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Latent growth mixture modeling

Akihito Kamata, Yusuf Kara, Chalie Patarapichayatham, Patrick Lan
This study investigated the performance of three selected approaches to estimating a two-phase mixture model, where the first phase was a two-class latent class analysis model and the second phase was a linear growth model with four time points. The three evaluated methods were (a) one-step approach, (b) three-step approach, and (c) case-weight approach. As a result, some important results were demonstrated. First, the case-weight and three-step approaches demonstrated higher convergence rate than the one-step approach...
2018: Frontiers in Psychology
Yu-Chung Lawrence Wang, Hsun-Yu Chan, Pei-Chun Chen
We investigated the heterogeneous developmental trajectories of depressive symptoms in junior and senior high school, the transitions to different trajectories after entering senior high school, and the linkages to the development of depressive symptoms in early adulthood among Taiwanese adolescents. An eight-wave longitudinal data set was analyzed, including 2687 Taiwanese adolescents (51.2% boys, M age = 14.3 at first wave). Using a manual three-step latent transition growth mixture model, we found that a three-class solution fit the data for both junior high school (termed high-improving, cumulative, and JS-low-stable) and senior high school period (termed heightening, moderate-stable, and HS-low-stable)...
February 21, 2018: Journal of Abnormal Child Psychology
Camille Lassale, G David Batty, Andrew Steptoe, Dorina Cadar, Tasnime N Akbaraly, Mika Kivimäki, Paola Zaninotto
Background: Elevated systematic inflammation is a hallmark of aging, but the association of long-term inflammation trajectories with subsequent aging phenotypes has been little examined. We assessed inflammatory marker C-reactive protein (CRP) repeatedly over time and examined whether long-term changes predicted aging outcomes. Methods: A total of 2,437 men and women aged 47-87 years at baseline (1998-2001) who were participants in the English Longitudinal Study of Ageing had CRP measured on two or three occasions between 1998 and 2009...
February 15, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Jonathan P Auld, James O Mudd, Jill M Gelow, Karen S Lyons, Shirin O Hiatt, Christopher S Lee
BACKGROUND: Both heart failure symptoms and self-care are associated with patient outcomes. Although it is thought that symptoms drive self-care, there is limited evidence to support this assumption over time. AIMS: To determine whether patterns of physical symptoms are significantly associated with heart failure self-care over time. METHOD: Latent mixture analysis was used to identify subgroups based on physical symptoms of dyspnea, sleepiness and edema (using the heart failure somatic perception and Epworth sleepiness scales)...
February 1, 2018: European Journal of Cardiovascular Nursing
Derek Kenji Iwamoto, William Corbin, Jennifer Brady, Margaux Grivel, Lauren Clinton, Aylin Kaya, Carl Lejuez
BACKGROUND: Heavy episodic drinking (HED; 4 or more drinks in a 2-hour period) in U.S. college women has increased by 40% in the past 30 years. This dramatic shift suggests that women are "closing the gender gap" and are drinking at rates similar to men. Multidimensional feminine norms, or beliefs and expectations about what it means to be a woman, are theoretically promising and gender-relevant factors that may help account for within-group differences in problematic drinking patterns among this increasingly at-risk group...
February 7, 2018: Alcoholism, Clinical and Experimental Research
Cindy-Lee Dennis, Sarah Brennenstuhl, Susitha Wanigaratne, Hilary K Brown, Sophie Grigoriadis, Flavia C Marini, Simone N Vigod
BACKGROUND: Our objectives were to identify subtypes of Chinese-Canadian women with unique trajectories of anxiety symptomatology over the first postpartum year, investigate covariates associated with group membership, and determine if mental healthcare utilization varies by group membership. METHODS: This was a longitudinal cohort study of 570 Chinese immigrant and Canadian-born women in Toronto, Canada with live births in 2010-2014. Covariates were age, immigrant status, income, fatigue, social support, acculturative stress, and depression...
January 26, 2018: Journal of Affective Disorders
Jong Won Min
OBJECTIVE: The purpose of this study is twofold: first, to identify cognitive trajectories of older Koreans in a population-based longitudinal panel survey and, second, to investigate the main characteristics of the identified heterogeneous classes of cognitive trajectories. METHODS: Data came from 2445 cognitively healthy persons aged 60 or older in the 2006 to 2012 Korean Longitudinal Study of Aging. Using Korean-mini mental status examination (K-MMSE) as a measure of global cognitive function, the latent growth mixture modeling approach examined potential heterogeneity of longitudinal changes over the 6 years...
January 24, 2018: International Journal of Geriatric Psychiatry
Javier de la Fuente, Francisco Félix Caballero, Albert Sánchez-Niubó, Demosthenes B Panagiotakos, Matthew A Prina, Holger Arndt, Josep Maria Haro, Somnath Chatterji, José Luis Ayuso-Mateos
Background: Aging is a multidimensional process with a remarkable inter-individual variability. This study is focused on identifying groups of population with similar aging patterns, and to define the health trajectories of these groups. Socio-demographic and health determinants of these trajectories are also identified. Methods: Data from the English Longitudinal Study of Aging (ELSA) and the Health and Retirement Study (HRS) were used. A set of self-reported health items and measured tests were used to generate a latent health metric by means of a Bayesian multilevel IRT model, assessing the ability of the metric to predict mortality...
January 16, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Rens van de Schoot, Marit Sijbrandij, Sarah Depaoli, Sonja D Winter, Miranda Olff, Nancy E van Loey
There is a recent increase in interest of Bayesian analysis. However, little effort has been made thus far to directly incorporate background knowledge via the prior distribution into the analyses. This process might be especially useful in the context of latent growth mixture modeling when one or more of the latent groups are expected to be relatively small due to what we refer to as limited data. We argue that the use of Bayesian statistics has great advantages in limited data situations, but only if background knowledge can be incorporated into the analysis via prior distributions...
January 11, 2018: Multivariate Behavioral Research
Lone Hellström, Trine Madsen, Merete Nordentoft, Per Bech, Lene Falgaard Eplov
Purpose The return to work (RTW) of people with mood and anxiety disorders is a heterogeneous process. We aimed to identify prototypical trajectories of RTW over a two-year period in people on sick leave with mood and anxiety disorders, and investigate if socio-demographic or clinical factors predicted trajectory membership. Methods We used data from the randomized IPS-MA trial (n = 283), evaluating a supported employment intervention for participants with recently diagnosed mood or anxiety disorders. Information on "weeks in employment in the past 6 months" was measured after 1/2, 1, 1 ½ and 2 years, using data from a nationwide Danish register (DREAM)...
December 27, 2017: Journal of Occupational Rehabilitation
Guido Alessandri, Enrico Perinelli, Evelina De Longis, Annalisa Theodorou
In recent years, research in organizational psychology has witnessed a shift in attention from a mostly variable-focused approach, to a mostly person-focused approach. Indeed, it has been widely recognized that the study of worker's heterogeneity is a meaningful and necessary task of researchers dealing with human behavior in organizational contexts. As a consequence, there has been growing interest in the application of statistical analyses able to uncover latent sub-groups of workers. The present contribution was conceived as a tutorial for the application of one of these statistical analyses, namely second-order growth mixture modeling, and to illustrate its inner links with concepts from non-linear dynamic models...
January 2018: Nonlinear Dynamics, Psychology, and Life Sciences
Lance M Rappaport, Christina Sheerin, Dever M Carney, Kenneth E Towbin, Ellen Leibenluft, Daniel S Pine, Melissa A Brotman, Roxann Roberson-Nay, John M Hettema
OBJECTIVE: Hypersensitivity to carbon dioxide (CO2 )-enriched air may be a promising risk marker for anxiety disorders. Among adult and adolescent samples, heterogeneity in distress response to the CO2 challenge task indexes 3 underlying classes of individuals, which distinguish between sustained and acute threat response as markers for internalizing disorders, broadly, and anxiety disorders, specifically. The present study examines latent classes in children's response to the CO2 challenge task to clarify the association of CO2 hypersensitivity with anxiety and internalizing symptomatology in childhood...
December 2017: Journal of the American Academy of Child and Adolescent Psychiatry
A Feleus, H S Miedema, S M A Bierma-Zeinstra, T Hoekstra, B W Koes, A Burdorf
OBJECTIVES: Impediments due to complaints of non-traumatic arm, neck and/or shoulder (CANS) during work often leads to consultation in primary care. This study examines the occurrence of sick leave among workers with new CANS, and evaluates sick leave trajectories and their characteristics. METHODS: This prospective 2-year cohort study included workers with a new CANS presenting in general practice. Participants filled out postal questionnaires on sick leave at 6-monthly intervals...
2017: Nederlands Tijdschrift Voor Geneeskunde
Eric F Lock, Nidhi Kohli, Maitreyee Bose
Piecewise growth mixture models are a flexible and useful class of methods for analyzing segmented trends in individual growth trajectory over time, where the individuals come from a mixture of two or more latent classes. These models allow each segment of the overall developmental process within each class to have a different functional form; examples include two linear phases of growth, or a quadratic phase followed by a linear phase. The changepoint (knot) is the time of transition from one developmental phase (segment) to another...
November 17, 2017: Psychometrika
Paul A McDermott, Michael J Rovine, Marley W Watkins, Jessica L Chao, Clare W Irwin, Roland Reyes
This research examined the latent developmental patterns for early classroom disengagement among children from some of the most underresourced families in the nation. Based on standardized teacher observations from the Head Start Impact Study, a nationally representative sample of children (N=1377) was assessed for manifestations of reticent/withdrawn and low energy behavior over four years spanning prekindergarten through first grade. For each form of disengagement, latent growth mixture modeling revealed three distinct subpopulations of change patterns featuring a dominant class associated with generally good classroom adjustment, a medial class that varied close to the population average over time, and a more extreme class (about 10% of the population) whose adjustment was relatively marginal and sometimes reached problematic levels...
December 2017: Journal of School Psychology
A J Phelps, Z Steel, O Metcalf, N Alkemade, K Kerr, M O'Donnell, J Nursey, J Cooper, A Howard, R Armstrong, D Forbes
BACKGROUND: To determine the patterns and predictors of treatment response trajectories for veterans with post-traumatic stress disorder (PTSD). METHODS: Conditional latent growth mixture modelling was used to identify classes and predictors of class membership. In total, 2686 veterans treated for PTSD between 2002 and 2015 across 14 hospitals in Australia completed the PTSD Checklist at intake, discharge, and 3 and 9 months follow-up. Predictor variables included co-morbid mental health problems, relationship functioning, employment and compensation status...
November 15, 2017: Psychological Medicine
Dorijn Fl Hertroijs, Arianne Mj Elissen, Martijn Cgj Brouwers, Nicolaas C Schaper, Sebastian Köhler, Mirela C Popa, Stylianos Asteriadis, Steven H Hendriks, Henk J Bilo, Dirk Ruwaard
AIM: To identify, predict and validate distinct glycemic trajectories among patients with newly diagnosed type 2 diabetes treated in primary care, as a first step towards more effective patient-centred care. MATERIAL AND METHODS: We conducted a retrospective study on two cohorts using routinely collected individual patient data in primary care practices from two large Dutch diabetes patient registries. Participants included newly diagnosed, adult patients with type 2 diabetes between January 2006 and December 2014 (n = 10,528, development cohort; n = 3,777, validation cohort)...
November 2, 2017: Diabetes, Obesity & Metabolism
Yvonne Tran, Elaine Blumgart, Ashley Craig
PURPOSE: Many adults who stutter have elevated negative mood states like anxiety and depressive mood. Little is known about how mood states change over time. The purpose of this study was to determine the trajectories or sub-types of mood states in adults who stutter over a 6 month period, and establish factors that contribute to these sub-types. METHOD: Participants included 129 adults who stutter who completed an assessment regimen at baseline, including a measure of mood states (Symptom Checklist-90-Revised)...
October 28, 2017: Journal of Fluency Disorders
Meagan Whisenant, Bob Wong, Sandra A Mitchell, Susan L Beck, Kathi Mooney
PURPOSE/OBJECTIVES: To examine self-reported severity of fatigue and disturbed sleep experienced daily by women with breast cancer during multiple cycles of chemotherapy, exploring potential classes of women experiencing similar symptom trajectories.
. DESIGN: In a secondary analysis, classes of women experiencing similar patterns of fatigue and disturbed sleep were identified.
. SETTING: Oncology clinics in the United States.
. SAMPLE: 166 women with breast cancer receiving chemotherapy...
November 1, 2017: Oncology Nursing Forum
Carrie J Donoho, George A Bonanno, Ben Porter, Lauren Kearney, Teresa M Powell
Post-traumatic stress disorder (PTSD) is a common psychiatric disorder among service members and veterans. The clinical course of PTSD varies across individuals, and patterns of symptom development have yet to be clearly delineated. Previous studies have been limited by convenience sampling, short follow-up periods, and inability to account for combat-related trauma. To determine the trajectories of PTSD symptoms among deployed military personnel with and without combat exposure, we used data from a population-based representative sample of 8,178 US service members participating in the Millennium Cohort Study from 2001-2011...
September 27, 2017: American Journal of Epidemiology
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