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https://www.readbyqxmd.com/read/28096066/-happiness-inventors-informing-positive-computing-technologies-through-participatory-design-with-children
#1
Svetlana Yarosh, Stephen Matthew Schueller
BACKGROUND: Positive psychological interventions for children have typically focused on direct adaptations of interventions developed for adults. As the community moves toward designing positive computing technologies to support child well-being, it is important to use a more participatory process that directly engages children's voices. OBJECTIVE: Our objectives were, through a participatory design study, to understand children's interpretations of positive psychology concepts, as well as their perspectives on technologies that are best suited to enhance their engagement with practice of well-being skills...
January 17, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28095807/comparison-of-developmental-milestone-attainment-in-early-treated-hiv-infected-infants-versus-hiv-unexposed-infants-a-prospective-cohort-study
#2
Sarah Benki-Nugent, Dalton Wamalwa, Agnes Langat, Kenneth Tapia, Judith Adhiambo, Daisy Chebet, Helen Moraa Okinyi, Grace John-Stewart
BACKGROUND: Infant HIV infection is associated with delayed milestone attainment. The extent to which effective antiretroviral therapy (ART) prevents these delays is not well defined. METHODS: Ages at attainment of milestones were compared between HIV-infected (initiated ART by age <5 months), and HIV-unexposed uninfected (HUU) infants. Kaplan Meier analyses were used to estimate and compare (log-rank tests) ages at milestones between groups. Adjusted analyses were performed using Cox proportional hazards models...
January 17, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28093555/variance-and-invariance-of-neuronal-long-term-representations
#3
REVIEW
Claudia Clopath, Tobias Bonhoeffer, Mark Hübener, Tobias Rose
The brain extracts behaviourally relevant sensory input to produce appropriate motor output. On the one hand, our constantly changing environment requires this transformation to be plastic. On the other hand, plasticity is thought to be balanced by mechanisms ensuring constancy of neuronal representations in order to achieve stable behavioural performance. Yet, prominent changes in synaptic strength and connectivity also occur during normal sensory experience, indicating a certain degree of constitutive plasticity...
March 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28093261/experimental-evaluation-of-a-new-morphological-approximation-of-the-articular-surfaces-of-the-ankle-joint
#4
Claudio Belvedere, Sorin Siegler, Andrea Ensini, Jason Toy, Paolo Caravaggi, Ramya Namani, Giulia Giannini, Stefano Durante, Alberto Leardini
The mechanical characteristics of the ankle such as its kinematics and load transfer properties are influenced by the geometry of the articulating surfaces. A recent, image-based study found that these surfaces can be approximated by a saddle-shaped, skewed, truncated cone with its apex oriented laterally. The goal of this study was to establish a reliable experimental technique to study the relationship between the geometry of the articular surfaces of the ankle and its mobility and stability characteristics and to use this technique to determine if morphological approximations of the ankle surfaces based on recent discoveries, produce close to normal behavior...
January 7, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28061552/the-role-of-nursing-professionals-in-the-management-of-patients-with-high-risk-neuroblastoma-receiving-dinutuximab-therapy
#5
Rita Secola, Araz Marachelian, Susan L Cohn, Bonnie Toy, Kathleen Neville, Meaghan Granger, Angela Brentlinger, Gina Martin
Neuroblastoma, an embryonic cancer of the sympathetic nervous system, is the most common extracranial solid tumor in childhood. Dinutuximab (formerly called ch14.18), a monoclonal antibody targeting the disialoganglioside GD2, has been shown to significantly improve survival rates in patients with high-risk neuroblastoma. However, the safe and effective use of dinutuximab therapy in these high-risk patients requires medical expertise in patient selection, treatment administration, and the monitoring and management of adverse events...
January 1, 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28048988/-improving-the-quality-of-life-of-residents
#6
Mina Ben Makhad, Cindy Faucheux-Bourdon, Amandine Guibe, Anastasia Tortevois, Christine Morel, Cathy Loirat, Agnès Bonnain
The socially interactive therapeutic robot Paro is presented in the form of a soft toy. It can benefit patients suffering from Alzheimer's as well as nurses.
January 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28044163/an-unexpected-bridge-between-chemical-bonding-indicators-and-electrical-conductivity-through-the-localization-tensor
#7
Ángel Martín Pendás, José Manuel Guevara-Vela, Daniel Menéndez Crespo, Aurora Costales, Evelio Francisco
While the modern theory of the insulating state shows that the conducting or insulating properties of a system can be extracted solely from the ground state properties via the so-called localization tensor (LT), no chemical reading of this important quantity has ever been offered. Here, a remarkable link between the LT and the bond orders as described by the delocalization indices (DIs) of chemical bonding theory is reported. This is achieved through a real space partition of the LT into intra- and interatomic contributions...
January 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28042620/summarizing-simulation-results-using-causally-relevant-states
#8
Nidhi Parikh, Madhav Marathe, Samarth Swarup
As increasingly large-scale multiagent simulations are being implemented, new methods are becoming necessary to make sense of the results of these simulations. Even concisely summarizing the results of a given simulation run is a challenge. Here we pose this as the problem of simulation summarization: how to extract the causally-relevant descriptions of the trajectories of the agents in the simulation. We present a simple algorithm to compress agent trajectories through state space by identifying the state transitions which are relevant to determining the distribution of outcomes at the end of the simulation...
May 2016: Multiagent Based Simul
https://www.readbyqxmd.com/read/28040829/application-of-life-cycle-assessment-on-electronic-waste-management-a-review
#9
Mianqiang Xue, Zhenming Xu
Electronic waste is a rich source of both valuable materials and toxic substances. Management of electronic waste is one of the biggest challenges of current worldwide concern. As an effective and prevailing environmental management tool, life cycle assessment can evaluate the environmental performance of electronic waste management activities. Quite a few scientific literatures reporting life cycle assessment of electronic waste management with significant outcomes have been recently published. This paper reviewed the trends, characteristics, research gaps, and challenges of these studies providing detailed information for practitioners involved in electronic waste management...
December 31, 2016: Environmental Management
https://www.readbyqxmd.com/read/28025128/potential-pitfalls-when-denoising-resting-state-fmri-data-using-nuisance-regression
#10
Molly G Bright, Christopher R Tench, Kevin Murphy
In resting state fMRI, it is necessary to remove signal variance associated with noise sources, leaving cleaned fMRI time-series that more accurately reflect the underlying intrinsic brain fluctuations of interest. This is commonly achieved through nuisance regression, in which the fit is calculated of a noise model of head motion and physiological processes to the fMRI data in a General Linear Model, and the "cleaned" residuals of this fit are used in further analysis. We examine the statistical assumptions and requirements of the General Linear Model, and whether these are met during nuisance regression of resting state fMRI data...
December 23, 2016: NeuroImage
https://www.readbyqxmd.com/read/28019007/proposed-revised-nomenclature-for-transfusion-related-acute-lung-injury
#11
Pearl Toy, Steven H Kleinman, Mark R Looney
A decade ago, definitions of "transfusionߚrelated acute lung injury (TRALI)" and "possible TRALI" were standardized for research and clinical diagnosis. Since then, evidence has confirmed that TRALI is often due to transfusion of white blood cell antibodies to at-risk patients, and the term "TRALI, antibody mediated" is appropriate for such cases. Other TRALI cases are non-antibody mediated. Because specific, nonantibody transfusion factors have not yet been confirmed to cause TRALI in humans, the general term "TRALI, non-antibody mediated" is appropriate for such cases...
December 26, 2016: Transfusion
https://www.readbyqxmd.com/read/28012263/robotic-gynaecologic-surgery-a-tool-or-a-toy
#12
Vasileios Minas
No abstract text is available yet for this article.
January 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28006690/cause-or-consequence-investigating-attention-bias-and-self-regulation-skills-in-children-at-risk-for-obesity
#13
Nora Mehl, Sarah Bergmann, Annette M Klein, Moritz Daum, Kai von Klitzing, Annette Horstmann
Impaired self-regulation, especially in food-specific situations, has been linked to childhood obesity. These deficits may be acquired during the development of obesity rather than being a prerequisite thereof. The current study, hence, focused on an at-risk population versus controls. Normal-weight children of obese and normal-weight parents were tested regarding attentional flexibility, emotion regulation, and inhibitory control. A sample of 50 preschoolers of obese parents (n=25) or normal-weight parents (n=25) participated in this study...
March 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28004820/detection-of-timescales-in-evolving-complex-systems
#14
Richard K Darst, Clara Granell, Alex Arenas, Sergio Gómez, Jari Saramäki, Santo Fortunato
Most complex systems are intrinsically dynamic in nature. The evolution of a dynamic complex system is typically represented as a sequence of snapshots, where each snapshot describes the configuration of the system at a particular instant of time. This is often done by using constant intervals but a better approach would be to define dynamic intervals that match the evolution of the system's configuration. To this end, we propose a method that aims at detecting evolutionary changes in the configuration of a complex system, and generates intervals accordingly...
December 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28004588/2015-annual-report-of-the-american-association-of-poison-control-centers-national-poison-data-system-npds-33rd-annual-report
#15
James B Mowry, Daniel A Spyker, Daniel E Brooks, Ashlea Zimmerman, Jay L Schauben
INTRODUCTION: This is the 33rd Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January 2015, 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 9.52 [7.40, 13.6] (median [25%, 75%]) minutes, creating a near real-time national exposure and information database and surveillance system. METHODS: We analyzed the case data tabulating specific indices from NPDS...
December 2016: Clinical Toxicology
https://www.readbyqxmd.com/read/28004222/auditory-preference-of-children-with-autism-spectrum-disorders
#16
Lynn R Gilbertson, Robert A Lutfi, Susan Ellis Weismer
Research on children with autism spectrum disorders suggests differences from neurotypical children in the preference for 'social' versus 'nonsocial' sounds. Conclusions have been based largely on the use of head-turn methodology which has various limitations as a means of establishing auditory preference. In the present study, preference was assessed by measuring the frequency with which children pressed a button to hear different sounds using an interactive toy. Contrary to prior results, both groups displayed a strong preference for the highly social sounds...
December 21, 2016: Cognitive Processing
https://www.readbyqxmd.com/read/28003533/a-unifying-comparative-phylogenetic-framework-including-traits-coevolving-across-interacting-lineages
#17
Marc Manceau, Amaury Lambert, Hélène Morlon
- Models of phenotypic evolution fit to phylogenetic comparative data are widely used to make inferences regarding the tempo and mode of trait evolution. A wide range of models is already available for this type of analysis, and the field is still under active development. One of the most needed developments concerns models that better account for the effect of within- and between-clade interspecific interactions on trait evolution, that can result from processes as diverse as competition, predation, parasitism, or mutualism...
December 20, 2016: Systematic Biology
https://www.readbyqxmd.com/read/28002091/vector-analysis-of-1-year-astigmatic-outcomes-from-a-randomized-fellow-eye-comparison-of-photorefractive-keratectomy-using-2-excimer-laser-platforms
#18
Brian C Toy, Edward E Manche
OBJECTIVE: To compare the astigmatic outcomes of photorefractive keratectomy (PRK) with a wavefront-guided (WFG) and a wavefront-optimized (WFO) excimer laser performed on two different platforms. METHODS: Setting: institutional. DESIGN: Prospective, randomized, fellow eye comparison clinical trial. PARTICIPANTS: A total of 142 eyes of 71 patients with myopia of 12 diopters (D) or less and astigmatism of 3D or less were enrolled at the Byers Eye Institute at Stanford between April 2009 and March 2011...
December 19, 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/28001376/thirdhand-smoke-new-evidence-challenges-and-future-directions
#19
Peyton Jacob, Neal L Benowitz, Hugo Destaillats, Lara Gundel, Bo Hang, Manuela Martins-Green, Georg E Matt, Penelope J E Quintana, Jonathan M Samet, Suzaynn F Schick, Prue Talbot, Noel J Aquilina, Melbourne F Hovell, Jian-Hua Mao, Todd P Whitehead
Thirdhand smoke (THS) is the contamination that persists after secondhand tobacco smoke has been emitted into air. It refers to the tobacco-related gases and particles that become embedded in materials, such as the carpet, walls, furniture, blankets, and toys. THS is not strictly smoke, but chemicals that adhere to surfaces from which they can be released back into the air, undergo chemical transformations and/or accumulate. Currently, the hazards of THS are not as well documented as the hazards of secondhand smoke (SHS)...
December 21, 2016: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/27986707/activating-esr1-mutations-differentially-impact-the-efficacy-of-er-antagonists
#20
Weiyi Toy, Hazel Weir, Pedram Razavi, Mandy Lawson, Anne U Goeppert, Anne Marie Mazzola, Aaron Smith, Joanne Wilson, Christopher Morrow, Wai Lin Wong, Elisa De Stanchina, Kathryn E Carlson, Teresa S Martin, Sharmeen Uddin, Zhiqiang Li, Sean Fanning, John A Katzenellenbogen, Geoffrey Greene, José Baselga, Sarat Chandarlapaty
Recent studies have identified somatic ESR1 mutations in patients with metastatic breast cancer (MBC) and found some of them to promote estrogen-independent activation of the receptor. The degree to which all recurrent mutants can drive estrogen-independent activities and reduced sensitivity to ER antagonists like fulvestrant is not established. In this report, we characterize the spectrum of ESR1 mutations from over 900 patients. ESR1 mutations were detected in 10%, with D538G being the most frequent (36%), followed by Y537S (14%)...
December 16, 2016: Cancer Discovery
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