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https://www.readbyqxmd.com/read/28524600/validation-of-smartpill-%C3%A2-wireless-motility-capsule-for-gastrointestinal-transit-time-intra-subject-variability-software-accuracy-and-comparison-with-video-capsule-endoscopy
#1
H O Diaz Tartera, D-L Webb, A Kh Al-Saffar, M A Halim, G Lindberg, P Sangfelt, P M Hellström
BACKGROUND: There is interest in ultimately combining endoscopy and motility assessments. Gastric emptying (GET), small bowel (SBTT), colon (CTT) and whole gut transit (WGTT) times are conveniently obtained by SmartPill(®) wireless motility capsule (WMC) that records luminal pH, temperature and pressure. Reproducibility within same subjects and accuracy of software derived times (MotiliGI(®) ) were investigated for diagnostic application. GET and SBTT were separately measured using video capsule endoscopy (VCE)...
May 19, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28512034/diagnostic-yield-of-capsule-endoscopy-versus-magnetic-resonance-enterography-and-small-bowel-contrast-ultrasound-in-the-evaluation-of-small-bowel-crohn-s-disease-systematic-review-and-meta-analysis
#2
REVIEW
Uri Kopylov, Diana E Yung, Tal Engel, Sanju Vijayan, Ofir Har-Noy, Lior Katz, Salvatore Oliva, Tomer Avni, Robert Battat, Rami Eliakim, Shomron Ben-Horin, Anastasios Koulaouzidis
BACKGROUND AND AIMS: Capsule endoscopy (CE), magnetic resonance enterography (MRE) and small bowel (SB) intestinal contrast ultrasound (SICUS) are the modalities of choice for SB evaluation. This study aimed to compare the diagnostic yield (DY) of CE to MRE and SICUS in detection and monitoring of SB CD through meta-analysis of the available literature. METHODS: We performed a systematic literature search for trials comparing the accuracy of CE, MRE and SICUS for detection of active SB inflammation in patients with suspected and/or established CD...
April 27, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28506799/diffusion-weighted-imaging-in-quiescent-crohn-s-disease-correlation-with-inflammatory-biomarkers-and-video-capsule-endoscopy
#3
E Klang, U Kopylov, R Eliakim, N Rozendorn, D Yablecovitch, A Lahat, S Ben-Horin, M M Amitai
AIM: To investigate the role of restricted diffusion in quiescent Crohn's disease (CD) patients and its association with inflammatory biomarkers and endoscopic disease. MATERIAL AND METHODS: Fifty-two quiescent CD patients prospectively underwent magnetic resonance enterography (MRE) and video capsule endoscopy (VCE) and were tested for the inflammatory biomarkers, faecal calprotectin (FCP) and C-reactive protein (CRP). Restricted diffusion in the distal ileum was qualitatively (absence/presence) and quantitatively (apparent diffusion coefficient [ADC]) assessed by two readers...
May 13, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28506132/lanreotide-in-the-management-of-small-bowel-angioectasias-seven-year-data-from-a-tertiary-centre
#4
S Chetcuti Zammit, D S Sanders, R Sidhu
BACKGROUND AND AIMS: Haemorrhage from small bowel angioectasias (SBAs) can be debilitating to patients who are very often elderly and have multiple comorbidities. Our aim was to assess the use of lanreotide in addition to endotherapy in patients with SBAs. METHOD: Patients with SBAs on capsule endoscopy (CE) who received lanreotide injections from January 2010 to till the present day at the Royal Hallamshire Hospital in Sheffield were included. Baseline demographics were recorded...
May 16, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28489838/-diagnostic-and-therapeutic-approach-to-small-bowel-disorders-through-capsule-endoscopy-and-double-balloon-endoscopy
#5
Federico De Simone, Pablo Machado, Edson Guzmán Calderon
Many small bowel disorders represent a great challenge for gastroenterologists and endoscopists due to the very low rates of success showed by the different agnosis techniques. The advent of the capsule endoscopy and double-balloon endoscopy has allowed a total, secure and efficient examination of the small bowel, which represents a real impact in diagnosis, treatment, and prognosis of our patients. The capsule endoscopy is a safe, minimally invasive procedure, which does not need sedation, does not cause pain, and allows the observation of the totality of the small bowel...
January 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28481007/the-influence-of-cyp2c19-polymorphisms-on-exacerbating-effect-of-rabeprazole-in-celecoxib-induced-small-bowel-injury
#6
Y Nuki, J Umeno, E Washio, Y Maehata, A Hirano, M Miyazaki, H Kobayashi, T Kitazono, T Matsumoto, M Esaki
BACKGROUND: Simultaneous use of proton pump inhibitors (PPIs) has been shown to increase the risk of nonsteroidal anti-inflammatory drug (NSAID)-induced small bowel injury. AIM: To investigate whether polymorphisms of the cytochrome P450 2C19 gene (CYP2C19), encoding a key metabolising enzyme for PPIs, are associated with small bowel injury induced by celecoxib in combination with the PPI rabeprazole. METHODS: Study participants included 55 healthy Japanese volunteers, who participated in the PPI-NSAID Kyushu University Study using video capsule endoscopy...
May 8, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28475050/development-of-a-mechanical-scanning-device-with-high-frequency-ultrasound-transducer-for-ultrasonic-capsule-endoscopy
#7
Xingying Wang, Vipin Seetohul, Ruimin Chen, Ming Qian, Congzhi Wang, Zhihong Huang, Qifa Zhou, Hairong Zheng, Sandy Cochran, Weibao Qiu
Wireless capsule endoscopy has opened a new era by enabling remote diagnostic assessment of the gastrointestinal (GI) tract in a painless procedure. Video capsule endoscopy (VCE) is currently commercially available worldwide. However, it is limited to visualization of superficial tissue. Ultrasound (US) imaging is a complementary solution as it is capable of acquiring transmural information from the tissue wall. This paper presents a mechanical scanning device incorporating a high-frequency transducer specifically as a proof of concept for ultrasound capsule endoscopy (USCE), providing information that may usefully assist future research...
May 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28463855/noncardiac-chest-pain-diagnosis-and-management
#8
Takahisa Yamasaki, Ronnie Fass
PURPOSE OF REVIEW: Noncardiac chest pain (NCCP) has been defined as recurrent chest pain that is indistinguishable from ischemic heart pain after excluding a cardiac cause. NCCP is a common and highly challenging clinical problem in Gastrointestinal practice that requires targeted diagnostic assessment to identify the underlying cause of the symptoms. Treatment is tailored according to the cause of NCCP: gastroesophageal reflux disease (GERD), esophageal dysmotility or functional chest pain...
May 1, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28459696/wireless-capsule-gastrointestinal-endoscopy-direction-of-arrival-estimation-based-localization-survey
#9
Nilanjan Dey, Amira S Ashour, Fuquian Shi, Robert Simon Sherratt
One of the significant challenges in Capsule Endoscopy (CE) is to precisely determine the pathologies location. The localization process is primarily estimated using the received signal strength from sensors in the capsule system through its movement in the gastrointestinal (GI) tract. Consequently, the wireless capsule endoscope (WCE) system requires improvement to handle the lack of the capsule instantaneous localization information and to solve the relatively low transmission data rate challenges. Furthermore, the association between the capsule's transmitter position, capsule location, signal reduction and the capsule direction should be assessed...
April 25, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28450815/evidence-based-guide-on-capsule-endoscopy-for-small-bowel-bleeding
#10
Shabana F Pasha, Jonathan A Leighton
Capsule endoscopy is the diagnostic test of choice for the evaluation of overt and occult small bowel bleeding. Its yield is higher in patients presenting with overt bleeding. The yield is also improved if the capsule is performed soon after the presentation of bleeding. Capsule endoscopy has a complementary role with cross-sectional imaging to triage patients for appropriate management, including deep enteroscopy, surgery, or, if negative, conservative management. Although capsule endoscopy is useful to detect vascular and inflammatory lesions, it appears to have a significant miss rate for solitary small bowel lesions, including tumors...
February 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28437000/magnetically-guided-capsule-endoscopy
#11
REVIEW
Naveen Shamsudhin, Vladimir I Zverev, Henrik Keller, Salvador Pane, Peter W Egolf, Bradley J Nelson, Alexander M Tishin
Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle-part of the gastrointestinal tract and to identify diseases such as inflammatory bowel disease (Crohn's disease), Polyposis-Syndrome and tumors...
April 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28431493/pan-intestinal-capsule-endoscopy-in-patients-with-postoperative-crohn-s-disease-a-pilot-study
#12
Johannes Hausmann, Renate Schmelz, Jens Walldorf, Natalie Filmann, Stefan Zeuzem, Jörg G Albert
BACKGROUND: Patients are at increased risk of disease recurrence after surgical treatment of Crohn's disease. Endoscopic detection of postoperative, ileo-colonic inflammation is well established, but the potential of pan-intestinal endoscopy is yet unknown. METHODS: This prospective multicenter pilot study assessed the value of pan-intestinal capsule endoscopy using a colon capsule endoscope for the detection of inflammatory recurrence of Crohn´s disease. Patients who had been operatively treated for Crohn´s disease were included...
April 21, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28429597/is-capsule-colonoscopy-the-solution-for-incomplete-conventional-colonoscopy
#13
Miguel Mascarenhas-Saraiva
The era of colon capsule endoscopy (CCE) started in 2007. Few years later second-generation CCE (CCE-2) (Medtronic, Minneapolis, USA) was launched, featuring an improved optical system allowing for nearly 360° coverage via two 172° angle cameras, and adaptive frame rate function (ranging from 4 to 35 images per second depending on capsule motion). At present the main clinical indications for CCE are: a) completion of incomplete colonoscopy; b) polyp detection; and c) investigation of inflammatory bowel disease (IBD)...
April 21, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28412572/quantitative-analysis-of-patients-with-celiac-disease-by-video-capsule-endoscopy-a-deep-learning-method
#14
Teng Zhou, Guoqiang Han, Bing Nan Li, Zhizhe Lin, Edward J Ciaccio, Peter H Green, Jing Qin
BACKGROUND: Celiac disease is one of the most common diseases in the world. Capsule endoscopy is an alternative way to visualize the entire small intestine without invasiveness to the patient. It is useful to characterize celiac disease, but hours are need to manually analyze the retrospective data of a single patient. Computer-aided quantitative analysis by a deep learning method helps in alleviating the workload during analysis of the retrospective videos. METHOD: Capsule endoscopy clips from 6 celiac disease patients and 5 controls were preprocessed for training...
April 8, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28410352/small-bowel-mucosal-healing-assessment-by-capsule-endoscopy-as-a-predictor-of-long-term-clinical-remission-in-patients-with-crohn-s-disease-a-systematic-review-and-meta-analysis
#15
Yaron Niv
Capsule endoscopy (CE) may be used for the evaluation and follow-up of patients with Crohn's disease. CE scores correspond to the degree of mucosal inflammation, a major therapeutic target. The aim of this meta-analysis and systematic review was to determine whether mucosal healing assessment by CE may serve as a predictor of clinical remission in patients with Crohn's disease. To identify observational or controlled English-language full-text studies assessing mucosal healing by CE in patients with Crohn's disease up to 30 September 2016, we searched PubMed, Embase, Central, Medline, and Scopus using the key words 'mucosal healing' and 'capsule endoscopy'...
April 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28408924/investigation-of-small-bowel-abnormalities-in-hiv-infected-patients-using-capsule-endoscopy
#16
Eiji Sakai, Takuma Higurashi, Hidenori Ohkubo, Kuhihiro Hosono, Atsuhisa Ueda, Nobuyuki Matsuhashi, Atsushi Nakajima
HIV infection is reportedly associated with an increased permeability of the intestinal epithelium and can cause HIV enteropathy, which occurs independently of opportunistic infections. However, the characteristics of small bowel abnormalities attributable to HIV infection are rarely investigated. In the present study, we assessed the intestinal mucosal changes found in HIV-infected patients and compared them with the mucosa of healthy control subjects using capsule endoscopy (CE). Three of the 27 HIV-infected patients harbored gastrointestinal opportunistic infections and were thus excluded from subsequent analyses...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28405316/endoscopic-techniques-to-detect-small-bowel-neuroendocrine-tumors-a-literature-review
#17
REVIEW
Roberta Elisa Rossi, Dario Conte, Luca Elli, Federica Branchi, Sara Massironi
BACKGROUND: The diagnosis of small-bowel neuroendocrine tumors (SbNETs) has improved with the advent of video capsule endoscopy (CE) and double-balloon enteroscopy (DBE). The data describing the efficacy of CE/DBE in the detection of SbNETs are scanty. AIM: The aim of this article is to review the current evidence on the role of DBE and CE in the diagnosis of SbNETs. MATERIAL AND METHODS: A bibliographical search was performed in PubMed using the following keywords: "neuroendocrine tumors and enteroscopy/and capsule endoscopy" and "small bowel neuroendocrine tumors...
February 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28391667/quality-indicators-for-small-bowel-capsule-endoscopy
#18
REVIEW
Ki-Nam Shim, Seong Ran Jeon, Hyun Joo Jang, Jinsu Kim, Yun Jeong Lim, Kyeong Ok Kim, Hyun Joo Song, Hyun Seok Lee, Jae Jun Park, Ji Hyun Kim, Jaeyoung Chun, Soo Jung Park, Dong-Hoon Yang, Yang Won Min, Bora Keum, Bo-In Lee
Capsule endoscopy (CE) enables evaluation of the entire mucosal surface of the small bowel (SB), which is one of the most important steps for evaluating obscure gastrointestinal bleeding. Although the diagnostic yield of SB CE depends on many clinical factors, there are no reports on quality indicators. Thus, the Korean Gut Image Study Group (KGISG) publishes an article titled, "Quality Indicators for Small Bowel Capsule Endoscopy" under approval from the Korean Society of Gastrointestinal Endoscopy (KSGE)...
March 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28381855/tapeworms-diagnosed-by-capsule-endoscopy-an-unusual-cause-of-abdominal-pain-in-a-child
#19
Eugenie C Shieh, Gerard E Mullin
No abstract text is available yet for this article.
April 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28372952/the-elipse-balloon-a-swallowable-gastric-balloon-for-weight-loss-not-requiring-sedation-anesthesia-or-endoscopy-a-pilot-study-with-12-month-outcomes
#20
Ioannis Raftopoulos, Andreas Giannakou
BACKGROUND: The Elipse Balloon is a swallowable gastric balloon for weight loss that can be deployed without the use of endoscopy or anesthesia. This study aims to report on 12-month safety and efficacy outcomes. SETTING: Private hospital, Athens, Greece. METHODS: This was a prospective, nonrandomized open trial. Twelve patients between 18 and 64 years of age with a body mass index (BMI) of 27.0 to 40.0 kg/m(2) were enrolled. The Elipse capsule is swallowed with water and its location in the stomach is confirmed by x-ray...
February 21, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
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