keyword
MENU ▼
Read by QxMD icon Read
search

Toys

keyword
https://www.readbyqxmd.com/read/29329426/a-practical-guide-to-estimating-the-heritability-of-pathogen-traits
#1
Venelin Mitov, Tanja Stadler
Pathogen traits, such as the virulence of an infection, can vary significantly between patients. A major challenge is to measure the extent to which genetic differences between infecting strains explain the observed variation of the trait. This is quantified by the trait's broad-sense heritability, H2. A recent discrepancy between estimates of the heritability of HIV-virulence has opened a debate on the estimators' accuracy. Here, we show that the discrepancy originates from model limitations and important lifecycle differences between sexually reproducing organisms and transmittable pathogens...
January 9, 2018: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29325922/the-cost-effectiveness-of-using-paro-a-therapeutic-robotic-seal-to-reduce-agitation-and-medication-use-in-dementia-findings-from-a-cluster-randomized-controlled-trial
#2
Merehau C Mervin, Wendy Moyle, Cindy Jones, Jenny Murfield, Brian Draper, Elizabeth Beattie, David H K Shum, Siobhan O'Dwyer, Lukman Thalib
OBJECTIVES: To examine the within-trial costs and cost-effectiveness of using PARO, compared with a plush toy and usual care, for reducing agitation and medication use in people with dementia in long-term care. DESIGN: An economic evaluation, nested within a cluster-randomized controlled trial. SETTING: Twenty-eight facilities in South-East Queensland, Australia. PARTICIPANTS: A total of 415 residents, all aged 60 years or older, with documented diagnoses of dementia...
January 9, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29325544/prevalence-and-associated-factors-of-wheezing-illnesses-of-children-aged-three-to-five-years-living-in-under-served-settlements-of-the-colombo-municipal-council-in-sri-lanka-a-cross-sectional-study
#3
Ruwanika Seneviratne, Nalika S Gunawardena
BACKGROUND: A rising trend in Sri Lanka for asthma and wheezing illness is observed with higher morbidity in younger children and a paucity of related research. 'Under-served settlements' (USS) of Colombo Municipal Council (CMC) have poor living environments conducive to childhood wheezing. The objective was to describe the prevalence and associated factors of wheezing illnesses of three to five year old children living in low-income settlements in CMC. METHODS: A cross-sectional study was conducted on 460 three to five year old children and their caregivers using cluster sampling among residents of two randomly selected USSs of CMC...
January 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29324240/cognitive-science-in-the-era-of-artificial-intelligence-a-roadmap-for-reverse-engineering-the-infant-language-learner
#4
Emmanuel Dupoux
Spectacular progress in the information processing sciences (machine learning, wearable sensors) promises to revolutionize the study of cognitive development. Here, we analyse the conditions under which 'reverse engineering' language development, i.e., building an effective system that mimics infant's achievements, can contribute to our scientific understanding of early language development. We argue that, on the computational side, it is important to move from toy problems to the full complexity of the learning situation, and take as input as faithful reconstructions of the sensory signals available to infants as possible...
January 8, 2018: Cognition
https://www.readbyqxmd.com/read/29319442/clinical-signs-treatment-and-prognostic-factors-for-dogs-with-histoplasmosis
#5
Allison G Wilson, Kate S KuKanich, Andrew S Hanzlicek, Mark E Payton
OBJECTIVE To determine the clinical manifestations of histoplasmosis in a large sample of dogs, compare outcomes achieved with fluconazole versus itraconazole, and identify variables available at the time of diagnosis with prognostic value. DESIGN Retrospective case series with nested cohort study. ANIMALS 79 dogs with confirmed histoplasmosis evaluated at 2 veterinary teaching hospitals from 1999 through 2015. PROCEDURES Medical records were reviewed and data extracted regarding clinical signs at evaluation, physical examination findings, clinical laboratory values, other diagnostic test results, treatments, and outcomes...
January 15, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29316498/the-relation-between-having-siblings-and-children-s-cheating-and-lie-telling-behaviors
#6
Alison M O'Connor, Angela D Evans
The current study investigated how having at least one child sibling influenced children's dishonest behaviors. Furthermore, for those children with a sibling, we examined whether having a younger or older sibling and the age difference between siblings influenced deceptive acts. Children between 3 and 8 years of age (N = 130) completed the temptation resistance paradigm, where they played a guessing game and were asked not to peek at a toy in the experimenter's absence. Children's peeking behavior was used as a measure of cheating, and children's responses when asked whether they had peeked were used as measures of lie-telling...
January 6, 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29313308/noise-pollution-and-impact-on-children-health
#7
REVIEW
Alok Gupta, Anant Gupta, Khushbu Jain, Sweta Gupta
With rapid urbanization and life style changes, loud noise is omnipresent and has become a part of life. Indoor and outdoor environmental noise pollution have been documented as a serious health hazard with increasing adverse effects on fetus, infants, children, adolescents and adults. Noise induced hearing loss and non-auditory adverse effects due to noise pollution, are being increasingly diagnosed in all age groups including the fetus. Outdated motorized vehicles, machinery, increasing traffic, congested residential areas, crowded educational institutions and workplaces, unregulated commercial and industrial noise have become a source of noise pollution with long-term disability...
January 9, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29307043/plastic-toys-as-a-source-of-exposure-to-bisphenol-a-and-phthalates-at-childcare-facilities
#8
Gangadhar Andaluri, Muruganandham Manickavachagam, Rominder Suri
Infants and toddlers are constantly exposed to toys at childcare facilities. Toys are made of a variety of plastics that often use endocrine-disrupting chemicals such as bisphenol-A (BPA) and phthalates as their building blocks. The goal of this study was to assess the non-dietary exposure of infants and toddlers to BPA and phthalates via leaching. We have successfully developed wipe tests to evaluate the leachability of BPA and phthalates from toys used at several day care facilities in Philadelphia. Our studies have shown an average leaching of 13-280 ng/cm2 of BPA and phthalates...
January 6, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29303052/learning-to-avoid-spiders-fear-predicts-performance-not-competence
#9
Xijia Luo, Eni S Becker, Mike Rinck
We used an immersive virtual environment to examine avoidance learning in spider-fearful participants. In 3 experiments, participants were asked to repeatedly lift one of 3 virtual boxes, under which either a toy car or a spider appeared and then approached the participant. Participants were not told that the probability of encountering a spider differed across boxes. When the difference was large (Exps. 1 and 2), spider-fearfuls learned to avoid spiders by lifting the few-spiders-box more often and the many-spiders-box less often than non-fearful controls did...
January 5, 2018: Cognition & Emotion
https://www.readbyqxmd.com/read/29299588/polyunsaturated-fatty-acid-amides-from-the-zanthoxylum-genus-from-culinary-curiosities-to-probes-for-chemical-biology
#10
REVIEW
Jason J Chruma, Douglas J Cullen, Lydia Bowman, Patrick H Toy
Covering up to February 2017The pericarps of several species from the Zanthoxylum genus, a.k.a. the "prickly ash", have long been used for culinary purposes throughout Asia, most notably in the Sichuan (previously Szechuan) cuisine of Southwestern China, due to the unique tingling and numbing orosensations arising from a collection of polyunsaturated fatty acid amide (alkamide) constituents. The past decade has experienced dramatically increased academic and industrial interest in these pungent Zanthoxylum-derived alkamides, with a concomitant explosion in studies aimed at elucidating the specific biochemical mechanisms behind several medically-relevant biological activities exhibited by the natural products...
January 4, 2018: Natural Product Reports
https://www.readbyqxmd.com/read/29291048/toy-trains-loaded-dice-and-the-origin-of-life-dimerization-on-mineral-surfaces-under-periodic-drive-with-gaussian-inputs
#11
Rowena Ball, John Brindley
In a major extension of previous work, we model the putative hydrothermal rock pore setting for the origin of life on Earth as a series of coupled continuous flow units (the toy train). Perfusing through this train are reactants that set up thermochemical and pH oscillations, and an activated nucleotide that produces monomer and dimer monophosphates. The dynamical equations that model this system are thermally self-consistent. In an innovative step that breaks some new ground, we build stochasticity of the inputs into the model...
November 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29289047/attractor-learning-in-synchronized-chaotic-systems-in-the-presence-of-unresolved-scales
#12
W Wiegerinck, F M Selten
Recently, supermodels consisting of an ensemble of interacting models, synchronizing on a common solution, have been proposed as an alternative to the common non-interactive multi-model ensembles in order to improve climate predictions. The connection terms in the interacting ensemble are to be optimized based on the data. The supermodel approach has been successfully demonstrated in a number of simulation experiments with an assumed ground truth and a set of good, but imperfect models. The supermodels were optimized with respect to their short-term prediction error...
December 2017: Chaos
https://www.readbyqxmd.com/read/29285034/performance-of-preschoolers-mothers-and-senior-dental-students-after-receiving-training-on-fluoride-varnish-administration
#13
Simin Zahra Mohebbi, Samaneh Razeghi, Zahra Chinipardaz, Hamideh Soleimannejad, Mohammad Javad Kharazifard
Objectives: Fluoride varnish application is an effective way to prevent caries in children. We aimed to educate preschool children's mothers on how to apply fluoride varnish and compare their performance with dental students and to assess their self-reported competency six months later. Materials and Methods: Eighty-eight 4-6-year-old children presenting to toy houses of six randomly selected health centers in a non-affluent district of Tehran in 2014 were divided into two groups to receive fluoride varnish by their mothers and students...
July 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29284682/glucocorticoids-induce-differentiation-of-monocytes-towards-macrophages-that-share-functional-and-phenotypical-aspects-with-erythroblastic-island-macrophages
#14
Esther Heideveld, Lea A Hampton-O'Neil, Stephen J Cross, Floris P J van Alphen, Maartje van den Biggelaar, Ashley M Toye, Emile van den Akker
The classical central macrophage found in erythroblastic islands plays an important role in erythroblast differentiation, proliferation and enucleation in the bone marrow. Convenient human in vitro models to facilitate the study of erythroid-macrophage interactions are desired. Recently, we demonstrated that cultured monocytes/macrophages enhance in vitro erythropoiesis by supporting hematopoietic stem cell survival. Here, we describe that these specific macrophages also support erythropoiesis. Human monocytes cultured in serum-free media supplemented with stem cell factor, erythropoietin, lipids and dexamethasone differentiate towards macrophages expressing CD16, CD163, CD169, CD206, CXCR4 and the phagocytic TAM-receptor family...
December 28, 2017: Haematologica
https://www.readbyqxmd.com/read/29284046/irsp53-accumulates-at-the-postsynaptic-density-under-excitatory-conditions
#15
Ayse Dosemeci, Amelia Burch, Hannah Loo, Dana Toy, Jung-Hwa Tao-Cheng
IRSp53 (BAIAP2) is an abundant protein at the postsynaptic density (PSD) that binds to major PSD scaffolds, PSD-95 and Shanks, as well as to F-actin. The distribution of IRSp53 at the PSD in cultured hippocampal neurons was examined under basal and excitatory conditions by immuno-electron microscopy. Under basal conditions, label for IRSp53 is concentrated at the PSD. Upon depolarization by application of a medium containing 90 mM K+, the intensity of IRSp53 label at the PSD increased by 36±7%. Application of NMDA (50 μM) yielded 53±1% increase in the intensity of IRSp53 label at the PSD compared to controls treated with APV, an NMDA antagonist...
2017: PloS One
https://www.readbyqxmd.com/read/29282989/using-a-therapeutic-companion-robot-for-dementia-symptoms-in-long-term-care-reflections-from-a-cluster-rct
#16
Wendy Moyle, Cindy Jones, Jenny Murfield, Lukman Thalib, Elizabeth Beattie, David Shum, Brian Draper
OBJECTIVES: We undertook a cluster-randomised controlled trial exploring the effect of a therapeutic companion robot (PARO) compared to a look-alike plush toy and usual care on dementia symptoms of long-term care residents. Complementing the reported quantitative outcomes , this paper provides critical reflection and commentary on individual participant responses to PARO, observed through video recordings , with a view to informing clinical practice and research. METHOD: A descriptive, qualitative design with five participants selected from the PARO intervention arm of the trial...
December 28, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29280059/team-based-learning-module-for-undergraduate-medical-education-a-module-focused-on-the-human-papilloma-virus-to-increase-willingness-to-vaccinate
#17
Rachel Wiley, Zeena Shelal, Carolyn Bernard, Diana Urbauer, Eugene Toy, Lois Ramondetta
Human papilloma virus (HPV) vaccination rates lag behind other vaccines, primarily because of weak provider recommendations, and are associated with nearly 30,000 new cancer diagnoses a year. Educating medical students about HPV using active, team-centered learning may increase assimilation of information and may increase vaccination rates. A team-based learning (TBL) module focused on HPV for first-year medical students about HPV will better increase knowledge and likeliness to vaccinate than traditional education methods...
December 26, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29279683/evaluation-of-child-preference-for-dentist-attire-and-usage-of-camouflage-syringe-in-reduction-of-anxiety
#18
Prashant Babaji, Pavni P Chauhan, Vikram Rathod, Swapnil Mhatre, Uttam Paul, Guneet Guram
Objectives: The aim of this study is to evaluate the child preference for dentist attire and camouflage versus conventional syringe in reduction of anxiety. Materials and Methods: A total of 600 children aged 6-14 years were made to look at a set of six photos of an individual dressed with different colored apron of pink, green, blue, white colors, formal dress, and cartoon character along with conventional syringe and camouflage syringe with a toy-like appearance to permit injection of local anesthesia...
October 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/29274660/mirror-mirror-on-the-wall-increasing-young-children-s-honesty-through-inducing-self-awareness
#19
Jasmine Bender, Alison M O'Connor, Angela D Evans
Previous studies have shown that in older children, promising to tell the truth increases truth-telling rates; however, in preschool-aged children, this has not been found to be effective. The current study compared promising with a novel technique of increasing children's self-awareness (by asking children to look at themselves in a mirror). It was predicted that inducing self-awareness would encourage children's honesty given that self-awareness increases adherence to social and moral norms. Children aged 3 or 4 years (N = 135) completed a modified temptation resistance paradigm where they were asked to not peek at a toy in the absence of an experimenter...
December 20, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29273663/meta-ethnography-to-understand-healthcare-professionals-experience-of-treating-adults-with-chronic-non-malignant-pain
#20
Francine Toye, Kate Seers, Karen L Barker
OBJECTIVES: We aimed to explore healthcare professionals' experience of treating chronic non-malignant pain by conducting a qualitative evidence synthesis. Understanding this experience from the perspective of healthcare professionals will contribute to improvements in the provision of care. DESIGN: Qualitative evidence synthesis using meta-ethnography. We searched five electronic bibliographic databases from inception to November 2016. We included studies that explore healthcare professionals' experience of treating adults with chronic non-malignant pain...
December 21, 2017: BMJ Open
keyword
keyword
103570
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"