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https://www.readbyqxmd.com/read/29767393/small-bowel-capsule-endoscopy-in-clinical-practice-has-anything-changed-over-13-years
#1
Marco Soncini, Carlo Maria Girelli, Roberto de Franchis, Emanuele Rondonotti
BACKGROUND: In Lombardia, one of the 20 Italian administrative Regions, small-bowel capsule endoscopy (SBCE) was introduced in 2001. In January 2011, the Regional Health Authorities established a reimbursement for outpatient SBCE. AIM: To prospectively record data on SBCE between 2011-2013 and compare them to similar data retrospectively collected from the same geographical area (covering the period 2001-2008) and published in 2008. METHODS: Consecutive SBCEs performed between January 2011 and December 2013 in Lombardia were prospectively collected...
May 16, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29759099/procedural-sedation-by-advanced-care-paramedics-for-emergency-gastrointestinal-endoscopy
#2
Hana M Wiemer, Michael B Butler, Patrick C Froese, Allan Lapierre, Chris Carriere, Glen R Etsell, Dana Farina, Jennifer Jones, Jock Murray, Samuel G Campbell
CLINICIAN'S CAPSULE What is known about the topic? Advanced care paramedics (ACPs) in our emergency department (ED) successfully perform procedural sedation and analgesia (PSA) for several procedures, including orthopedic manipulations. What did this study ask? How does the novel practice of ACP-led ED PSA for upper gastrointestinal (UGI) endoscopy compare to that for orthopedic procedures? What did this study find? Adverse events occurred more frequently during UGI endoscopy sedations than orthopedic sedations (41...
May 15, 2018: CJEM
https://www.readbyqxmd.com/read/29756020/multicenter-prospective-evaluation-of-the-express-view-reading-mode-for-small-bowel-capsule-endoscopy-studies
#3
Jean-Christophe Saurin, Philippe Jacob, Laurent Heyries, Christian Pesanti, Franck Cholet, Isaac Fassler, James Boulant, Slim Bramli, Antoin De Leusse, Gabriel Rahmi
Background:  Reducing the reading time of capsule endoscopy films is of high priority for gastroenterologists. We report a prospective multicenter evaluation of an "express view" reading mode (Intromedic capsule system). Methods:  Eighty-three patients with obscure gastrointestinal bleeding were prospectively included in 10 centers. All patients underwent small-bowel capsule endoscopy (Intromedic, Seoul, Republic of Korea). Films were read in standard mode, then a second reading was performed in express view mode at a second center...
May 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29754836/misoprostol-for-small-bowel-ulcers-in-patients-with-obscure-bleeding-taking-aspirin-and-non-steroidal-anti-inflammatory-drugs-masters-a-randomised-double-blind-placebo-controlled-phase-3-trial
#4
Ali S Taha, Caroline McCloskey, Paula McSkimming, Alex McConnachie
BACKGROUND: The incidence of obscure gastrointestinal bleeding, which originates from the small bowel and is mainly associated with the use of aspirin and non-steroidal anti-inflammatory drugs (NSAIDs), is rising. We assessed the efficacy and safety of misoprostol for the treatment of small bowel ulcers and erosions in patients taking low-dose aspirin or NSAIDs with obscure gastrointestinal bleeding. METHODS: In this randomised, double-blind, placebo-controlled, phase 3 trial, we recruited patients (aged ≥18 years) with small bowel ulcers who were taking low-dose aspirin, NSAIDs, or both for a minimum of 4 weeks, at University Hospital Crosshouse (Kilmarnock, UK)...
May 10, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29754035/the-elusive-small-bowel-adenocarcinoma-in-the-terminal-ileum-a-case-report
#5
Joyce Lok Gee Ma, Paul Norman Strauss
INTRODUCTION: Small bowel malignancies are rare and often present with non-specific symptoms. Because of this, diagnosis of small bowel malignancies is often missed. PRESENTATION OF CASE: 71-year-old male presented with a four-week history of right iliac fossa pain and loss of weight. Laboratory tests showed a raised C-reactive protein, but all other pathology results and tumour-associated antigens were normal. Computed tomography (CT) of the abdomen demonstrated an inflammatory mass extending laterally into the pelvic wall...
April 27, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29735872/a-steroid-resistant-cryptogenic-multifocal-ulcerous-stenosing-enteritis
#6
Y Yang, L Zhao, Y Zhang
Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare chronic and recurrent disease with unknown etiology. It characterized by shallow ulcers, submucosa thickness, and no signs of systematic inflammation. Now, steroids are the principle therapy for CMSUE. However, still, there were few patients who did not response to it. Here, we present a young woman who diagnosed with CMUSE. She underwent a surgery because of capsule endoscopy retention. After relapse, she had received budesonide and methylprednisolone separately while both of them did not stop her disease...
May 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29732361/nonsteroidal-anti-inflammatory-drugs-induced-diaphragm-disease-a-report-of-3-cases-and-literature-review
#7
Chun-Seok Yang, Ji Y Park, Hye Ryeon Choi, Daedong Kim
Multiple strictures of small bowel induced by nonsteroidal anti-inflammatory drugs (NSAIDs), were known as diaphragm disease. The purpose of these case reports is to present 3 cases of diaphragm disease of small bowel and summarize the clinical features of this disease entity. A 34-year-old man, a 63-year-old man, and a 66-year-old woman were admitted to Daegu Catholic University Medical Center because of recurrent intestinal obstructions. Two of these patients had taken heavy NSAIDs use. Capsule endoscopy was performed in all cases and the all capsules were retained by circumferential strictures of the ileum...
May 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29729056/a-case-of-small-intestinal-bacterial-overgrowth-performed-capsule-and-double-balloon-endoscopy
#8
Ichiro Otani, Shiro Oka, Shinji Tanaka
A 67-year old woman who had received treatment with prednisolone for systemic scleroderma visited our hospital. She complained of mild abdominal pain, bloating, anorexia, watery stools (approximately three times a day). Abdominal computed tomography showed high contrast appearance and thickening of the entire small intestinal wall as well as accumulation of intestinal fluid with no mechanical obstruction (Figure 1). Capsule endoscopy (Figure 2a) and antegrade double-balloon endoscopy (Figure 2b) revealed retention of cloudy intestinal fluid throughout the entire small intestine with reddish and edematous mucosa...
May 5, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29722829/fecal-calprotectin-as-a-selection-tool-for-small-bowel-capsule-endoscopy-in-suspected-crohn-s-disease
#9
Sara Monteiro, Mara Barbosa, Tiago Cúrdia Gonçalves, Pedro Boal Carvalho, Maria João Moreira, Bruno Rosa, José Cotter
Background: Small bowel capsule endoscopy (SBCE) is a firstline examination in patients with suspected Crohn's disease (CD) after negative ileocolonoscopy. Fecal calprotectin (FC) is a noninvasive marker of intestinal inflammation. The aim of this study was to evaluate the predictive value of FC in inflammatory activity detected by SBCE in patients with suspected CD. Methods: This is a retrospective study including patients who underwent SBCE for suspected CD between March 2015 and October 2016...
May 2, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29720856/%C3%AE-on-invasive-screening-for-esophageal-varices-in-patients-with-liver-cirrhosis
#10
REVIEW
Andreas Karatzas, Christos Konstantakis, Ioanna Aggeletopoulou, Christina Kalogeropoulou, Konstantinos Thomopoulos, Christos Triantos
Esophageal varices are one of the main complications of liver cirrhosis. Upper gastrointestinal endoscopy is the gold standard for the detection of esophageal varices. Many less invasive methods for screening of varices have been investigated and the most recent Baveno VI guidelines suggest that endoscopy is not necessary in patients with liver stiffness <20 kPa and platelets >150,000/μL. A critical review of the literature was performed concerning non-invasive or minimally invasive methods of screening for esophageal varices...
May 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29718414/a-simple-1-day-colon-capsule-endoscopy-procedure-demonstrated-to-be-a-highly-acceptable-monitoring-tool-for-ulcerative-colitis
#11
Shinji Okabayashi, Taku Kobayashi, Masaru Nakano, Takahiko Toyonaga, Ryo Ozaki, Maria Carla Tablante, Satoshi Kuronuma, Osamu Takeuchi, Toshifumi Hibi
Background: Second-generation colon capsule endoscopy (CCE-2) has been reported as a potential tool for monitoring ulcerative colitis (UC). However, its excretion rate is still unsatisfactory, and the bowel preparation regimen is not well tolerated. Furthermore, a standard bowel preparation regimen validated for UC has not been established. The aim of this study was to develop a simple 1-day CCE-2 procedure while evaluating its excretion rate and acceptability in UC. Factors associated with the colonic transit time and acceptability of CCE-2 were evaluated...
April 30, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29717351/capsule-endoscopy-vs-colonoscopy-vs-histopathology-in-colorectal-cancer-screening-matched-analyses-of-polyp-size-morphology-and-location-estimates
#12
Victoria Blanes-Vidal, Esmaeil S Nadimi, Maria Magdalena Buijs, Gunnar Baatrup
PURPOSE: Colon capsule endoscopy (CCE) is considered a potential alternative to optical colonoscopy (OC) for colorectal cancer screening. However, the accuracy of CCE in polyp size and morphology estimation is unknown. METHODS: A fully paired study was performed (2015-2016), where 255 participants from the Danish national screening program had CCE, OC, and histopathology (HP) of all detected polyps. We developed a new algorithm to match CCE and OC polyps, based on objective measures of similarity between polyps...
May 1, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29713191/endoscopic-comparison-of-gastroduodenal-injury-with-over-the-counter-doses-of-new-fast-dissolving-ibuprofen-and-paracetamol-formulations-a-randomized-placebo-controlled-4-way-crossover-clinical-trial
#13
Frank L Lanza, Agron Collaku, Dongzhou J Liu
Background: While gastrointestinal (GI) effects of standard ibuprofen and N-acetyl-p-aminophenol (APAP) have been reported, upper GI injury following treatment with fast-dissolving (FD) formulations of these analgesics has not been investigated. We evaluated upper GI effects of over-the-counter doses of 2 FD ibuprofen products and 1 FD-APAP product. Methods: In a randomized, placebo-controlled, endoscopist-blinded, 4-way crossover study, 28 healthy subjects received FD ibuprofen 2×200 mg liquid capsules 3 times daily (TID), ibuprofen 2×200 mg tablets TID, FD-APAP 2×500 mg tablets 4 times daily (QID), and placebo 2×500 mg tablets QID for 7 days...
2018: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/29707077/suspected-blood-indicator-to-identify-active-gastrointestinal-bleeding-a-prospective-validation
#14
Samuel Han, Julien Fahed, David R Cave
Background: The suspected blood indicator (SBI) function in the RAPID Reader v8.3 program was designed to quickly identify the presence of blood in video capsule endoscopy. While previous retrospective studies have shown that the SBI function was accurate in detecting the presence of active bleeding in the small bowel, its specificity and sensitivity were poor. Methods: An initial retrospective review (phase 1) compared 115 patients with active gastrointestinal bleeding seen on video capsule endoscopy (VCE) to 115 patients with no active bleeding seen on VCE to produce a highly accurate algorithm...
April 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29698967/motorized-spiral-enteroscopy-for-occult-bleeding
#15
Laura Mans, Marianna Arvanitakis, Horst Neuhaus, Jacques Devière
Small-bowel disorders remain a diagnostic and therapeutic challenge due to intestinal length. Their management was revolutionized by the emergence of deep enteroscopy. In comparison with video capsule endoscopy, deep enteroscopy allows diagnostic and therapeutic interventions. Spiral enteroscopy (Spirus Medical Endo-Ease Overtube) achieves progression by gentle push and manual clockwise rotation inducing pleating of the small bowel on the endoscope. It has the advantage of shorter examination time and more stability during withdrawal but requires two operators...
April 26, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29698945/comparison-of-small-bowel-lesions-using-capsule-endoscopy-in-ulcerative-colitis-and-crohn-s-disease-a-single-center-retrospective-analysis
#16
Kazeo Ninomiya, Takashi Hisabe, Yuki Okado, Yasumichi Takada, Rino Yamaoka, Yuho Sato, Masahiro Kishi, Noritaka Takatsu, Toshiyuki Matsui, Toshiharu Ueki, Kenshi Yao, Fumihito Hirai
BACKGROUND: Capsule endoscopy (CE) has allowed the characterization of small bowel lesions. However, small bowel lesions in ulcerative colitis (UC) have not been elucidated and no studies have compared between UC and Crohn's disease (CD). AIM: The objective of this study was to investigate the small bowel lesions in UC, and to characterize UC lesions by comparison with CD. METHODS: Subjects comprised 54 UC patients and 39 CD patients who underwent CE...
April 26, 2018: Digestion
https://www.readbyqxmd.com/read/29697457/association-of-clinical-and-inflammatory-markers-with-small-bowel-capsule-endoscopy-findings-in-crohn-s-disease
#17
Ioannis V Mitselos, Konstantinos H Katsanos, Athina Tatsioni, Alexandros Skamnelos, Rami Eliakim, Epameinondas V Tsianos, Dimitrios K Christodoulou
BACKGROUND: Mucosal healing is an established treatment endpoint in Crohn's disease (CD). Still, clinical indices and inflammatory markers are used widely in CD surveillance. AIM: The aim of this study was to investigate the diagnostic performance as well as the relationship of C-reactive protein (CRP) and Crohn's Disease Activity Index (CDAI) with small bowel capsule endoscopy's (SBCE) inflammation scoring index, the Lewis Score (LS). PATIENTS AND METHODS: CDAI, CRP, and SBCE findings of 30 CD patients with isolated small bowel disease were retrieved from our academic institution patient records and were analyzed statistically...
April 24, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29696804/rebleeding-rate-and-risk-factors-in-non-steroidal-anti-inflammatory-drug-induced-enteropathy
#18
Junseok Park, Seong Ran Jeon, Jin-Oh Kim, Hyun Gun Kim, Tae Hee Lee, Jun-Hyung Cho, Bong Min Ko, Joon Seong Lee, Moon Sung Lee
OBJECTIVE: Limited evidence is available regarding rebleeding due to non-steroidal anti-inflammatory drug (NSAID)-induced enteropathy. Previous studies have primarily analyzed endoscopic findings. Therefore, there is a need to evaluate the clinical implications for patients. This study aimed to evaluate the rebleeding rate and its related risk factors in patients with NSAID-induced enteropathy. METHODS: Of 402 patients with obscure gastrointestinal bleeding who were evaluated with capsule endoscopy, 49 were diagnosed with NSAID-induced enteropathy...
April 25, 2018: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29691276/asia-pacific-working-group-consensus-on-non-variceal-upper-gastrointestinal-bleeding-an-update-2018
#19
Joseph Jy Sung, Philip Cy Chiu, Francis K L Chan, James Yw Lau, Khean-Lee Goh, Lawrence Hy Ho, Hwoon-Young Jung, Jose D Sollano, Takuji Gotoda, Nageshwar Reddy, Rajvinder Singh, Kentaro Sugano, Kai-Chun Wu, Chun-Yin Wu, David J Bjorkman, Dennis M Jensen, Ernst J Kuipers, Angel Lanas
Non-variceal upper gastrointestinal bleeding remains an important emergency condition, leading to significant morbidity and mortality. As endoscopic therapy is the 'gold standard' of management, treatment of these patients can be considered in three stages: pre-endoscopic treatment, endoscopic haemostasis and post-endoscopic management. Since publication of the Asia-Pacific consensus on non-variceal upper gastrointestinal bleeding (NVUGIB) 7 years ago, there have been significant advancements in the clinical management of patients in all three stages...
April 24, 2018: Gut
https://www.readbyqxmd.com/read/29686230/nomogram-based-prediction-of-rebleeding-in-small-bowel-bleeding-patients-the-prsbb-score
#20
Genta Uchida, Yoshiki Hirooka, Masanao Nakamura, Osamu Watanabe, Takeshi Yamamura, Masanobu Matsushita, Hiroki Suhara, Takuya Ishikawa, Kazuhiro Furukawa, Kohei Funasaka, Eizaburo Ohno, Hiroki Kawashima, Ryoji Miyahara, Hidemi Goto
Small bowel capsule endoscopy (SBCE) and balloon-assisted endoscopy (BAE) have revolutionized the diagnosis and treatment of small bowel bleeding (SBB), allowing access to the small bowel and identification of specific bleeding lesions. However, some patients experience rebleeding after small bowel investigation, and there are no definitive algorithms for determining the most appropriate follow-up strategy in SBB patients. We developed and validated a nomogram that can predict rebleeding risk and be used to develop a risk-stratified follow-up strategy in SBB patients...
April 23, 2018: Scientific Reports
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