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Ariane Lenzner, Bärbel Vieth, Andreas Luch
No abstract text is available yet for this article.
March 16, 2018: Archives of Toxicology
Lilian Cristina Pereira, Murilo Pazin, Mariana Furio Franco-Bernardes, Airton da Cunha Martins, Gustavo Rafael Mazzaron Barcelos, Márcio Cesar Pereira, João Paulo Mesquita, Jairo Lisboa Rodrigues, Fernando Barbosa, Daniel Junqueira Dorta
Nanotechnology is a growing branch of science that deals with the development of structural features bearing at least one dimension in the nano range. More specifically, nanomaterials are defined as objects with dimensions that range from 1 to 100 nm, which give rise to interesting properties. In particular, silver and titanium nanoparticles (AgNPs and TiNPs, respectively) are known for their biological and biomedical properties and are often used in consumer products such as cosmetics, food additives, kitchen utensils, and toys...
May 2018: Journal of Trace Elements in Medicine and Biology
Manuela Lavelli, Marinella Majorano, Letizia Guerzoni, Alessandra Murri, Chiara Barachetti, Domenico Cuda
This study examined (a) the functions and modalities of maternal and child communication during interaction between mothers and children with cochlear implants (CIs), comparing them with mothers and normally hearing (NH) children, and (b) the effectiveness of maternal support strategies in eliciting adequate answers in children with CI. Twenty preschoolers with CIs (M = 40 months) and 40 NH children - 20 matched by chronological age (CANH, M = 40 months) and 20 matched by hearing age (HANH, M = 25 months) - were videotaped during shared book reading and toy play with their mothers...
March 5, 2018: Journal of Communication Disorders
Toye Gabriel Olajide, Kayode Shuaib Aremu, Olaide T Esan, Adepeju Oluwatona Dosunmu, Mustapha Muhammad Raji
Background: Self-medication is a common habit in our country; Nigeria, especially among patients with otorhinolaryngological disorders. Medication when taken wrongly may bring dire consequences to the individual, such as masking developing diseases and may cause many other undesirable effects. The aim of this study was to determine the prevalence and to analyze topical ear drop self-medication practices among respondents attending the Ear, Nose, and Throat Clinic of Federal Teaching Hospital Ido Ekiti, Nigeria...
April 2018: Annals of African Medicine
Linda Gerencsér, Nóra Bunford, Alexandra Moesta, Ádám Miklósi
Although there is ample data indicating that reward processing plays an important role in human psychopathologies and pharmaco- and psychotherapy treatment response, the corresponding animal-model research needs to be extended to models whose motivational and social dispositions are better generalizable than those of the traditional models. Accordingly, our aim was to develop and assess the reliability and validity of an owner-report rating scale of reward responsiveness in domestic dogs (N = 2149) and then to examine individual differences in reward responsiveness...
March 13, 2018: Scientific Reports
Richard C Waters, Jennifer M Toy, Adam Drechsler
Objective: Translating clinical evidence to daily practice remains a challenge and may improve with clinical pathways. We assessed interest in and usability of clinical pathways by primary care professionals. Methods: An online survey was created. Interest in pathways for patient care and learning was assessed at start and finish. Participants completed baseline questions then pathway-associated question sets related to management of 2 chronic diseases. Perceived pathway usability was assessed using the system usability scale...
February 26, 2018: Journal of the American Medical Informatics Association: JAMIA
Toy Lee, Derrick Sanderson, Paula Doyle, Gunhilde Buchsbaum
BACKGROUND: Rates of administration of intravenous sodium fluorescein during cystoscopy have increased since indigotindisulfonate sodium was removed from the market in 2014. Although sodium fluorescein has been extensively evaluated and found to be safe, side effects including anaphylaxis have been observed, with an incidence between 0.05% and 1.0%. CASE: We present a case of anaphylactic shock after administration of intravenous sodium fluorescein for the assessment of ureteral efflux in a patient with a history of frequent severe allergic reactions undergoing urethral lysis and cystoscopy for urinary retention...
March 8, 2018: Obstetrics and Gynecology
Gregor Kachel, Richard Moore, Michael Tomasello
In the current study, 24- to 27-month-old children (N = 37) used pointing gestures in a cooperative object choice task with either peer or adult partners. When indicating the location of a hidden toy, children pointed equally accurately for adult and peer partners but more often for adult partners. When choosing from one of three hiding places, children used adults' pointing to find a hidden toy significantly more often than they used peers'. In interaction with peers, children's choice behavior was at chance level...
March 12, 2018: Developmental Science
Srdjan Cirovic, Robert Lloyd, Jelena Jovanovik, Holger A Volk, Clare Rusbridge
BACKGROUND: Syringomyelia is a pathological condition in which fluid-filled cavities (syringes) form and expand in the spinal cord. Syringomyelia is often linked with obstruction of the craniocervical junction and a Chiari malformation, which is similar in both humans and animals. Some brachycephalic toy breed dogs such as Cavalier King Charles Spaniels (CKCS) are particularly predisposed. The exact mechanism of the formation of syringomyelia is undetermined and consequently with the lack of clinical explanation, engineers and mathematicians have resorted to computer models to identify possible physical mechanisms that can lead to syringes...
March 9, 2018: BMC Veterinary Research
Heather A Feldner, Samuel W Logan, James C Galloway
AIM: Rehabilitation professionals are increasingly recognizing mobility as a basic human right and endorsing the efficacy of early powered mobility for children with mobility impairments to foster independence, promote socialization with peers and facilitate participation in family and community life. However, the relationship between mobility and technology provision, when considered in the context of lived experiences of children with mobility impairments and their families, is complex and understudied...
March 9, 2018: Disability and Rehabilitation. Assistive Technology
Hui-Feng Zhang, Lan Shuai, Jin-Song Zhang, Yu-Feng Wang, Teng-Fei Lu, Xin Tan, Jing-Xue Pan, Li-Xiao Shen
Background: Previous studies have found that schoolchildren with attention-deficit/hyperactivity disorder (ADHD) showed difficulties in neuropsychological function. This study aimed to assess neuropsychological function in Chinese preschoolers with ADHD using broad neuropsychological measures and rating scales and to test whether the pattern and severity of neuropsychological weakness differed among ADHD presentations in preschool children. Methods: The 226 preschoolers (163 with ADHD and 63 controls) with the age of 4-5 years were included and assessed using the Behavior Rating Scale of Executive Function-Preschool Version (BRIEF-P) and a series of tests to investigate neuropsychological function...
March 20, 2018: Chinese Medical Journal
Yunhui Ge, Vincent Alvin Voelz
The Bayesian Inference of Conformational Populations (BICePs) algorithm reconciles theoretical predictions of conformational state populations with sparse and/or noisy experimental measurements. Among its key advantages is the ability to perform objective model selection through a quantity we call the BICePs score, which reflects the integrated posterior evidence in favor of a given model, computed through free energy estimation methods. Here, we explore how the BICePs score can be used for force field validation and parameterization...
March 8, 2018: Journal of Physical Chemistry. B
Marcus Shaker, Tsuzumi Kanaoka, Robert Gp Murray, Dana Toy, Susan Shaker, Aurora Drew
No abstract text is available yet for this article.
February 27, 2018: Journal of Allergy and Clinical Immunology in Practice
Mahin Hashemipour, Roya Kelishadi, Mohammad Mehdi Amin, Karim Ebrahim
Considerable increase in the prevalence of precocious puberty (PP) during the last decade has raised a lot of concerns. Some environmental endocrine disruptor chemicals (EDCs), such as phthalate esters, have intrinsic estrogen activity or increase endogenous sex hormone levels leading to PP. This study was conducted to investigate the association between exposure to phthalate esters and PP in a sample of girls. Plasma levels of seven phthalate ester metabolites were measured in 87 girls with PP and 63 age- and sex-matched controls by dispersive liquid-liquid microextraction and GC/MS analysis...
March 1, 2018: Environmental Science and Pollution Research International
Paula Valenzuela-Leon, Ina Dobrinski
Phthalate esters are plasticizers that impart flexibility to polvinylchloride plastics. As they are not covalently bound, they can leach from a wide range of products, including food containers, medical devices, clothing, and toys, leading to widespread environmental exposure. Phthalate toxicity has been linked to male infertility by disrupting testosterone production and testis development. Phthalates also impair proliferation and viability of spermatogonial stem cells (SSC), the role of which is to support lifelong spermatogenesis...
July 2017: Environmental Epigenetics
Martin Marek, Matej Badin, Martin Plesch
Gee-Haw Whammy Diddle is a seemingly simple mechanical toy consisting of a wooden stick and a second stick that is made up of a series of notches with a propeller at its end. When the wooden stick is pulled over the notches, the propeller starts to rotate. Despite its simplicity, physical principles governing the motion of the stick and the propeller are rather complicated and interesting. Here we provide a thorough analysis of the system and parameters influencing the motion. We show that contrary to the results published on this topic so far, neither elliptic motion of the stick nor frequency synchronization is needed for starting a stable motion of the propeller...
February 27, 2018: Scientific Reports
Ashley P Liggett, Regina Nastri, Christopher A Podlesnik
Resurgence and reinstatement are laboratory models of relapse following treatments for problem behavior that arrange alternative sources of reinforcement, such as differential reinforcement of alternative behavior and noncontingent reinforcement. Resurgence models the elimination or reduction of reinforcers during treatment and reinstatement models the re-presentation of reinforcers previously maintaining problem behavior. The present study examined individual and combined effects of resurgence and reinstatement in a translational model of treatment relapse with three children diagnosed with Autism Spectrum Disorder...
February 27, 2018: Journal of the Experimental Analysis of Behavior
Wanding Yang, Michael Jones, Sameer Mallick
Delayed diagnosis of tracheobronchial foreign body (FB) aspiration is not uncommon in children. It occurs when symptoms are underappreciated and/or radiological findings are overlooked. In such cases serious complications can arise, which make the diagnosis and removal of the FB much more difficult. Here, we present a case where FB aspiration was misdiagnosed as asthma after a radio-opaque FB on the chest radiograph was missed, leading to formation of a tracheo-oesophageal fistula as a rare delayed complication...
February 2018: Journal of Surgical Case Reports
D Ito, C Ishikawa, N D Jeffery, K Ono, M Tsuboi, K Uchida, O Yamato, M Kitagawa
A 13-month-old female Toy Poodle was presented for progressive ataxia and intention tremors of head movement. The diagnosis of Sandhoff's disease (GM2 gangliosidosis) was confirmed by deficient β-N-acetylhexosaminidase A and B activity in circulating leukocytes and identification of the homozygous mutation (HEXB: c.283delG). White matter in the cerebrum and cerebellum was hyperintense on T2-weighted and fluid-attenuated inversion recovery magnetic resonance images. Over the next 2 years, the white matter lesions expanded, and bilateral lesions appeared in the cerebellum and thalamus, associated with clinical deterioration...
February 25, 2018: Journal of Veterinary Internal Medicine
Christoph Wiedmer, Andrea Buettner
Based on the observation that the characteristic odour of inflatable aquatic toys for children is predominantly caused by residues of hazardous organic solvents, the concentrations of cyclohexanone, isophorone and phenol were determined in a selection of 20 products obtained from online suppliers located in Germany. Analytes were extracted with dichloromethane after the addition of non-labelled internal standards, and the volatile fraction was isolated using solvent-assisted flavour evaporation (SAFE). Extracts were then concentrated by Vigreux distillation and analysed by means of gas chromatography with mass spectrometric detection (GC-MS)...
February 20, 2018: Analytical and Bioanalytical Chemistry
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