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https://www.readbyqxmd.com/read/29778831/black-plastics-linear-and-circular-economies-hazardous-additives-and-marine-pollution
#1
REVIEW
Andrew Turner
Black products constitute about 15% of the domestic plastic waste stream, of which the majority is single-use packaging and trays for food. This material is not, however, readily recycled owing to the low sensitivity of black pigments to near infrared radiation used in conventional plastic sorting facilities. Accordingly, there is mounting evidence that the demand for black plastics in consumer products is partly met by sourcing material from the plastic housings of end-of-life waste electronic and electrical equipment (WEEE)...
May 17, 2018: Environment International
https://www.readbyqxmd.com/read/29776087/effect-of-form-of-obstacle-on-speed-of-crowd-evacuation
#2
Ryosuke Yano
This paper investigates the effect of the form of an obstacle on the time that a crowd takes to evacuate a room, using a toy model. Pedestrians are modeled as active soft matter moving toward a point with intended velocities. An obstacle is placed in front of the exit, and it has one of four shapes: a cylindrical column, a triangular prism, a quadratic prism, or a diamond prism. Numerical results indicate that the evacuation-completion time depends on the shape of the obstacle. Obstacles with a circular cylinder (C...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29767802/sitting-together-and-reaching-to-play-start-play-protocol-for-a-multisite-randomized-controlled-efficacy-trial-on-intervention-for-infants-with-neuromotor-disorders
#3
Regina T Harbourne, Stacey C Dusing, Michele A Lobo, Sarah Westcott-McCoy, James Bovaird, Susan Sheridan, James C Galloway, Hui-Ju Chang, Lin-Ya Hsu, Natalie Koziol, Emily C Marcinowski, Iryna Babik
Background: There is limited research examining the efficacy of early physical therapy on infants with neuromotor dysfunction. In addition, most early motor interventions have not been directly linked to learning, despite the clear association between motor activity and cognition during infancy. Objective: The aim of this project is to evaluate the efficacy of Sitting Together And Reaching To Play (START-Play), an intervention designed to target sitting, reaching, and motor-based problem solving to advance global development in infants with motor delays or neuromotor dysfunction...
June 1, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29762113/cervicothoracic-pedicle-morphometry-using-an-osteological-collection-to-characterize-trends-in-pedicle-size
#4
Mhamad Faour, Charles C Yu, Navkirat Bajwa, Jason O Toy, Uri M Ahn, Nicholas U Ahn
Pedicle screws are a common treatment option for spinal instability. Despite their popularity, pedicle screws carry the risk of transpedicular violation with subsequent neural and vascular damage. This study measured the pedicle dimensions of 500 dry specimens in an osteological collection. The data provide the orthopedic spine surgeon with an accurate measure of pedicle morphometry in light of previously limited and contradictory results. The study demonstrates that pedicle height at the cervicothoracic junction tends to increase with body height, particularly for females...
2018: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/29761854/parenting-adolescents-with-asd-a-multimethod-study
#5
Lotte van Esch, Steven Vanmarcke, Eva Ceulemans, Karla Van Leeuwen, Ilse Noens
A number of studies have concluded that parents of children with ASD experience high levels of parenting stress. However, little is known about their parenting behaviors. Especially few studies investigated parenting in adolescence, although this period is associated with additional challenges for both adolescents and their parents. In the present study, a multi-method approach was used, combining data from a self-report questionnaire and observation of mother-child interactions during different semi-structured (e...
May 15, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29760669/ontological-constraints-in-children-s-inductive-inferences-evidence-from-a-comparison-of-inferences-within-animals-and-vehicles
#6
Andrzej Tarlowski
There is a lively debate concerning the role of conceptual and perceptual information in young children's inductive inferences. While most studies focus on the role of basic level categories in induction the present research contributes to the debate by asking whether children's inductions are guided by ontological constraints. Two studies use a novel inductive paradigm to test whether young children have an expectation that all animals share internal commonalities that do not extend to perceptually similar inanimates...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29759786/the-value-proposition-of-remote-catheter-navigation-efficient-tools-versus-expensive-toys
#7
EDITORIAL
Bruce D Lindsay
No abstract text is available yet for this article.
August 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29754080/lead-in-spray-paint-and-painted-surfaces-in-playgrounds-and-public-areas-in-israel-results-of-a-pilot-study
#8
Tamar Berman, Zohar Barnett-Itzhaki, Shay Reicher, Ruti Ardi, Yaniv Shammai, Lior Aruas, Maya Negev
Exposure to low levels of lead in children can cause cognitive deficits (reduced IQ) and behavioral changes such as reduced attention span and increased antisocial behavior. There are no mandatory limits on lead in paint in Israel, with the exception of paints used on toys and children's furniture. However, paints in playgrounds and public areas may be a source of exposure to lead in young children. In this study, we quantified lead concentrations in painted surfaces in public playgrounds and public areas, and in spray paints in Israel, using X-ray fluorescence (XRF)...
May 10, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29738768/differential-effects-of-voluntary-wheel-running-and-toy-rotation-on-the-mrna-expression-of-neurotrophic-factors-and-fkbp5-in-a-post-traumatic-stress-disorder-rat-model-with-the-shuttle-box-task
#9
Masaaki Tanichi, Hiroyuki Toda, Kunio Shimizu, Minori Koga, Taku Saito, Shingo Enomoto, Shuken Boku, Fumiho Asai, Yumi Mitsui, Masanori Nagamine, Masanori Fujita, Aihide Yoshino
Life-threatening experiences can result in the development of post-traumatic stress disorder. We have developed an animal model for post-traumatic stress disorder (PTSD) using a shuttle box in rats. In this paradigm, the rats were exposed to inescapable foot-shock stress (IS) in a shuttle box, and then an avoidance/escape task was performed in the same box 2 weeks after IS. A previous study using this paradigm revealed that environmental enrichment (EE) ameliorated avoidance/numbing-like behaviors, but not hyperarousal-like behaviors, and EE also elevated hippocampal brain-derived neurotrophic factor (BDNF) expression...
May 5, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29735743/the-substrate-specificity-of-eukaryotic-cytosolic-chaperonin-cct
#10
REVIEW
Keith R Willison
The cytosolic chaperonin CCT (chaperonin containing TCP-1) is an ATP-dependent double-ring protein machine mediating the folding of members of the eukaryotic cytoskeletal protein families. The actins and tubulins are obligate substrates of CCT because they are completely dependent on CCT activity to reach their native states. Genetic and proteomic analysis of the CCT interactome in the yeast Saccharomyces cerevisiae revealed a CCT network of approximately 300 genes and proteins involved in many fundamental biological processes...
June 19, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29729680/theileria-parva-antigens-recognized-by-cd8-t-cells-show-varying-degrees-of-diversity-in-buffalo-derived-infected-cell-lines
#11
Tatjana Sitt, Roger Pelle, Maurine Chepkwony, W Ivan Morrison, Philip Toye
The extent of sequence diversity among the genes encoding 10 antigens (Tp1-10) known to be recognized by CD8+ T lymphocytes from cattle immune to Theileria parva was analysed. The sequences were derived from parasites in 23 buffalo-derived cell lines, three cattle-derived isolates and one cloned cell line obtained from a buffalo-derived stabilate. The results revealed substantial variation among the antigens through sequence diversity. The greatest nucleotide and amino acid diversity were observed in Tp1, Tp2 and Tp9...
May 6, 2018: Parasitology
https://www.readbyqxmd.com/read/29717498/infrared-thermal-imaging-positive-and-negative-emotions-modify-the-skin-temperatures-of-monkey-and-ape-faces
#12
Hélène Chotard, Stephanos Ioannou, Marina Davila-Ross
Facial thermography has enabled researchers to noninvasively and continuously measure the changes of a range of emotional states in humans. The present work used this novel technology to study the effect of positive and negative emotions in nonhuman primates by focusing on four facial areas (the peri-orbital area, the nose bridge, the nose tip, and the upper lip). Monkeys and apes were examined for positive emotions (during interactions with toys and during tickling) and for negative emotions (during food delay and teasing)...
May 1, 2018: American Journal of Primatology
https://www.readbyqxmd.com/read/29716723/experimental-evaluation-of-current-and-novel-approximations-of-articular-surfaces-of-the-ankle-joint
#13
Claudio Belvedere, Sorin Siegler, Andrea Ensini, Jason Toy, Paolo Caravaggi, Ramya Namani, Luca Giuseppe Princi, Stefano Durante, Alberto Leardini
Kinematics and flexibility properties of both natural and replaced ankle joints are affected by the geometry of the articulating surfaces. Recent studies proposed an original saddle-shaped, skewed, truncated cone with laterally oriented apex, as tibiotalar contact surfaces for ankle prosthesis. The goal of this study was to compare in vitro this novel design with traditional cylindrical or medially centered conic geometries in terms of their ability to replicate the natural ankle joint mechanics. Ten lower limb cadaver specimens underwent a validated process of custom design for the replacement of the natural ankle joint...
April 24, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29716583/immunization-with-one-theileria-parva-strain-results-in-similar-level-of-ctl-strain-specificity-and-protection-compared-to-immunization-with-the-three-component-muguga-cocktail-in-mhc-matched-animals
#14
Lucilla Steinaa, Nicholas Svitek, Elias Awino, Thomas Njoroge, Rosemary Saya, Ivan Morrison, Philip Toye
BACKGROUND: The tick-borne protozoan parasite Theileria parva causes a usually fatal cattle disease known as East Coast fever in sub-Saharan Africa, with devastating consequences for poor small-holder farmers. Immunity to T. parva, believed to be mediated by a cytotoxic T lymphocyte (CTL) response, is induced following natural infection and after vaccination with a live vaccine, known as the Infection and Treatment Method (ITM). The most commonly used version of ITM is a combination of parasites derived from three isolates (Muguga, Kiambu 5 and Serengeti-transformed), known as the "Muguga cocktail"...
May 2, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29713341/use-of-telemedicine-in-addiction-treatment-current-practices-and-organizational-implementation-characteristics
#15
Todd Molfenter, Roger Brown, Andrew O'Neill, Ed Kopetsky, Alexander Toy
Telemedicine applications offer innovative approaches for treating and reducing the effects of substance use disorders (SUDs). This analysis assessed the interest in and use of 11 telemedicine applications in a sample of 363 SUD organizations in the United States of America. Fifty percent of the organizations expressed high rates of interest in seven of the telemedicine applications, demonstrating the appeal of telemedicine within this field. The top three self-reported telemedicine applications being used were (1) computerized screening/assessments (44...
2018: International Journal of Telemedicine and Applications
https://www.readbyqxmd.com/read/29706991/on-synchronizing-coupled-retinogeniculocortical-pathways-a-toy-model
#16
B L Mayer, L H A Monteiro
A Newman-Watts graph is formed by including random links in a regular lattice. Here, the emergence of synchronization in coupled Newman-Watts graphs is studied. The whole neural network is considered as a toy model of mammalian visual pathways. It is composed by four coupled graphs, in which a coupled pair represents the lateral geniculate nucleus and the visual cortex of a cerebral hemisphere. The hemispheres communicate with each other through a coupling between the graphs representing the visual cortices...
2018: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/29702080/continuation-of-long-acting-reversible-contraceptives-among-medicaid-patients
#17
Max J Romano, Patryce Toye, Loral Patchen
OBJECTIVE: Our objective was to compare continuation and complication rates of subdermal etonogestrel implants and intrauterine devices (IUDs) using Medicaid insurance claims. STUDY DESIGN: We performed a retrospective cohort study using insurance claims data for 15- to 44-year-old subjects receiving implants or IUDs from 2012 to 2015 in a Medicaid managed care organization in Washington, DC, and Maryland. We performed a planned Kaplan-Meier survival analysis for long-acting reversible contraceptive (LARC) continuation, defined as the absence of a claim for LARC removal, during periods of continuous insurance plan enrollment...
April 24, 2018: Contraception
https://www.readbyqxmd.com/read/29700043/enhancement-of-red-blood-cell-transfusion-compatibility-using-crispr-mediated-erythroblast-gene-editing
#18
Joseph Hawksworth, Timothy J Satchwell, Marjolein Meinders, Deborah E Daniels, Fiona Regan, Nicole M Thornton, Marieangela C Wilson, Johannes Gg Dobbe, Geert J Streekstra, Kongtana Trakarnsanga, Kate J Heesom, David J Anstee, Jan Frayne, Ashley M Toye
Regular blood transfusion is the cornerstone of care for patients with red blood cell (RBC) disorders such as thalassaemia or sickle-cell disease. With repeated transfusion, alloimmunisation often occurs due to incompatibility at the level of minor blood group antigens. We use CRISPR-mediated genome editing of an immortalised human erythroblast cell line (BEL-A) to generate multiple enucleation competent cell lines deficient in individual blood groups. Edits are combined to generate a single cell line deficient in multiple antigens responsible for the most common transfusion incompatibilities: ABO (Bombay phenotype), Rh (Rhnull ), Kell ( K 0 ), Duffy (Duffynull ), GPB (S- s- U- )...
April 26, 2018: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/29696601/a-simple-mathematical-model-inspired-by-the-purkinje-cells-from-delayed-travelling-waves-to-fractional-diffusion
#19
Serena Dipierro, Enrico Valdinoci
Recently, several experiments have demonstrated the existence of fractional diffusion in the neuronal transmission occurring in the Purkinje cells, whose malfunctioning is known to be related to the lack of voluntary coordination and the appearance of tremors. Also, a classical mathematical feature is that (fractional) parabolic equations possess smoothing effects, in contrast with the case of hyperbolic equations, which typically exhibit shocks and discontinuities. In this paper, we show how a simple toy-model of a highly ramified structure, somehow inspired by that of the Purkinje cells, may produce a fractional diffusion via the superposition of travelling waves that solve a hyperbolic equation...
April 25, 2018: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/29694086/elliptic-double-box-integrals-massless-scattering-amplitudes-beyond-polylogarithms
#20
Jacob L Bourjaily, Andrew J McLeod, Marcus Spradlin, Matt von Hippel, Matthias Wilhelm
We derive an analytic representation of the ten-particle, two-loop double-box integral as an elliptic integral over weight-three polylogarithms. To obtain this form, we first derive a fourfold, rational (Feynman-)parametric representation for the integral, expressed directly in terms of dual-conformally invariant cross ratios; from this, the desired form is easily obtained. The essential features of this integral are illustrated by means of a simplified toy model, and we attach the relevant expressions for both integrals in ancillary files...
March 23, 2018: Physical Review Letters
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