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https://www.readbyqxmd.com/read/27908521/neoplastic-diseases-of-the-small-bowel
#1
REVIEW
Emanuele Rondonotti, Anastasios Koulaouzidis, Diana E Yung, Surekha N Reddy, Julius Georgiou, Marco Pennazio
The incidence of small bowel tumors is increasing over time. Until recently, their diagnosis was delayed and it was often reached only at the time of surgery. New diagnostic tools, such as capsule endoscopy, device-assisted enteroscopy, and dedicated small bowel cross-sectional imaging techniques, have been introduced recently in clinical practice. The combination of these tools allows medical practitioners to detect small bowel tumors at an early stage and to reach a definite diagnosis before surgery, thus enabling minimally invasive treatments...
January 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/27908519/inflammatory-disorders-of-the-small-bowel
#2
REVIEW
Jonathan A Leighton, Shabana F Pasha
The most common small bowel inflammatory disorders include Crohn disease, nonsteroidal antiinflammatory drug (NSAID) enteropathy, and celiac disease. Capsule endoscopy, computed tomography enterography, and magnetic resonance enterography have a complementary role in the diagnosis of Crohn disease and evaluation of patients with established Crohn disease. The higher risk of capsule retention with known Crohn disease and NSAID enteropathy can be minimized by cross-sectional imaging or the patency capsule. The main role of deep enteroscopy is tissue diagnosis, endoscopic management of small bowel lesions and strictures, and retrieval of retained capsules...
January 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/27908517/small-bowel-capsule-endoscopy-normal-findings-and-normal-variants-of-the-small-bowel
#3
REVIEW
Marco Pennazio, Emanuele Rondonotti, Anastasios Koulaouzidis
Small bowel capsule endoscopy (SBCE) remains the gold standard for practice for the diagnosis of small bowel disorders. A rather challenging task, for those who start to use this diagnostic modality, is the recognition of the typical anatomic landmarks and the distinction of normal small bowel anatomy from abnormal findings. The reader of SBCE images may also often encounter unusual views of the normal anatomy as well as various artifacts that need to be distinguished from pathologic findings. Experience gained through standard endoscopy is invaluable to the interpretation of capsule examinations; however, formalized training and credentialing in reading competency are essential...
January 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/27908516/small-bowel-bleeding-updated-algorithm-and-outcomes
#4
REVIEW
Lauren B Gerson
Patients previously classified with "obscure gastrointestinal hemorrhage" should now be classified as "suspected small bowel bleeding" according to the 2015 American College of Gastroenterology guidelines. This article provides algorithms for how to manage patients with suspected small bowel bleeding, including utilization of second-look endoscopy and/or colonoscopy, video capsule endoscopy, computed tomographic enterography, magnetic resonance enterography, angiography, and deep enteroscopy.
January 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/27908514/video-capsule-endoscopy-technology-reading-and-troubleshooting
#5
REVIEW
Jodie A Barkin, Jamie S Barkin
Video capsule endoscopy (VCE) has completed the endoscopic visualization of the entire luminal gastrointestinal tract. VCE can be performed in inpatients and outpatients, requires appropriate bowel preparation before the study, and can be administered via oral swallowing or endoscopic device placement into the small bowel based on outlined patient-dependent factors. Current commercially available VCE systems were reviewed and compared for individual features and attributes. This article focuses on preparation for VCE, currently available VCE technology, how to read a VCE study, and risks and contraindications to VCE...
January 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/27908270/the-importance-of-wireless-capsule-endoscopy-for-research-into-the-intestinal-absorption-window-of-5-aminosalicylic-acid-in-experimental-pigs
#6
Jaroslav Kvetina, Ilja Tacheci, Milan Nobilis, Marcela Kopacova, Martin Kunes, Jan Bures
BACKGROUND: Absorption windows in particular segments of the small intestine can contribute to the development of orally administered drug formulations and can limit the bioavailability of released compounds. OBJECTIVE: The aim of this study was to evaluate use of wireless capsule enteroscopy regarding the disintegration kinetic process of tablets in the small intestine and its comparison with the levels of the model drug (5-aminosalicylic acid; 5-ASA), and its majority metabolite (N-acetyl-5-aminosalicylic acid; N-acetyl-5-ASA) in blood plasma...
December 1, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27895862/cutaneous-angiosarcoma-metastatic-to-small-bowel-with-nodal-involvement
#7
Vidya A Fleetwood, Jamie C Harris, Minh B Luu
A 77-year-old male with a history of metastatic scalp angiosarcoma presented with intractable gastrointestinal bleeding from a jejunal mass detected on capsule endoscopy. He underwent laparoscopic-assisted resection of the mass. Intraoperatively, an isolated small bowel mass with bulky lymphadenopathy was seen and resected en bloc. Pathology showed a 6.8cm high-grade metastatic angiosarcoma with nodal involvement and negative margins. Angiosarcoma is a sarcoma with a grim prognosis. The incidence is 2% of all soft tissue sarcomas; cutaneous lesions comprise 27% of manifestations and usually appear on head and neck...
2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/27895392/determination-of-the-adequate-dosage-of-rebamipide-a-gastric-mucoprotective-drug-to-prevent-low-dose-aspirin-induced-gastrointestinal-mucosal-injury
#8
Kazuhiro Ota, Toshihisa Takeuchi, Sadaharu Nouda, Haruhiko Ozaki, Shinpei Kawaguchi, Yoshiaki Takahashi, Satoshi Harada, Shoko Edogawa, Yuichi Kojima, Takanori Kuramoto, Kazuhide Higuchi
Small intestinal mucosal injury caused by low-dose aspirin is a common cause of obscure gastrointestinal bleeding. We aimed to investigate the protective effects and optimal dose of rebamipide for low-dose aspirin-induced gastrointestinal mucosal injury. In this prospective randomized trial, 45 healthy volunteers (aged 20-65 years) were included and divided into three groups. The groups received enteric-coated aspirin 100 mg (low-dose aspirin) plus omeprazole 10 mg (Group A: proton pump inhibitor group), low-dose aspirin plus rebamipide 300 mg (Group B: standard-dose group), or low-dose aspirin plus rebamipide 900 mg (Group C: high-dose group)...
November 2016: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/27893668/outcome-of-endoscopy-negative-iron-deficiency-anemia-in-patients-above-65-a-longitudinal-multicenter-cohort
#9
Raphaël Clere-Jehl, Erik Sauleau, Stefan Ciuca, Mickael Schaeffer, Amanda Lopes, Bernard Goichot, Thomas Vogel, Georges Kaltenbach, Eric Bouvard, Jean-Louis Pasquali, Daniel Sereni, Emmanuel Andres, Anne Bourgarit
After the age of 65 years, iron deficiency anemia (IDA) requires the elimination of digestive neoplasia and is explored with upper and lower gastrointestinal (GI) endoscopy. However, such explorations are negative in 14% to 37% of patients. To further evaluate this issue, we evaluated the outcomes of patients aged over 65 years with endoscopy-negative IDA.We retrospectively analyzed the outcomes of in-patients over the age of 65 years with IDA (hemoglobin <12 g/dL and ferritin <70 μg/L) who had negative complete upper and lower GI endoscopies in 7 tertiary medical hospitals...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27889847/diagnostic-value-of-small-bowel-capsule-endoscopy-in-isolated-ileitis-a-capentry-study
#10
Hyun Seok Lee, Yun Jeong Lim, Ki Nam Shim, Chang Mo Moon, Hyun Joo Song, Jin Oh Kim, Seong Ran Jeon, Dae Young Jung, Ji Hyun Kim, Kyeong Ok Kim, Bo-In Lee
BACKGROUND: Capsule endoscopy (CE) has proven to be highly effective at detecting small bowel lesions, but studies regarding the diagnostic impact of CE on ileitis are rare. AIMS: We evaluated the diagnostic value of small bowel CE for isolated ileitis observed during ileocolonoscopy. METHODS: The CE results in 137 patients initially diagnosed with ileitis without colonic mucosal abnormalities on ileocolonoscopy at one of eight tertiary referral centers between October 2002 and June 2015 were retrospectively analyzed...
November 26, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27889734/retained-capsule-endoscope
#11
Jayalaxmi S Aihole, G S Vishnumurthy, M Narendra Babu
BACKGROUND: Capsule endoscopy was invented to visualize the entire small intestine in a non- invasive manner in adults. CASE CHARACTERISTICS: 1 y, 9 mo-old boy presented with generalized edema for last 3 months. His routine investigations, including the upper gastrointestinal endoscopy, colonoscopy, and contrast enhanced computed tomography scan (CECT) were normal. In view of clinical suspicion of protein losing enteropathy, we planned capsule endoscopy. OBSERVATION: The capsule was not passed even after 3 weeks...
November 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27888219/long-term-intestinal-bleeding-in-a-child-a-rare-case-of-heterotopic-gastric-mucosa-in-the-jejunum
#12
Stella Leng, Marco Ghionzoli, Chiara Caporalini, Anna Maria Buccoliero
We report a rare case of heterotopic gastric mucosa presenting in a jejunal polyp of a 9-year-old girl, diagnosed with capsule endoscopy and laparoscopic exploration, after a 15-month history of lower gastrointestinal bleeding and anaemia. During surgery, the jejunal segment containing the polyp was resected and pathological examination revealed a polyp with gastric heterotopia. Heterotopic gastric mucosa is a rare pathology characterised by the presence of gastric mucosa outside of the stomach. Heterotopic gastric mucosa usually occurs in the oesophagus, duodenum, Meckel's diverticulum and enteric duplication cysts...
November 25, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27867950/review-capsule-colonoscopy-a-concise-clinical-overview-of-current-status
#13
REVIEW
Diana E Yung, Emanuele Rondonotti, Anastasios Koulaouzidis
The colon capsule endoscopy (CCE) was first introduced in 2007. Currently, the main clinical indications for CCE are completion of incomplete colonoscopy, polyp detection and investigation of inflammatory bowel disease (IBD). Although conventional colonoscopy is the gold standard in bowel cancer screening, incomplete colonoscopy remains a problem as lesions are missed. CCE compares favourably to computer tomography colonography (CTC) in adenoma detection and has therefore been proposed as a method for completing colonoscopy...
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27855797/video-capsule-endoscopy-for-triage-of-patients-with-acute-upper-gi-hemorrhage-is-seeing-believing
#14
EDITORIAL
Amir Klein, Ian M Gralnek
No abstract text is available yet for this article.
December 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27852081/small-bowel-perforation-caused-by-advance-capsule-endoscopy-delivery-device
#15
Marion Simon, Sandrine Barge, Florence Jeune, Helene Corte, Pierre Cattan, Jean-Marc Gornet
No abstract text is available yet for this article.
January 2016: Endoscopy
https://www.readbyqxmd.com/read/27842442/the-validity-of-suspected-blood-indicator-software-in-capsule-endoscopy-a-systematic-review-and-meta-analysis
#16
Diana E Yung, Catherine Sykes, Anastasios Koulaouzidis
Software tools have been developed as capsule endoscopy (CE) reading aids. The suspected blood indicator (SBI) tags possible areas of haemorrhage in the gastrointestinal (GI) tract. This meta-analysis aims to investigate the diagnostic accuracy of SBI in CE. Areas covered: A systematic literature search was conducted for studies on the use of SBI in CE. Sensitivity, specificity and diagnostic odds ratio (DOR) of SBI in diagnosing GI bleeding was evaluated. 2040 patients from 16 studies underwent 2049 CE examinations...
November 21, 2016: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27829601/whipple-s-disease-diagnosed-using-electron-microscopy-and-polymerase-chain-reaction
#17
Tomohiro Nagasue, Koichi Kurahara, Hiroki Yaita, Takahide Tanaka, Yumi Oshiro, Nobuaki Kuno, Akira Harada, Masashi Kameda, Kazuhide Iwasaki, Yutaka Tsutsumi
A 50-year-old man presented with bloody diarrhea and 25-kg weight loss over 3 months. Upper and lower endoscopy showed diffuse shaggy white villi in the duodenum and terminal ileum. In addition, capsule endoscopy and double-balloon enteroscopy revealed shaggy white villi in the entire small intestine. Histological examination of biopsy specimens found the lamina propria of the duodenal and intestinal mucosa to be densely infiltrated by rich foamy macrophages that were periodic acid-Schiff-positive. Electron microscopy showed numerous bacilli in the lamina propria...
2016: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/27826572/capsule-endoscopy-of-the-small-bowel
#18
REVIEW
Mark E McAlindon, Hey-Long Ching, Diana Yung, Reena Sidhu, Anastasios Koulaouzidis
Capsule endoscopy (CE) is a first line small bowel investigative modality which provides more sensitive mucosal imaging than comparators. It is a non-invasive, non-irradiating tool well tolerated by patients. The risk of retention of the capsule can be minimised by ensuring luminal patency using the Agile patency device. Research continues into how to minimise missed pathology and variability in the identification of pathology or interpretation of images. The consensus is that bowel preparation using laxatives improves visibility and diagnostic yield...
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27821032/small-bowel-capsule-endoscopy-for-the-investigation-of-obscure-gastrointestinal-bleeding-when-we-should-do-it-and-what-should-we-expect
#19
REVIEW
N Viazis, J Anastasiou, D G Karamanolis
Obscure gastrointestinal bleeding is defined as bleeding of unknown origin that persists or recurs (i.e. recurrent or persistent iron deficiency anemia, fecal occult blood test positivity or visible bleeding) after a negative initial workout that necessarily includes gastroscopy and colonoscopy. In clinical practice, small bowel capsule endoscopy is recommended as a third stage examination in these patients, since it is a simple, safe, non-invasive and reliable test. To date there are three available small bowel capsule systems that have gained FDA approval and their diagnostic yield has shown to be superior to other diagnostic modalities for the investigation of the small bowel in patients with obscure gastrointestinal bleeding...
July 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/27818583/potential-of-hybrid-adaptive-filtering-in-inflammatory-lesion-detection-from-capsule-endoscopy-images
#20
REVIEW
Vasileios S Charisis, Leontios J Hadjileontiadis
A new feature extraction technique for the detection of lesions created from mucosal inflammations in Crohn's disease, based on wireless capsule endoscopy (WCE) images processing is presented here. More specifically, a novel filtering process, namely Hybrid Adaptive Filtering (HAF), was developed for efficient extraction of lesion-related structural/textural characteristics from WCE images, by employing Genetic Algorithms to the Curvelet-based representation of images. Additionally, Differential Lacunarity (DLac) analysis was applied for feature extraction from the HAF-filtered images...
October 21, 2016: World Journal of Gastroenterology: WJG
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