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https://www.readbyqxmd.com/read/28645086/toddler-exposure-to-flame-retardant-chemicals-magnitude-health-concern-and-potential-risk-or-protective-factors-of-exposure-observational-studies-summarized-in-a-systematic-review
#1
REVIEW
Eva J Sugeng, Marijke de Cock, Linda J Schoonmade, Margot van de Bor
Endocrine disrupting flame retardant (FR) chemicals form a human health concern, that is investigated mostly from the perspective of adult- and early life exposure. No overview of studies on toddler exposure and health effects exist. However, toddlerhood is a critical developmental period and toddlers are at increased risk for exposure because of their age-specific behavior. This systematic review encompasses toddler FR exposure studies in three countries, associated health effects and potential environmental, demographic, or behavioral risk- or protective factors for toddler exposure...
June 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28643355/ultra-short-echo-time-images-quantify-high-liver-iron
#2
Eamon K Doyle, Kristin Toy, Bertin Valdez, Jonathan M Chia, Thomas Coates, John C Wood
PURPOSE: 1.5T gradient echo-based R2∗ estimates are standard-of-care for assessing liver iron concentration (LIC). Despite growing popularity of 3T, echo time (TE) limitations prevent 3T liver iron quantitation in the upper half of the clinical range (LIC ⪆20 mg/g). In this work, a 3D radial pulse sequence was assessed to double the dynamic range of 3T LIC estimates. THEORY AND METHODS: The minimum TE limits the dynamic range of pulse sequences to estimate R2∗...
June 22, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28636053/evidence-of-bad-recycling-practices-bfrs-in-children-s-toys-and-food-contact-articles
#3
A Guzzonato, F Puype, S J Harrad
Brominated flame retardants (BFRs) have been used intentionally in a wide range of plastics, but are now found in an even wider range of such materials (including children's toys and food contact articles) as a result of recycling practices that mix BFR-containing waste plastics with "virgin" materials. In this study Br was quantified in toy and food contact samples on the assumption that its concentration can be used as a metric for BFR contamination. Subsequently, compound specific determination of BFRs was performed to evaluate the validity of the aforementioned assumption, crucial to render rapid, inexpensive, in situ Br determination in non-laboratory environments (such as waste handling facilities) a viable option for sorting wastes according to their BFR content...
June 21, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28634167/improved-toys-to-identify-pediatric-complexity-in-the-administrative-data-sandbox
#4
Katherine A Auger, Ellen A Lipstein
No abstract text is available yet for this article.
June 20, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28630703/energy-requirements-for-growth-in-the-yorkshire-terrier
#5
Janet E Alexander, Alison Colyer, Penelope J Morris
The 2006 National Research Council (NRC) equation calculating puppy energy requirements does not account for reported breed differences in growth pattern. Energy requirements of toy breed puppies are unknown and it is unclear whether feeding guidelines should differ between breeds. Energy requirements of Yorkshire terrier (YT) puppies were observed over their first year of life and compared with those predicted by the NRC and those previously observed in large (Labrador retriever) and medium (miniature Schnauzer; MS) breed puppies...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28625854/promoting-healthier-children-s-meals-at-quick-service-and-full-service-restaurants-results-from-a-pilot-and-feasibility-study
#6
Nanette V Lopez, Sara C Folta, Meaghan E Glenn, Vanessa M Lynskey, Anjali A Patel, Stephanie Anzman-Frasca
High-calorie restaurant foods contribute to childhood overweight. Increased consumer demand for healthier kids' meals may motivate the restaurant industry to provide additional healthy options. This study pilot-tested a combination of four strategies (toy incentive, placemats, server prompts, signage) designed to increase demand for healthier kids' meals, which were defined as those eligible for the National Restaurant Association's Kids LiveWell program. Relative sales of healthier kids' meals were examined before (n = 3473 total kids' meal orders) and during Month 1 (n = 3546 total kids' meal orders) and Month 2 of implementation (n = 3645 total kids' meal orders) of an 8-week intervention in two locations each of a quick-service (QSR) and full-service (FSR) restaurant chain...
June 15, 2017: Appetite
https://www.readbyqxmd.com/read/28618544/dynamics-of-a-mechanical-system-with-multiple-degrees-of-freedom-out-of-thermal-equilibrium
#7
A Feigel
Out of thermal equilibrium, an environment imposes effective mechanical forces on nanofabricated devices as well as on microscopic chemical or biological systems. Here we address the question of how to calculate these forces together with the response of the system from first principles. We show that an ideal gaslike environment, even near thermal equilibrium, can enforce a specific steady state on the system by creating effective potentials in otherwise homogeneous space. An example of stable and unstable rectifications of thermal fluctuations is presented using a modified Feynman-Smoluchowski ratchet with two degrees of freedom...
May 2017: Physical Review. E
https://www.readbyqxmd.com/read/28611889/evaluating-the-laboratory-risk-indicator-to-differentiate-cellulitis-from-necrotizing-fasciitis-in-the-emergency-department
#8
Michael M Neeki, Fanglong Dong, Christine Au, Jake Toy, Nima Khoshab, Carol Lee, Eugene Kwong, Ho Wang Yuen, Jonathan Lee, Arbi Ayvazian, Pamela Lux, Rodney Borger
INTRODUCTION: Necrotizing fasciitis (NF) is an uncommon but rapidly progressive infection that results in gross morbidity and mortality if not treated in its early stages. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score is used to distinguish NF from other soft tissue infections such as cellulitis or abscess. This study analyzed the ability of the LRINEC score to accurately rule out NF in patients who were confirmed to have cellulitis, as well as the capability to differentiate cellulitis from NF...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28611888/efficacy-and-safety-of-tranexamic-acid-in-prehospital-traumatic-hemorrhagic-shock-outcomes-of-the-cal-pat-study
#9
Michael M Neeki, Fanglong Dong, Jake Toy, Reza Vaezazizi, Joe Powell, Nina Jabourian, Alex Jabourian, David Wong, Richard Vara, Kathryn Seiler, Troy W Pennington, Joe Powell, Chris Yoshida-McMath, Shanna Kissel, Katharine Schulz-Costello, Jamish Mistry, Matthew S Surrusco, Karen R O'Bosky, Daved Van Stralen, Daniel Ludi, Karl Sporer, Peter Benson, Eugene Kwong, Richard Pitts, John T Culhane, Rodney Borger
INTRODUCTION: The California Prehospital Antifibrinolytic Therapy (Cal-PAT) study seeks to assess the safety and impact on patient mortality of tranexamic acid (TXA) administration in cases of trauma-induced hemorrhagic shock. The current study further aimed to assess the feasibility of prehospital TXA administration by paramedics within the framework of North American emergency medicine standards and protocols. METHODS: This is an ongoing multi-centered, prospective, observational cohort study with a retrospective chart-review comparison...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28610778/a-comparison-between-non-powder-gun-and-powder-gun-injuries-in-a-young-pediatric-population
#10
Jennifer J Freeman, Marielena Bachier-Rodriguez, Jessica Staszak, Alexander Feliz
INTRODUCTION: Non-powder guns (NPG) are viewed as toys for children by the general public. Literature on firearm injuries in the pediatric population is increasing, however there are still large gaps in the published literature regarding NPG. We intended to identify and compare the epidemiology, circumstances of injury and outcomes of children with NPG versus powder-gun injuries (GSW). PATIENTS AND METHODS: We performed a 6-year retrospective analysis of children 0-14 years old treated for NPG and GSW injuries at our level one pediatric trauma center...
May 29, 2017: Injury
https://www.readbyqxmd.com/read/28604052/lifespan-changes-in-attention-revisited-everyday-visual-search
#11
Allison A Brennan, Alison J Bruderer, Teresa Liu-Ambrose, Todd C Handy, James T Enns
This study compared visual search under everyday conditions among participants across the life span (healthy participants in 4 groups, with average age of 6 years, 8 years, 22 years, and 75 years, and 1 group averaging 73 years with a history of falling). The task involved opening a door and stepping into a room find 1 of 4 everyday objects (apple, golf ball, coffee can, toy penguin) visible on shelves. The background for this study included 2 well-cited laboratory studies that pointed to different cognitive mechanisms underlying each end of the U-shaped pattern of visual search over the life span (Hommel et al...
June 2017: Canadian Journal of Experimental Psychology, Revue Canadienne de Psychologie Expérimentale
https://www.readbyqxmd.com/read/28601602/abstinence-environment-contributes-to-age-differences-in-reinstatement-of-cocaine-seeking-between-adolescent-and-adult-male-rats
#12
Chen Li, Kyle J Frantz
RATIONALE: Extinction responding and cue-induced reinstatement of cocaine seeking after 60-days of forced abstinence are attenuated in male rats that self-administered cocaine during adolescence, compared with adults. Given that environmental enrichment during abstinence decreases reinstatement among adults, a possible explanation for attenuated reinstatement among adolescents is that standard pair-housing in prior studies creates a more stimulating environment for younger rats. OBJECTIVE: Therefore, we tested whether standard pair-housing is necessary for the attenuated reinstatement among adolescents by determining whether an impoverished environment during abstinence would increase reinstatement among adolescents, up to adult levels...
July 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28600922/the-object-of-my-desire-five-year-olds-rapidly-reason-about-a-speaker-s-desire-during-referential-communication
#13
Valerie San Juan, Craig G Chambers, Jared Berman, Chelsea Humphry, Susan A Graham
Two experiments examined whether 5-year-olds draw inferences about desire outcomes that constrain their online interpretation of an utterance. Children were informed of a speaker's positive (Experiment 1) or negative (Experiment 2) desire to receive a specific toy as a gift before hearing a referentially ambiguous statement ("That's my present") spoken with either a happy or sad voice. After hearing the speaker express a positive desire, children (N=24) showed an implicit (i.e., eye gaze) and explicit ability to predict reference to the desired object when the speaker sounded happy, but they showed only implicit consideration of the alternate object when the speaker sounded sad...
June 7, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28596066/tools-or-toys-the-20-year-anniversary-of-the-nonfluoroscopic-mapping-system-dilemma
#14
José Luis Merino
No abstract text is available yet for this article.
June 5, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28587152/long-term-physiologic-and-behavioural-effects-of-housing-density-and-environmental-resource-provision-for-adult-male-and-female-sprague-dawley-rats
#15
Christopher J Pinelli, Francesco Leri, Patricia V Turner
There is considerable interest in refining laboratory rodent environments to promote animal well-being, as well as research reproducibility. Few studies have evaluated the long term impact of enhancing rodent environments with resources and additional cagemates. To that end, male and female Sprague Dawley (SD) rats were housed singly (n = 8/sex), in pairs (n = 16/sex), or in groups of four (n = 16/sex) for five months. Single and paired rats were housed in standard cages with a nylon chew toy, while group-housed rats were kept in double-wide cages with two PVC shelters and a nylon chew toy and were provided with food enrichment three times weekly...
June 1, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28584125/drosophila-pax6-promotes-development-of-the-entire-eye-antennal-disc-thereby-ensuring-proper-adult-head-formation
#16
Jinjin Zhu, Sneha Palliyil, Chen Ran, Justin P Kumar
Paired box 6 (Pax6) is considered to be the master control gene for eye development in all seeing animals studied so far. In vertebrates, it is required not only for lens/retina formation but also for the development of the CNS, olfactory system, and pancreas. Although Pax6 plays important roles in cell differentiation, proliferation, and patterning during the development of these systems, the underlying mechanism remains poorly understood. In the fruit fly, Drosophila melanogaster, Pax6 also functions in a range of tissues, including the eye and brain...
June 6, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28583110/jack-stone-in-the-bladder-case-report-of-a-rare-entity
#17
Duminda Subasinghe, Serozsha Goonewardena, Vickneswaran Kathiragamathamby
BACKGROUND: Jackstone is a bladder stone that has a similar appearance to toy jacks. However review of the English language medical literature revealed only a few previous reports of jackstone calculus. CASE PRESENTATION: We report a case in which a large jackstone calculus was incidentally detected during the evaluation of 67 year old male presenting with lower urinary tract symptoms. X-Ray kidney, ureter, bladder showed a large irregular shaped radio-opaque shadow in the pelvic region...
June 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28574992/a-state-space-approach-for-piecewise-linear-recurrent-neural-networks-for-identifying-computational-dynamics-from-neural-measurements
#18
Daniel Durstewitz
The computational and cognitive properties of neural systems are often thought to be implemented in terms of their (stochastic) network dynamics. Hence, recovering the system dynamics from experimentally observed neuronal time series, like multiple single-unit recordings or neuroimaging data, is an important step toward understanding its computations. Ideally, one would not only seek a (lower-dimensional) state space representation of the dynamics, but would wish to have access to its statistical properties and their generative equations for in-depth analysis...
June 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28573084/desorption-flame-induced-atmospheric-pressure-chemical-ionization-mass-spectrometry-for-rapid-real-world-sample-analysis
#19
Sy-Chyi Cheng, Shih-His Chen, Jentaie Shiea
Flame-induced atmospheric pressure chemical ionization (FAPCI) is a solvent and high voltage-free APCI technique. It uses a flame to produce charged species that reacts with analytes for ionization, and generates intact molecular ions from organic compounds with minimal fragmentation. In this study, desorption FAPCI/MS was developed to rapidly characterize thermally stable organic compounds in liquid, cream, and solid states. Liquid samples were introduced into the ion source through a heated nebulizer, and the analytes formed in the heated nebulizer reacted with charged species in the source...
2017: Mass Spectrometry
https://www.readbyqxmd.com/read/28572778/models-of-disability-in-children-s-pretend-play-measurement-of-cognitive-representations-and-affective-expression-using-the-affect-in-play-scale
#20
Stefano Federici, Fabio Meloni, Antonio Catarinella, Claudia Mazzeschi
Play is a natural mode of children's expression and constitutes a fundamental aspect of their life. Cognitive, affective, and social aspects can be assessed through play, considered as a "window" to observe a child's functioning. According to Russ's model, cognitive and affective components and their reciprocal connections can be assessed through the Affect in Play Scale (APS). The aim of the present study was to investigate children's representations of the three main models of disability (medical, social, and biopsychosocial) and how these models affected cognitive and affective components of children's play...
2017: Frontiers in Psychology
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