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https://www.readbyqxmd.com/read/29765484/successful-embolization-of-a-enterocutaneous-fistula-tract-with-onyx-34-following-low-anterior-resection-for-rectal-cancer
#1
Hamza Rahimi, Anthony C Venbrux, Vincent Obias
Enterocutaneous fistulas (ECFs) can be one of the complications found after surgical intervention for rectal cancer. Interventional modalities consisting of surgical, endoscopic, and radiological methods are often implemented to treat postoperative symptomatic complications. We present the case of 61-year-old Caucasian man who presented to us with a recent diagnosis of rectal cancer that had invaded the levators as well as anteriorly into the prostate, and who underwent low anterior resection with a diverting loop ileostomy...
June 2018: Radiology case reports
https://www.readbyqxmd.com/read/29742861/clinical-etiology-of-hypermetabolic-pelvic-lesions-in-postoperative-positron-emission-tomography-computed-tomography-for-patients-with-rectal-and-sigmoid-cancer
#2
Yun Hee Kang, Eunji Han, Geon Park
PURPOSE: The purpose of this study was to present various clinical etiologies of hypermetabolic pelvic lesions on postoperative positron emission tomography/computed tomography (PET/CT) images for patients with rectal and sigmoid cancer. METHODS: Postoperative PET/CT images for patients with rectal and sigmoid cancer were retrospectively reviewed to identify hypermetabolic pelvic lesions. Positive findings were detected in 70 PET/CT images from 45 patients; 2 patients who were lost to follow-up were excluded...
April 2018: Annals of Coloproctology
https://www.readbyqxmd.com/read/29722725/antegrade-enema-after-total-mesorectal-excision-for-rectal-cancer-the-last-chance-to-avoid-definitive-colostomy-for-refractory-low-anterior-resection-syndrome-and-fecal-incontinence
#3
Romain Didailler, Quentin Denost, Paula Loughlin, Edouard Chabrun, Julie Ricard, Flor Picard, Frank Zerbib, Eric Rullier
BACKGROUND: Total mesorectal excision and preoperative radiotherapy in mid and low rectal cancer allow us to achieve very good oncological results. However, major and refractory low anterior resection syndrome and fecal incontinence alter the quality of life of patients with a long expected life span. OBJECTIVE: We assessed the functional results of patients treated by antegrade enema for refractory low anterior resection syndrome and fecal incontinence after total mesorectal excision...
June 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29682712/-incidence-and-risk-factors-for-anastomotic-leakage-after-anterior-resection-for-rectal-cancer
#4
Jun Li, Yongbo An, Guocong Wu, Xiaomu Zhao, Yingchi Yang, Jin Wang, Lan Jin, Hongwei Wu, Na Zeng, Fuxiao Xie, Jie Dong, Anlong Yuan, Wuqing Sun, Ruiqing Zhou, Hongwei Yao, Zhongtao Zhang
OBJECTIVE: To assess the incidence and independent risk factors for clinical anastomotic leakage (AL) in patients undergoing anterior resection(AR) or low anterior resection, (LAR) for rectal cancer. METHODS: This was a retrospective case-control study of 550 patients with rectal cancer who underwent AR or LAR from April 2007 to March 2017 in Beijing Friendship Hospital, Capital Medical University. The relationship between the incidence of AL and clinicopathological manifestations was analyzed by Chi-squared test and Fisher exact test, and the independent risk factors of AL were analyzed using logistic regression analysis...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29682704/-anastomotic-leakage-after-rectal-cancer-surgery-classification-and-management
#5
Pan Chi, Shenghui Huang
Many studies have focused on the identification of risk factors and prevention of anastomotic leakage following rectal cancer surgery. However, there is little knowledge regarding classification and management of anastomotic leakage in clinic. Herein, we reviewed and summarized the classification and management of anastomotic leakage after rectal cancer surgery. The relevant treatments of anastomotic leakage should be chosen based on patient's manifestation, including general and local reactions, anatomical location, and nature of the leakage (contained or free, controlled or uncontrolled leakage)...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29650830/-curative-resection-for-unresectable-locally-advanced-colorectal-cancer-following-intensive-chemotherapy-plus-molecular-targeted-agent-report-of-three-cases
#6
Yuto Hozaka, Shinichiro Mori, Yoshiaki Kita, Kenji Baba, Takaaki Arigami, Yoshikazu Uenosono, Yasuto Uchikado, Yuko Mataki, Kosei Maemura, Shoji Natsugoe
Intensive chemotherapy plus molecular targeted agent improve overall survival for patients with unresectable colorectal cancer.We performed laparoscopic surgery following intensive chemotherapy of mFOLFOX6 or FOLFIRI plus molecular targeted agent for 3 patients with unresectable locally advanced colorectal cancer with abscess formation.A 60-year-old man was diagnosed as having unresectable rectal cancer with abscess formation and underwent curative resection after partial response following chemotherapy.A 42-year-old woman was diagnosed as having unresectable sigmoid colon cancer with abscess formation and underwent curative resection after partial response following chemotherapy...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29573105/what-to-do-with-the-rectal-stump-during-sphincter-preserving-rectal-cancer-resection-with-end-colostomy-a-collaborative-snapshot-study
#7
E Westerduin, T S Aukema, A A W van Geloven, W A Bemelman, P J Tanis
AIM: Low Hartmann's resection (LHR) and intersphincteric abdominoperineal resection (iAPR) are both feasible options in the treatment of rectal cancer when restoration of bowel continuity is not desired. The aim of this study was to compare the incidence of pelvic abscess and associated need for re-intervention and readmission after LHR and iAPR. METHOD: From a snapshot research project in which all rectal cancer resections from 71 Dutch hospitals in 2011 were evaluated, patients who underwent LHR or iAPR were selected...
March 23, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29497909/vertical-rectus-abdominis-musculocutaneous-flap-repair-improves-perineal-wound-healing-after-abdominoperineal-resection-for-irradiated-locally-advanced-rectal-cancer
#8
Milan Spasojevic, Anthony B Mariathasan, Mariusz Goscinski, Ebbe B Thorgersen, Arne M Solbakken, Hans-Petter Gullestad, Truls Ryder, Kjersti Flatmark, Stein G Larsen
BACKGROUND: Radiotherapy (RT) and subsequent abdominoperineal resection (APR) for locally advanced rectal cancer (LARC) is associated with significant perineal wound morbidity. The aim of the present study was to investigate if vertical rectus abdominis musculocutaneous (VRAM) flap repair after APR in LARC patients improves perineal wound healing compared with direct perineal wound closure (non-VRAM). METHODS: LARC patients (n = 329) operated with APR between January 2006 and December 2015 after neoadjuvant RT of ≥ 25 Gy were identified, including 260 and 69 patients in the non-VRAM and VRAM groups, respectively...
May 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29394715/-results-of-neoadjuvant-chemoradiotherapy-for-rectal-cancer-with-invasion-to-the-adjacent-organs
#9
Harunobu Sato, Yoshikazu Koide, Miho Shiota, Masahiro Mizuno, Zenichi Morise, Ichiro Uyama
We reviewed the clinical records of 14 cases who received neoadjuvant chemoradiotherapy(CRT)to evaluate the clinical effectiveness of the CRT for T4b rectal cancer. The preoperative radiotherapy consisted of 40-50 Gy delivered in fractions of 1.8-2.0 Gy per day, 5 days per week. A treatment with intravenous 5-fluorouracil, or oral tegafur-uracil(UFT)with l-leucovorin, or oral S-1, or capecitabine or intravenous irinotecan with oral S-1, was administered during radiotherapy. One patient died due to pelvic abscess at 69 days after CRT...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394675/-a-case-of-locally-advanced-rectal-cancer-with-abscess-and-rectovesical-fistula-curatively-resected-following-preoperative-chemotherapy
#10
Tatsuya Matsumoto, Masayoshi Nakanishi, Mahito Miyamae, Koji Takao, Tomohiko Fukunaga, Eigo Otsuji
A 63-year-old man with bloody stools, anal incompetence, and feeling of fatigue was diagnosed as having a RAS mutanttype rectal cancer with abscess and rectovesical fistula. Computed tomography revealed that the tumor had invaded the seminal vesicle, prostate, and bladder and formed an abscess. In addition, his general condition was poor. Thus, we evaluated the lesion as unresectable. His nutritional status improved, and the infection was controlled after colostomy. Then, we performed chemotherapy with 5-fluorouracil, Leucovorin, and oxaliplatin(FOLFOX)plus bevacizumab...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29364005/purulent-myositis-of-the-thigh-as-a-presentation-of-perforated-low-rectal-cancer
#11
V Jenkins, J Steinke, N Rajendran, D Kumar
Purulent myositis is an acute, intramuscular bacterial infection involving abscess formation most commonly affecting the quadriceps, hamstring and gluteal muscles. We present a case of extensive purulent myositis of the thigh and lower leg caused by bowel perforation below the peritoneal reflection secondary to rectal cancer. Cases of lower limb and perineal purulent myositis should raise suspicion of rectal perforation and should prompt investigations to exclude rectal malignancy.
March 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29315090/incidence-and-risk-factors-for-anastomotic-failure-in-1594-patients-treated-by-transanal-total-mesorectal-excision-results-from-the-international-tatme-registry
#12
Marta Penna, Roel Hompes, Steve Arnold, Greg Wynn, Ralph Austin, Janindra Warusavitarne, Brendan Moran, George B Hanna, Neil J Mortensen, Paris P Tekkis
OBJECTIVE: To determine the incidence of anastomotic-related morbidity following Transanal Total Mesorectal Excision (TaTME) and identify independent risk factors for failure. BACKGROUND: Anastomotic leak and its sequelae are dreaded complications following gastrointestinal surgery. TaTME is a recent technique for rectal resection, which includes novel anastomotic techniques. METHODS: Prospective study of consecutive reconstructed TaTME cases recorded over 30 months in 107 surgical centers across 29 countries...
January 5, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29285682/efficacy-of-autologous-fat-graft-injection-in-the-treatment-of-anovaginal-fistulas
#13
S Norderval, L Lundby, H Hougaard, S Buntzen, S Weum, L de Weerd
BACKGROUND: Injection of autologous fat is an established method within plastic surgery for soft tissue augmentation. The aim of the present study was to determine whether transperineal fat graft injection could promote healing of anovaginal fistulas. METHODS: The procedures were performed at the University Hospital of North Norway, Tromsø, Norway, and at Aarhus University Hospital, Aarhus, Denmark, between May 2009 and September 2016. After abdominal liposuction, fat was injected around the fistula tract that was finally transected percutaneously with a sharp cannula and fat injected between the cut parts...
January 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29235007/snapshot-study-on-the-value-of-omentoplasty-in-abdominoperineal-resection-with-primary-perineal-closure-for-rectal-cancer
#14
Robin D Blok, Gijsbert D Musters, Wernard A A Borstlap, Christianne J Buskens, Wilhelmus A Bemelman, Pieter J Tanis
BACKGROUND: Perineal wound complications are often encountered following abdominoperineal resection (APR). Filling of the pelvic space by omentoplasty (OP) might prevent these complications, but there is scant evidence to support its routine application. OBJECTIVE: The aim of this study was to evaluate the impact of OP on perineal wound complications. METHODS: All patients undergoing APR with primary perineal closure (PPC) for non-locally advanced rectal cancer in 71 Dutch centers in 2011 were selected from a cross-sectional snapshot study...
March 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29232537/laparoscopic-versus-conventional-open-surgery-in-intersphincteric-resection-for-low-rectal-cancer-a-systematic-review-and-meta-analysis
#15
Xubing Zhang, Qingbin Wu, Tao Hu, Chaoyang Gu, Liang Bi, Ziqiang Wang
AIM: This meta-analysis aims at comparing laparoscopic intersphincteric resection (LISR) with conventional open ISR (OISR) for low rectal cancer (LRC) in terms of intraoperative, postoperative, pathological, and survival outcomes. MATERIALS AND METHODS: A systematic literature search with no limits was performed in PubMed and Ovid. The last search was performed on May 27, 2017. The outcomes of interests included intraoperative outcomes: operative time and blood loss; postoperative outcomes: hospital day, postoperative hospital day, time to first flatus, time to normal diet, ileus, intra-abdominal abscess, anastomotic leakage, anastomotic stricture, wound infection, pneumonia, urinary complication, morbidity, and mortality; pathological outcomes: lymph node harvested, R0 resection rate, distance of proximal resection margin, distal resection margin and circumferential resection margin (CRM), and positive CRM; survival outcomes: 3-year overall survival (OS), 3-year disease-free survival (DFS), 5-year OS, and 5-year DFS...
February 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29221920/treatment-of-infected-aneurysm-with-combined-endovascular-aneurysm-repair-and-abscess-drainage
#16
Ken Nakajima, Noriyuki Kato, Takashi Hashimoto, Shuji Chino, Takatoshi Higashigawa, Takafumi Ouchi, Toshiya Tokui, Yoichiro Miyake, Hajime Sakuma
PURPOSE: To evaluate the clinical utility of combination therapy with endovascular aneurysm repair (EVAR) and abscess drainage for the treatment of infected aneurysms. MATERIALS AND METHODS: Between July 2009 and May 2015, 8 patients underwent combination therapy with EVAR and abscess drainage. There were 5 men and 3 women, with a mean age of 75 years ± 7. Aneurysms were of the thoracic aorta in 5 patients, the abdominal aorta in 2, and the internal iliac artery in 1...
February 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29203149/improved-rectal-dosimetry-with-the-use-of-spaceoar-during-high-dose-rate-brachytherapy
#17
Susan Y Wu, Lauren Boreta, Ashley Wu, Joey P Cheung, J Adam M Cunha, Katsuto Shinohara, Albert J Chang
PURPOSE: Hydrogel spacers have been suggested to limit rectal radiation dose with improvements in clinical outcomes in patients undergoing external beam radiation treatment for prostate cancer. No studies to date have assessed the utility and dosimetric effect of SpaceOAR (Augmenix, Inc, Waltham, MA), the only Food and Drug Administration-approved hydrogel rectal spacer, for high-dose-rate (HDR) brachytherapy. METHODS: Eighteen consecutive patients scheduled for HDR brachytherapy in the treatment of prostate cancer underwent transperineal ultrasound-guided placement of 10 cc of SpaceOAR hydrogel following catheter implantation...
March 2018: Brachytherapy
https://www.readbyqxmd.com/read/29118559/long-term-efficacy-of-vacuum-assisted-therapy-endo-sponge-%C3%A2-in-large-anastomotic-leakages-following-anterior-rectal-resection
#18
Alessandro Mussetto, Rosario Arena, Andrea Buzzi, Lorenzo Fuccio, Silvia Dari, Mario Luciano Brancaccio, Omero Triossi
Background: The aim of our study was to test the long-term efficacy of Endo-SPONGE® therapy in a group of patients treated in our center with vacuum-assisted therapy because of anastomotic leakages after colorectal surgery. Methods: Eleven patients [male: 6; mean age: 71 (range: 44-82) years] who had anastomotic leakage treated with Endo-SPONGE® placement were included in the study. Patient records were examined retrospectively. All patients with documented anastomotic leakage on abdominal computed tomography following an anterior resection of the rectum for rectal cancer underwent sigmoidoscopy to determine the extent of the anastomotic defect and the size of the presacral abscess...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29114614/preoperative-radiation-dose-escalation-for-rectal-cancer-using-a-concomitant-boost-strategy-improves-tumor-downstaging-without-increasing-toxicity-a-matched-pair-analysis
#19
Jillian R Gunther, Awalpreet S Chadha, Ui Sup Shin, In Ja Park, Kiran V Kattepogu, Jonathan D Grant, David C Weksberg, Cathy Eng, Scott E Kopetz, Prajnan Das, Marc E Delclos, Harmeet Kaur, Dipen M Maru, John M Skibber, Miguel A Rodriguez-Bigas, Y Nancy You, Sunil Krishnan, George J Chang
Purpose: Pathologic complete response to neoadjuvant chemoradiation therapy (CRT) is associated with improved outcomes for patients with locally advanced rectal cancer (LARC). Increased response rates have been reported with higher radiation doses, but these studies often lack long-term outcome and/or toxicity data. We conducted a case-control analysis of patients with LARC who underwent definitive CRT to determine the efficacy and safety of intensified treatment with a concomitant boost (CB) approach...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28916971/emergency-room-visits-and-readmissions-following-implementation-of-an-enhanced-recovery-after-surgery-ieras-program
#20
Trevor Wood, Mary-Anne Aarts, Allan Okrainec, Emily Pearsall, J Charles Victor, Marg McKenzie, Ori Rotstein, Robin S McLeod
BACKGROUND: Enhanced Recovery After Surgery (ERAS) guidelines have been widely promoted and supported largely due to several studies showing decreased post-operative complications and length of stay. The objective of this study was to review the emergency room (ER) visits and readmission rates and reasons for both in patients who were part of the Implementation of an Enhanced Recovery After Surgery (iERAS) program for colorectal surgery. METHODS: All patients having elective colorectal surgery at 15 academic hospitals were enrolled in the iERAS program...
February 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
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