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Claúdia Mendes da Silva, Regina de Souza Alves, Tâmyssa Simões Dos Santos, Gabriela Rodrigues Bragagnollo, Clodis Maria Tavares, Amuzza Aylla Pereira Dos Santos
OBJECTIVE: To learn the epidemiological characteristics of HIV infection in pregnant women. METHOD: Descriptive study with quantitative approach. The study population was composed of pregnant women with HIV/AIDS residing in the state of Alagoas. Data were organized into variables and analyzed according to the measures of dispersion parameter relevant to the arithmetic mean and standard deviation (X ± S). RESULTS: Between 2007 and 2015, 773 cases of HIV/AIDS were recorded in pregnant women in Alagoas...
2018: Revista Brasileira de Enfermagem
Alexandre de Matos Soeiro, Victor Arrais Araújo, Júlia Pitombo Vella, Aline Siqueira Bossa, Bruno Biselli, Tatiana de Carvalho Andreucci Torres Leal, Maria Carolina Feres de Almeida Soeiro, Carlos V Serrano, Christian Mueller, Mucio Tavares de Oliveira Junior
BACKGROUND: Some small studies have related higher levels of thyrotropin (TSH) to potentially worse prognosis in acute coronary syndromes. However, this relationship remains uncertain. OBJECTIVE: To analyze the outcomes of patients with acute coronary syndromes in relation to the value of TSH at admission. METHODS: Observational and retrospective study with 505 patients (446 in group I [TSH ≤ 4 mIU/L] and 59 in group II [TSH > 4 mIU/L]) with acute coronary syndromes between May 2010 and May 2014...
February 2018: Arquivos Brasileiros de Cardiologia
Danielle Menosi Gualandro, Nancy Bellei, Mucio Tavares de Oliveira, Sérgio Montenegro
No abstract text is available yet for this article.
January 2018: Revista da Associação Médica Brasileira
Fernanda Dos Santos Cunha, Natalino da Costa Sousa, Rudã Fernandes Brandão Santos, Juliana Oliveira Meneses, Márcia Valéria Silva do Couto, Fabrício Tavares Cunha de Almeida, José Guedes de Sena Filho, Paulo César Falanghe Carneiro, Alexandre Nizio Maria, Rodrigo Yudi Fujimoto
Deltamethrin is one of the most commonly used pyrethroids in the world, and it has a high toxic potential, mainly on aquatic organism. Thus, the purpose of this study was to evaluate LC50 values of deltamethrin on tambaqui (Colossoma macropomum) fingerlings and to investigate genotoxic effects and histopathological responses. Fish were exposed to different concentrations of deltamethrin (0, 6.16 × 10-3 ; 6.44 × 10-2 ; 1.34 × 10-1 , and 1.93 × 10-1  mg L-1 ) for 96 h. In addition, a genotoxicity analysis was carried out on peripheral blood erythrocytes and histopathological changes were classified by the severity degree of damage and organ functioning...
March 20, 2018: Environmental Science and Pollution Research International
Amy Reilein, David Melamed, Simon Tavaré, Daniel Kalderon
Cancer-initiating gatekeeper mutations that arise in stem cells would be especially potent if they stabilize and expand an affected stem cell lineage. It is therefore important to understand how different stem cell organization strategies promote or prevent variant stem cell amplification in response to different types of mutation, including those that activate proliferation. Stem cell numbers can be maintained constant while producing differentiated products through individually asymmetrical division outcomes or by population asymmetry strategies in which individual stem cell lineages necessarily compete for niche space...
March 19, 2018: Proceedings of the National Academy of Sciences of the United States of America
João Castelhano, Paula Tavares, Susana Mouga, Guiomar Oliveira, Miguel Castelo-Branco
OBJECTIVE: Electroencephalographic biomarkers have been widely investigated in autism, in the search for diagnostic, prognostic and therapeutic outcome measures. Here we took advantage of the information available in temporal oscillatory patterns evoked by simple perceptual decisions to investigate whether stimulus dependent oscillatory signatures can be used as potential biomarkers in autism spectrum disorder (ASD). METHODS: We studied an extensive set of stimuli (9 categories of faces) and performed data driven classification (Support vector machine, SVM) of ASD vs...
February 20, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Lucas G Cespedes, Rafael A T P S Nahat, Thatiane T Mendonça, Rafaela R Tavares, Edmar R Oliveira-Filho, Luiziana F Silva, Marilda K Taciro, Rubén J Sánchez, José G C Gomez
Pseudomonas sp. PHA- was used as host for PHA biosynthesis genes from Aeromonas sp. to produce 3HB-co-3HAMCL from glucose with no supply of co-substrates. A non-naturally-occurring PHA composed mainly of 3HB, 3HHx and 3HD (3HO, 3HDdΔ5 and 3HDd monomers were detected in smaller amounts) was obtained. The polymer was extracted using two different solvents (acetone and chloroform) and subject to the following characterization tests: FTIR, DSC, TGA and GPC. The latter suggests a block copolymer since a single elution narrow peak was observed for each sample...
March 13, 2018: International Journal of Biological Macromolecules
Lígia Renata Rodrigues Tavares, Daniela Baptista-de-Souza, Azair Canto-de-Souza
It is well-known that the exposure of rodents to threatening environments [e.g., the open arm of the elevated-plus maze (EPM)] elicits pain inhibition. Systemic and/or intracerebral [e.g., periaqueductal gray matter, amygdala) injections of antiaversive drugs [e.g., serotonin (5-HT) ligands, selective serotonin reuptake inhibitors (SSRIs)] have been used to change EPM-open arm confinement induced antinociception (OAA). Here, we investigated (i) the role of the 5-HT1A and 5-HT2C receptors located in the amygdaloid complex on OAA as well as (ii) the effects of systemic pretreatment with fluoxetine (an SSRI) on the effects of intra-amygdala injections of 8-OH-DPAT (a 5-HT1A agonist) or MK-212 (a 5-HT2C agonist) on nociception in mice confined to the open arm or enclosed arm of the EPM...
March 13, 2018: Neuropharmacology
William Tavares
No abstract text is available yet for this article.
March 2018: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
Gisela Eugénio, Joao Tavares, Joana Fonseca Ferreira, Armando Malcata
We report a case of a 46-year-old woman with a history of autoimmune atrophic gastritis and recurrent erythema nodosum (EN). Laboratory results showed iron-deficiency anaemia, positive antiparietal cell antibodies and marginal deficiency of vitamin B12. Although EN was refractory to general measures (rest and non-steroidal anti-inflammatory drugs) and corticosteroid therapy, it was successfully treated with vitamin B12 supplementation.
March 15, 2018: BMJ Case Reports
Céline Ronin, David Mendes Costa, Joana Tavares, Joana Faria, Fabrice Ciesielski, Paola Ciapetti, Terry K Smith, Jane MacDougall, Anabela Cordeiro-da-Silva, Iain K Pemberton
The de novo crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1 (LiSir2rp1) has been solved at 1.99Å in complex with an acetyl-lysine peptide substrate. The structure is broadly commensurate with Hst2/SIRT2 proteins of yeast and human origin, reproducing many of the structural features common to these sirtuin deacetylases, including the characteristic small zinc-binding domain, and the larger Rossmann-fold domain involved in NAD+-binding interactions. The two domains are linked via a cofactor binding loop ordered in open conformation...
2018: PloS One
Elie Fiogbé, Rafaela Ferreira, Márcio Antônio Gonçalves Sindorf, Silvia Aparecida Tavares, Keiti Passoni de Souza, Marcelo de Castro Cesar, Charles Ricardo Lopes, Marlene Aparecida Moreno
BACKGROUND AND PURPOSE: It is important to assess the effectiveness and efficiency of water-based training programs in order to prescribe it as an alternative in cardiac rehabilitation for patients who have coronary artery disease (CAD). In these patients, autonomic dysfunction is an important physiological change strongly associated with adverse outcomes, morbidity, and mortality. Given that the beneficial effects of physical training in CAD patients have been traditionally evidenced with programs involving land-based aerobic exercises, this study aims to evaluate the effects of water aerobic exercise training (WAET) on the autonomic modulation of heart rate (HR) and body composition, in the rehabilitation of CAD patients...
March 14, 2018: Physiotherapy Research International: the Journal for Researchers and Clinicians in Physical Therapy
Luís Belo, Isa Serrano, Eva Cunha, Carla Carneiro, Luis Tavares, L Miguel Carreira, Manuela Oliveira
BACKGROUND: Most of surgical site infections (SSI) are caused by commensal and pathogenic agents from the patient's microbiota, which may include antibiotic resistant strains. Pre-surgical asepsis of the skin is one of the preventive measures performed to reduce SSI incidence and also antibiotic resistance dissemination. However, in veterinary medicine there is no agreement on which biocide is the most effective. The aim of this study was to evaluate the effectiveness of two pre-surgical skin asepsis protocols in dogs...
March 14, 2018: BMC Veterinary Research
Rafael Tavares Silveira Silva, Richardson Augusto Rosendo da Silva, Iellen Dantas Campos Verdes Rodrigues, Vinicius Lino de Souza Neto, Bárbara Coeli Oliveira da Silva, Francisca Marta de Lima Costa Souza
OBJECTIVE: to identify the coping strategies of people living with aids to face the disease and analyze them according to sociodemographic, clinical and lifestyle variables. METHOD: this is a cross-sectional quantitative study. The sample consisted of 331 people living with aids treated at an outpatient clinic at a referral hospital for treatment of aids. The Coping Strategies Inventory was used to collect the data. RESULTS: emotion-focused coping modes were more frequently mentioned...
March 8, 2018: Revista Latino-americana de Enfermagem
Darlene Mara Dos Santos Tavares, Alisson Fernandes Bolina, Flavia Aparecida Dias, Pollyana Cristina Dos Santos Ferreira, Nilce Maria de Freitas Santos
This study aimed to verify the association of overweight with functional disability, self-reported morbidities and quality of life (QoL) among rural elderly dwellers. This is a domestic and cross-sectional survey conducted in the rural region of a municipality of Southeast Brazil. Three hundred seventy non-overweight elderly people and 192 overweight elderly people were evaluated with the following tools: semi-structured; Katz and Lawton and scales; World Health Organization Quality of Life - BREF and World Health Organization Quality of Life Assessment for Older Adults...
March 2018: Ciência & Saúde Coletiva
Márcia Aparecida Gonçalves, Bruna Estima Leal, Liseane Gonçalves Lisboa, Michelle Gonçalves de Souza Tavares, Wellington Pereira Yamaguti, Elaine Paulin
OBJECTIVE: To compare diaphragmatic mobility, lung function, and respiratory muscle strength between COPD patients with and without thoracic hyperkyphosis; to determine the relationship of thoracic kyphosis angle with diaphragmatic mobility, lung function, and respiratory muscle strength in COPD patients; and to compare diaphragmatic mobility and thoracic kyphosis between male and female patients with COPD. METHODS: Participants underwent anthropometry, spirometry, thoracic kyphosis measurement, and evaluation of diaphragmatic mobility...
January 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Alexandre de Matos Soeiro, Danielle Menosi Gualandro, Aline Siqueira Bossa, Cindel Nogueira Zullino, Bruno Biselli, Maria Carolina Feres de Almeida Soeiro, Tatiana de Carvalho Andreucci Torres Leal, Carlos Vicente Serrano, Mucio Tavares de Oliveira Junior
INTRODUCTION: Despite having higher sensitivity as compared to conventional troponins, sensitive troponins have lower specificity, mainly in patients with renal failure. OBJECTIVE: Study aimed at assessing the sensitive troponin I levels in patients with chest pain, and relating them to the existence of significant coronary lesions. METHODS: Retrospective, single-center, observational. This study included 991 patients divided into two groups: with (N = 681) and without (N = 310) significant coronary lesion...
January 2018: Arquivos Brasileiros de Cardiologia
Juliano Novaes Cardoso, Carlos Henrique Del Carlo, Mucio Tavares de Oliveira Junior, Marcelo Eidi Ochiai, Roberto Kalil Filho, Antônio Carlos Pereira Barretto
BACKGROUND: Heart failure (HF) is a syndrome, whose advanced forms have a poor prognosis, which is aggravated by the presence of comorbidities. OBJECTIVE: We assessed the impact of infection in patients with decompensated HF admitted to a tertiary university-affiliated hospital in the city of São Paulo. METHODS: This study assessed 260 patients consecutively admitted to our unit because of decompensated HF. The presence of infection and other morbidities was assessed, as were in-hospital mortality and outcome after discharge...
March 12, 2018: Arquivos Brasileiros de Cardiologia
Lívia Jacovassi Tavares, Marlise Inêz Klein, Beatriz Helena Dias Panariello, Erica Dorigatti de Avila, Ana Cláudia Pavarina
Purpose: The goal of this study was to develop and validate a standardized in vitro pathogenic biofilm attached onto saliva-coated surfaces. Methods: Fusobacterium nucleatum (F. nucleatum) and Porphyromonas gingivalis (P. gingivalis) strains were grown under anaerobic conditions as single species and in dual-species cultures. Initially, the bacterial biomass was evaluated at 24 and 48 hours to determine the optimal timing for the adhesion phase onto saliva-coated polystyrene surfaces...
February 2018: Journal of Periodontal & Implant Science
Visesato Mor, Antonella Rella, Amir M Farnoud, Ashutosh Singh, Mansa Munshi, Arielle Bryan, Shamoon Naseem, James B Konopka, Iwao Ojima, Erika Bullesbach, Alan Ashbaugh, Michael J Linke, Melanie Cushion, Margaret Collins, Hari Krishna Ananthula, Larry Sallans, Pankaj B Desai, Nathan P Wiederhold, Annette W Fothergill, William R Kirkpatrick, Thomas Patterson, Lai Hong Wong, Sunita Sinha, Guri Giaever, Corey Nislow, Patrick Flaherty, Xuewen Pan, Gabriele Vargas Cesar, Patricia de Melo Tavares, Susana Frases, Kildare Miranda, Marcio L Rodrigues, Chiara Luberto, Leonardo Nimrichter, Maurizio Del Poeta
No abstract text is available yet for this article.
March 13, 2018: MBio
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