yuan-Ting C Lo, Meei-Shyuan Lee
OBJECTIVES: Social activities such as 'eating-with-others' can positively affect the ageing process. We investigated the gender-specific association between eating arrangements and risk of all-cause mortality among free-living older adults. SETTING: A representative sample from the Elderly Nutrition and Health Survey in Taiwan during 1999-2000. PARTICIPANTS: Some 1894 participants (955 men and 939 women) who aged ≥65 and completed eating arrangement question as well as confirmed survivorship information...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28928176/controlling-nutritional-status-conut-score-as-a-predictor-of-all-cause-mortality-in-elderly-hypertensive-patients-a-prospective-follow-up-study
#18
Xiaonan Sun, Leiming Luo, Xiaoqian Zhao, Ping Ye
OBJECTIVES: The aim of this study was to elucidate the impact of nutritional status on survival per Controlling Nutritional Status (CONUT) score and Geriatric Nutritional Risk Index (GNRI) in patients with hypertension over 80 years of age. DESIGN: Prospective follow-up study. PARTICIPANTS: A total of 336 hypertensive patients over 80 years old were included in this study. OUTCOME MEASURES: All-cause deaths were recorded as Kaplan-Meier curves to evaluate the association between CONUT and all-cause mortality at follow-up...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28928046/new-directions-for-ambulatory-monitoring-following-2017-hrs-ishne-expert-consensus
#19
Emanuela T Locati
The main role of ambulatory electrocardiography (AECG) in clinical practice is to detect and characterize the behavior of cardiac electrical activity during ordinary daily life activities. Because certain rhythm abnormalities may be infrequent and paroxysmal, and may occur only during sleep or in association with mental, emotional, or exercise-induced perturbation in cardiac function, AECG needs to be recorded over a long period of time, originally lasting 24h and now expanding up to several weeks and even to months...
August 12, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28927706/cardiovascular-safety-and-efficacy-of-the-pcsk9-inhibitor-evolocumab-in-patients-with-and-without-diabetes-and-the-effect-of-evolocumab-on-glycaemia-and-risk-of-new-onset-diabetes-a-prespecified-analysis-of-the-fourier-randomised-controlled-trial
#20
Marc S Sabatine, Lawrence A Leiter, Stephen D Wiviott, Robert P Giugliano, Prakash Deedwania, Gaetano M De Ferrari, Sabina A Murphy, Julia F Kuder, Ioanna Gouni-Berthold, Basil S Lewis, Yehuda Handelsman, Armando Lira Pineda, Narimon Honarpour, Anthony C Keech, Peter S Sever, Terje R Pedersen
BACKGROUND: The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor evolocumab reduced LDL cholesterol and cardiovascular events in the FOURIER trial. In this prespecified analysis of FOURIER, we investigated the efficacy and safety of evolocumab by diabetes status and the effect of evolocumab on glycaemia and risk of developing diabetes. METHODS: FOURIER was a randomised trial of evolocumab (140 mg every 2 weeks or 420 mg once per month) versus placebo in 27 564 patients with atherosclerotic disease who were on statin therapy, followed up for a median of 2·2 years...
September 14, 2017: Lancet Diabetes & Endocrinology
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