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https://www.readbyqxmd.com/read/28344637/growth-curve-registration-for-evaluating-salinity-tolerance-in-barley
#1
Rui Meng, Stephanie Saade, Sebastian Kurtek, Bettina Berger, Chris Brien, Klaus Pillen, Mark Tester, Ying Sun
BACKGROUND: Smarthouses capable of non-destructive, high-throughput plant phenotyping collect large amounts of data that can be used to understand plant growth and productivity in extreme environments. The challenge is to apply the statistical tool that best analyzes the data to study plant traits, such as salinity tolerance, or plant-growth-related traits. RESULTS: We derive family-wise salinity sensitivity (FSS) growth curves and use registration techniques to summarize growth patterns of HEB-25 barley families and the commercial variety, Navigator...
2017: Plant Methods
https://www.readbyqxmd.com/read/28338916/violent-offenders-respond-to-provocations-with-high-amygdala-and-striatal-reactivity
#2
Sofi da Cunha-Bang, Patrick MacDonald Fisher, Liv Vadskjær Hjordt, Erik Perfalk, Anine Persson Skibsted, Camilla Bock, Anders Ohlhues Baandrup, Marie Deen Christensen, Carsten Thomsen, Dorte Sestoft, Gitte M Knudsen
The ability to successfully suppress impulses and angry affect is fundamental to control aggressive reactions following provocations. The aim of this study was to examine neural responses to provocations and aggression using a laboratory model of reactive aggression. We used a novel functional magnetic resonance imaging point-subtraction aggression paradigm in 44 men, of whom 18 were incarcerated violent offenders and 26 were control non-offenders. We measured brain activation following provocations (monetary subtractions), while the subjects had the possibility to behave aggressively or pursue monetary rewards...
March 8, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28335481/genetic-variants-contributing-to-colistin-cytotoxicity-identification-of-tgif1-and-hoxd10-using-a-population-genomics-approach
#3
Michael T Eadon, Ronald J Hause, Amy L Stark, Ying-Hua Cheng, Heather E Wheeler, Kimberly S Burgess, Eric A Benson, Patrick N Cunningham, Robert L Bacallao, Pierre C Dagher, Todd C Skaar, M Eileen Dolan
Colistin sulfate (polymixin E) is an antibiotic prescribed with increasing frequency for severe Gram-negative bacterial infections. As nephrotoxicity is a common side effect, the discovery of pharmacogenomic markers associated with toxicity would benefit the utility of this drug. Our objective was to identify genetic markers of colistin cytotoxicity that were also associated with expression of key proteins using an unbiased, whole genome approach and further evaluate the functional significance in renal cell lines...
March 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28334822/posigene-automated-and-easy-to-use-pipeline-for-genome-wide-detection-of-positively-selected-genes
#4
Arne Sahm, Martin Bens, Matthias Platzer, Karol Szafranski
Many comparative genomics studies aim to find the genetic basis of species-specific phenotypic traits. A prevailing strategy is to search genome-wide for genes that evolved under positive selection based on the non-synonymous to synonymous substitution ratio. However, incongruent results largely due to high false positive rates indicate the need for standardization of quality criteria and software tools. Main challenges are the ortholog and isoform assignment, the high sensitivity of the statistical models to alignment errors and the imperative to parallelize large parts of the software...
March 15, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28330293/effect-of-reduced-plant-height-on-drought-tolerance-in-rice
#5
Asadollah Ahmadikhah, Amir Marufinia
Drought stress due to water deficit is a major problem of rice cultivation as a most drought-sensitive crop plant. A rice mutant line (MT58) was developed after mutagenesis of cv. Neda by ethyl methane sulfonate (EMS) and selected for dwarfism (18 cm shorter than Neda). The extent of its molecular changes relative to parental cultivar was assessed by SSR and ISSR markers, and the response of the line along with parental cultivar and another mutant line (MTA) to mild and severe water deficit, was evaluated in a field experiment...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28317384/exploring-possible-predictors-and-moderators-of-an-executive-function-training-for-children-with-an-autism-spectrum-disorder
#6
Marieke de Vries, Mathilde Ge Verdam, Pier Jm Prins, Ben A Schmand, Hilde M Geurts
Previously, a total of 121 children with an autism spectrum disorder (ASD) performed an adaptive working memory (WM)-training, an adaptive flexibility-training, or a non-adaptive control (mock)-training. Despite overall improvement, there were minor differences between the adaptive and mock-training conditions. Moreover, dropout was relatively high (26%). In the current study we explored potential predicting and moderating factors to clarify these findings. The effects of intelligence, autism traits, WM, flexibility, reward sensitivity and Theory of Mind on dropout, improvement during training, and improvement in everyday executive functioning (EF), ASD-like behavior, and Quality of Life (QoL) were studied...
March 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28293708/inverse-gene-for-gene-interactions-contribute-additively-to-tan-spot-susceptibility-in-wheat
#7
Zhaohui Liu, Jason D Zurn, Gayan Kariyawasam, Justin D Faris, Gongjun Shi, Jana Hansen, Jack B Rasmussen, Maricelis Acevedo
Tan spot susceptibility is conferred by multiple interactions of necrotrophic effector and host sensitivity genes. Tan spot of wheat, caused by Pyrenophora tritici-repentis, is an important disease in almost all wheat-growing areas of the world. The disease system is known to involve at least three fungal-produced necrotrophic effectors (NEs) that interact with the corresponding host sensitivity (S) genes in an inverse gene-for-gene manner to induce disease. However, it is unknown if the effects of these NE-S gene interactions contribute additively to the development of tan spot...
March 14, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28289420/evaluation-of-exotically-derived-soybean-breeding-lines-for-seed-yield-germination-damage-and-composition-under-dryland-production-in-the-midsouthern-usa
#8
Nacer Bellaloui, James R Smith, Alemu Mengistu, Jeffery D Ray, Anne M Gillen
Although the Early Soybean Production System (ESPS) in the Midsouthern USA increased seed yield under irrigated and non-irrigated conditions, heat stress and drought still lead to poor seed quality in heat sensitive soybean cultivars. Our breeding goal was to identify breeding lines that possess high germination, nutritional quality, and yield potential under high heat and dryland production conditions. Our hypothesis was that breeding lines derived from exotic germplasm might possess physiological and genetic traits allowing for higher seed germinability under high heat conditions...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28287610/multivariate-simulation-framework-reveals-performance-of-multi-trait-gwas-methods
#9
Heather F Porter, Paul F O'Reilly
Burgeoning availability of genome-wide association study (GWAS) results and national biobank data has led to growing interest in performing multi-trait genetic analyses. Numerous multi-trait GWAS methods that exploit either summary statistics or individual-level data have been developed, but their relative performance is unclear. Here we develop a simulation framework to model the complex networks underlying multivariate genetic epidemiology, enabling the vast model space of genetic effects on multiple correlated traits to be explored systematically...
March 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28285148/acute-variations-of-cytokine-levels-after-antipsychotic-treatment-in-drug-na%C3%A3-ve-subjects-with-a-first-episode-psychosis-a-meta-analysis
#10
REVIEW
Enrico Capuzzi, Francesco Bartoli, Cristina Crocamo, Massimo Clerici, Giuseppe Carrà
Schizophrenia is likely to be associated with immunological abnormalities. However, antipsychotics may induce immunomodulatory effects, by influencing plasma cytokines. In order to distinguish these influences, we carried out a systematic review and meta-analysis exploring the acute effect of antipsychotics on candidate cytokines plasma levels (IL-1β, IL-2, IL-6, IL-17, IFN-γ, TNF-α) among drug-naïve subjects with first episode psychosis. We searched main Electronic Databases, identifying eight studies meeting our inclusion criteria...
March 8, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28282524/effectiveness-of-a-selective-alcohol-prevention-program-targeting-personality-risk-factors-results-of-interaction-analyses
#11
Jeroen Lammers, Ferry Goossens, Patricia Conrod, Rutger Engels, Reinout W Wiers, Marloes Kleinjan
AIM: To explore whether specific groups of adolescents (i.e., scoring high on personality risk traits, having a lower education level, or being male) benefit more from the Preventure intervention with regard to curbing their drinking behaviour. DESIGN: A clustered randomized controlled trial, with participants randomly assigned to a 2-session coping skills intervention or a control no-intervention condition. SETTING: Fifteen secondary schools throughout The Netherlands; 7 schools in the intervention and 8 schools in the control condition...
February 28, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28280551/parasite-vulnerability-to-climate-change-an-evidence-based-functional-trait-approach
#12
REVIEW
Carrie A Cizauskas, Colin J Carlson, Kevin R Burgio, Chris F Clements, Eric R Dougherty, Nyeema C Harris, Anna J Phillips
Despite the number of virulent pathogens that are projected to benefit from global change and to spread in the next century, we suggest that a combination of coextinction risk and climate sensitivity could make parasites at least as extinction prone as any other trophic group. However, the existing interdisciplinary toolbox for identifying species threatened by climate change is inadequate or inappropriate when considering parasites as conservation targets. A functional trait approach can be used to connect parasites' ecological role to their risk of disappearance, but this is complicated by the taxonomic and functional diversity of many parasite clades...
January 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28261330/radiation-capture-and-conversion-efficiencies-of-miscanthus-sacchariflorus-m-%C3%A2-sinensis-and-their-naturally-occurring-hybrid-m-%C3%A2-%C3%A3-%C3%A2-giganteus
#13
Christopher Lyndon Davey, Laurence Edmund Jones, Michael Squance, Sarah Jane Purdy, Anne Louise Maddison, Jennifer Cunniff, Iain Donnison, John Clifton-Brown
Miscanthus is a rhizomatous C4 grass of great interest as a biofuel crop because it has the potential to produce high yields over a wide geographical area with low agricultural inputs on marginal land less suitable for food production. At the moment, a clonal interspecific hybrid Miscanthus × giganteus is the most widely cultivated and studied in Europe and the United States, but breeding programmes are developing newer more productive varieties. Here, we quantified the physiological processes relating to whole season yield in a replicated plot trial in Wales, UK...
February 2017: Global Change Biology. Bioenergy
https://www.readbyqxmd.com/read/28261226/transcriptomic-analysis-reveals-new-insights-into-high-temperature-dependent-glume-unclosing-in-an-elite-rice-male-sterile-line
#14
Chongyun Fu, Feng Wang, Wuge Liu, Dilin Liu, Jinhua Li, Manshan Zhu, Yilong Liao, Zhenrong Liu, Huijun Huang, Xueqin Zeng, Xiaozhi Ma
Glume-unclosing after anthesis is a widespread phenomenon in hybrid rice and also a maternal hereditary trait. The character of Glume-unclosing in rice male sterile lines also seriously influences germination rate and the commercial quality of hybrid rice seeds. We validated that the type of glume-unclosing after anthesis in the elite rice thermo-sensitive genic male sterile (TGMS) line RGD-7S was caused by high temperature. Transcriptomic sequencing of rice panicles was performed to explore the change of transcript profiles under four conditions: pre- and post-anthesis under high temperature (HRGD0 and HRGD1), and pre- and post-anthesis under low temperature (LRGD0 and LRGD1)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28258035/raising-the-alarm-individual-differences-in-the-perceptual-awareness-of-masked-facial-expressions
#15
Ljubica Damjanovic, Marcel Meyer, Francisco Sepulveda
A theoretical concern in addressing the unconscious perception of emotion is the extent to which participants can access experiential properties of masked facial stimuli. Performance on a two alternative forced choice (2AFC) task as a measure of objective awareness was compared with a new measure developed to access experiential phenomena of the target-mask transition, the perceptual contrast-change sensitivity (PCCS) measure in a backward-masking paradigm with angry, happy and neutral facial expressions. Whilst 2AFC performance indicated that the targets were successfully masked, PCCS values were significantly higher in the happy-neutral face condition than in the angry-neutral face and the neutral-neutral face conditions (Experiment 1)...
February 28, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28250586/physiological-performance-of-two-contrasting-rice-varieties-under-water-stress
#16
Furqan Khan, Priyanka Upreti, Ruchi Singh, Pradeep Kumar Shukla, Pramod Arvind Shirke
Two rice varieties PR-115 and Super-7 were imposed to water stress and different physiological traits were monitored to evaluate the performance of these varieties under drought. Under water stress condition although the relative water content, osmotic potential, chlorophyll content, photosynthesis rate, carbon discrimination and biomass decreased in both the varieties however, the reduction was more pronounced in Super-7 variety. Oryzanol a trans-ester of ferulic acid functions as antioxidant and it increased along with total phenolic and anthocyanin content in both the varieties under drought stress...
January 2017: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/28245894/plasma-apociii-levels-in-relation-to-inflammatory-traits-and-metabolic-syndrome-in-patients-not-treated-with-lipid-lowering-drugs-undergoing-coronary-angiography
#17
Na Qiong Wu, Sha Li, Yan Zhang, Cheng Gang Zhu, Yuan Lin Guo, Ying Gao, Ping Qing, Jing Sun, Geng Liu, Qian Dong, Jian Jun Li
OBJECTIVE: Assessment of the comprehensive relationship among apolipoprotein CIII (apoCIII) levels, inflammation, and metabolic disorders is rare. METHODS: A total of 1455 consecutive patients not treated with lipid-lowering drugs and undergoing coronary angiography were enrolled in this cross-sectional study. A mediation analysis was used to detect the underlying role of apoCIII in the association of inflammation with metabolic syndrome (MetS). RESULTS: Patients with MetS showed higher levels of apoCIII [95...
January 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28238365/the-well-sorted-fine-sand-community-from-the-western-mediterranean-sea-a-resistant-and-resilient-marine-habitat-under-diverse-human-pressures
#18
Jean-Claude Dauvin, Ali Bakalem, Alexandrine Baffreau, Claire Delecrin, Gérard Bellan, Claudio Lardicci, Elena Balestri, Rafael Sardá, Samir Grimes
The Biocoenosis of Well Sorted Fine Sands (WSFS) (SFBC, Sables Fins Bien Calibrés in French) is a Mediterranean community very well delimited by bathymetry (2-25 m) and sedimentology (>90% of fine sand) occurring in zones with relatively strong hydrodynamics. In this study focused on sites located along the Algerian, French, Italian and Spanish coasts of the Western Basin of the Mediterranean Sea (WBMS) we aim to compare the structure, ecological status and diversity of the macrofauna of the WSFS and examine the effects of recent human pressures on the state of this shallow macrobenthic community...
February 18, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28228253/sirt6-suppresses-cancer-stem-like-capacity-in-tumors-with-pi3k-activation-independently-of-its-deacetylase-activity
#19
Rafael M Ioris, Mirco Galié, Giorgio Ramadori, Jason G Anderson, Anne Charollais, Georgia Konstantinidou, Xavier Brenachot, Ebru Aras, Algera Goga, Nicholas Ceglia, Carlos Sebastián, Denis Martinvalet, Raul Mostoslavsky, Pierre Baldi, Roberto Coppari
Cancer stem cells (CSCs) have high tumorigenic capacity. Here, we show that stem-like traits of specific human cancer cells are reduced by overexpression of the histone deacetylase sirtuin 6 (SIRT6). SIRT6-sensitive cancer cells bear mutations that activate phosphatidylinositol-3-kinase (PI3K) signaling, and overexpression of SIRT6 reduces growth, progression, and grade of breast cancer in a mouse model with PI3K activation. Tumor metabolomic and transcriptomic analyses reveal that SIRT6 overexpression dampens PI3K signaling and stem-like characteristics and causes metabolic rearrangements in this cancer model...
February 21, 2017: Cell Reports
https://www.readbyqxmd.com/read/28226305/effect-of-maternal-rumination-and-disengagement-during-childhood-on-offspring-neural-response-to-reward-in-late-adolescence
#20
Judith K Morgan, Daniel S Shaw, Rachel H Jacobs, Sarah E Romens, Stephanie L Sitnick, Erika E Forbes
Maternal rumination is a cognitive-affective trait that could influence offspring's ability to respond flexibly to positive and negative events, depending on the quality of maternal problem-solving behaviors with which rumination co-occurs. As reward circuitry is sensitive to stressors and related to risk for depression, reward circuitry is an appropriate candidate mechanism for how maternal characteristics influence offspring. We evaluated the independent and combined effect of maternal rumination and disengagement on adolescent neural response to reward win and loss...
February 11, 2017: Psychiatry Research
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