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https://www.readbyqxmd.com/read/28923165/cross-sectional-study-of-area-level-disadvantage-and-glycaemic-related-risk-in-community-health-service-users-in-the-southern-iml-research-simlr-cohort
#1
Roger Cross, Andrew Bonney, Darren J Mayne, Kathryn M Weston
Objectives The aim of the present study was to determine the association between area-level socioeconomic disadvantage and glycaemic-related risk in health service users in the Illawarra-Shoalhaven region of New South Wales, Australia.Methods HbA1c values recorded between 2010 and 2012 for non-pregnant individuals aged ≥18 years were extracted from the Southern.IML Research (SIMLR) database. Individuals were assigned quintiles of the Socioeconomic Indices for Australia (SEIFA) Index of Relative Socioeconomic Disadvantage (IRSD) according to their Statistical Area 1 of residence...
September 19, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28922006/process-factors-explaining-psycho-social-outcomes-in-adventure-therapy
#2
Keith C Russell, Harold L Lee Gillis, Dennis M Kivlighan
The development and factor analysis of the Adventure Therapy Experience Scale (ATES) is the first attempt found in the literature to empirically and quantitatively identify therapeutic factors theorized to affect change in the adventure therapy experience (Russell & Gillis, 2017). This study utilizes the ATES to explore how its inherent factors may impact treatment outcome utilizing a routine outcome monitoring process to empirically test how these factors may contribute to treatment outcome over time. The sample of 168 males 21...
September 2017: Psychotherapy
https://www.readbyqxmd.com/read/28921646/how-often-are-drugs-made-available-under-the-food-and-drug-administration-s-expanded-access-process-approved
#3
Amy E McKee, André O Markon, Kirk M Chan-Tack, Peter Lurie
In this review of individual patient expanded-access requests to the Center for Drug Evaluation and Research for the period Fiscal Year 2010 to Fiscal Year 2014, we evaluated the number of applications received and the number allowed to proceed. We also evaluated whether drugs and certain biologics obtained under expanded access went on to be approved by the Food and Drug Administration. Finally, we considered concerns that adverse events occurring during expanded access might place sponsors at risk for legal liability...
October 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28917364/managing-childhood-and-adolescent-attention-deficit-hyperactivity-disorder-adhd-with-exercise-a-systematic-review
#4
REVIEW
Qin Xiang Ng, Collin Yih Xian Ho, Hwei Wuen Chan, Bob Zheng Jie Yong, Wee-Song Yeo
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders affecting some 8-10% of children worldwide. Increasing research has shed light on the life course of the disorder, suggesting that majority of children with ADHD will continue to have persistent symptoms into adulthood. The mainstay of ADHD management has been pharmacologic and behavioural/psychological interventions, with little attention paid to exercise as a potential management strategy...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28916877/bile-duct-injury-and-morbidity-following-cholecystectomy-a-need-for-improvement
#5
Meredith Barrett, Horacio J Asbun, Hung-Lung Chien, L Michael Brunt, Dana A Telem
BACKGROUND: Bile duct injury (BDI) remains the most dreaded complication following cholecystectomy with serious repercussions for the surgeon, patient and entire healthcare system. In the absence of registries, the true incidence of BDI in the United States remains unknown. We aim to identify the incidence of BDI requiring operative intervention and overall complications after cholecystectomy. METHODS: Utilizing the Truven Marketscan(®) research database, 554,806 patients who underwent cholecystectomy in calendar years 2011-2014 were identified using ICD-9 procedure and diagnosis codes...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28910123/consumer-factors-predicting-level-of-treatment-response-to-illness-management-and-recovery
#6
Dominique A White, Alan B McGuire, Lauren Luther, Adrienne I Anderson, Peter Phalen, John H McGrew
OBJECTIVE: This study aims to identify consumer-level predictors of level of treatment response to illness management and recovery (IMR) to target the appropriate consumers and aid psychiatric rehabilitation settings in developing intervention adaptations. METHOD: Secondary analyses from a multisite study of IMR were conducted. Self-report data from consumer participants of the parent study (n = 236) were analyzed for the current study. Consumers completed prepost surveys assessing illness management, coping, goal-related hope, social support, medication adherence, and working alliance...
September 14, 2017: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/28905438/research-to-support-optimization-of-prescription-drug-monitoring-programs
#7
Sheri Doyle, Gillian Leichtling, Christi Hildebran, Cynthia Reilly
PURPOSE: Research is needed to evaluate the impact of prescription drug monitoring programs (PDMPs). This paper describes research priorities for PDMPs that were initially discussed at a 2015 meeting of PDMP administrators, researchers, public health officials, and other stakeholders. METHODS: Meeting participants defined the current landscape of PDMP research and identified research gaps. Research priorities were grouped by theme. RESULTS: Prescription drug monitoring program research priorities were identified for 3 key areas: individual patient health outcomes, prescriber use and decision making, and population-level outcomes...
September 14, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28905305/a-systematic-review-of-promising-strategies-of-faith-based-cancer-education-and-lifestyle-interventions-among-racial-ethnic-minority-groups
#8
REVIEW
Su-I Hou, Xian Cao
Church-based interventions have been used to reach racial/ethnic minorities. In order to develop effective programs, we conducted a comprehensive systematic review of faith-based cancer prevention studies (2005~2016) to examine characteristics and promising strategies. Combination terms "church or faith-based or religion," "intervention or program," and "cancer education or lifestyle" were used in searching the five major databases: CINAHL; ERIC; Health Technology Assessments; MEDLINE; and PsycInfo. A total of 20 studies met study criteria...
September 13, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28904183/the-tb-portals-an-open-access-web-based-platform-for-global-drug-resistant-tuberculosis-data-sharing-and-analysis
#9
Alex Rosenthal, Andrei Gabrielian, Eric Engle, Darrell E Hurt, Sofia Alexandru, Valeriu Crudu, Eugene Sergueev, Valery Kirichenko, Vladzimir Lapitskii, Eduard Snezhko, Vassili Kovalev, Andrei Astrovko, Alena Skrahina, Jessica Taaffe, Michael Harris, Alyssa Long, Kurt Wollenberg, Irada Akhundova, Sharafat Ismayilova, Aliaksandr Skrahin, Elcan Mammadbayov, Hagigat Gadirova, Rafik Abuzarov, Mehriban Seyfaddinova, Zaza Avaliani, Irina Strambu, Dragos Zaharia, Alexandru Muntean, Eugenia Ghita, Miron Bogdan, Roxana Mindru, Victor Spinu, Alexandra Sora, Catalina Ene, Sergo Vashakidze, Natalia Shubladze, Ucha Nanava, Alexander Tuzikov, Michael Tartakovsky
The TB Portals Program is an international consortium of physicians, radiologists, and microbiologists from countries with a heavy burden of drug-resistant tuberculosis working with data scientists and IT professionals. Together, we have built the TB Portals, a repository of socioeconomic/geographic, clinical, laboratory, radiological, and genomic data from patient cases of drug-resistant tuberculosis and backed by shareable, physical samples. Currently, there are 1,299 total cases from five country sites (Azerbaijan, Belarus, Moldova, Georgia, and Romania), of which 976 (75...
September 13, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28902395/finding-homologs-in-amino-acid-sequences-using-network-blast-searches
#10
Istvan Ladunga
BLAST, the Basic Local Alignment Search Tool, is used more frequently than any other biosequence database search program. We show how to run searches on the Web, and demonstrate how to increase performance by fine-tuning arguments for a specific research project. We offer guidance for interpreting results, statistical significance and biological relevance issues, and suggest complementary analyses. This unit covers both protein-to-protein (blastp) searches and translated searches (blastx, tblastn, tfastx). blastx conceptually translates the query sequence and tblastn translates all nucleotide sequences in a database, while tblastx translates both the query and the database sequences into amino acid sequences...
September 13, 2017: Current Protocols in Bioinformatics
https://www.readbyqxmd.com/read/28901228/the-world-database-for-pediatric-and-congenital-heart-surgery-the-dawn-of-a-new-era-of-global-communication-and-quality-improvement-in-congenital-heart-disease
#11
James D St Louis, Hiromi Kurosawa, Richard A Jonas, Nestor Sandoval, Jorge Cervantes, Christo I Tchervenkov, Jeffery P Jacobs, Kisaburo Sakamoto, Giovanni Stellin, James K Kirklin
The World Society for Pediatric and Congenital Heart Surgery was founded with the mission to "promote the highest quality comprehensive cardiac care to all patients with congenital heart disease, from the fetus to the adult, regardless of the patient's economic means, with an emphasis on excellence in teaching, research, and community service." Early on, the Society's members realized that a crucial step in meeting this goal was to establish a global database that would collect vital information, allowing cardiac surgical centers worldwide to benchmark their outcomes and improve the quality of congenital heart disease care...
September 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28899388/a-review-of-grey-and-academic-literature-of-evaluation-guidance-relevant-to-public-health-interventions
#12
Sarah Denford, Charles Abraham, Margaret Callaghan, Peter Aighton, Frank De Vocht, Steven Arris
BACKGROUND: Public Health evaluation is essential to understanding what does and does not work, and robust demonstration of effectiveness may be crucial to securing future funding. Despite this, programs are often implemented with poor, incomplete or no evaluation. Public health practitioners are frequently required to provide evidence for the effectiveness of their services; thus, there is a growing need for evaluation guidance on how to evaluate public health programs. The aim of this study is to identify accessible high-quality, evaluation guidance, available to researchers and practitioners and to catalogue, summarise and categorise the content of a subset of accessible, quality guides to evaluation...
September 12, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28898767/what-do-we-know-about-student-resilience-in-health-professional-education-a-scoping-review-of-the-literature
#13
REVIEW
Brooke Sanderson, Margo Brewer
OBJECTIVES: Resilience has been identified as a key capability to thrive in the complex changing work environment of the 21st century. Therefore, the aim of this scoping review was to investigate how resilience is understood in the context of pre-qualifying health education, if there is a need to build student resilience, and what approaches to enhancing student resilience are described in the literature. DESIGN AND DATA SOURCES: Arksey and O'Malley's (2005) literature scoping review design was adopted as it enables researchers to review, summarise and analyse the literature on a given topic...
August 16, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28894698/paradigm-shift-toward-reducing-overtreatment-of-ductal-carcinoma-in-situ-of-breast
#14
REVIEW
Yasuaki Sagara, Wong Julia, Mehra Golshan, Masakazu Toi
The prevalence of ductal carcinoma in situ (DCIS) of the breast has increased substantially after the introduction of breast cancer screening programs, although the clinical effects of early DCIS detection and treatment remain unclear. The standard treatment for DCIS has involved local breast-conserving surgery (BCS) followed by radiotherapy (RT) or total mastectomy with/without endocrine therapy, and the choice of local treatment is not usually based on clinicopathologic or biological factors. However, we have investigated the effectiveness of local treatment using breast surgery and RT using Surveillance, Epidemiology, and End Results data, and found that the effectiveness of breast surgery was modified by the nuclear grade...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28894537/lifestyles-in-suburban-populations-a-systematic-review
#15
REVIEW
Samira Khayat, Mahrokh Dolatian, Ali Navidian, Zohreh Mahmoodi, Nasibeh Sharifi, Amir Kasaeian
BACKGROUND: Lifestyle and suburban population are important issues in the field of health. The living conditions of informal settlements can lead to acquisition of an unhealthy lifestyle. OBJECTIVE: This study has been designed to investigate the articles that have been published regarding lifestyle in suburban populations. METHODS: The present research was a systematic review of studies in databases including Iranmedex, Magiran, SID, Irandoc, PubMed, Google Scholar, Science Direct and Scopus, in 2017...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28893639/on-the-application-of-reverse-vaccinology-to-parasitic-diseases-a-perspective-on-feature-selection-and-ranking-of-vaccine-candidates
#16
Stephen J Goodswen, Paul J Kennedy, John T Ellis
Reverse vaccinology has the potential to rapidly advance vaccine development against parasites, but it is unclear which features studied in silico will advance vaccine development. Here we consider Neospora caninum which is a globally distributed protozoan parasite causing significant economic and reproductive loss to cattle industries worldwide. The aim of this study was to use a reverse vaccinology approach to compile a worthy vaccine candidate list for N. caninum, including proteins containing pathogen-associated molecular patterns to act as vaccine carriers...
September 8, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28891820/transitional-objects-to-faciliate-grieving-following-perinatal-loss
#17
Lawrence D LeDuff, Wanda T Bradshaw, Stephanie M Blake
BACKGROUND: Parents who experience a perinatal loss often leave the hospital with empty arms and no tangible mementos to validate the parenting experience. Opportunities to create parenting experiences with transitional objects exist following the infant's death. PURPOSE: This article offers suggestions for staff in units where infant loss is possible to best assist parents in optimal grieving through the offering of transitional bereavement objects. METHODS/SEARCH STRATEGY: CINAHL Complete, MEDLINE, and the Cochrane Database of Systematic Reviews were searched using the following key words-perinatal bereavement, grief, perinatal loss, transitional objects, bereavement photography-and the search was limited to 5 years and the English language...
September 7, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28885954/medical-evaluation-board-for-mental-health-condition-u-s-army-officer-medical-evaluation-board-data-by-branch-and-component
#18
William A Thomas, Eric L Doane, Robert H Gallavan, Spencer Tavares, Mark C Jones
OBJECTIVE: A retrospective review of Medical Evaluation Board (MEB) data to determine the effect of career field or Army component on the relative risk for mental health (MH) related MEBs among Army Officers, may identify specific populations for enhanced screening before accession, or groups that may require targeted preventive resources during their careers. METHOD: 4 years' of data available on Army Officers from the Department of the Army's Electronic Disability Evaluation System database, contained specific information on the officers' physical profiles, career fields, and service component...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28885859/interventions-designed-to-promote-exclusive-breastfeeding-in-high-income-countries-a-systematic-review-update
#19
Helen Skouteris, Cate Bailey, Cate Nagle, Yvonne Hauck, Lauren Bruce, Heather Morris
BACKGROUND: Worldwide, women seldom reach the recommended target of exclusive breastfeeding up to 6 months postpartum. The aim of the current study was to update a previously published review that presented a conceptual and methodological synthesis of interventions designed to promote exclusive breastfeeding up to 6 months in high-income countries. MATERIALS AND METHODS: A systematic search of leading databases was conducted for scholarly, peer-reviewed, randomized controlled trials published from June 2013 to December 2016...
September 8, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28885328/use-of-thiazolidinediones-and-risk-of-hip-fracture-in-old-people-in-a-case-control-study-in-taiwan
#20
Hsien-Feng Lin, Kuan-Fu Liao, Ching-Mei Chang, Cheng-Li Lin, Chih-Hsueh Lin, Shih-Wei Lai
Little research is available on the association between use of thiazolidinediones and hip fracture in old people in Taiwan. We conducted a population-based case-control study to examine this issue.Using the database of the Taiwan National Health Insurance Program, we identified 603 type 2 diabetic subjects 65 years or older in age with newly diagnosed hip fracture in 2000 to 2013 as cases. We randomly selected 603 type 2 diabetic subjects 65 years or older without hip fracture as the controls. Both cases and controls were matched with sex, age, comorbidities, and index year of diagnosing hip fracture...
September 2017: Medicine (Baltimore)
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