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https://www.readbyqxmd.com/read/28823088/electrical-signals-triggered-controllable-formation-of-calcium-alginate-film-for-wound-treatment
#1
Xiaoli Liu, Huan Liu, Xue Qu, Miao Lei, Chuchu Zhang, Hua Hong, Gregory F Payne, Changsheng Liu
Wound dressings play important roles in the management of wounds, and calcium cross-linked alginate (Ca(2+)-Alg) is a commonly used hydrogel that is adapted for wound treatment. However, conventional methods for fabricating Ca(2+)-Alg hydrogels can be tedious and difficult to control because of the rapid Ca(2+)-induced gelation of alginate. In this study, An electrodeposition method was used to rapidly and controllably fabricate Ca(2+)-Alg films for wound treatment. Several measures of film growth (e.g., thickness and mass) are shown to linearly correlate to the imposed charge transfer at the electrode...
August 19, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28822875/a-consortium-driven-framework-to-guide-the-implementation-of-ich-m7-option-4-control-strategies
#2
Chris Barber, Vincent Antonucci, Jens-Christoph Baumann, Roland Brown, Elizabeth Covey-Crump, David Elder, Eric Elliott, Jared W Fennell, Fabrice Gallou, Nathan D Ide, Guido Jordine, Jeffrey M Kallemeyn, Dirk Lauwers, Adam R Looker, Lucie E Lovelle, Mark McLaughlin, Robert Molzahn, Martin Ott, Didier Schils, Rolf Schulte Oestrich, Neil Stevenson, Pere Talavera, Andrew Teasdale, Michael W Urquhart, David L Varie, Dennie Welch
The ICH M7 Option 4 control of (potentially) mutagenic impurities is based on the use of scientific principles in lieu of routine analytical testing. This approach can reduce the burden of analytical testing without compromising patient safety, provided a scientifically rigorous approach is taken which is backed up by sufficient theoretical and/or analytical data. This paper introduces a consortium-led initiative and offers a proposal on the supporting evidence that could be presented in regulatory submissions...
August 16, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28822860/phloretin-loaded-fast-dissolving-nanofibers-for-the-locoregional-therapy-of-oral-squamous-cell-carcinoma
#3
Suyeong Nam, Song Yi Lee, Hyun-Jong Cho
Fast dissolving nanofiber (NF) composed of poly(vinyl alcohol) (PVA) and d-α-tocopheryl polyethylene glycol succinate (TPGS) was developed for locoregional delivery of phloretin to oral cancers. PVA/TPGS/phloretin NF with 321nm mean diameter and >90% drug entrapment efficiency was fabricated by an electrospinning method. Transformation of drug from crystalline to amorphous state was identified by solid-state studies. NF structure was changed to nanoparticles after its dispersing in the aqueous medium. PVA/TPGS/phloretin NF exhibited fast wetting property and smaller hydrodynamic size of dispersion, compared with PVA/phloretin NF...
August 12, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28822536/impression-evaluation-and-laboratory-use-for-single-unit-crowns-findings-from-the-national-dental-practice-based-research-network
#4
Michael S McCracken, Mark S Litaker, Ashley J George, Scott Durand, Sepideh Malekpour, Don G Marshall, Cyril Meyerowitz, Lauren Carter, Valeria V Gordan, Gregg H Gilbert
BACKGROUND: Objectives were to determine the likelihood that a clinician accepts an impression for a single-unit crown and document crown remake rates. METHODS: The authors developed a questionnaire that asked dentists about techniques used to fabricate single-unit crowns. The authors showed dentists photographs of 4 impressions and asked them to accept or reject each impression. The authors correlated answers with dentist and practice characteristics. Other questions pertained to laboratory use and crown remake rates...
August 16, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28822482/towards-an-integrated-species-and-habitat-management-of-crop-pollination
#5
REVIEW
Lucas A Garibaldi, Fabrice Requier, Orianne Rollin, Georg Ks Andersson
Pollination deficits are widespread in current agriculture, so improving management for crop pollination is critical. Here we review the two most common management approaches to enhance crop pollination, species and habitat management, by providing referenced lists of successful examples. We pinpoint that these approaches have been studied in isolation from each other, with little discussion on potential synergies and trade-offs between them. The potential costs of species management (e.g., loss of biodiversity due to biological invasion), as well as the potential benefits to managed pollinator species from habitat restoration, are rarely quantified...
June 2017: Current Opinion in Insect Science
https://www.readbyqxmd.com/read/28822330/effect-of-the-microstructure-on-the-propagation-velocity-of-ultrasound-in-magnetic-powders
#6
Francisco Ruiz Botello, Miguel A S Quintanilla, Antonio Castellanos, Elena F Grekova, Vincent Tournat
We analyze experimentally and theoretically the sound propagation velocity of P-waves in granular media made of micrometer-size magnetite particles under an external magnetic field. The sound velocity is measured in a coherent (long-wavelength) regime of propagation after a controlled sample preparation consisting of a fluidization and the application of a magnetic field. Several different procedures are applied and result in different but reproducible particle arrangements and preferential contact orientations affecting the measured sound velocity...
August 1, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28822293/synthesis-of-hexagonal-mesoporous-mgal-ldh-nanoplatelets-adsorbent-for-the-effective-adsorption-of-brilliant-yellow
#7
Reza Pourfaraj, Seyed Jamilaldin Fatemi, Sayed Yahya Kazemi, Pourya Biparva
Hexagonal mesoporous MgAl layered double hydroxide (LDH) was synthesized through a simple hydrothermal method and was employed without calcination as adsorbent in the removal of the direct anionic azo dye, Brilliant Yellow (BY). The adsorbent was characterized by XRD, FT-IR, SEM and BET surface area. Hexagonal platelets of MgAl LDH were fabricated with nanometric building blocks. Batch experiments were carried out for study effects of contact time, amount of adsorbent, solution pH and solution temperature on the removal efficiency of BY...
July 29, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28821881/high-operating-temperature-in-v-based-superconducting-quantum-interference-proximity-transistors
#8
Nadia Ligato, Giampiero Marchegiani, Pauli Virtanen, Elia Strambini, Francesco Giazotto
Here we report the fabrication and characterization of fully superconducting quantum interference proximity transistors (SQUIPTs) based on the implementation of vanadium (V) in the superconducting loop. At low temperature, the devices show high flux-to-voltage (up to 0.52 mV/Φ0) and flux-to-current (above 12 nA/Φ0) transfer functions, with the best estimated flux sensitivity ~ 2.6 μΦ0/(Hz)(1/2) reached under fixed voltage bias, where Φ0 is the flux quantum. The interferometers operate up to T bath  [Formula: see text] 2 K, with an improvement of 70% of the maximal operating temperature with respect to early SQUIPTs design...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821862/water-soluble-epitaxial-nacl-thin-film-for-fabrication-of-flexible-devices
#9
Dong Kyu Lee, Sungjoo Kim, Sein Oh, Jae-Young Choi, Jong-Lam Lee, Hak Ki Yu
We studied growth mechanisms of water-soluble NaCl thin films on single crystal substrates. Epitaxial growth of NaCl(100) on Si(100) and domain-matched growth of NaCl(111) on c-sapphire were obtained at thicknesses below 100 nm even at room temperature from low lattice mismatches in both cases. NaCl thin film, which demonstrates high solubility selectivity for water, was successfully applied as a water-soluble sacrificial layer for fabrication of several functional materials, such as WO3 nano-helix and Sn doped In2O3 nano-branches...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821851/mass-production-of-bulk-artificial-nacre-with-excellent-mechanical-properties
#10
Huai-Ling Gao, Si-Ming Chen, Li-Bo Mao, Zhao-Qiang Song, Hong-Bin Yao, Helmut Cölfen, Xi-Sheng Luo, Fu Zhang, Zhao Pan, Yu-Feng Meng, Yong Ni, Shu-Hong Yu
Various methods have been exploited to replicate nacre features into artificial structural materials with impressive structural and mechanical similarity. However, it is still very challenging to produce nacre-mimetics in three-dimensional bulk form, especially for further scale-up. Herein, we demonstrate that large-sized, three-dimensional bulk artificial nacre with comprehensive mimicry of the hierarchical structures and the toughening mechanisms of natural nacre can be facilely fabricated via a bottom-up assembly process based on laminating pre-fabricated two-dimensional nacre-mimetic films...
August 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28821849/the-preparation-and-application-of-a-graphene-based-hybrid-flame-retardant-containing-a-long-chain-phosphaphenanthrene
#11
Wenhua Chen, Yuansen Liu, Pengju Liu, Changan Xu, Yuan Liu, Qi Wang
A novel hybrid flame retardant combining graphene oxide (GO) with long-chain phosphaphenanthrene was fabricated via surface grafting reaction. Taking advantageous of the double barrier effects, including the physical shield contributed by graphene nanoplates during the initial stage and the chemical char contributed by phosphaphenanthrene during the later stage, greatly decreased the release rate of decomposed volatiles from the resin, as well as minimized the release of oxygen and combustion heat. Hence, such hybrid flame retardant can overcome the shortcomings of early acid catalyzed degradation effects caused by conventional flame retardants containing phosphorus...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821794/a-twice-electrochemical-etching-method-to-fabricate-superhydrophobic-superhydrophilic-patterns-for-biomimetic-fog-harvest
#12
Xiaolong Yang, Jinlong Song, Junkai Liu, Xin Liu, Zhuji Jin
Superhydrophobic-superhydrophilic patterned surfaces have attracted more and more attention due to their great potential applications in the fog harvest process. In this work, we developed a simple and universal electrochemical-etching method to fabricate the superhydrophobic-superhydrophilic patterned surface on metal superhydrophobic substrates. The anti-electrochemical corrosion property of superhydrophobic substrates and the dependence of electrochemical etching potential on the wettability of the fabricated dimples were investigated on Al samples...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821779/a-clean-and-facile-synthesis-strategy-of-mos2-nanosheets-grown-on-multi-wall-cnts-for-enhanced-hydrogen-evolution-reaction-performance
#13
Jiamu Cao, Jing Zhou, Yufeng Zhang, Xiaowei Liu
Unique hybrid nanostructure, which consists of multi-wall carbon nanotube (MWCNT) stems and MoS2 nanosheet (NS) leaves, are prepared by a hydrothermal method. The fabricated material can be potentially used as an electrocatalyst for the hydrogen evolution reaction (HER). To our knowledge, as the reaction medium, water is firstly utilized to the synthesis of the 1T phase MoS2 NSs which uniformly grow on the carbon-based materials. As a result, a nanohybrid catalyst with excellent HER electrocatalytic properties, which included an onset potential of as low as 50 mV, a Tafel slope of 43 mV dec(-1), and remarkable cycling stability, is produced...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821773/a-patterned-single-layer-graphene-resistance-temperature-sensor
#14
Benyamin Davaji, Hak Dong Cho, Mohamadali Malakoutian, Jong-Kwon Lee, Gennady Panin, Tae Won Kang, Chung Hoon Lee
Micro-fabricated single-layer graphenes (SLGs) on a silicon dioxide (SiO2)/Si substrate, a silicon nitride (SiN) membrane, and a suspended architecture are presented for their use as temperature sensors. These graphene temperature sensors act as resistance temperature detectors, showing a quadratic dependence of resistance on the temperature in a range between 283 K and 303 K. The observed resistance change of the graphene temperature sensors are explained by the temperature dependent electron mobility relationship (~T(-4)) and electron-phonon scattering...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821718/high-energy-storage-density-over-a-broad-temperature-range-in-sodium-bismuth-titanate-based-lead-free-ceramics
#15
Haibo Yang, Fei Yan, Ying Lin, Tong Wang, Fen Wang
A series of (1-x)Bi0.48La0.02Na0.48Li0.02Ti0.98Zr0.02O3-xNa0.73Bi0.09NbO3 ((1-x)LLBNTZ-xNBN) (x = 0-0.14) ceramics were designed and fabricated using the conventional solid-state sintering method. The phase structure, microstructure, dielectric, ferroelectric and energy storage properties of the ceramics were systematically investigated. The results indicate that the addition of Na0.73Bi0.09NbO3 (NBN) could decrease the remnant polarization (P r ) and improve the temperature stability of dielectric constant obviously...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821321/educational-level-and-family-structure-influence-the-dietary-changes-after-the-diagnosis-of-type-2-diabetes-evidence-from-the-e3n-study
#16
Francesca Romana Mancini, Aurelie Affret, Courtney Dow, Beverley Balkau, Hélène Bihan, Françoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Fabrice Bonnet, Guy Fagherazzi
Type 2 diabetes (T2D) has no cure but can be controlled by medication, diet, and lifestyle changes. It has been suggested that diabetes dietary self-management is more difficult for people with socioeconomic difficulties. The objective of our study was to test the hypothesis that socioeconomic factors impact the change of diet after T2D diagnosis. The 57 304 French women included in the present study answered food frequency questionnaires in 1993 and 2005 and questionnaires on socioeconomic factors, and were free from T2D in 1993...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28821170/esc-joint-working-groups-on-cardiovascular-surgery-and-the-cellular-biology-of-the-heart-position-paper-perioperative-myocardial-injury-and-infarction-in-patients-undergoing-coronary-artery-bypass-graft-surgery
#17
Matthias Thielmann, Vikram Sharma, Nawwar Al-Attar, Heerajnarain Bulluck, Gianluigi Bisleri, Jeroen Jh Bunge, Martin Czerny, Péter Ferdinandy, Ulrich H Frey, Gerd Heusch, Johannes Holfeld, Petra Kleinbongard, Gudrun Kunst, Irene Lang, Salvatore Lentini, Rosalinda Madonna, Patrick Meybohm, Claudio Muneretto, Jean-Francois Obadia, Cinzia Perrino, Fabrice Prunier, Joost P G Sluijter, Linda W Van Laake, Miguel Sousa-Uva, Derek J Hausenloy
No abstract text is available yet for this article.
August 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28821132/the-effect-of-%C3%AE-cyclodextrin-on-poly-pseudo-rotaxane-nanoparticles-self-assembled-by-protoporphyrin-modified-poly-ethylene-glycol-for-anticancer-drug-delivery
#18
Taotao Xu, Junhua Li, Jun Cao, Wenxia Gao, Li Li, Bin He
Poly(pseudo)rotaxane (PPR) nanoparticles was facilely prepared using poly(ethylene glycol) (PEG) modified with protoporphyrin (PpIX) and α-cyclodextrin (α-CD) via host-guest interaction, the effect of α-CD number on the nanoparticle properties was investigated. The PEG with protoporphyrin (PEG-PpIX) end capping was synthesized via coupling reaction and the poly(pseudo)rotaxane nanoparticles with different amount of α-CD were fabricated by host-guest interaction between mPEG-PpIX and α-CDs. The final product was characterized by nuclear magnetic spectrum ((1)H NMR), X-ray diffraction (XRD), atomic force microscope (AFM) and dynamic light scattering (DLS)...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821128/biomimetic-composite-scaffolds-based-on-surface-modification-of-polydopamine-on-electrospun-poly-lactic-acid-cellulose-nanofibrils
#19
Zhangqiang Yang, Junhui Si, Zhixiang Cui, Jianhua Ye, Xiaofeng Wang, Qianting Wang, Kaiping Peng, Wenzhe Chen, Shia-Chung Chen
An appropriate surface chemical property is crucial in tissue engineering scaffolds, which promotes cell attachment and proliferation. A biomimetic composite scaffold with a polydopamine (PDA) coating layer on electrospun poly(lactic acid) (PLA)/cellulose nanofibrils (CNF) composite nanofiber was developed in this study. PLA/CNF composite nanofibers were fabricated and then coated via treatment with a dopamine solution. The PDA coating layer was successfully formed on the surface of the PLA/CNF composite nanofiber by using a simple, environment-friendly, and effective procedure...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821119/tailoring-of-temperature-and-ph-responsive-cotton-fabric-with-antimicrobial-activity-effect-of-the-concentration-of-a-bio-barrier-forming-agent
#20
Danaja Štular, Ivan Jerman, Barbara Simončič, Brigita Tomšič
A stimuli-responsive cotton fabric was designed using temperature and pH-responsive poly-N-isopropylacrylamide (poly-NiPAAm) and chitosan (PNCS) microgel as a carrier of antimicrobially active 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride (Si-QAC), which forms a bio-barrier on the fibre surface. The influence of Si-QAC on the moisture management and thermoregulation abilities of the PNCS microgel was investigated. Using a pad-dry cure method, Si-QAC was applied to a 100% cotton fabric model in concentrations ranging from 0...
October 15, 2017: Carbohydrate Polymers
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