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Latent growth mixture modeling

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https://www.readbyqxmd.com/read/28395158/clinical-characteristics-of-latent-classes-of-co2-hypersensitivity-in-adolescents-and-young-adults
#1
Lance M Rappaport, Christina Sheerin, Jeanne E Savage, John M Hettema, Roxann Roberson-Nay
Although breathing CO2-enriched air reliably increases anxiety, there is debate concerning the nature and specificity of CO2 hypersensitivity to panic risk and panic disorder versus anxiety disorders and related traits broadly, particularly among adolescents and emerging adults. The present study sought to clarify the association of CO2 hypersensitivity with internalizing conditions and symptoms among adolescents and young adults. Participants (N = 628) self-reported anxiety levels every 2 min while breathing air enriched to 7...
March 30, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28359031/emergence-of-depression-following-job-loss-prospectively-predicts-lower-rates-of-reemployment
#2
Catherine A Stolove, Isaac R Galatzer-Levy, George A Bonanno
Job loss has been associated with the emergence of depression and subsequent long-term diminished labor market participation. In a sample of 500 adults who lost their jobs, trajectories of depression severity from four years before to four years after job loss were identified using Latent Growth Mixture Modeling. Rates of unemployment by trajectory were compared at two and four years following job loss. Four trajectories demonstrated optimal model fit including resilience (72%), chronic pre-to-post job loss depression (9%), emergent depression (10%), and remitting depression (9%)...
March 22, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28329850/the-use-of-growth-mixture-modeling-for-studying-resilience-to-major-life-stressors-in-adulthood-and-old-age-lessons-for-class-size-and-identification-and-model-selection
#3
Frank J Infurna, Kevin J Grimm
Objectives: Growth mixture modeling (GMM) combines latent growth curve and mixture modeling approaches and is typically used to identify discrete trajectories following major life stressors (MLS). However, GMM is often applied to data that does not meet the statistical assumptions of the model (e.g., within-class normality) and researchers often do not test additional model constraints (e.g., homogeneity of variance across classes), which can lead to incorrect conclusions regarding the number and nature of the trajectories...
March 8, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28323285/utilization-of-machine-learning-for-prediction-of-post-traumatic-stress-a-re-examination-of-cortisol-in-the-prediction-and-pathways-to-non-remitting-ptsd
#4
I R Galatzer-Levy, S Ma, A Statnikov, R Yehuda, A Y Shalev
To date, studies of biological risk factors have revealed inconsistent relationships with subsequent post-traumatic stress disorder (PTSD). The inconsistent signal may reflect the use of data analytic tools that are ill equipped for modeling the complex interactions between biological and environmental factors that underlay post-traumatic psychopathology. Further, using symptom-based diagnostic status as the group outcome overlooks the inherent heterogeneity of PTSD, potentially contributing to failures to replicate...
March 21, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28318338/latent-class-profiles-of-anxiety-symptom-trajectories-from-preschool-through-school-age
#5
Sarah J Kertz, Chad Sylvester, Rebecca Tillman, Joan L Luby
Anxiety typically arises early in childhood and decreases during school age. However, little is known about the earlier developmental course of anxiety in preschool, especially in at risk children, posing a clinically important problem. Given that anxiety in youth has a chronic course for some and also predicts later development of other mental health problems, it is important to identify factors early in development that may predict chronic anxiety symptoms. At-risk children (oversampled for depression) and caregivers completed 6 assessment waves beginning at preschool age (between 3-5...
March 20, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28318274/do-multiple-health-events-reduce-resilience-when-compared-with-single-events
#6
Ruth T Morin, Isaac R Galatzer-Levy, Fiona Maccallum, George A Bonanno
OBJECTIVE: The impact of multiple major life stressors is hypothesized to reduce the probability of resilience and increase rates of mortality. However, this hypothesis lacks strong empirical support because of the lack of prospective evidence. This study investigated whether experiencing multiple major health events diminishes rates of resilience and increases rates of mortality using a large population-based prospective cohort. METHOD: There were n = 1,395 individuals sampled from the Health and Retirement Study (HRS) and examined prospectively from 2 years before 4 years after either single or multiple health events (lung disease, heart disease, stroke, or cancer)...
March 20, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28288530/trajectories-of-health-related-quality-of-life-after-stroke-results-from-a-one-year-prospective-cohort-study
#7
Maria van Mierlo, Caroline van Heugten, Marcel W M Post, Trynke Hoekstra, Anne Visser-Meily
PURPOSE: To identify trajectories of physical and psychosocial health-related quality of life (HRQoL) from two months to one-year post stroke and to determine the factors that are associated with trajectory membership. METHOD: Multicenter prospective cohort study in which 351 stroke patients were followed up at 2, 6, and 12 months post stroke. Latent class growth mixture modeling was used to determine trajectories of physical and psychosocial HRQoL. Multinomial regression analyses were performed to predict trajectory membership...
March 13, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28277038/has-growth-mixture-modeling-improved-our-understanding-of-how-early-change-predicts-psychotherapy-outcome
#8
Andrew Koffmann
OBJECTIVE: Early change in psychotherapy predicts outcome. Seven studies have used growth mixture modeling [GMM; Muthén, B. (2001). Second-generation structural equation modeling with a combination of categorical and continuous latent variables: New opportunities for latent class-latent growth modeling. In L. M. Collins & A. G. Sawyers (Eds.), New methods for the analysis of change (pp. 291-322). Washington, DC: American Psychological Association] to identify patient classes based on early change but have yielded conflicting results...
March 2, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/28182961/prospective-post-traumatic-stress-disorder-symptom-trajectories-in-active-duty-and-separated-military-personnel
#9
Ben Porter, George A Bonanno, Melissa A Frasco, Erin K Dursa, Edward J Boyko
Post-traumatic stress disorder (PTSD) is a serious mental illness that affects current and former military service members at a disproportionately higher rate than the civilian population. Prior studies have shown that PTSD symptoms follow multiple trajectories in civilians and military personnel. The current study examines whether the trajectories of PTSD symptoms of veterans separated from the military are similar to continuously serving military personnel. The Millennium Cohort Study is a population-based study of military service members that commenced in 2001 with follow-up assessments occurring approximately every 3 years thereafter...
January 30, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28028741/can-universal-sel-programs-benefit-universally-effects-of-the-positive-action-program-on-multiple-trajectories-of-social-emotional-and-misconduct-behaviors
#10
Robert Duncan, Isaac J Washburn, Kendra M Lewis, Niloofar Bavarian, David L DuBois, Alan C Acock, Samuel Vuchinich, Brian R Flay
Behavioral trajectories during middle childhood are predictive of consequential outcomes later in life (e.g., substance abuse, violence). Social and emotional learning (SEL) programs are designed to promote trajectories that reflect both growth in positive behaviors and inhibited development of negative behaviors. The current study used growth mixture models to examine effects of the Positive Action (PA) program on behavioral trajectories of social-emotional and character development (SECD) and misconduct using data from a cluster-randomized trial that involved 14 schools and a sample of predominately low-income, urban youth followed from 3rd through 8th grade...
February 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28025095/a-cross-species-study-of-heterogeneity-in-fear-extinction-learning-in-relation-to-fkbp5-variation-and-expression-implications-for-the-acute-treatment-of-posttraumatic-stress-disorder
#11
Isaac R Galatzer-Levy, Raül Andero, Takehito Sawamura, Tanja Jovanovic, Santiago Papini, Kerry J Ressler, Seth Davin Norrholm
Deficits in fear extinction learning are hypothesized to underlie the development of posttraumatic stress disorder (PTSD). Such deficits may, in part, be due to genetic and epigenetic variation in the stress related gene FKBP5. Conversely, altering FKBP5 epigenetic responses during memory consolidation may rescue extinction deficits making it a target for acute intervention to prevent the development of PTSD. Study 1 (Humans) examines if FKBP5 single nucleotide polymorphisms (SNPs) and PTSD symptom domains (re-experiencing, avoidance/numbing, hyperarousal) are associated with abnormal fear extinction phenotypes identified using latent growth mixture modeling (LGMM)...
December 23, 2016: Neuropharmacology
https://www.readbyqxmd.com/read/28010168/bayesian-analysis-of-piecewise-growth-mixture-models-with-skew-t-distributions-application-to-aids-studies
#12
Getachew A Dagne, Boubakari Ibrahimou
A major problem in HIV/AIDS studies is the development of drug resistance to antiretroviral (ARV) drug or therapy. Estimating the time at which such drug resistance would develop is usually sought. The goal of this article is to perform this estimation by developing growth mixture models with change-points and skew-t distributions based on longitudinal data. For such data, following ARV treatment, the profile of each subject's viral load tends to follow a 'broken stick' like growth trajectory, indicating multiple phases of decline and increase in viral loads...
December 23, 2016: Journal of Biopharmaceutical Statistics
https://www.readbyqxmd.com/read/27991806/are-reductions-in-pain-intensity-and-pain-related-distress-necessary-an-analysis-of-within-treatment-change-trajectories-in-relation-to-improved-functioning-following-interdisciplinary-acceptance-and-commitment-therapy-for-adults-with-chronic-pain
#13
Kevin E Vowles, Katie Witkiewitz, Jayne Levell, Gail Sowden, Julie Ashworth
OBJECTIVE: A key issue in chronic pain treatment concerns the changes necessary for improved physical and emotional functioning. Traditionally, reducing pain intensity and pain-related distress have been viewed as a prerequisite for these improvements. Alternatively, acceptance and commitment therapy, a behavior change approach, theorizes that pain and distress reduction are not necessary for improvement, rather responses must change, such that functioning improves in clearly specified areas (e...
February 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/27990129/developmental-trajectories-of-sleep-problems-from-childhood-to-adolescence-both-predict-and-are-predicted-by-emotional-and-behavioral-problems
#14
Biyao Wang, Corinna Isensee, Andreas Becker, Janice Wong, Peter R Eastwood, Rae-Chi Huang, Kevin C Runions, Richard M Stewart, Thomas Meyer, L G Brüni, Florian D Zepf, Aribert Rothenberger
Although the prevalence rates of sleep disorders at different stages of childhood and adolescence have been well established, little is known about the developmental course of general sleep problems. This also holds true for the bidirectional relationship between sleep problems and emotional as well as behavioral difficulties. This longitudinal study investigated the general pattern and the latent trajectory classes of general sleep problems from a large community sample aged 5-14 years. In addition, this study examined the predictive value of emotional/behavioral difficulties (i...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27935730/patterns-of-pregnancy-and-postpartum-depressive-symptoms-latent-class-trajectories-and-predictors
#15
Eivor Fredriksen, Tilmann von Soest, Lars Smith, Vibeke Moe
Depressive symptoms among pregnant and postpartum women are common. However, recent studies indicate that depressive symptoms in the perinatal period do not follow a uniform course, and investigations of the heterogeneity of time courses and associated factors are needed. The aim of this study was to explore whether depressive symptoms in the perinatal period could be categorized into several distinct trajectories of symptom development among subgroups of perinatal women, and to identify predictors of these trajectory groups...
February 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27930587/body-mass-trajectories-diabetes-mellitus-and-mortality-in-a-large-cohort-of-austrian-adults
#16
Raphael Simon Peter, Ferdinand Keller, Jochen Klenk, Hans Concin, Gabriele Nagel
There are only few studies on latent trajectories of body mass index (BMI) and their association with diabetes incidence and mortality in adults.We used data of the Vorarlberg Health Monitoring & Prevention Program and included individuals (N=24,875) with BMI measurements over a 12-year period. Trajectory classes were identified using growth mixture modeling for predefined age groups (<50, 50-65, >65 years of age) and men, women separately. Poisson models were applied to estimate incidence and prevalence of diabetes for each trajectory class...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27907223/-mental-retirement-trajectories-of-work-engagement-preceding-retirement-among-older-workers
#17
Astrid de Wind, Fenna Rm Leijten, Trynke Hoekstra, Goedele A Geuskens, Alex Burdorf, Allard J van der Beek
Objectives Before actual retirement, employees may already distance themselves from work, which could be referred to as "mental retirement". However, trajectories of work motivation, ie, work engagement, have not been studied yet. The present study aimed to (i) identify different trajectories of work engagement among older workers approaching the retirement age, and (ii) examine their associations with actual retirement. Methods In total 3171 employees aged 55-62 years, who participated in the Dutch Study on Transitions in Employment, Ability and Motivation were included in this study...
January 1, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/27889856/gender-differences-in-anxiety-trajectories-from-middle-to-late-adolescence
#18
Christine McCauley Ohannessian, Stephanie Milan, Anna Vannucci
Although developmental trajectories of anxiety symptomatology have begun to be explored, most research has focused on total anxiety symptom scores during childhood and early adolescence, using racially/ethnically homogenous samples. Understanding the heterogeneous courses of anxiety disorder symptoms during middle to late adolescence has the potential to clarify developmental risk models of anxiety and to inform prevention programs. Therefore, this study specifically examined gender differences in developmental trajectories of anxiety disorder symptoms (generalized anxiety disorder, panic disorder, and social anxiety disorder) from middle to late adolescence in a diverse community sample (N = 1000; 57 % female; 65 % White), assessed annually over 2 years...
April 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27885145/trajectories-of-postpartum-depression-depression-in-italian-first-time-fathers
#19
Sara Molgora, Valentina Fenaroli, Matteo Malgaroli, Emanuela Saita
Paternal postpartum depression (PPD) has received little attention compared with maternal prenatal and postpartum depression, despite research reporting that paternal PPD concerns a substantial number of fathers. History of depression and antenatal depression have been identified as important PPD's risk factors, underlining the continuity of depressive symptoms during the transition to parenthood. However, only few studies have focused on the evolution of depressive symptoms with longitudinal research design...
November 23, 2016: American Journal of Men's Health
https://www.readbyqxmd.com/read/27859946/impact-of-childhood-asthma-on-growth-trajectories-in-early-adolescence-findings-from-the-childhood-asthma-prevention-study-caps
#20
Maria Movin, Frances L Garden, Jennifer L P Protudjer, Vilhelmina Ullemar, Frida Svensdotter, David Andersson, Andreas Kruse, Chris T Cowell, Brett G Toelle, Guy B Marks, Catarina Almqvist
BACKGROUND AND OBJECTIVE: Understanding the associations between childhood asthma and growth in early adolescence by accounting for the heterogeneity of growth during puberty has been largely unexplored. The objective was to identify sex-specific classes of growth trajectories during early adolescence, using a method which takes the heterogeneity of growth into account and to evaluate the association between childhood asthma and different classes of growth trajectories in adolescence...
April 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
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